General Information of Disease (ID: DISDC067)

Disease Name Cardiac failure
Disease Class BD10-BD1Z: Heart failure
Disease Hierarchy
DIS01GPL: Grass pollen hypersensitivity
DISDC067: Cardiac failure
ICD Code
ICD-11
ICD-11: BD10-BD13
ICD-10
ICD-10: I50, I50.9
Expand ICD-11
'BD1Z
Expand ICD-10
'I50; 'I50.9
Disease Identifiers
MONDO ID
MONDO_0005252
MESH ID
D006333
UMLS CUI
C0018801
MedGen ID
6749
SNOMED CT ID
84114007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 2 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Dopexamine DMSCIKZ Approved Small molecular drug [1]
VESNARINONE DMBKX3C Approved Small molecular drug [1]
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This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Relaxin DMLRBCY Phase 3 NA [2]
Autologous skeletal myoblast therapy DMJ3JP9 Phase 2/3 NA [3]
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This Disease is Treated as An Indication in 7 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Piroximone DMQXJDM Discontinued in Phase 3 Small molecular drug [4]
HN-10200 DMYJ1ZB Discontinued in Phase 2 NA [5]
Ad5-AC6 DMQNFZE Terminated NA [6]
BDF-9148 DMV5K0I Terminated Small molecular drug [7]
CK-2289 DM7TRUB Terminated Small molecular drug [8]
Prinoxodan DM29UCU Terminated Small molecular drug [9]
XB-513 DMMYQWZ Terminated Small molecular drug [10]
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⏷ Show the Full List of 7 Drug(s)
This Disease is Treated as An Indication in 5 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
CPI-005 DMYUS42 Investigative NA [11]
CPU-228 DMM8FUT Investigative Small molecular drug [12]
MAD-001 DMEO4VC Investigative NA [11]
MGN-9103 DMACIVP Investigative NA [11]
NSC-119910 DMKHMS4 Investigative Small molecular drug [11]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 397 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ANGPT2 TTKLQTJ Limited Biomarker [13]
APLNR TTJ8E43 Limited Biomarker [14]
EDNRB TT3ZTGU Limited Biomarker [15]
ELAVL1 TTPC9D0 Limited Biomarker [16]
GRK5 TTTCXO0 Limited Altered Expression [17]
HCN4 TTQP04A Limited Biomarker [18]
IL17A TTG0MT6 Limited Altered Expression [19]
MYBPC3 TT9WOBN Limited Genetic Variation [20]
NPR3 TTWVLS6 Limited Biomarker [21]
PIK3CB TT9H4P3 Limited Altered Expression [22]
PPARA TTJ584C Limited Biomarker [23]
PRKCA TTFJ8Q1 Limited Genetic Variation [24]
SLC8A1 TTCF82X Limited Biomarker [25]
TNNI3 TTNLDK6 Limited Biomarker [26]
UTS2 TTERU0T Limited Biomarker [27]
VWF TT3SZBT Limited Biomarker [28]
XDH TT7RJY8 Limited Biomarker [29]
ANGPT1 TTWNQ1T Disputed Biomarker [30]
CAT TTPS279 Disputed Altered Expression [31]
TTR TTPOYU7 Disputed Biomarker [32]
VEGFB TTPJQHE Disputed Biomarker [33]
AIMP2 TTXWHGF moderate Biomarker [34]
BMP10 TTTG6H1 moderate Biomarker [35]
CRK TTFEUYR moderate Biomarker [34]
GATA4 TT1VDN2 moderate Altered Expression [36]
HSF1 TTN6STZ moderate Altered Expression [37]
MMP2 TTLM12X moderate Altered Expression [38]
MYH7 TTNIMDP moderate Genetic Variation [39]
NPPC TTRK0B9 moderate Biomarker [21]
NR3C1 TTOZRK6 moderate Biomarker [40]
PDE5A TTJ0IQB moderate Altered Expression [41]
POSTN TT8ALTZ moderate Biomarker [42]
PRKCB TTYPXQF moderate Altered Expression [43]
SIRT3 TTVZLIJ moderate Biomarker [44]
SLC33A1 TTL69WB moderate Biomarker [45]
UTRN TTNO1VA moderate Biomarker [46]
ABCA4 TTLB52K Strong Biomarker [47]
ABCC9 TTEF5MJ Strong Genetic Variation [48]
ACKR3 TTRQJTC Strong Biomarker [49]
ACLY TT0Z6Y2 Strong Biomarker [50]
ACR TTAHE2N Strong Biomarker [51]
ACVRL1 TTGYPTC Strong Biomarker [52]
ADAM17 TT6AZXG Strong Biomarker [53]
ADCYAP1R1 TT5OREU Strong Biomarker [54]
ADIPOQ TTXKA7D Strong Altered Expression [55]
ADM2 TTM642F Strong Biomarker [56]
ADORA2A TTM2AOE Strong Biomarker [57]
ADORA2B TTNE7KG Strong Altered Expression [58]
ADRA1A TTNGILX Strong Biomarker [49]
ADRA2B TTWM4TY Strong Biomarker [49]
ADRB2 TTG8ZWP Strong Biomarker [59]
ADRB3 TTMXGCW Strong Biomarker [60]
AKR1B1 TTFBNVI Strong Genetic Variation [61]
ALB TTFNGC9 Strong Biomarker [62]
ALDH2 TTFLN4T Strong Biomarker [63]
ALOX15 TTN9T81 Strong Biomarker [64]
AMACR TTLN1AP Strong Biomarker [65]
ANG TTURHFP Strong Biomarker [66]
ANXA5 TT2Z83I Strong Biomarker [67]
APCS TTB7VAT Strong Biomarker [68]
APLN TT87D3J Strong Altered Expression [14]
ARRB1 TTMVD4A Strong Therapeutic [69]
ARRB2 TT8SO2I Strong Biomarker [70]
ARSB TTESQTG Strong Biomarker [71]
ATG7 TTLVB9Z Strong Biomarker [72]
AVP TTJ8EWH Strong Biomarker [70]
AVPR1A TT4TFGN Strong Altered Expression [73]
AVPR1B TTL9MHW Strong Altered Expression [73]
AVPR2 TTK8R02 Strong Biomarker [74]
AXL TTZPY6J Strong Altered Expression [75]
BACE1 TTJUNZF Strong Altered Expression [76]
BAX TTQ57WJ Strong Therapeutic [77]
BGN TT0JPVF Strong Biomarker [78]
BMPR2 TTGKF90 Strong Altered Expression [79]
BRD1 TTT09OB Strong Biomarker [80]
BRS3 TTKYEPM Strong Biomarker [49]
C3AR1 TTI6B3F Strong Biomarker [81]
CA3 TTXUK5D Strong Biomarker [82]
CA5A TT75WPO Strong Genetic Variation [83]
CAD TT2YT1K Strong Biomarker [84]
CALCR TTLWS2O Strong Biomarker [85]
CALR TTUZ7OA Strong Biomarker [85]
CAPN1 TT1WBIJ Strong Biomarker [86]
CASP3 TTPF2QI Strong Biomarker [87]
CCL21 TTLZK1U Strong Altered Expression [88]
CCN2 TTIL516 Strong Altered Expression [89]
CCR2 TTFZYTO Strong Biomarker [90]
CD36 TTPJMCU Strong Altered Expression [91]
CDK8 TTBJR4L Strong Altered Expression [92]
CDK9 TT1LVF2 Strong Biomarker [93]
CETP TTFQAYR Strong Biomarker [94]
CFD TT8D13I Strong Biomarker [95]
CGB3 TTUH273 Strong Altered Expression [96]
CHRM2 TTYEG6Q Strong Altered Expression [97]
CLCN3 TT8XNZ7 Strong Biomarker [98]
CLCNKA TT823N1 Strong Genetic Variation [99]
CNP TT71P0H Strong Biomarker [100]
COX17 TT0F26C Strong Altered Expression [89]
CPB1 TT4UJX5 Strong Biomarker [101]
CRHR1 TT7EFHR Strong Biomarker [102]
CRHR2 TTIY658 Strong Biomarker [103]
CS TTZA6B3 Strong Altered Expression [104]
CSE1L TTTRULD Strong Biomarker [105]
CSF2 TTNYZG2 Strong Biomarker [106]
CSF3 TT5TQ2W Strong Biomarker [107]
CTF1 TTXGTZU Strong Biomarker [108]
CTH TTLQUZS Strong Biomarker [109]
CTSG TTQAJF1 Strong Biomarker [110]
CX3CR1 TT2T98G Strong Biomarker [111]
CXCL2 TTZF0K2 Strong Biomarker [112]
CXCR6 TT2BVUA Strong Biomarker [49]
CYBB TT5T8MR Strong Biomarker [113]
CYP11B2 TT9MNE2 Strong Biomarker [114]
CYP2D6 TTVG215 Strong Biomarker [115]
CYP2J2 TTNE1C7 Strong Biomarker [116]
DAO TT7Y3EJ Strong Biomarker [117]
DBH TTYIP79 Strong Altered Expression [118]
DDIT4 TTVEOY6 Strong Biomarker [119]
DDR1 TTI1FPZ Strong Biomarker [120]
DGAT1 TT0GV3R Strong Biomarker [121]
DMPK TTZQTY2 Strong Biomarker [122]
DNASE1 TTYWGOJ Strong Biomarker [123]
DNM2 TTVRA5G Strong Biomarker [124]
DPP10 TTOVUPC Strong Altered Expression [125]
DPP9 TTNDUL7 Strong Biomarker [126]
DYSF TTA7MXQ Strong Biomarker [127]
ECE1 TTQ9RYT Strong Biomarker [128]
EDNRA TTKRD0G Strong Biomarker [49]
ENAH TTY36UA Strong Altered Expression [129]
ENG TTB30LE Strong Altered Expression [130]
ENPEP TT9PBIL Strong Biomarker [131]
EPHX2 TT7WVHI Strong Biomarker [132]
ERBB4 TTWALCO Strong Genetic Variation [133]
ERN1 TTKIAT3 Strong Biomarker [134]
F10 TTCIHJA Strong Biomarker [135]
F8 TT1290U Strong Biomarker [136]
FADS2 TTT2VDU Strong Genetic Variation [137]
FASN TT7AOUD Strong Biomarker [50]
FDPS TTIKWV4 Strong Biomarker [138]
FDXR TT3W4IX Strong Genetic Variation [61]
FFAR4 TT08JVB Strong Biomarker [139]
FGF4 TTCEKVZ Strong Biomarker [140]
FGFR4 TT1KX2S Strong Biomarker [141]
FKBP1A TTMW94E Strong Biomarker [142]
FST TTDNM9W Strong Biomarker [143]
FSTL3 TTWRPM8 Strong Biomarker [144]
FTO TTFW3BT Strong Biomarker [145]
FURIN TTH9WF6 Strong Biomarker [146]
GAL TTXZAJ5 Strong Biomarker [147]
GAS6 TT69QD2 Strong Biomarker [148]
GCH1 TTLSWP6 Strong Altered Expression [149]
GDF2 TTAP4T1 Strong Altered Expression [130]
GH1 TTT3YKH Strong Biomarker [150]
GHRL TT1OCL0 Strong Therapeutic [151]
GHSR TTWDC17 Strong Altered Expression [97]
GNAQ TTL1SRG Strong Altered Expression [152]
GP1BA TTVB0Q9 Strong Biomarker [153]
GP6 TTTJUVZ Strong Biomarker [153]
GPBAR1 TTSDVTR Strong Biomarker [154]
GPR17 TTMPART Strong Biomarker [155]
GPR35 TT254XD Strong Biomarker [156]
GPRC6A TTI1PRE Strong Biomarker [157]
GRIN1 TTLD29N Strong Altered Expression [158]
GRK3 TT5A4DX Strong Biomarker [159]
GSK3A TTQWAU1 Strong Biomarker [160]
GSK3B TTRSMW9 Strong Biomarker [161]
GSN TTUH7OM Strong Biomarker [162]
GSR TTEP6RV Strong Biomarker [163]
GUSB TTHS7CM Strong Biomarker [164]
HCN2 TT9EUT4 Strong Biomarker [165]
HDAC4 TTTQGH8 Strong Biomarker [166]
HDAC5 TTUELN5 Strong Altered Expression [167]
HDC TTV9GOF Strong Biomarker [168]
HIF1A TTSN6QU Strong Biomarker [169]
HIPK2 TTOB49C Strong Biomarker [170]
HMBS TTT0HW3 Strong Biomarker [171]
