Details of the Drug Combination

General Information of Drug Combination (ID: DCL9I1D)

• Drug Combination Name: THAPSIGARGIN + Prazosin
• Indication: Diffuse intrinsic pontine glioma; Status: Investigative [1]
• Component Drugs:
  THAPSIGARGIN (DMDMQIE): Small molecular drug
  Prazosin (DMCD9YG): Small molecular drug
• High-throughput Screening Result:
  Testing Cell Line: SU-DIPG-XIII
  Zero Interaction Potency (ZIP) Score: 0.626
  Bliss Independence Score: 0.244
  Loewe Additivity Score: 1.907
  LHighest Single Agent (HSA) Score: 3.368

Molecular Interaction Atlas of This Drug Combination

THAPSIGARGIN Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Sarcoplasmic/endoplasmic reticulum calcium ATPase (ATP2A)	TTZVSJ2	NOUNIPROTAC	Inhibitor	[11]

THAPSIGARGIN Interacts with 1041 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Baculoviral IAP repeat-containing protein 2 (BIRC2)	OTFXFREP	BIRC2_HUMAN	Decreases Expression	[12]
Serine/threonine-protein kinase PLK4 (PLK4)	OTV8KZDZ	PLK4_HUMAN	Increases Expression	[4]
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CACNA1A)	OTY08SIX	CAC1A_HUMAN	Increases Expression	[4]
Dihydropyrimidinase-related protein 4 (DPYSL4)	OT3SBS2S	DPYL4_HUMAN	Increases Expression	[4]
BET1 homolog (BET1)	OTGX2557	BET1_HUMAN	Decreases Expression	[4]
Intermediate conductance calcium-activated potassium channel protein 4 (KCNN4)	OTQKQ346	KCNN4_HUMAN	Increases Expression	[4]
Leucine-rich repeat transmembrane protein FLRT2 (FLRT2)	OTGD8TID	FLRT2_HUMAN	Decreases Expression	[4]
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44)	OTXP7MXN	TIM44_HUMAN	Decreases Expression	[4]
Golgi SNAP receptor complex member 1 (GOSR1)	OTX8TMVU	GOSR1_HUMAN	Decreases Expression	[4]
Glutathione reductase, mitochondrial (GSR)	OTM2TUYM	GSHR_HUMAN	Decreases Expression	[4]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Decreases Expression	[4]
Plasminogen activator inhibitor 2 (SERPINB2)	OT72QLZB	PAI2_HUMAN	Increases Expression	[4]
Endoplasmin (HSP90B1)	OT02XLBR	ENPL_HUMAN	Decreases Expression	[4]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Increases Expression	[4]
Peroxiredoxin-5, mitochondrial (PRDX5)	OTUEKZ18	PRDX5_HUMAN	Decreases Expression	[4]
Dual specificity protein kinase TTK (TTK)	OTBY1Z5H	TTK_HUMAN	Increases Expression	[4]
DNA replication licensing factor MCM7 (MCM7)	OT6FXC6K	MCM7_HUMAN	Increases Expression	[4]
Centromere protein F (CENPF)	OT7AG0SW	CENPF_HUMAN	Increases Expression	[4]
ETS domain-containing transcription factor ERF (ERF)	OTGTA85X	ERF_HUMAN	Increases Expression	[4]
Hepatoma-derived growth factor (HDGF)	OT16PTBC	HDGF_HUMAN	Increases Expression	[4]
Serine/threonine-protein kinase PLK1 (PLK1)	OTRZX45T	PLK1_HUMAN	Increases Expression	[4]
Protein max (MAX)	OTKZ0YKM	MAX_HUMAN	Decreases Expression	[4]
Cytochrome P450 4F3 (CYP4F3)	OTYNSQAM	CP4F3_HUMAN	Decreases Expression	[4]
Neuroblast differentiation-associated protein AHNAK (AHNAK)	OT6KH1WG	AHNK_HUMAN	Increases Expression	[4]
Cell division cycle protein 20 homolog (CDC20)	OTCOEZRV	CDC20_HUMAN	Increases Expression	[4]
Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5)	OT6T408U	MP2K5_HUMAN	Decreases Expression	[4]
Scavenger receptor class A member 3 (SCARA3)	OT46I38Y	SCAR3_HUMAN	Increases Expression	[4]
Sideroflexin-4 (SFXN4)	OT2KLSS9	SFXN4_HUMAN	Decreases Expression	[4]
V-type proton ATPase subunit d 2 (ATP6V0D2)	OTMOZJO0	VA0D2_HUMAN	Decreases Expression	[4]
Serine/threonine-protein kinase 32A (STK32A)	OTONYLYO	ST32A_HUMAN	Decreases Expression	[4]
Fibroblast growth factor 13 (FGF13)	OTHNNVSG	FGF13_HUMAN	Decreases Expression	[4]
BTB/POZ domain-containing protein KCTD12 (KCTD12)	OTPYKT4Z	KCD12_HUMAN	Increases Expression	[4]
Cation channel sperm-associated protein 2 (CATSPER2)	OT1841AS	CTSR2_HUMAN	Decreases Expression	[4]
Kinesin-like protein KIF20B (KIF20B)	OTS68AHH	KI20B_HUMAN	Increases Expression	[4]
Sodium channel protein type 2 subunit alpha (SCN2A)	OTUSYE4Z	SCN2A_HUMAN	Increases Expression	[4]
Protein S100-A13 (S100A13)	OT582SUS	S10AD_HUMAN	Increases Expression	[4]
Kinesin-like protein KIF2C (KIF2C)	OTJ8G3NP	KIF2C_HUMAN	Increases Expression	[4]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1)	OTJGE772	CHAC1_HUMAN	Decreases Expression	[4]
Kinesin-like protein KIF15 (KIF15)	OTJRJEXL	KIF15_HUMAN	Increases Expression	[4]
DnaJ homolog subfamily B member 11 (DNAJB11)	OTDDK2SY	DJB11_HUMAN	Decreases Expression	[4]
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1)	OTVIHD77	MACF1_HUMAN	Increases Expression	[4]
C-type lectin domain family 11 member A (CLEC11A)	OT9KBH7C	CLC11_HUMAN	Increases Expression	[4]
Period circadian protein homolog 1 (PER1)	OTVQF3WX	PER1_HUMAN	Increases Expression	[13]
Protein c-Fos (FOS)	OTJBUVWS	FOS_HUMAN	Increases Expression	[13]
Glycoprotein hormones alpha chain (CGA)	OT00U3Y3	GLHA_HUMAN	Increases Expression	[13]
Metallothionein-1A (MT1A)	OTKBH52X	MT1A_HUMAN	Increases Expression	[13]
Inhibin beta A chain (INHBA)	OTSP64PQ	INHBA_HUMAN	Increases Expression	[13]
Prostaglandin G/H synthase 2 (PTGS2)	OT75U9M4	PGH2_HUMAN	Increases Expression	[13]
Nuclear receptor subfamily 4 group A member 2 (NR4A2)	OT3F9IR2	NR4A2_HUMAN	Increases Expression	[13]
Protein FosB (FOSB)	OTW6C05J	FOSB_HUMAN	Increases Expression	[13]
GTP-binding protein GEM (GEM)	OT6SK8ZV	GEM_HUMAN	Increases Expression	[13]
PLAC8-like protein 1 (PLAC8L1)	OTHF4LKX	PL8L1_HUMAN	Increases Expression	[5]
Protein tyrosine phosphatase domain-containing protein 1 (PTPDC1)	OTTM4N1J	PTPC1_HUMAN	Increases Expression	[5]
Mapk-regulated corepressor-interacting protein 1 (MCRIP1)	OTY3EW73	MCRI1_HUMAN	Decreases Expression	[5]
Deoxyribonuclease-2-alpha (DNASE2)	OT6RC1BL	DNS2A_HUMAN	Increases Expression	[5]
Serine/threonine-protein kinase Sgk1 (SGK1)	OT301T1U	SGK1_HUMAN	Decreases Expression	[5]
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7)	OT7C68YV	BACH_HUMAN	Decreases Expression	[5]
HCLS1-associated protein X-1 (HAX1)	OTOJWV3F	HAX1_HUMAN	Increases Expression	[5]
Potassium channel subfamily K member 1 (KCNK1)	OTBXPTKX	KCNK1_HUMAN	Decreases Expression	[5]
Cell division cycle 7-related protein kinase (CDC7)	OT5133XY	CDC7_HUMAN	Decreases Expression	[5]
Pyruvate dehydrogenase protein X component, mitochondrial (PDHX)	OTG7O271	ODPX_HUMAN	Decreases Expression	[5]
Homeobox protein Meis1 (MEIS1)	OTH9DKAD	MEIS1_HUMAN	Decreases Expression	[5]
Cytochrome c oxidase subunit NDUFA4 (NDUFA4)	OTDVH3QG	NDUA4_HUMAN	Decreases Expression	[5]
Membrane-associated phosphatidylinositol transfer protein 1 (PITPNM1)	OTIUYAG5	PITM1_HUMAN	Increases Expression	[5]
Nucleoside diphosphate kinase, mitochondrial (NME4)	OT2JTT42	NDKM_HUMAN	Decreases Expression	[5]
Class E basic helix-loop-helix protein 40 (BHLHE40)	OTITX14U	BHE40_HUMAN	Decreases Expression	[5]
Acyl carrier protein, mitochondrial (NDUFAB1)	OTF906UR	ACPM_HUMAN	Decreases Expression	[5]
Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1)	OTFX1KCG	DC1I1_HUMAN	Decreases Expression	[5]
Ectoderm-neural cortex protein 1 (ENC1)	OTJEUB6U	ENC1_HUMAN	Decreases Expression	[5]
Serine/threonine-protein kinase Chk1 (CHEK1)	OTTTI622	CHK1_HUMAN	Decreases Expression	[5]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)	OTA1CPBV	TR10B_HUMAN	Increases Expression	[5]
Serine/threonine-protein phosphatase with EF-hands 1 (PPEF1)	OT3X4HCS	PPE1_HUMAN	Decreases Expression	[5]
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK)	OTDLYLRZ	BCKD_HUMAN	Decreases Expression	[5]
Tax1-binding protein 3 (TAX1BP3)	OTQ6IB4T	TX1B3_HUMAN	Decreases Expression	[5]
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23)	OTAAS85T	TIM23_HUMAN	Decreases Expression	[5]
Phosphoribosylformylglycinamidine synthase (PFAS)	OTCOBYYK	PUR4_HUMAN	Decreases Expression	[5]
Mitochondrial ribonuclease P catalytic subunit (PRORP)	OTWIS44P	MRPP3_HUMAN	Decreases Expression	[5]
Actin-related protein 2/3 complex subunit 3 (ARPC3)	OTKWVF8P	ARPC3_HUMAN	Increases Expression	[5]
Surfeit locus protein 4 (SURF4)	OTCSXJ9C	SURF4_HUMAN	Increases Expression	[5]
Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2)	OT8L6EGI	BCAT2_HUMAN	Increases Expression	[5]
Insulin-induced gene 1 protein (INSIG1)	OTZF5X1D	INSI1_HUMAN	Decreases Expression	[5]
Regulator of G-protein signaling 5 (RGS5)	OTUY0Q2I	RGS5_HUMAN	Decreases Expression	[5]
Cytochrome b5 type B (CYB5B)	OTONNAV1	CYB5B_HUMAN	Decreases Expression	[5]
D-3-phosphoglycerate dehydrogenase (PHGDH)	OT1LMRTG	SERA_HUMAN	Increases Expression	[5]
Mitogen-activated protein kinase kinase kinase 13 (MAP3K13)	OTS93BTX	M3K13_HUMAN	Decreases Expression	[5]
Protein Mis18-beta (OIP5)	OTI5C2DE	MS18B_HUMAN	Decreases Expression	[5]
Protein sprouty homolog 2 (SPRY2)	OTH0CRCZ	SPY2_HUMAN	Decreases Expression	[5]
Protein regulator of cytokinesis 1 (PRC1)	OTHD0XS0	PRC1_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3)	OTDV12IF	NDUB3_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 subunit C1, mitochondrial (NDUFC1)	OTJ5TNHB	NDUC1_HUMAN	Decreases Expression	[5]
Lipoyl synthase, mitochondrial (LIAS)	OTOSW67J	LIAS_HUMAN	Increases Expression	[5]
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20)	OT6CLFXB	MCAT_HUMAN	Increases Expression	[5]
Asparagine--tRNA ligase, cytoplasmic (NARS1)	OTFS4J1W	SYNC_HUMAN	Increases Expression	[5]
NADH dehydrogenase iron-sulfur protein 5 (NDUFS5)	OTF40UYJ	NDUS5_HUMAN	Decreases Expression	[5]
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A)	OTDX9687	TIM8A_HUMAN	Decreases Expression	[5]
tRNA wybutosine-synthesizing protein 4 (LCMT2)	OT4RUVCM	TYW4_HUMAN	Decreases Expression	[5]
BMP/retinoic acid-inducible neural-specific protein 1 (BRINP1)	OTEUVSCP	BRNP1_HUMAN	Decreases Expression	[5]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B)	OT8KME51	BUB1B_HUMAN	Decreases Expression	[5]
Receptor activity-modifying protein 1 (RAMP1)	OT7UT2XB	RAMP1_HUMAN	Decreases Expression	[5]
Frizzled-7 (FZD7)	OTTK3F6E	FZD7_HUMAN	Decreases Expression	[5]
Low-density lipoprotein receptor-related protein 4 (LRP4)	OTO4M459	LRP4_HUMAN	Decreases Expression	[5]
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4)	OT4CA13K	ATS4_HUMAN	Decreases Expression	[5]
Liprin-alpha-4 (PPFIA4)	OTWXG0DO	LIPA4_HUMAN	Decreases Expression	[5]
Adapter SH3BGRL (SH3BGRL)	OTUOCTMT	SH3L1_HUMAN	Decreases Expression	[5]
DNA polymerase theta (POLQ)	OTBHK0E6	DPOLQ_HUMAN	Decreases Expression	[5]
Cell division control protein 45 homolog (CDC45)	OT6NNLOD	CDC45_HUMAN	Decreases Expression	[5]
Geminin (GMNN)	OTDYKNIY	GEMI_HUMAN	Decreases Expression	[5]
Barrier-to-autointegration factor (BANF1)	OTP7Z38L	BAF_HUMAN	Decreases Expression	[5]
Peptide chain release factor 1, mitochondrial (MTRF1)	OTRTUUM4	RF1M_HUMAN	Increases Expression	[5]
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT)	OT6WZPWV	KBL_HUMAN	Decreases Expression	[5]
Ribonuclease H2 subunit A (RNASEH2A)	OT8G3G7K	RNH2A_HUMAN	Decreases Expression	[5]
Ribonuclease P protein subunit p20 (POP7)	OTKC7SG5	POP7_HUMAN	Decreases Expression	[5]
Protein SCO1 homolog, mitochondrial (SCO1)	OTC45UGB	SCO1_HUMAN	Decreases Expression	[5]
Short-chain dehydrogenase/reductase 3 (DHRS3)	OTSK1DTP	DHRS3_HUMAN	Increases Expression	[5]
Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2)	OTR99SJ8	CDKA2_HUMAN	Increases Expression	[5]
Stanniocalcin-2 (STC2)	OT86YP8G	STC2_HUMAN	Increases Expression	[5]
Bestrophin-1 (BEST1)	OTWHE1ZC	BEST1_HUMAN	Increases Expression	[5]
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH1)	OT1U2GWG	DDAH1_HUMAN	Decreases Expression	[5]
Regulator of G-protein signaling 11 (RGS11)	OTIAZ36F	RGS11_HUMAN	Increases Expression	[5]
Slit homolog 2 protein (SLIT2)	OTLS2RJ4	SLIT2_HUMAN	Decreases Expression	[5]
Dickkopf-related protein 1 (DKK1)	OTRDLUSP	DKK1_HUMAN	Decreases Expression	[5]
Glutaminase kidney isoform, mitochondrial (GLS)	OTGOZG2M	GLSK_HUMAN	Increases Expression	[5]
Protein transport protein Sec31A (SEC31A)	OT2U42AC	SC31A_HUMAN	Increases Expression	[5]
Meiotic recombination protein REC8 homolog (REC8)	OT6JAVXE	REC8_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6)	OTIXNT91	NDUB6_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3)	OTXL10N9	NDUA3_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial (NDUFB8)	OTW4A4Q0	NDUB8_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 alpha subcomplex subunit 7 (NDUFA7)	OT8CV3H5	NDUA7_HUMAN	Decreases Expression	[5]
Chondroitin sulfate proteoglycan 5 (CSPG5)	OTXFEBWR	CSPG5_HUMAN	Decreases Expression	[5]
Mitochondrial proton/calcium exchanger protein (LETM1)	OT8N4MRU	LETM1_HUMAN	Decreases Expression	[5]
Kinesin-like protein KIF20A (KIF20A)	OTXOQHE0	KI20A_HUMAN	Decreases Expression	[5]
Chromosome-associated kinesin KIF4A (KIF4A)	OT3UWL7D	KIF4A_HUMAN	Decreases Expression	[5]
Phosphoacetylglucosamine mutase (PGM3)	OTHS1ZSP	AGM1_HUMAN	Increases Expression	[5]
