General Information of Drug Combination (ID: DCJ6HGL)

Drug Combination Name
THAPSIGARGIN Lenvatinib
Indication
Disease Entry Status REF
Ewing sarcoma Investigative [1]
Component Drugs THAPSIGARGIN   DMDMQIE Lenvatinib   DMB1IU4
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL
High-throughput Screening Result Testing Cell Line: TC-71
Zero Interaction Potency (ZIP) Score: 22.109
Bliss Independence Score: 23.652
Loewe Additivity Score: 0.049
LHighest Single Agent (HSA) Score: 1.668

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
THAPSIGARGIN Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Sarcoplasmic/endoplasmic reticulum calcium ATPase (ATP2A) TTZVSJ2 NOUNIPROTAC Inhibitor [14]
------------------------------------------------------------------------------------
THAPSIGARGIN Interacts with 1041 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Decreases Expression [15]
Serine/threonine-protein kinase PLK4 (PLK4) OTV8KZDZ PLK4_HUMAN Increases Expression [7]
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CACNA1A) OTY08SIX CAC1A_HUMAN Increases Expression [7]
Dihydropyrimidinase-related protein 4 (DPYSL4) OT3SBS2S DPYL4_HUMAN Increases Expression [7]
BET1 homolog (BET1) OTGX2557 BET1_HUMAN Decreases Expression [7]
Intermediate conductance calcium-activated potassium channel protein 4 (KCNN4) OTQKQ346 KCNN4_HUMAN Increases Expression [7]
Leucine-rich repeat transmembrane protein FLRT2 (FLRT2) OTGD8TID FLRT2_HUMAN Decreases Expression [7]
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) OTXP7MXN TIM44_HUMAN Decreases Expression [7]
Golgi SNAP receptor complex member 1 (GOSR1) OTX8TMVU GOSR1_HUMAN Decreases Expression [7]
Glutathione reductase, mitochondrial (GSR) OTM2TUYM GSHR_HUMAN Decreases Expression [7]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Decreases Expression [7]
Plasminogen activator inhibitor 2 (SERPINB2) OT72QLZB PAI2_HUMAN Increases Expression [7]
Endoplasmin (HSP90B1) OT02XLBR ENPL_HUMAN Decreases Expression [7]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Expression [7]
Peroxiredoxin-5, mitochondrial (PRDX5) OTUEKZ18 PRDX5_HUMAN Decreases Expression [7]
Dual specificity protein kinase TTK (TTK) OTBY1Z5H TTK_HUMAN Increases Expression [7]
DNA replication licensing factor MCM7 (MCM7) OT6FXC6K MCM7_HUMAN Increases Expression [7]
Centromere protein F (CENPF) OT7AG0SW CENPF_HUMAN Increases Expression [7]
ETS domain-containing transcription factor ERF (ERF) OTGTA85X ERF_HUMAN Increases Expression [7]
Hepatoma-derived growth factor (HDGF) OT16PTBC HDGF_HUMAN Increases Expression [7]
Serine/threonine-protein kinase PLK1 (PLK1) OTRZX45T PLK1_HUMAN Increases Expression [7]
Protein max (MAX) OTKZ0YKM MAX_HUMAN Decreases Expression [7]
Cytochrome P450 4F3 (CYP4F3) OTYNSQAM CP4F3_HUMAN Decreases Expression [7]
Neuroblast differentiation-associated protein AHNAK (AHNAK) OT6KH1WG AHNK_HUMAN Increases Expression [7]
Cell division cycle protein 20 homolog (CDC20) OTCOEZRV CDC20_HUMAN Increases Expression [7]
Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5) OT6T408U MP2K5_HUMAN Decreases Expression [7]
Scavenger receptor class A member 3 (SCARA3) OT46I38Y SCAR3_HUMAN Increases Expression [7]
Sideroflexin-4 (SFXN4) OT2KLSS9 SFXN4_HUMAN Decreases Expression [7]
V-type proton ATPase subunit d 2 (ATP6V0D2) OTMOZJO0 VA0D2_HUMAN Decreases Expression [7]
Serine/threonine-protein kinase 32A (STK32A) OTONYLYO ST32A_HUMAN Decreases Expression [7]
Fibroblast growth factor 13 (FGF13) OTHNNVSG FGF13_HUMAN Decreases Expression [7]
BTB/POZ domain-containing protein KCTD12 (KCTD12) OTPYKT4Z KCD12_HUMAN Increases Expression [7]
Cation channel sperm-associated protein 2 (CATSPER2) OT1841AS CTSR2_HUMAN Decreases Expression [7]
Kinesin-like protein KIF20B (KIF20B) OTS68AHH KI20B_HUMAN Increases Expression [7]
Sodium channel protein type 2 subunit alpha (SCN2A) OTUSYE4Z SCN2A_HUMAN Increases Expression [7]
Protein S100-A13 (S100A13) OT582SUS S10AD_HUMAN Increases Expression [7]
Kinesin-like protein KIF2C (KIF2C) OTJ8G3NP KIF2C_HUMAN Increases Expression [7]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1) OTJGE772 CHAC1_HUMAN Decreases Expression [7]
Kinesin-like protein KIF15 (KIF15) OTJRJEXL KIF15_HUMAN Increases Expression [7]
DnaJ homolog subfamily B member 11 (DNAJB11) OTDDK2SY DJB11_HUMAN Decreases Expression [7]
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) OTVIHD77 MACF1_HUMAN Increases Expression [7]
C-type lectin domain family 11 member A (CLEC11A) OT9KBH7C CLC11_HUMAN Increases Expression [7]
Period circadian protein homolog 1 (PER1) OTVQF3WX PER1_HUMAN Increases Expression [16]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Increases Expression [16]
Glycoprotein hormones alpha chain (CGA) OT00U3Y3 GLHA_HUMAN Increases Expression [16]
Metallothionein-1A (MT1A) OTKBH52X MT1A_HUMAN Increases Expression [16]
Inhibin beta A chain (INHBA) OTSP64PQ INHBA_HUMAN Increases Expression [16]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Increases Expression [16]
Nuclear receptor subfamily 4 group A member 2 (NR4A2) OT3F9IR2 NR4A2_HUMAN Increases Expression [16]
Protein FosB (FOSB) OTW6C05J FOSB_HUMAN Increases Expression [16]
GTP-binding protein GEM (GEM) OT6SK8ZV GEM_HUMAN Increases Expression [16]
PLAC8-like protein 1 (PLAC8L1) OTHF4LKX PL8L1_HUMAN Increases Expression [8]
Protein tyrosine phosphatase domain-containing protein 1 (PTPDC1) OTTM4N1J PTPC1_HUMAN Increases Expression [8]
Mapk-regulated corepressor-interacting protein 1 (MCRIP1) OTY3EW73 MCRI1_HUMAN Decreases Expression [8]
Deoxyribonuclease-2-alpha (DNASE2) OT6RC1BL DNS2A_HUMAN Increases Expression [8]
Serine/threonine-protein kinase Sgk1 (SGK1) OT301T1U SGK1_HUMAN Decreases Expression [8]
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) OT7C68YV BACH_HUMAN Decreases Expression [8]
HCLS1-associated protein X-1 (HAX1) OTOJWV3F HAX1_HUMAN Increases Expression [8]
Potassium channel subfamily K member 1 (KCNK1) OTBXPTKX KCNK1_HUMAN Decreases Expression [8]
Cell division cycle 7-related protein kinase (CDC7) OT5133XY CDC7_HUMAN Decreases Expression [8]
Pyruvate dehydrogenase protein X component, mitochondrial (PDHX) OTG7O271 ODPX_HUMAN Decreases Expression [8]
Homeobox protein Meis1 (MEIS1) OTH9DKAD MEIS1_HUMAN Decreases Expression [8]
Cytochrome c oxidase subunit NDUFA4 (NDUFA4) OTDVH3QG NDUA4_HUMAN Decreases Expression [8]
Membrane-associated phosphatidylinositol transfer protein 1 (PITPNM1) OTIUYAG5 PITM1_HUMAN Increases Expression [8]
Nucleoside diphosphate kinase, mitochondrial (NME4) OT2JTT42 NDKM_HUMAN Decreases Expression [8]
Class E basic helix-loop-helix protein 40 (BHLHE40) OTITX14U BHE40_HUMAN Decreases Expression [8]
Acyl carrier protein, mitochondrial (NDUFAB1) OTF906UR ACPM_HUMAN Decreases Expression [8]
Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1) OTFX1KCG DC1I1_HUMAN Decreases Expression [8]
Ectoderm-neural cortex protein 1 (ENC1) OTJEUB6U ENC1_HUMAN Decreases Expression [8]
Serine/threonine-protein kinase Chk1 (CHEK1) OTTTI622 CHK1_HUMAN Decreases Expression [8]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Increases Expression [8]
Serine/threonine-protein phosphatase with EF-hands 1 (PPEF1) OT3X4HCS PPE1_HUMAN Decreases Expression [8]
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) OTDLYLRZ BCKD_HUMAN Decreases Expression [8]
Tax1-binding protein 3 (TAX1BP3) OTQ6IB4T TX1B3_HUMAN Decreases Expression [8]
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) OTAAS85T TIM23_HUMAN Decreases Expression [8]
Phosphoribosylformylglycinamidine synthase (PFAS) OTCOBYYK PUR4_HUMAN Decreases Expression [8]
Mitochondrial ribonuclease P catalytic subunit (PRORP) OTWIS44P MRPP3_HUMAN Decreases Expression [8]
Actin-related protein 2/3 complex subunit 3 (ARPC3) OTKWVF8P ARPC3_HUMAN Increases Expression [8]
Surfeit locus protein 4 (SURF4) OTCSXJ9C SURF4_HUMAN Increases Expression [8]
Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) OT8L6EGI BCAT2_HUMAN Increases Expression [8]
Insulin-induced gene 1 protein (INSIG1) OTZF5X1D INSI1_HUMAN Decreases Expression [8]
Regulator of G-protein signaling 5 (RGS5) OTUY0Q2I RGS5_HUMAN Decreases Expression [8]
Cytochrome b5 type B (CYB5B) OTONNAV1 CYB5B_HUMAN Decreases Expression [8]
D-3-phosphoglycerate dehydrogenase (PHGDH) OT1LMRTG SERA_HUMAN Increases Expression [8]
Mitogen-activated protein kinase kinase kinase 13 (MAP3K13) OTS93BTX M3K13_HUMAN Decreases Expression [8]
Protein Mis18-beta (OIP5) OTI5C2DE MS18B_HUMAN Decreases Expression [8]
Protein sprouty homolog 2 (SPRY2) OTH0CRCZ SPY2_HUMAN Decreases Expression [8]
Protein regulator of cytokinesis 1 (PRC1) OTHD0XS0 PRC1_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) OTDV12IF NDUB3_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 subunit C1, mitochondrial (NDUFC1) OTJ5TNHB NDUC1_HUMAN Decreases Expression [8]
Lipoyl synthase, mitochondrial (LIAS) OTOSW67J LIAS_HUMAN Increases Expression [8]
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) OT6CLFXB MCAT_HUMAN Increases Expression [8]
Asparagine--tRNA ligase, cytoplasmic (NARS1) OTFS4J1W SYNC_HUMAN Increases Expression [8]
NADH dehydrogenase iron-sulfur protein 5 (NDUFS5) OTF40UYJ NDUS5_HUMAN Decreases Expression [8]
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) OTDX9687 TIM8A_HUMAN Decreases Expression [8]
tRNA wybutosine-synthesizing protein 4 (LCMT2) OT4RUVCM TYW4_HUMAN Decreases Expression [8]
BMP/retinoic acid-inducible neural-specific protein 1 (BRINP1) OTEUVSCP BRNP1_HUMAN Decreases Expression [8]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) OT8KME51 BUB1B_HUMAN Decreases Expression [8]
Receptor activity-modifying protein 1 (RAMP1) OT7UT2XB RAMP1_HUMAN Decreases Expression [8]
Frizzled-7 (FZD7) OTTK3F6E FZD7_HUMAN Decreases Expression [8]
Low-density lipoprotein receptor-related protein 4 (LRP4) OTO4M459 LRP4_HUMAN Decreases Expression [8]
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4) OT4CA13K ATS4_HUMAN Decreases Expression [8]
Liprin-alpha-4 (PPFIA4) OTWXG0DO LIPA4_HUMAN Decreases Expression [8]
Adapter SH3BGRL (SH3BGRL) OTUOCTMT SH3L1_HUMAN Decreases Expression [8]
DNA polymerase theta (POLQ) OTBHK0E6 DPOLQ_HUMAN Decreases Expression [8]
Cell division control protein 45 homolog (CDC45) OT6NNLOD CDC45_HUMAN Decreases Expression [8]
Geminin (GMNN) OTDYKNIY GEMI_HUMAN Decreases Expression [8]
Barrier-to-autointegration factor (BANF1) OTP7Z38L BAF_HUMAN Decreases Expression [8]
Peptide chain release factor 1, mitochondrial (MTRF1) OTRTUUM4 RF1M_HUMAN Increases Expression [8]
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) OT6WZPWV KBL_HUMAN Decreases Expression [8]
Ribonuclease H2 subunit A (RNASEH2A) OT8G3G7K RNH2A_HUMAN Decreases Expression [8]
Ribonuclease P protein subunit p20 (POP7) OTKC7SG5 POP7_HUMAN Decreases Expression [8]
Protein SCO1 homolog, mitochondrial (SCO1) OTC45UGB SCO1_HUMAN Decreases Expression [8]
Short-chain dehydrogenase/reductase 3 (DHRS3) OTSK1DTP DHRS3_HUMAN Increases Expression [8]
Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2) OTR99SJ8 CDKA2_HUMAN Increases Expression [8]
Stanniocalcin-2 (STC2) OT86YP8G STC2_HUMAN Increases Expression [8]
Bestrophin-1 (BEST1) OTWHE1ZC BEST1_HUMAN Increases Expression [8]
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH1) OT1U2GWG DDAH1_HUMAN Decreases Expression [8]
Regulator of G-protein signaling 11 (RGS11) OTIAZ36F RGS11_HUMAN Increases Expression [8]
Slit homolog 2 protein (SLIT2) OTLS2RJ4 SLIT2_HUMAN Decreases Expression [8]
Dickkopf-related protein 1 (DKK1) OTRDLUSP DKK1_HUMAN Decreases Expression [8]
Glutaminase kidney isoform, mitochondrial (GLS) OTGOZG2M GLSK_HUMAN Increases Expression [8]
Protein transport protein Sec31A (SEC31A) OT2U42AC SC31A_HUMAN Increases Expression [8]
Meiotic recombination protein REC8 homolog (REC8) OT6JAVXE REC8_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) OTIXNT91 NDUB6_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) OTXL10N9 NDUA3_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial (NDUFB8) OTW4A4Q0 NDUB8_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 alpha subcomplex subunit 7 (NDUFA7) OT8CV3H5 NDUA7_HUMAN Decreases Expression [8]
Chondroitin sulfate proteoglycan 5 (CSPG5) OTXFEBWR CSPG5_HUMAN Decreases Expression [8]
Mitochondrial proton/calcium exchanger protein (LETM1) OT8N4MRU LETM1_HUMAN Decreases Expression [8]
Kinesin-like protein KIF20A (KIF20A) OTXOQHE0 KI20A_HUMAN Decreases Expression [8]
Chromosome-associated kinesin KIF4A (KIF4A) OT3UWL7D KIF4A_HUMAN Decreases Expression [8]
Phosphoacetylglucosamine mutase (PGM3) OTHS1ZSP AGM1_HUMAN Increases Expression [8]