HMGB1 TTWQYB7 Strong Biomarker [172]
HMGB2 TTA78JQ Strong Altered Expression [173]
HMOX1 TTI6V2A Strong Biomarker [174]
HP TTLC8E1 Strong Therapeutic [175]
HRC TTR4FKD Strong Genetic Variation [176]
HRH2 TTQHJ1K Strong Biomarker [177]
HSD11B1 TTN7BL9 Strong Biomarker [178]
HSPB1 TT9AZWY Strong Therapeutic [179]
HTR2A TTJQOD7 Strong Biomarker [180]
HTR2B TT0K1SC Strong Biomarker [181]
HTR4 TT07C3Y Strong Biomarker [180]
ID2 TTW8A5N Strong Genetic Variation [182]
IGF1 TTT6LOU Strong Biomarker [183]
IGFBP7 TTUQ01B Strong Biomarker [184]
IL13RA1 TTNEAMG Strong Biomarker [185]
IL1RL1 TT4GZA4 Strong Biomarker [186]
IL6 TTT1V78 Strong Biomarker [187]
ILK TT7ALZG Strong Biomarker [188]
INS TTZOPHG Strong Biomarker [189]
IRF1 TT4TU3L Strong Biomarker [190]
ITGB1 TTBVIQC Strong Biomarker [191]
ITPR1 TT5HWAT Strong Biomarker [192]
ITPR2 TTK9OV3 Strong Altered Expression [193]
ITPR3 TTH1769 Strong Altered Expression [194]
KCNA2 TTVFB0O Strong Biomarker [195]
KCND3 TTPLQO0 Strong Biomarker [196]
KCNH2 TTQ6VDM Strong Biomarker [197]
KCNK3 TTGR91N Strong Biomarker [198]
KCNT1 TTGJFK1 Strong Genetic Variation [199]
KNG1 TTDJ4MY Strong Biomarker [200]
LAMP2 TTULDG7 Strong Biomarker [201]
LCAT TTGZ91P Strong Biomarker [94]
LILRB4 TTREOKA Strong Biomarker [202]
LONP1 TTM1VPZ Strong Biomarker [203]
LOX TTQHNAM Strong Biomarker [204]
LPA TTU9LGY Strong Biomarker [205]
LPAR2 TTB7Y8I Strong Biomarker [49]
LPAR3 TTE2YJR Strong Biomarker [157]
LY75 TTG180Q Strong Biomarker [57]
MANF TT56RYE Strong Biomarker [206]
MAOA TT3WG5C Strong Biomarker [207]
MAP2K7 TT6QY3J Strong Biomarker [208]
MAP3K11 TTETX6Q Strong Biomarker [209]
MAP3K20 TTTUZ3O Strong Biomarker [210]
MAP3K5 TTOQCD8 Strong Biomarker [211]
MAPK14 TTQBR95 Strong Biomarker [212]
MAS1 TTOISYB Strong Biomarker [17]
MC4R TTD0CIQ Strong Genetic Variation [213]
MGAT1 TTYJRN5 Strong Genetic Variation [214]
MRGPRX1 TTIX6PK Strong Biomarker [157]
MS4A1 TTUE541 Strong Biomarker [215]
MSTN TTM8I2X Strong Biomarker [216]
MTTP TTUS1RD Strong Biomarker [217]
MUC16 TTC1PS3 Strong Biomarker [218]
MYLK TT18ETS Strong Biomarker [219]
NAGLU TTDM6HZ Strong Genetic Variation [220]
NCAM1 TTVXPHT Strong Biomarker [221]
NCF1 TTZ4JC3 Strong Biomarker [222]
NFE2L2 TTA6ZN2 Strong Biomarker [223]
NISCH TT789FN Strong Altered Expression [224]
NNT TTKIH76 Strong Genetic Variation [225]
NOD1 TTYSRXM Strong Biomarker [226]
NOS2 TTF10I9 Strong Altered Expression [227]
NOX4 TTQRBSJ Strong Biomarker [228]
NPR1 TTM9IYA Strong Biomarker [229]
NPR2 TTNB7IF Strong Biomarker [230]
NPSR1 TTV1C0Z Strong Biomarker [231]
NPY TT64REZ Strong Biomarker [232]
NPY4R TTW4N16 Strong Altered Expression [233]
NR1H3 TTECBXN Strong Biomarker [234]
NR1H4 TTS4UGC Strong Altered Expression [235]
NR4A1 TTMXE2Q Strong Biomarker [232]
OGDH TTH8T6I Strong Altered Expression [236]
OLR1 TTKSND3 Strong Biomarker [237]
OPA1 TTTU49Q Strong Biomarker [91]
OPRD1 TT27RFC Strong Biomarker [238]
OSM TTIVXSE Strong Altered Expression [239]
OXER1 TT7WBSV Strong Biomarker [157]
OXGR1 TTAS1QK Strong Biomarker [240]
P2RX1 TTJW7B3 Strong Altered Expression [241]
P2RX3 TT2THBD Strong Altered Expression [241]
P2RX4 TT1NLOA Strong Altered Expression [241]
P2RX7 TT473XN Strong Altered Expression [241]
P2RY1 TTA93TL Strong Altered Expression [241]
P2RY2 TTOZHQC Strong Altered Expression [241]
PAM TTF4ZPC Strong Biomarker [242]
PARP1 TTVDSZ0 Strong Biomarker [243]
PCSK9 TTNIZ2B Strong Biomarker [244]
PDE10A TTJW4LU Strong Biomarker [245]
PDE1C TTW2HRK Strong Genetic Variation [246]
PDE3A TT06AWU Strong Altered Expression [247]
PDE4A TTZ97H5 Strong Biomarker [248]
PDE4D TTSKMI8 Strong Altered Expression [247]
PDE9A TTZOEBC Strong Altered Expression [249]
PDGFRA TT8FYO9 Strong Biomarker [250]
PDK1 TTCZOF2 Strong Genetic Variation [251]
PDPK1 TTYMGWX Strong Biomarker [252]
PEBP1 TT1BGU8 Strong Biomarker [253]
PF4 TTSG7Q5 Strong Altered Expression [254]
PGF TT48I1Y Strong Biomarker [255]
PIK3CG TTHBTOP Strong Altered Expression [22]
PIN1 TTJNTSI Strong Altered Expression [256]
PKN1 TTSL41O Strong Biomarker [257]
PKN2 TTTHO0M Strong Biomarker [257]
PLAT TTXAGYU Strong Biomarker [112]
PLCG1 TT6T4JI Strong Genetic Variation [137]
POMC TT21AKM Strong Biomarker [258]
PON1 TT9LX82 Strong Biomarker [259]
PPARG TTT2SVW Strong Altered Expression [260]
PPARGC1B TTKSQ3W Strong Altered Expression [261]
PPIA TTL2ADK Strong Biomarker [262]
PPID TTNAFOU Strong Biomarker [263]
PPIF TTRFQTB Strong Biomarker [263]
PPP3CA TTA4LDE Strong Biomarker [264]
PRKAR2B TTW4Y2M Strong Biomarker [50]
PRKD1 TTSLUMT Strong Biomarker [265]
PRMT1 TTVOJAI Strong Biomarker [266]
PROC TTZUXYS Strong Biomarker [22]
PSEN1 TTZ3S8C Strong Altered Expression [267]
PSEN2 TTWN3F4 Strong Genetic Variation [268]
PTGS1 TT8NGED Strong Biomarker [269]
PTGS2 TTVKILB Strong Biomarker [270]
PTH TT6F7GZ Strong Biomarker [271]
PTPN1 TTELIN2 Strong Biomarker [272]
RAC1 TT2M9CG Strong Biomarker [273]
RACK1 TTJ10AL Strong Biomarker [274]
RAPGEF3 TTOE7I0 Strong Biomarker [275]
RBP4 TT0C8BY Strong Biomarker [276]
RGS2 TTKB7T3 Strong Biomarker [277]
RGS4 TTGTKX9 Strong Altered Expression [278]
RHD TTLCKI8 Strong Genetic Variation [279]
RICTOR TT143WL Strong Biomarker [280]
ROCK1 TTZN7RP Strong Altered Expression [281]
ROCK2 TTGWKQJ Strong Biomarker [282]
RORC TTGV6LY Strong Biomarker [283]
RPGR TTHBDA9 Strong Biomarker [284]
RYR1 TTU5CIX Strong Biomarker [285]
S1PR1 TT9JZCK Strong Genetic Variation [286]
SCD TT6RIOV Strong Biomarker [287]
SCN5A TTZOVE0 Strong Altered Expression [288]
SELP TTE5VG0 Strong Biomarker [289]
SEMA4D TT5UT28 Strong Biomarker [290]
SERPINE1 TTTO43N Strong Biomarker [78]
SGCA TTS9Q5V Strong Biomarker [291]
SGK1 TTTV8EJ Strong Biomarker [292]
SHCBP1 TTZ9WGL Strong Biomarker [242]
SIK3 TTW6L4V Strong Genetic Variation [137]
SIRT1 TTUF2HO Strong Biomarker [293]
SIRT6 TTUXYWF Strong Biomarker [294]
SLC18A3 TTV8KWS Strong Altered Expression [295]
SLC30A8 TTXIGT7 Strong Altered Expression [43]
SLC5A1 TT2UE56 Strong Biomarker [296]
SLC6A2 TTAWNKZ Strong Altered Expression [297]
SLC6A8 TTYUHB5 Strong Biomarker [85]
SLC9A1 TTGSEFH Strong Biomarker [298]
SLC9A3 TTFZVPO Strong Biomarker [299]
SLCO1B1 TTFGXEB Strong Genetic Variation [300]
SLCO1B3 TTU86P0 Strong Genetic Variation [300]
SMPD2 TTE5VI6 Strong Biomarker [301]
SOD1 TTP9K3Q Strong Biomarker [269]
SOD2 TT9O4C5 Strong Altered Expression [302]
SPTBN1 TTS9BDA Strong Biomarker [303]
SRGN TTCHB06 Strong Biomarker [304]
SSTR4 TTAE1BR Strong Biomarker [49]
STC1 TTDLUER Strong Altered Expression [305]
STC2 TT4EFTR Strong Biomarker [306]
SUGT1 TT7Q9WR Strong Biomarker [307]
TAGLN TTDRZ9H Strong Altered Expression [308]
TCF7L2 TT80QAL Strong Genetic Variation [137]
TCL1A TTUKRDV Strong Altered Expression [309]
TERF2 TT5XSLT Strong Altered Expression [310]
TH TTUHP71 Strong Altered Expression [311]
THRA TTTSEPU Strong Biomarker [312]
TLR2 TTY7ZHS Strong Biomarker [313]
TMSB4X TTMVAIU Strong Biomarker [314]
TNFRSF10B TTW20TU Strong Biomarker [143]
TNFRSF11B TT2CJ75 Strong Biomarker [143]
TNFRSF12A TTKPS7V Strong Altered Expression [315]
TNFRSF1A TTG043C Strong Biomarker [316]
TNFSF12 TTBTDM1 Strong Altered Expression [315]
TNNC1 TT8RDXP Strong Biomarker [317]
TNNT2 TTWAS18 Strong Biomarker [318]
TOP2B TT4NVEM Strong Genetic Variation [319]
TPCN1 TTODQE2 Strong Altered Expression [192]
TPCN2 TTHQJ2Y Strong Altered Expression [192]
TRAF6 TTCDR6M Strong Biomarker [320]
TRPC1 TTA76X0 Strong Biomarker [321]
TRPC6 TTRBT3W Strong Altered Expression [322]
TRPM4 TTJ2HKA Strong Biomarker [323]
TRPV1 TTMI6F5 Strong Biomarker [324]
TRPV2 TTBECWA Strong Altered Expression [325]
TXN TTZJ5U9 Strong Biomarker [326]
TXNRD3 TTDYFVB Strong Biomarker [327]
UCP1 TTI12YJ Strong Biomarker [328]
UCP3 TT12RJK Strong Biomarker [329]
UTS2R TTW5UDX Strong Biomarker [27]
VEGFA TT3LJ9K Strong Biomarker [330]
VEGFD TTOM5H4 Strong Genetic Variation [331]
VKORC1 TTEUC8H Strong Genetic Variation [332]
ALOX12 TT12ABZ Definitive Biomarker [333]
BECN1 TT5M7LN Definitive Therapeutic [334]
BIRC5 TTTPU1G Definitive Biomarker [335]
CHRM4 TTQ3JTF Definitive Biomarker [120]
CHRNA4 TT4H1MQ Definitive Biomarker [120]
CYP11B1 TTIQUX7 Definitive Biomarker [336]
DNMT1 TT6S2FE Definitive Biomarker [337]
FAS TT7LTUJ Definitive Therapeutic [77]
FASLG TTO7014 Definitive Therapeutic [77]
FOS TTOM5AU Definitive Biomarker [338]
FOSL1 TTY8LZG Definitive Biomarker [338]
FTH1 TT975ZT Definitive Biomarker [339]
LIF TTGZ5WN Definitive Biomarker [340]
MMP13 TTHY57M Definitive ModifyingMutation [341]
MMP14 TTJ4QE7 Definitive ModifyingMutation [341]
MMP8 TTGA1IV Definitive ModifyingMutation [341]
NGFR TTEDJN4 Definitive Biomarker [120]
PLD2 TTRLMKF Definitive Biomarker [342]