Echinoderm microtubule-associated protein-like 2 (EML2)	OTRX2NTA	EMAL2_HUMAN	Increases Expression	[5]
Securin (PTTG1)	OTIMYS4W	PTTG1_HUMAN	Decreases Expression	[5]
Cytochrome b (CYTB)	OTAHB98A	CYB_HUMAN	Decreases Expression	[5]
Cytochrome b5 (CYB5A)	OT6SN4RM	CYB5_HUMAN	Decreases Expression	[5]
Cytochrome c oxidase subunit 1 (COX1)	OTG3O9BN	COX1_HUMAN	Decreases Expression	[5]
Cytochrome c oxidase subunit 2 (COX2)	OTTMVBJJ	COX2_HUMAN	Decreases Expression	[5]
Cytochrome c oxidase subunit 3 (COX3)	OTNNGBYJ	COX3_HUMAN	Decreases Expression	[5]
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1)	OTOEEEXG	HPRT_HUMAN	Decreases Expression	[5]
Aspartate aminotransferase, mitochondrial (GOT2)	OT6XBWN0	AATM_HUMAN	Decreases Expression	[5]
Phosphoglycerate kinase 1 (PGK1)	OT6V1ICH	PGK1_HUMAN	Decreases Expression	[5]
ATP synthase subunit a (ATP6)	OTPHOGLX	ATP6_HUMAN	Decreases Expression	[5]
Complement C5 (C5)	OTSL3OIC	CO5_HUMAN	Increases Expression	[5]
Low-density lipoprotein receptor (LDLR)	OTH559LU	LDLR_HUMAN	Decreases Expression	[5]
NADH-ubiquinone oxidoreductase chain 1 (ND1)	OTCLGIXV	NU1M_HUMAN	Decreases Expression	[5]
NADH-ubiquinone oxidoreductase chain 2 (ND2)	OTG9OHOX	NU2M_HUMAN	Decreases Expression	[5]
NADH-ubiquinone oxidoreductase chain 3 (ND3)	OT1OC3K3	NU3M_HUMAN	Decreases Expression	[5]
NADH-ubiquinone oxidoreductase chain 4L (ND4L)	OTTMZA4Q	NU4LM_HUMAN	Decreases Expression	[5]
NADH-ubiquinone oxidoreductase chain 4 (ND4)	OT4RQVAA	NU4M_HUMAN	Decreases Expression	[5]
NADH-ubiquinone oxidoreductase chain 5 (ND5)	OT45LW1K	NU5M_HUMAN	Decreases Expression	[5]
NADH-ubiquinone oxidoreductase chain 6 (ND6)	OTG47B7B	NU6M_HUMAN	Decreases Expression	[5]
ATP synthase protein 8 (ATP8)	OTYQQR53	ATP8_HUMAN	Decreases Expression	[5]
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR)	OTRT3F3U	HMDH_HUMAN	Decreases Expression	[5]
RAF proto-oncogene serine/threonine-protein kinase (RAF1)	OT51LSFO	RAF1_HUMAN	Decreases Expression	[5]
Superoxide dismutase , mitochondrial (SOD2)	OTIWXGZ9	SODM_HUMAN	Decreases Expression	[5]
Ornithine aminotransferase, mitochondrial (OAT)	OTEKO8CT	OAT_HUMAN	Decreases Expression	[5]
Thymidine kinase, cytosolic (TK1)	OTY5JFM1	KITH_HUMAN	Decreases Expression	[5]
N-myc proto-oncogene protein (MYCN)	OTWD33K1	MYCN_HUMAN	Decreases Expression	[5]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1)	OTEG4KU9	RPN1_HUMAN	Increases Expression	[5]
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB)	OTXUN47K	PCCB_HUMAN	Decreases Expression	[5]
ATP synthase F(0) complex subunit C1, mitochondrial (ATP5MC1)	OTOLSYOI	AT5G1_HUMAN	Decreases Expression	[5]
Cyclin-dependent kinase 1 (CDK1)	OTW1SC2N	CDK1_HUMAN	Decreases Expression	[5]
Glia-derived nexin (SERPINE2)	OTYF5340	GDN_HUMAN	Increases Expression	[5]
Acyl-CoA-binding protein (DBI)	OT884QY9	ACBP_HUMAN	Decreases Expression	[5]
Vitamin K-dependent protein S (PROS1)	OTXQWNOI	PROS_HUMAN	Decreases Expression	[5]
Protein disulfide-isomerase (P4HB)	OTTYNYPF	PDIA1_HUMAN	Increases Expression	[5]
Bifunctional glutamate/proline--tRNA ligase (EPRS1)	OTXK0FLB	SYEP_HUMAN	Increases Expression	[5]
Heat shock protein HSP 90-alpha (HSP90AA1)	OTLG1WPK	HS90A_HUMAN	Decreases Expression	[5]
Laminin subunit beta-1 (LAMB1)	OT6J9LJR	LAMB1_HUMAN	Increases Expression	[5]
Proto-oncogene tyrosine-protein kinase receptor Ret (RET)	OTLU040A	RET_HUMAN	Decreases Expression	[5]
Fumarate hydratase, mitochondrial (FH)	OTEQWU6Q	FUMH_HUMAN	Decreases Expression	[5]
Amino acid transporter heavy chain SLC3A2 (SLC3A2)	OTBR33M9	4F2_HUMAN	Increases Expression	[5]
Signal recognition particle receptor subunit alpha (SRPRA)	OT5NMYTY	SRPRA_HUMAN	Increases Expression	[5]
Asparagine synthetase (ASNS)	OT8R922G	ASNS_HUMAN	Increases Expression	[5]
Annexin A5 (ANXA5)	OTZS877V	ANXA5_HUMAN	Increases Expression	[5]
Neuromedin-B (NMB)	OT4NLN6H	NMB_HUMAN	Decreases Expression	[5]
Hemoglobin subunit theta-1 (HBQ1)	OTU12ZTW	HBAT_HUMAN	Decreases Expression	[5]
Galectin-1 (LGALS1)	OT8LDFWR	LEG1_HUMAN	Decreases Expression	[5]
Fructose-1,6-bisphosphatase 1 (FBP1)	OTQBANEP	F16P1_HUMAN	Decreases Expression	[5]
Dihydrolipoyl dehydrogenase, mitochondrial (DLD)	OT378CU9	DLDH_HUMAN	Decreases Expression	[5]
Cytochrome c oxidase subunit 6C (COX6C)	OT3V7JE5	COX6C_HUMAN	Decreases Expression	[5]
Fructose-bisphosphate aldolase C (ALDOC)	OTEC13I5	ALDOC_HUMAN	Decreases Expression	[5]
Thymosin beta-15A (TMSB15A)	OTSBWCES	TB15A_HUMAN	Decreases Expression	[5]
Heat shock 70 kDa protein 1A (HSPA1A)	OTKGIE76	HS71A_HUMAN	Decreases Expression	[5]
Alpha-amylase 1B (AMY1A)	OT6G4B8O	AMY1B_HUMAN	Decreases Expression	[5]
Transcriptional activator Myb (MYB)	OTJH64IV	MYB_HUMAN	Decreases Expression	[5]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Increases Expression	[5]
Chromogranin-A (CHGA)	OTXYX5JH	CMGA_HUMAN	Decreases Expression	[5]
Mast/stem cell growth factor receptor Kit (KIT)	OTHUY3VZ	KIT_HUMAN	Increases Expression	[5]
60 kDa heat shock protein, mitochondrial (HSPD1)	OTTO1Y11	CH60_HUMAN	Decreases Expression	[5]
Heat shock cognate 71 kDa protein (HSPA8)	OTJI2RCI	HSP7C_HUMAN	Decreases Expression	[5]
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB)	OT2NHE5E	ODPB_HUMAN	Decreases Expression	[5]
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1)	OTMKHVWC	C1TC_HUMAN	Decreases Expression	[5]
Proliferating cell nuclear antigen (PCNA)	OTHZ1RIA	PCNA_HUMAN	Decreases Expression	[5]
Neurofilament heavy polypeptide (NEFH)	OTMSCW5I	NFH_HUMAN	Decreases Expression	[5]
ADP/ATP translocase 1 (SLC25A4)	OTKYLK2J	ADT1_HUMAN	Decreases Expression	[5]
Creatine kinase B-type (CKB)	OTUCKOTT	KCRB_HUMAN	Decreases Expression	[5]
Alpha-actinin-1 (ACTN1)	OTUCLNXH	ACTN1_HUMAN	Decreases Expression	[5]
Secretogranin-2 (SCG2)	OTUHXX8U	SCG2_HUMAN	Increases Expression	[5]
Protein disulfide-isomerase A4 (PDIA4)	OTVFUJ13	PDIA4_HUMAN	Increases Expression	[5]
Plastin-3 (PLS3)	OTYBM4PK	PLST_HUMAN	Increases Expression	[5]
Beta-enolase (ENO3)	OT3HYKYI	ENOB_HUMAN	Increases Expression	[5]
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2)	OT1LQSGX	MTDC_HUMAN	Increases Expression	[5]
Pyruvate kinase PKM (PKM)	OTLHHMC2	KPYM_HUMAN	Decreases Expression	[5]
G2/mitotic-specific cyclin-B1 (CCNB1)	OT19S7E5	CCNB1_HUMAN	Decreases Expression	[5]
Cytochrome c oxidase subunit 6B1 (COX6B1)	OTNKXYQI	CX6B1_HUMAN	Decreases Expression	[5]
Platelet-derived growth factor receptor alpha (PDGFRA)	OTDJXUCN	PGFRA_HUMAN	Decreases Expression	[5]
Histone H1.2 (H1-2)	OT0AVI4M	H12_HUMAN	Increases Expression	[5]
Stathmin (STMN1)	OTDJ4RV0	STMN1_HUMAN	Decreases Expression	[5]
Protein kinase C alpha type (PRKCA)	OT5UWNRD	KPCA_HUMAN	Decreases Expression	[5]
CCAAT/enhancer-binding protein beta (CEBPB)	OTM9MQIA	CEBPB_HUMAN	Increases Expression	[5]
Neuromodulin (GAP43)	OT2OTGGV	NEUM_HUMAN	Decreases Expression	[5]
CTP synthase 1 (CTPS1)	OTZ9J6ZG	PYRG1_HUMAN	Decreases Expression	[5]
Insulin-like growth factor-binding protein 3 (IGFBP3)	OTIX63TX	IBP3_HUMAN	Increases Expression	[5]
Insulin-like growth factor-binding protein 2 (IGFBP2)	OTG1P60E	IBP2_HUMAN	Decreases Expression	[5]
ADP-ribosylation factor 4 (ARF4)	OT3GMDHA	ARF4_HUMAN	Increases Expression	[5]
Early growth response protein 1 (EGR1)	OTCP6XGZ	EGR1_HUMAN	Decreases Expression	[5]
Phosphoglycerate mutase 1 (PGAM1)	OTZ5DB06	PGAM1_HUMAN	Decreases Expression	[5]
NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2)	OTSZF7D6	NDUV2_HUMAN	Decreases Expression	[5]
Casein kinase II subunit alpha' (CSNK2A2)	OT7MA2LV	CSK22_HUMAN	Increases Expression	[5]
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2)	OTXF0B09	IF2B_HUMAN	Increases Expression	[5]
Cyclin-A2 (CCNA2)	OTPHHYZJ	CCNA2_HUMAN	Decreases Expression	[5]
Aromatic-L-amino-acid decarboxylase (DDC)	OT0TSW09	DDC_HUMAN	Decreases Expression	[5]
Amine oxidase A (MAOA)	OT8NIWMQ	AOFA_HUMAN	Decreases Expression	[5]
Diamine acetyltransferase 1 (SAT1)	OT52AU22	SAT1_HUMAN	Increases Expression	[5]
Oxysterol-binding protein 1 (OSBP)	OT7R0OQQ	OSBP1_HUMAN	Increases Expression	[5]
Galanin peptides (GAL)	OTB3VPTO	GALA_HUMAN	Decreases Expression	[5]
NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)	OTPDCK1F	ADRO_HUMAN	Increases Expression	[5]
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)	OTBZKX4P	ROA2_HUMAN	Decreases Expression	[5]
Splicing factor, proline- and glutamine-rich (SFPQ)	OTLCIAPJ	SFPQ_HUMAN	Decreases Expression	[5]
Peptidyl-prolyl cis-trans isomerase B (PPIB)	OTLPH6KN	PPIB_HUMAN	Increases Expression	[5]
Glycine dehydrogenase (GLDC)	OTVVDNW0	GCSP_HUMAN	Decreases Expression	[5]
Tumor necrosis factor ligand superfamily member 4 (TNFSF4)	OTOCBX7P	TNFL4_HUMAN	Increases Expression	[5]
Endothelial transcription factor GATA-2 (GATA2)	OTBP2QQ2	GATA2_HUMAN	Decreases Expression	[5]
Ribonucleoside-diphosphate reductase large subunit (RRM1)	OTXGQOR9	RIR1_HUMAN	Decreases Expression	[5]
Cytochrome c oxidase subunit 7B, mitochondrial (COX7B)	OT67PIDP	COX7B_HUMAN	Decreases Expression	[5]
Protein kinase C eta type (PRKCH)	OTC498N5	KPCL_HUMAN	Decreases Expression	[5]
Tenascin (TNC)	OTK4FSHR	TENA_HUMAN	Decreases Expression	[5]
Cyclin-dependent kinase 2 (CDK2)	OTB5DYYZ	CDK2_HUMAN	Decreases Expression	[5]
DNA replication licensing factor MCM3 (MCM3)	OTOOHQPM	MCM3_HUMAN	Decreases Expression	[5]
Laminin subunit alpha-1 (LAMA1)	OTQZMP86	LAMA1_HUMAN	Decreases Expression	[5]
ATP synthase subunit alpha, mitochondrial (ATP5F1A)	OT3FZDLX	ATPA_HUMAN	Increases Expression	[5]
Proteasome subunit alpha type-2 (PSMA2)	OTJRT2ZL	PSA2_HUMAN	Decreases Expression	[5]
Protein S100-A4 (S100A4)	OTLRGFSQ	S10A4_HUMAN	Decreases Expression	[5]
Threonine--tRNA ligase 1, cytoplasmic (TARS1)	OT0PWST5	SYTC_HUMAN	Increases Expression	[5]
Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2)	OTHBZHX0	FKBP2_HUMAN	Increases Expression	[5]
Hepatocyte growth factor-like protein (MST1)	OTOC4UNG	HGFL_HUMAN	Increases Expression	[5]
Adenylate kinase 4, mitochondrial (AK4)	OTA0T02Q	KAD4_HUMAN	Decreases Expression	[5]
Calreticulin (CALR)	OTYD2TR1	CALR_HUMAN	Increases Expression	[5]
Calnexin (CANX)	OTYP1F6J	CALX_HUMAN	Increases Expression	[5]
Cellular retinoic acid-binding protein 2 (CRABP2)	OTY01V9G	RABP2_HUMAN	Decreases Expression	[5]
Cellular retinoic acid-binding protein 1 (CRABP1)	OTISDG5X	RABP1_HUMAN	Decreases Expression	[5]
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3)	OTLB2WEU	PRDX3_HUMAN	Decreases Expression	[5]
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A)	OTYA3GB4	2AAA_HUMAN	Decreases Expression	[5]
Neuronal acetylcholine receptor subunit alpha-5 (CHRNA5)	OTGIL2YD	ACHA5_HUMAN	Decreases Expression	[5]
Translocator protein (TSPO)	OTSU7ESK	TSPO_HUMAN	Decreases Expression	[5]
High affinity cationic amino acid transporter 1 (SLC7A1)	OTR2ZVA8	CTR1_HUMAN	Increases Expression	[5]
Neuronal acetylcholine receptor subunit beta-4 (CHRNB4)	OTIV4MC1	ACHB4_HUMAN	Decreases Expression	[5]
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA)	OTOJ8QFF	SDHA_HUMAN	Decreases Expression	[5]
Coronin-1A (CORO1A)	OTVAZOHC	COR1A_HUMAN	Decreases Expression	[5]
Ribonucleoside-diphosphate reductase subunit M2 (RRM2)	OTOB6J6R	RIR2_HUMAN	Decreases Expression	[5]
DnaJ homolog subfamily A member 1 (DNAJA1)	OT38BZQQ	DNJA1_HUMAN	Decreases Expression	[5]
RAC-alpha serine/threonine-protein kinase (AKT1)	OT8H2YY7	AKT1_HUMAN	Decreases Phosphorylation	[5]
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)	OTCMMMIZ	3HIDH_HUMAN	Decreases Expression	[5]
Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3)	OTCZQY1U	ACHA3_HUMAN	Decreases Expression	[5]
Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1)	OTQHB52T	P5CR1_HUMAN	Increases Expression	[5]
Cleavage stimulation factor subunit 2 (CSTF2)	OTR6G4II	CSTF2_HUMAN	Decreases Expression	[5]
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT)	OT0THBVA	DUT_HUMAN	Decreases Expression	[5]
ER lumen protein-retaining receptor 2 (KDELR2)	OT9QW7Q0	ERD22_HUMAN	Increases Expression	[5]
DNA replication licensing factor MCM4 (MCM4)	OT19PNNG	MCM4_HUMAN	Decreases Expression	[5]
DNA replication licensing factor MCM5 (MCM5)	OTAHLB62	MCM5_HUMAN	Decreases Expression	[5]
Serine hydroxymethyltransferase, mitochondrial (SHMT2)	OT5NCAZN	GLYM_HUMAN	Increases Expression	[5]
Heat shock 70 kDa protein 1-like (HSPA1L)	OTC2V1K6	HS71L_HUMAN	Decreases Expression	[5]
Prohibitin 1 (PHB1)	OTZNXYS2	PHB1_HUMAN	Decreases Expression	[5]
Myosin-10 (MYH10)	OTXN2WXS	MYH10_HUMAN	Decreases Expression	[5]
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL)	OTRO9RII	HMGCL_HUMAN	Increases Expression	[5]
Lon protease homolog, mitochondrial (LONP1)	OT665WYT	LONM_HUMAN	Increases Expression	[5]
Pigment epithelium-derived factor (SERPINF1)	OTWZH98J	PEDF_HUMAN	Increases Expression	[5]