Echinoderm microtubule-associated protein-like 2 (EML2) OTRX2NTA EMAL2_HUMAN Increases Expression [8]
Securin (PTTG1) OTIMYS4W PTTG1_HUMAN Decreases Expression [8]
Cytochrome b (CYTB) OTAHB98A CYB_HUMAN Decreases Expression [8]
Cytochrome b5 (CYB5A) OT6SN4RM CYB5_HUMAN Decreases Expression [8]
Cytochrome c oxidase subunit 1 (COX1) OTG3O9BN COX1_HUMAN Decreases Expression [8]
Cytochrome c oxidase subunit 2 (COX2) OTTMVBJJ COX2_HUMAN Decreases Expression [8]
Cytochrome c oxidase subunit 3 (COX3) OTNNGBYJ COX3_HUMAN Decreases Expression [8]
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) OTOEEEXG HPRT_HUMAN Decreases Expression [8]
Aspartate aminotransferase, mitochondrial (GOT2) OT6XBWN0 AATM_HUMAN Decreases Expression [8]
Phosphoglycerate kinase 1 (PGK1) OT6V1ICH PGK1_HUMAN Decreases Expression [8]
ATP synthase subunit a (ATP6) OTPHOGLX ATP6_HUMAN Decreases Expression [8]
Complement C5 (C5) OTSL3OIC CO5_HUMAN Increases Expression [8]
Low-density lipoprotein receptor (LDLR) OTH559LU LDLR_HUMAN Decreases Expression [8]
NADH-ubiquinone oxidoreductase chain 1 (ND1) OTCLGIXV NU1M_HUMAN Decreases Expression [8]
NADH-ubiquinone oxidoreductase chain 2 (ND2) OTG9OHOX NU2M_HUMAN Decreases Expression [8]
NADH-ubiquinone oxidoreductase chain 3 (ND3) OT1OC3K3 NU3M_HUMAN Decreases Expression [8]
NADH-ubiquinone oxidoreductase chain 4L (ND4L) OTTMZA4Q NU4LM_HUMAN Decreases Expression [8]
NADH-ubiquinone oxidoreductase chain 4 (ND4) OT4RQVAA NU4M_HUMAN Decreases Expression [8]
NADH-ubiquinone oxidoreductase chain 5 (ND5) OT45LW1K NU5M_HUMAN Decreases Expression [8]
NADH-ubiquinone oxidoreductase chain 6 (ND6) OTG47B7B NU6M_HUMAN Decreases Expression [8]
ATP synthase protein 8 (ATP8) OTYQQR53 ATP8_HUMAN Decreases Expression [8]
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) OTRT3F3U HMDH_HUMAN Decreases Expression [8]
RAF proto-oncogene serine/threonine-protein kinase (RAF1) OT51LSFO RAF1_HUMAN Decreases Expression [8]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Decreases Expression [8]
Ornithine aminotransferase, mitochondrial (OAT) OTEKO8CT OAT_HUMAN Decreases Expression [8]
Thymidine kinase, cytosolic (TK1) OTY5JFM1 KITH_HUMAN Decreases Expression [8]
N-myc proto-oncogene protein (MYCN) OTWD33K1 MYCN_HUMAN Decreases Expression [8]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) OTEG4KU9 RPN1_HUMAN Increases Expression [8]
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) OTXUN47K PCCB_HUMAN Decreases Expression [8]
ATP synthase F(0) complex subunit C1, mitochondrial (ATP5MC1) OTOLSYOI AT5G1_HUMAN Decreases Expression [8]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Decreases Expression [8]
Glia-derived nexin (SERPINE2) OTYF5340 GDN_HUMAN Increases Expression [8]
Acyl-CoA-binding protein (DBI) OT884QY9 ACBP_HUMAN Decreases Expression [8]
Vitamin K-dependent protein S (PROS1) OTXQWNOI PROS_HUMAN Decreases Expression [8]
Protein disulfide-isomerase (P4HB) OTTYNYPF PDIA1_HUMAN Increases Expression [8]
Bifunctional glutamate/proline--tRNA ligase (EPRS1) OTXK0FLB SYEP_HUMAN Increases Expression [8]
Heat shock protein HSP 90-alpha (HSP90AA1) OTLG1WPK HS90A_HUMAN Decreases Expression [8]
Laminin subunit beta-1 (LAMB1) OT6J9LJR LAMB1_HUMAN Increases Expression [8]
Proto-oncogene tyrosine-protein kinase receptor Ret (RET) OTLU040A RET_HUMAN Decreases Expression [8]
Fumarate hydratase, mitochondrial (FH) OTEQWU6Q FUMH_HUMAN Decreases Expression [8]
Amino acid transporter heavy chain SLC3A2 (SLC3A2) OTBR33M9 4F2_HUMAN Increases Expression [8]
Signal recognition particle receptor subunit alpha (SRPRA) OT5NMYTY SRPRA_HUMAN Increases Expression [8]
Asparagine synthetase (ASNS) OT8R922G ASNS_HUMAN Increases Expression [8]
Annexin A5 (ANXA5) OTZS877V ANXA5_HUMAN Increases Expression [8]
Neuromedin-B (NMB) OT4NLN6H NMB_HUMAN Decreases Expression [8]
Hemoglobin subunit theta-1 (HBQ1) OTU12ZTW HBAT_HUMAN Decreases Expression [8]
Galectin-1 (LGALS1) OT8LDFWR LEG1_HUMAN Decreases Expression [8]
Fructose-1,6-bisphosphatase 1 (FBP1) OTQBANEP F16P1_HUMAN Decreases Expression [8]
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) OT378CU9 DLDH_HUMAN Decreases Expression [8]
Cytochrome c oxidase subunit 6C (COX6C) OT3V7JE5 COX6C_HUMAN Decreases Expression [8]
Fructose-bisphosphate aldolase C (ALDOC) OTEC13I5 ALDOC_HUMAN Decreases Expression [8]
Thymosin beta-15A (TMSB15A) OTSBWCES TB15A_HUMAN Decreases Expression [8]
Heat shock 70 kDa protein 1A (HSPA1A) OTKGIE76 HS71A_HUMAN Decreases Expression [8]
Alpha-amylase 1B (AMY1A) OT6G4B8O AMY1B_HUMAN Decreases Expression [8]
Transcriptional activator Myb (MYB) OTJH64IV MYB_HUMAN Decreases Expression [8]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Increases Expression [8]
Chromogranin-A (CHGA) OTXYX5JH CMGA_HUMAN Decreases Expression [8]
Mast/stem cell growth factor receptor Kit (KIT) OTHUY3VZ KIT_HUMAN Increases Expression [8]
60 kDa heat shock protein, mitochondrial (HSPD1) OTTO1Y11 CH60_HUMAN Decreases Expression [8]
Heat shock cognate 71 kDa protein (HSPA8) OTJI2RCI HSP7C_HUMAN Decreases Expression [8]
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) OT2NHE5E ODPB_HUMAN Decreases Expression [8]
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) OTMKHVWC C1TC_HUMAN Decreases Expression [8]
Proliferating cell nuclear antigen (PCNA) OTHZ1RIA PCNA_HUMAN Decreases Expression [8]
Neurofilament heavy polypeptide (NEFH) OTMSCW5I NFH_HUMAN Decreases Expression [8]
ADP/ATP translocase 1 (SLC25A4) OTKYLK2J ADT1_HUMAN Decreases Expression [8]
Creatine kinase B-type (CKB) OTUCKOTT KCRB_HUMAN Decreases Expression [8]
Alpha-actinin-1 (ACTN1) OTUCLNXH ACTN1_HUMAN Decreases Expression [8]
Secretogranin-2 (SCG2) OTUHXX8U SCG2_HUMAN Increases Expression [8]
Protein disulfide-isomerase A4 (PDIA4) OTVFUJ13 PDIA4_HUMAN Increases Expression [8]
Plastin-3 (PLS3) OTYBM4PK PLST_HUMAN Increases Expression [8]
Beta-enolase (ENO3) OT3HYKYI ENOB_HUMAN Increases Expression [8]
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2) OT1LQSGX MTDC_HUMAN Increases Expression [8]
Pyruvate kinase PKM (PKM) OTLHHMC2 KPYM_HUMAN Decreases Expression [8]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Decreases Expression [8]
Cytochrome c oxidase subunit 6B1 (COX6B1) OTNKXYQI CX6B1_HUMAN Decreases Expression [8]
Platelet-derived growth factor receptor alpha (PDGFRA) OTDJXUCN PGFRA_HUMAN Decreases Expression [8]
Histone H1.2 (H1-2) OT0AVI4M H12_HUMAN Increases Expression [8]
Stathmin (STMN1) OTDJ4RV0 STMN1_HUMAN Decreases Expression [8]
Protein kinase C alpha type (PRKCA) OT5UWNRD KPCA_HUMAN Decreases Expression [8]
CCAAT/enhancer-binding protein beta (CEBPB) OTM9MQIA CEBPB_HUMAN Increases Expression [8]
Neuromodulin (GAP43) OT2OTGGV NEUM_HUMAN Decreases Expression [8]
CTP synthase 1 (CTPS1) OTZ9J6ZG PYRG1_HUMAN Decreases Expression [8]
Insulin-like growth factor-binding protein 3 (IGFBP3) OTIX63TX IBP3_HUMAN Increases Expression [8]
Insulin-like growth factor-binding protein 2 (IGFBP2) OTG1P60E IBP2_HUMAN Decreases Expression [8]
ADP-ribosylation factor 4 (ARF4) OT3GMDHA ARF4_HUMAN Increases Expression [8]
Early growth response protein 1 (EGR1) OTCP6XGZ EGR1_HUMAN Decreases Expression [8]
Phosphoglycerate mutase 1 (PGAM1) OTZ5DB06 PGAM1_HUMAN Decreases Expression [8]
NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2) OTSZF7D6 NDUV2_HUMAN Decreases Expression [8]
Casein kinase II subunit alpha' (CSNK2A2) OT7MA2LV CSK22_HUMAN Increases Expression [8]
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) OTXF0B09 IF2B_HUMAN Increases Expression [8]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Decreases Expression [8]
Aromatic-L-amino-acid decarboxylase (DDC) OT0TSW09 DDC_HUMAN Decreases Expression [8]
Amine oxidase A (MAOA) OT8NIWMQ AOFA_HUMAN Decreases Expression [8]
Diamine acetyltransferase 1 (SAT1) OT52AU22 SAT1_HUMAN Increases Expression [8]
Oxysterol-binding protein 1 (OSBP) OT7R0OQQ OSBP1_HUMAN Increases Expression [8]
Galanin peptides (GAL) OTB3VPTO GALA_HUMAN Decreases Expression [8]
NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR) OTPDCK1F ADRO_HUMAN Increases Expression [8]
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) OTBZKX4P ROA2_HUMAN Decreases Expression [8]
Splicing factor, proline- and glutamine-rich (SFPQ) OTLCIAPJ SFPQ_HUMAN Decreases Expression [8]
Peptidyl-prolyl cis-trans isomerase B (PPIB) OTLPH6KN PPIB_HUMAN Increases Expression [8]
Glycine dehydrogenase (GLDC) OTVVDNW0 GCSP_HUMAN Decreases Expression [8]
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) OTOCBX7P TNFL4_HUMAN Increases Expression [8]
Endothelial transcription factor GATA-2 (GATA2) OTBP2QQ2 GATA2_HUMAN Decreases Expression [8]
Ribonucleoside-diphosphate reductase large subunit (RRM1) OTXGQOR9 RIR1_HUMAN Decreases Expression [8]
Cytochrome c oxidase subunit 7B, mitochondrial (COX7B) OT67PIDP COX7B_HUMAN Decreases Expression [8]
Protein kinase C eta type (PRKCH) OTC498N5 KPCL_HUMAN Decreases Expression [8]
Tenascin (TNC) OTK4FSHR TENA_HUMAN Decreases Expression [8]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Decreases Expression [8]
DNA replication licensing factor MCM3 (MCM3) OTOOHQPM MCM3_HUMAN Decreases Expression [8]
Laminin subunit alpha-1 (LAMA1) OTQZMP86 LAMA1_HUMAN Decreases Expression [8]
ATP synthase subunit alpha, mitochondrial (ATP5F1A) OT3FZDLX ATPA_HUMAN Increases Expression [8]
Proteasome subunit alpha type-2 (PSMA2) OTJRT2ZL PSA2_HUMAN Decreases Expression [8]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Decreases Expression [8]
Threonine--tRNA ligase 1, cytoplasmic (TARS1) OT0PWST5 SYTC_HUMAN Increases Expression [8]
Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) OTHBZHX0 FKBP2_HUMAN Increases Expression [8]
Hepatocyte growth factor-like protein (MST1) OTOC4UNG HGFL_HUMAN Increases Expression [8]
Adenylate kinase 4, mitochondrial (AK4) OTA0T02Q KAD4_HUMAN Decreases Expression [8]
Calreticulin (CALR) OTYD2TR1 CALR_HUMAN Increases Expression [8]
Calnexin (CANX) OTYP1F6J CALX_HUMAN Increases Expression [8]
Cellular retinoic acid-binding protein 2 (CRABP2) OTY01V9G RABP2_HUMAN Decreases Expression [8]
Cellular retinoic acid-binding protein 1 (CRABP1) OTISDG5X RABP1_HUMAN Decreases Expression [8]
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) OTLB2WEU PRDX3_HUMAN Decreases Expression [8]
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) OTYA3GB4 2AAA_HUMAN Decreases Expression [8]
Neuronal acetylcholine receptor subunit alpha-5 (CHRNA5) OTGIL2YD ACHA5_HUMAN Decreases Expression [8]
Translocator protein (TSPO) OTSU7ESK TSPO_HUMAN Decreases Expression [8]
High affinity cationic amino acid transporter 1 (SLC7A1) OTR2ZVA8 CTR1_HUMAN Increases Expression [8]
Neuronal acetylcholine receptor subunit beta-4 (CHRNB4) OTIV4MC1 ACHB4_HUMAN Decreases Expression [8]
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) OTOJ8QFF SDHA_HUMAN Decreases Expression [8]
Coronin-1A (CORO1A) OTVAZOHC COR1A_HUMAN Decreases Expression [8]
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) OTOB6J6R RIR2_HUMAN Decreases Expression [8]
DnaJ homolog subfamily A member 1 (DNAJA1) OT38BZQQ DNJA1_HUMAN Decreases Expression [8]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Decreases Phosphorylation [8]
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) OTCMMMIZ 3HIDH_HUMAN Decreases Expression [8]
Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3) OTCZQY1U ACHA3_HUMAN Decreases Expression [8]
Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) OTQHB52T P5CR1_HUMAN Increases Expression [8]
Cleavage stimulation factor subunit 2 (CSTF2) OTR6G4II CSTF2_HUMAN Decreases Expression [8]
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) OT0THBVA DUT_HUMAN Decreases Expression [8]
ER lumen protein-retaining receptor 2 (KDELR2) OT9QW7Q0 ERD22_HUMAN Increases Expression [8]
DNA replication licensing factor MCM4 (MCM4) OT19PNNG MCM4_HUMAN Decreases Expression [8]
DNA replication licensing factor MCM5 (MCM5) OTAHLB62 MCM5_HUMAN Decreases Expression [8]
Serine hydroxymethyltransferase, mitochondrial (SHMT2) OT5NCAZN GLYM_HUMAN Increases Expression [8]
Heat shock 70 kDa protein 1-like (HSPA1L) OTC2V1K6 HS71L_HUMAN Decreases Expression [8]
Prohibitin 1 (PHB1) OTZNXYS2 PHB1_HUMAN Decreases Expression [8]
Myosin-10 (MYH10) OTXN2WXS MYH10_HUMAN Decreases Expression [8]
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) OTRO9RII HMGCL_HUMAN Increases Expression [8]
Lon protease homolog, mitochondrial (LONP1) OT665WYT LONM_HUMAN Increases Expression [8]
Pigment epithelium-derived factor (SERPINF1) OTWZH98J PEDF_HUMAN Increases Expression [8]