PTK2B TTTEFBV Definitive Biomarker [343]
SCN8A TT54ERL Definitive Biomarker [344]
TRPC3 TTNVC34 Definitive Biomarker [293]
UCP2 TTSC2YM Definitive Biomarker [345]
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⏷ Show the Full List of 397 DTT(s)
This Disease Is Related to 15 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCB7 DT2IMBW Strong Biomarker [346]
ATP2B1 DTJWQ1L Strong Genetic Variation [137]
KCNK2 DTENHUP Strong Biomarker [347]
SLC12A2 DTHKL3Q Strong Biomarker [348]
SLC22A5 DT3HUVD Strong Genetic Variation [349]
SLC24A3 DTO18LP Strong Biomarker [350]
SLC27A6 DTG4CWJ Strong Genetic Variation [351]
SLC30A10 DTYBI73 Strong Altered Expression [43]
SLC30A3 DTKMECW Strong Genetic Variation [137]
SLC35A1 DTVZIRG Strong Biomarker [352]
SLC39A14 DTZ6IJW Strong Altered Expression [43]
SLC39A8 DTLPQGT Strong Altered Expression [43]
SLC4A1 DTB0Q3P Strong Biomarker [353]
SLC4A3 DT4X2AH Strong Biomarker [354]
SLC9C1 DT9J8DO Strong Biomarker [355]
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⏷ Show the Full List of 15 DTP(s)
This Disease Is Related to 20 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
CHDH DEAHED0 Limited Biomarker [356]
ACP5 DESITDW Strong Genetic Variation [357]
ALAS2 DE437BY Strong Altered Expression [358]
ALDH1A2 DEKN1H4 Strong Genetic Variation [137]
APRT DE2MV1R Strong Biomarker [359]
CBR3 DEIVKZ8 Strong Genetic Variation [360]
CMPK1 DEMPH4I Strong Biomarker [361]
CRMP1 DE0EUXB Strong Biomarker [46]
DDAH1 DEY0TQC Strong Biomarker [362]
FADS1 DE05S8C Strong Genetic Variation [137]
FXN DEXVHDB Strong Biomarker [363]
MAT2B DEKF1OH Strong Biomarker [327]
ME1 DE97WM8 Strong Altered Expression [364]
NNMT DECVGJ3 Strong Biomarker [365]
OPLAH DEJ1LMB Strong Biomarker [366]
PCK1 DEPLH5Z Strong Biomarker [50]
PON2 DEHJU7E Strong Biomarker [367]
SULT1E1 DESTKG6 Strong Biomarker [368]
UGT2B7 DEB3CV1 Strong Biomarker [369]
DIO3 DET89OV Definitive Biomarker [370]
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⏷ Show the Full List of 20 DME(s)
This Disease Is Related to 488 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AMPD1 OTU17BCI Limited Genetic Variation [371]
BAG3 OTVXYUDQ Limited Biomarker [372]
BAMBI OTCEJ8W5 Limited Biomarker [282]
CHGA OTXYX5JH Limited Biomarker [352]
CST3 OTNZ6AO4 Limited Biomarker [373]
DSTN OTMXO4YB Limited Biomarker [282]
FSD1 OT8P6PT3 Limited Biomarker [374]
FSD1L OTBQ48RF Limited Biomarker [374]
IGFBP4 OT2HZRBD Limited Biomarker [306]
KLF15 OTGMQMVR Limited Biomarker [375]
MTPN OT5N60RU Limited Biomarker [376]
PITX2 OTWMXAOY Limited Genetic Variation [377]
RLN2 OTY3OG71 Limited Biomarker [378]
SOX4 OTSS40SS Limited Biomarker [282]
TBX20 OTMPU2XQ Limited Biomarker [282]
REG1A OTMHUH1D Disputed Genetic Variation [379]
S100A1 OT1F2G4J Disputed Biomarker [380]
TM7SF2 OTILU5S7 Disputed Biomarker [30]
TTN OT0LZ058 Disputed Biomarker [381]
AHSA1 OTC7AFHT moderate Biomarker [34]
ANKRD1 OTHJ7JV9 moderate Biomarker [382]
ATP6AP2 OT0IABVV moderate Biomarker [383]
CASQ2 OT09MNQ8 moderate Genetic Variation [384]
GRAP2 OTS5NIZ3 moderate Biomarker [34]
HAVCR1 OT184CRZ moderate Biomarker [385]
HSPB7 OTLATAOV moderate Biomarker [386]
MEF2A OTV2SF6E moderate Biomarker [387]
MYH6 OT3YNCH1 moderate Biomarker [388]
POLDIP2 OT8SZSJ6 moderate Biomarker [34]
PVALB OTZW1WVQ moderate Biomarker [389]
RNF19A OTKWCV80 moderate Biomarker [34]
SGCD OTRBL3NQ moderate Genetic Variation [390]
TOR2A OT1EGCDU moderate Altered Expression [391]
ACACA OT5CQPZY Strong Biomarker [392]
ACADM OTA4P0FC Strong Altered Expression [393]
ACADS OTGFANYQ Strong Biomarker [394]
ACTC1 OTJU04B1 Strong Genetic Variation [395]
ADAMTS16 OTTKUH99 Strong Altered Expression [38]
ADAMTSL1 OTBNYF3F Strong Genetic Variation [396]
ADCY10 OTYSTB0R Strong Biomarker [397]
ADCY6 OTFOY4WW Strong Biomarker [398]
ADD1 OTTF68DC Strong Genetic Variation [399]
ADI1 OT8IOD03 Strong Genetic Variation [400]
ADO OTRLGQ7V Strong Biomarker [401]
AFDN OTTRU341 Strong Biomarker [402]
AGGF1 OTA7U2T8 Strong Biomarker [403]
AK3 OTM59ZGG Strong Genetic Variation [404]
AK6 OT84OHHP Strong Genetic Variation [405]
AKAP1 OTIIB2JB Strong Biomarker [406]
AKAP12 OTCVRDDX Strong Biomarker [407]
ALDH7A1 OTV57BZD Strong Biomarker [408]
ALYREF OTOF2ADD Strong Biomarker [409]
AMBP OTLU8GU8 Strong Biomarker [246]
AMZ1 OTDH9XM0 Strong Biomarker [410]
ANGPTL2 OTB6JG41 Strong Biomarker [411]
ANK2 OTWB4R1Y Strong Altered Expression [412]
ANKS1B OT26DGM9 Strong Genetic Variation [83]
ANXA6 OT9KIQ0Y Strong Altered Expression [413]
APIP OT8ZABOU Strong Altered Expression [58]
APOC1 OTA58CED Strong Biomarker [50]
APOF OT12S5QS Strong Biomarker [414]
AQP2 OTQLBKK6 Strong Altered Expression [415]
ARC OTN2QQPG Strong Biomarker [416]
ARHGEF5 OTUVGFT9 Strong Biomarker [385]
ARSD OTAHW9M8 Strong Biomarker [417]
ARSL OTF1VTCR Strong Biomarker [418]
ASB14 OTQT4M45 Strong Biomarker [190]
ASXL1 OTX931AW Strong Biomarker [419]
ATP1A3 OTM8EG6H Strong Biomarker [420]
ATP2A1 OT959A3A Strong Biomarker [421]
ATP2A3 OTFYDEES Strong Biomarker [422]
ATP2B4 OTMWFDAC Strong Biomarker [423]
ATP5F1A OT3FZDLX Strong Biomarker [350]
ATXN1 OTQF0HNR Strong Biomarker [87]
AZIN2 OT8OB7CG Strong Biomarker [424]
BAZ1B OTD5KR2J Strong Genetic Variation [137]
BCL2L12 OTS6IFZY Strong Altered Expression [425]
BDH1 OT62RL5P Strong Biomarker [426]
BEX1 OTBQIF0H Strong Altered Expression [427]
BFAR OTTBG0V7 Strong Altered Expression [235]
BIN1 OTK8O0X8 Strong Biomarker [428]
BIRC6 OTCQJAB0 Strong Genetic Variation [429]
BMPR1A OTQOA4ZH Strong Altered Expression [430]
BNIP3 OT4SO7J4 Strong Biomarker [431]
BNIP3L OTJKOMXE Strong Altered Expression [432]
BTBD8 OT3A3RD7 Strong Genetic Variation [433]
BTD OTJYTQ69 Strong Biomarker [434]
BVES OT4GT1WC Strong Altered Expression [435]
C1orf21 OTMD7O88 Strong Genetic Variation [83]
C1QTNF1 OT7I7KHC Strong Biomarker [436]
C1QTNF9 OTLI3VA3 Strong Biomarker [437]
CACNG6 OT2PC1E1 Strong Biomarker [438]
CALCOCO2 OTRGX0OV Strong Biomarker [439]
CAMK2D OTJ5XLVU Strong Biomarker [440]
CAPG OTJ86KI6 Strong Biomarker [441]
CAST OTBXZZGF Strong Genetic Variation [442]
CASZ1 OTWJ2OR8 Strong Biomarker [352]
CAV3 OTWSFDB4 Strong Altered Expression [443]
CBLIF OTNE20WU Strong Biomarker [444]
CCL19 OTQ2UJMH Strong Altered Expression [88]
CCN3 OTOW5YL4 Strong Altered Expression [445]
CCN5 OTADU8JJ Strong Biomarker [446]
CCS OTXHT3QO Strong Genetic Variation [447]
CDH15 OTJ1TO02 Strong Altered Expression [393]
CDK5RAP3 OTC0Q2QS Strong Altered Expression [448]
CDS1 OT2F591M Strong Altered Expression [449]
CDS2 OTKC393S Strong Altered Expression [449]
CELSR1 OT7PS8O1 Strong Genetic Variation [83]
CELSR2 OTON6JSZ Strong Genetic Variation [137]
CENPJ OTZCQZN5 Strong Biomarker [450]
CERT1 OTNUCNHX Strong Genetic Variation [137]
CHAMP1 OTBGWU86 Strong Biomarker [451]
CHGB OT7SAQT2 Strong Altered Expression [96]
CIDEA OTDUTSOV Strong Biomarker [50]
CIRBP OTXWTPBL Strong Altered Expression [452]
CLDN10 OT2CVAKY Strong Biomarker [453]
CMPK2 OTOG90R0 Strong Biomarker [361]
CMTM7 OTI7Q2JW Strong Genetic Variation [454]
CNN1 OTVPG39Z Strong Biomarker [455]
CNOT3 OT4D5Z9L Strong Biomarker [72]
CNPY2 OTGY8ESX Strong Altered Expression [456]
CNTN5 OTWU5FLZ Strong Genetic Variation [457]
CORIN OT4SK7DK Strong Altered Expression [458]
CPNE5 OTU882I6 Strong Genetic Variation [83]
CPT1A OTI862QH Strong Biomarker [459]
CPT2 OTIN6G20 Strong Biomarker [459]
CRABP1 OTISDG5X Strong Biomarker [460]
CREBZF OTO3TOEU Strong Biomarker [461]
CREM OTJIJ5AL Strong Biomarker [198]
CRX OTH435SV Strong Biomarker [284]
CRYGC OTYSTQWI Strong Biomarker [462]
CSRP3 OTECBJMV Strong Biomarker [463]
CTCF OT8ZB70U Strong Altered Expression [380]
CTNNA1 OTFC725Z Strong Biomarker [464]
CTRL OTB6NA5O Strong Altered Expression [465]
CYTH3 OTBXAT3Z Strong Genetic Variation [83]
CYTL1 OTLYUPUY Strong Biomarker [466]
DAPK2 OTWODUQG Strong Biomarker [46]
DBP OTE0W7LN Strong Altered Expression [467]
DCAF6 OT3EYK1J Strong Biomarker [468]
DDT OTF5HTYL Strong Altered Expression [469]
DECR1 OTCDIR6X Strong Biomarker [470]
DENR OTXP9HOY Strong Biomarker [46]
DGLUCY OTZD17IM Strong Altered Expression [471]
DHRS7C OTVU4R2D Strong Altered Expression [472]
DNAAF1 OTYLQLHO Strong Biomarker [473]
DNAH8 OTGES2OU Strong Biomarker [474]
DNER OT2GH2E5 Strong Biomarker [475]
DNM1L OTXK1Q1G Strong Altered Expression [476]
DPP3 OTUIVL1C Strong Biomarker [477]
DSG2 OTJPB2TO Strong Genetic Variation [478]
DSP OTB2MOP8 Strong Genetic Variation [479]
DUOX1 OTQ2AEW0 Strong Altered Expression [222]
DUOX2 OTU14HCN Strong Altered Expression [222]
DUSP2 OTH54FMR Strong Biomarker [54]
DYNLL1 OTR69LHT Strong Altered Expression [480]
E2F6 OT2PN28R Strong Biomarker [426]
ECD OT3L3PCU Strong Biomarker [307]