Squalene synthase (FDFT1)	OTGDISIT	FDFT_HUMAN	Decreases Expression	[5]
Transgelin-2 (TAGLN2)	OTUXZGDQ	TAGL2_HUMAN	Decreases Expression	[5]
Stress-70 protein, mitochondrial (HSPA9)	OT4TMVS9	GRP75_HUMAN	Increases Expression	[5]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST)	OT39PDMS	OST48_HUMAN	Increases Expression	[5]
ADP-ribosylation factor-like protein 1 (ARL1)	OTB6N6BR	ARL1_HUMAN	Increases Expression	[5]
Replication factor C subunit 3 (RFC3)	OT1MS7AO	RFC3_HUMAN	Decreases Expression	[5]
Cyclin-F (CCNF)	OTJFVU43	CCNF_HUMAN	Decreases Expression	[5]
ETS translocation variant 5 (ETV5)	OTE2OBM4	ETV5_HUMAN	Decreases Expression	[5]
Peripherin (PRPH)	OT6VUH78	PERI_HUMAN	Increases Expression	[5]
Glycine--tRNA ligase (GARS1)	OT5B6R9Y	GARS_HUMAN	Increases Expression	[5]
Eukaryotic translation initiation factor 1 (EIF1)	OTB4GZ0V	EIF1_HUMAN	Increases Expression	[5]
Neutral amino acid transporter A (SLC1A4)	OTVODHAE	SATT_HUMAN	Increases Expression	[5]
Carnitine O-acetyltransferase (CRAT)	OTSCLZ04	CACP_HUMAN	Increases Expression	[5]
ETS translocation variant 4 (ETV4)	OT8C98UZ	ETV4_HUMAN	Decreases Expression	[5]
Ran-specific GTPase-activating protein (RANBP1)	OTQE226K	RANG_HUMAN	Decreases Expression	[5]
Peptidyl-prolyl cis-trans isomerase C (PPIC)	OTY5Q42N	PPIC_HUMAN	Increases Expression	[5]
Proliferation marker protein Ki-67 (MKI67)	OTA8N1QI	KI67_HUMAN	Decreases Expression	[5]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A)	OTDPS6AV	STT3A_HUMAN	Increases Expression	[5]
Retinaldehyde dehydrogenase 3 (ALDH1A3)	OT1C9NKQ	AL1A3_HUMAN	Decreases Expression	[5]
Sodium- and chloride-dependent glycine transporter 1 (SLC6A9)	OTHRUON2	SC6A9_HUMAN	Increases Expression	[5]
Prolyl endopeptidase (PREP)	OTSJZBB5	PPCE_HUMAN	Decreases Expression	[5]
ATP synthase F(0) complex subunit C3, mitochondrial (ATP5MC3)	OTX674BU	AT5G3_HUMAN	Decreases Expression	[5]
DNA-binding protein RFX5 (RFX5)	OT73KJ5P	RFX5_HUMAN	Decreases Expression	[5]
Coatomer subunit delta (ARCN1)	OTJ96STE	COPD_HUMAN	Increases Expression	[5]
Nestin (NES)	OTZ9PZ14	NEST_HUMAN	Decreases Expression	[5]
Aminomethyltransferase, mitochondrial (AMT)	OTQYEWZQ	GCST_HUMAN	Increases Expression	[5]
Histone H3-like centromeric protein A (CENPA)	OT0NEJ4X	CENPA_HUMAN	Decreases Expression	[5]
Serine--tRNA ligase, cytoplasmic (SARS1)	OTFKXQ1O	SYSC_HUMAN	Increases Expression	[5]
DNA replication licensing factor MCM2 (MCM2)	OTGGORIQ	MCM2_HUMAN	Decreases Expression	[5]
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL)	OT50L4XB	ACADV_HUMAN	Increases Expression	[5]
Transmembrane emp24 domain-containing protein 10 (TMED10)	OTUXSHH7	TMEDA_HUMAN	Increases Expression	[5]
Inactive serine/threonine-protein kinase 19 (STK19)	OTYM6437	STK19_HUMAN	Increases Expression	[5]
Isocitrate dehydrogenase subunit alpha, mitochondrial (IDH3A)	OT5QQB5L	IDH3A_HUMAN	Increases Expression	[5]
Serpin H1 (SERPINH1)	OTKGI7BS	SERPH_HUMAN	Increases Expression	[5]
Achaete-scute homolog 1 (ASCL1)	OTI4X44G	ASCL1_HUMAN	Increases Expression	[5]
Biotin--protein ligase (HLCS)	OTPDUX30	BPL1_HUMAN	Increases Expression	[5]
Death-associated protein 1 (DAP)	OT5YLL7E	DAP1_HUMAN	Increases Expression	[5]
Translocon-associated protein subunit delta (SSR4)	OTBWBGMR	SSRD_HUMAN	Increases Expression	[5]
Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1)	OTF3TBTK	SSDH_HUMAN	Decreases Expression	[5]
Lumican (LUM)	OTSRC874	LUM_HUMAN	Decreases Expression	[5]
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3)	OT4O4NFS	ROA3_HUMAN	Decreases Expression	[5]
Kinesin-like protein KIF11 (KIF11)	OTHRGLCQ	KIF11_HUMAN	Decreases Expression	[5]
Hexokinase-2 (HK2)	OTC0GCQO	HXK2_HUMAN	Decreases Expression	[5]
Large ribosomal subunit protein bL12m (MRPL12)	OTU41AM0	RM12_HUMAN	Decreases Expression	[5]
Thimet oligopeptidase (THOP1)	OT9E148D	THOP1_HUMAN	Decreases Expression	[5]
Tricarboxylate transport protein, mitochondrial (SLC25A1)	OTIDXQ9F	TXTP_HUMAN	Decreases Expression	[5]
CCAAT/enhancer-binding protein gamma (CEBPG)	OTGNAX3H	CEBPG_HUMAN	Increases Expression	[5]
Coatomer subunit alpha (COPA)	OTZ1DTXU	COPA_HUMAN	Increases Expression	[5]
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1)	OTYHXLWZ	BCAT1_HUMAN	Increases Expression	[5]
Adenylate kinase 2, mitochondrial (AK2)	OTZG3X2H	KAD2_HUMAN	Decreases Expression	[5]
Microfibril-associated glycoprotein 4 (MFAP4)	OT5W64QY	MFAP4_HUMAN	Increases Expression	[5]
Mesencephalic astrocyte-derived neurotrophic factor (MANF)	OT2AH8VJ	MANF_HUMAN	Increases Expression	[5]
Cadherin-15 (CDH15)	OTJ1TO02	CAD15_HUMAN	Increases Expression	[5]
Protein SEC13 homolog (SEC13)	OTSR4WWM	SEC13_HUMAN	Increases Expression	[5]
BH3-interacting domain death agonist (BID)	OTOSHSHU	BID_HUMAN	Decreases Expression	[5]
ATP synthase subunit f, mitochondrial (ATP5MF)	OTE4TBG9	ATPK_HUMAN	Decreases Expression	[5]
Homeobox protein DLX-5 (DLX5)	OTEEFBEU	DLX5_HUMAN	Decreases Expression	[5]
Methionine--tRNA ligase, cytoplasmic (MARS1)	OTLJ6MHJ	SYMC_HUMAN	Increases Expression	[5]
DNA polymerase epsilon subunit 2 (POLE2)	OTAC9V6L	DPOE2_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 alpha subcomplex subunit 6 (NDUFA6)	OTEOIIOL	NDUA6_HUMAN	Decreases Expression	[5]
Sestrin-2 (SESN2)	OT889IXY	SESN2_HUMAN	Increases Expression	[5]
Anthrax toxin receptor 2 (ANTXR2)	OTOGFGOJ	ANTR2_HUMAN	Increases Expression	[5]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (GNG2)	OT05Z3MC	GBG2_HUMAN	Decreases Expression	[5]
Triosephosphate isomerase (TPI1)	OT14KP4B	TPIS_HUMAN	Decreases Expression	[5]
Protein transport protein Sec61 subunit beta (SEC61B)	OTY1X6A2	SC61B_HUMAN	Increases Expression	[5]
Ribose-phosphate pyrophosphokinase 1 (PRPS1)	OTN3A6CN	PRPS1_HUMAN	Decreases Expression	[5]
Neurocalcin-delta (NCALD)	OTJZ8UEL	NCALD_HUMAN	Decreases Expression	[5]
10 kDa heat shock protein, mitochondrial (HSPE1)	OT7JSZLB	CH10_HUMAN	Decreases Expression	[5]
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1)	OTLBE3CB	S61A1_HUMAN	Increases Expression	[5]
Large ribosomal subunit protein eL37 (RPL37)	OTB6SDZ1	RL37_HUMAN	Increases Expression	[5]
LIM domain transcription factor LMO4 (LMO4)	OT5NDCT9	LMO4_HUMAN	Increases Expression	[5]
Estrogen-related receptor gamma (ESRRG)	OTC3A0KU	ERR3_HUMAN	Decreases Expression	[5]
Histone H4 (H4C1)	OTB71W46	H4_HUMAN	Increases Expression	[5]
Histone H2B type 1-C/E/F/G/I (H2BC10)	OTLQH0D6	H2B1C_HUMAN	Increases Expression	[5]
Inward rectifier potassium channel 2 (KCNJ2)	OT2OQEZS	KCNJ2_HUMAN	Increases Expression	[5]
Actin, cytoplasmic 2 (ACTG1)	OTH4V7VQ	ACTG_HUMAN	Decreases Expression	[5]
Thymosin beta-10 (TMSB10)	OTLVZ13T	TYB10_HUMAN	Decreases Expression	[5]
Disks large homolog 4 (DLG4)	OTD9E2LU	DLG4_HUMAN	Increases Expression	[5]
UDP-galactose translocator (SLC35A2)	OTQOTOWZ	S35A2_HUMAN	Increases Expression	[5]
Solute carrier family 35 member B1 (SLC35B1)	OTJ1MRN2	S35B1_HUMAN	Increases Expression	[5]
Arginase-2, mitochondrial (ARG2)	OTCPI0E8	ARGI2_HUMAN	Decreases Expression	[5]
ETS-related transcription factor Elf-3 (ELF3)	OTUTLEQO	ELF3_HUMAN	Decreases Expression	[5]
Nucleobindin-2 (NUCB2)	OTHO6JWN	NUCB2_HUMAN	Increases Expression	[5]
Protein delta homolog 1 (DLK1)	OTE1VLNB	DLK1_HUMAN	Decreases Expression	[5]
Brain acid soluble protein 1 (BASP1)	OTF4VS5G	BASP1_HUMAN	Decreases Expression	[5]
G-protein-signaling modulator 2 (GPSM2)	OT6RPMRM	GPSM2_HUMAN	Decreases Expression	[5]
TATA element modulatory factor (TMF1)	OT7JY7UF	TMF1_HUMAN	Increases Expression	[5]
Small ribosomal subunit protein mS25 (MRPS25)	OTN7IISS	RT25_HUMAN	Decreases Expression	[5]
Small ribosomal subunit protein bS6m (MRPS6)	OTKFY73U	RT06_HUMAN	Decreases Expression	[5]
Serine/arginine-rich splicing factor 3 (SRSF3)	OTOFT707	SRSF3_HUMAN	Decreases Expression	[5]
Tumor necrosis factor-inducible gene 6 protein (TNFAIP6)	OT1SLUZH	TSG6_HUMAN	Decreases Expression	[5]
Cytochrome c (CYCS)	OTBFALJD	CYC_HUMAN	Decreases Expression	[5]
Transcription factor A, mitochondrial (TFAM)	OTXXV5V7	TFAM_HUMAN	Decreases Expression	[5]
Solute carrier family 25 member 3 (SLC25A3)	OTAWGR4K	S25A3_HUMAN	Increases Expression	[5]
Transcription factor E2F1 (E2F1)	OTLKYBBC	E2F1_HUMAN	Decreases Expression	[5]
Serine/arginine-rich splicing factor 2 (SRSF2)	OTVDHO6U	SRSF2_HUMAN	Decreases Expression	[5]
N-acetylgalactosamine kinase (GALK2)	OTHR35JF	GALK2_HUMAN	Increases Expression	[5]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)	OTCO26FV	HMCS1_HUMAN	Decreases Expression	[5]
Large neutral amino acids transporter small subunit 1 (SLC7A5)	OT2WPVXD	LAT1_HUMAN	Increases Expression	[5]
ATP-dependent 6-phosphofructokinase, platelet type (PFKP)	OTFP7AA8	PFKAP_HUMAN	Decreases Expression	[5]
Cerebellar degeneration-related protein 2 (CDR2)	OTD3ZJST	CDR2_HUMAN	Increases Expression	[5]
A-kinase anchor protein 17A (AKAP17A)	OT2CEJW4	AK17A_HUMAN	Increases Expression	[5]
Myosin light chain 5 (MYL5)	OT7CQ24K	MYL5_HUMAN	Increases Expression	[5]
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase , mitochondrial (ALDH6A1)	OT8LCZCT	MMSA_HUMAN	Increases Expression	[5]
DNA-binding protein inhibitor ID-2 (ID2)	OT0U1D53	ID2_HUMAN	Increases Expression	[5]
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11)	OT7EVFBK	M2OM_HUMAN	Decreases Expression	[5]
Histone-lysine N-methyltransferase MECOM (MECOM)	OTP983W8	MECOM_HUMAN	Decreases Expression	[5]
Lamin-B2 (LMNB2)	OTXRDUOS	LMNB2_HUMAN	Decreases Expression	[5]
Glutamine--fructose-6-phosphate aminotransferase 1 (GFPT1)	OTQBDO45	GFPT1_HUMAN	Increases Expression	[5]
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP)	OTPYQX3K	C1QBP_HUMAN	Decreases Expression	[5]
Quinone oxidoreductase (CRYZ)	OTD2F4C8	QOR_HUMAN	Decreases Expression	[5]
Golgin subfamily A member 3 (GOLGA3)	OT27354E	GOGA3_HUMAN	Increases Expression	[5]
Golgin subfamily A member 2 (GOLGA2)	OT5S9KYM	GOGA2_HUMAN	Increases Expression	[5]
Testican-1 (SPOCK1)	OTLTDGK7	TICN1_HUMAN	Decreases Expression	[5]
Protoheme IX farnesyltransferase, mitochondrial (COX10)	OTCYIS0L	COX10_HUMAN	Increases Expression	[5]
Tyrosine-protein phosphatase non-receptor type 13 (PTPN13)	OTESFZSO	PTN13_HUMAN	Increases Expression	[5]
Heat shock protein 75 kDa, mitochondrial (TRAP1)	OTNG0L8J	TRAP1_HUMAN	Decreases Expression	[5]
TNF receptor-associated factor 2 (TRAF2)	OT1MEZZN	TRAF2_HUMAN	Decreases Expression	[5]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)	OT4SO7J4	BNIP3_HUMAN	Decreases Expression	[5]
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1)	OTA0UNHM	ECH1_HUMAN	Increases Expression	[5]
Chromatin assembly factor 1 subunit A (CHAF1A)	OTXSSY4H	CAF1A_HUMAN	Decreases Expression	[5]
Chromatin assembly factor 1 subunit B (CHAF1B)	OTOMK4KH	CAF1B_HUMAN	Decreases Expression	[5]
Syntaxin-5 (STX5)	OTQ0024B	STX5_HUMAN	Increases Expression	[5]
G protein pathway suppressor 2 (GPS2)	OT065FSS	GPS2_HUMAN	Increases Expression	[5]
Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1)	OTXNGZCG	MD2L1_HUMAN	Decreases Expression	[5]
Ras GTPase-activating protein-binding protein 1 (G3BP1)	OT7CJLY8	G3BP1_HUMAN	Decreases Expression	[5]
Protein OS-9 (OS9)	OTB5B2TY	OS9_HUMAN	Increases Expression	[5]
Limbic system-associated membrane protein (LSAMP)	OTYXVQX2	LSAMP_HUMAN	Increases Expression	[5]
Ras-related protein Rab-32 (RAB32)	OTTR4H7S	RAB32_HUMAN	Increases Expression	[5]
Mannosyl-oligosaccharide glucosidase (MOGS)	OT99MBGB	MOGS_HUMAN	Increases Expression	[5]
CD166 antigen (ALCAM)	OTCO4LP7	CD166_HUMAN	Increases Expression	[5]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2)	OTTUU92F	ENPP2_HUMAN	Decreases Expression	[5]
Methylglutaconyl-CoA hydratase, mitochondrial (AUH)	OT8VKBXX	AUHM_HUMAN	Increases Expression	[5]
Cytochrome c oxidase copper chaperone (COX17)	OTCP4LH2	COX17_HUMAN	Decreases Expression	[5]
Low-density lipoprotein receptor-related protein 8 (LRP8)	OTZ71YV2	LRP8_HUMAN	Decreases Expression	[5]
Malectin (MLEC)	OTOPGRF5	MLEC_HUMAN	Increases Expression	[5]
DNA polymerase alpha subunit B (POLA2)	OTTWQ73N	DPOA2_HUMAN	Decreases Expression	[5]
Dihydropyrimidinase-related protein 3 (DPYSL3)	OTINJV20	DPYL3_HUMAN	Decreases Expression	[5]
Transcription factor E2F2 (E2F2)	OTO75RM7	E2F2_HUMAN	Decreases Expression	[5]
Endonuclease G, mitochondrial (ENDOG)	OT5IM7B3	NUCG_HUMAN	Decreases Expression	[5]
Squalene monooxygenase (SQLE)	OT0GGRDO	ERG1_HUMAN	Decreases Expression	[5]
Protein disulfide-isomerase A5 (PDIA5)	OT76ZSX5	PDIA5_HUMAN	Increases Expression	[5]
DNA replication licensing factor MCM6 (MCM6)	OTKLIAWT	MCM6_HUMAN	Decreases Expression	[5]
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3)	OTGQ2AOJ	ITPR3_HUMAN	Decreases Expression	[5]
Maternal embryonic leucine zipper kinase (MELK)	OTEY2UQA	MELK_HUMAN	Decreases Expression	[5]
Neutral alpha-glucosidase AB (GANAB)	OTYLXY4M	GANAB_HUMAN	Increases Expression	[5]
