Details of Disease

General Information of Disease (ID: DIS5OIP1)

• Disease Name: Coronary heart disease
• Synonyms: coronary arteriosclerosis; coronary artery disease; CHD (coronary heart disease); coronary disease; disease or disorder of coronary artery; coronary artery disease or disorder; disorder of coronary artery; CAD; coronary heart disease; disease of coronary artery; CHD
• Disease Class: BA80: Coronary atherosclerosis
• Definition: Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction. (ACC)
• Disease Hierarchy:
  DISLG4XS: Arterial disorder
  DISWD40R: Disease
  DISVO1I5: Cardiac disease
  DIS5OIP1: Coronary heart disease
• ICD Code:
  ICD-11: ICD-11: BA80.Z
  ICD-9: ICD-9: 414
  Expand ICD-9: 414
• Disease Identifiers:
  MONDO ID: MONDO_0005010
  MESH ID: D003324
  UMLS CUI: C1956346
  MedGen ID: 365486
  SNOMED CT ID: 414024009

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 4 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Probucol	DMVZQ2M	Approved	Small molecular drug	[1]
Sertraline	DM0FB1J	Approved	Small molecular drug	[2]
Simvastatin	DM30SGU	Approved	Small molecular drug	[3]
LAROPIPRANT	DM5FABJ	Phase 4	Small molecular drug	[4]

This Disease is Treated as An Indication in 1 Drugs in Phase 2 Trial

Drug Name	Drug ID	Highest Status	Drug Type	REF
Heparin	DM4ZP3W	Phase 2/3 Trial	Small molecular drug	[5]

This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
CVBT-141H	DMYPXQ2	Phase 2	NA	[6]
FGF-1	DMXMC8I	Phase 2	NA	[7]
MEDI6570	DML8S0W	Phase 2	Antibody	[8]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 359 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ACE2	TTUI5H7	Limited	Altered Expression	[9]
ACR	TTAHE2N	Limited	Biomarker	[10]
ACTG1	TTGAZF9	Limited	Biomarker	[11]
ADAM10	TTVXEGU	Limited	Biomarker	[12]
ADAM33	TTQICM2	Limited	Genetic Variation	[13]
ADAMTS1	TTS2TEI	Limited	Genetic Variation	[14]
ADAMTS4	TTYG6BU	Limited	Biomarker	[15]
ADORA3	TTJFY5U	Limited	Genetic Variation	[16]
ADRA2A	TTWG9A4	Limited	Genetic Variation	[17]
ADRB3	TTMXGCW	Limited	Genetic Variation	[18]
AGTR2	TTQVOEI	Limited	Genetic Variation	[19]
ALDH2	TTFLN4T	Limited	Genetic Variation	[20]
ALOX5	TTSJ6Q4	Limited	Biomarker	[21]
ANGPTL3	TT59GO7	Limited	Genetic Variation	[22]
APOA2	TTGQA9W	Limited	Biomarker	[23]
ARSA	TTYQANR	Limited	Biomarker	[24]
ATXN3	TT6A17J	Limited	Genetic Variation	[25]
BLVRA	TTJBPN3	Limited	Genetic Variation	[26]
BMPR2	TTGKF90	Limited	Genetic Variation	[27]
C3AR1	TTI6B3F	Limited	Biomarker	[28]
C5AR1	TTHXFA1	Limited	Altered Expression	[29]
CA2	TTANPDJ	Limited	Biomarker	[30]
CASP1	TTCQIBE	Limited	Altered Expression	[31]
CCL11	TTCF05Y	Limited	Genetic Variation	[32]
CCL17	TTMPHAE	Limited	Genetic Variation	[33]
CCL21	TTLZK1U	Limited	Biomarker	[34]
CD1A	TTBGTFN	Limited	Altered Expression	[35]
CD59	TTBGTEJ	Limited	Altered Expression	[36]
CES1	TTMF541	Limited	Genetic Variation	[37]
CPB2	TTP18AY	Limited	Genetic Variation	[38]
CPE	TTXPWO6	Limited	Genetic Variation	[39]
CPS1	TT42M75	Limited	Biomarker	[40]
CTSS	TTUMQVO	Limited	Biomarker	[41]
CX3CL1	TT1OFBQ	Limited	Genetic Variation	[42]
CYP3A5	TTHS0OK	Limited	Genetic Variation	[43]
ELANE	TTPLTSQ	Limited	Biomarker	[44]
ENPP1	TTZTIWS	Limited	Genetic Variation	[45]
EPO	TTQG4NR	Limited	Biomarker	[46]
ESR2	TTOM3J0	Limited	Biomarker	[47]
F11	TTDM4ZU	Limited	Biomarker	[48]
F11R	TT3C8EG	Limited	Genetic Variation	[49]
F12	TTRJSMV	Limited	Genetic Variation	[50]
F8	TT1290U	Limited	Altered Expression	[51]
FCGR2B	TT5RWKQ	Limited	Biomarker	[52]
FGG	TTR31L7	Limited	Genetic Variation	[53]
FN1	TTPJ921	Limited	Altered Expression	[54]
G3BP1	TTG0R8Z	Limited	Biomarker	[55]
GCG	TT6Y4PN	Limited	Altered Expression	[56]
GGT1	TTZVT7O	Limited	Altered Expression	[57]
GLP2R	TT1YWO5	Limited	Biomarker	[58]
GRIK4	TTQV6BO	Limited	Biomarker	[59]
GSTA1	TT4P8DE	Limited	Genetic Variation	[60]
HNF1A	TT01M3K	Limited	Genetic Variation	[61]
HSPA8	TTMQL3K	Limited	Genetic Variation	[62]
IFNL3	TTRF4Q2	Limited	Genetic Variation	[63]
IL15	TTJFA35	Limited	Biomarker	[64]
IL15RA	TTGN89I	Limited	Altered Expression	[65]
IL16	TTW4R0B	Limited	Genetic Variation	[66]
IL18	TTRICUF	Limited	Altered Expression	[31]
IL1RL1	TT4GZA4	Limited	Biomarker	[67]
IL23R	TT6H4QR	Limited	Genetic Variation	[68]
IL5	TTPREZD	Limited	Biomarker	[69]
IRF8	TTHUBNK	Limited	Genetic Variation	[70]
ITGA2	TTSJ542	Limited	Genetic Variation	[71]
JUP	TTREN0G	Limited	Biomarker	[72]
KLK1	TT5T3P6	Limited	Biomarker	[73]
LAG3	TTNVXAW	Limited	Altered Expression	[74]
LAMP2	TTULDG7	Limited	Biomarker	[75]
LBP	TTVQJLY	Limited	Biomarker	[76]
LCAT	TTGZ91P	Limited	Genetic Variation	[77]
LIPA	TTS8T1M	Limited	Biomarker	[78]
LTA4H	TTXZEAJ	Limited	Altered Expression	[79]
MAP2K2	TT8H9GB	Limited	Altered Expression	[80]
MAP3K8	TTGECUM	Limited	Altered Expression	[81]
MIA	TT5HNVS	Limited	Genetic Variation	[82]
MSR1	TT2TDH9	Limited	Altered Expression	[83]
MTNR1A	TT0WAIE	Limited	Genetic Variation	[84]
MTTP	TTUS1RD	Limited	Biomarker	[85]
MUC16	TTC1PS3	Limited	Biomarker	[86]
MVD	TTE5J6X	Limited	Genetic Variation	[87]
MVK	TT5DFHW	Limited	Genetic Variation	[88]
MYBPC3	TT9WOBN	Limited	Genetic Variation	[89]
NFKB1	TTUIZKC	Limited	Genetic Variation	[90]
NPFFR2	TTXYNDJ	Limited	Altered Expression	[91]
NPR1	TTM9IYA	Limited	Genetic Variation	[92]
NPR3	TTWVLS6	Limited	Altered Expression	[93]
NR1H3	TTECBXN	Limited	Genetic Variation	[94]
NR3C2	TT26PHO	Limited	Biomarker	[95]
OGDH	TTH8T6I	Limited	Altered Expression	[96]
OPA1	TTTU49Q	Limited	Biomarker	[97]
P2RY12	TTZ1DT0	Limited	Biomarker	[98]
PCSK1	TTED9LZ	Limited	Genetic Variation	[99]
PECAM1	TT4EZB2	Limited	Genetic Variation	[61]
PF4	TTSG7Q5	Limited	Biomarker	[100]
PLG	TTP86E2	Limited	Biomarker	[101]
PPIA	TTL2ADK	Limited	Genetic Variation	[102]
PRKCH	TTONI0R	Limited	Genetic Variation	[103]
PYY	TTVFJLX	Limited	Altered Expression	[104]
RENBP	TTZCG0Q	Limited	Biomarker	[105]
SAA1	TTY0DN9	Limited	Genetic Variation	[106]