EHD2 OTTX391J Strong Biomarker [127]
EHD3 OTOKC2G5 Strong Biomarker [481]
EIF3K OTGTKVGO Strong Biomarker [482]
ELAVL2 OT6EJ8MQ Strong Biomarker [483]
ELOVL6 OTB26UJJ Strong Biomarker [50]
EMB OT67E3Q1 Strong Biomarker [484]
EMC10 OTQ6S50X Strong Biomarker [485]
EMD OTR8ZANE Strong Biomarker [486]
ENHO OT91QASK Strong Biomarker [487]
ERBIN OTNWTUA8 Strong Biomarker [488]
ETV3 OTEN03BM Strong Genetic Variation [489]
EVA1A OTCY3Q2M Strong Biomarker [490]
EYA4 OTINGR3Z Strong Altered Expression [491]
FAM20C OTW5YZ7X Strong Biomarker [492]
FAM53B OTVD7OU6 Strong Biomarker [493]
FASTK OTTHFZMP Strong Altered Expression [494]
FBL OTRODIE5 Strong Biomarker [495]
FBLN1 OT5MHHOP Strong Altered Expression [496]
FBLN5 OTLVNZ8U Strong Biomarker [497]
FERMT2 OTZNPWWX Strong Biomarker [498]
FHAD1 OT4D6XH0 Strong Altered Expression [499]
FIP1L1 OTF91GTL Strong Biomarker [250]
FKRP OTMUZ7GH Strong Genetic Variation [500]
FKTN OTQ9GCXL Strong Biomarker [501]
FMOD OT9EJ5H8 Strong Altered Expression [502]
FRMD4B OTVI6YFP Strong Genetic Variation [503]
FRY OT74IAG2 Strong Altered Expression [504]
FRZB OTTO3DPY Strong Altered Expression [505]
FSTL1 OT6KEZUD Strong Biomarker [506]
FUNDC1 OTA6IVKQ Strong Altered Expression [507]
FXYD1 OTNKT6GP Strong Biomarker [508]
FZD4 OTGLZIE0 Strong Biomarker [157]
GAB1 OTQKE6V4 Strong Genetic Variation [509]
GAL3ST1 OTSFFZRD Strong Biomarker [352]
GALNT1 OTO3RO36 Strong Biomarker [510]
GATM OTIJ4Z11 Strong Altered Expression [511]
GCKR OTSIWXGG Strong Genetic Variation [137]
GDF11 OTOSNMND Strong Biomarker [512]
GNA12 OT3IRZH3 Strong Biomarker [47]
GNB3 OTA6HYBA Strong Genetic Variation [513]
GNL2 OTURD1GV Strong Genetic Variation [514]
GNLY OTZJKA8C Strong Biomarker [515]
GNPTAB OT2Z03OB Strong Biomarker [516]
GOLGB1 OT2S0GK8 Strong Biomarker [297]
GPD1L OTVLWW9T Strong Biomarker [517]
GPR151 OT7EACU6 Strong Biomarker [157]
GPR42 OTEB0ROY Strong Biomarker [49]
GPX4 OTRAFFX2 Strong Biomarker [269]
GRHL1 OTZ4MNEW Strong Genetic Variation [137]
GTPBP3 OTU52TXX Strong Genetic Variation [518]
GUCA2B OTZERX04 Strong Biomarker [519]
HADH OTJDOL20 Strong Altered Expression [520]
HADHA OTO557N2 Strong Biomarker [449]
HAND1 OTN4IPVV Strong Genetic Variation [521]
HAND2 OTCXYW4Y Strong Biomarker [282]
HGS OTCYYCAC Strong Biomarker [522]
HIPK3 OT4WYQM2 Strong Biomarker [523]
HLA-C OTV38BUJ Strong Biomarker [298]
HNRNPD OT5UO1FA Strong Biomarker [524]
HOPX OTBSR6C9 Strong Altered Expression [525]
HSF2 OTXNJIJ9 Strong Biomarker [526]
HSPA4 OT5HR0AR Strong Altered Expression [527]
IKBKG OTNWJWSD Strong Altered Expression [528]
IL17RA OTVVI8ER Strong Genetic Variation [529]
IL18BP OTW0LRYZ Strong Biomarker [530]
IL34 OTZ15VVK Strong Altered Expression [531]
IL6R OTCQL07Z Strong Biomarker [532]
IL6ST OT1N9C70 Strong Biomarker [533]
ILF3 OTKMZ5K5 Strong Biomarker [534]
IMPACT OTQ923OB Strong Biomarker [535]
INSL6 OTF8OJQC Strong Biomarker [536]
INSRR OT3F75WA Strong Genetic Variation [537]
ISYNA1 OT49ONSE Strong Altered Expression [227]
ITGA2B OT4Y17PY Strong Biomarker [538]
ITGB1BP2 OTHYX9F3 Strong Genetic Variation [539]
ITPK1 OTP4PGL6 Strong Genetic Variation [137]
JAML OTOJHNEV Strong Biomarker [540]
JARID2 OT14UM8H Strong Altered Expression [541]
JDP2 OTW35WKX Strong Biomarker [542]
JPH2 OTL9YH7V Strong Biomarker [543]
KAT8 OT5LPQTR Strong Biomarker [544]
KCNE1 OTZNQUW9 Strong Genetic Variation [545]
KCNE2 OTUO214Y Strong Biomarker [546]
KCNIP2 OTY4BLOJ Strong Altered Expression [547]
KCNIP3 OTCQPEM4 Strong Biomarker [548]
KCNK13 OTMOT2KX Strong Altered Expression [549]
KCP OTIS86DZ Strong Biomarker [550]
KLF13 OTMIKHZ4 Strong Biomarker [551]
KLF14 OT8BXLBS Strong Biomarker [552]
KLF2 OTIP1UFX Strong Biomarker [553]
KMT2B OTMMAZQX Strong Biomarker [554]
LAD1 OT6YGTVX Strong Biomarker [555]
LGALS13 OTEV3DD7 Strong Biomarker [556]
LGR6 OTPZ1PWR Strong Biomarker [157]
LIAS OTOSW67J Strong Biomarker [557]
LIPC OTZY5SC9 Strong Genetic Variation [137]
LMOD2 OTFXHQFL Strong Biomarker [558]
LRIT1 OTNEQPMZ Strong Biomarker [242]
LRPPRC OTXSK5LP Strong Biomarker [533]
LTBP2 OTS88GSD Strong Altered Expression [559]
LTBP3 OTME98V7 Strong Altered Expression [560]
LUC7L3 OTKDED8A Strong Biomarker [561]
LUM OTSRC874 Strong Altered Expression [562]
LYST OTIUB1B3 Strong Genetic Variation [563]
MAML3 OTZFV53Z Strong Genetic Variation [137]
MAP2K3 OTI2OREX Strong Biomarker [514]
MAP3K12 OT5HODDD Strong Biomarker [210]
MAP3K13 OTS93BTX Strong Biomarker [210]
MAP3K7CL OT9J7RLC Strong Genetic Variation [377]
MAP4K5 OTUFGLXE Strong Biomarker [514]
MAP6 OTPUI00F Strong Biomarker [564]
MARCHF1 OTI2EYO6 Strong Biomarker [565]
MARCHF6 OTBTA03N Strong Biomarker [566]
MARCKSL1 OT13J2FM Strong Biomarker [567]
MATN1 OTBRTCTQ Strong Biomarker [568]
MB OTYWYL2D Strong Biomarker [569]
MCIDAS OTK1JVAH Strong Biomarker [570]
MCU OTQZAYWQ Strong Biomarker [571]
MDFIC OTSRYBWZ Strong Biomarker [572]
MEF2C OTZGF1Y5 Strong Altered Expression [573]
MEOX1 OTJEMT2D Strong Altered Expression [574]
METTL3 OTSXP1M3 Strong Biomarker [575]
MFAP1 OTZN4FT3 Strong Biomarker [359]
MFN1 OTCBXQZF Strong Altered Expression [576]
MFN2 OTPYN8A3 Strong Altered Expression [577]
MGP OTZWU3FU Strong Biomarker [578]
MLC1 OTCNZLSP Strong Biomarker [579]
MLEC OTOPGRF5 Strong Genetic Variation [307]
MLIP OTMT7AII Strong Genetic Variation [405]
MMP28 OTHQZXM1 Strong Altered Expression [580]
MMUT OTBBBV70 Strong Genetic Variation [581]
MOCOS OT0TL3Q5 Strong Biomarker [582]
MOK OTQK7M9V Strong Biomarker [583]
MON2 OTCSVMAR Strong Biomarker [584]
MOV10L1 OTP978LK Strong Biomarker [451]
MPI OTBH6ZK1 Strong Genetic Variation [585]
MPRIP OT5FV5NS Strong Genetic Variation [586]
MRGPRX3 OTRKCCDS Strong Biomarker [157]
MRGPRX4 OTOBHZVA Strong Biomarker [157]
MTG1 OTC9U1LI Strong Biomarker [587]
MTO1 OT7HCZ1D Strong Genetic Variation [518]
MUC2 OT3X4QVX Strong Biomarker [567]
MYF6 OTLLMHMI Strong Biomarker [588]
MYH14 OT1TZEJK Strong Altered Expression [589]
MYL2 OT78PC0C Strong Biomarker [590]
MYL3 OTKD3RSX Strong Genetic Variation [591]
MYL4 OTURFCSE Strong Altered Expression [592]
MYL7 OT7ZNDP4 Strong Biomarker [541]
MYLK3 OTC58V2Q Strong Genetic Variation [593]
MYOC OT6DAHNF Strong Biomarker [594]
MYOCD OTSJNHTH Strong Altered Expression [595]
MYOM3 OT8GGH11 Strong Posttranslational Modification [89]
NAE1 OTMC6F3Y Strong Biomarker [596]
NBAS OTW9IBRI Strong Genetic Variation [220]
NDUFAB1 OTF906UR Strong Biomarker [597]
NEDD4L OT1B19RU Strong Biomarker [598]
NFATC2 OTK5T6HZ Strong Biomarker [599]
NFATC4 OTTDCUAO Strong Altered Expression [600]
NFE2L1 OT1QHOS2 Strong Biomarker [534]
NFIL3 OTQH9HM3 Strong Biomarker [601]
NLK OT2LETFS Strong Biomarker [602]
NLN OTFRITPU Strong Altered Expression [603]
NLRP6 OTEREN4W Strong Biomarker [604]
NME3 OT0CA0GF Strong Biomarker [605]
NOS1AP OTDFOBRU Strong Biomarker [606]
NOX1 OTZPJQCC Strong Biomarker [269]
NOX3 OT0FFJH8 Strong Altered Expression [607]
NPPA OTMQNTNX Strong Biomarker [608]
NR2E3 OTO3GBHQ Strong Biomarker [155]
NRBP2 OTJSTU62 Strong Biomarker [439]
NRF1 OTOXWNV8 Strong Biomarker [534]
NRIP1 OTIZOJQV Strong Biomarker [609]
NSD2 OTQ6SW4R Strong Biomarker [610]
NUBPL OTQMCSXT Strong Genetic Variation [83]
OGA OT7ZBWT1 Strong Altered Expression [611]
OGN OTKP5S4L Strong Biomarker [612]
OMA1 OT0JRVY7 Strong Biomarker [613]
OPN1MW OTPJ7LX4 Strong Biomarker [297]
OPN4 OT1LZ7TS Strong Altered Expression [603]
OPTC OTCASGO0 Strong Genetic Variation [146]
ORAI3 OTUP3OH3 Strong Posttranslational Modification [614]
ORM1 OTZKSBRE Strong Biomarker [350]
OSBP2 OTDGLB4J Strong Biomarker [615]
OTUD7A OT3GCY98 Strong Genetic Variation [454]
P2RX2 OT0LF34A Strong Altered Expression [241]
P2RX5 OTLBR20R Strong Altered Expression [241]
P2RX6 OT1FNTXA Strong Altered Expression [241]
PAFAH1B1 OT9T2TCJ Strong Biomarker [419]
PAPPA OTTTG9PG Strong Genetic Variation [616]
PCGF2 OTIY1J5L Strong Biomarker [526]
PCMT1 OTGYVSGU Strong Biomarker [617]
PDC OT1UUVYY Strong Biomarker [618]
PDK4 OTCMHMBZ Strong Biomarker [619]
PDS5A OT34P56Z Strong Biomarker [620]
PDS5B OT3U3X8Z Strong Genetic Variation [620]
PDSS2 OTEOQBMX Strong Biomarker [621]
PENK OT8P3HMP Strong Altered Expression [622]
PFN1 OTHTGA1H Strong Biomarker [623]
PGK1 OT6V1ICH Strong Biomarker [624]
PHLDA3 OTXFUDO2 Strong Biomarker [625]
PICK1 OT8QE6EU Strong Biomarker [626]
PIEZO1 OTBG1FU4 Strong Altered Expression [627]
PIGF OTJKE6VW Strong Biomarker [255]
PINK1 OT50NR57 Strong Biomarker [628]
PITX3 OTE2KT8P Strong Biomarker [629]
PKD2 OTIXBU8H Strong Genetic Variation [630]
PKP2 OTJOVF68 Strong Genetic Variation [631]
PLIN5 OTV8G50L Strong Biomarker [632]
PLPP3 OTSSF7BK Strong Altered Expression [633]
PLSCR4 OT2AMYLY Strong Biomarker [634]
PNPLA2 OTR3ERMR Strong Biomarker [635]