Raftlin (RFTN1)	OT8875JE	RFTN1_HUMAN	Decreases Expression	[5]
Major vault protein (MVP)	OTJGHJRB	MVP_HUMAN	Increases Expression	[5]
PCNA-associated factor (PCLAF)	OTMVIOUU	PAF15_HUMAN	Decreases Expression	[5]
Signal peptidase complex subunit 2 (SPCS2)	OTCGTTLY	SPCS2_HUMAN	Increases Expression	[5]
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1)	OT9EROL6	HERP1_HUMAN	Increases Expression	[5]
Leucine--tRNA ligase, mitochondrial (LARS2)	OTJS37LE	SYLM_HUMAN	Decreases Expression	[5]
Mitochondrial inner membrane protein OXA1L (OXA1L)	OTS0BFRD	OXA1L_HUMAN	Increases Expression	[5]
Protein disulfide-isomerase A6 (PDIA6)	OT8YBR17	PDIA6_HUMAN	Increases Expression	[5]
kinase isozyme 2, mitochondrial (PDK2)	OTM436F9	PDK2_HUMAN	Increases Expression	[5]
kinase isozyme 3, mitochondrial (PDK3)	OTCPSTID	PDK3_HUMAN	Decreases Expression	[5]
Serum paraoxonase/arylesterase 2 (PON2)	OT55NCTD	PON2_HUMAN	Decreases Expression	[5]
Reticulocalbin-1 (RCN1)	OT3JBGAG	RCN1_HUMAN	Increases Expression	[5]
Transmembrane emp24 domain-containing protein 2 (TMED2)	OTBLO7RW	TMED2_HUMAN	Increases Expression	[5]
Mitochondrial fission regulator 1 (MTFR1)	OTLB1VFT	MTFR1_HUMAN	Increases Expression	[5]
Delta(24)-sterol reductase (DHCR24)	OTP301JW	DHC24_HUMAN	Decreases Expression	[5]
Disks large-associated protein 5 (DLGAP5)	OTWCN39U	DLGP5_HUMAN	Decreases Expression	[5]
Calponin-3 (CNN3)	OTJTAXAP	CNN3_HUMAN	Decreases Expression	[5]
Protein transport protein Sec23A (SEC23A)	OTBRNIJ3	SC23A_HUMAN	Increases Expression	[5]
SH2 domain-containing adapter protein B (SHB)	OTF2HSC0	SHB_HUMAN	Decreases Expression	[5]
Surfeit locus protein 1 (SURF1)	OTAINRSS	SURF1_HUMAN	Increases Expression	[5]
Transcriptional enhancer factor TEF-4 (TEAD2)	OTM8YMYT	TEAD2_HUMAN	Decreases Expression	[5]
Translocating chain-associated membrane protein 1 (TRAM1)	OT3I0H8E	TRAM1_HUMAN	Increases Expression	[5]
Mitochondrial import receptor subunit TOM34 (TOMM34)	OTH6MITE	TOM34_HUMAN	Decreases Expression	[5]
Methylsterol monooxygenase 1 (MSMO1)	OTKV62RZ	MSMO1_HUMAN	Decreases Expression	[5]
Proline-rich protein 4 (PRR4)	OT26I382	PROL4_HUMAN	Increases Expression	[5]
Neuronatin (NNAT)	OTNRLO7G	NNAT_HUMAN	Decreases Expression	[5]
Cryptochrome-1 (CRY1)	OTTGAJT0	CRY1_HUMAN	Decreases Expression	[5]
Cysteine and glycine-rich protein 2 (CSRP2)	OT4SW0HI	CSRP2_HUMAN	Decreases Expression	[5]
Large ribosomal subunit protein uL23m (MRPL23)	OT7H7PM2	RM23_HUMAN	Decreases Expression	[5]
Atypical chemokine receptor 1 (ACKR1)	OT9M11LX	ACKR1_HUMAN	Increases Expression	[5]
Neuronal regeneration-related protein (NREP)	OT2AZPKK	NREP_HUMAN	Decreases Expression	[5]
Serine/arginine-rich splicing factor 7 (SRSF7)	OTRS4W4S	SRSF7_HUMAN	Decreases Expression	[5]
Nuclear respiratory factor 1 (NRF1)	OTOXWNV8	NRF1_HUMAN	Decreases Expression	[5]
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP)	OTEPHG0S	CLPP_HUMAN	Increases Expression	[5]
Thiosulfate sulfurtransferase (TST)	OTZ4F5LK	THTR_HUMAN	Increases Expression	[5]
NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial (NDUFA9)	OTMKQJJ8	NDUA9_HUMAN	Decreases Expression	[5]
Phosphoenolpyruvate carboxykinase , mitochondrial (PCK2)	OTJ8LX4N	PCKGM_HUMAN	Decreases Expression	[5]
Dual specificity protein phosphatase 6 (DUSP6)	OT4H6RKW	DUS6_HUMAN	Decreases Expression	[5]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)	OT25JBA3	F263_HUMAN	Decreases Expression	[5]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4)	OTQYEXL2	F264_HUMAN	Decreases Expression	[5]
DNA excision repair protein ERCC-6-like (ERCC6L)	OTE9V7D9	ERC6L_HUMAN	Decreases Expression	[5]
Prolyl 3-hydroxylase 1 (P3H1)	OT2TFW25	P3H1_HUMAN	Increases Expression	[5]
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (PAN2)	OTB65N2I	PAN2_HUMAN	Increases Expression	[5]
Fibronectin type III domain-containing protein 3B (FNDC3B)	OTBILGDR	FND3B_HUMAN	Increases Expression	[5]
BolA-like protein 3 (BOLA3)	OTDEDY0S	BOLA3_HUMAN	Decreases Expression	[5]
Protein Largen (PRR16)	OTG4TEGR	LARGN_HUMAN	Decreases Expression	[5]
Sigma intracellular receptor 2 (TMEM97)	OTH76ZWK	SGMR2_HUMAN	Decreases Expression	[5]
BEN domain-containing protein 6 (BEND6)	OTF6H1TJ	BEND6_HUMAN	Increases Expression	[5]
All trans-polyprenyl-diphosphate synthase PDSS1 (PDSS1)	OTXGVHAB	DPS1_HUMAN	Decreases Expression	[5]
KN motif and ankyrin repeat domain-containing protein 4 (KANK4)	OT5WC0Q8	KANK4_HUMAN	Increases Expression	[5]
Lysophospholipase-like protein 1 (LYPLAL1)	OT8F2DCV	LYPL1_HUMAN	Increases Expression	[5]
KN motif and ankyrin repeat domain-containing protein 2 (KANK2)	OT3SZIWM	KANK2_HUMAN	Decreases Expression	[5]
Tensin-3 (TNS3)	OTPG2D8Z	TENS3_HUMAN	Decreases Expression	[5]
Rhomboid domain-containing protein 2 (RHBDD2)	OTX54ILM	RHBD2_HUMAN	Increases Expression	[5]
Magnesium transporter NIPA3 (NIPAL1)	OTRYI60X	NIPA3_HUMAN	Decreases Expression	[5]
Fidgetin-like protein 1 (FIGNL1)	OTKII63K	FIGL1_HUMAN	Decreases Expression	[5]
ATPase family AAA domain-containing protein 2 (ATAD2)	OT8MCRNY	ATAD2_HUMAN	Decreases Expression	[5]
Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC1S2)	OTUR3E76	BL1S2_HUMAN	Increases Expression	[5]
Coiled-coil domain-containing protein 171 (CCDC171)	OT9NL2D9	CC171_HUMAN	Decreases Expression	[5]
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L)	OTV01EFP	C1TM_HUMAN	Increases Expression	[5]
Protein disulfide isomerase CRELD2 (CRELD2)	OTL73AO8	CREL2_HUMAN	Increases Expression	[5]
Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2)	OTUJZIDC	ISLR2_HUMAN	Decreases Expression	[5]
Zinc finger protein basonuclin-2 (BNC2)	OTU22H9Z	BNC2_HUMAN	Decreases Expression	[5]
LHFPL tetraspan subfamily member 2 protein (LHFPL2)	OTDWEEBQ	LHPL2_HUMAN	Decreases Expression	[5]
Patatin-like phospholipase domain-containing protein 7 (PNPLA7)	OT5VSJX2	PLPL7_HUMAN	Increases Expression	[5]
Cytochrome P450 4V2 (CYP4V2)	OTQKNK0D	CP4V2_HUMAN	Increases Expression	[5]
Acyl-CoA dehydrogenase family member 11 (ACAD11)	OT3T9HAX	ACD11_HUMAN	Increases Expression	[5]
Cyclic AMP-responsive element-binding protein 3-like protein 2 (CREB3L2)	OT09MHV0	CR3L2_HUMAN	Increases Expression	[5]
Centromere protein U (CENPU)	OTQ4TZRS	CENPU_HUMAN	Decreases Expression	[5]
Ribosomal protein eS27-like (RPS27L)	OTZWHU0N	RS27L_HUMAN	Increases Expression	[5]
Staphylococcal nuclease domain-containing protein 1 (SND1)	OTT734JN	SND1_HUMAN	Increases Expression	[5]
Protein MCM10 homolog (MCM10)	OTV0O3JN	MCM10_HUMAN	Decreases Expression	[5]
Histone H2A type 3 (H2AC25)	OTPO62JI	H2A3_HUMAN	Increases Expression	[5]
Endonuclease/exonuclease/phosphatase family domain-containing protein 1 (EEPD1)	OTTOGO05	EEPD1_HUMAN	Decreases Expression	[5]
Carbohydrate sulfotransferase 15 (CHST15)	OTNTM2SP	CHSTF_HUMAN	Increases Expression	[5]
Proton-coupled amino acid transporter 1 (SLC36A1)	OTIEL5QZ	S36A1_HUMAN	Decreases Expression	[5]
Treslin (TICRR)	OT2HKWOC	TICRR_HUMAN	Decreases Expression	[5]
D-glutamate cyclase, mitochondrial (DGLUCY)	OTZD17IM	GLUCM_HUMAN	Decreases Expression	[5]
Protein MON2 homolog (MON2)	OTCSVMAR	MON2_HUMAN	Increases Expression	[5]
Protein ADM2 (ADM2)	OTJVN41C	ADM2_HUMAN	Increases Expression	[5]
Microtubule organization protein AKNA (AKNA)	OTQ6E2C8	AKNA_HUMAN	Increases Expression	[5]
Pleckstrin homology domain-containing family H member 3 (PLEKHH3)	OTREOQBO	PKHH3_HUMAN	Increases Expression	[5]
E3 ubiquitin-protein ligase synoviolin (SYVN1)	OTZ4ZJP5	SYVN1_HUMAN	Increases Expression	[5]
Suppressor APC domain-containing protein 2 (SAPCD2)	OTXS0EXM	SAPC2_HUMAN	Decreases Expression	[5]
Four-jointed box protein 1 (FJX1)	OT8SVTSS	FJX1_HUMAN	Decreases Expression	[5]
Poly(ADP-ribose) glycohydrolase (PARG)	OT10JTIO	PARG_HUMAN	Decreases Expression	[5]
RNA-binding protein MEX3D (MEX3D)	OTAUWRK7	MEX3D_HUMAN	Decreases Expression	[5]
TIR domain-containing adapter molecule 2 (TICAM2)	OTK7GIJ5	TCAM2_HUMAN	Increases Expression	[5]
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11)	OTZXD1UK	NDUAB_HUMAN	Decreases Expression	[5]
ERO1-like protein beta (ERO1B)	OTHZ25Y8	ERO1B_HUMAN	Increases Expression	[5]
Cerebellin-2 (CBLN2)	OT29SSBE	CBLN2_HUMAN	Decreases Expression	[5]
Protein HID1 (HID1)	OTVJIFSU	HID1_HUMAN	Increases Expression	[5]
Iron-sulfur cluster co-chaperone protein HscB (HSCB)	OTP8YV25	HSC20_HUMAN	Increases Expression	[5]
Hydroxyacid-oxoacid transhydrogenase, mitochondrial (ADHFE1)	OT8J2PD8	HOT_HUMAN	Increases Expression	[5]
DNA damage-induced apoptosis suppressor protein (DDIAS)	OTTGG2PM	DDIAS_HUMAN	Decreases Expression	[5]
Intraflagellar transport protein 20 homolog (IFT20)	OTKJS2BZ	IFT20_HUMAN	Increases Expression	[5]
Structure-specific endonuclease subunit SLX4 (SLX4)	OTF6236I	SLX4_HUMAN	Decreases Expression	[5]
Stabilizer of axonemal microtubules 1 (SAXO1)	OT7M6PLA	SAXO1_HUMAN	Increases Expression	[5]
Chondroitin sulfate synthase 2 (CHPF)	OTLMP2VY	CHSS2_HUMAN	Increases Expression	[5]
Transcription initiation factor TFIID subunit 1-like (TAF1L)	OT9Z7EVA	TAF1L_HUMAN	Increases Expression	[5]
Putative ribosome-binding factor A, mitochondrial (RBFA)	OT69B0D9	RBFA_HUMAN	Decreases Expression	[5]
Probable phosphoglycerate mutase 4 (PGAM4)	OT7WZRD0	PGAM4_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 alpha subcomplex assembly factor 2 (NDUFAF2)	OTC8QPRS	NDUF2_HUMAN	Increases Expression	[5]
Homeobox protein SIX5 (SIX5)	OTT1I9WY	SIX5_HUMAN	Increases Expression	[5]
Zinc transporter ZIP11 (SLC39A11)	OT71LCT2	S39AB_HUMAN	Increases Expression	[5]
Protein FAM24B (FAM24B)	OTN9XBAM	FA24B_HUMAN	Increases Expression	[5]
Keratinocyte-associated protein 2 (KRTCAP2)	OTRV6ORJ	KTAP2_HUMAN	Increases Expression	[5]
Sodium-dependent lysophosphatidylcholine symporter 1 (MFSD2A)	OTVG1VG0	NLS1_HUMAN	Decreases Expression	[5]
Neuropilin and tolloid-like protein 2 (NETO2)	OT0YAMC0	NETO2_HUMAN	Decreases Expression	[5]
Transmembrane protein 116 (TMEM116)	OTYDSA49	TM116_HUMAN	Increases Expression	[5]
Liprin-beta-2 (PPFIBP2)	OTXQO55Y	LIPB2_HUMAN	Decreases Expression	[5]
Probable aminopeptidase NPEPL1 (NPEPL1)	OTMJF2RB	PEPL1_HUMAN	Increases Expression	[5]
Phospholipid phosphatase 5 (PLPP5)	OTHT51D6	PLPP5_HUMAN	Increases Expression	[5]
Atypical kinase COQ8A, mitochondrial (COQ8A)	OT1ETSA2	COQ8A_HUMAN	Increases Expression	[5]
GrpE protein homolog 2, mitochondrial (GRPEL2)	OTNF289O	GRPE2_HUMAN	Increases Expression	[5]
Gasdermin-B (GSDMB)	OTWA7P10	GSDMB_HUMAN	Increases Expression	[5]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Increases Expression	[5]
Golgin subfamily A member 5 (GOLGA5)	OTG6HB6U	GOGA5_HUMAN	Increases Expression	[5]
Guanine nucleotide exchange factor for Rab-3A (RAB3IL1)	OT18H5HD	R3GEF_HUMAN	Increases Expression	[5]
Mitochondria-eating protein (SPATA18)	OTOEHTHU	MIEAP_HUMAN	Increases Expression	[5]
Palmitoyl thioesterase CPT1C (CPT1C)	OT8F1MBF	CPT1C_HUMAN	Increases Expression	[5]
Minor histocompatibility antigen H13 (HM13)	OTGEO1LP	HM13_HUMAN	Increases Expression	[5]
Alanine aminotransferase 2 (GPT2)	OTS5VF7N	ALAT2_HUMAN	Increases Expression	[5]
Hepatitis A virus cellular receptor 2 (HAVCR2)	OTOL603T	HAVR2_HUMAN	Increases Expression	[5]
Volume-regulated anion channel subunit LRRC8C (LRRC8C)	OT2Y51BP	LRC8C_HUMAN	Decreases Expression	[5]
Protein Shroom3 (SHROOM3)	OTQKC5X2	SHRM3_HUMAN	Decreases Expression	[5]
Conserved oligomeric Golgi complex subunit 1 (COG1)	OT3JSAF7	COG1_HUMAN	Increases Expression	[5]
Cholinephosphotransferase 1 (CHPT1)	OT4FJ0K3	CHPT1_HUMAN	Increases Expression	[5]
DEP domain-containing protein 1B (DEPDC1B)	OTMVFOT1	DEP1B_HUMAN	Decreases Expression	[5]
Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8)	OT9HT0O1	NUDT8_HUMAN	Decreases Expression	[5]
RNA polymerase-associated protein LEO1 (LEO1)	OTAPF4PA	LEO1_HUMAN	Decreases Expression	[5]
Cytoglobin (CYGB)	OTX153DQ	CYGB_HUMAN	Decreases Expression	[5]
Protein phosphatase 1E (PPM1E)	OTXRH3YA	PPM1E_HUMAN	Decreases Expression	[5]
Transmembrane protein 158 (TMEM158)	OT0KUBBI	TM158_HUMAN	Decreases Expression	[5]
Transcription factor AP-2-beta (TFAP2B)	OTR1T8E9	AP2B_HUMAN	Decreases Expression	[5]
ER degradation-enhancing alpha-mannosidase-like protein 1 (EDEM1)	OTWHN69S	EDEM1_HUMAN	Increases Expression	[5]
Nuclear pore complex protein Nup205 (NUP205)	OTJKHCY6	NU205_HUMAN	Decreases Expression	[5]
GPI-anchor transamidase (PIGK)	OTAFSYLD	GPI8_HUMAN	Increases Expression	[5]
DNA repair and recombination protein RAD54-like (RAD54L)	OTEGMAKG	RAD54_HUMAN	Decreases Expression	[5]
Zinc finger protein neuro-d4 (DPF1)	OTI4ZFP8	DPF1_HUMAN	Decreases Expression	[5]
NEDD4-binding protein 2-like 2 (N4BP2L2)	OTV2F04G	N42L2_HUMAN	Increases Expression	[5]
Bcl2-associated agonist of cell death (BAD)	OT63ERYM	BAD_HUMAN	Increases Expression	[5]
Glutaryl-CoA dehydrogenase, mitochondrial (GCDH)	OTVQMZZN	GCDH_HUMAN	Decreases Expression	[5]