Squalene synthase (FDFT1) OTGDISIT FDFT_HUMAN Decreases Expression [8]
Transgelin-2 (TAGLN2) OTUXZGDQ TAGL2_HUMAN Decreases Expression [8]
Stress-70 protein, mitochondrial (HSPA9) OT4TMVS9 GRP75_HUMAN Increases Expression [8]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST) OT39PDMS OST48_HUMAN Increases Expression [8]
ADP-ribosylation factor-like protein 1 (ARL1) OTB6N6BR ARL1_HUMAN Increases Expression [8]
Replication factor C subunit 3 (RFC3) OT1MS7AO RFC3_HUMAN Decreases Expression [8]
Cyclin-F (CCNF) OTJFVU43 CCNF_HUMAN Decreases Expression [8]
ETS translocation variant 5 (ETV5) OTE2OBM4 ETV5_HUMAN Decreases Expression [8]
Peripherin (PRPH) OT6VUH78 PERI_HUMAN Increases Expression [8]
Glycine--tRNA ligase (GARS1) OT5B6R9Y GARS_HUMAN Increases Expression [8]
Eukaryotic translation initiation factor 1 (EIF1) OTB4GZ0V EIF1_HUMAN Increases Expression [8]
Neutral amino acid transporter A (SLC1A4) OTVODHAE SATT_HUMAN Increases Expression [8]
Carnitine O-acetyltransferase (CRAT) OTSCLZ04 CACP_HUMAN Increases Expression [8]
ETS translocation variant 4 (ETV4) OT8C98UZ ETV4_HUMAN Decreases Expression [8]
Ran-specific GTPase-activating protein (RANBP1) OTQE226K RANG_HUMAN Decreases Expression [8]
Peptidyl-prolyl cis-trans isomerase C (PPIC) OTY5Q42N PPIC_HUMAN Increases Expression [8]
Proliferation marker protein Ki-67 (MKI67) OTA8N1QI KI67_HUMAN Decreases Expression [8]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) OTDPS6AV STT3A_HUMAN Increases Expression [8]
Retinaldehyde dehydrogenase 3 (ALDH1A3) OT1C9NKQ AL1A3_HUMAN Decreases Expression [8]
Sodium- and chloride-dependent glycine transporter 1 (SLC6A9) OTHRUON2 SC6A9_HUMAN Increases Expression [8]
Prolyl endopeptidase (PREP) OTSJZBB5 PPCE_HUMAN Decreases Expression [8]
ATP synthase F(0) complex subunit C3, mitochondrial (ATP5MC3) OTX674BU AT5G3_HUMAN Decreases Expression [8]
DNA-binding protein RFX5 (RFX5) OT73KJ5P RFX5_HUMAN Decreases Expression [8]
Coatomer subunit delta (ARCN1) OTJ96STE COPD_HUMAN Increases Expression [8]
Nestin (NES) OTZ9PZ14 NEST_HUMAN Decreases Expression [8]
Aminomethyltransferase, mitochondrial (AMT) OTQYEWZQ GCST_HUMAN Increases Expression [8]
Histone H3-like centromeric protein A (CENPA) OT0NEJ4X CENPA_HUMAN Decreases Expression [8]
Serine--tRNA ligase, cytoplasmic (SARS1) OTFKXQ1O SYSC_HUMAN Increases Expression [8]
DNA replication licensing factor MCM2 (MCM2) OTGGORIQ MCM2_HUMAN Decreases Expression [8]
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) OT50L4XB ACADV_HUMAN Increases Expression [8]
Transmembrane emp24 domain-containing protein 10 (TMED10) OTUXSHH7 TMEDA_HUMAN Increases Expression [8]
Inactive serine/threonine-protein kinase 19 (STK19) OTYM6437 STK19_HUMAN Increases Expression [8]
Isocitrate dehydrogenase subunit alpha, mitochondrial (IDH3A) OT5QQB5L IDH3A_HUMAN Increases Expression [8]
Serpin H1 (SERPINH1) OTKGI7BS SERPH_HUMAN Increases Expression [8]
Achaete-scute homolog 1 (ASCL1) OTI4X44G ASCL1_HUMAN Increases Expression [8]
Biotin--protein ligase (HLCS) OTPDUX30 BPL1_HUMAN Increases Expression [8]
Death-associated protein 1 (DAP) OT5YLL7E DAP1_HUMAN Increases Expression [8]
Translocon-associated protein subunit delta (SSR4) OTBWBGMR SSRD_HUMAN Increases Expression [8]
Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1) OTF3TBTK SSDH_HUMAN Decreases Expression [8]
Lumican (LUM) OTSRC874 LUM_HUMAN Decreases Expression [8]
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) OT4O4NFS ROA3_HUMAN Decreases Expression [8]
Kinesin-like protein KIF11 (KIF11) OTHRGLCQ KIF11_HUMAN Decreases Expression [8]
Hexokinase-2 (HK2) OTC0GCQO HXK2_HUMAN Decreases Expression [8]
Large ribosomal subunit protein bL12m (MRPL12) OTU41AM0 RM12_HUMAN Decreases Expression [8]
Thimet oligopeptidase (THOP1) OT9E148D THOP1_HUMAN Decreases Expression [8]
Tricarboxylate transport protein, mitochondrial (SLC25A1) OTIDXQ9F TXTP_HUMAN Decreases Expression [8]
CCAAT/enhancer-binding protein gamma (CEBPG) OTGNAX3H CEBPG_HUMAN Increases Expression [8]
Coatomer subunit alpha (COPA) OTZ1DTXU COPA_HUMAN Increases Expression [8]
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1) OTYHXLWZ BCAT1_HUMAN Increases Expression [8]
Adenylate kinase 2, mitochondrial (AK2) OTZG3X2H KAD2_HUMAN Decreases Expression [8]
Microfibril-associated glycoprotein 4 (MFAP4) OT5W64QY MFAP4_HUMAN Increases Expression [8]
Mesencephalic astrocyte-derived neurotrophic factor (MANF) OT2AH8VJ MANF_HUMAN Increases Expression [8]
Cadherin-15 (CDH15) OTJ1TO02 CAD15_HUMAN Increases Expression [8]
Protein SEC13 homolog (SEC13) OTSR4WWM SEC13_HUMAN Increases Expression [8]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Decreases Expression [8]
ATP synthase subunit f, mitochondrial (ATP5MF) OTE4TBG9 ATPK_HUMAN Decreases Expression [8]
Homeobox protein DLX-5 (DLX5) OTEEFBEU DLX5_HUMAN Decreases Expression [8]
Methionine--tRNA ligase, cytoplasmic (MARS1) OTLJ6MHJ SYMC_HUMAN Increases Expression [8]
DNA polymerase epsilon subunit 2 (POLE2) OTAC9V6L DPOE2_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 alpha subcomplex subunit 6 (NDUFA6) OTEOIIOL NDUA6_HUMAN Decreases Expression [8]
Sestrin-2 (SESN2) OT889IXY SESN2_HUMAN Increases Expression [8]
Anthrax toxin receptor 2 (ANTXR2) OTOGFGOJ ANTR2_HUMAN Increases Expression [8]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (GNG2) OT05Z3MC GBG2_HUMAN Decreases Expression [8]
Triosephosphate isomerase (TPI1) OT14KP4B TPIS_HUMAN Decreases Expression [8]
Protein transport protein Sec61 subunit beta (SEC61B) OTY1X6A2 SC61B_HUMAN Increases Expression [8]
Ribose-phosphate pyrophosphokinase 1 (PRPS1) OTN3A6CN PRPS1_HUMAN Decreases Expression [8]
Neurocalcin-delta (NCALD) OTJZ8UEL NCALD_HUMAN Decreases Expression [8]
10 kDa heat shock protein, mitochondrial (HSPE1) OT7JSZLB CH10_HUMAN Decreases Expression [8]
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) OTLBE3CB S61A1_HUMAN Increases Expression [8]
Large ribosomal subunit protein eL37 (RPL37) OTB6SDZ1 RL37_HUMAN Increases Expression [8]
LIM domain transcription factor LMO4 (LMO4) OT5NDCT9 LMO4_HUMAN Increases Expression [8]
Estrogen-related receptor gamma (ESRRG) OTC3A0KU ERR3_HUMAN Decreases Expression [8]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Increases Expression [8]
Histone H2B type 1-C/E/F/G/I (H2BC10) OTLQH0D6 H2B1C_HUMAN Increases Expression [8]
Inward rectifier potassium channel 2 (KCNJ2) OT2OQEZS KCNJ2_HUMAN Increases Expression [8]
Actin, cytoplasmic 2 (ACTG1) OTH4V7VQ ACTG_HUMAN Decreases Expression [8]
Thymosin beta-10 (TMSB10) OTLVZ13T TYB10_HUMAN Decreases Expression [8]
Disks large homolog 4 (DLG4) OTD9E2LU DLG4_HUMAN Increases Expression [8]
UDP-galactose translocator (SLC35A2) OTQOTOWZ S35A2_HUMAN Increases Expression [8]
Solute carrier family 35 member B1 (SLC35B1) OTJ1MRN2 S35B1_HUMAN Increases Expression [8]
Arginase-2, mitochondrial (ARG2) OTCPI0E8 ARGI2_HUMAN Decreases Expression [8]
ETS-related transcription factor Elf-3 (ELF3) OTUTLEQO ELF3_HUMAN Decreases Expression [8]
Nucleobindin-2 (NUCB2) OTHO6JWN NUCB2_HUMAN Increases Expression [8]
Protein delta homolog 1 (DLK1) OTE1VLNB DLK1_HUMAN Decreases Expression [8]
Brain acid soluble protein 1 (BASP1) OTF4VS5G BASP1_HUMAN Decreases Expression [8]
G-protein-signaling modulator 2 (GPSM2) OT6RPMRM GPSM2_HUMAN Decreases Expression [8]
TATA element modulatory factor (TMF1) OT7JY7UF TMF1_HUMAN Increases Expression [8]
Small ribosomal subunit protein mS25 (MRPS25) OTN7IISS RT25_HUMAN Decreases Expression [8]
Small ribosomal subunit protein bS6m (MRPS6) OTKFY73U RT06_HUMAN Decreases Expression [8]
Serine/arginine-rich splicing factor 3 (SRSF3) OTOFT707 SRSF3_HUMAN Decreases Expression [8]
Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) OT1SLUZH TSG6_HUMAN Decreases Expression [8]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Decreases Expression [8]
Transcription factor A, mitochondrial (TFAM) OTXXV5V7 TFAM_HUMAN Decreases Expression [8]
Solute carrier family 25 member 3 (SLC25A3) OTAWGR4K S25A3_HUMAN Increases Expression [8]
Transcription factor E2F1 (E2F1) OTLKYBBC E2F1_HUMAN Decreases Expression [8]
Serine/arginine-rich splicing factor 2 (SRSF2) OTVDHO6U SRSF2_HUMAN Decreases Expression [8]
N-acetylgalactosamine kinase (GALK2) OTHR35JF GALK2_HUMAN Increases Expression [8]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) OTCO26FV HMCS1_HUMAN Decreases Expression [8]
Large neutral amino acids transporter small subunit 1 (SLC7A5) OT2WPVXD LAT1_HUMAN Increases Expression [8]
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) OTFP7AA8 PFKAP_HUMAN Decreases Expression [8]
Cerebellar degeneration-related protein 2 (CDR2) OTD3ZJST CDR2_HUMAN Increases Expression [8]
A-kinase anchor protein 17A (AKAP17A) OT2CEJW4 AK17A_HUMAN Increases Expression [8]
Myosin light chain 5 (MYL5) OT7CQ24K MYL5_HUMAN Increases Expression [8]
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase , mitochondrial (ALDH6A1) OT8LCZCT MMSA_HUMAN Increases Expression [8]
DNA-binding protein inhibitor ID-2 (ID2) OT0U1D53 ID2_HUMAN Increases Expression [8]
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) OT7EVFBK M2OM_HUMAN Decreases Expression [8]
Histone-lysine N-methyltransferase MECOM (MECOM) OTP983W8 MECOM_HUMAN Decreases Expression [8]
Lamin-B2 (LMNB2) OTXRDUOS LMNB2_HUMAN Decreases Expression [8]
Glutamine--fructose-6-phosphate aminotransferase 1 (GFPT1) OTQBDO45 GFPT1_HUMAN Increases Expression [8]
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) OTPYQX3K C1QBP_HUMAN Decreases Expression [8]
Quinone oxidoreductase (CRYZ) OTD2F4C8 QOR_HUMAN Decreases Expression [8]
Golgin subfamily A member 3 (GOLGA3) OT27354E GOGA3_HUMAN Increases Expression [8]
Golgin subfamily A member 2 (GOLGA2) OT5S9KYM GOGA2_HUMAN Increases Expression [8]
Testican-1 (SPOCK1) OTLTDGK7 TICN1_HUMAN Decreases Expression [8]
Protoheme IX farnesyltransferase, mitochondrial (COX10) OTCYIS0L COX10_HUMAN Increases Expression [8]
Tyrosine-protein phosphatase non-receptor type 13 (PTPN13) OTESFZSO PTN13_HUMAN Increases Expression [8]
Heat shock protein 75 kDa, mitochondrial (TRAP1) OTNG0L8J TRAP1_HUMAN Decreases Expression [8]
TNF receptor-associated factor 2 (TRAF2) OT1MEZZN TRAF2_HUMAN Decreases Expression [8]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Decreases Expression [8]
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) OTA0UNHM ECH1_HUMAN Increases Expression [8]
Chromatin assembly factor 1 subunit A (CHAF1A) OTXSSY4H CAF1A_HUMAN Decreases Expression [8]
Chromatin assembly factor 1 subunit B (CHAF1B) OTOMK4KH CAF1B_HUMAN Decreases Expression [8]
Syntaxin-5 (STX5) OTQ0024B STX5_HUMAN Increases Expression [8]
G protein pathway suppressor 2 (GPS2) OT065FSS GPS2_HUMAN Increases Expression [8]
Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1) OTXNGZCG MD2L1_HUMAN Decreases Expression [8]
Ras GTPase-activating protein-binding protein 1 (G3BP1) OT7CJLY8 G3BP1_HUMAN Decreases Expression [8]
Protein OS-9 (OS9) OTB5B2TY OS9_HUMAN Increases Expression [8]
Limbic system-associated membrane protein (LSAMP) OTYXVQX2 LSAMP_HUMAN Increases Expression [8]
Ras-related protein Rab-32 (RAB32) OTTR4H7S RAB32_HUMAN Increases Expression [8]
Mannosyl-oligosaccharide glucosidase (MOGS) OT99MBGB MOGS_HUMAN Increases Expression [8]
CD166 antigen (ALCAM) OTCO4LP7 CD166_HUMAN Increases Expression [8]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2) OTTUU92F ENPP2_HUMAN Decreases Expression [8]
Methylglutaconyl-CoA hydratase, mitochondrial (AUH) OT8VKBXX AUHM_HUMAN Increases Expression [8]
Cytochrome c oxidase copper chaperone (COX17) OTCP4LH2 COX17_HUMAN Decreases Expression [8]
Low-density lipoprotein receptor-related protein 8 (LRP8) OTZ71YV2 LRP8_HUMAN Decreases Expression [8]
Malectin (MLEC) OTOPGRF5 MLEC_HUMAN Increases Expression [8]
DNA polymerase alpha subunit B (POLA2) OTTWQ73N DPOA2_HUMAN Decreases Expression [8]
Dihydropyrimidinase-related protein 3 (DPYSL3) OTINJV20 DPYL3_HUMAN Decreases Expression [8]
Transcription factor E2F2 (E2F2) OTO75RM7 E2F2_HUMAN Decreases Expression [8]
Endonuclease G, mitochondrial (ENDOG) OT5IM7B3 NUCG_HUMAN Decreases Expression [8]
Squalene monooxygenase (SQLE) OT0GGRDO ERG1_HUMAN Decreases Expression [8]
Protein disulfide-isomerase A5 (PDIA5) OT76ZSX5 PDIA5_HUMAN Increases Expression [8]
DNA replication licensing factor MCM6 (MCM6) OTKLIAWT MCM6_HUMAN Decreases Expression [8]
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) OTGQ2AOJ ITPR3_HUMAN Decreases Expression [8]
Maternal embryonic leucine zipper kinase (MELK) OTEY2UQA MELK_HUMAN Decreases Expression [8]