POFUT1 OTOBJZIT Strong Altered Expression [636]
POLK OTKZ38JH Strong Genetic Variation [137]
POLR2A OTHJQ1DZ Strong Altered Expression [624]
PPA1 OTHZK1QB Strong Altered Expression [233]
PPARGC1A OTHCDQ22 Strong Biomarker [637]
PPBP OT1FHGQS Strong Genetic Variation [638]
PPIG OTZ8BTTM Strong Biomarker [639]
PPM1K OTNZ4N4E Strong Biomarker [640]
PPP1CB OTYFTYFR Strong Altered Expression [641]
PPP1CC OTRZO26U Strong Altered Expression [641]
PPP1R12A OT4AVU95 Strong Altered Expression [589]
PPP1R18 OT0JVGOZ Strong Biomarker [641]
PPP1R1A OTGTAGCV Strong Biomarker [642]
PPP1R3A OTJL9VYP Strong Biomarker [643]
PPP1R7 OTY5IE69 Strong Biomarker [641]
PPP2R1A OTYA3GB4 Strong Altered Expression [644]
PRDM16 OT0BGA27 Strong Biomarker [328]
PRDX3 OTLB2WEU Strong Altered Expression [645]
PRKAA1 OT7TNF0L Strong Biomarker [646]
PRKAA2 OTU1KZPV Strong Biomarker [646]
PRKAB1 OT1OG4QZ Strong Biomarker [646]
PRKAG2 OTHTAM54 Strong Genetic Variation [647]
PRRT2 OTCJUBDO Strong Altered Expression [43]
PSMG1 OTZ5I6UM Strong Biomarker [54]
PTPA OTRGFOI7 Strong Altered Expression [644]
PTX3 OTPXHRKU Strong Biomarker [629]
PURB OTCDDKYB Strong Altered Expression [648]
QRSL1 OTJDU2UG Strong Genetic Variation [649]
RAB1A OTKPHRD0 Strong Altered Expression [650]
RASA4 OTW0178L Strong Biomarker [651]
RBFOX2 OTXY1WVH Strong Biomarker [543]
RBM10 OTES2MES Strong Altered Expression [652]
RBM20 OTOQZNKS Strong Biomarker [653]
RBM24 OTQI1AR1 Strong Biomarker [654]
RBM25 OTVOUOAG Strong Biomarker [655]
REEP5 OTZU4TJI Strong Biomarker [656]
RETN OTW5Z1NH Strong Altered Expression [657]
RHOU OTERIAD4 Strong Altered Expression [658]
RIPK3 OTL1D484 Strong Genetic Variation [586]
RMC1 OT7K8MTJ Strong Biomarker [659]
RMDN1 OTE1NB6U Strong Biomarker [660]
RMDN2 OTK5WSFI Strong Biomarker [660]
RMDN3 OTKO7AUM Strong Biomarker [660]
RND3 OTXMXPIH Strong Biomarker [661]
RNF111 OTO3QT6Q Strong Altered Expression [662]
RPL32 OTKRQJT4 Strong Biomarker [624]
RRAD OTW2O4GD Strong Altered Expression [663]
RYR2 OT0PF19E Strong Biomarker [324]
RYR3 OT4EHIP4 Strong Biomarker [664]
SCARA3 OT46I38Y Strong Biomarker [665]
SCARB2 OTN929M8 Strong Biomarker [666]
SCG2 OTXWUQQL Strong Biomarker [667]
SCGN OTGD7SKH Strong Biomarker [668]
SCN7A OTK05PXY Strong Genetic Variation [220]
SDC4 OTKUVUGZ Strong Biomarker [669]
SEMA5B OTUVSKK0 Strong Genetic Variation [137]
SERPINA5 OTTZXPGD Strong Biomarker [670]
SFTPB OTOHS07E Strong Biomarker [671]
SGTA OTKOJ3JB Strong Biomarker [307]
SLMAP OTHW3DVC Strong Biomarker [672]
SLN OTERIU75 Strong Altered Expression [673]
SLPI OTUNFUU8 Strong Altered Expression [52]
SLU7 OTZUUICN Strong Altered Expression [655]
SMCP OTXKY794 Strong Biomarker [582]
SMYD1 OTPAH75C Strong Genetic Variation [674]
SOD3 OTIOZQAB Strong Genetic Variation [675]
SPEG OTQXWJR4 Strong Biomarker [581]
SPON1 OTC06MY4 Strong Biomarker [143]
SPRR2B OTQ9WPKY Strong Biomarker [676]
SPTAN1 OT6VY3A3 Strong Biomarker [677]
SRF OTW18FQN Strong Biomarker [678]
SRI OT4R3EAC Strong Biomarker [679]
SSB OTCCTPBR Strong Genetic Variation [680]
STIM1 OT8CLQ1W Strong Biomarker [681]
STRN OTLOZL5I Strong Biomarker [682]
STUB1 OTSUYI9A Strong Biomarker [683]
SUCLA2 OTMZD4PW Strong Biomarker [684]
SUCO OT3I9VO9 Strong Genetic Variation [146]
SUGP1 OT7W0EB8 Strong Genetic Variation [137]
SUMO1 OTJFD4P5 Strong Altered Expression [685]
SUMO2 OT1Y5IKN Strong Biomarker [686]
SUMO3 OTTUJQJ1 Strong Biomarker [686]
SYBU OT3FQV7N Strong Biomarker [660]
SYCP3 OTKOF54H Strong Biomarker [687]
SYPL2 OT6CV0CA Strong Biomarker [688]
TCFL5 OTJL4348 Strong Biomarker [689]
TCHP OTVDMHSY Strong Biomarker [690]
TEAD1 OTK6971C Strong Altered Expression [239]
TFAM OTXXV5V7 Strong Biomarker [691]
TFR2 OTMYCCEO Strong Genetic Variation [692]
TGS1 OTM79LML Strong Biomarker [617]
TIMELESS OTD8DCBJ Strong Biomarker [385]
TIMM50 OTWJNUQL Strong Biomarker [693]
TIMM8A OTDX9687 Strong Genetic Variation [694]
TIMP4 OT8A68SW Strong Altered Expression [695]
TJP1 OTBDCUPK Strong Altered Expression [696]
TLX2 OTPFAUM8 Strong Biomarker [697]
TMBIM1 OTE47B57 Strong Altered Expression [698]
TMEM109 OTLUUDH1 Strong Altered Expression [699]
TMTC3 OTMTTDYG Strong Biomarker [461]
TOR1AIP1 OTTG8MAK Strong Biomarker [700]
TPI1 OT14KP4B Strong Biomarker [385]
TPM1 OTD73X6R Strong Genetic Variation [701]
TRAF2 OT1MEZZN Strong Genetic Variation [702]
TRIM32 OTJOV0PG Strong Biomarker [703]
TRIM72 OTFAFXPC Strong Biomarker [127]
ACAN OTUOCW8K Definitive Biomarker [704]
CASP12 OTY2W6FG Definitive Therapeutic [705]
ENDOG OT5IM7B3 Definitive Biomarker [706]
FKBP1B OT8CMPB2 Definitive Biomarker [707]
GRK1 OT7MPSG7 Definitive Biomarker [708]
MDH2 OT7364GY Definitive Biomarker [709]
MYOD1 OTV2S79X Definitive Therapeutic [710]
NPTXR OTQJEOIH Definitive Biomarker [120]
OGT OT1Z1ZXE Definitive Biomarker [711]
PLCD1 OT6WFVXZ Definitive Biomarker [712]
RAMP2 OTGQXLH5 Definitive Biomarker [713]
RNLS OTVP2WJM Definitive Biomarker [714]
TOMM70 OT8QBYZ0 Definitive Biomarker [715]
------------------------------------------------------------------------------------
⏷ Show the Full List of 488 DOT(s)

References

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22 The Cardioprotective Signaling Activity of Activated Protein C in Heart Failure and Ischemic Heart Diseases.Int J Mol Sci. 2019 Apr 10;20(7):1762. doi: 10.3390/ijms20071762.
23 Ginsenoside Rb3 regulates energy metabolism and apoptosis in cardiomyocytes via activating PPAR pathway.Biomed Pharmacother. 2019 Dec;120:109487. doi: 10.1016/j.biopha.2019.109487. Epub 2019 Sep 29.
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25 Neuregulin-1 Partially Improves Cardiac Function in Volume-Overload Heart Failure Through Regulation of Abnormal Calcium Handling.Front Pharmacol. 2019 Jun 21;10:616. doi: 10.3389/fphar.2019.00616. eCollection 2019.
26 Manifestations of and risk factors for acute myocardial injury after acute organophosphorus pesticide poisoning.Medicine (Baltimore). 2019 Feb;98(6):e14371. doi: 10.1097/MD.0000000000014371.
27 A novel urotensin II receptor antagonist, KR-36996, improved cardiac function and attenuated cardiac hypertrophy in experimental heart failure.Eur J Pharmacol. 2017 Mar 15;799:94-102. doi: 10.1016/j.ejphar.2017.02.003. Epub 2017 Feb 3.
28 Effects of a fully magnetically levitated centrifugal-flow or axial-flow left ventricular assist device on von Willebrand factor: A prospective multicenter clinical trial.J Heart Lung Transplant. 2019 Aug;38(8):806-816. doi: 10.1016/j.healun.2019.05.006. Epub 2019 May 17.
29 Dispelling dogma and misconceptions regarding the most pharmacologically targetable source of reactive species in inflammatory disease, xanthine oxidoreductase.Arch Toxicol. 2015 Aug;89(8):1193-207. doi: 10.1007/s00204-015-1523-8. Epub 2015 May 21.
30 Reversal of angiotensin-(1-12)-caused positive modulation on left ventricular contractile performance in heart failure: Assessment by pressure-volume analysis.Int J Cardiol. 2020 Feb 15;301:135-141. doi: 10.1016/j.ijcard.2019.09.004. Epub 2019 Sep 6.
31 Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis.Eur J Heart Fail. 2017 Apr;19(4):522-530. doi: 10.1002/ejhf.640. Epub 2016 Sep 19.
32 Diagnosis of genetic amyloidosis through the analysis of transthyretin gene mutation using high-resolution melting.Int J Cardiol. 2020 Feb 15;301:220-225. doi: 10.1016/j.ijcard.2019.10.028. Epub 2019 Oct 19.
33 Loss of VEGFB and its signaling in the diabetic heart is associated with increased cell death signaling.Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1163-H1175. doi: 10.1152/ajpheart.00659.2016. Epub 2017 Mar 17.
34 p38 MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes.Biochim Biophys Acta Mol Cell Res. 2019 Dec;1866(12):118557. doi: 10.1016/j.bbamcr.2019.118557. Epub 2019 Sep 7.
35 BMP10 preserves cardiac function through its dual activation of SMAD-mediated and STAT3-mediated pathways. J Biol Chem. 2019 Dec 27;294(52):19877-19888. doi: 10.1074/jbc.RA119.010943. Epub 2019 Nov 11.
36 From embryogenesis to adulthood: Critical role for GATA factors in heart development and function.IUBMB Life. 2020 Jan;72(1):53-67. doi: 10.1002/iub.2163. Epub 2019 Sep 13.
37 Protective role of heat shock transcription factor 1 in heart failure: A diagnostic approach.J Cell Physiol. 2019 Jun;234(6):7764-7770. doi: 10.1002/jcp.27639. Epub 2018 Oct 30.
38 ADAMTS16 activates latent TGF-, accentuating fibrosis and dysfunction of the pressure-overloaded heart.Cardiovasc Res. 2020 Apr 1;116(5):956-969. doi: 10.1093/cvr/cvz187.
39 Congenital myopathies are mainly associated with a mild cardiac phenotype.J Neurol. 2019 Jun;266(6):1367-1375. doi: 10.1007/s00415-019-09267-3. Epub 2019 Mar 14.