SCARB1	TTRE324	Limited	Genetic Variation	[107]
SELL	TT2IYXF	Limited	Biomarker	[108]
SENP1	TTW9HY5	Limited	Biomarker	[109]
SERPINC1	TT4QPUL	Limited	Genetic Variation	[25]
SFRP4	TTX8I1Y	Limited	Altered Expression	[110]
SH2B3	TT36N7Z	Limited	Genetic Variation	[61]
SLC2A4	TTP6MT5	Limited	Altered Expression	[111]
SLCO1B1	TTFGXEB	Limited	Genetic Variation	[112]
SPOCK1	TTF23RE	Limited	Altered Expression	[113]
SRGN	TTCHB06	Limited	Altered Expression	[114]
SUV39H1	TTUWQTK	Limited	Biomarker	[115]
TBXA2R	TT2O84V	Limited	Altered Expression	[116]
TCF7L2	TT80QAL	Limited	Altered Expression	[117]
TERF2	TT5XSLT	Limited	Altered Expression	[118]
THRA	TTTSEPU	Limited	Genetic Variation	[119]
TIAM1	TTNU6I5	Limited	Genetic Variation	[120]
TLR1	TTW14D0	Limited	Genetic Variation	[121]
TLR8	TT8CWFK	Limited	Genetic Variation	[122]
TNC	TTUCPMY	Limited	Biomarker	[123]
TNFAIP3	TT5W0IO	Limited	Genetic Variation	[124]
TNFRSF11B	TT2CJ75	Limited	Biomarker	[125]
TNFRSF4	TTL31H0	Limited	Biomarker	[126]
TNFSF4	TTBW580	Limited	Biomarker	[127]
TREM1	TTHZQP0	Limited	Genetic Variation	[121]
TRPA1	TTELV3W	Limited	Genetic Variation	[128]
UBC	TTBP3XA	Limited	Altered Expression	[129]
UCP1	TTI12YJ	Limited	Biomarker	[93]
UCP2	TTSC2YM	Limited	Genetic Variation	[130]
UCP3	TT12RJK	Limited	Genetic Variation	[131]
VIP	TTGTWLF	Limited	Biomarker	[132]
VKORC1	TTEUC8H	Limited	Genetic Variation	[133]
ZNF217	TTY3BRA	Limited	Genetic Variation	[134]
ACACB	TTY84UG	Disputed	Genetic Variation	[135]
ACAT1	TTK3C21	Disputed	Genetic Variation	[37]
ALCAM	TT2AFT6	Disputed	Biomarker	[136]
CTH	TTLQUZS	Disputed	Genetic Variation	[137]
IFNGR2	TT13TL0	Disputed	Biomarker	[138]
LTC4S	TTW7OTG	Disputed	Biomarker	[79]
NPPC	TTRK0B9	Disputed	Biomarker	[139]
PADI4	TTQHAXM	Disputed	Biomarker	[140]
SLC25A1	TTTD730	Disputed	Biomarker	[141]
SLC27A4	TT20AYF	Disputed	Biomarker	[142]
SOAT2	TTAK0IN	Disputed	Genetic Variation	[143]
TNFSF14	TTKVENM	Disputed	Biomarker	[144]
ABL2	TT1A6HL	moderate	Genetic Variation	[145]
ADAM8	TTQWYMD	moderate	Altered Expression	[146]
ATXN2	TTPQJ7P	moderate	Genetic Variation	[61]
BMP1	TT0L58T	moderate	Genetic Variation	[61]
C1S	TT7LRQH	moderate	Genetic Variation	[61]
C5	TTKANGO	moderate	Genetic Variation	[61]
CA13	TTQPHSR	moderate	Genetic Variation	[147]
CALCRL	TTY6O0Q	moderate	Altered Expression	[148]
CD36	TTPJMCU	moderate	Genetic Variation	[149]
CDH2	TT1WS0T	moderate	Genetic Variation	[150]
CFB	TTA0P7K	moderate	Genetic Variation	[61]
CHRNB4	TTTVAFQ	moderate	Genetic Variation	[151]
CSK	TTX6F0Q	moderate	Genetic Variation	[152]
CXCL11	TTWG0RE	moderate	Altered Expression	[153]
CYP21A2	TTP4GLG	moderate	Genetic Variation	[61]
DAGLB	TTXZDEN	moderate	Genetic Variation	[61]
DCLK2	TTHK3MO	moderate	Genetic Variation	[128]
DMPK	TTZQTY2	moderate	Biomarker	[154]
FER	TTRA9G0	moderate	Genetic Variation	[155]
FES	TTLBY21	moderate	Genetic Variation	[61]
FKBP5	TT0J5KQ	moderate	Genetic Variation	[61]
FUT3	TTUPAD7	moderate	Genetic Variation	[156]
GCH1	TTLSWP6	moderate	Genetic Variation	[157]
GGCX	TT76OLR	moderate	Genetic Variation	[158]
GGT7	TT62BC7	moderate	Genetic Variation	[61]
GJA4	TTQO1VY	moderate	Biomarker	[159]
HBEGF	TT15SL0	moderate	Altered Expression	[160]
HCAR2	TTWNV8U	moderate	Biomarker	[161]
HGFAC	TTD96RW	moderate	Genetic Variation	[61]
HMGCR	TTPADOQ	moderate	Genetic Variation	[162]
HTRA1	TT8POQR	moderate	Genetic Variation	[61]
MAD1L1	TTNE9U7	moderate	Genetic Variation	[61]
MAS1	TTOISYB	moderate	Biomarker	[9]
MAT2A	TTSMPXQ	moderate	Genetic Variation	[163]
NEDD9	TT1UREA	moderate	Genetic Variation	[61]
NEK9	TTM57AW	moderate	Genetic Variation	[61]
NOD1	TTYSRXM	moderate	Genetic Variation	[164]
PAX5	TTA4REJ	moderate	Genetic Variation	[165]
PDGFA	TTSM78N	moderate	Genetic Variation	[166]
PEPD	TTLZXI0	moderate	Altered Expression	[167]
PHB	TT6U071	moderate	Genetic Variation	[61]
PLCG1	TT6T4JI	moderate	Genetic Variation	[61]
PPARA	TTJ584C	moderate	Biomarker	[168]
PROC	TTZUXYS	moderate	Genetic Variation	[169]
PTGER2	TT1ZAVI	moderate	Genetic Variation	[170]
PTK7	TTXH2ZN	moderate	Genetic Variation	[61]
RHOA	TTP2U16	moderate	Genetic Variation	[61]
RPH3A	TT9L4J8	moderate	Genetic Variation	[151]
SELP	TTE5VG0	moderate	Genetic Variation	[171]
SERPINH1	TTPSWQG	moderate	Genetic Variation	[61]
SLC22A3	TTG2UMS	moderate	Genetic Variation	[172]
SLC26A4	TT7X02I	moderate	Genetic Variation	[173]
SLC2A12	TTZO36H	moderate	Genetic Variation	[61]
ST8SIA4	TTDP8YM	moderate	Genetic Variation	[174]
TENT4A	TT0XZ4Q	moderate	Genetic Variation	[61]
TNNT2	TTWAS18	moderate	Biomarker	[175]
TOR1A	TTF85KW	moderate	Altered Expression	[176]
TRPC3	TTNVC34	moderate	Biomarker	[177]
TRPM3	TTO3TD8	moderate	Genetic Variation	[163]
UMPS	TTAFJUD	moderate	Genetic Variation	[61]
ZEB2	TTT2WK4	moderate	Genetic Variation	[61]
ABCG5	TTKZ7WY	Strong	Genetic Variation	[178]
ACHE	TT1RS9F	Strong	Altered Expression	[179]
ADA	TTLP57V	Strong	Altered Expression	[180]
ADAMTS13	TTUREBK	Strong	Biomarker	[181]
ADAMTS5	TTXSU2Y	Strong	Biomarker	[182]
ADRA2B	TTWM4TY	Strong	Biomarker	[183]
ADRB1	TTR6W5O	Strong	Genetic Variation	[184]
AHSG	TTKF4WV	Strong	Altered Expression	[185]
ALOX15	TTN9T81	Strong	Genetic Variation	[186]
ALPL	TTMR5UV	Strong	Altered Expression	[187]
ANPEP	TTPHMWB	Strong	Biomarker	[188]
AOC3	TT7HC21	Strong	Biomarker	[189]
APLN	TT87D3J	Strong	Altered Expression	[190]
APLNR	TTJ8E43	Strong	Genetic Variation	[191]
APOA4	TTNC3WS	Strong	Biomarker	[192]
APOC3	TTXOZQ1	Strong	Biomarker	[193]
ARG1	TT7ZQEV	Strong	Altered Expression	[194]
ARRB2	TT8SO2I	Strong	Biomarker	[195]
ASGR1	TTYM94H	Strong	Altered Expression	[196]
BCHE	TT3MSAO	Strong	Altered Expression	[197]
BDKRB1	TTG5QIA	Strong	Altered Expression	[198]
BDKRB2	TTGY8IW	Strong	Altered Expression	[198]
CACNA1C	TTZIFHC	Strong	Genetic Variation	[199]
CCN1	TTPK79J	Strong	Biomarker	[200]
CCR7	TT2GIDQ	Strong	Genetic Variation	[201]
CD28	TTQ13FT	Strong	Biomarker	[42]
CD40	TT1ERKL	Strong	Genetic Variation	[202]
CD69	TTPQE9F	Strong	Biomarker	[203]