Neutral alpha-glucosidase AB (GANAB) OTYLXY4M GANAB_HUMAN Increases Expression [8]
Raftlin (RFTN1) OT8875JE RFTN1_HUMAN Decreases Expression [8]
Major vault protein (MVP) OTJGHJRB MVP_HUMAN Increases Expression [8]
PCNA-associated factor (PCLAF) OTMVIOUU PAF15_HUMAN Decreases Expression [8]
Signal peptidase complex subunit 2 (SPCS2) OTCGTTLY SPCS2_HUMAN Increases Expression [8]
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1) OT9EROL6 HERP1_HUMAN Increases Expression [8]
Leucine--tRNA ligase, mitochondrial (LARS2) OTJS37LE SYLM_HUMAN Decreases Expression [8]
Mitochondrial inner membrane protein OXA1L (OXA1L) OTS0BFRD OXA1L_HUMAN Increases Expression [8]
Protein disulfide-isomerase A6 (PDIA6) OT8YBR17 PDIA6_HUMAN Increases Expression [8]
kinase isozyme 2, mitochondrial (PDK2) OTM436F9 PDK2_HUMAN Increases Expression [8]
kinase isozyme 3, mitochondrial (PDK3) OTCPSTID PDK3_HUMAN Decreases Expression [8]
Serum paraoxonase/arylesterase 2 (PON2) OT55NCTD PON2_HUMAN Decreases Expression [8]
Reticulocalbin-1 (RCN1) OT3JBGAG RCN1_HUMAN Increases Expression [8]
Transmembrane emp24 domain-containing protein 2 (TMED2) OTBLO7RW TMED2_HUMAN Increases Expression [8]
Mitochondrial fission regulator 1 (MTFR1) OTLB1VFT MTFR1_HUMAN Increases Expression [8]
Delta(24)-sterol reductase (DHCR24) OTP301JW DHC24_HUMAN Decreases Expression [8]
Disks large-associated protein 5 (DLGAP5) OTWCN39U DLGP5_HUMAN Decreases Expression [8]
Calponin-3 (CNN3) OTJTAXAP CNN3_HUMAN Decreases Expression [8]
Protein transport protein Sec23A (SEC23A) OTBRNIJ3 SC23A_HUMAN Increases Expression [8]
SH2 domain-containing adapter protein B (SHB) OTF2HSC0 SHB_HUMAN Decreases Expression [8]
Surfeit locus protein 1 (SURF1) OTAINRSS SURF1_HUMAN Increases Expression [8]
Transcriptional enhancer factor TEF-4 (TEAD2) OTM8YMYT TEAD2_HUMAN Decreases Expression [8]
Translocating chain-associated membrane protein 1 (TRAM1) OT3I0H8E TRAM1_HUMAN Increases Expression [8]
Mitochondrial import receptor subunit TOM34 (TOMM34) OTH6MITE TOM34_HUMAN Decreases Expression [8]
Methylsterol monooxygenase 1 (MSMO1) OTKV62RZ MSMO1_HUMAN Decreases Expression [8]
Proline-rich protein 4 (PRR4) OT26I382 PROL4_HUMAN Increases Expression [8]
Neuronatin (NNAT) OTNRLO7G NNAT_HUMAN Decreases Expression [8]
Cryptochrome-1 (CRY1) OTTGAJT0 CRY1_HUMAN Decreases Expression [8]
Cysteine and glycine-rich protein 2 (CSRP2) OT4SW0HI CSRP2_HUMAN Decreases Expression [8]
Large ribosomal subunit protein uL23m (MRPL23) OT7H7PM2 RM23_HUMAN Decreases Expression [8]
Atypical chemokine receptor 1 (ACKR1) OT9M11LX ACKR1_HUMAN Increases Expression [8]
Neuronal regeneration-related protein (NREP) OT2AZPKK NREP_HUMAN Decreases Expression [8]
Serine/arginine-rich splicing factor 7 (SRSF7) OTRS4W4S SRSF7_HUMAN Decreases Expression [8]
Nuclear respiratory factor 1 (NRF1) OTOXWNV8 NRF1_HUMAN Decreases Expression [8]
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) OTEPHG0S CLPP_HUMAN Increases Expression [8]
Thiosulfate sulfurtransferase (TST) OTZ4F5LK THTR_HUMAN Increases Expression [8]
NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial (NDUFA9) OTMKQJJ8 NDUA9_HUMAN Decreases Expression [8]
Phosphoenolpyruvate carboxykinase , mitochondrial (PCK2) OTJ8LX4N PCKGM_HUMAN Decreases Expression [8]
Dual specificity protein phosphatase 6 (DUSP6) OT4H6RKW DUS6_HUMAN Decreases Expression [8]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Decreases Expression [8]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) OTQYEXL2 F264_HUMAN Decreases Expression [8]
DNA excision repair protein ERCC-6-like (ERCC6L) OTE9V7D9 ERC6L_HUMAN Decreases Expression [8]
Prolyl 3-hydroxylase 1 (P3H1) OT2TFW25 P3H1_HUMAN Increases Expression [8]
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (PAN2) OTB65N2I PAN2_HUMAN Increases Expression [8]
Fibronectin type III domain-containing protein 3B (FNDC3B) OTBILGDR FND3B_HUMAN Increases Expression [8]
BolA-like protein 3 (BOLA3) OTDEDY0S BOLA3_HUMAN Decreases Expression [8]
Protein Largen (PRR16) OTG4TEGR LARGN_HUMAN Decreases Expression [8]
Sigma intracellular receptor 2 (TMEM97) OTH76ZWK SGMR2_HUMAN Decreases Expression [8]
BEN domain-containing protein 6 (BEND6) OTF6H1TJ BEND6_HUMAN Increases Expression [8]
All trans-polyprenyl-diphosphate synthase PDSS1 (PDSS1) OTXGVHAB DPS1_HUMAN Decreases Expression [8]
KN motif and ankyrin repeat domain-containing protein 4 (KANK4) OT5WC0Q8 KANK4_HUMAN Increases Expression [8]
Lysophospholipase-like protein 1 (LYPLAL1) OT8F2DCV LYPL1_HUMAN Increases Expression [8]
KN motif and ankyrin repeat domain-containing protein 2 (KANK2) OT3SZIWM KANK2_HUMAN Decreases Expression [8]
Tensin-3 (TNS3) OTPG2D8Z TENS3_HUMAN Decreases Expression [8]
Rhomboid domain-containing protein 2 (RHBDD2) OTX54ILM RHBD2_HUMAN Increases Expression [8]
Magnesium transporter NIPA3 (NIPAL1) OTRYI60X NIPA3_HUMAN Decreases Expression [8]
Fidgetin-like protein 1 (FIGNL1) OTKII63K FIGL1_HUMAN Decreases Expression [8]
ATPase family AAA domain-containing protein 2 (ATAD2) OT8MCRNY ATAD2_HUMAN Decreases Expression [8]
Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC1S2) OTUR3E76 BL1S2_HUMAN Increases Expression [8]
Coiled-coil domain-containing protein 171 (CCDC171) OT9NL2D9 CC171_HUMAN Decreases Expression [8]
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) OTV01EFP C1TM_HUMAN Increases Expression [8]
Protein disulfide isomerase CRELD2 (CRELD2) OTL73AO8 CREL2_HUMAN Increases Expression [8]
Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) OTUJZIDC ISLR2_HUMAN Decreases Expression [8]
Zinc finger protein basonuclin-2 (BNC2) OTU22H9Z BNC2_HUMAN Decreases Expression [8]
LHFPL tetraspan subfamily member 2 protein (LHFPL2) OTDWEEBQ LHPL2_HUMAN Decreases Expression [8]
Patatin-like phospholipase domain-containing protein 7 (PNPLA7) OT5VSJX2 PLPL7_HUMAN Increases Expression [8]
Cytochrome P450 4V2 (CYP4V2) OTQKNK0D CP4V2_HUMAN Increases Expression [8]
Acyl-CoA dehydrogenase family member 11 (ACAD11) OT3T9HAX ACD11_HUMAN Increases Expression [8]
Cyclic AMP-responsive element-binding protein 3-like protein 2 (CREB3L2) OT09MHV0 CR3L2_HUMAN Increases Expression [8]
Centromere protein U (CENPU) OTQ4TZRS CENPU_HUMAN Decreases Expression [8]
Ribosomal protein eS27-like (RPS27L) OTZWHU0N RS27L_HUMAN Increases Expression [8]
Staphylococcal nuclease domain-containing protein 1 (SND1) OTT734JN SND1_HUMAN Increases Expression [8]
Protein MCM10 homolog (MCM10) OTV0O3JN MCM10_HUMAN Decreases Expression [8]
Histone H2A type 3 (H2AC25) OTPO62JI H2A3_HUMAN Increases Expression [8]
Endonuclease/exonuclease/phosphatase family domain-containing protein 1 (EEPD1) OTTOGO05 EEPD1_HUMAN Decreases Expression [8]
Carbohydrate sulfotransferase 15 (CHST15) OTNTM2SP CHSTF_HUMAN Increases Expression [8]
Proton-coupled amino acid transporter 1 (SLC36A1) OTIEL5QZ S36A1_HUMAN Decreases Expression [8]
Treslin (TICRR) OT2HKWOC TICRR_HUMAN Decreases Expression [8]
D-glutamate cyclase, mitochondrial (DGLUCY) OTZD17IM GLUCM_HUMAN Decreases Expression [8]
Protein MON2 homolog (MON2) OTCSVMAR MON2_HUMAN Increases Expression [8]
Protein ADM2 (ADM2) OTJVN41C ADM2_HUMAN Increases Expression [8]
Microtubule organization protein AKNA (AKNA) OTQ6E2C8 AKNA_HUMAN Increases Expression [8]
Pleckstrin homology domain-containing family H member 3 (PLEKHH3) OTREOQBO PKHH3_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase synoviolin (SYVN1) OTZ4ZJP5 SYVN1_HUMAN Increases Expression [8]
Suppressor APC domain-containing protein 2 (SAPCD2) OTXS0EXM SAPC2_HUMAN Decreases Expression [8]
Four-jointed box protein 1 (FJX1) OT8SVTSS FJX1_HUMAN Decreases Expression [8]
Poly(ADP-ribose) glycohydrolase (PARG) OT10JTIO PARG_HUMAN Decreases Expression [8]
RNA-binding protein MEX3D (MEX3D) OTAUWRK7 MEX3D_HUMAN Decreases Expression [8]
TIR domain-containing adapter molecule 2 (TICAM2) OTK7GIJ5 TCAM2_HUMAN Increases Expression [8]
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) OTZXD1UK NDUAB_HUMAN Decreases Expression [8]
ERO1-like protein beta (ERO1B) OTHZ25Y8 ERO1B_HUMAN Increases Expression [8]
Cerebellin-2 (CBLN2) OT29SSBE CBLN2_HUMAN Decreases Expression [8]
Protein HID1 (HID1) OTVJIFSU HID1_HUMAN Increases Expression [8]
Iron-sulfur cluster co-chaperone protein HscB (HSCB) OTP8YV25 HSC20_HUMAN Increases Expression [8]
Hydroxyacid-oxoacid transhydrogenase, mitochondrial (ADHFE1) OT8J2PD8 HOT_HUMAN Increases Expression [8]
DNA damage-induced apoptosis suppressor protein (DDIAS) OTTGG2PM DDIAS_HUMAN Decreases Expression [8]
Intraflagellar transport protein 20 homolog (IFT20) OTKJS2BZ IFT20_HUMAN Increases Expression [8]
Structure-specific endonuclease subunit SLX4 (SLX4) OTF6236I SLX4_HUMAN Decreases Expression [8]
Stabilizer of axonemal microtubules 1 (SAXO1) OT7M6PLA SAXO1_HUMAN Increases Expression [8]
Chondroitin sulfate synthase 2 (CHPF) OTLMP2VY CHSS2_HUMAN Increases Expression [8]
Transcription initiation factor TFIID subunit 1-like (TAF1L) OT9Z7EVA TAF1L_HUMAN Increases Expression [8]
Putative ribosome-binding factor A, mitochondrial (RBFA) OT69B0D9 RBFA_HUMAN Decreases Expression [8]
Probable phosphoglycerate mutase 4 (PGAM4) OT7WZRD0 PGAM4_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 alpha subcomplex assembly factor 2 (NDUFAF2) OTC8QPRS NDUF2_HUMAN Increases Expression [8]
Homeobox protein SIX5 (SIX5) OTT1I9WY SIX5_HUMAN Increases Expression [8]
Zinc transporter ZIP11 (SLC39A11) OT71LCT2 S39AB_HUMAN Increases Expression [8]
Protein FAM24B (FAM24B) OTN9XBAM FA24B_HUMAN Increases Expression [8]
Keratinocyte-associated protein 2 (KRTCAP2) OTRV6ORJ KTAP2_HUMAN Increases Expression [8]
Sodium-dependent lysophosphatidylcholine symporter 1 (MFSD2A) OTVG1VG0 NLS1_HUMAN Decreases Expression [8]
Neuropilin and tolloid-like protein 2 (NETO2) OT0YAMC0 NETO2_HUMAN Decreases Expression [8]
Transmembrane protein 116 (TMEM116) OTYDSA49 TM116_HUMAN Increases Expression [8]
Liprin-beta-2 (PPFIBP2) OTXQO55Y LIPB2_HUMAN Decreases Expression [8]
Probable aminopeptidase NPEPL1 (NPEPL1) OTMJF2RB PEPL1_HUMAN Increases Expression [8]
Phospholipid phosphatase 5 (PLPP5) OTHT51D6 PLPP5_HUMAN Increases Expression [8]
Atypical kinase COQ8A, mitochondrial (COQ8A) OT1ETSA2 COQ8A_HUMAN Increases Expression [8]
GrpE protein homolog 2, mitochondrial (GRPEL2) OTNF289O GRPE2_HUMAN Increases Expression [8]
Gasdermin-B (GSDMB) OTWA7P10 GSDMB_HUMAN Increases Expression [8]
DEP domain-containing mTOR-interacting protein (DEPTOR) OTCBP1BT DPTOR_HUMAN Increases Expression [8]
Golgin subfamily A member 5 (GOLGA5) OTG6HB6U GOGA5_HUMAN Increases Expression [8]
Guanine nucleotide exchange factor for Rab-3A (RAB3IL1) OT18H5HD R3GEF_HUMAN Increases Expression [8]
Mitochondria-eating protein (SPATA18) OTOEHTHU MIEAP_HUMAN Increases Expression [8]
Palmitoyl thioesterase CPT1C (CPT1C) OT8F1MBF CPT1C_HUMAN Increases Expression [8]
Minor histocompatibility antigen H13 (HM13) OTGEO1LP HM13_HUMAN Increases Expression [8]
Alanine aminotransferase 2 (GPT2) OTS5VF7N ALAT2_HUMAN Increases Expression [8]
Hepatitis A virus cellular receptor 2 (HAVCR2) OTOL603T HAVR2_HUMAN Increases Expression [8]
Volume-regulated anion channel subunit LRRC8C (LRRC8C) OT2Y51BP LRC8C_HUMAN Decreases Expression [8]
Protein Shroom3 (SHROOM3) OTQKC5X2 SHRM3_HUMAN Decreases Expression [8]
Conserved oligomeric Golgi complex subunit 1 (COG1) OT3JSAF7 COG1_HUMAN Increases Expression [8]
Cholinephosphotransferase 1 (CHPT1) OT4FJ0K3 CHPT1_HUMAN Increases Expression [8]
DEP domain-containing protein 1B (DEPDC1B) OTMVFOT1 DEP1B_HUMAN Decreases Expression [8]
Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) OT9HT0O1 NUDT8_HUMAN Decreases Expression [8]
RNA polymerase-associated protein LEO1 (LEO1) OTAPF4PA LEO1_HUMAN Decreases Expression [8]
Cytoglobin (CYGB) OTX153DQ CYGB_HUMAN Decreases Expression [8]
Protein phosphatase 1E (PPM1E) OTXRH3YA PPM1E_HUMAN Decreases Expression [8]
Transmembrane protein 158 (TMEM158) OT0KUBBI TM158_HUMAN Decreases Expression [8]
Transcription factor AP-2-beta (TFAP2B) OTR1T8E9 AP2B_HUMAN Decreases Expression [8]
ER degradation-enhancing alpha-mannosidase-like protein 1 (EDEM1) OTWHN69S EDEM1_HUMAN Increases Expression [8]
Nuclear pore complex protein Nup205 (NUP205) OTJKHCY6 NU205_HUMAN Decreases Expression [8]
GPI-anchor transamidase (PIGK) OTAFSYLD GPI8_HUMAN Increases Expression [8]
DNA repair and recombination protein RAD54-like (RAD54L) OTEGMAKG RAD54_HUMAN Decreases Expression [8]
Zinc finger protein neuro-d4 (DPF1) OTI4ZFP8 DPF1_HUMAN Decreases Expression [8]
NEDD4-binding protein 2-like 2 (N4BP2L2) OTV2F04G N42L2_HUMAN Increases Expression [8]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Increases Expression [8]