Rho guanine nucleotide exchange factor 2 (ARHGEF2)	OTBQTFRT	ARHG2_HUMAN	Increases Expression	[5]
Interferon regulatory factor 7 (IRF7)	OTC1A2PQ	IRF7_HUMAN	Increases Expression	[5]
Histone H2A type 1-C (H2AC6)	OTF3YK7V	H2A1C_HUMAN	Increases Expression	[5]
Myeloid-derived growth factor (MYDGF)	OT9HRPL6	MYDGF_HUMAN	Increases Expression	[5]
F-box only protein 32 (FBXO32)	OTUE978R	FBX32_HUMAN	Increases Expression	[5]
DNA topoisomerase I, mitochondrial (TOP1MT)	OT2H77ID	TOP1M_HUMAN	Increases Expression	[5]
Ras-related protein Rab-24 (RAB24)	OTOFNAJK	RAB24_HUMAN	Increases Expression	[5]
Mitochondrial amidoxime reducing component 2 (MTARC2)	OT8B6LVD	MARC2_HUMAN	Increases Expression	[5]
Transcription factor E2F7 (E2F7)	OTWW358N	E2F7_HUMAN	Decreases Expression	[5]
FGGY carbohydrate kinase domain-containing protein (FGGY)	OTLNEC2X	FGGY_HUMAN	Increases Expression	[5]
Inactive rhomboid protein 1 (RHBDF1)	OTCQ7UDS	RHDF1_HUMAN	Increases Expression	[5]
Isochorismatase domain-containing protein 1 (ISOC1)	OTAO7Z87	ISOC1_HUMAN	Decreases Expression	[5]
Methyl-CpG-binding domain protein 6 (MBD6)	OTDHBSFS	MBD6_HUMAN	Increases Expression	[5]
Methionyl-tRNA formyltransferase, mitochondrial (MTFMT)	OT1OIVJL	FMT_HUMAN	Decreases Expression	[5]
Mitochondrial glycine transporter (SLC25A38)	OTP4WXFU	S2538_HUMAN	Increases Expression	[5]
Ribosome-recycling factor, mitochondrial (MRRF)	OT6AHPVG	RRFM_HUMAN	Increases Expression	[5]
RecQ-mediated genome instability protein 2 (RMI2)	OTA0HP4S	RMI2_HUMAN	Decreases Expression	[5]
Sperm acrosome-associated protein 9 (SPACA9)	OTVRFX49	SACA9_HUMAN	Increases Expression	[5]
RNA-binding protein 33 (RBM33)	OT4JQ9YG	RBM33_HUMAN	Increases Expression	[5]
Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2)	OTUVR2OO	DC2I2_HUMAN	Decreases Expression	[5]
DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3)	OT61924T	DNJA3_HUMAN	Increases Expression	[5]
AMSH-like protease (STAMBPL1)	OTI4CYTF	STALP_HUMAN	Increases Expression	[5]
Diphosphoinositol polyphosphate phosphohydrolase 3-beta (NUDT11)	OTFDXJA1	NUD11_HUMAN	Decreases Expression	[5]
Chronophin (PDXP)	OTZ7GN95	PLPP_HUMAN	Decreases Expression	[5]
Aurora kinase B (AURKB)	OTIY4VHU	AURKB_HUMAN	Decreases Expression	[5]
Cell division cycle-associated 7-like protein (CDCA7L)	OT1FFWKC	CDA7L_HUMAN	Decreases Expression	[5]
RUS family member 1 (RUSF1)	OTRIIY6J	RUSF1_HUMAN	Increases Expression	[5]
Serine/threonine-protein kinase greatwall (MASTL)	OTQ7YKK5	GWL_HUMAN	Decreases Expression	[5]
Protein disulfide isomerase CRELD1 (CRELD1)	OTBSPZFP	CREL1_HUMAN	Increases Expression	[5]
Transcription cofactor HES-6 (HES6)	OTWO5SCF	HES6_HUMAN	Decreases Expression	[5]
Mannose-1-phosphate guanyltransferase alpha (GMPPA)	OTADC03N	GMPPA_HUMAN	Increases Expression	[5]
Conserved oligomeric Golgi complex subunit 3 (COG3)	OTKJMB1Q	COG3_HUMAN	Increases Expression	[5]
Coiled-coil domain-containing protein 74B (CCDC74B)	OTTRSGJR	CC74B_HUMAN	Increases Expression	[5]
Dynein heavy chain domain-containing protein 1 (DNHD1)	OT4U3HUW	DNHD1_HUMAN	Increases Expression	[5]
Protein phosphatase 1M (PPM1M)	OTCPLZQ7	PPM1M_HUMAN	Increases Expression	[5]
Sideroflexin-2 (SFXN2)	OTRFKK0G	SFXN2_HUMAN	Decreases Expression	[5]
Methylmalonyl-CoA epimerase, mitochondrial (MCEE)	OTTJP3GM	MCEE_HUMAN	Increases Expression	[5]
Bcl-2-binding component 3, isoforms 3/4 (BBC3)	OTUAXDAY	BBC3B_HUMAN	Increases Expression	[5]
Small integral membrane protein 14 (SMIM14)	OT47IF19	SIM14_HUMAN	Increases Expression	[5]
Sperm-associated antigen 5 (SPAG5)	OTCLJ56M	SPAG5_HUMAN	Decreases Expression	[5]
Elongation factor G, mitochondrial (GFM1)	OTUN4V3N	EFGM_HUMAN	Decreases Expression	[5]
Tribbles homolog 3 (TRIB3)	OTG5OS7X	TRIB3_HUMAN	Increases Expression	[5]
Chloride channel CLIC-like protein 1 (CLCC1)	OTTXCXVT	CLCC1_HUMAN	Increases Expression	[5]
Protein phosphatase 1 regulatory inhibitor subunit 16B (PPP1R16B)	OTZJFX5C	PP16B_HUMAN	Decreases Expression	[5]
Insulinoma-associated protein 2 (INSM2)	OTNMQUZV	INSM2_HUMAN	Decreases Expression	[5]
c-Myc-binding protein (MYCBP)	OT4IZR4R	MYCBP_HUMAN	Decreases Expression	[5]
26S proteasome non-ATPase regulatory subunit 1 (PSMD1)	OTW258OV	PSMD1_HUMAN	Decreases Expression	[5]
M-phase phosphoprotein 6 (MPHOSPH6)	OT6E2S48	MPH6_HUMAN	Decreases Expression	[5]
Ribonucleases P/MRP protein subunit POP1 (POP1)	OTBIYMJ0	POP1_HUMAN	Decreases Expression	[5]
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1)	OTYRXD2T	PMYT1_HUMAN	Decreases Expression	[5]
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC)	OTC8G2MX	C560_HUMAN	Decreases Expression	[5]
G-protein coupled receptor 22 (GPR22)	OTHTSAJI	GPR22_HUMAN	Increases Expression	[5]
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10)	OT7RJON4	HCD2_HUMAN	Decreases Expression	[5]
ATP synthase subunit s, mitochondrial (DMAC2L)	OT2OQ1UD	ATP5S_HUMAN	Decreases Expression	[5]
Transmembrane 9 superfamily member 2 (TM9SF2)	OTA0C202	TM9S2_HUMAN	Increases Expression	[5]
Endothelial PAS domain-containing protein 1 (EPAS1)	OTRE3O8U	EPAS1_HUMAN	Decreases Expression	[5]
Growth/differentiation factor 15 (GDF15)	OTWQN50N	GDF15_HUMAN	Increases Expression	[5]
Protein NipSnap homolog 1 (NIPSNAP1)	OTKXKUT8	NIPS1_HUMAN	Decreases Expression	[5]
Condensin complex subunit 3 (NCAPG)	OT1AI9EO	CND3_HUMAN	Decreases Expression	[5]
Ribosome quality control complex subunit TCF25 (TCF25)	OTTFHHU9	TCF25_HUMAN	Increases Expression	[5]
La-related protein 6 (LARP6)	OTUQ9QS9	LARP6_HUMAN	Increases Expression	[5]
Sugar transporter SWEET1 (SLC50A1)	OTF1DT72	SWET1_HUMAN	Increases Expression	[5]
Endoplasmic reticulum resident protein 44 (ERP44)	OT7ZI7AG	ERP44_HUMAN	Increases Expression	[5]
Endosomal/lysosomal proton channel TMEM175 (TMEM175)	OT6DUIYC	TM175_HUMAN	Increases Expression	[5]
Protein PIMREG (PIMREG)	OTKC8T3E	PIMRE_HUMAN	Decreases Expression	[5]
Synaptotagmin-17 (SYT17)	OTTW4MI3	SYT17_HUMAN	Increases Expression	[5]
Transmembrane protein 70, mitochondrial (TMEM70)	OTLTKYXG	TMM70_HUMAN	Decreases Expression	[5]
Brain-enriched guanylate kinase-associated protein (BEGAIN)	OTT3UD2K	BEGIN_HUMAN	Decreases Expression	[5]
Dual specificity protein phosphatase 26 (DUSP26)	OTI7WIYN	DUS26_HUMAN	Increases Expression	[5]
Protein adenylyltransferase FICD (FICD)	OT2R9ZXW	FICD_HUMAN	Increases Expression	[5]
Sister chromatid cohesion protein DCC1 (DSCC1)	OTPUVLZT	DCC1_HUMAN	Decreases Expression	[5]
Transmembrane emp24 domain-containing protein 9 (TMED9)	OTYGAQS0	TMED9_HUMAN	Increases Expression	[5]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2)	OTZ092ZJ	THIC_HUMAN	Decreases Expression	[5]
Cell division cycle-associated protein 7 (CDCA7)	OT12HDZY	CDCA7_HUMAN	Decreases Expression	[5]
Receptor for retinol uptake STRA6 (STRA6)	OT2IDF27	STRA6_HUMAN	Decreases Expression	[5]
Rab11 family-interacting protein 5 (RAB11FIP5)	OTNA33DE	RFIP5_HUMAN	Increases Expression	[5]
Serine/threonine-protein kinase PINK1, mitochondrial (PINK1)	OT50NR57	PINK1_HUMAN	Increases Expression	[5]
Nucleolar and spindle-associated protein 1 (NUSAP1)	OT85HIJ5	NUSAP_HUMAN	Decreases Expression	[5]
Eukaryotic translation initiation factor 2A (EIF2A)	OTWXELQP	EIF2A_HUMAN	Increases Expression	[5]
Signal peptidase complex catalytic subunit SEC11C (SEC11C)	OTP3WS0U	SC11C_HUMAN	Increases Expression	[5]
Large ribosomal subunit protein uL13m (MRPL13)	OT6D8Y9G	RM13_HUMAN	Decreases Expression	[5]
Large ribosomal subunit protein uL1m (MRPL1)	OT3YIQIA	RM01_HUMAN	Increases Expression	[5]
Probable mitochondrial glutathione transporter SLC25A39 (SLC25A39)	OTO7WA10	S2539_HUMAN	Decreases Expression	[5]
Derlin-2 (DERL2)	OTI3TUUZ	DERL2_HUMAN	Increases Expression	[5]
Protein FAM107B (FAM107B)	OT5RG4J0	F107B_HUMAN	Increases Expression	[5]
Enkurin domain-containing protein 1 (ENKD1)	OT5YE5D5	ENKD1_HUMAN	Increases Expression	[5]
Large ribosomal subunit protein uL18m (MRPL18)	OTORKKYC	RM18_HUMAN	Decreases Expression	[5]
Nucleotide exchange factor SIL1 (SIL1)	OTDI85I5	SIL1_HUMAN	Increases Expression	[5]
Iron-sulfur cluster assembly enzyme ISCU (ISCU)	OTSW6DQP	ISCU_HUMAN	Increases Expression	[5]
Caspase recruitment domain-containing protein 9 (CARD9)	OTJ81AWD	CARD9_HUMAN	Increases Expression	[5]
Sodium-coupled neutral amino acid symporter 1 (SLC38A1)	OTO3VD5E	S38A1_HUMAN	Increases Expression	[5]
Diphthine methyl ester synthase (DPH5)	OT9UKOPV	DPH5_HUMAN	Increases Expression	[5]
Golgi resident protein GCP60 (ACBD3)	OTMYNY7A	GCP60_HUMAN	Increases Expression	[5]
Protein FAM83D (FAM83D)	OTQWZ1UO	FA83D_HUMAN	Decreases Expression	[5]
Ribosomal oxygenase 1 (RIOX1)	OTN41QXP	RIOX1_HUMAN	Decreases Expression	[5]
dCTP pyrophosphatase 1 (DCTPP1)	OTP1GZYF	DCTP1_HUMAN	Decreases Expression	[5]
Complex I assembly factor ACAD9, mitochondrial (ACAD9)	OT4HITJ6	ACAD9_HUMAN	Decreases Expression	[5]
Mitochondrial glutamate carrier 1 (SLC25A22)	OTQGVI1N	GHC1_HUMAN	Decreases Expression	[5]
RecQ-mediated genome instability protein 1 (RMI1)	OT1ZVTFL	RMI1_HUMAN	Decreases Expression	[5]
GrpE protein homolog 1, mitochondrial (GRPEL1)	OT8O00YJ	GRPE1_HUMAN	Decreases Expression	[5]
Kinetochore protein Spc25 (SPC25)	OTCAS0OH	SPC25_HUMAN	Decreases Expression	[5]
Popeye domain-containing protein 2 (POPDC2)	OTDAZSY5	POPD2_HUMAN	Decreases Expression	[5]
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2)	OTQDHSMI	MCCB_HUMAN	Decreases Expression	[5]
Stromal cell-derived factor 2-like protein 1 (SDF2L1)	OTE7JIO2	SDF2L_HUMAN	Increases Expression	[5]
Receptor-type tyrosine-protein phosphatase H (PTPRH)	OTDUHQGF	PTPRH_HUMAN	Increases Expression	[5]
Homeobox protein HMX1 (HMX1)	OT65ZGE0	HMX1_HUMAN	Decreases Expression	[5]
ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3)	OT2G3KCG	ARFG3_HUMAN	Increases Expression	[5]
E3 ubiquitin-protein ligase CCNB1IP1 (CCNB1IP1)	OTOTVMC8	CIP1_HUMAN	Increases Expression	[5]
Acyl-coenzyme A thioesterase 13 (ACOT13)	OTWRUST1	ACO13_HUMAN	Decreases Expression	[5]
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1)	OTIK4I5R	TIDC1_HUMAN	Increases Expression	[5]
Leucine zipper transcription factor-like protein 1 (LZTFL1)	OTIEIOEW	LZTL1_HUMAN	Increases Expression	[5]
Nectin-3 (NECTIN3)	OTS8N7MK	NECT3_HUMAN	Increases Expression	[5]
Dual specificity tyrosine-phosphorylation-regulated kinase 4 (DYRK4)	OTO9ZBI5	DYRK4_HUMAN	Increases Expression	[5]
Diablo IAP-binding mitochondrial protein (DIABLO)	OTHJ9MCZ	DBLOH_HUMAN	Increases Expression	[5]
Sialic acid synthase (NANS)	OTMQ2FUH	SIAS_HUMAN	Increases Expression	[5]
Oligosaccharyltransferase complex subunit OSTC (OSTC)	OTT0823Y	OSTC_HUMAN	Increases Expression	[5]
Carbonic anhydrase-related protein 10 (CA10)	OTC3N1F6	CAH10_HUMAN	Decreases Expression	[5]
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3)	OTMEF544	SIR3_HUMAN	Decreases Expression	[5]
RNA-binding protein 12 (RBM12)	OTQYZ3LQ	RBM12_HUMAN	Decreases Expression	[5]
Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)	OTORNUIF	STAU2_HUMAN	Decreases Expression	[5]
Transmembrane protein 100 (TMEM100)	OTRJ6OHY	TM100_HUMAN	Decreases Expression	[5]
Fanconi anemia group I protein (FANCI)	OTW8E3SC	FANCI_HUMAN	Decreases Expression	[5]
Guanine nucleotide-binding protein-like 3-like protein (GNL3L)	OTZYEFST	GNL3L_HUMAN	Increases Expression	[5]
Histone chaperone ASF1B (ASF1B)	OTKXX12I	ASF1B_HUMAN	Decreases Expression	[5]
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB)	OTXLLSIZ	MCUB_HUMAN	Decreases Expression	[5]
Very long chain fatty acid elongase 2 (ELOVL2)	OTDAF6U3	ELOV2_HUMAN	Decreases Expression	[5]
Voltage-dependent calcium channel subunit alpha-2/delta-2 (CACNA2D2)	OTFJXVQQ	CA2D2_HUMAN	Decreases Expression	[5]
Peptidyl-prolyl cis-trans isomerase FKBP11 (FKBP11)	OTY2GC67	FKB11_HUMAN	Increases Expression	[5]
BET1-like protein (BET1L)	OT5QVYBZ	BET1L_HUMAN	Increases Expression	[5]
Large ribosomal subunit protein bL35m (MRPL35)	OT85WBWJ	RM35_HUMAN	Decreases Expression	[5]
Denticleless protein homolog (DTL)	OTC29RYE	DTL_HUMAN	Decreases Expression	[5]
Ubiquinone biosynthesis O-methyltransferase, mitochondrial (COQ3)	OTSGT89T	COQ3_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13)	OT0UOKIT	NDUAD_HUMAN	Decreases Expression	[5]
Armadillo repeat-containing X-linked protein 1 (ARMCX1)	OTOGL58Z	ARMX1_HUMAN	Increases Expression	[5]
E3 ubiquitin-protein ligase MARCHF4 (MARCHF4)	OTK43VNA	MARH4_HUMAN	Decreases Expression	[5]
A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9)	OTV3Q0DS	ATS9_HUMAN	Decreases Expression	[5]
Kelch-like protein 13 (KLHL13)	OTUNG578	KLH13_HUMAN	Decreases Expression	[5]
7-dehydrocholesterol reductase (DHCR7)	OTLILBUI	DHCR7_HUMAN	Decreases Expression	[5]
Voltage-dependent calcium channel gamma-4 subunit (CACNG4)	OTE70DMK	CCG4_HUMAN	Decreases Expression	[5]
Mitochondrial dicarboxylate carrier (SLC25A10)	OTT8647H	DIC_HUMAN	Decreases Expression	[5]