CDK18	TTUMFAR	Strong	Genetic Variation	[165]
CFTR	TTRLZHP	Strong	Genetic Variation	[61]
CR1	TTEA8OW	Strong	Altered Expression	[36]
CTSG	TTQAJF1	Strong	Biomarker	[204]
CXCL12	TT4UGTF	Strong	Genetic Variation	[205]
CYP17A1	TTRA5BZ	Strong	Genetic Variation	[206]
CYP2B6	TTMH124	Strong	Genetic Variation	[207]
CYP2C9	TTR40YJ	Strong	Genetic Variation	[208]
CYP3A4	TTWP7HQ	Strong	Biomarker	[209]
DFFA	TTYVQ9C	Strong	Biomarker	[210]
DIO1	TTU3X26	Strong	Genetic Variation	[211]
ECE1	TTQ9RYT	Strong	Genetic Variation	[212]
EHMT1	TTOFXD7	Strong	Genetic Variation	[213]
F10	TTCIHJA	Strong	Biomarker	[214]
F2R	TTL935N	Strong	Genetic Variation	[215]
F2RL3	TTD0652	Strong	Posttranslational Modification	[216]
F3	TT38MDJ	Strong	Biomarker	[217]
F7	TTF0EGX	Strong	Genetic Variation	[218]
FABP3	TT3TGLR	Strong	Biomarker	[219]
FCGR2A	TTXT21W	Strong	Biomarker	[220]
FCGR3A	TTIFOC0	Strong	Biomarker	[221]
FGF21	TTQ916P	Strong	Altered Expression	[222]
FGFR4	TT1KX2S	Strong	Genetic Variation	[223]
FOLH1	TT9G4N0	Strong	Genetic Variation	[224]
FURIN	TTH9WF6	Strong	Genetic Variation	[61]
GCLM	TTNFESW	Strong	Biomarker	[225]
GDF15	TT4MXVG	Strong	Altered Expression	[226]
GDF2	TTAP4T1	Strong	Biomarker	[227]
GIP	TT40HS5	Strong	Genetic Variation	[61]
GLP1R	TTVIMDE	Strong	Genetic Variation	[213]
GP1BA	TTVB0Q9	Strong	Genetic Variation	[228]
GPX1	TTYAHBP	Strong	Biomarker	[229]
GREM1	TTOUZN5	Strong	Altered Expression	[230]
HDAC9	TT8M4E1	Strong	Genetic Variation	[231]
HMGB1	TTWQYB7	Strong	Biomarker	[232]
HPGDS	TTCYE56	Strong	Genetic Variation	[233]
HPSE	TTR7GJO	Strong	Biomarker	[234]
HSPD1	TT9HL5R	Strong	Genetic Variation	[235]
IGF2R	TTPNE41	Strong	Biomarker	[236]
IL1R2	TT51DEV	Strong	Biomarker	[195]
IL33	TT5MD4P	Strong	Altered Expression	[237]
IL37	TTQTX98	Strong	Altered Expression	[238]
IRS1	TTAJSQ0	Strong	Altered Expression	[239]
ITGA1	TTPERWV	Strong	Genetic Variation	[128]
KDM3A	TTKXS4A	Strong	Biomarker	[240]
KNG1	TTDJ4MY	Strong	Biomarker	[241]
LCK	TT860QF	Strong	Genetic Variation	[242]
LEPR	TT0HD6V	Strong	Genetic Variation	[243]
LGALS2	TTRHK90	Strong	Altered Expression	[244]
LOX	TTQHNAM	Strong	Genetic Variation	[245]
LRP6	TTSXOWE	Strong	Biomarker	[117]
MARK2	TTAJ45Y	Strong	Genetic Variation	[246]
MBL2	TTMQDZ5	Strong	Genetic Variation	[247]
MC4R	TTD0CIQ	Strong	Genetic Variation	[248]
MFGE8	TT1GLAJ	Strong	Altered Expression	[249]
MGAM	TTXWASR	Strong	Biomarker	[250]
MMP12	TTXZ0KQ	Strong	Altered Expression	[251]
MMP7	TTMTWOS	Strong	Genetic Variation	[252]
MMP8	TTGA1IV	Strong	Biomarker	[253]
MTR	TTUTO39	Strong	Genetic Variation	[254]
MUSK	TT6SA0X	Strong	Genetic Variation	[255]
NAGLU	TTDM6HZ	Strong	Biomarker	[11]
NAMPT	TTD1WIG	Strong	Altered Expression	[256]
NPC1L1	TTPD1CN	Strong	Altered Expression	[257]
NPPB	TTY63XT	Strong	Genetic Variation	[258]
NPR2	TTNB7IF	Strong	Altered Expression	[93]
NRG4	TTWAGKJ	Strong	Altered Expression	[259]
NTF3	TTZHKV9	Strong	Biomarker	[136]
NTN1	TT0AH4L	Strong	Altered Expression	[238]
OTC	TT5KIO9	Strong	Biomarker	[260]
P2RY1	TTA93TL	Strong	Genetic Variation	[261]
PCSK6	TT75LN9	Strong	Altered Expression	[262]
PDE3B	TTN34SQ	Strong	Genetic Variation	[263]
PDE4D	TTSKMI8	Strong	Genetic Variation	[264]
PDGFD	TTSN0GA	Strong	Genetic Variation	[265]
PLTP	TTZF6SN	Strong	Altered Expression	[266]
PPARD	TT2JWF6	Strong	Altered Expression	[267]
PRKCE	TT57MT2	Strong	Genetic Variation	[61]
PTGS2	TTVKILB	Strong	Altered Expression	[268]
PTH	TT6F7GZ	Strong	Biomarker	[269]
PTPRC	TTUS45N	Strong	Biomarker	[270]
RBP4	TT0C8BY	Strong	Altered Expression	[238]
RTN4	TT7GXMU	Strong	Altered Expression	[182]
S100A12	TTQ4ESF	Strong	Biomarker	[271]
S100A8	TT4AF6N	Strong	Biomarker	[195]
S1PR4	TTZ8C5Q	Strong	Biomarker	[272]
SCD	TT6RIOV	Strong	Genetic Variation	[255]
SERPINF1	TTR59S1	Strong	Altered Expression	[273]
SLC52A2	TT6TKEN	Strong	Genetic Variation	[246]
SLC5A2	TTF8JAT	Strong	Genetic Variation	[274]
SLCO1C1	TT340CE	Strong	Genetic Variation	[211]
SMAD3	TTHQZV7	Strong	Genetic Variation	[61]
SORT1	TTRX9AV	Strong	Biomarker	[275]
SREBF1	TTER0UB	Strong	Biomarker	[276]
SREBF2	TTRQ4AP	Strong	Biomarker	[277]
TEK	TT9VGXW	Strong	Genetic Variation	[61]
TERF1	TT1Y6J2	Strong	Altered Expression	[278]
TERT	TTQY2EJ	Strong	Biomarker	[279]
TFPI	TT068JH	Strong	Genetic Variation	[280]
THBS1	TTKI0H1	Strong	Genetic Variation	[281]
TMSB4X	TTMVAIU	Strong	Genetic Variation	[282]
TNFRSF1A	TTG043C	Strong	Biomarker	[283]
TNFRSF1B	TT63WSF	Strong	Biomarker	[283]
TNFSF15	TTEST6I	Strong	Biomarker	[284]
TNNI3	TTNLDK6	Strong	Altered Expression	[285]
TRAF6	TTCDR6M	Strong	Genetic Variation	[286]
UTS2	TTERU0T	Strong	Altered Expression	[287]
VCAM1	TTHCEF6	Strong	Altered Expression	[288]
YOD1	TTFSH0K	Strong	Biomarker	[289]
CDH3	TTARMD9	Definitive	Genetic Variation	[290]
CEL	TTTRNQW	Definitive	Biomarker	[291]
CFD	TT8D13I	Definitive	Biomarker	[292]
CRLF2	TTRMZ0N	Definitive	Biomarker	[293]
FCGR1A	TTZK4I3	Definitive	Altered Expression	[294]
FGF19	TTGCH11	Definitive	Biomarker	[295]
HMGB2	TTA78JQ	Definitive	Altered Expression	[296]
JMJD1C	TTBISK4	Definitive	Genetic Variation	[297]
LCT	TTA0OSE	Definitive	Biomarker	[298]
MAG	TT9XFON	Definitive	Biomarker	[299]
POR	TTOQ9GZ	Definitive	Altered Expression	[300]
PTAFR	TTQL5VC	Definitive	Genetic Variation	[301]
RRM1	TTWP0NS	Definitive	Genetic Variation	[302]
SETD7	TTJ0FSU	Definitive	Biomarker	[303]
SIRT5	TTH0IOD	Definitive	Genetic Variation	[304]
TNFRSF13C	TT7NJSE	Definitive	Biomarker	[305]
ZAP70	TTUMHT8	Definitive	Biomarker	[306]

This Disease Is Related to 12 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
ABCB5	DTKVEXO	Limited	Genetic Variation	[307]
ATP2B1	DTJWQ1L	Limited	Biomarker	[308]
SLC25A20	DTQOUM4	Limited	Biomarker	[30]
SLC2A6	DTS4MKQ	Limited	Genetic Variation	[309]
SLC7A13	DTMWE5P	Limited	Biomarker	[310]
ABCC10	DTPS120	moderate	Genetic Variation	[61]
ANXA11	DTGQ2CF	moderate	Genetic Variation	[151]
KCNH7	DT3WXPI	moderate	Genetic Variation	[61]