Glutaryl-CoA dehydrogenase, mitochondrial (GCDH) OTVQMZZN GCDH_HUMAN Decreases Expression [8]
Rho guanine nucleotide exchange factor 2 (ARHGEF2) OTBQTFRT ARHG2_HUMAN Increases Expression [8]
Interferon regulatory factor 7 (IRF7) OTC1A2PQ IRF7_HUMAN Increases Expression [8]
Histone H2A type 1-C (H2AC6) OTF3YK7V H2A1C_HUMAN Increases Expression [8]
Myeloid-derived growth factor (MYDGF) OT9HRPL6 MYDGF_HUMAN Increases Expression [8]
F-box only protein 32 (FBXO32) OTUE978R FBX32_HUMAN Increases Expression [8]
DNA topoisomerase I, mitochondrial (TOP1MT) OT2H77ID TOP1M_HUMAN Increases Expression [8]
Ras-related protein Rab-24 (RAB24) OTOFNAJK RAB24_HUMAN Increases Expression [8]
Mitochondrial amidoxime reducing component 2 (MTARC2) OT8B6LVD MARC2_HUMAN Increases Expression [8]
Transcription factor E2F7 (E2F7) OTWW358N E2F7_HUMAN Decreases Expression [8]
FGGY carbohydrate kinase domain-containing protein (FGGY) OTLNEC2X FGGY_HUMAN Increases Expression [8]
Inactive rhomboid protein 1 (RHBDF1) OTCQ7UDS RHDF1_HUMAN Increases Expression [8]
Isochorismatase domain-containing protein 1 (ISOC1) OTAO7Z87 ISOC1_HUMAN Decreases Expression [8]
Methyl-CpG-binding domain protein 6 (MBD6) OTDHBSFS MBD6_HUMAN Increases Expression [8]
Methionyl-tRNA formyltransferase, mitochondrial (MTFMT) OT1OIVJL FMT_HUMAN Decreases Expression [8]
Mitochondrial glycine transporter (SLC25A38) OTP4WXFU S2538_HUMAN Increases Expression [8]
Ribosome-recycling factor, mitochondrial (MRRF) OT6AHPVG RRFM_HUMAN Increases Expression [8]
RecQ-mediated genome instability protein 2 (RMI2) OTA0HP4S RMI2_HUMAN Decreases Expression [8]
Sperm acrosome-associated protein 9 (SPACA9) OTVRFX49 SACA9_HUMAN Increases Expression [8]
RNA-binding protein 33 (RBM33) OT4JQ9YG RBM33_HUMAN Increases Expression [8]
Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) OTUVR2OO DC2I2_HUMAN Decreases Expression [8]
DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3) OT61924T DNJA3_HUMAN Increases Expression [8]
AMSH-like protease (STAMBPL1) OTI4CYTF STALP_HUMAN Increases Expression [8]
Diphosphoinositol polyphosphate phosphohydrolase 3-beta (NUDT11) OTFDXJA1 NUD11_HUMAN Decreases Expression [8]
Chronophin (PDXP) OTZ7GN95 PLPP_HUMAN Decreases Expression [8]
Aurora kinase B (AURKB) OTIY4VHU AURKB_HUMAN Decreases Expression [8]
Cell division cycle-associated 7-like protein (CDCA7L) OT1FFWKC CDA7L_HUMAN Decreases Expression [8]
RUS family member 1 (RUSF1) OTRIIY6J RUSF1_HUMAN Increases Expression [8]
Serine/threonine-protein kinase greatwall (MASTL) OTQ7YKK5 GWL_HUMAN Decreases Expression [8]
Protein disulfide isomerase CRELD1 (CRELD1) OTBSPZFP CREL1_HUMAN Increases Expression [8]
Transcription cofactor HES-6 (HES6) OTWO5SCF HES6_HUMAN Decreases Expression [8]
Mannose-1-phosphate guanyltransferase alpha (GMPPA) OTADC03N GMPPA_HUMAN Increases Expression [8]
Conserved oligomeric Golgi complex subunit 3 (COG3) OTKJMB1Q COG3_HUMAN Increases Expression [8]
Coiled-coil domain-containing protein 74B (CCDC74B) OTTRSGJR CC74B_HUMAN Increases Expression [8]
Dynein heavy chain domain-containing protein 1 (DNHD1) OT4U3HUW DNHD1_HUMAN Increases Expression [8]
Protein phosphatase 1M (PPM1M) OTCPLZQ7 PPM1M_HUMAN Increases Expression [8]
Sideroflexin-2 (SFXN2) OTRFKK0G SFXN2_HUMAN Decreases Expression [8]
Methylmalonyl-CoA epimerase, mitochondrial (MCEE) OTTJP3GM MCEE_HUMAN Increases Expression [8]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Increases Expression [8]
Small integral membrane protein 14 (SMIM14) OT47IF19 SIM14_HUMAN Increases Expression [8]
Sperm-associated antigen 5 (SPAG5) OTCLJ56M SPAG5_HUMAN Decreases Expression [8]
Elongation factor G, mitochondrial (GFM1) OTUN4V3N EFGM_HUMAN Decreases Expression [8]
Tribbles homolog 3 (TRIB3) OTG5OS7X TRIB3_HUMAN Increases Expression [8]
Chloride channel CLIC-like protein 1 (CLCC1) OTTXCXVT CLCC1_HUMAN Increases Expression [8]
Protein phosphatase 1 regulatory inhibitor subunit 16B (PPP1R16B) OTZJFX5C PP16B_HUMAN Decreases Expression [8]
Insulinoma-associated protein 2 (INSM2) OTNMQUZV INSM2_HUMAN Decreases Expression [8]
c-Myc-binding protein (MYCBP) OT4IZR4R MYCBP_HUMAN Decreases Expression [8]
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) OTW258OV PSMD1_HUMAN Decreases Expression [8]
M-phase phosphoprotein 6 (MPHOSPH6) OT6E2S48 MPH6_HUMAN Decreases Expression [8]
Ribonucleases P/MRP protein subunit POP1 (POP1) OTBIYMJ0 POP1_HUMAN Decreases Expression [8]
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) OTYRXD2T PMYT1_HUMAN Decreases Expression [8]
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) OTC8G2MX C560_HUMAN Decreases Expression [8]
G-protein coupled receptor 22 (GPR22) OTHTSAJI GPR22_HUMAN Increases Expression [8]
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) OT7RJON4 HCD2_HUMAN Decreases Expression [8]
ATP synthase subunit s, mitochondrial (DMAC2L) OT2OQ1UD ATP5S_HUMAN Decreases Expression [8]
Transmembrane 9 superfamily member 2 (TM9SF2) OTA0C202 TM9S2_HUMAN Increases Expression [8]
Endothelial PAS domain-containing protein 1 (EPAS1) OTRE3O8U EPAS1_HUMAN Decreases Expression [8]
Growth/differentiation factor 15 (GDF15) OTWQN50N GDF15_HUMAN Increases Expression [8]
Protein NipSnap homolog 1 (NIPSNAP1) OTKXKUT8 NIPS1_HUMAN Decreases Expression [8]
Condensin complex subunit 3 (NCAPG) OT1AI9EO CND3_HUMAN Decreases Expression [8]
Ribosome quality control complex subunit TCF25 (TCF25) OTTFHHU9 TCF25_HUMAN Increases Expression [8]
La-related protein 6 (LARP6) OTUQ9QS9 LARP6_HUMAN Increases Expression [8]
Sugar transporter SWEET1 (SLC50A1) OTF1DT72 SWET1_HUMAN Increases Expression [8]
Endoplasmic reticulum resident protein 44 (ERP44) OT7ZI7AG ERP44_HUMAN Increases Expression [8]
Endosomal/lysosomal proton channel TMEM175 (TMEM175) OT6DUIYC TM175_HUMAN Increases Expression [8]
Protein PIMREG (PIMREG) OTKC8T3E PIMRE_HUMAN Decreases Expression [8]
Synaptotagmin-17 (SYT17) OTTW4MI3 SYT17_HUMAN Increases Expression [8]
Transmembrane protein 70, mitochondrial (TMEM70) OTLTKYXG TMM70_HUMAN Decreases Expression [8]
Brain-enriched guanylate kinase-associated protein (BEGAIN) OTT3UD2K BEGIN_HUMAN Decreases Expression [8]
Dual specificity protein phosphatase 26 (DUSP26) OTI7WIYN DUS26_HUMAN Increases Expression [8]
Protein adenylyltransferase FICD (FICD) OT2R9ZXW FICD_HUMAN Increases Expression [8]
Sister chromatid cohesion protein DCC1 (DSCC1) OTPUVLZT DCC1_HUMAN Decreases Expression [8]
Transmembrane emp24 domain-containing protein 9 (TMED9) OTYGAQS0 TMED9_HUMAN Increases Expression [8]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) OTZ092ZJ THIC_HUMAN Decreases Expression [8]
Cell division cycle-associated protein 7 (CDCA7) OT12HDZY CDCA7_HUMAN Decreases Expression [8]
Receptor for retinol uptake STRA6 (STRA6) OT2IDF27 STRA6_HUMAN Decreases Expression [8]
Rab11 family-interacting protein 5 (RAB11FIP5) OTNA33DE RFIP5_HUMAN Increases Expression [8]
Serine/threonine-protein kinase PINK1, mitochondrial (PINK1) OT50NR57 PINK1_HUMAN Increases Expression [8]
Nucleolar and spindle-associated protein 1 (NUSAP1) OT85HIJ5 NUSAP_HUMAN Decreases Expression [8]
Eukaryotic translation initiation factor 2A (EIF2A) OTWXELQP EIF2A_HUMAN Increases Expression [8]
Signal peptidase complex catalytic subunit SEC11C (SEC11C) OTP3WS0U SC11C_HUMAN Increases Expression [8]
Large ribosomal subunit protein uL13m (MRPL13) OT6D8Y9G RM13_HUMAN Decreases Expression [8]
Large ribosomal subunit protein uL1m (MRPL1) OT3YIQIA RM01_HUMAN Increases Expression [8]
Probable mitochondrial glutathione transporter SLC25A39 (SLC25A39) OTO7WA10 S2539_HUMAN Decreases Expression [8]
Derlin-2 (DERL2) OTI3TUUZ DERL2_HUMAN Increases Expression [8]
Protein FAM107B (FAM107B) OT5RG4J0 F107B_HUMAN Increases Expression [8]
Enkurin domain-containing protein 1 (ENKD1) OT5YE5D5 ENKD1_HUMAN Increases Expression [8]
Large ribosomal subunit protein uL18m (MRPL18) OTORKKYC RM18_HUMAN Decreases Expression [8]
Nucleotide exchange factor SIL1 (SIL1) OTDI85I5 SIL1_HUMAN Increases Expression [8]
Iron-sulfur cluster assembly enzyme ISCU (ISCU) OTSW6DQP ISCU_HUMAN Increases Expression [8]
Caspase recruitment domain-containing protein 9 (CARD9) OTJ81AWD CARD9_HUMAN Increases Expression [8]
Sodium-coupled neutral amino acid symporter 1 (SLC38A1) OTO3VD5E S38A1_HUMAN Increases Expression [8]
Diphthine methyl ester synthase (DPH5) OT9UKOPV DPH5_HUMAN Increases Expression [8]
Golgi resident protein GCP60 (ACBD3) OTMYNY7A GCP60_HUMAN Increases Expression [8]
Protein FAM83D (FAM83D) OTQWZ1UO FA83D_HUMAN Decreases Expression [8]
Ribosomal oxygenase 1 (RIOX1) OTN41QXP RIOX1_HUMAN Decreases Expression [8]
dCTP pyrophosphatase 1 (DCTPP1) OTP1GZYF DCTP1_HUMAN Decreases Expression [8]
Complex I assembly factor ACAD9, mitochondrial (ACAD9) OT4HITJ6 ACAD9_HUMAN Decreases Expression [8]
Mitochondrial glutamate carrier 1 (SLC25A22) OTQGVI1N GHC1_HUMAN Decreases Expression [8]
RecQ-mediated genome instability protein 1 (RMI1) OT1ZVTFL RMI1_HUMAN Decreases Expression [8]
GrpE protein homolog 1, mitochondrial (GRPEL1) OT8O00YJ GRPE1_HUMAN Decreases Expression [8]
Kinetochore protein Spc25 (SPC25) OTCAS0OH SPC25_HUMAN Decreases Expression [8]
Popeye domain-containing protein 2 (POPDC2) OTDAZSY5 POPD2_HUMAN Decreases Expression [8]
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) OTQDHSMI MCCB_HUMAN Decreases Expression [8]
Stromal cell-derived factor 2-like protein 1 (SDF2L1) OTE7JIO2 SDF2L_HUMAN Increases Expression [8]
Receptor-type tyrosine-protein phosphatase H (PTPRH) OTDUHQGF PTPRH_HUMAN Increases Expression [8]
Homeobox protein HMX1 (HMX1) OT65ZGE0 HMX1_HUMAN Decreases Expression [8]
ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3) OT2G3KCG ARFG3_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase CCNB1IP1 (CCNB1IP1) OTOTVMC8 CIP1_HUMAN Increases Expression [8]
Acyl-coenzyme A thioesterase 13 (ACOT13) OTWRUST1 ACO13_HUMAN Decreases Expression [8]
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) OTIK4I5R TIDC1_HUMAN Increases Expression [8]
Leucine zipper transcription factor-like protein 1 (LZTFL1) OTIEIOEW LZTL1_HUMAN Increases Expression [8]
Nectin-3 (NECTIN3) OTS8N7MK NECT3_HUMAN Increases Expression [8]
Dual specificity tyrosine-phosphorylation-regulated kinase 4 (DYRK4) OTO9ZBI5 DYRK4_HUMAN Increases Expression [8]
Diablo IAP-binding mitochondrial protein (DIABLO) OTHJ9MCZ DBLOH_HUMAN Increases Expression [8]
Sialic acid synthase (NANS) OTMQ2FUH SIAS_HUMAN Increases Expression [8]
Oligosaccharyltransferase complex subunit OSTC (OSTC) OTT0823Y OSTC_HUMAN Increases Expression [8]
Carbonic anhydrase-related protein 10 (CA10) OTC3N1F6 CAH10_HUMAN Decreases Expression [8]
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3) OTMEF544 SIR3_HUMAN Decreases Expression [8]
RNA-binding protein 12 (RBM12) OTQYZ3LQ RBM12_HUMAN Decreases Expression [8]
Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) OTORNUIF STAU2_HUMAN Decreases Expression [8]
Transmembrane protein 100 (TMEM100) OTRJ6OHY TM100_HUMAN Decreases Expression [8]
Fanconi anemia group I protein (FANCI) OTW8E3SC FANCI_HUMAN Decreases Expression [8]
Guanine nucleotide-binding protein-like 3-like protein (GNL3L) OTZYEFST GNL3L_HUMAN Increases Expression [8]
Histone chaperone ASF1B (ASF1B) OTKXX12I ASF1B_HUMAN Decreases Expression [8]
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB) OTXLLSIZ MCUB_HUMAN Decreases Expression [8]
Very long chain fatty acid elongase 2 (ELOVL2) OTDAF6U3 ELOV2_HUMAN Decreases Expression [8]
Voltage-dependent calcium channel subunit alpha-2/delta-2 (CACNA2D2) OTFJXVQQ CA2D2_HUMAN Decreases Expression [8]
Peptidyl-prolyl cis-trans isomerase FKBP11 (FKBP11) OTY2GC67 FKB11_HUMAN Increases Expression [8]
BET1-like protein (BET1L) OT5QVYBZ BET1L_HUMAN Increases Expression [8]
Large ribosomal subunit protein bL35m (MRPL35) OT85WBWJ RM35_HUMAN Decreases Expression [8]
Denticleless protein homolog (DTL) OTC29RYE DTL_HUMAN Decreases Expression [8]
Ubiquinone biosynthesis O-methyltransferase, mitochondrial (COQ3) OTSGT89T COQ3_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) OT0UOKIT NDUAD_HUMAN Decreases Expression [8]
Armadillo repeat-containing X-linked protein 1 (ARMCX1) OTOGL58Z ARMX1_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase MARCHF4 (MARCHF4) OTK43VNA MARH4_HUMAN Decreases Expression [8]
A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) OTV3Q0DS ATS9_HUMAN Decreases Expression [8]
Kelch-like protein 13 (KLHL13) OTUNG578 KLH13_HUMAN Decreases Expression [8]
7-dehydrocholesterol reductase (DHCR7) OTLILBUI DHCR7_HUMAN Decreases Expression [8]