40 Pressure overload inhibits glucocorticoid receptor transcriptional activity in cardiomyocytes and promotes pathological cardiac hypertrophy.J Mol Cell Cardiol. 2019 May;130:122-130. doi: 10.1016/j.yjmcc.2019.03.019. Epub 2019 Apr 1.
41 P66Shc Deletion Ameliorates Oxidative Stress and Cardiac Dysfunction in Pressure Overload-Induced Heart Failure.J Card Fail. 2020 Mar;26(3):243-253. doi: 10.1016/j.cardfail.2019.09.003. Epub 2019 Sep 16.
42 Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans.Basic Res Cardiol. 2017 Dec 29;113(1):8. doi: 10.1007/s00395-017-0666-6. Print 2018 Jan 8.
43 Increased free Zn(2+) correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn(2+) -transporters in heart failure.J Cell Mol Med. 2018 Mar;22(3):1944-1956. doi: 10.1111/jcmm.13480. Epub 2018 Jan 15.
44 Emerging role of SIRT3 in mitochondrial dysfunction and cardiovascular diseases.Free Radic Res. 2019 Feb;53(2):139-149. doi: 10.1080/10715762.2018.1549732. Epub 2018 Dec 26.
45 Inhibition of AT1 receptors by losartan affects myocardial slow force response in healthy but not in monocrotaline-treated young rats.Gen Physiol Biophys. 2018 Mar;37(2):153-162. doi: 10.4149/gpb_2017025.
46 The mechanical effects of CRT promoting autophagy via mitochondrial calcium uniporter down-regulation and mitochondrial dynamics alteration.J Cell Mol Med. 2019 Jun;23(6):3833-3842. doi: 10.1111/jcmm.14227. Epub 2019 Apr 2.
47 Cardiomyocyte-specific loss of RNA polymerase II subunit 5-mediating protein causes myocardial dysfunction and heart failure.Cardiovasc Res. 2019 Sep 1;115(11):1617-1628. doi: 10.1093/cvr/cvy307.
48 ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating. Nat Genet. 2004 Apr;36(4):382-7. doi: 10.1038/ng1329. Epub 2004 Mar 21.
49 The apelinergic system: a perspective on challenges and opportunities in cardiovascular and metabolic disorders.Ann N Y Acad Sci. 2019 Nov;1455(1):12-33. doi: 10.1111/nyas.14123. Epub 2019 Jun 25.
50 Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. J Biol Chem. 2016 Feb 5;291(6):2583-600. doi: 10.1074/jbc.M115.702688. Epub 2015 Dec 15.
51 Albuminuria as a Predictor of Cardiovascular Outcomes in Patients With Acute Myocardial Infarction.J Am Heart Assoc. 2019 Apr 16;8(8):e010546. doi: 10.1161/JAHA.118.010546.
52 Reduced activin receptor-like kinase 1 activity promotes cardiac fibrosis in heart failure.Cardiovasc Pathol. 2017 Nov-Dec;31:26-33. doi: 10.1016/j.carpath.2017.07.004. Epub 2017 Jul 18.
53 Brain TACE (Tumor Necrosis Factor--Converting Enzyme) Contributes to Sympathetic Excitation in Heart Failure Rats.Hypertension. 2019 Jul;74(1):63-72. doi: 10.1161/HYPERTENSIONAHA.119.12651. Epub 2019 Jun 3.
54 Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptor 1 (PAC1) in the human infant brain and changes in the Sudden Infant Death Syndrome (SIDS).Neurobiol Dis. 2017 Jul;103:70-77. doi: 10.1016/j.nbd.2017.04.002. Epub 2017 Apr 6.
55 Biomarkers of Inflammation, Fibrosis, and Acute Kidney Injury in Patients with Heart Failure with and without Left Ventricular Assist Device Implantation.Cardiorenal Med. 2019;9(2):108-116. doi: 10.1159/000494090. Epub 2019 Jan 30.
56 Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failure.Mol Med Rep. 2017 Aug;16(2):1723-1730. doi: 10.3892/mmr.2017.6776. Epub 2017 Jun 14.
57 Alterations in cardiac DNA methylation in human dilated cardiomyopathy.EMBO Mol Med. 2013 Mar;5(3):413-29. doi: 10.1002/emmm.201201553. Epub 2013 Jan 22.
58 Cardioprotective role of APIP in myocardial infarction through ADORA2B.Cell Death Dis. 2019 Jul 1;10(7):511. doi: 10.1038/s41419-019-1746-3.
59 Heart failure leads to altered 2-adrenoceptor/cyclic adenosine monophosphate dynamics in the sarcolemmal phospholemman/Na,K ATPase microdomain.Cardiovasc Res. 2019 Mar 1;115(3):546-555. doi: 10.1093/cvr/cvy221.
60 The first-in-man randomized trial of a beta3 adrenoceptor agonist in chronic heart failure: the BEAT-HF trial.Eur J Heart Fail. 2017 Apr;19(4):566-575. doi: 10.1002/ejhf.714. Epub 2016 Dec 18.
61 Anti-1-Adrenoreceptor auto-Antibodies in elderly heart failure patients.Front Biosci (Landmark Ed). 2019 Mar 1;24(6):1037-1049. doi: 10.2741/4766.
62 Mediators of the Effects of Canagliflozin on HeartFailure in Patients With Type 2 Diabetes.JACC Heart Fail. 2020 Jan;8(1):57-66. doi: 10.1016/j.jchf.2019.08.004. Epub 2019 Oct 29.
63 Acetaldehyde dehydrogenase 2 deficiency exacerbates cardiac fibrosis by promoting mobilization and homing of bone marrow fibroblast progenitor cells.J Mol Cell Cardiol. 2019 Dec;137:107-118. doi: 10.1016/j.yjmcc.2019.10.006. Epub 2019 Oct 24.
64 Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner.PLoS One. 2018 Aug 23;13(8):e0202693. doi: 10.1371/journal.pone.0202693. eCollection 2018.
65 Targeted therapy of underlying conditions improves quality of life in patients with persistent atrial fibrillation: results of the RACE 3 study.Europace. 2019 Apr 1;21(4):563-571. doi: 10.1093/europace/euy311.
66 Sacubitril/Valsartan: Updates and Clinical Evidence for a Disease-Modifying Approach.Drugs. 2019 Sep;79(14):1543-1556. doi: 10.1007/s40265-019-01181-2.
67 Annexin A5 in treated hypertensive patients and its association with target organ damage.J Hypertens. 2017 Jan;35(1):154-161. doi: 10.1097/HJH.0000000000001143.
68 C-reactive protein in heart failure: prognostic value and the effect of valsartan. Circulation. 2005 Sep 6;112(10):1428-34. doi: 10.1161/CIRCULATIONAHA.104.508465. Epub 2005 Aug 29.
69 Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels.J Am Coll Cardiol. 2011 Jan 18;57(3):356-65. doi: 10.1016/j.jacc.2010.08.635.
70 -Arrestin 2 mediates arginine vasopressin-induced IL-6 induction via the ERK(1/2)-NF-B signal pathway in murine hearts.Acta Pharmacol Sin. 2020 Feb;41(2):198-207. doi: 10.1038/s41401-019-0292-y. Epub 2019 Sep 12.
71 Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling.Circulation. 2018 Jun 5;137(23):2497-2513. doi: 10.1161/CIRCULATIONAHA.117.030353. Epub 2018 Jan 25.
72 The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.Sci Signal. 2018 Feb 6;11(516):eaan3638. doi: 10.1126/scisignal.aan3638.
73 The influence of post-infarct heart failure and high fat diet on the expression of apelin APJ and vasopressin V1a and V1b receptors.Neuropeptides. 2019 Dec;78:101975. doi: 10.1016/j.npep.2019.101975. Epub 2019 Oct 15.
74 Utilization and budget impact of tolvaptan in the inpatient setting among patients with heart failure and hyponatremia.Curr Med Res Opin. 2018 Mar;34(3):559-566. doi: 10.1080/03007995.2018.1423958. Epub 2018 Jan 22.
75 Axl expression is increased in early stages of left ventricular remodeling in an animal model with pressure-overload.PLoS One. 2019 Jun 10;14(6):e0217926. doi: 10.1371/journal.pone.0217926. eCollection 2019.
76 Increased BACE1-AS long noncoding RNA and -amyloid levels in heart failure.Cardiovasc Res. 2017 Apr 1;113(5):453-463. doi: 10.1093/cvr/cvx013.
77 Shenfu Formula reduces cardiomyocyte apoptosis in heart failure rats by regulating microRNAs.J Ethnopharmacol. 2018 Dec 5;227:105-112. doi: 10.1016/j.jep.2018.05.006. Epub 2018 May 8.
78 Global secretome analysis of resident cardiac progenitor cells from wild-type and transgenic heart failure mice: Why ambience matters.J Cell Physiol. 2019 Jul;234(7):10111-10122. doi: 10.1002/jcp.27677. Epub 2018 Dec 21.
79 Randomised placebo-controlled safety and tolerability trial of FK506 (tacrolimus) for pulmonary arterial hypertension.Eur Respir J. 2017 Sep 11;50(3):1602449. doi: 10.1183/13993003.02449-2016. Print 2017 Sep.
80 Relationship between the autoantibody and expression of 3-adrenoceptor in lung and heart.PLoS One. 2013 Jul 5;8(7):e68747. doi: 10.1371/journal.pone.0068747. Print 2013.
81 Myocardial expression of the anaphylatoxin receptor C3aR is associated with cardiac inflammation and prognosis in patients with non-ischaemic heart failure.ESC Heart Fail. 2018 Oct;5(5):846-857. doi: 10.1002/ehf2.12298. Epub 2018 Aug 31.
82 Transgenic expression of carbonic anhydrase III in cardiac muscle demonstrates a mechanism to tolerate acidosis.Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C922-C931. doi: 10.1152/ajpcell.00130.2019. Epub 2019 Aug 7.
83 Genetics of heart rate in heart failure patients (GenHRate).Hum Genomics. 2019 May 21;13(1):22. doi: 10.1186/s40246-019-0206-6.
84 Lipid-Lowering Agents in Older Individuals: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.J Clin Endocrinol Metab. 2019 May 1;104(5):1585-1594. doi: 10.1210/jc.2019-00195.
85 Cardiac resynchronization therapy with His bundle pacing as a method of treatment of chronic heart failure in patients with permanent atrial fibrillation and left bundle branch block.J Electrocardiol. 2018 May-Jun;51(3):405-408. doi: 10.1016/j.jelectrocard.2018.02.014. Epub 2018 Mar 2.
86 Increased calpain-1 in mitochondria induces dilated heart failure in mice: role of mitochondrial superoxide anion.Basic Res Cardiol. 2019 Mar 15;114(3):17. doi: 10.1007/s00395-019-0726-1.
87 Cardioprotective effect of the secretome of Sca-1+ and Sca-1- cells in heart failure: not equal, but equally important?.Cardiovasc Res. 2020 Mar 1;116(3):566-575. doi: 10.1093/cvr/cvz140.
88 Homeostatic Chemokines and Prognosisin Patients With Acute Coronary Syndromes.J Am Coll Cardiol. 2019 Aug 13;74(6):774-782. doi: 10.1016/j.jacc.2019.06.030.
89 Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes.Circ Heart Fail. 2019 Mar;12(3):e005765. doi: 10.1161/CIRCHEARTFAILURE.118.005765.
90 Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart.Circ Res. 2019 Mar 15;124(6):881-890. doi: 10.1161/CIRCRESAHA.118.314030.
91 Enhancing fatty acid utilization ameliorates mitochondrial fragmentation and cardiac dysfunction via rebalancing optic atrophy 1 processing in the failing heart.Cardiovasc Res. 2018 Jun 1;114(7):979-991. doi: 10.1093/cvr/cvy052.
92 Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure.JCI Insight. 2017 Aug 3;2(15):e92476. doi: 10.1172/jci.insight.92476. eCollection 2017 Aug 3.
93 TAK-272 (imarikiren), a novel renin inhibitor, improves cardiac remodeling and mortality in a murine heart failure model.PLoS One. 2018 Aug 9;13(8):e0202176. doi: 10.1371/journal.pone.0202176. eCollection 2018.
94 Cholesteryl ester transfer protein (CETP), HDL capacity of receiving cholesterol and status of inflammatory cytokines in patients with severe heart failure.Lipids Health Dis. 2018 Oct 20;17(1):242. doi: 10.1186/s12944-018-0888-0.
95 The alternative complement pathway is dysregulated in patients with chronic heart failure.Sci Rep. 2017 Feb 14;7:42532. doi: 10.1038/srep42532.
96 Regulation of circulating chromogranin B levels in heart failure.Biomarkers. 2018 Feb;23(1):78-87. doi: 10.1080/1354750X.2017.1395079. Epub 2017 Nov 7.