SLC22A4	DT2EG60	moderate	Genetic Variation	[61]
ABCC6	DT582KR	Strong	Genetic Variation	[311]
SLC35A1	DTVZIRG	Strong	Biomarker	[312]
SLCO6A1	DTIFXNS	Strong	Genetic Variation	[313]

This Disease Is Related to 32 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
ADH1B	DEEN9RD	Limited	Genetic Variation	[314]
ALDH1B1	DEXI4UQ	Limited	Genetic Variation	[315]
CYP27A1	DEBS639	Limited	Genetic Variation	[316]
CYP2C18	DEZMWRE	Limited	Genetic Variation	[317]
CYP2R1	DEBIHM3	Limited	Genetic Variation	[318]
CYP4A11	DE2XQGW	Limited	Biomarker	[319]
DDAH1	DEY0TQC	Limited	Genetic Variation	[320]
MSRA	DEU2ZBY	Limited	Genetic Variation	[321]
MT2A	DEFKGT7	Limited	Genetic Variation	[322]
SULT1E1	DESTKG6	Limited	Biomarker	[323]
ACSS2	DEE76VW	Strong	Biomarker	[324]
ADH1C	DEM1HNL	Strong	Genetic Variation	[325]
AKR1A1	DED2FW3	Strong	Genetic Variation	[326]
AOC2	DE8DP90	Strong	Biomarker	[189]
AS3MT	DE9KJP3	Strong	Genetic Variation	[61]
CES2	DETHCPD	Strong	Biomarker	[327]
CPA4	DEXKD7J	Strong	Biomarker	[204]
CYP4F2	DE3GT9C	Strong	Biomarker	[319]
CYP7A1	DEDZRQ1	Strong	Genetic Variation	[328]
DHCR7	DEL7GFA	Strong	Genetic Variation	[329]
FAAH	DEUM1EX	Strong	Biomarker	[330]
FADS1	DE05S8C	Strong	Genetic Variation	[255]
GCLC	DESYL1F	Strong	Biomarker	[225]
GSTM1	DEYZEJA	Strong	Biomarker	[233]
GSTT1	DE3PKUG	Strong	Genetic Variation	[233]
MTARC2	DE6QH2D	Strong	Biomarker	[331]
NADSYN1	DELF8BA	Strong	Genetic Variation	[329]
NAT2	DER7TA0	Strong	Genetic Variation	[332]
NNMT	DECVGJ3	Strong	Genetic Variation	[333]
PON2	DEHJU7E	Strong	Biomarker	[334]
SI	DE5EO4Y	Strong	Biomarker	[250]
ACP5	DESITDW	Definitive	Biomarker	[335]

This Disease Is Related to 566 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ABCG8	OTIJ76XW	Limited	Genetic Variation	[61]
ABRAXAS2	OTAW1I4C	Limited	Altered Expression	[336]
ACACA	OT5CQPZY	Limited	Biomarker	[337]
ACKR2	OTWYY14H	Limited	Biomarker	[338]
ADAMTSL4	OTBILJMW	Limited	Genetic Variation	[339]
ADAR	OTQNOHR8	Limited	Altered Expression	[340]
ADD1	OTTF68DC	Limited	Genetic Variation	[341]
ADIPOR2	OT2HDTL8	Limited	Altered Expression	[342]
AGGF1	OTA7U2T8	Limited	Biomarker	[343]
AGXT2	OTO6QUTM	Limited	Genetic Variation	[320]
AIDA	OTMRLWGT	Limited	Altered Expression	[344]
ALOX15B	OTWQQ08W	Limited	Genetic Variation	[345]
AMFR	OTQRX7LC	Limited	Genetic Variation	[346]
ANP32B	OT3SQMLU	Limited	Altered Expression	[347]
APEX2	OTJ22LIT	Limited	Genetic Variation	[53]
APOC4	OTE8ZUXY	Limited	Genetic Variation	[348]
APPL1	OT8VR95S	Limited	Genetic Variation	[349]
APPL2	OT9S4C4K	Limited	Genetic Variation	[349]
ARHGAP31	OTUYTF4I	Limited	Biomarker	[350]
ARHGEF7	OT9BPJCL	Limited	Genetic Variation	[351]
ASCC1	OTH4VAP9	Limited	Genetic Variation	[351]
ASXL1	OTX931AW	Limited	Biomarker	[352]
ATP6AP2	OT0IABVV	Limited	Genetic Variation	[353]
B4GALNT1	OTCY80HS	Limited	Biomarker	[354]
BCAR1	OTKT2C2N	Limited	Genetic Variation	[355]
BHMT	OTYB6PXZ	Limited	Genetic Variation	[356]
BMS1	OTEGQ8ZO	Limited	Biomarker	[337]
BRINP3	OT4VFHWN	Limited	Genetic Variation	[357]
BTN2A1	OTUYPMZJ	Limited	Genetic Variation	[358]
C1QL3	OT4TZH3J	Limited	Altered Expression	[359]
C1QTNF1	OT7I7KHC	Limited	Altered Expression	[360]
C1QTNF3	OTOJMWW0	Limited	Biomarker	[361]
C1QTNF9	OTLI3VA3	Limited	Biomarker	[362]
CAMTA1	OTAN1S5B	Limited	Biomarker	[363]
CAP1	OTYM8A2N	Limited	Biomarker	[364]
CBLIF	OTNE20WU	Limited	Altered Expression	[365]
CCL13	OTNX0JD0	Limited	Biomarker	[366]
CCL19	OTQ2UJMH	Limited	Biomarker	[34]
CD93	OT6HZT6H	Limited	Biomarker	[367]
CDKAL1	OTA0SGNE	Limited	Biomarker	[368]
CHGA	OTXYX5JH	Limited	Altered Expression	[369]
CIDEB	OT873IYM	Limited	Biomarker	[370]
CLOCK	OTNEOJY7	Limited	Altered Expression	[371]
CMTM5	OTMS7NDP	Limited	Biomarker	[372]
CNBP	OTTGM9NK	Limited	Genetic Variation	[373]
COG6	OTDLQITC	Limited	Genetic Variation	[374]
COL14A1	OTLNJ13O	Limited	Posttranslational Modification	[375]
COMP	OTS2FPMI	Limited	Altered Expression	[376]
CORT	OTX3GUHB	Limited	Biomarker	[377]
COX1	OTG3O9BN	Limited	Altered Expression	[378]
COX5A	OTP0961M	Limited	Genetic Variation	[379]
CPOX	OTIAY121	Limited	Genetic Variation	[379]
CXCL6	OTFTCQ4O	Limited	Genetic Variation	[380]
CYTB	OTAHB98A	Limited	Biomarker	[381]
DCLRE1C	OTW3KB1I	Limited	Biomarker	[382]
DLD	OT378CU9	Limited	Biomarker	[383]
DNTT	OTFSEF12	Limited	Biomarker	[384]
DOCK11	OTFSTN6A	Limited	Genetic Variation	[385]
DUOX1	OTQ2AEW0	Limited	Genetic Variation	[386]
DUOX2	OTU14HCN	Limited	Genetic Variation	[386]
DYM	OTQ670WI	Limited	Biomarker	[387]
EGR3	OTGPJIRA	Limited	Genetic Variation	[388]
ELAVL2	OT6EJ8MQ	Limited	Biomarker	[389]
ELMO1	OTY2ORXK	Limited	Biomarker	[390]
ELOVL2	OTDAF6U3	Limited	Genetic Variation	[391]
ENHO	OT91QASK	Limited	Biomarker	[392]
ERCC5	OTQAKFJM	Limited	Genetic Variation	[393]
ESYT3	OTG5H3YF	Limited	Genetic Variation	[394]
FAT4	OT7QONNV	Limited	Altered Expression	[116]
FBN2	OT3KYJQL	Limited	Genetic Variation	[15]
FCGR2C	OTNLMNYB	Limited	Biomarker	[52]
FEN1	OT6QGG7O	Limited	Genetic Variation	[395]
FLOT2	OTZ0QR5L	Limited	Genetic Variation	[396]
FLYWCH1	OTWZVRX2	Limited	Biomarker	[55]
FSD1	OT8P6PT3	Limited	Biomarker	[397]
FSD1L	OTBQ48RF	Limited	Biomarker	[397]
GALNT3	OT7M67WT	Limited	Genetic Variation	[398]
GGTLC1	OTWJKUHQ	Limited	Genetic Variation	[399]
GOLGA4	OTCMEHNJ	Limited	Genetic Variation	[380]
GPD1L	OTVLWW9T	Limited	Biomarker	[400]
GPIHBP1	OTDF8R2M	Limited	Biomarker	[401]
GRK4	OTUU8V2S	Limited	Genetic Variation	[402]
GSTM2	OTG4WT05	Limited	Genetic Variation	[403]
GUCY1A1	OTPTCBUN	Limited	Genetic Variation	[404]
HAND2	OTCXYW4Y	Limited	Genetic Variation	[405]
HBG2	OT4J48JJ	Limited	Altered Expression	[406]
HHEX	OTLIUVYX	Limited	Biomarker	[368]
HLA-E	OTX1CTFB	Limited	Genetic Variation	[407]
HLA-F	OT76CM19	Limited	Genetic Variation	[407]
HNRNPUL1	OTJP4U7K	Limited	Genetic Variation	[408]
HPSE2	OTGEPP8V	Limited	Genetic Variation	[409]
HSPA14	OTZCA5LK	Limited	Genetic Variation	[235]
HTRA2	OTC7616F	Limited	Biomarker	[410]