Voltage-dependent calcium channel gamma-4 subunit (CACNG4) OTE70DMK CCG4_HUMAN Decreases Expression [8]
Mitochondrial dicarboxylate carrier (SLC25A10) OTT8647H DIC_HUMAN Decreases Expression [8]
Mitochondrial fission process protein 1 (MTFP1) OT3L6F7U MTFP1_HUMAN Decreases Expression [8]
Translocation protein SEC63 homolog (SEC63) OT1ICPMK SEC63_HUMAN Increases Expression [8]
Solute carrier family 2, facilitated glucose transporter member 6 (SLC2A6) OTVUZCLG GTR6_HUMAN Decreases Expression [8]
Armadillo repeat-containing X-linked protein 3 (ARMCX3) OTMG7RWW ARMX3_HUMAN Increases Expression [8]
Transcription factor COE1 (EBF1) OTZ61YYH COE1_HUMAN Decreases Expression [8]
Contactin-associated protein-like 2 (CNTNAP2) OT48T2ZP CNTP2_HUMAN Increases Expression [8]
NADH dehydrogenase 1 alpha subcomplex subunit 12 (NDUFA12) OTCD6I5M NDUAC_HUMAN Decreases Expression [8]
Transgelin-3 (TAGLN3) OTJBP3VJ TAGL3_HUMAN Decreases Expression [8]
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) OTM59ZGG KAD3_HUMAN Decreases Expression [8]
Regulating synaptic membrane exocytosis protein 3 (RIMS3) OTHN3H0A RIMS3_HUMAN Increases Expression [8]
Lysosome-associated membrane glycoprotein 5 (LAMP5) OTC672RM LAMP5_HUMAN Decreases Expression [8]
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) OTTZVSK6 S2513_HUMAN Decreases Expression [8]
Drebrin-like protein (DBNL) OTT2OQOV DBNL_HUMAN Decreases Expression [8]
Cell cycle progression protein 1 (CCPG1) OT0IHDKL CCPG1_HUMAN Increases Expression [8]
Protein timeless homolog (TIMELESS) OTD8DCBJ TIM_HUMAN Decreases Expression [8]
Exonuclease 1 (EXO1) OTI87RS5 EXO1_HUMAN Decreases Expression [8]
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C) OTEU05TX PPR3C_HUMAN Decreases Expression [8]
Histone deacetylase 5 (HDAC5) OTWG387P HDAC5_HUMAN Increases Expression [8]
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (PIN4) OT403QC1 PIN4_HUMAN Decreases Expression [8]
Transcription factor 19 (TCF19) OT7NKLF9 TCF19_HUMAN Decreases Expression [8]
DNA replication complex GINS protein PSF2 (GINS2) OT974IYI PSF2_HUMAN Decreases Expression [8]
Carbonic anhydrase 5B, mitochondrial (CA5B) OTCIMJ8E CAH5B_HUMAN Increases Expression [8]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5) OT03QCLM ATF5_HUMAN Increases Expression [8]
GDP-fucose protein O-fucosyltransferase 2 (POFUT2) OT1MNJFZ OFUT2_HUMAN Increases Expression [8]
Netrin-G1 (NTNG1) OTF48IID NTNG1_HUMAN Increases Expression [8]
Small ribosomal subunit protein bS1m (MRPS28) OT8CLJ6M RT28_HUMAN Decreases Expression [8]
Calcium-regulated heat-stable protein 1 (CARHSP1) OTAUG6Y9 CHSP1_HUMAN Decreases Expression [8]
Conserved oligomeric Golgi complex subunit 6 (COG6) OTDLQITC COG6_HUMAN Increases Expression [8]
DNA-directed RNA polymerase III subunit RPC10 (POLR3K) OTZCSF6A RPC10_HUMAN Decreases Expression [8]
Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1) OTYK9JU6 CIA30_HUMAN Decreases Expression [8]
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2) OTURGRA8 MSRB2_HUMAN Increases Expression [8]
Dystrobrevin alpha (DTNA) OTVBIRH2 DTNA_HUMAN Decreases Expression [8]
Hypoxia up-regulated protein 1 (HYOU1) OTBGBSOV HYOU1_HUMAN Increases Expression [8]
Sorting and assembly machinery component 50 homolog (SAMM50) OTRYFYIU SAM50_HUMAN Increases Expression [8]
DNA-directed RNA polymerase III subunit RPC8 (POLR3H) OT7GM7MX RPC8_HUMAN Decreases Expression [8]
Peptidyl-prolyl cis-trans isomerase A-like 4A (PPIAL4A) OTJTMY5T PAL4A_HUMAN Decreases Expression [8]
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) OTJMHX1V TIM22_HUMAN Decreases Expression [8]
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) OTJQL0I3 HEY1_HUMAN Decreases Expression [8]
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) OTK7PDNN TIM9_HUMAN Increases Expression [8]
Signal recognition particle receptor subunit beta (SRPRB) OTUUFHQS SRPRB_HUMAN Increases Expression [8]
Fatty acid desaturase 3 (FADS3) OT9RVXGE FADS3_HUMAN Increases Expression [8]
Sorting nexin-10 (SNX10) OT05B7BT SNX10_HUMAN Decreases Expression [8]
Beta-1,3-N-acetylglucosaminyltransferase radical fringe (RFNG) OTWAN10O RFNG_HUMAN Increases Expression [8]
Dolichyl-phosphate beta-glucosyltransferase (ALG5) OT006CEI ALG5_HUMAN Increases Expression [8]
Small ribosomal subunit protein mS40 (MRPS18B) OT1K9PFX RT18B_HUMAN Increases Expression [8]
Coatomer subunit gamma-1 (COPG1) OT2NLQVH COPG1_HUMAN Increases Expression [8]
Glucocorticoid modulatory element-binding protein 1 (GMEB1) OT4F8RFH GMEB1_HUMAN Decreases Expression [8]
LHFPL tetraspan subfamily member 6 protein (LHFPL6) OTY6LHJY LHPL6_HUMAN Increases Expression [8]
Mitochondrial carrier homolog 2 (MTCH2) OTV3E4GU MTCH2_HUMAN Decreases Expression [8]
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) OTO3WI7S NDUB9_HUMAN Decreases Expression [8]
Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) OT0N3WL9 COX11_HUMAN Increases Expression [8]
Stress-associated endoplasmic reticulum protein 1 (SERP1) OT60XXUP SERP1_HUMAN Increases Expression [8]
Ret finger protein-like 4A (RFPL4A) OTROUM09 RFPLA_HUMAN Increases Expression [9]
Interferon-related developmental regulator 1 (IFRD1) OT4SQMLQ IFRD1_HUMAN Increases Expression [9]
CCN family member 1 (CCN1) OTKJBEMD CCN1_HUMAN Increases Expression [9]
Laminin subunit alpha-5 (LAMA5) OTIIXE4M LAMA5_HUMAN Decreases Expression [9]
Beta-1,4-galactosyltransferase 5 (B4GALT5) OTHMZY12 B4GT5_HUMAN Increases Expression [9]
Mothers against decapentaplegic homolog 6 (SMAD6) OTUZZWUD SMAD6_HUMAN Decreases Expression [9]
Galanin receptor type 2 (GALR2) OTNJBJC1 GALR2_HUMAN Increases Expression [9]
Acyl-CoA (FADS1) OTUYOYHX FADS1_HUMAN Increases Expression [9]
Integral membrane protein GPR137B (GPR137B) OT1CINQQ G137B_HUMAN Decreases Expression [9]
Forkhead box protein D2 (FOXD2) OTAF63YV FOXD2_HUMAN Decreases Expression [9]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B) OTL9I7LO GA45B_HUMAN Increases Expression [9]
Lathosterol oxidase (SC5D) OT41KMW4 SC5D_HUMAN Increases Expression [9]
Retinal dehydrogenase 2 (ALDH1A2) OTJB560Z AL1A2_HUMAN Decreases Expression [9]
Serine protease 23 (PRSS23) OT6DQAM1 PRS23_HUMAN Increases Expression [9]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G) OT8V1J4M GA45G_HUMAN Increases Expression [9]
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2) OTDLEXPN PAPS2_HUMAN Decreases Expression [9]
Lymphocyte antigen 6 complex locus protein G6d (LY6G6D) OTG75QOC LY66D_HUMAN Decreases Expression [9]
Ubiquitin-like protein ISG15 (ISG15) OT53QQ7N ISG15_HUMAN Increases Expression [9]
Alkaline phosphatase, placental type (ALPP) OTZU4G9W PPB1_HUMAN Increases Expression [9]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Increases Expression [9]
Alpha-galactosidase A (GLA) OTBSR6DT AGAL_HUMAN Increases Expression [9]
Lipoprotein lipase (LPL) OTTW0267 LIPL_HUMAN Increases Expression [9]
Asialoglycoprotein receptor 1 (ASGR1) OTS99MJO ASGR1_HUMAN Increases Expression [9]
Keratin, type I cytoskeletal 19 (KRT19) OTDGDQ75 K1C19_HUMAN Decreases Expression [9]
U1 small nuclear ribonucleoprotein A (SNRPA) OT02TSQT SNRPA_HUMAN Decreases Expression [9]
Homeobox protein Hox-B5 (HOXB5) OTU74TB8 HXB5_HUMAN Decreases Expression [9]
Gamma-enolase (ENO2) OTRODL0T ENOG_HUMAN Increases Expression [9]
Retinol-binding protein 1 (RBP1) OTRP1MFC RET1_HUMAN Decreases Expression [9]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Increases Expression [9]
Calcitonin gene-related peptide 2 (CALCB) OTNVY7WY CALCB_HUMAN Increases Expression [9]
COUP transcription factor 1 (NR2F1) OTGWZWYL COT1_HUMAN Decreases Expression [9]
Ras-related protein Ral-B (RALB) OTFH203X RALB_HUMAN Decreases Expression [9]
Cytochrome b-245 light chain (CYBA) OT16N9ZO CY24A_HUMAN Decreases Expression [9]
CD44 antigen (CD44) OT9TTJ41 CD44_HUMAN Increases Expression [9]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) OTGVC9MY PLCG2_HUMAN Decreases Expression [9]
Transcription factor JunD (JUND) OTNKACJD JUND_HUMAN Increases Expression [9]
Protachykinin-1 (TAC1) OTM842YW TKN1_HUMAN Increases Expression [9]
Collagen alpha-1(V) chain (COL5A1) OT24078H CO5A1_HUMAN Decreases Expression [9]
Insulin-like growth factor-binding protein 5 (IGFBP5) OTRE5V0C IBP5_HUMAN Decreases Expression [9]
Dual specificity protein phosphatase 1 (DUSP1) OTN6BR75 DUS1_HUMAN Increases Expression [9]
Homeobox protein Hox-A10 (HOXA10) OTB6GQ09 HXA10_HUMAN Decreases Expression [9]
Homeobox protein Hox-A13 (HOXA13) OTTRI3KI HXA13_HUMAN Decreases Expression [9]
Homeobox protein Hox-C8 (HOXC8) OTJUYU8J HXC8_HUMAN Decreases Expression [9]
Homeobox protein Hox-C9 (HOXC9) OT60K4M0 HXC9_HUMAN Decreases Expression [9]
Homeobox protein Hox-C13 (HOXC13) OT52AVNA HXC13_HUMAN Decreases Expression [9]
ETS-related transcription factor Elf-1 (ELF1) OTV5LKIA ELF1_HUMAN Increases Expression [9]
Cystathionine gamma-lyase (CTH) OTC90LA0 CGL_HUMAN Increases Expression [9]
CD70 antigen (CD70) OTHB2AL1 CD70_HUMAN Increases Expression [9]
Fibrillin-2 (FBN2) OT3KYJQL FBN2_HUMAN Increases Expression [9]
Metalloproteinase inhibitor 3 (TIMP3) OTDGQAD1 TIMP3_HUMAN Increases Expression [9]
Transcription factor SOX-18 (SOX18) OTPUMHWA SOX18_HUMAN Decreases Expression [9]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [9]
Pre-B-cell leukemia transcription factor 3 (PBX3) OT8WMVM4 PBX3_HUMAN Decreases Expression [9]
Regulator of G-protein signaling 2 (RGS2) OT0FSRW7 RGS2_HUMAN Increases Expression [9]
Beta-crystallin B2 (CRYBB2) OTL0Z8E6 CRBB2_HUMAN Increases Expression [9]
LIM/homeobox protein Lhx2 (LHX2) OTK61NP8 LHX2_HUMAN Decreases Expression [9]
Calcipressin-1 (RCAN1) OT1MVXC7 RCAN1_HUMAN Increases Expression [9]
Myomesin-2 (MYOM2) OTD2UOXW MYOM2_HUMAN Decreases Expression [9]
Growth arrest-specific protein 1 (GAS1) OTKJXG52 GAS1_HUMAN Increases Expression [9]
Proteinase-activated receptor 2 (F2RL1) OTMRMJ8N PAR2_HUMAN Increases Expression [9]
Ras-related protein Rab-38 (RAB38) OTU0NZU0 RAB38_HUMAN Decreases Expression [9]
Cortexin-1 (CTXN1) OTQQ9UBY CTXN1_HUMAN Decreases Expression [9]
Protein S100-A10 (S100A10) OTI71243 S10AA_HUMAN Decreases Expression [9]
Signal peptidase complex subunit 3 (SPCS3) OTAPFSUQ SPCS3_HUMAN Increases Expression [9]
ADP-ribosylation factor 3 (ARF3) OTYYQX85 ARF3_HUMAN Decreases Expression [9]
Osteocrin (OSTN) OTL4A57N OSTN_HUMAN Increases Expression [9]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Decreases Expression [9]
Iroquois-class homeodomain protein IRX-3 (IRX3) OTLJ48FG IRX3_HUMAN Decreases Expression [9]
Forkhead box protein O4 (FOXO4) OT90X9LN FOXO4_HUMAN Decreases Expression [9]
DNA-binding protein inhibitor ID-3 (ID3) OTUULW5Z ID3_HUMAN Decreases Expression [9]
Transforming growth factor beta receptor type 3 (TGFBR3) OTQOOUC4 TGBR3_HUMAN Decreases Expression [9]
Activin receptor type-1 (ACVR1) OT4JATFE ACVR1_HUMAN Increases Expression [9]
Cingulin-like protein 1 (CGNL1) OTRE9DGT CGNL1_HUMAN Decreases Expression [9]
Nucleoside diphosphate kinase 3 (NME3) OT0CA0GF NDK3_HUMAN Decreases Expression [9]
Syntaxin-3 (STX3) OT4CIWLJ STX3_HUMAN Increases Expression [9]
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1) OTHBQVD5 4EBP1_HUMAN Increases Expression [9]
Ras-related protein Rab-31 (RAB31) OTMLXQZ0 RAB31_HUMAN Decreases Expression [9]
Cold-inducible RNA-binding protein (CIRBP) OTXWTPBL CIRBP_HUMAN Increases Expression [9]
Flotillin-2 (FLOT2) OTZ0QR5L FLOT2_HUMAN Decreases Expression [9]
Transcription factor HES-1 (HES1) OT8P19W2 HES1_HUMAN Decreases Expression [9]
Phosphatidate phosphatase LPIN1 (LPIN1) OTQ75KF2 LPIN1_HUMAN Increases Expression [9]
CCAAT/enhancer-binding protein epsilon (CEBPE) OTKZA25M CEBPE_HUMAN Increases Expression [9]
Alpha-internexin (INA) OT1D33T4 AINX_HUMAN Increases Expression [9]
Nuclear factor interleukin-3-regulated protein (NFIL3) OTQH9HM3 NFIL3_HUMAN Increases Expression [9]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Increases Expression [9]
Dual specificity protein phosphatase 5 (DUSP5) OTH96RA7 DUS5_HUMAN Decreases Expression [9]
Histone H2A type 2-C (H2AC20) OTEIVLM1 H2A2C_HUMAN Increases Expression [9]
SKI/DACH domain-containing protein 1 (SKIDA1) OTI3EOET SKDA1_HUMAN Decreases Expression [9]
MHC class I polypeptide-related sequence B (MICB) OTS2DVDW MICB_HUMAN Increases Expression [9]
Keratin-associated protein 21-2 (KRTAP21-2) OT1JVP79 KR212_HUMAN Increases Expression [9]
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 (ITPRIPL2) OTSSP13W IPIL2_HUMAN Decreases Expression [9]
Membrane protein FAM174B (FAM174B) OT1SCOTY F174B_HUMAN Increases Expression [9]