97 Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor.Eur J Med Chem. 2018 Sep 5;157:1500-1511. doi: 10.1016/j.ejmech.2018.08.062. Epub 2018 Aug 23.
98 The ClC-3 chloride channels in cardiovascular disease.Acta Pharmacol Sin. 2011 Jun;32(6):675-84. doi: 10.1038/aps.2011.30. Epub 2011 May 23.
99 Loss-of-function DNA sequence variant in the CLCNKA chloride channel implicates the cardio-renal axis in interindividual heart failure risk variation.Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2456-61. doi: 10.1073/pnas.1017494108. Epub 2011 Jan 19.
100 Cardiac natriuretic peptides: from basic discovery to clinical practice.Cardiovasc Ther. 2011 Dec;29(6):362-76. doi: 10.1111/j.1755-5922.2010.00152.x. Epub 2010 Apr 23.
101 Right Ventricular and Pulmonary Vascular Function are Influenced by Age and Volume Expansion in Healthy Humans.J Card Fail. 2019 Jan;25(1):51-59. doi: 10.1016/j.cardfail.2018.11.013. Epub 2018 Nov 22.
102 Cardiac CRFR1 Expression Is Elevated in Human Heart Failure and Modulated by Genetic Variation and Alternative Splicing.Endocrinology. 2016 Dec;157(12):4865-4874. doi: 10.1210/en.2016-1448. Epub 2016 Oct 18.
103 Corticotropin-Releasing Hormone Family and Their Receptors in the Cardiovascular System.Circ J. 2019 Jan 25;83(2):261-266. doi: 10.1253/circj.CJ-18-0428. Epub 2018 Dec 22.
104 Chronic interval exercise training prevents BK(Ca) channel-mediated coronary vascular dysfunction in aortic-banded miniswine.J Appl Physiol (1985). 2018 Jul 1;125(1):86-96. doi: 10.1152/japplphysiol.01138.2017. Epub 2018 Mar 29.
105 Psychometric Validation of the Mandarin Version Control Attitudes Scale-Revised Questionnaire in Taiwanese Patients With Heart Failure.J Cardiovasc Nurs. 2018 Mar/Apr;33(2):187-194. doi: 10.1097/JCN.0000000000000431.
106 Hydrocephalus-induced neurogenic stunned myocardium and cardiac arrest in a child: completely reversed with CSF diversion.J Neurosurg Pediatr. 2019 Apr 19;24(1):35-40. doi: 10.3171/2019.2.PEDS18711.
107 Combined therapy with cardioprotective cytokine administration and antiapoptotic gene transfer in postinfarction heart failure.Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H616-26. doi: 10.1152/ajpheart.01147.2008. Epub 2009 Jan 16.
108 CT-1 (Cardiotrophin-1)-Gal-3 (Galectin-3) Axis in Cardiac Fibrosis and Inflammation.Hypertension. 2019 Mar;73(3):602-611. doi: 10.1161/HYPERTENSIONAHA.118.11874.
109 Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca(2+)/calmodulin-dependent protein kinase II.Redox Biol. 2018 Oct;19:250-262. doi: 10.1016/j.redox.2018.08.008. Epub 2018 Aug 22.
110 Molecular network, pathway, and functional analysis of time-dependent gene changes related to cathepsin G exposure in neonatal rat cardiomyocytes.Gene. 2018 Sep 10;671:58-66. doi: 10.1016/j.gene.2018.05.110. Epub 2018 May 31.
111 The cardiovascular actions of fractalkine/CX3CL1 in the hypothalamic paraventricular nucleus are attenuated in rats with heart failure.Exp Physiol. 2014 Jan;99(1):111-22. doi: 10.1113/expphysiol.2013.075432. Epub 2013 Sep 13.
112 Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.J Toxicol Environ Health A. 2012;75(4):213-31. doi: 10.1080/15287394.2012.652055.
113 Early administration of empagliflozin preserved heart function in cardiorenal syndrome in rat.Biomed Pharmacother. 2019 Jan;109:658-670. doi: 10.1016/j.biopha.2018.10.095. Epub 2018 Nov 4.
114 Imidazopyridyl compounds as aldosterone synthase inhibitors.Bioorg Med Chem Lett. 2017 Jan 15;27(2):143-146. doi: 10.1016/j.bmcl.2016.12.003. Epub 2016 Dec 2.
115 CYP2D6 Genetic Variation and Beta-Blocker Maintenance Dose in Patients with Heart Failure.Pharm Res. 2017 Aug;34(8):1615-1625. doi: 10.1007/s11095-017-2104-8. Epub 2017 Feb 8.
116 Endothelium-specific CYP2J2 overexpression improves cardiac dysfunction by promoting angiogenesis via Jagged1/Notch1 signaling.J Mol Cell Cardiol. 2018 Oct;123:118-127. doi: 10.1016/j.yjmcc.2018.08.027. Epub 2018 Sep 13.
117 Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress.Am J Physiol Heart Circ Physiol. 2019 Sep 1;317(3):H617-H626. doi: 10.1152/ajpheart.00177.2019. Epub 2019 Jul 12.
118 Effects of zamicastat treatment in a genetic model of salt-sensitive hypertension and heart failure.Eur J Pharmacol. 2019 Jan 5;842:125-132. doi: 10.1016/j.ejphar.2018.10.030. Epub 2018 Oct 26.
119 Redd1 protects against postinfarction cardiac dysfunction by targeting apoptosis and autophagy.Int J Mol Med. 2019 Dec;44(6):2065-2076. doi: 10.3892/ijmm.2019.4366. Epub 2019 Oct 4.
120 Regulation of neuronal type genes in congestive heart failure rats.Acta Physiol (Oxf). 2006 Jan;186(1):17-27. doi: 10.1111/j.1748-1716.2005.01503.x.
121 Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure.J Biol Chem. 2014 Oct 24;289(43):29881-91. doi: 10.1074/jbc.M114.601864. Epub 2014 Aug 25.
122 The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy.Cardiovasc Res. 2018 Sep 1;114(11):1474-1486. doi: 10.1093/cvr/cvy091.
123 Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis.Circ Res. 2009 Apr 10;104(7):896-904. doi: 10.1161/CIRCRESAHA.108.172882. Epub 2009 Feb 26.
124 Dynamin-2 mediates heart failure by modulating Ca2+ -dependent cardiomyocyte apoptosis.Int J Cardiol. 2013 Oct 3;168(3):2109-19. doi: 10.1016/j.ijcard.2013.01.006. Epub 2013 Feb 11.
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130 Bone Morphogenetic Protein 9 Reduces Cardiac Fibrosis and Improves Cardiac Function in Heart Failure.Circulation. 2018 Jul 31;138(5):513-526. doi: 10.1161/CIRCULATIONAHA.117.031635.
131 Specific Inhibition of Brain Angiotensin III Formation as a New Strategy for Prevention of Heart Failure After Myocardial Infarction.J Cardiovasc Pharmacol. 2019 Feb;73(2):82-91. doi: 10.1097/FJC.0000000000000638.
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137 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.Front Genet. 2016 Oct 13;7:179. doi: 10.3389/fgene.2016.00179. eCollection 2016.
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141 Fibroblast Growth Factor 23 Genotype and Cardiovascular Disease in Patients Undergoing Hemodialysis.Am J Nephrol. 2019;49(2):125-132. doi: 10.1159/000496060. Epub 2019 Jan 22.
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144 Activin type II receptor signaling in cardiac aging and heart failure.Sci Transl Med. 2019 Mar 6;11(482):eaau8680. doi: 10.1126/scitranslmed.aau8680.
145 FTO-Dependent N(6)-Methyladenosine Regulates Cardiac Function During Remodeling and Repair.Circulation. 2019 Jan 22;139(4):518-532. doi: 10.1161/CIRCULATIONAHA.118.033794.
146 Optimising pacemaker therapy and medical therapy in pacemaker patients for heart failure: protocol for the OPT-PACE randomised controlled trial.BMJ Open. 2019 Jul 17;9(7):e028613. doi: 10.1136/bmjopen-2018-028613.
147 Role of sympathetic cotransmitter galanin on autonomic balance in heart failure: an active player or a bystander?.Anatol J Cardiol. 2017 Oct;18(4):281-288. doi: 10.14744/AnatolJCardiol.2017.7831. Epub 2017 Aug 11.
148 Serum levels of Growth Arrest-Specific 6 protein and soluble AXL in patients with ST-segment elevation myocardial infarction.Eur Heart J Acute Cardiovasc Care. 2019 Dec;8(8):708-716. doi: 10.1177/2048872617740833. Epub 2017 Nov 9.
149 Exercise training induces eNOS coupling and restores relaxation in coronary arteries of heart failure rats.Am J Physiol Heart Circ Physiol. 2018 Apr 1;314(4):H878-H887. doi: 10.1152/ajpheart.00624.2017. Epub 2018 Jan 5.
150 Combined effects of growth hormone and testosterone replacement treatment in heart failure.ESC Heart Fail. 2019 Dec;6(6):1216-1221. doi: 10.1002/ehf2.12520. Epub 2019 Nov 7.
151 Ghrelin improves disturbed myocardial energy metabolism in rats with heart failure induced by isoproterenol.J Pept Sci. 2010 Aug;16(8):392-402. doi: 10.1002/psc.1253.
152 Immuno-Spin Trapping-Based Detection of Oxidative Modifications in Cardiomyocytes and Coronary Endothelium in the Progression of Heart Failure in Tgq*44 Mice.Front Immunol. 2018 May 7;9:938. doi: 10.3389/fimmu.2018.00938. eCollection 2018.
153 Association of Oxidative Stress and Platelet Receptor Glycoprotein GPIb and GPVI Shedding During Nonsurgical Bleeding in Heart Failure Patients With Continuous-Flow Left Ventricular Assist Device Support.ASAIO J. 2018 Jul/Aug;64(4):462-471. doi: 10.1097/MAT.0000000000000680.
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156 The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice.Am J Hypertens. 2018 Aug 3;31(9):1049-1058. doi: 10.1093/ajh/hpy073.
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162 PI3K-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.Nat Commun. 2018 Dec 19;9(1):5390. doi: 10.1038/s41467-018-07812-8.
163 Association of Abnormal Left Ventricular Functional Reserve With Outcome in Heart Failure With Preserved Ejection Fraction.JACC Cardiovasc Imaging. 2018 Dec;11(12):1737-1746. doi: 10.1016/j.jcmg.2017.07.028. Epub 2017 Nov 15.
164 Periodontitis and bone metabolism in patients with advanced heart failure and after heart transplantation.ESC Heart Fail. 2017 May;4(2):169-177. doi: 10.1002/ehf2.12126. Epub 2017 Mar 1.
165 Discovery of novel small molecule TLR4 inhibitors as potent anti-inflammatory agents.Eur J Med Chem. 2018 Jun 25;154:253-266. doi: 10.1016/j.ejmech.2018.05.033. Epub 2018 May 22.
166 O-GlcNAcylation of Histone Deacetylase 4 Protects the Diabetic Heart From Failure.Circulation. 2019 Aug 13;140(7):580-594. doi: 10.1161/CIRCULATIONAHA.117.031942. Epub 2019 Jun 14.
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168 Aggravated myocardial infarction-induced cardiac remodeling and heart failure in histamine-deficient mice.Sci Rep. 2017 Mar 8;7:44007. doi: 10.1038/srep44007.
169 mAKAP signalosomes - A nodal regulator of gene transcription associated with pathological cardiac remodeling.Cell Signal. 2019 Nov;63:109357. doi: 10.1016/j.cellsig.2019.109357. Epub 2019 Jul 9.
170 Cardiomyocyte Homeodomain-Interacting Protein Kinase 2 Maintains Basal Cardiac Function via Extracellular Signal-Regulated Kinase Signaling.Circulation. 2019 Nov 26;140(22):1820-1833. doi: 10.1161/CIRCULATIONAHA.119.040740. Epub 2019 Oct 4.
171 Emergence of Members of TRAF and DUB of Ubiquitin Proteasome System in the Regulation of Hypertrophic Cardiomyopathy.Front Genet. 2018 Aug 21;9:336. doi: 10.3389/fgene.2018.00336. eCollection 2018.
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175 Shenfu Injection suppresses inflammation by targeting haptoglobin and pentraxin 3 in rats with chronic ischemic heart failure.Chin J Integr Med. 2015 Jan;21(1):22-8. doi: 10.1007/s11655-013-1440-8. Epub 2013 Mar 15.
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180 Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle.J Mol Cell Cardiol. 2007 Dec;43(6):767-79. doi: 10.1016/j.yjmcc.2007.08.019. Epub 2007 Sep 5.
181 Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.Circ Res. 2009 Jan 2;104(1):113-23. doi: 10.1161/CIRCRESAHA.108.180976. Epub 2008 Nov 20.
182 Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study.Am Heart J. 2007 Jan;153(1):54-8. doi: 10.1016/j.ahj.2006.10.019.