IARS1	OT9WXH5N	Limited	Genetic Variation	[411]
IFNE	OTXO5MHZ	Limited	Genetic Variation	[412]
IL34	OTZ15VVK	Limited	Altered Expression	[413]
IL6R	OTCQL07Z	Limited	Genetic Variation	[61]
IRF2	OTAZRUW3	Limited	Biomarker	[370]
IRF2BP2	OTSSRRCA	Limited	Altered Expression	[414]
IRF6	OTKJ44EV	Limited	Biomarker	[415]
ITLN1	OT7ZLJVV	Limited	Altered Expression	[416]
JCAD	OT7G1WJW	Limited	Genetic Variation	[417]
KALRN	OT8WRCBH	Limited	Genetic Variation	[418]
KCTD10	OT5HFZXU	Limited	Genetic Variation	[419]
KIDINS220	OTLBH2MA	Limited	Genetic Variation	[420]
KIF2B	OTLPAX4N	Limited	Genetic Variation	[421]
KIF2C	OTJ8G3NP	Limited	Genetic Variation	[422]
KRT5	OTVGI9HT	Limited	Biomarker	[423]
LAD1	OT6YGTVX	Limited	Biomarker	[383]
LDB2	OT6Y8IEK	Limited	Altered Expression	[424]
LMAN1	OTYHKDEO	Limited	Genetic Variation	[425]
LSAMP	OTYXVQX2	Limited	Biomarker	[426]
LUM	OTSRC874	Limited	Biomarker	[11]
MADD	OTUFYVGG	Limited	Genetic Variation	[224]
MAFB	OTH2N3T8	Limited	Genetic Variation	[427]
MAP1B	OTVXW089	Limited	Biomarker	[428]
MAX	OTKZ0YKM	Limited	Biomarker	[370]
MCFD2	OTM0XU0U	Limited	Genetic Variation	[425]
MIA3	OTBVIZQD	Limited	Genetic Variation	[205]
MIP	OTEBLU3E	Limited	Altered Expression	[429]
MMD	OTB5I4OC	Limited	Biomarker	[430]
MON2	OTCSVMAR	Limited	Biomarker	[221]
MPHOSPH6	OT6E2S48	Limited	Biomarker	[431]
MPI	OTBH6ZK1	Limited	Biomarker	[432]
MVP	OTJGHJRB	Limited	Genetic Variation	[433]
MYLIP	OTL0PFGV	Limited	Genetic Variation	[434]
NANOS3	OTGX9IQU	Limited	Genetic Variation	[435]
NCF2	OTAUW7L2	Limited	Biomarker	[272]
NDST4	OTEKG7JJ	Limited	Genetic Variation	[436]
NDUFAB1	OTF906UR	Limited	Genetic Variation	[437]
NEXN	OTKB0B0H	Limited	Altered Expression	[438]
NOX5	OTHTH59G	Limited	Biomarker	[439]
NUCB2	OTHO6JWN	Limited	Altered Expression	[440]
NUMB	OTMB586Q	Limited	Genetic Variation	[441]
OGFOD1	OTTUQ5O3	Limited	Genetic Variation	[442]
PAFAH2	OTSHD5M5	Limited	Biomarker	[443]
PCLAF	OTMVIOUU	Limited	Genetic Variation	[444]
PF4V1	OT2CXM6L	Limited	Biomarker	[100]
PLA2G2D	OTU604XM	Limited	Biomarker	[445]
PLA2G5	OTQRSKCZ	Limited	Genetic Variation	[446]
PLEKHG5	OTL0S21W	Limited	Genetic Variation	[120]
PLIN2	OTRXJ9UN	Limited	Altered Expression	[447]
PLPP3	OTSSF7BK	Limited	Genetic Variation	[448]
PPBP	OT1FHGQS	Limited	Biomarker	[449]
PPIG	OTZ8BTTM	Limited	Biomarker	[450]
PRDM10	OTDDWU5Q	Limited	Genetic Variation	[451]
PRORP	OTWIS44P	Limited	Genetic Variation	[452]
PTPRA	OTZA82J1	Limited	Genetic Variation	[433]
PTPRD	OTZPJ3GX	Limited	Biomarker	[453]
QRSL1	OTJDU2UG	Limited	Genetic Variation	[338]
RECQL5	OTVZMP1Q	Limited	Autosomal recessive	[454]
RHOJ	OTWI65OA	Limited	Biomarker	[455]
RNF13	OT7HNYF4	Limited	Genetic Variation	[128]
RNF39	OTUQA9JT	Limited	Biomarker	[456]
RPN1	OTEG4KU9	Limited	Biomarker	[338]
RSPH6A	OTJ96T2F	Limited	Genetic Variation	[457]
S100A7	OTJFVJRF	Limited	Biomarker	[458]
SCAI	OTAK3TMO	Limited	Genetic Variation	[459]
SH2B1	OTJZO2CI	Limited	Genetic Variation	[460]
SHC1	OT1J5IRN	Limited	Altered Expression	[461]
SKIL	OTNBXH32	Limited	Altered Expression	[462]
SNRNP70	OTP52YZ3	Limited	Genetic Variation	[463]
SOD3	OTIOZQAB	Limited	Genetic Variation	[464]
SPESP1	OTWXKKTJ	Limited	Genetic Variation	[465]
SRSF1	OTF61HOV	Limited	Genetic Variation	[466]
SRSF2	OTVDHO6U	Limited	Genetic Variation	[466]
ST6GAL1	OT7US3NO	Limited	Biomarker	[453]
ST6GALNAC5	OTH91ETM	Limited	Biomarker	[467]
SUGP1	OT7W0EB8	Limited	Genetic Variation	[468]
SUMO4	OT9B447E	Limited	Genetic Variation	[469]
TADA1	OTV9RKSL	Limited	Biomarker	[470]
TBPL1	OT4I143E	Limited	Biomarker	[471]
TBX5	OT70PISV	Limited	Altered Expression	[472]
TCN2	OT41D0L3	Limited	Genetic Variation	[473]
TCP1	OT1MGUX9	Limited	Biomarker	[474]
TES	OTL8PP6V	Limited	Altered Expression	[475]
TFAP2B	OTR1T8E9	Limited	Altered Expression	[476]
TFEC	OTUST8MR	Limited	Biomarker	[113]
TGFBRAP1	OT80QNR5	Limited	Genetic Variation	[363]
TIMP4	OT8A68SW	Limited	Genetic Variation	[477]
TLL1	OTK9NM7G	Limited	Genetic Variation	[478]
TMEM132A	OTNUI7O1	Limited	Altered Expression	[479]
TMEM170A	OT65DTBD	Limited	Genetic Variation	[355]
TNIP1	OTRAOTEW	Limited	Genetic Variation	[431]
TNNT1	OT8PBOAR	Limited	Genetic Variation	[480]
TRAF5	OTSBTLO0	Limited	Altered Expression	[481]
TRIB3	OTG5OS7X	Limited	Genetic Variation	[482]
ACAT2	OTZ092ZJ	Disputed	Genetic Variation	[143]
ANGPTL2	OTB6JG41	Disputed	Posttranslational Modification	[483]
APOD	OTT77XW8	Disputed	Biomarker	[484]
CFAP97	OT0RSQO4	Disputed	Altered Expression	[485]
CHRNA3	OTCZQY1U	Disputed	Genetic Variation	[486]
COG2	OTKQH4N4	Disputed	Biomarker	[487]
DHX40	OTOL02QN	Disputed	Biomarker	[140]
EFNA5	OTOH4DRR	Disputed	Biomarker	[138]
ERLIN1	OTUOOODY	Disputed	Genetic Variation	[135]
FASTK	OTTHFZMP	Disputed	Altered Expression	[488]
FETUB	OT7V07NI	Disputed	Biomarker	[489]
MAP1LC3A	OTPMGIU4	Disputed	Biomarker	[490]
MCIDAS	OTK1JVAH	Disputed	Biomarker	[491]
MYOCD	OTSJNHTH	Disputed	Biomarker	[492]
OXCT1	OT536PE7	Disputed	Genetic Variation	[493]
PPP3R1	OTGQNFJQ	Disputed	Genetic Variation	[494]
PSMD4	OTH1VZTM	Disputed	Biomarker	[138]
RFX1	OTZUDMPR	Disputed	Altered Expression	[495]
SOSTDC1	OTAKDNSM	Disputed	Genetic Variation	[496]
ADA2	OTGCV24S	moderate	Genetic Variation	[497]
ANKRD13B	OTJMS7MX	moderate	Genetic Variation	[61]
APH1B	OTQHPTGC	moderate	Genetic Variation	[498]
AQP5	OT77GBY8	moderate	Altered Expression	[499]
ARHGAP15	OT9CKHDC	moderate	Genetic Variation	[61]
ARHGAP26	OTNGQU7A	moderate	Genetic Variation	[61]
ARHGAP4	OTXV053R	moderate	Biomarker	[500]
ARHGAP42	OTIDSJMK	moderate	Genetic Variation	[61]
ARHGEF12	OTM2D3LT	moderate	Genetic Variation	[163]
ARID4A	OT1XKBZ0	moderate	Genetic Variation	[61]
ARL2BP	OT7REEDA	moderate	Genetic Variation	[501]
ASZ1	OTLM93UO	moderate	Genetic Variation	[61]
ATAD1	OTJ02XFL	moderate	Genetic Variation	[502]
ATP1B1	OTTO6ZP4	moderate	Genetic Variation	[61]
ATP4B	OTIP2EYJ	moderate	Biomarker	[161]
ATPAF2	OTOMEQX6	moderate	Genetic Variation	[151]