Mitochondrial fission process protein 1 (MTFP1)	OT3L6F7U	MTFP1_HUMAN	Decreases Expression	[5]
Translocation protein SEC63 homolog (SEC63)	OT1ICPMK	SEC63_HUMAN	Increases Expression	[5]
Solute carrier family 2, facilitated glucose transporter member 6 (SLC2A6)	OTVUZCLG	GTR6_HUMAN	Decreases Expression	[5]
Armadillo repeat-containing X-linked protein 3 (ARMCX3)	OTMG7RWW	ARMX3_HUMAN	Increases Expression	[5]
Transcription factor COE1 (EBF1)	OTZ61YYH	COE1_HUMAN	Decreases Expression	[5]
Contactin-associated protein-like 2 (CNTNAP2)	OT48T2ZP	CNTP2_HUMAN	Increases Expression	[5]
NADH dehydrogenase 1 alpha subcomplex subunit 12 (NDUFA12)	OTCD6I5M	NDUAC_HUMAN	Decreases Expression	[5]
Transgelin-3 (TAGLN3)	OTJBP3VJ	TAGL3_HUMAN	Decreases Expression	[5]
GTP:AMP phosphotransferase AK3, mitochondrial (AK3)	OTM59ZGG	KAD3_HUMAN	Decreases Expression	[5]
Regulating synaptic membrane exocytosis protein 3 (RIMS3)	OTHN3H0A	RIMS3_HUMAN	Increases Expression	[5]
Lysosome-associated membrane glycoprotein 5 (LAMP5)	OTC672RM	LAMP5_HUMAN	Decreases Expression	[5]
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13)	OTTZVSK6	S2513_HUMAN	Decreases Expression	[5]
Drebrin-like protein (DBNL)	OTT2OQOV	DBNL_HUMAN	Decreases Expression	[5]
Cell cycle progression protein 1 (CCPG1)	OT0IHDKL	CCPG1_HUMAN	Increases Expression	[5]
Protein timeless homolog (TIMELESS)	OTD8DCBJ	TIM_HUMAN	Decreases Expression	[5]
Exonuclease 1 (EXO1)	OTI87RS5	EXO1_HUMAN	Decreases Expression	[5]
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C)	OTEU05TX	PPR3C_HUMAN	Decreases Expression	[5]
Histone deacetylase 5 (HDAC5)	OTWG387P	HDAC5_HUMAN	Increases Expression	[5]
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (PIN4)	OT403QC1	PIN4_HUMAN	Decreases Expression	[5]
Transcription factor 19 (TCF19)	OT7NKLF9	TCF19_HUMAN	Decreases Expression	[5]
DNA replication complex GINS protein PSF2 (GINS2)	OT974IYI	PSF2_HUMAN	Decreases Expression	[5]
Carbonic anhydrase 5B, mitochondrial (CA5B)	OTCIMJ8E	CAH5B_HUMAN	Increases Expression	[5]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5)	OT03QCLM	ATF5_HUMAN	Increases Expression	[5]
GDP-fucose protein O-fucosyltransferase 2 (POFUT2)	OT1MNJFZ	OFUT2_HUMAN	Increases Expression	[5]
Netrin-G1 (NTNG1)	OTF48IID	NTNG1_HUMAN	Increases Expression	[5]
Small ribosomal subunit protein bS1m (MRPS28)	OT8CLJ6M	RT28_HUMAN	Decreases Expression	[5]
Calcium-regulated heat-stable protein 1 (CARHSP1)	OTAUG6Y9	CHSP1_HUMAN	Decreases Expression	[5]
Conserved oligomeric Golgi complex subunit 6 (COG6)	OTDLQITC	COG6_HUMAN	Increases Expression	[5]
DNA-directed RNA polymerase III subunit RPC10 (POLR3K)	OTZCSF6A	RPC10_HUMAN	Decreases Expression	[5]
Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1)	OTYK9JU6	CIA30_HUMAN	Decreases Expression	[5]
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2)	OTURGRA8	MSRB2_HUMAN	Increases Expression	[5]
Dystrobrevin alpha (DTNA)	OTVBIRH2	DTNA_HUMAN	Decreases Expression	[5]
Hypoxia up-regulated protein 1 (HYOU1)	OTBGBSOV	HYOU1_HUMAN	Increases Expression	[5]
Sorting and assembly machinery component 50 homolog (SAMM50)	OTRYFYIU	SAM50_HUMAN	Increases Expression	[5]
DNA-directed RNA polymerase III subunit RPC8 (POLR3H)	OT7GM7MX	RPC8_HUMAN	Decreases Expression	[5]
Peptidyl-prolyl cis-trans isomerase A-like 4A (PPIAL4A)	OTJTMY5T	PAL4A_HUMAN	Decreases Expression	[5]
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22)	OTJMHX1V	TIM22_HUMAN	Decreases Expression	[5]
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1)	OTJQL0I3	HEY1_HUMAN	Decreases Expression	[5]
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9)	OTK7PDNN	TIM9_HUMAN	Increases Expression	[5]
Signal recognition particle receptor subunit beta (SRPRB)	OTUUFHQS	SRPRB_HUMAN	Increases Expression	[5]
Fatty acid desaturase 3 (FADS3)	OT9RVXGE	FADS3_HUMAN	Increases Expression	[5]
Sorting nexin-10 (SNX10)	OT05B7BT	SNX10_HUMAN	Decreases Expression	[5]
Beta-1,3-N-acetylglucosaminyltransferase radical fringe (RFNG)	OTWAN10O	RFNG_HUMAN	Increases Expression	[5]
Dolichyl-phosphate beta-glucosyltransferase (ALG5)	OT006CEI	ALG5_HUMAN	Increases Expression	[5]
Small ribosomal subunit protein mS40 (MRPS18B)	OT1K9PFX	RT18B_HUMAN	Increases Expression	[5]
Coatomer subunit gamma-1 (COPG1)	OT2NLQVH	COPG1_HUMAN	Increases Expression	[5]
Glucocorticoid modulatory element-binding protein 1 (GMEB1)	OT4F8RFH	GMEB1_HUMAN	Decreases Expression	[5]
LHFPL tetraspan subfamily member 6 protein (LHFPL6)	OTY6LHJY	LHPL6_HUMAN	Increases Expression	[5]
Mitochondrial carrier homolog 2 (MTCH2)	OTV3E4GU	MTCH2_HUMAN	Decreases Expression	[5]
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9)	OTO3WI7S	NDUB9_HUMAN	Decreases Expression	[5]
Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11)	OT0N3WL9	COX11_HUMAN	Increases Expression	[5]
Stress-associated endoplasmic reticulum protein 1 (SERP1)	OT60XXUP	SERP1_HUMAN	Increases Expression	[5]
Ret finger protein-like 4A (RFPL4A)	OTROUM09	RFPLA_HUMAN	Increases Expression	[6]
Interferon-related developmental regulator 1 (IFRD1)	OT4SQMLQ	IFRD1_HUMAN	Increases Expression	[6]
CCN family member 1 (CCN1)	OTKJBEMD	CCN1_HUMAN	Increases Expression	[6]
Laminin subunit alpha-5 (LAMA5)	OTIIXE4M	LAMA5_HUMAN	Decreases Expression	[6]
Beta-1,4-galactosyltransferase 5 (B4GALT5)	OTHMZY12	B4GT5_HUMAN	Increases Expression	[6]
Mothers against decapentaplegic homolog 6 (SMAD6)	OTUZZWUD	SMAD6_HUMAN	Decreases Expression	[6]
Galanin receptor type 2 (GALR2)	OTNJBJC1	GALR2_HUMAN	Increases Expression	[6]
Acyl-CoA (FADS1)	OTUYOYHX	FADS1_HUMAN	Increases Expression	[6]
Integral membrane protein GPR137B (GPR137B)	OT1CINQQ	G137B_HUMAN	Decreases Expression	[6]
Forkhead box protein D2 (FOXD2)	OTAF63YV	FOXD2_HUMAN	Decreases Expression	[6]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)	OTL9I7LO	GA45B_HUMAN	Increases Expression	[6]
Lathosterol oxidase (SC5D)	OT41KMW4	SC5D_HUMAN	Increases Expression	[6]
Retinal dehydrogenase 2 (ALDH1A2)	OTJB560Z	AL1A2_HUMAN	Decreases Expression	[6]
Serine protease 23 (PRSS23)	OT6DQAM1	PRS23_HUMAN	Increases Expression	[6]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G)	OT8V1J4M	GA45G_HUMAN	Increases Expression	[6]
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)	OTDLEXPN	PAPS2_HUMAN	Decreases Expression	[6]
Lymphocyte antigen 6 complex locus protein G6d (LY6G6D)	OTG75QOC	LY66D_HUMAN	Decreases Expression	[6]
Ubiquitin-like protein ISG15 (ISG15)	OT53QQ7N	ISG15_HUMAN	Increases Expression	[6]
Alkaline phosphatase, placental type (ALPP)	OTZU4G9W	PPB1_HUMAN	Increases Expression	[6]
Transcription factor Jun (JUN)	OTCYBO6X	JUN_HUMAN	Increases Expression	[6]
Alpha-galactosidase A (GLA)	OTBSR6DT	AGAL_HUMAN	Increases Expression	[6]
Lipoprotein lipase (LPL)	OTTW0267	LIPL_HUMAN	Increases Expression	[6]
Asialoglycoprotein receptor 1 (ASGR1)	OTS99MJO	ASGR1_HUMAN	Increases Expression	[6]
Keratin, type I cytoskeletal 19 (KRT19)	OTDGDQ75	K1C19_HUMAN	Decreases Expression	[6]
U1 small nuclear ribonucleoprotein A (SNRPA)	OT02TSQT	SNRPA_HUMAN	Decreases Expression	[6]
Homeobox protein Hox-B5 (HOXB5)	OTU74TB8	HXB5_HUMAN	Decreases Expression	[6]
Gamma-enolase (ENO2)	OTRODL0T	ENOG_HUMAN	Increases Expression	[6]
Retinol-binding protein 1 (RBP1)	OTRP1MFC	RET1_HUMAN	Decreases Expression	[6]
Heme oxygenase 1 (HMOX1)	OTC1W6UX	HMOX1_HUMAN	Increases Expression	[6]
Calcitonin gene-related peptide 2 (CALCB)	OTNVY7WY	CALCB_HUMAN	Increases Expression	[6]
COUP transcription factor 1 (NR2F1)	OTGWZWYL	COT1_HUMAN	Decreases Expression	[6]
Ras-related protein Ral-B (RALB)	OTFH203X	RALB_HUMAN	Decreases Expression	[6]
Cytochrome b-245 light chain (CYBA)	OT16N9ZO	CY24A_HUMAN	Decreases Expression	[6]
CD44 antigen (CD44)	OT9TTJ41	CD44_HUMAN	Increases Expression	[6]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2)	OTGVC9MY	PLCG2_HUMAN	Decreases Expression	[6]
Transcription factor JunD (JUND)	OTNKACJD	JUND_HUMAN	Increases Expression	[6]
Protachykinin-1 (TAC1)	OTM842YW	TKN1_HUMAN	Increases Expression	[6]
Collagen alpha-1(V) chain (COL5A1)	OT24078H	CO5A1_HUMAN	Decreases Expression	[6]
Insulin-like growth factor-binding protein 5 (IGFBP5)	OTRE5V0C	IBP5_HUMAN	Decreases Expression	[6]
Dual specificity protein phosphatase 1 (DUSP1)	OTN6BR75	DUS1_HUMAN	Increases Expression	[6]
Homeobox protein Hox-A10 (HOXA10)	OTB6GQ09	HXA10_HUMAN	Decreases Expression	[6]
Homeobox protein Hox-A13 (HOXA13)	OTTRI3KI	HXA13_HUMAN	Decreases Expression	[6]
Homeobox protein Hox-C8 (HOXC8)	OTJUYU8J	HXC8_HUMAN	Decreases Expression	[6]
Homeobox protein Hox-C9 (HOXC9)	OT60K4M0	HXC9_HUMAN	Decreases Expression	[6]
Homeobox protein Hox-C13 (HOXC13)	OT52AVNA	HXC13_HUMAN	Decreases Expression	[6]
ETS-related transcription factor Elf-1 (ELF1)	OTV5LKIA	ELF1_HUMAN	Increases Expression	[6]
Cystathionine gamma-lyase (CTH)	OTC90LA0	CGL_HUMAN	Increases Expression	[6]
CD70 antigen (CD70)	OTHB2AL1	CD70_HUMAN	Increases Expression	[6]
Fibrillin-2 (FBN2)	OT3KYJQL	FBN2_HUMAN	Increases Expression	[6]
Metalloproteinase inhibitor 3 (TIMP3)	OTDGQAD1	TIMP3_HUMAN	Increases Expression	[6]
Transcription factor SOX-18 (SOX18)	OTPUMHWA	SOX18_HUMAN	Decreases Expression	[6]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[6]
Pre-B-cell leukemia transcription factor 3 (PBX3)	OT8WMVM4	PBX3_HUMAN	Decreases Expression	[6]
Regulator of G-protein signaling 2 (RGS2)	OT0FSRW7	RGS2_HUMAN	Increases Expression	[6]
Beta-crystallin B2 (CRYBB2)	OTL0Z8E6	CRBB2_HUMAN	Increases Expression	[6]
LIM/homeobox protein Lhx2 (LHX2)	OTK61NP8	LHX2_HUMAN	Decreases Expression	[6]
Calcipressin-1 (RCAN1)	OT1MVXC7	RCAN1_HUMAN	Increases Expression	[6]
Myomesin-2 (MYOM2)	OTD2UOXW	MYOM2_HUMAN	Decreases Expression	[6]
Growth arrest-specific protein 1 (GAS1)	OTKJXG52	GAS1_HUMAN	Increases Expression	[6]
Proteinase-activated receptor 2 (F2RL1)	OTMRMJ8N	PAR2_HUMAN	Increases Expression	[6]
Ras-related protein Rab-38 (RAB38)	OTU0NZU0	RAB38_HUMAN	Decreases Expression	[6]
Cortexin-1 (CTXN1)	OTQQ9UBY	CTXN1_HUMAN	Decreases Expression	[6]
Protein S100-A10 (S100A10)	OTI71243	S10AA_HUMAN	Decreases Expression	[6]
Signal peptidase complex subunit 3 (SPCS3)	OTAPFSUQ	SPCS3_HUMAN	Increases Expression	[6]
ADP-ribosylation factor 3 (ARF3)	OTYYQX85	ARF3_HUMAN	Decreases Expression	[6]
Osteocrin (OSTN)	OTL4A57N	OSTN_HUMAN	Increases Expression	[6]
Actin, aortic smooth muscle (ACTA2)	OTEDLG8E	ACTA_HUMAN	Decreases Expression	[6]
Iroquois-class homeodomain protein IRX-3 (IRX3)	OTLJ48FG	IRX3_HUMAN	Decreases Expression	[6]
Forkhead box protein O4 (FOXO4)	OT90X9LN	FOXO4_HUMAN	Decreases Expression	[6]
DNA-binding protein inhibitor ID-3 (ID3)	OTUULW5Z	ID3_HUMAN	Decreases Expression	[6]
Transforming growth factor beta receptor type 3 (TGFBR3)	OTQOOUC4	TGBR3_HUMAN	Decreases Expression	[6]
Activin receptor type-1 (ACVR1)	OT4JATFE	ACVR1_HUMAN	Increases Expression	[6]
Cingulin-like protein 1 (CGNL1)	OTRE9DGT	CGNL1_HUMAN	Decreases Expression	[6]
Nucleoside diphosphate kinase 3 (NME3)	OT0CA0GF	NDK3_HUMAN	Decreases Expression	[6]
Syntaxin-3 (STX3)	OT4CIWLJ	STX3_HUMAN	Increases Expression	[6]
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)	OTHBQVD5	4EBP1_HUMAN	Increases Expression	[6]
Ras-related protein Rab-31 (RAB31)	OTMLXQZ0	RAB31_HUMAN	Decreases Expression	[6]
Cold-inducible RNA-binding protein (CIRBP)	OTXWTPBL	CIRBP_HUMAN	Increases Expression	[6]
Flotillin-2 (FLOT2)	OTZ0QR5L	FLOT2_HUMAN	Decreases Expression	[6]
Transcription factor HES-1 (HES1)	OT8P19W2	HES1_HUMAN	Decreases Expression	[6]
Phosphatidate phosphatase LPIN1 (LPIN1)	OTQ75KF2	LPIN1_HUMAN	Increases Expression	[6]
CCAAT/enhancer-binding protein epsilon (CEBPE)	OTKZA25M	CEBPE_HUMAN	Increases Expression	[6]
Alpha-internexin (INA)	OT1D33T4	AINX_HUMAN	Increases Expression	[6]
Nuclear factor interleukin-3-regulated protein (NFIL3)	OTQH9HM3	NFIL3_HUMAN	Increases Expression	[6]
Cytochrome P450 1B1 (CYP1B1)	OTYXFLSD	CP1B1_HUMAN	Increases Expression	[6]
Dual specificity protein phosphatase 5 (DUSP5)	OTH96RA7	DUS5_HUMAN	Decreases Expression	[6]
Histone H2A type 2-C (H2AC20)	OTEIVLM1	H2A2C_HUMAN	Increases Expression	[6]
SKI/DACH domain-containing protein 1 (SKIDA1)	OTI3EOET	SKDA1_HUMAN	Decreases Expression	[6]
MHC class I polypeptide-related sequence B (MICB)	OTS2DVDW	MICB_HUMAN	Increases Expression	[6]
Keratin-associated protein 21-2 (KRTAP21-2)	OT1JVP79	KR212_HUMAN	Increases Expression	[6]
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 (ITPRIPL2)	OTSSP13W	IPIL2_HUMAN	Decreases Expression	[6]
Membrane protein FAM174B (FAM174B)	OT1SCOTY	F174B_HUMAN	Increases Expression	[6]
Angiomotin (AMOT)	OTWHDG9B	AMOT_HUMAN	Decreases Expression	[6]
Protein LBH (LBH)	OT87AT1X	LBH_HUMAN	Increases Expression	[6]
Metaxin-3 (MTX3)	OTFYDBAT	MTX3_HUMAN	Increases Expression	[6]
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EARS2)	OTNCJKY7	SYEM_HUMAN	Decreases Expression	[6]