Angiomotin (AMOT) OTWHDG9B AMOT_HUMAN Decreases Expression [9]
Protein LBH (LBH) OT87AT1X LBH_HUMAN Increases Expression [9]
Metaxin-3 (MTX3) OTFYDBAT MTX3_HUMAN Increases Expression [9]
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EARS2) OTNCJKY7 SYEM_HUMAN Decreases Expression [9]
RRP12-like protein (RRP12) OTQQAEH4 RRP12_HUMAN Increases Expression [9]
Uncharacterized protein C6orf141 (C6ORF141) OTUS3SIQ CF141_HUMAN Increases Expression [9]
Mitochondrial amidoxime-reducing component 1 (MTARC1) OTNBE033 MARC1_HUMAN Decreases Expression [9]
Muscleblind-like protein 2 (MBNL2) OTF7CF1F MBNL2_HUMAN Increases Expression [9]
Protein sel-1 homolog 3 (SEL1L3) OT10N6Z2 SE1L3_HUMAN Increases Expression [9]
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) OTQ0QH1P TTC19_HUMAN Increases Expression [9]
Histone H2A type 2-A (H2AC18) OTCE5JC7 H2A2A_HUMAN Increases Expression [9]
Endoplasmic reticulum aminopeptidase 2 (ERAP2) OTEMENYF ERAP2_HUMAN Decreases Expression [9]
Glucose 1,6-bisphosphate synthase (PGM2L1) OTSBNRT5 PGM2L_HUMAN Increases Expression [9]
Prostate androgen-regulated mucin-like protein 1 (PARM1) OTDNK7EX PARM1_HUMAN Increases Expression [9]
Protein shisa-2 homolog (SHISA2) OT4GMTML SHSA2_HUMAN Increases Expression [9]
Dehydrogenase/reductase SDR family member 13 (DHRS13) OT45VM0J DHR13_HUMAN Increases Expression [9]
Serine/threonine-protein kinase TAO1 (TAOK1) OTFFLV6Q TAOK1_HUMAN Increases Expression [9]
Uncharacterized protein C11orf96 (C11ORF96) OTEQU0V7 CK096_HUMAN Increases Expression [9]
Epoxide hydrolase 4 (EPHX4) OTMLVHIH EPHX4_HUMAN Increases Expression [9]
L-seryl-tRNA(Sec) kinase (PSTK) OTA5UXAX PSTK_HUMAN Increases Expression [9]
Cytochrome P450 4X1 (CYP4X1) OTMTEUNE CP4X1_HUMAN Increases Expression [9]
Reprimo-like protein (RPRML) OTPOESFN RPRML_HUMAN Decreases Expression [9]
Macoilin (MACO1) OTT9W0BR MACOI_HUMAN Increases Expression [9]
Centrosomal protein POC5 (POC5) OTHD4FIH POC5_HUMAN Increases Expression [9]
Testis-expressed protein 19 (TEX19) OTY6MIZ9 TEX19_HUMAN Increases Expression [9]
Transmembrane protein C1orf162 (C1ORF162) OT6TC9TZ CA162_HUMAN Increases Expression [9]
Nuclear receptor coactivator 7 (NCOA7) OT2CNBOG NCOA7_HUMAN Increases Expression [9]
Solute carrier family 35 member G2 (SLC35G2) OTFBVS0P S35G2_HUMAN Increases Expression [9]
Serine/threonine-protein kinase BRSK1 (BRSK1) OT6N35Q0 BRSK1_HUMAN Increases Expression [9]
Probable glutathione peroxidase 8 (GPX8) OTTH80PN GPX8_HUMAN Increases Expression [9]
Sodium-dependent phosphate transporter 1 (SLC20A1) OTC3D894 S20A1_HUMAN Increases Expression [9]
Protein NDRG1 (NDRG1) OTVO66BO NDRG1_HUMAN Increases Expression [9]
Peroxidasin homolog (PXDN) OTFGGM9R PXDN_HUMAN Increases Expression [9]
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) OT1IK0KA VPP1_HUMAN Increases Expression [9]
Repulsive guidance molecule A (RGMA) OTZAMDO2 RGMA_HUMAN Decreases Expression [9]
TLC domain-containing protein 1 (TLCD1) OTD2VADH TLCD1_HUMAN Increases Expression [9]
THAP domain-containing protein 11 (THAP11) OTEMWLZ0 THA11_HUMAN Decreases Expression [9]
Serine dehydratase-like (SDSL) OTGZEAGJ SDSL_HUMAN Increases Expression [9]
DDRGK domain-containing protein 1 (DDRGK1) OT3KCK0U DDRGK_HUMAN Increases Expression [9]
CDK5 regulatory subunit-associated protein 3 (CDK5RAP3) OTC0Q2QS CK5P3_HUMAN Increases Expression [9]
RING finger protein 145 (RNF145) OTBCTG4A RN145_HUMAN Increases Expression [9]
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) OTALABSK S38A2_HUMAN Increases Expression [9]
Germ cell nuclear acidic protein (GCNA) OTIU3F9Y GCNA_HUMAN Increases Expression [9]
Tribbles homolog 1 (TRIB1) OTPEO17G TRIB1_HUMAN Increases Expression [9]
Cysteine/serine-rich nuclear protein 1 (CSRNP1) OTDK1FPH CSRN1_HUMAN Increases Expression [9]
Transmembrane protein 209 (TMEM209) OTH9U9U1 TM209_HUMAN Increases Expression [9]
Proheparin-binding EGF-like growth factor (HBEGF) OTLU00JS HBEGF_HUMAN Increases Expression [9]
Sialidase-1 (NEU1) OTH9BY8Y NEUR1_HUMAN Increases Expression [9]
TSC22 domain family protein 3 (TSC22D3) OT03UM03 T22D3_HUMAN Increases Expression [9]
Protein C10 (C12ORF57) OT7V1MLD C10_HUMAN Increases Expression [9]
Selenoprotein S (SELENOS) OTUEWIU9 SELS_HUMAN Increases Expression [9]
Mesoderm posterior protein 1 (MESP1) OTY5QDBN MESP1_HUMAN Increases Expression [9]
Transmembrane protein 79 (TMEM79) OTEC6EFU TMM79_HUMAN Increases Expression [9]
Synaptotagmin-11 (SYT11) OTLRTZEI SYT11_HUMAN Increases Expression [9]
MAPK regulated corepressor interacting protein 2 (MCRIP2) OTAJR36W MCRI2_HUMAN Decreases Expression [9]
EMILIN-2 (EMILIN2) OTOYK5A8 EMIL2_HUMAN Increases Expression [9]
Protein BEX2 (BEX2) OT4G5SIC BEX2_HUMAN Increases Expression [9]
Cell adhesion molecule 1 (CADM1) OTRWG9QS CADM1_HUMAN Decreases Expression [9]
Tripartite motif-containing protein 2 (TRIM2) OT0V1YVC TRIM2_HUMAN Increases Expression [9]
Potassium channel subfamily K member 12 (KCNK12) OTFP82TK KCNKC_HUMAN Increases Expression [9]
Protein S100-A14 (S100A14) OTVFJJ91 S10AE_HUMAN Increases Expression [9]
Serine--tRNA ligase, mitochondrial (SARS2) OTU4T99W SYSM_HUMAN Increases Expression [9]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) OT5V52LN TNR12_HUMAN Increases Expression [9]
Cartilage acidic protein 1 (CRTAC1) OT4PGEVE CRAC1_HUMAN Increases Expression [9]
Cell death regulator Aven (AVEN) OTGIN5YK AVEN_HUMAN Increases Expression [9]
NEDD4 family-interacting protein 2 (NDFIP2) OT34DCAP NFIP2_HUMAN Increases Expression [9]
Transmembrane protein 160 (TMEM160) OTWVIV7I TM160_HUMAN Decreases Expression [9]
Ankyrin repeat domain-containing protein 10 (ANKRD10) OTIZ2VK8 ANR10_HUMAN Increases Expression [9]
Protein FAM13B (FAM13B) OTNQTYSM FA13B_HUMAN Increases Expression [9]
Cingulin (CGN) OTBCQ8AQ CING_HUMAN Decreases Expression [9]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (GNG12) OTOGF42G GBG12_HUMAN Decreases Expression [9]
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) OTOSRDJT TR10D_HUMAN Increases Expression [9]
Nuclear RNA export factor 1 (NXF1) OTEFHXG6 NXF1_HUMAN Increases Expression [9]
NADH-cytochrome b5 reductase 1 (CYB5R1) OTMDHMLA NB5R1_HUMAN Increases Expression [9]
SERTA domain-containing protein 1 (SERTAD1) OTBHKZQP SRTD1_HUMAN Increases Expression [9]
Prenylated Rab acceptor protein 1 (RABAC1) OTGB32NG PRAF1_HUMAN Increases Expression [9]
Beta-citrylglutamate synthase B (RIMKLB) OT27A1MS RIMKB_HUMAN Increases Expression [9]
Protein PHTF1 (PHTF1) OTYCZ84A PHTF1_HUMAN Increases Expression [9]
Cystine/glutamate transporter (SLC7A11) OTKJ6PXW XCT_HUMAN Increases Expression [9]
Ribosome maturation protein SBDS (SBDS) OTHDCCIB SBDS_HUMAN Increases Expression [9]
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) OTJBDX0Y VPP2_HUMAN Increases Expression [9]
Retinoic acid-induced protein 2 (RAI2) OTR8LX4J RAI2_HUMAN Decreases Expression [9]
Dynamin-1-like protein (DNM1L) OTXK1Q1G DNM1L_HUMAN Increases Expression [17]
Transmembrane protease serine 2 (TMPRSS2) OTN44YQ5 TMPS2_HUMAN Decreases Expression [18]
Calumenin (CALU) OTSYQN71 CALU_HUMAN Decreases Expression [10]
Dynamin-like 120 kDa protein, mitochondrial (OPA1) OTJGNWPW OPA1_HUMAN Increases Expression [17]
Nuclear protein 1 (NUPR1) OT4FU8C0 NUPR1_HUMAN Increases Expression [19]
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) OTRNDZXB HNRPQ_HUMAN Affects Localization [20]
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) OTT00T7Q PLOD3_HUMAN Decreases Expression [10]
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1) OTY9R6FZ ERN1_HUMAN Increases Expression [21]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Decreases Expression [22]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) OTYG179K PR15A_HUMAN Increases Expression [23]
Ribosomal L1 domain-containing protein 1 (RSL1D1) OT3CL4R3 RL1D1_HUMAN Affects Expression [24]
Mitofusin-2 (MFN2) OTPYN8A3 MFN2_HUMAN Increases Expression [17]
Alpha-1-antitrypsin (SERPINA1) OTACYW9J A1AT_HUMAN Increases Expression [10]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [24]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Increases Expression [25]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Increases Expression [26]
Keratin, type II cytoskeletal 6A (KRT6A) OT392M5T K2C6A_HUMAN Decreases Expression [10]
Apolipoprotein C-III (APOC3) OTW3520C APOC3_HUMAN Decreases Expression [27]
Apolipoprotein B-100 (APOB) OTH0UOCZ APOB_HUMAN Decreases Expression [27]
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) OTTO6ZP4 AT1B1_HUMAN Increases Expression [28]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) OTM0GDTP IF2A_HUMAN Increases Expression [29]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Increases Expression [25]
Keratin, type II cytoskeletal 8 (KRT8) OTTM4X11 K2C8_HUMAN Decreases Expression [10]
Prostate-specific antigen (KLK3) OTFGSBFJ KLK3_HUMAN Decreases Expression [18]
Complement decay-accelerating factor (CD55) OTZ3HWTO DAF_HUMAN Increases Expression [24]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Decreases Expression [30]
5-hydroxytryptamine receptor 1A (HTR1A) OT38K9MK 5HT1A_HUMAN Increases Activity [31]
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) OTIRPN6B ROA1_HUMAN Affects Localization [32]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Increases Expression [25]
Endoplasmic reticulum chaperone BiP (HSPA5) OTFUIRAO BIP_HUMAN Increases Expression [11]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Increases Expression [25]
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) OTPGAU0U AT2A2_HUMAN Increases Expression [33]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Increases Expression [34]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Increases Expression [35]
Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) OTAFHAVI ATF6A_HUMAN Increases Expression [21]
Kallikrein-2 (KLK2) OT9RE37R KLK2_HUMAN Decreases Expression [18]
Protein EVI2A (EVI2A) OTR8RUXQ EVI2A_HUMAN Increases Expression [24]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Decreases Expression [34]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Increases Expression [34]
Tumor necrosis factor receptor superfamily member 6 (FAS) OTP9XG86 TNR6_HUMAN Increases Expression [28]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Increases Phosphorylation [13]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Increases Phosphorylation [13]
Caspase-1 (CASP1) OTZ3YQFU CASP1_HUMAN Increases Expression [26]
Protein disulfide-isomerase A3 (PDIA3) OTHPQ0Q3 PDIA3_HUMAN Increases Expression [36]
Pro-adrenomedullin (ADM) OT7T0TA4 ADML_HUMAN Decreases Expression [37]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Increases Expression [38]
Breast cancer type 1 susceptibility protein (BRCA1) OT5BN6VH BRCA1_HUMAN Increases Expression [39]
Hepatocyte nuclear factor 4-alpha (HNF4A) OTY1TOAB HNF4A_HUMAN Decreases Expression [22]
Tumor necrosis factor ligand superfamily member 9 (TNFSF9) OTV9L89D TNFL9_HUMAN Increases Expression [24]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Increases Activity [40]
Caspase-2 (CASP2) OTUDYSPP CASP2_HUMAN Increases Activity [41]
Large ribosomal subunit protein uL15 (RPL27A) OTQQHPL0 RL27A_HUMAN Affects Expression [24]
Protein ERGIC-53 (LMAN1) OTYHKDEO LMAN1_HUMAN Increases Expression [42]
Breast cancer type 2 susceptibility protein (BRCA2) OTF1XSV1 BRCA2_HUMAN Increases Expression [39]
Microsomal triglyceride transfer protein large subunit (MTTP) OTNUVSDT MTP_HUMAN Decreases Expression [27]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Increases Activity [40]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Increases Activity [41]
Gem-associated protein 4 (GEMIN4) OTX7402E GEMI4_HUMAN Decreases Expression [24]
Gasdermin-D (GSDMD) OTH39BKI GSDMD_HUMAN Increases Expression [26]
Inhibin beta E chain (INHBE) OTOI2NYG INHBE_HUMAN Increases Expression [43]
Lysozyme C (LYZ) OTD7H0G6 LYSC_HUMAN Increases Secretion [44]
Neutrophil gelatinase-associated lipocalin (LCN2) OTSB42BR NGAL_HUMAN Increases Expression [45]
Protein SET (SET) OTGYYQJO SET_HUMAN Decreases Expression [10]
Early activation antigen CD69 (CD69) OTGJHSVP CD69_HUMAN Increases Expression [24]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Increases Activity [46]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Increases Expression [47]
Protein phosphatase 3 catalytic subunit alpha (PPP3CA) OT58PUEN PP2BA_HUMAN Increases Expression [21]
DnaJ homolog subfamily C member 3 (DNAJC3) OT7ROIJF DNJC3_HUMAN Increases Expression [23]