ATXN2L	OTP5M3R9	moderate	Altered Expression	[503]
B4GALNT2	OT85V4QV	moderate	Genetic Variation	[61]
BCAP29	OTLUBG86	moderate	Genetic Variation	[61]
BCAS3	OTDVAX6B	moderate	Genetic Variation	[61]
BMPR1B	OTGFN0OD	moderate	Genetic Variation	[61]
BRAP	OTB7BAFQ	moderate	Biomarker	[504]
BSND	OTYWZWPD	moderate	Genetic Variation	[501]
C2	OTHMF4YM	moderate	Genetic Variation	[61]
CAPN10	OTS9LJW4	moderate	Biomarker	[505]
CARF	OTWE0T6Q	moderate	Genetic Variation	[158]
CCDC97	OTZSX6TF	moderate	Genetic Variation	[61]
CCM2	OT2I5DOW	moderate	Genetic Variation	[61]
CD300LF	OTQWJGSR	moderate	Genetic Variation	[61]
CENPO	OTXAH83Y	moderate	Genetic Variation	[61]
CHD1L	OT7CZK7C	moderate	Altered Expression	[506]
COG5	OTZEG7K0	moderate	Genetic Variation	[158]
CORO1C	OTXDF9T3	moderate	Genetic Variation	[152]
CORO6	OT9TFSVB	moderate	Genetic Variation	[61]
CPQ	OTTNZNLD	moderate	Biomarker	[500]
CST3	OTNZ6AO4	moderate	Biomarker	[507]
CWF19L2	OT08RTB4	moderate	Genetic Variation	[61]
DAB1	OTPL9MA3	moderate	Genetic Variation	[508]
DECR1	OTCDIR6X	moderate	Biomarker	[509]
DHX38	OTBVB3W5	moderate	Genetic Variation	[61]
DHX58	OT19BYB1	moderate	Genetic Variation	[61]
DOK3	OT842U3C	moderate	Genetic Variation	[61]
DRC3	OTOV0W5A	moderate	Genetic Variation	[151]
EARS2	OTNCJKY7	moderate	Biomarker	[510]
EHBP1L1	OTZMO30X	moderate	Genetic Variation	[61]
EHD3	OTOKC2G5	moderate	Genetic Variation	[511]
ELL	OTCBN5LF	moderate	Genetic Variation	[61]
EML1	OTOP2E01	moderate	Genetic Variation	[61]
EPRS1	OTXK0FLB	moderate	Genetic Variation	[512]
FBF1	OTKA7EZI	moderate	Genetic Variation	[61]
FBN1	OTYCJT63	moderate	Biomarker	[513]
FBRSL1	OT4BPXGG	moderate	Genetic Variation	[152]
FGD5	OT5VIRP2	moderate	Genetic Variation	[61]
FGD6	OTI0T62C	moderate	Genetic Variation	[61]
FHL5	OT6C00Z1	moderate	Genetic Variation	[61]
FNDC3B	OTBILGDR	moderate	Genetic Variation	[61]
FOXA3	OTRGT2OT	moderate	Genetic Variation	[61]
GOSR2	OTYHIYN2	moderate	Genetic Variation	[61]
GPR149	OTN36PTI	moderate	Genetic Variation	[61]
HEATR6	OTD3MYS0	moderate	Genetic Variation	[514]
HIVEP2	OTVOMCW4	moderate	Genetic Variation	[61]
HNRNPM	OTFU3OEZ	moderate	Genetic Variation	[61]
HS3ST1	OT5DVN9P	moderate	SusceptibilityMutation	[515]
IGF2BP1	OT9G360P	moderate	Genetic Variation	[158]
ILRUN	OTE8FHQD	moderate	Genetic Variation	[61]
INSIG1	OTZF5X1D	moderate	Genetic Variation	[516]
KANK2	OT3SZIWM	moderate	Genetic Variation	[61]
KAT2A	OTN0W2SW	moderate	Genetic Variation	[61]
KCNAB1	OT25GJE9	moderate	Genetic Variation	[128]
KDELR2	OT9QW7Q0	moderate	Genetic Variation	[61]
KIAA1217	OTRMK3PU	moderate	Genetic Variation	[61]
KSR2	OTSMUL59	moderate	Genetic Variation	[517]
LIPC	OTZY5SC9	moderate	Altered Expression	[518]
LPCAT3	OTWI96P4	moderate	Biomarker	[519]
LTBP1	OTR7Q75L	moderate	Altered Expression	[520]
MAP1S	OT5WUD4C	moderate	Genetic Variation	[61]
MARK4	OT6Z2TGV	moderate	Genetic Variation	[61]
MAST4	OT3LOE2J	moderate	Genetic Variation	[61]
MCF2L	OTEURA8N	moderate	Genetic Variation	[61]
MORF4L1	OTEA6FYJ	moderate	Genetic Variation	[61]
MPZL2	OTKFNDUI	moderate	Genetic Variation	[173]
MSL2	OTVPQYBG	moderate	Genetic Variation	[61]
MYH11	OTVNVWY3	moderate	Genetic Variation	[61]
MYO9B	OTQ94R5K	moderate	Genetic Variation	[61]
N4BP2L2	OTV2F04G	moderate	Genetic Variation	[61]
NAA25	OTS3QVF1	moderate	Genetic Variation	[163]
NBEAL1	OTLJ11N3	moderate	Genetic Variation	[61]
NCOA6	OTOMIGTV	moderate	Genetic Variation	[61]
NDUFA12	OTCD6I5M	moderate	Genetic Variation	[61]
NME7	OTYMBK3Q	moderate	Genetic Variation	[61]
NOA1	OT9GTOAC	moderate	Genetic Variation	[61]
NUP210	OT3BLQ9M	moderate	Genetic Variation	[165]
PALLD	OTZ2MUJZ	moderate	Genetic Variation	[61]
PARL	OT7DMHSA	moderate	Genetic Variation	[521]
PARP12	OTCQTYIO	moderate	Genetic Variation	[61]
PCNX3	OTOM3GHH	moderate	Genetic Variation	[61]
PDLIM5	OTLQVV22	moderate	Genetic Variation	[61]
PDS5B	OT3U3X8Z	moderate	Genetic Variation	[61]
PLCG2	OTGVC9MY	moderate	Genetic Variation	[61]
PLCL1	OTJL2C79	moderate	Genetic Variation	[128]
PLEKHA7	OTNUMAZ0	moderate	Genetic Variation	[61]
PLEKHG1	OTDVYW2F	moderate	Genetic Variation	[61]
PMAIP1	OTXEE550	moderate	Genetic Variation	[522]
PRB2	OTAD4JZ0	moderate	Genetic Variation	[523]
PRDM6	OTKY12D9	moderate	Genetic Variation	[61]
QRICH1	OTPVAX04	moderate	Genetic Variation	[61]
R3HDM2	OTMJ3S6J	moderate	Genetic Variation	[61]
RAB37	OTRL8IUO	moderate	Genetic Variation	[61]
RAMP2	OTGQXLH5	moderate	Altered Expression	[148]
RAMP3	OTX6XLLM	moderate	Altered Expression	[148]
RASGEF1B	OT56BBU0	moderate	Genetic Variation	[61]
RERE	OT3G4GBZ	moderate	Genetic Variation	[145]
REST	OTLL92LQ	moderate	Genetic Variation	[61]
RETN	OTW5Z1NH	moderate	Biomarker	[524]
RPA1	OT76POLP	moderate	Genetic Variation	[525]
RRBP1	OT4ZTPTM	moderate	Genetic Variation	[61]
RRP1B	OTHDRVML	moderate	Genetic Variation	[61]
SACM1L	OT6ORKTD	moderate	Genetic Variation	[526]
SARS1	OTFKXQ1O	moderate	Genetic Variation	[151]
SCAF11	OTX59D0X	moderate	Genetic Variation	[61]
SCG2	OTXWUQQL	moderate	Biomarker	[527]
SELENOI	OTX2A47A	moderate	Genetic Variation	[61]
SELENOS	OTUEWIU9	moderate	Genetic Variation	[528]
SEMA5A	OTUOIOJV	moderate	Genetic Variation	[61]
SERPINA2	OT7UW9HA	moderate	Genetic Variation	[61]
SHOC1	OTP51XIP	moderate	Genetic Variation	[128]
SHROOM3	OTQKC5X2	moderate	Genetic Variation	[61]
SMG6	OTRCEJQL	moderate	Genetic Variation	[61]
SOX6	OTT0W0LE	moderate	Genetic Variation	[61]
SPAG11A	OTNQ9UB0	moderate	Genetic Variation	[170]
SRFBP1	OTI8518R	moderate	Genetic Variation	[61]
ST3GAL4	OTNENJZQ	moderate	Genetic Variation	[61]
STAG1	OT564IX4	moderate	Genetic Variation	[61]
STOML1	OTSIO2QA	moderate	Genetic Variation	[61]
SUSD2	OTSJTAZP	moderate	Genetic Variation	[61]
SWAP70	OTPHT2QD	moderate	Genetic Variation	[61]
TADA2A	OTXUMEL9	moderate	Genetic Variation	[497]
TBL1Y	OTA0F7TM	moderate	Genetic Variation	[529]
TBX20	OTMPU2XQ	moderate	Genetic Variation	[61]
TDRKH	OTV21BN1	moderate	Genetic Variation	[61]