RRP12-like protein (RRP12)	OTQQAEH4	RRP12_HUMAN	Increases Expression	[6]
Uncharacterized protein C6orf141 (C6ORF141)	OTUS3SIQ	CF141_HUMAN	Increases Expression	[6]
Mitochondrial amidoxime-reducing component 1 (MTARC1)	OTNBE033	MARC1_HUMAN	Decreases Expression	[6]
Muscleblind-like protein 2 (MBNL2)	OTF7CF1F	MBNL2_HUMAN	Increases Expression	[6]
Protein sel-1 homolog 3 (SEL1L3)	OT10N6Z2	SE1L3_HUMAN	Increases Expression	[6]
Tetratricopeptide repeat protein 19, mitochondrial (TTC19)	OTQ0QH1P	TTC19_HUMAN	Increases Expression	[6]
Histone H2A type 2-A (H2AC18)	OTCE5JC7	H2A2A_HUMAN	Increases Expression	[6]
Endoplasmic reticulum aminopeptidase 2 (ERAP2)	OTEMENYF	ERAP2_HUMAN	Decreases Expression	[6]
Glucose 1,6-bisphosphate synthase (PGM2L1)	OTSBNRT5	PGM2L_HUMAN	Increases Expression	[6]
Prostate androgen-regulated mucin-like protein 1 (PARM1)	OTDNK7EX	PARM1_HUMAN	Increases Expression	[6]
Protein shisa-2 homolog (SHISA2)	OT4GMTML	SHSA2_HUMAN	Increases Expression	[6]
Dehydrogenase/reductase SDR family member 13 (DHRS13)	OT45VM0J	DHR13_HUMAN	Increases Expression	[6]
Serine/threonine-protein kinase TAO1 (TAOK1)	OTFFLV6Q	TAOK1_HUMAN	Increases Expression	[6]
Uncharacterized protein C11orf96 (C11ORF96)	OTEQU0V7	CK096_HUMAN	Increases Expression	[6]
Epoxide hydrolase 4 (EPHX4)	OTMLVHIH	EPHX4_HUMAN	Increases Expression	[6]
L-seryl-tRNA(Sec) kinase (PSTK)	OTA5UXAX	PSTK_HUMAN	Increases Expression	[6]
Cytochrome P450 4X1 (CYP4X1)	OTMTEUNE	CP4X1_HUMAN	Increases Expression	[6]
Reprimo-like protein (RPRML)	OTPOESFN	RPRML_HUMAN	Decreases Expression	[6]
Macoilin (MACO1)	OTT9W0BR	MACOI_HUMAN	Increases Expression	[6]
Centrosomal protein POC5 (POC5)	OTHD4FIH	POC5_HUMAN	Increases Expression	[6]
Testis-expressed protein 19 (TEX19)	OTY6MIZ9	TEX19_HUMAN	Increases Expression	[6]
Transmembrane protein C1orf162 (C1ORF162)	OT6TC9TZ	CA162_HUMAN	Increases Expression	[6]
Nuclear receptor coactivator 7 (NCOA7)	OT2CNBOG	NCOA7_HUMAN	Increases Expression	[6]
Solute carrier family 35 member G2 (SLC35G2)	OTFBVS0P	S35G2_HUMAN	Increases Expression	[6]
Serine/threonine-protein kinase BRSK1 (BRSK1)	OT6N35Q0	BRSK1_HUMAN	Increases Expression	[6]
Probable glutathione peroxidase 8 (GPX8)	OTTH80PN	GPX8_HUMAN	Increases Expression	[6]
Sodium-dependent phosphate transporter 1 (SLC20A1)	OTC3D894	S20A1_HUMAN	Increases Expression	[6]
Protein NDRG1 (NDRG1)	OTVO66BO	NDRG1_HUMAN	Increases Expression	[6]
Peroxidasin homolog (PXDN)	OTFGGM9R	PXDN_HUMAN	Increases Expression	[6]
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1)	OT1IK0KA	VPP1_HUMAN	Increases Expression	[6]
Repulsive guidance molecule A (RGMA)	OTZAMDO2	RGMA_HUMAN	Decreases Expression	[6]
TLC domain-containing protein 1 (TLCD1)	OTD2VADH	TLCD1_HUMAN	Increases Expression	[6]
THAP domain-containing protein 11 (THAP11)	OTEMWLZ0	THA11_HUMAN	Decreases Expression	[6]
Serine dehydratase-like (SDSL)	OTGZEAGJ	SDSL_HUMAN	Increases Expression	[6]
DDRGK domain-containing protein 1 (DDRGK1)	OT3KCK0U	DDRGK_HUMAN	Increases Expression	[6]
CDK5 regulatory subunit-associated protein 3 (CDK5RAP3)	OTC0Q2QS	CK5P3_HUMAN	Increases Expression	[6]
RING finger protein 145 (RNF145)	OTBCTG4A	RN145_HUMAN	Increases Expression	[6]
Sodium-coupled neutral amino acid symporter 2 (SLC38A2)	OTALABSK	S38A2_HUMAN	Increases Expression	[6]
Germ cell nuclear acidic protein (GCNA)	OTIU3F9Y	GCNA_HUMAN	Increases Expression	[6]
Tribbles homolog 1 (TRIB1)	OTPEO17G	TRIB1_HUMAN	Increases Expression	[6]
Cysteine/serine-rich nuclear protein 1 (CSRNP1)	OTDK1FPH	CSRN1_HUMAN	Increases Expression	[6]
Transmembrane protein 209 (TMEM209)	OTH9U9U1	TM209_HUMAN	Increases Expression	[6]
Proheparin-binding EGF-like growth factor (HBEGF)	OTLU00JS	HBEGF_HUMAN	Increases Expression	[6]
Sialidase-1 (NEU1)	OTH9BY8Y	NEUR1_HUMAN	Increases Expression	[6]
TSC22 domain family protein 3 (TSC22D3)	OT03UM03	T22D3_HUMAN	Increases Expression	[6]
Protein C10 (C12ORF57)	OT7V1MLD	C10_HUMAN	Increases Expression	[6]
Selenoprotein S (SELENOS)	OTUEWIU9	SELS_HUMAN	Increases Expression	[6]
Mesoderm posterior protein 1 (MESP1)	OTY5QDBN	MESP1_HUMAN	Increases Expression	[6]
Transmembrane protein 79 (TMEM79)	OTEC6EFU	TMM79_HUMAN	Increases Expression	[6]
Synaptotagmin-11 (SYT11)	OTLRTZEI	SYT11_HUMAN	Increases Expression	[6]
MAPK regulated corepressor interacting protein 2 (MCRIP2)	OTAJR36W	MCRI2_HUMAN	Decreases Expression	[6]
EMILIN-2 (EMILIN2)	OTOYK5A8	EMIL2_HUMAN	Increases Expression	[6]
Protein BEX2 (BEX2)	OT4G5SIC	BEX2_HUMAN	Increases Expression	[6]
Cell adhesion molecule 1 (CADM1)	OTRWG9QS	CADM1_HUMAN	Decreases Expression	[6]
Tripartite motif-containing protein 2 (TRIM2)	OT0V1YVC	TRIM2_HUMAN	Increases Expression	[6]
Potassium channel subfamily K member 12 (KCNK12)	OTFP82TK	KCNKC_HUMAN	Increases Expression	[6]
Protein S100-A14 (S100A14)	OTVFJJ91	S10AE_HUMAN	Increases Expression	[6]
Serine--tRNA ligase, mitochondrial (SARS2)	OTU4T99W	SYSM_HUMAN	Increases Expression	[6]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A)	OT5V52LN	TNR12_HUMAN	Increases Expression	[6]
Cartilage acidic protein 1 (CRTAC1)	OT4PGEVE	CRAC1_HUMAN	Increases Expression	[6]
Cell death regulator Aven (AVEN)	OTGIN5YK	AVEN_HUMAN	Increases Expression	[6]
NEDD4 family-interacting protein 2 (NDFIP2)	OT34DCAP	NFIP2_HUMAN	Increases Expression	[6]
Transmembrane protein 160 (TMEM160)	OTWVIV7I	TM160_HUMAN	Decreases Expression	[6]
Ankyrin repeat domain-containing protein 10 (ANKRD10)	OTIZ2VK8	ANR10_HUMAN	Increases Expression	[6]
Protein FAM13B (FAM13B)	OTNQTYSM	FA13B_HUMAN	Increases Expression	[6]
Cingulin (CGN)	OTBCQ8AQ	CING_HUMAN	Decreases Expression	[6]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (GNG12)	OTOGF42G	GBG12_HUMAN	Decreases Expression	[6]
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D)	OTOSRDJT	TR10D_HUMAN	Increases Expression	[6]
Nuclear RNA export factor 1 (NXF1)	OTEFHXG6	NXF1_HUMAN	Increases Expression	[6]
NADH-cytochrome b5 reductase 1 (CYB5R1)	OTMDHMLA	NB5R1_HUMAN	Increases Expression	[6]
SERTA domain-containing protein 1 (SERTAD1)	OTBHKZQP	SRTD1_HUMAN	Increases Expression	[6]
Prenylated Rab acceptor protein 1 (RABAC1)	OTGB32NG	PRAF1_HUMAN	Increases Expression	[6]
Beta-citrylglutamate synthase B (RIMKLB)	OT27A1MS	RIMKB_HUMAN	Increases Expression	[6]
Protein PHTF1 (PHTF1)	OTYCZ84A	PHTF1_HUMAN	Increases Expression	[6]
Cystine/glutamate transporter (SLC7A11)	OTKJ6PXW	XCT_HUMAN	Increases Expression	[6]
Ribosome maturation protein SBDS (SBDS)	OTHDCCIB	SBDS_HUMAN	Increases Expression	[6]
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2)	OTJBDX0Y	VPP2_HUMAN	Increases Expression	[6]
Retinoic acid-induced protein 2 (RAI2)	OTR8LX4J	RAI2_HUMAN	Decreases Expression	[6]
Dynamin-1-like protein (DNM1L)	OTXK1Q1G	DNM1L_HUMAN	Increases Expression	[14]
Transmembrane protease serine 2 (TMPRSS2)	OTN44YQ5	TMPS2_HUMAN	Decreases Expression	[15]
Calumenin (CALU)	OTSYQN71	CALU_HUMAN	Decreases Expression	[7]
Dynamin-like 120 kDa protein, mitochondrial (OPA1)	OTJGNWPW	OPA1_HUMAN	Increases Expression	[14]
Nuclear protein 1 (NUPR1)	OT4FU8C0	NUPR1_HUMAN	Increases Expression	[16]
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP)	OTRNDZXB	HNRPQ_HUMAN	Affects Localization	[17]
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3)	OTT00T7Q	PLOD3_HUMAN	Decreases Expression	[7]
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1)	OTY9R6FZ	ERN1_HUMAN	Increases Expression	[18]
Nuclear receptor subfamily 1 group I member 2 (NR1I2)	OTC5U0N5	NR1I2_HUMAN	Decreases Expression	[19]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)	OTYG179K	PR15A_HUMAN	Increases Expression	[20]
Ribosomal L1 domain-containing protein 1 (RSL1D1)	OT3CL4R3	RL1D1_HUMAN	Affects Expression	[21]
Mitofusin-2 (MFN2)	OTPYN8A3	MFN2_HUMAN	Increases Expression	[14]
Alpha-1-antitrypsin (SERPINA1)	OTACYW9J	A1AT_HUMAN	Increases Expression	[7]
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[21]
Tumor necrosis factor (TNF)	OT4IE164	TNFA_HUMAN	Increases Expression	[22]
Interleukin-1 beta (IL1B)	OT0DWXXB	IL1B_HUMAN	Increases Expression	[23]
Keratin, type II cytoskeletal 6A (KRT6A)	OT392M5T	K2C6A_HUMAN	Decreases Expression	[7]
Apolipoprotein C-III (APOC3)	OTW3520C	APOC3_HUMAN	Decreases Expression	[24]
Apolipoprotein B-100 (APOB)	OTH0UOCZ	APOB_HUMAN	Decreases Expression	[24]
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1)	OTTO6ZP4	AT1B1_HUMAN	Increases Expression	[25]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1)	OTM0GDTP	IF2A_HUMAN	Increases Expression	[26]
Interleukin-6 (IL6)	OTUOSCCU	IL6_HUMAN	Increases Expression	[22]
Keratin, type II cytoskeletal 8 (KRT8)	OTTM4X11	K2C8_HUMAN	Decreases Expression	[7]
Prostate-specific antigen (KLK3)	OTFGSBFJ	KLK3_HUMAN	Decreases Expression	[15]
Complement decay-accelerating factor (CD55)	OTZ3HWTO	DAF_HUMAN	Increases Expression	[21]
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Decreases Expression	[27]
5-hydroxytryptamine receptor 1A (HTR1A)	OT38K9MK	5HT1A_HUMAN	Increases Activity	[28]
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1)	OTIRPN6B	ROA1_HUMAN	Affects Localization	[29]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Increases Expression	[22]
Endoplasmic reticulum chaperone BiP (HSPA5)	OTFUIRAO	BIP_HUMAN	Increases Expression	[8]
C-C motif chemokine 2 (CCL2)	OTAD2HEL	CCL2_HUMAN	Increases Expression	[22]
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2)	OTPGAU0U	AT2A2_HUMAN	Increases Expression	[30]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3)	OTC1UOHP	ATF3_HUMAN	Increases Expression	[31]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4)	OTRFV19J	ATF4_HUMAN	Increases Expression	[32]
Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6)	OTAFHAVI	ATF6A_HUMAN	Increases Expression	[18]
Kallikrein-2 (KLK2)	OT9RE37R	KLK2_HUMAN	Decreases Expression	[15]
Protein EVI2A (EVI2A)	OTR8RUXQ	EVI2A_HUMAN	Increases Expression	[21]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Decreases Expression	[31]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Increases Expression	[31]
Tumor necrosis factor receptor superfamily member 6 (FAS)	OTP9XG86	TNR6_HUMAN	Increases Expression	[25]
Mitogen-activated protein kinase 3 (MAPK3)	OTCYKGKO	MK03_HUMAN	Increases Phosphorylation	[10]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Increases Phosphorylation	[10]
Caspase-1 (CASP1)	OTZ3YQFU	CASP1_HUMAN	Increases Expression	[23]
Protein disulfide-isomerase A3 (PDIA3)	OTHPQ0Q3	PDIA3_HUMAN	Increases Expression	[33]
Pro-adrenomedullin (ADM)	OT7T0TA4	ADML_HUMAN	Decreases Expression	[34]
DNA damage-inducible transcript 3 protein (DDIT3)	OTI8YKKE	DDIT3_HUMAN	Increases Expression	[35]
Breast cancer type 1 susceptibility protein (BRCA1)	OT5BN6VH	BRCA1_HUMAN	Increases Expression	[36]
Hepatocyte nuclear factor 4-alpha (HNF4A)	OTY1TOAB	HNF4A_HUMAN	Decreases Expression	[19]
Tumor necrosis factor ligand superfamily member 9 (TNFSF9)	OTV9L89D	TNFL9_HUMAN	Increases Expression	[21]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Increases Activity	[37]
Caspase-2 (CASP2)	OTUDYSPP	CASP2_HUMAN	Increases Activity	[38]
Large ribosomal subunit protein uL15 (RPL27A)	OTQQHPL0	RL27A_HUMAN	Affects Expression	[21]
Protein ERGIC-53 (LMAN1)	OTYHKDEO	LMAN1_HUMAN	Increases Expression	[39]
Breast cancer type 2 susceptibility protein (BRCA2)	OTF1XSV1	BRCA2_HUMAN	Increases Expression	[36]
Microsomal triglyceride transfer protein large subunit (MTTP)	OTNUVSDT	MTP_HUMAN	Decreases Expression	[24]
Caspase-7 (CASP7)	OTAPJ040	CASP7_HUMAN	Increases Activity	[37]
Caspase-9 (CASP9)	OTD4RFFG	CASP9_HUMAN	Increases Activity	[38]
Gem-associated protein 4 (GEMIN4)	OTX7402E	GEMI4_HUMAN	Decreases Expression	[21]
Gasdermin-D (GSDMD)	OTH39BKI	GSDMD_HUMAN	Increases Expression	[23]
Inhibin beta E chain (INHBE)	OTOI2NYG	INHBE_HUMAN	Increases Expression	[40]
Lysozyme C (LYZ)	OTD7H0G6	LYSC_HUMAN	Increases Secretion	[41]
Neutrophil gelatinase-associated lipocalin (LCN2)	OTSB42BR	NGAL_HUMAN	Increases Expression	[42]
Protein SET (SET)	OTGYYQJO	SET_HUMAN	Decreases Expression	[7]
Early activation antigen CD69 (CD69)	OTGJHSVP	CD69_HUMAN	Increases Expression	[21]
Apoptosis regulator BAX (BAX)	OTAW0V4V	BAX_HUMAN	Increases Activity	[43]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)	OT2YYI1A	MCL1_HUMAN	Increases Expression	[44]
Protein phosphatase 3 catalytic subunit alpha (PPP3CA)	OT58PUEN	PP2BA_HUMAN	Increases Expression	[18]
DnaJ homolog subfamily C member 3 (DNAJC3)	OT7ROIJF	DNJC3_HUMAN	Increases Expression	[20]
Eukaryotic translation initiation factor 3 subunit I (EIF3I)	OTE07WND	EIF3I_HUMAN	Decreases Expression	[7]
Baculoviral IAP repeat-containing protein 3 (BIRC3)	OT3E95KB	BIRC3_HUMAN	Increases Expression	[10]