Eukaryotic translation initiation factor 3 subunit I (EIF3I) OTE07WND EIF3I_HUMAN Decreases Expression [10]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Increases Expression [13]
Nascent polypeptide-associated complex subunit alpha (NACA) OTLP1KR3 NACA_HUMAN Decreases Expression [10]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) OTXEE550 APR_HUMAN Increases Expression [48]
Exosome complex component RRP4 (EXOSC2) OTN6NVKL EXOS2_HUMAN Decreases Expression [24]
Interleukin-18 (IL18) OTBB2A8O IL18_HUMAN Increases Expression [26]
Kelch-like ECH-associated protein 1 (KEAP1) OTFHOD0C KEAP1_HUMAN Increases Expression [49]
Reticulocalbin-2 (RCN2) OTIU8JWD RCN2_HUMAN Decreases Expression [10]
Nucleolar and coiled-body phosphoprotein 1 (NOLC1) OTKDZU0D NOLC1_HUMAN Decreases Expression [24]
Exosome complex component RRP42 (EXOSC7) OTCGRKNK EXOS7_HUMAN Affects Expression [24]
Rho-related GTP-binding protein RhoH (RHOH) OT1J9SEB RHOH_HUMAN Decreases Expression [24]
Cyclin-G2 (CCNG2) OTII38K2 CCNG2_HUMAN Increases Expression [34]
Transcriptional protein SWT1 (SWT1) OTY4AFM1 SWT1_HUMAN Decreases Expression [28]
Myomegalin (PDE4DIP) OTS15WNF MYOME_HUMAN Increases Expression [24]
Inactive caspase-12 (CASP12) OTY2W6FG CASPC_HUMAN Increases Activity [29]
Mitofusin-1 (MFN1) OTCBXQZF MFN1_HUMAN Increases Expression [17]
DnaJ homolog subfamily C member 10 (DNAJC10) OTD2EG0R DJC10_HUMAN Increases Expression [36]
Transmembrane protein 87A (TMEM87A) OT8ATDVX TM87A_HUMAN Increases Expression [28]
Programmed cell death 6-interacting protein (PDCD6IP) OTS8T6A7 PDC6I_HUMAN Increases Expression [10]
Sec1 family domain-containing protein 1 (SCFD1) OTN4T7JI SCFD1_HUMAN Decreases Expression [10]
CREB-binding protein (CREBBP) OTPA4QGM CBP_HUMAN Increases Expression [24]
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) OT2JHIHM CR3L1_HUMAN Increases Activity [50]
ERO1-like protein alpha (ERO1A) OTVKOQWM ERO1A_HUMAN Increases Expression [51]
DnaJ homolog subfamily C member 1 (DNAJC1) OTCKFOZ0 DNJC1_HUMAN Affects Expression [24]
Bcl-2-modifying factor (BMF) OT90NSLI BMF_HUMAN Decreases Expression [28]
NACHT, LRR and PYD domains-containing protein 3 (NLRP3) OTZM6MHU NLRP3_HUMAN Increases Expression [26]
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) OTVFRL8G TI17A_HUMAN Increases Expression [52]
Copine-1 (CPNE1) OTH5YKSL CPNE1_HUMAN Decreases Expression [10]
COP9 signalosome complex subunit 4 (COPS4) OTNK2KS1 CSN4_HUMAN Decreases Expression [10]
Transcription regulator protein BACH2 (BACH2) OT17GS18 BACH2_HUMAN Increases Expression [24]
Fibroblast growth factor 21 (FGF21) OT3RXVRD FGF21_HUMAN Increases Expression [53]
Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) OT0DZGY4 E2AK3_HUMAN Increases Expression [21]
DnaJ homolog subfamily B member 9 (DNAJB9) OT38EQT6 DNJB9_HUMAN Increases Expression [23]
Apoptosis-associated speck-like protein containing a CARD (PYCARD) OT67RON3 ASC_HUMAN Increases Expression [26]
Lactosylceramide alpha-2,3-sialyltransferase (ST3GAL5) OT27CCUF SIAT9_HUMAN Decreases Expression [28]
Mitochondrial fission 1 protein (FIS1) OT2HL10J FIS1_HUMAN Increases Expression [17]
Angiopoietin-related protein 3 (ANGPTL3) OTCD5Z9W ANGL3_HUMAN Decreases Expression [27]
Eukaryotic translation initiation factor 5A-1 (EIF5A) OTQ8DJX5 IF5A1_HUMAN Affects Response To Substance [54]
------------------------------------------------------------------------------------
⏷ Show the Full List of 1041 DOT(s)
Indication(s) of Lenvatinib
Disease Entry ICD 11 Status REF
Thyroid cancer 2D10 Approved [2]
Thyroid gland follicular carcinoma N.A. Approved [3]
Thyroid gland papillary carcinoma N.A. Approved [3]
Hepatocellular carcinoma 2C12.02 Phase 3 [4]
Renal cell carcinoma 2C90 Phase 3 [5]
Melanoma 2C30 Phase 2 [4]
Solid tumour/cancer 2A00-2F9Z Phase 1/2 [5]
Ovarian cancer 2C73 Phase 1 [6]
Non-small-cell lung cancer 2C25.Y Application submitted [5]
Lenvatinib Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Vascular endothelial growth factor receptor 2 (KDR) TTUTJGQ VGFR2_HUMAN Inhibitor [6]
------------------------------------------------------------------------------------
Lenvatinib Interacts with 1 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [55]
------------------------------------------------------------------------------------

References

1 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
2 FDA Approved Drug Products from FDA Official Website. 2018. Application Number: (ANDA) 208627.
3 Lenvatinib FDA Label
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6 Emerging drugs for ovarian cancer. Expert Opin Emerg Drugs. 2008 Sep;13(3):523-36.
7 The genome-wide expression profile of Scrophularia ningpoensis-treated thapsigargin-stimulated U-87MG cells. Neurotoxicology. 2009 May;30(3):368-76.
8 Endoplasmic reticulum stress impairs insulin signaling through mitochondrial damage in SH-SY5Y cells. Neurosignals. 2012;20(4):265-80.
9 Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides. J Biol Chem. 2018 Apr 13;293(15):5600-5612.
10 Proteomic signatures in thapsigargin-treated hepatoma cells. Chem Res Toxicol. 2011 Aug 15;24(8):1215-22. doi: 10.1021/tx200109y. Epub 2011 Jul 1.
11 Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress. Invest Ophthalmol Vis Sci. 2002 Aug;43(8):2791-8.
12 Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis. Oncogene. 2010 Mar 4;29(9):1329-38. doi: 10.1038/onc.2009.425. Epub 2009 Nov 30.
13 Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J Biol Chem. 2004 Nov 19;279(47):49420-9. doi: 10.1074/jbc.M407700200. Epub 2004 Aug 31.
14 Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase. Bioorg Med Chem. 2010 Aug 1;18(15):5634-46.
15 Tissue transglutaminase serves as an inhibitor of apoptosis by cross-linking caspase 3 in thapsigargin-treated cells. Mol Cell Biol. 2006 Jan;26(2):569-79.
16 Cadmium induces transcription independently of intracellular calcium mobilization. PLoS One. 2011;6(6):e20542.
17 Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress. Br J Pharmacol. 2017 Dec;174(23):4409-4429. doi: 10.1111/bph.14045. Epub 2017 Nov 7.
18 Riluzole induces AR degradation via endoplasmic reticulum stress pathway in androgen-dependent and castration-resistant prostate cancer cells. Prostate. 2019 Feb;79(2):140-150. doi: 10.1002/pros.23719. Epub 2018 Oct 2.
19 Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells. J Biol Chem. 2010 Feb 26;285(9):6091-100. doi: 10.1074/jbc.M109.014092. Epub 2009 Dec 18.
20 Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments. Exp Cell Res. 2009 Apr 1;315(6):968-80. doi: 10.1016/j.yexcr.2009.01.012. Epub 2009 Feb 10.
21 Arsenic trioxide initiates ER stress responses, perturbs calcium signalling and promotes apoptosis in human lens epithelial cells. Exp Eye Res. 2007 Dec;85(6):825-35. doi: 10.1016/j.exer.2007.08.018. Epub 2007 Aug 29.
22 Suppression of the pregnane X receptor during endoplasmic reticulum stress is achieved by down-regulating hepatocyte nuclear factor-4 and up-regulating liver-enriched inhibitory protein. Toxicol Sci. 2015 Apr;144(2):382-92. doi: 10.1093/toxsci/kfv008. Epub 2015 Jan 22.
23 Protective effect against Parkinson's disease-related insults through the activation of XBP1. Brain Res. 2009 Feb 27;1257:16-24. doi: 10.1016/j.brainres.2008.11.104. Epub 2008 Dec 16.
24 DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells. Toxicol Lett. 2014 Jan 30;224(3):395-406. doi: 10.1016/j.toxlet.2013.11.005. Epub 2013 Nov 15.
25 Role of endoplasmic reticulum stress in acrolein-induced endothelial activation. Toxicol Appl Pharmacol. 2009 Jan 1;234(1):14-24. doi: 10.1016/j.taap.2008.09.019. Epub 2008 Oct 7.
26 Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells. Arch Toxicol. 2019 Apr;93(4):965-986. doi: 10.1007/s00204-019-02415-8. Epub 2019 Feb 22.
27 Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity. Cell Biol Toxicol. 2021 Apr;37(2):151-175. doi: 10.1007/s10565-020-09537-1. Epub 2020 Jun 14.
28 Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells. Arch Toxicol. 2021 May;95(5):1631-1645. doi: 10.1007/s00204-021-03014-2. Epub 2021 Mar 26.
29 The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro. Alcohol Clin Exp Res. 2014 Mar;38(3):683-93. doi: 10.1111/acer.12311. Epub 2013 Nov 13.
30 Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer. J Biol Chem. 2022 Feb;298(2):101492. doi: 10.1016/j.jbc.2021.101492. Epub 2021 Dec 13.
31 Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components. J Pharmacol Exp Ther. 2001 Jun;297(3):1025-35.
32 hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress. Biochem J. 2013 Jan 15;449(2):543-53. doi: 10.1042/BJ20120906.
33 Rosiglitazone induces the unfolded protein response, but has no significant effect on cell viability, in monocytic and vascular smooth muscle cells. Biochem Biophys Res Commun. 2010 Oct 1;400(4):689-95. doi: 10.1016/j.bbrc.2010.08.129. Epub 2010 Sep 9.
34 Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. J Pharmacol Exp Ther. 2007 Jun;321(3):830-8. doi: 10.1124/jpet.107.119412. Epub 2007 Mar 1.
35 Doxorubicin prevents endoplasmic reticulum stress-induced apoptosis. Biochem Biophys Res Commun. 2006 Jan 13;339(2):463-8. doi: 10.1016/j.bbrc.2005.11.040. Epub 2005 Nov 15.
36 Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57. Br J Cancer. 2007 Apr 10;96(7):1062-71. doi: 10.1038/sj.bjc.6603672. Epub 2007 Mar 13.
37 Role of calcium in lipopolysaccharide-induced calcitonin gene expression in human adipocytes. Innate Immun. 2011 Aug;17(4):403-13. doi: 10.1177/1753425910377100. Epub 2010 Aug 3.
38 Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells. Cancer Res. 2007 Feb 1;67(3):1262-9. doi: 10.1158/0008-5472.CAN-06-1794.
39 BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells. Br J Cancer. 2006 Feb 13;94(3):407-26. doi: 10.1038/sj.bjc.6602935.
40 Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep;36(3):592-601. doi: 10.1053/jhep.2002.35441.
41 Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signaling. Neuropharmacology. 2006 Apr;50(5):558-67. doi: 10.1016/j.neuropharm.2005.10.016. Epub 2006 Jan 4.
42 Heat shock induces preferential translation of ERGIC-53 and affects its recycling pathway. J Biol Chem. 2004 Oct 8;279(41):42535-44. doi: 10.1074/jbc.M401860200. Epub 2004 Jul 29.
43 Inhibin beta E is upregulated by drug-induced endoplasmic reticulum stress as a transcriptional target gene of ATF4. Toxicol Appl Pharmacol. 2012 Oct 15;264(2):300-4. doi: 10.1016/j.taap.2012.08.011. Epub 2012 Aug 23.
44 Regulation of antiprotease and antimicrobial protein secretion by airway submucosal gland serous cells. J Biol Chem. 2004 Sep 10;279(37):38854-60. doi: 10.1074/jbc.M407077200. Epub 2004 Jul 2.
45 Lipocalin 2, a new GADD153 target gene, as an apoptosis inducer of endoplasmic reticulum stress in lung cancer cells. Toxicol Appl Pharmacol. 2012 Sep 15;263(3):330-7. doi: 10.1016/j.taap.2012.07.005. Epub 2012 Jul 16.
46 Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation. J Membr Biol. 2010 Feb;233(1-3):105-18. doi: 10.1007/s00232-010-9230-0. Epub 2010 Feb 4.
47 Translational repression of MCL-1 couples stress-induced eIF2 alpha phosphorylation to mitochondrial apoptosis initiation. J Biol Chem. 2007 Aug 3;282(31):22551-62. doi: 10.1074/jbc.M702673200. Epub 2007 Jun 6.
48 Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours. Apoptosis. 2007 Mar;12(3):613-22. doi: 10.1007/s10495-006-0020-1.
49 High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities. Arch Toxicol. 2017 Mar;91(3):1367-1383. doi: 10.1007/s00204-016-1781-0. Epub 2016 Jun 29.
50 Transcriptional regulation of VEGFA by the endoplasmic reticulum stress transducer OASIS in ARPE-19 cells. PLoS One. 2013;8(1):e55155. doi: 10.1371/journal.pone.0055155. Epub 2013 Jan 30.
51 Inhibition of activity/expression, or genetic deletion, of ERO1 blunts arsenite geno- and cyto-toxicity. Food Chem Toxicol. 2022 Oct;168:113360. doi: 10.1016/j.fct.2022.113360. Epub 2022 Aug 12.
52 Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation. Cell Metab. 2013 Dec 3;18(6):908-19. doi: 10.1016/j.cmet.2013.11.006.
53 Fibroblast growth factor 21 is induced by endoplasmic reticulum stress. Biochimie. 2013 Apr;95(4):692-9. doi: 10.1016/j.biochi.2012.10.019. Epub 2012 Nov 2.
54 eIF5A promotes translation elongation, polysome disassembly and stress granule assembly. PLoS One. 2010 Apr 1;5(4):e9942. doi: 10.1371/journal.pone.0009942.
55 Influence of CYP3A4/5 and ABC transporter polymorphisms on lenvatinib plasma trough concentrations in Japanese patients with thyroid cancer. Sci Rep. 2019 Apr 1;9(1):5404.