TENT5A	OTSYF511	moderate	Genetic Variation	[163]
THADA	OTYZQX0F	moderate	Genetic Variation	[61]
TMEM106B	OTUWA6NW	moderate	Genetic Variation	[61]
TMEM163	OTCT1Y1L	moderate	Genetic Variation	[530]
TNS1	OTZ8S1PL	moderate	Genetic Variation	[61]
TPTE2	OTR3K733	moderate	Genetic Variation	[530]
TRIM5	OTMZH7EJ	moderate	Genetic Variation	[61]
TSPAN14	OT29167O	moderate	Genetic Variation	[61]
TSPAN9	OT3DI3NH	moderate	Genetic Variation	[61]
ABHD2	OTCRUOCS	Strong	Genetic Variation	[249]
ACADS	OTGFANYQ	Strong	Biomarker	[531]
ACCS	OTHIHI9D	Strong	Biomarker	[324]
ACP1	OTJ9CKLU	Strong	Genetic Variation	[532]
ACTA2	OTEDLG8E	Strong	Genetic Variation	[533]
ADAMTS7	OTVKZ1DV	Strong	Genetic Variation	[534]
ADIPOR1	OT65ZFZN	Strong	Genetic Variation	[535]
ADTRP	OTFI2BQX	Strong	Biomarker	[536]
AFG3L2	OTRPMAUX	Strong	Posttranslational Modification	[537]
AKAP13	OTOZAR14	Strong	Genetic Variation	[61]
AMPD1	OTU17BCI	Strong	Genetic Variation	[538]
ANKS1A	OTYZP3MP	Strong	Genetic Variation	[165]
AP1S2	OTZHJFYI	Strong	Biomarker	[539]
ARHGEF26	OTX0U8PX	Strong	Genetic Variation	[61]
ARID5B	OTUQ4CQY	Strong	Genetic Variation	[540]
ARL15	OT00YSWZ	Strong	Genetic Variation	[61]
ARPP21	OTWXZN5I	Strong	Biomarker	[541]
BCL3	OT1M5B95	Strong	Genetic Variation	[542]
BGLAP	OTK1YLWQ	Strong	Biomarker	[543]
BID	OTOSHSHU	Strong	Genetic Variation	[544]
BMPR1A	OTQOA4ZH	Strong	Biomarker	[545]
BTBD8	OT3A3RD7	Strong	Genetic Variation	[546]
BTNL2	OTTTEMZA	Strong	Biomarker	[547]
BUD13	OTXG6MX5	Strong	Genetic Variation	[548]
C16orf82	OT77Z5Y5	Strong	Genetic Variation	[480]
C1QTNF12	OTFAIQHR	Strong	Altered Expression	[549]
C5AR2	OTP1Q82J	Strong	Genetic Variation	[550]
CACUL1	OT6P1ZVP	Strong	Genetic Variation	[551]
CAMK2N1	OTKCR5XL	Strong	Altered Expression	[552]
CAPG	OTJ86KI6	Strong	Biomarker	[553]
CASP8AP2	OTTWT68S	Strong	Biomarker	[554]
CASQ2	OT09MNQ8	Strong	Genetic Variation	[555]
CASZ1	OTWJ2OR8	Strong	Biomarker	[312]
CAV2	OT1FGRQX	Strong	Altered Expression	[556]
CCDC92	OT1YHLOR	Strong	Genetic Variation	[61]
CCHCR1	OT22C116	Strong	Biomarker	[557]
CDH13	OTD2CYM5	Strong	Genetic Variation	[61]
CDH4	OT8LH3HN	Strong	Biomarker	[558]
CDKN2B	OTAG24N1	Strong	Genetic Variation	[559]
CELSR2	OTON6JSZ	Strong	Genetic Variation	[61]
CFDP1	OTXY7J96	Strong	Genetic Variation	[457]
CHI3L1	OT2Z7VJH	Strong	Biomarker	[560]
CHST9	OT1DEZRM	Strong	Genetic Variation	[561]
CLEC1B	OTO38TRG	Strong	Biomarker	[562]
CNNM2	OTZHO8WU	Strong	Genetic Variation	[61]
COL4A1	OTL6D1YE	Strong	Genetic Variation	[61]
COX10	OTCYIS0L	Strong	Biomarker	[563]
COX8A	OTU0NR39	Strong	Altered Expression	[564]
CPA3	OTOK8M0V	Strong	Biomarker	[204]
CPN2	OTYOYP14	Strong	Biomarker	[11]
CPNE3	OTCR3WG2	Strong	Altered Expression	[565]
CTRB1	OTFFF738	Strong	Genetic Variation	[566]
CTRL	OTB6NA5O	Strong	Biomarker	[567]
CXCL5	OTZOUPCA	Strong	Altered Expression	[568]
DAB2IP	OTF456VC	Strong	Genetic Variation	[61]
DBP	OTE0W7LN	Strong	Biomarker	[569]
DDAH2	OT8Q40G2	Strong	Genetic Variation	[570]
DIO2	OTGPNSLH	Strong	Genetic Variation	[211]
DOCK7	OTINNVQV	Strong	Genetic Variation	[571]
EBF1	OTZ61YYH	Strong	Genetic Variation	[572]
ERCC2	OT1C8HQ4	Strong	Genetic Variation	[302]
ERFE	OTSES1HA	Strong	Biomarker	[573]
ESM1	OT331Y8V	Strong	Altered Expression	[574]
FCGR3B	OTSLSPZG	Strong	Biomarker	[221]
FCN1	OTK6ZHXH	Strong	Biomarker	[272]
FLAD1	OTY8R02L	Strong	Genetic Variation	[255]
GAL3ST1	OTSFFZRD	Strong	Biomarker	[312]
GALNT2	OTZZ5386	Strong	Genetic Variation	[61]
GALNT4	OT6WKC13	Strong	Genetic Variation	[575]
GC	OTWS63BY	Strong	Genetic Variation	[576]
GCA	OTAJ7ZHG	Strong	Biomarker	[225]
GCKR	OTSIWXGG	Strong	Genetic Variation	[577]
GIGYF2	OTFNVEJ4	Strong	Genetic Variation	[61]
GMCL1	OTRZHUFV	Strong	Biomarker	[225]
GNB3	OTA6HYBA	Strong	Genetic Variation	[578]
GPR162	OTK4LT3K	Strong	Biomarker	[579]
GSTK1	OTDNGWAF	Strong	Genetic Variation	[313]
HHIPL1	OT3GMU2X	Strong	Biomarker	[580]
HSPA2	OTSDET7B	Strong	Genetic Variation	[581]
HSPH1	OTVRR73T	Strong	Biomarker	[195]
IGFBP4	OT2HZRBD	Strong	Biomarker	[582]
IL17RA	OTVVI8ER	Strong	Biomarker	[583]
ISYNA1	OT49ONSE	Strong	Biomarker	[142]
ITGA2B	OT4Y17PY	Strong	Genetic Variation	[584]
JPH3	OTHTJO2I	Strong	Genetic Variation	[585]
KCNE2	OTUO214Y	Strong	Biomarker	[522]
KCNJ13	OTG1CNND	Strong	Genetic Variation	[61]
KCNK5	OT68V64E	Strong	Genetic Variation	[61]
KDM5D	OTEKG0KD	Strong	Biomarker	[586]
KL	OTD4VWU6	Strong	Biomarker	[587]
KLF14	OT8BXLBS	Strong	Biomarker	[588]
KLF15	OTGMQMVR	Strong	Altered Expression	[589]
KLF2	OTIP1UFX	Strong	Genetic Variation	[590]
KLLN	OTV3FPH0	Strong	Biomarker	[591]
LGALS3BP	OT9AGQKH	Strong	Biomarker	[592]
LMOD1	OTZ2MEMG	Strong	Genetic Variation	[61]
LRP8	OTZ71YV2	Strong	Genetic Variation	[593]
MAP3K7CL	OT9J7RLC	Strong	Genetic Variation	[61]
MARCHF1	OTI2EYO6	Strong	Biomarker	[594]
MEFV	OTRJ6S6K	Strong	Altered Expression	[31]
MEGF8	OT5G38CH	Strong	Biomarker	[595]
METRN	OTI2645G	Strong	Altered Expression	[596]
METRNL	OTB0DDL0	Strong	Altered Expression	[596]
MLKL	OTDSLC81	Strong	Biomarker	[597]
MLXIPL	OTR9MLLW	Strong	Genetic Variation	[598]
MMP23B	OT2OR6TS	Strong	Biomarker	[599]
MMRN1	OT7ZNYHT	Strong	Genetic Variation	[600]
MPRIP	OT5FV5NS	Strong	Altered Expression	[601]
MRTFA	OTCVXASM	Strong	Genetic Variation	[61]
MTHFD1L	OTV01EFP	Strong	Genetic Variation	[602]
MYO1F	OTOAV4AR	Strong	Biomarker	[272]
NBL1	OTT37U4O	Strong	Altered Expression	[603]
NECTIN2	OTIE0W6O	Strong	Biomarker	[542]
NFKBIZ	OTU728KS	Strong	Genetic Variation	[90]
NLN	OTFRITPU	Strong	Altered Expression	[604]
NLRP12	OTGR132Z	Strong	Genetic Variation	[605]
NOS1AP	OTDFOBRU	Strong	Genetic Variation	[606]
NPC1	OTRIPICX	Strong	Genetic Variation	[61]
NPPA	OTMQNTNX	Strong	Genetic Variation	[258]
NUS1	OT4DQ82L	Strong	Altered Expression	[182]
OGN	OTKP5S4L	Strong	Altered Expression	[607]
OPN4	OT1LZ7TS	Strong	Altered Expression	[604]
ORM2	OTRJGZP8	Strong	Biomarker	[11]
PAPPA	OTTTG9PG	Strong	Genetic Variation	[608]
PEAR1	OT2XLTB2	Strong	Genetic Variation	[609]