Nascent polypeptide-associated complex subunit alpha (NACA)	OTLP1KR3	NACA_HUMAN	Decreases Expression	[7]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)	OTXEE550	APR_HUMAN	Increases Expression	[45]
Exosome complex component RRP4 (EXOSC2)	OTN6NVKL	EXOS2_HUMAN	Decreases Expression	[21]
Interleukin-18 (IL18)	OTBB2A8O	IL18_HUMAN	Increases Expression	[23]
Kelch-like ECH-associated protein 1 (KEAP1)	OTFHOD0C	KEAP1_HUMAN	Increases Expression	[46]
Reticulocalbin-2 (RCN2)	OTIU8JWD	RCN2_HUMAN	Decreases Expression	[7]
Nucleolar and coiled-body phosphoprotein 1 (NOLC1)	OTKDZU0D	NOLC1_HUMAN	Decreases Expression	[21]
Exosome complex component RRP42 (EXOSC7)	OTCGRKNK	EXOS7_HUMAN	Affects Expression	[21]
Rho-related GTP-binding protein RhoH (RHOH)	OT1J9SEB	RHOH_HUMAN	Decreases Expression	[21]
Cyclin-G2 (CCNG2)	OTII38K2	CCNG2_HUMAN	Increases Expression	[31]
Transcriptional protein SWT1 (SWT1)	OTY4AFM1	SWT1_HUMAN	Decreases Expression	[25]
Myomegalin (PDE4DIP)	OTS15WNF	MYOME_HUMAN	Increases Expression	[21]
Inactive caspase-12 (CASP12)	OTY2W6FG	CASPC_HUMAN	Increases Activity	[26]
Mitofusin-1 (MFN1)	OTCBXQZF	MFN1_HUMAN	Increases Expression	[14]
DnaJ homolog subfamily C member 10 (DNAJC10)	OTD2EG0R	DJC10_HUMAN	Increases Expression	[33]
Transmembrane protein 87A (TMEM87A)	OT8ATDVX	TM87A_HUMAN	Increases Expression	[25]
Programmed cell death 6-interacting protein (PDCD6IP)	OTS8T6A7	PDC6I_HUMAN	Increases Expression	[7]
Sec1 family domain-containing protein 1 (SCFD1)	OTN4T7JI	SCFD1_HUMAN	Decreases Expression	[7]
CREB-binding protein (CREBBP)	OTPA4QGM	CBP_HUMAN	Increases Expression	[21]
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1)	OT2JHIHM	CR3L1_HUMAN	Increases Activity	[47]
ERO1-like protein alpha (ERO1A)	OTVKOQWM	ERO1A_HUMAN	Increases Expression	[48]
DnaJ homolog subfamily C member 1 (DNAJC1)	OTCKFOZ0	DNJC1_HUMAN	Affects Expression	[21]
Bcl-2-modifying factor (BMF)	OT90NSLI	BMF_HUMAN	Decreases Expression	[25]
NACHT, LRR and PYD domains-containing protein 3 (NLRP3)	OTZM6MHU	NLRP3_HUMAN	Increases Expression	[23]
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A)	OTVFRL8G	TI17A_HUMAN	Increases Expression	[49]
Copine-1 (CPNE1)	OTH5YKSL	CPNE1_HUMAN	Decreases Expression	[7]
COP9 signalosome complex subunit 4 (COPS4)	OTNK2KS1	CSN4_HUMAN	Decreases Expression	[7]
Transcription regulator protein BACH2 (BACH2)	OT17GS18	BACH2_HUMAN	Increases Expression	[21]
Fibroblast growth factor 21 (FGF21)	OT3RXVRD	FGF21_HUMAN	Increases Expression	[50]
Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3)	OT0DZGY4	E2AK3_HUMAN	Increases Expression	[18]
DnaJ homolog subfamily B member 9 (DNAJB9)	OT38EQT6	DNJB9_HUMAN	Increases Expression	[20]
Apoptosis-associated speck-like protein containing a CARD (PYCARD)	OT67RON3	ASC_HUMAN	Increases Expression	[23]
Lactosylceramide alpha-2,3-sialyltransferase (ST3GAL5)	OT27CCUF	SIAT9_HUMAN	Decreases Expression	[25]
Mitochondrial fission 1 protein (FIS1)	OT2HL10J	FIS1_HUMAN	Increases Expression	[14]
Angiopoietin-related protein 3 (ANGPTL3)	OTCD5Z9W	ANGL3_HUMAN	Decreases Expression	[24]
Eukaryotic translation initiation factor 5A-1 (EIF5A)	OTQ8DJX5	IF5A1_HUMAN	Affects Response To Substance	[51]

Indication(s) of Prazosin

Disease Entry	ICD 11	Status	REF
Benign prostatic hyperplasia	GA90	Approved	[2]
Congestive heart failure	BD10	Approved	[2]
Hypertension	BA00-BA04	Approved	[2]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[3]

Prazosin Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Adrenergic receptor Alpha-1 (ADRA1)	TTG28O6	NOUNIPROTAC	Antagonist	[52]

Prazosin Interacts with 3 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[53]
Breast cancer resistance protein (ABCG2)	DTI7UX6	ABCG2_HUMAN	Substrate	[54]
Organic cation transporter 1 (SLC22A1)	DTT79CX	S22A1_HUMAN	Substrate	[55]

Prazosin Interacts with 1 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 1A1 (CYP1A1)	DE6OQ3W	CP1A1_HUMAN	Metabolism	[56]

References

• [1] Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [3] Prazosin to Prevent COVID-19 (PREVENT-COVID Trial) (PREVENT)
• [4] The genome-wide expression profile of Scrophularia ningpoensis-treated thapsigargin-stimulated U-87MG cells. Neurotoxicology. 2009 May;30(3):368-76.
• [5] Endoplasmic reticulum stress impairs insulin signaling through mitochondrial damage in SH-SY5Y cells. Neurosignals. 2012;20(4):265-80.
• [6] Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides. J Biol Chem. 2018 Apr 13;293(15):5600-5612.
• [7] Proteomic signatures in thapsigargin-treated hepatoma cells. Chem Res Toxicol. 2011 Aug 15;24(8):1215-22. doi: 10.1021/tx200109y. Epub 2011 Jul 1.
• [8] Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress. Invest Ophthalmol Vis Sci. 2002 Aug;43(8):2791-8.
• [9] Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis. Oncogene. 2010 Mar 4;29(9):1329-38. doi: 10.1038/onc.2009.425. Epub 2009 Nov 30.
• [10] Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J Biol Chem. 2004 Nov 19;279(47):49420-9. doi: 10.1074/jbc.M407700200. Epub 2004 Aug 31.
• [11] Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase. Bioorg Med Chem. 2010 Aug 1;18(15):5634-46.
• [12] Tissue transglutaminase serves as an inhibitor of apoptosis by cross-linking caspase 3 in thapsigargin-treated cells. Mol Cell Biol. 2006 Jan;26(2):569-79.
• [13] Cadmium induces transcription independently of intracellular calcium mobilization. PLoS One. 2011;6(6):e20542.
• [14] Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress. Br J Pharmacol. 2017 Dec;174(23):4409-4429. doi: 10.1111/bph.14045. Epub 2017 Nov 7.
• [15] Riluzole induces AR degradation via endoplasmic reticulum stress pathway in androgen-dependent and castration-resistant prostate cancer cells. Prostate. 2019 Feb;79(2):140-150. doi: 10.1002/pros.23719. Epub 2018 Oct 2.
• [16] Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells. J Biol Chem. 2010 Feb 26;285(9):6091-100. doi: 10.1074/jbc.M109.014092. Epub 2009 Dec 18.
• [17] Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments. Exp Cell Res. 2009 Apr 1;315(6):968-80. doi: 10.1016/j.yexcr.2009.01.012. Epub 2009 Feb 10.
• [18] Arsenic trioxide initiates ER stress responses, perturbs calcium signalling and promotes apoptosis in human lens epithelial cells. Exp Eye Res. 2007 Dec;85(6):825-35. doi: 10.1016/j.exer.2007.08.018. Epub 2007 Aug 29.
• [19] Suppression of the pregnane X receptor during endoplasmic reticulum stress is achieved by down-regulating hepatocyte nuclear factor-4 and up-regulating liver-enriched inhibitory protein. Toxicol Sci. 2015 Apr;144(2):382-92. doi: 10.1093/toxsci/kfv008. Epub 2015 Jan 22.
• [20] Protective effect against Parkinson's disease-related insults through the activation of XBP1. Brain Res. 2009 Feb 27;1257:16-24. doi: 10.1016/j.brainres.2008.11.104. Epub 2008 Dec 16.
• [21] DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells. Toxicol Lett. 2014 Jan 30;224(3):395-406. doi: 10.1016/j.toxlet.2013.11.005. Epub 2013 Nov 15.
• [22] Role of endoplasmic reticulum stress in acrolein-induced endothelial activation. Toxicol Appl Pharmacol. 2009 Jan 1;234(1):14-24. doi: 10.1016/j.taap.2008.09.019. Epub 2008 Oct 7.
• [23] Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells. Arch Toxicol. 2019 Apr;93(4):965-986. doi: 10.1007/s00204-019-02415-8. Epub 2019 Feb 22.
• [24] Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity. Cell Biol Toxicol. 2021 Apr;37(2):151-175. doi: 10.1007/s10565-020-09537-1. Epub 2020 Jun 14.
• [25] Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells. Arch Toxicol. 2021 May;95(5):1631-1645. doi: 10.1007/s00204-021-03014-2. Epub 2021 Mar 26.
• [26] The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro. Alcohol Clin Exp Res. 2014 Mar;38(3):683-93. doi: 10.1111/acer.12311. Epub 2013 Nov 13.
• [27] Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer. J Biol Chem. 2022 Feb;298(2):101492. doi: 10.1016/j.jbc.2021.101492. Epub 2021 Dec 13.
• [28] Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components. J Pharmacol Exp Ther. 2001 Jun;297(3):1025-35.
• [29] hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress. Biochem J. 2013 Jan 15;449(2):543-53. doi: 10.1042/BJ20120906.
• [30] Rosiglitazone induces the unfolded protein response, but has no significant effect on cell viability, in monocytic and vascular smooth muscle cells. Biochem Biophys Res Commun. 2010 Oct 1;400(4):689-95. doi: 10.1016/j.bbrc.2010.08.129. Epub 2010 Sep 9.
• [31] Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. J Pharmacol Exp Ther. 2007 Jun;321(3):830-8. doi: 10.1124/jpet.107.119412. Epub 2007 Mar 1.
• [32] Doxorubicin prevents endoplasmic reticulum stress-induced apoptosis. Biochem Biophys Res Commun. 2006 Jan 13;339(2):463-8. doi: 10.1016/j.bbrc.2005.11.040. Epub 2005 Nov 15.
• [33] Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57. Br J Cancer. 2007 Apr 10;96(7):1062-71. doi: 10.1038/sj.bjc.6603672. Epub 2007 Mar 13.
• [34] Role of calcium in lipopolysaccharide-induced calcitonin gene expression in human adipocytes. Innate Immun. 2011 Aug;17(4):403-13. doi: 10.1177/1753425910377100. Epub 2010 Aug 3.
• [35] Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells. Cancer Res. 2007 Feb 1;67(3):1262-9. doi: 10.1158/0008-5472.CAN-06-1794.
• [36] BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells. Br J Cancer. 2006 Feb 13;94(3):407-26. doi: 10.1038/sj.bjc.6602935.
• [37] Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep;36(3):592-601. doi: 10.1053/jhep.2002.35441.
• [38] Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signaling. Neuropharmacology. 2006 Apr;50(5):558-67. doi: 10.1016/j.neuropharm.2005.10.016. Epub 2006 Jan 4.
• [39] Heat shock induces preferential translation of ERGIC-53 and affects its recycling pathway. J Biol Chem. 2004 Oct 8;279(41):42535-44. doi: 10.1074/jbc.M401860200. Epub 2004 Jul 29.
• [40] Inhibin beta E is upregulated by drug-induced endoplasmic reticulum stress as a transcriptional target gene of ATF4. Toxicol Appl Pharmacol. 2012 Oct 15;264(2):300-4. doi: 10.1016/j.taap.2012.08.011. Epub 2012 Aug 23.
• [41] Regulation of antiprotease and antimicrobial protein secretion by airway submucosal gland serous cells. J Biol Chem. 2004 Sep 10;279(37):38854-60. doi: 10.1074/jbc.M407077200. Epub 2004 Jul 2.
• [42] Lipocalin 2, a new GADD153 target gene, as an apoptosis inducer of endoplasmic reticulum stress in lung cancer cells. Toxicol Appl Pharmacol. 2012 Sep 15;263(3):330-7. doi: 10.1016/j.taap.2012.07.005. Epub 2012 Jul 16.
• [43] Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation. J Membr Biol. 2010 Feb;233(1-3):105-18. doi: 10.1007/s00232-010-9230-0. Epub 2010 Feb 4.
• [44] Translational repression of MCL-1 couples stress-induced eIF2 alpha phosphorylation to mitochondrial apoptosis initiation. J Biol Chem. 2007 Aug 3;282(31):22551-62. doi: 10.1074/jbc.M702673200. Epub 2007 Jun 6.
• [45] Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours. Apoptosis. 2007 Mar;12(3):613-22. doi: 10.1007/s10495-006-0020-1.
• [46] High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities. Arch Toxicol. 2017 Mar;91(3):1367-1383. doi: 10.1007/s00204-016-1781-0. Epub 2016 Jun 29.
• [47] Transcriptional regulation of VEGFA by the endoplasmic reticulum stress transducer OASIS in ARPE-19 cells. PLoS One. 2013;8(1):e55155. doi: 10.1371/journal.pone.0055155. Epub 2013 Jan 30.
• [48] Inhibition of activity/expression, or genetic deletion, of ERO1 blunts arsenite geno- and cyto-toxicity. Food Chem Toxicol. 2022 Oct;168:113360. doi: 10.1016/j.fct.2022.113360. Epub 2022 Aug 12.
• [49] Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation. Cell Metab. 2013 Dec 3;18(6):908-19. doi: 10.1016/j.cmet.2013.11.006.
• [50] Fibroblast growth factor 21 is induced by endoplasmic reticulum stress. Biochimie. 2013 Apr;95(4):692-9. doi: 10.1016/j.biochi.2012.10.019. Epub 2012 Nov 2.
• [51] eIF5A promotes translation elongation, polysome disassembly and stress granule assembly. PLoS One. 2010 Apr 1;5(4):e9942. doi: 10.1371/journal.pone.0009942.
• [52] Adventitia removal does not modify the alphaID-adrenoceptors response in aorta during hypertension and ageing. Auton Autacoid Pharmacol. 2009 Jul;29(3):117-33.
• [53] Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10594-9.
• [54] P-glycoprotein and breast cancer resistance protein expression and function at the blood-brain barrier and blood-cerebrospinal fluid barrier (choroid plexus) in streptozotocin-induced diabetes in rats. Brain Res. 2011 Jan 25;1370:238-45.
• [55] Implications of genetic polymorphisms in drug transporters for pharmacotherapy. Cancer Lett. 2006 Mar 8;234(1):4-33.
• [56] Role of adrenoceptor-linked signaling pathways in the regulation of CYP1A1 gene expression. Biochem Pharmacol. 2005 Jan 15;69(2):277-87.