PHACTR1	OTAMPX9V	Strong	Genetic Variation	[610]
PIK3C2A	OTFBU4GD	Strong	Altered Expression	[611]
PKP2	OTJOVF68	Strong	Biomarker	[612]
PLA2G10	OTRZ2L5A	Strong	Altered Expression	[613]
PLA2G15	OT6VJTPA	Strong	Biomarker	[324]
PLB1	OTZ6TTYV	Strong	Biomarker	[614]
POC1A	OTXAG4PL	Strong	Genetic Variation	[615]
POU2F3	OTIOOJWD	Strong	Genetic Variation	[616]
PPARGC1A	OTHCDQ22	Strong	Altered Expression	[617]
PPIC	OTY5Q42N	Strong	Altered Expression	[618]
PQBP1	OTXCBEAH	Strong	Biomarker	[619]
PRDM16	OT0BGA27	Strong	Genetic Variation	[61]
PRKAB2	OTLVN68B	Strong	Biomarker	[620]
PRKX	OTDAC6Z0	Strong	Genetic Variation	[195]
PROCR	OTRHED17	Strong	Genetic Variation	[61]
PSRC1	OT7MDJMN	Strong	Genetic Variation	[621]
RAPSN	OTGMSWDQ	Strong	Genetic Variation	[255]
RARRES2	OT1BJE8K	Strong	Genetic Variation	[622]
RGN	OTD04KB1	Strong	Biomarker	[619]
RGS5	OTUY0Q2I	Strong	Genetic Variation	[623]
RLN1	OTL6QNHG	Strong	Altered Expression	[624]
RNLS	OTVP2WJM	Strong	Genetic Variation	[625]
RRAD	OTW2O4GD	Strong	Genetic Variation	[626]
RYR2	OT0PF19E	Strong	Genetic Variation	[555]
RYR3	OT4EHIP4	Strong	Genetic Variation	[627]
SCML4	OTSZJST3	Strong	Genetic Variation	[508]
SELENBP1	OT3NZNTR	Strong	Biomarker	[557]
SEMA3F	OTQFMS8S	Strong	Altered Expression	[628]
SERPINB2	OT72QLZB	Strong	Genetic Variation	[629]
SERPINE2	OTYF5340	Strong	Biomarker	[630]
SFRP5	OTLCVVSH	Strong	Altered Expression	[631]
SHBG	OTPWU5IW	Strong	Biomarker	[557]
SP6	OTRAB1PN	Strong	Biomarker	[588]
SPAAR	OTWXG2R8	Strong	Altered Expression	[632]
SRF	OTW18FQN	Strong	Biomarker	[492]
STARD7	OTDUZ296	Strong	Biomarker	[183]
STN1	OT8UWRA3	Strong	Genetic Variation	[61]
SVEP1	OTOBICRD	Strong	Genetic Variation	[61]
TFR2	OTMYCCEO	Strong	Genetic Variation	[633]
THAP5	OT6ZMFYF	Strong	Biomarker	[634]
THSD7A	OT7249HH	Strong	Genetic Variation	[508]
TMEM54	OTPQEFR0	Strong	Genetic Variation	[551]
TNFAIP6	OT1SLUZH	Strong	Biomarker	[635]
TNFRSF6B	OTKAN9G7	Strong	Biomarker	[636]
TOMM40	OTZDQ29F	Strong	Genetic Variation	[637]
TREML4	OT2VLMTL	Strong	Biomarker	[638]
TRIB1	OTPEO17G	Strong	Altered Expression	[639]
TRPS1	OT7XPPEL	Strong	Genetic Variation	[639]
AP2A2	OTD1UGUN	Definitive	Genetic Variation	[640]
ARIH1	OTO3XDR2	Definitive	Biomarker	[641]
C1QTNF5	OTLKU5I2	Definitive	Altered Expression	[642]
CAPN3	OTCHG3YK	Definitive	Genetic Variation	[643]
CCS	OTXHT3QO	Definitive	Biomarker	[644]
CKMT2	OT1KNPI1	Definitive	Biomarker	[645]
CPT1A	OTI862QH	Definitive	Biomarker	[168]
CRISPLD1	OT38HXJP	Definitive	Genetic Variation	[646]
DEFA1	OT5N1B9B	Definitive	Biomarker	[647]
DEFA3	OTO3N8E1	Definitive	Biomarker	[647]
EIF4A3	OTYYFE7K	Definitive	Altered Expression	[648]
FADS3	OT9RVXGE	Definitive	Genetic Variation	[649]
GDF10	OTEVXGJ7	Definitive	Genetic Variation	[650]
GOLGA6A	OTHU9MRX	Definitive	Genetic Variation	[213]
HABP2	OTAUIPW0	Definitive	Biomarker	[651]
HDLBP	OTKDEEYX	Definitive	Biomarker	[652]
HPR	OTXSC9UB	Definitive	Genetic Variation	[643]
HRG	OTPLUFOG	Definitive	Biomarker	[653]
INPP5K	OTQFLQKA	Definitive	Biomarker	[415]
INTS4	OT5JQ913	Definitive	Biomarker	[654]
ITSN1	OT8YF3S5	Definitive	Altered Expression	[655]
LRG1	OTLD0KWA	Definitive	Biomarker	[653]
LRRC3B	OT9VDGPR	Definitive	Biomarker	[645]
MACIR	OTPSW8Y8	Definitive	Genetic Variation	[656]
MFRP	OTHY9ZA5	Definitive	Altered Expression	[642]
MRPS6	OTKFY73U	Definitive	Biomarker	[657]
MTHFD2	OT1LQSGX	Definitive	Genetic Variation	[658]
PPP4C	OT4B0TNV	Definitive	Biomarker	[306]
RASGRF2	OT67DAGF	Definitive	Biomarker	[645]
RCBTB1	OTAYELI8	Definitive	Genetic Variation	[213]
RNF213	OT4OVE9O	Definitive	Genetic Variation	[659]
RPS3A	OTUEP7CL	Definitive	Biomarker	[660]
RTCA	OTSJRVTD	Definitive	Biomarker	[661]
SELENOP	OT02B8IR	Definitive	Altered Expression	[662]
SIPA1	OTXY5RXC	Definitive	Biomarker	[663]
SIRT4	OT5S0J23	Definitive	Altered Expression	[664]
SIX5	OTT1I9WY	Definitive	Genetic Variation	[643]
SORBS3	OTVEUODC	Definitive	Altered Expression	[665]

References

• [1] Probucol FDA Label
• [2] Sertraline FDA Label
• [3] Simvastatin FDA Label
• [4] ClinicalTrials.gov (NCT01126073) A Double Blind, Randomized Study to Compare Influence of Niacin/Laropiprant on Functional and Morphological Characteristics of Arterial Wall and Parameters of Inflammation in Subjects With Coronary Heart Disease Already Treated With a Statin in Miran Sebestjen, University Medical Centre Ljubljana.
• [5] Heparin FDA Label
• [6] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [7] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4923).
• [8] ClinicalTrials.gov (NCT04610892) A Phase IIB, Randomized, Double Blinded, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of MEDI6570 in Participants With a Prior Myocardial Infarction and Persistent Inflammation. U.S.National Institutes of Health.
• [9] Relationship between circulating levels of angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS axis and coronary heart disease.Heart Vessels. 2020 Feb;35(2):153-161. doi: 10.1007/s00380-019-01478-y. Epub 2019 Jul 29.
• [10] ACR Appropriateness Criteria() Chronic Chest Pain-Noncardiac Etiology Unlikely-Low to Intermediate Probability of Coronary Artery Disease.J Am Coll Radiol. 2018 Nov;15(11S):S283-S290. doi: 10.1016/j.jacr.2018.09.021.
• [11] Myocardial Injury Is Distinguished from Stable Angina by a Set of Candidate Plasma Biomarkers Identified Using iTRAQ/MRM-Based Approach.J Proteome Res. 2018 Jan 5;17(1):499-515. doi: 10.1021/acs.jproteome.7b00651. Epub 2017 Nov 7.
• [12] Intriguing Roles for Endothelial ADAM10/Notch Signaling in the Development of Organ-Specific Vascular Beds.Physiol Rev. 2018 Oct 1;98(4):2025-2061. doi: 10.1152/physrev.00029.2017.
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• [29] IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction.Front Immunol. 2018 Sep 12;9:2035. doi: 10.3389/fimmu.2018.02035. eCollection 2018.
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