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185 New Role for Interleukin-13 Receptor 1 in Myocardial Homeostasis and Heart Failure.J Am Heart Assoc. 2017 May 20;6(5):e005108. doi: 10.1161/JAHA.116.005108.
186 Soluble ST2 promotes oxidative stress and inflammation in cardiac fibroblasts: an in vitro and in vivo study in aortic stenosis.Clin Sci (Lond). 2019 Jul 17;133(14):1537-1548. doi: 10.1042/CS20190475. Print 2019 Jul 31.
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193 Calcineurin-NFATc regulates type 2 inositol 1,4,5-trisphosphate receptor (InsP3R2) expression during cardiac remodeling.J Biol Chem. 2014 Feb 28;289(9):6188-98. doi: 10.1074/jbc.M113.495242. Epub 2014 Jan 10.
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195 Long Noncoding RNA Kcna2 Antisense RNA Contributes to Ventricular Arrhythmias via Silencing Kcna2 in Rats With Congestive Heart Failure.J Am Heart Assoc. 2017 Dec 20;6(12):e005965. doi: 10.1161/JAHA.117.005965.
196 Analysis of the arrhythmogenic substrate in human heart failure.Cardiovasc Pathol. 2013 Mar-Apr;22(2):133-40. doi: 10.1016/j.carpath.2012.07.003. Epub 2012 Oct 1.
197 Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure.BMC Pharmacol Toxicol. 2019 Mar 6;20(1):16. doi: 10.1186/s40360-019-0294-x.
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206 Functions for the cardiomyokine, MANF, in cardioprotection, hypertrophy and heart failure.J Mol Cell Cardiol. 2011 Oct;51(4):512-7. doi: 10.1016/j.yjmcc.2010.10.008. Epub 2010 Oct 21.
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211 Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure.ACS Med Chem Lett. 2017 Feb 8;8(3):316-320. doi: 10.1021/acsmedchemlett.6b00481. eCollection 2017 Mar 9.
212 The protective effect of kaempferol on heart via the regulation of Nrf2, NF-, and PI3K/Akt/GSK-3 signaling pathways in isoproterenol-induced heart failure in diabetic rats.Drug Dev Res. 2019 May;80(3):294-309. doi: 10.1002/ddr.21495. Epub 2019 Mar 12.
213 Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy.Elife. 2017 Aug 22;6:e28118. doi: 10.7554/eLife.28118.
214 Reduced hybrid/complex N-glycosylation disrupts cardiac electrical signaling and calcium handling in a model of dilated cardiomyopathy.J Mol Cell Cardiol. 2019 Jul;132:13-23. doi: 10.1016/j.yjmcc.2019.05.001. Epub 2019 May 6.
215 Migrated T lymphocytes into malignant pleural effusions: an indicator of good prognosis in lung adenocarcinoma patients.Sci Rep. 2019 Feb 28;9(1):2996. doi: 10.1038/s41598-018-35840-3.
216 Predictive value of serum myostatin for the severity and clinical outcome of heart failure.Eur J Intern Med. 2019 Jun;64:33-40. doi: 10.1016/j.ejim.2019.04.017. Epub 2019 May 2.
217 Identification of cellular targets involved in cardiac failure caused by PKI in oncology: an approach combining pharmacovigilance and pharmacodynamics.Br J Clin Pharmacol. 2017 Jul;83(7):1544-1555. doi: 10.1111/bcp.13238. Epub 2017 Feb 14.
218 Carbohydrate antigen 125 in heart failure. New era in the monitoring and control of treatment.Med Clin (Barc). 2019 Apr 5;152(7):266-273. doi: 10.1016/j.medcli.2018.08.020. Epub 2018 Nov 12.
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220 Evaluations of the effect of HuangQi against heart failure based on comprehensive echocardiography index and metabonomics.Phytomedicine. 2018 Nov 15;50:205-212. doi: 10.1016/j.phymed.2018.04.027. Epub 2018 Apr 10.
221 TGF-1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.J Mol Cell Cardiol. 2017 Nov;112:49-57. doi: 10.1016/j.yjmcc.2017.08.015. Epub 2017 Sep 1.
222 Loss of p47phox subunit enhances susceptibility to biomechanical stress and heart failure because of dysregulation of cortactin and actin filaments.Circ Res. 2013 Jun 7;112(12):1542-56. doi: 10.1161/CIRCRESAHA.111.300299. Epub 2013 Apr 3.
223 Effects of sulforaphane in the central nervous system.Eur J Pharmacol. 2019 Jun 15;853:153-168. doi: 10.1016/j.ejphar.2019.03.010. Epub 2019 Mar 8.
224 Imidazoline receptors in the heart: characterization, distribution, and regulation.J Cardiovasc Pharmacol. 2002 Jun;39(6):875-83. doi: 10.1097/00005344-200206000-00013.
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227 Eplerenone mimics features of the alternative activation in macrophages obtained from patients with heart failure and healthy volunteers.Eur J Pharmacol. 2014 Mar 5;726:96-108. doi: 10.1016/j.ejphar.2014.01.043.
228 NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase.Antioxid Redox Signal. 2019 Jul 1;31(1):39-58. doi: 10.1089/ars.2018.7548. Epub 2018 Dec 28.
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232 Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis.Cardiovasc Res. 2018 Oct 1;114(12):1617-1628. doi: 10.1093/cvr/cvy125.
233 Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts.Cardiovasc Res. 2004 Jan 1;61(1):87-93. doi: 10.1016/j.cardiores.2003.11.005.
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235 Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.Sci Rep. 2019 May 1;9(1):6801. doi: 10.1038/s41598-019-42592-1.
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259 Heart Failure Stimulates Tumor Growth by Circulating Factors.Circulation. 2018 Aug 14;138(7):678-691. doi: 10.1161/CIRCULATIONAHA.117.030816.
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279 Clinical Impact of ABO and Rhesus D Blood Type Groups in Patients With Chronic Heart Failure.Am J Cardiol. 2018 Aug 1;122(3):413-419. doi: 10.1016/j.amjcard.2018.04.018. Epub 2018 May 2.
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287 Chagas disease is associated with a worse prognosis at 1-year follow-up after implantable cardioverter-defibrillator for secondary prevention in heart failure patients.J Cardiovasc Electrophysiol. 2019 Nov;30(11):2448-2452. doi: 10.1111/jce.14164. Epub 2019 Sep 18.
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290 Correction: Increased Levels of Plasma Soluble Sema4D in Patients with Heart Failure.PLoS One. 2019 Mar 28;14(3):e0214894. doi: 10.1371/journal.pone.0214894. eCollection 2019.
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292 Serum-glucocorticoid-regulated kinase 1 contributes to mechanical stretch-induced inflammatory responses in cardiac fibroblasts.Mol Cell Biochem. 2018 Aug;445(1-2):67-78. doi: 10.1007/s11010-017-3252-1. Epub 2017 Dec 14.
293 Protective mechanism of SIRT1 on Hcy-induced atrial fibrosis mediated by TRPC3.J Cell Mol Med. 2020 Jan;24(1):488-510. doi: 10.1111/jcmm.14757. Epub 2019 Nov 4.
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295 Cardiac acetylcholine inhibits ventricular remodeling and dysfunction under pathologic conditions.FASEB J. 2016 Feb;30(2):688-701. doi: 10.1096/fj.15-277046. Epub 2015 Oct 19.
296 Pretreatment with KGA-2727, a selective SGLT1 inhibitor, is protective against myocardial infarction-induced ventricular remodeling and heart failure in mice.J Pharmacol Sci. 2020 Jan;142(1):16-25. doi: 10.1016/j.jphs.2019.11.001. Epub 2019 Nov 7.
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298 Characterizing Vascular Dysfunction in Genetically Modified Mice through the Hyperoxia Model.Int J Mol Sci. 2019 May 2;20(9):2178. doi: 10.3390/ijms20092178.
299 The role of splanchnic congestion and the intestinal microenvironment in the pathogenesis of advanced heart failure.Curr Opin Support Palliat Care. 2019 Mar;13(1):24-30. doi: 10.1097/SPC.0000000000000414.
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301 Small-hairpin RNA and pharmacological targeting of neutral sphingomyelinase prevent diaphragm weakness in rats with heart failure and reduced ejection fraction.Am J Physiol Lung Cell Mol Physiol. 2019 Apr 1;316(4):L679-L690. doi: 10.1152/ajplung.00516.2018. Epub 2019 Jan 31.
302 Homozygous damaging SOD2 variant causes lethal neonatal dilated cardiomyopathy.J Med Genet. 2020 Jan;57(1):23-30. doi: 10.1136/jmedgenet-2019-106330. Epub 2019 Sep 7.
303 Dysfunction in the II spectrin-dependent cytoskeleton underlies human arrhythmia.Circulation. 2015 Feb 24;131(8):695-708. doi: 10.1161/CIRCULATIONAHA.114.013708. Epub 2015 Jan 28.
304 Identification of Potential Gene Interactions in Heart Failure Caused by Idiopathic Dilated Cardiomyopathy.Med Sci Monit. 2018 Oct 28;24:7697-7709. doi: 10.12659/MSM.912984.
305 Stanniocalcin-1 is a naturally occurring L-channel inhibitor in cardiomyocytes: relevance to human heart failure.Am J Physiol Heart Circ Physiol. 2003 Jul;285(1):H442-8. doi: 10.1152/ajpheart.01071.2002. Epub 2003 Mar 27.
306 Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction. Cardiovasc Diabetol. 2018 Apr 30;17(1):63.
307 A systematic review of large scale and heterogeneous gene array data in heart failure.J Mol Cell Cardiol. 2005 Mar;38(3):425-32. doi: 10.1016/j.yjmcc.2004.12.016.
308 Plasma Ceramides and Sphingomyelins in Relation to Heart Failure Risk.Circ Heart Fail. 2019 Jul;12(7):e005708. doi: 10.1161/CIRCHEARTFAILURE.118.005708. Epub 2019 Jul 12.
309 Genomic profiling reveals the potential role of TCL1A and MDR1 deficiency in chemotherapy-induced cardiotoxicity.Int J Biol Sci. 2013 Apr 22;9(4):350-60. doi: 10.7150/ijbs.6058. Print 2013.
310 Telomere attrition and Chk2 activation in human heart failure.Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5378-83. doi: 10.1073/pnas.0836098100. Epub 2003 Apr 17.
311 Impact of Renal Denervation on Atrial Arrhythmogenic Substrate in Ischemic Model of Heart Failure.J Am Heart Assoc. 2018 Jan 22;7(2):e007312. doi: 10.1161/JAHA.117.007312.
312 Tissue thyroid hormones and thyronamines.Heart Fail Rev. 2016 Jul;21(4):373-90. doi: 10.1007/s10741-016-9553-8.
313 The long noncoding RNA XIST regulates cardiac hypertrophy by targeting miR-101.J Cell Physiol. 2019 Aug;234(8):13680-13692. doi: 10.1002/jcp.28047. Epub 2019 Jan 3.
314 Thymosin Beta-4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction.J Am Heart Assoc. 2017 Jun 13;6(6):e005586. doi: 10.1161/JAHA.117.005586.
315 TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart.J Mol Cell Cardiol. 2018 Aug;121:107-123. doi: 10.1016/j.yjmcc.2018.07.003. Epub 2018 Jul 5.
316 Dysfunctional and Proinflammatory Regulatory T-Lymphocytes Are Essential for Adverse Cardiac Remodeling in Ischemic Cardiomyopathy.Circulation. 2019 Jan 8;139(2):206-221. doi: 10.1161/CIRCULATIONAHA.118.036065.
317 Potential of the Cardiovascular Drug Levosimendan in the Management of Amyotrophic Lateral Sclerosis: An Overview of a Working Hypothesis.J Cardiovasc Pharmacol. 2019 Nov;74(5):389-399. doi: 10.1097/FJC.0000000000000728.
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319 Identification of the molecular basis of doxorubicin-induced cardiotoxicity.Nat Med. 2012 Nov;18(11):1639-42. doi: 10.1038/nm.2919. Epub 2012 Oct 28.
320 Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure.Int J Cardiol. 2019 Mar 15;279:141-144. doi: 10.1016/j.ijcard.2018.12.076. Epub 2018 Dec 28.
321 Inhibition of TRPC1 prevents cardiac hypertrophy via NF-B signaling pathway in human pluripotent stem cell-derived cardiomyocytes.J Mol Cell Cardiol. 2019 Jan;126:143-154. doi: 10.1016/j.yjmcc.2018.10.020. Epub 2018 Nov 10.
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324 Resiniferatoxin reduces ventricular arrhythmias in heart failure via selectively blunting cardiac sympathetic afferent projection into spinal cord in rats.Eur J Pharmacol. 2020 Jan 15;867:172836. doi: 10.1016/j.ejphar.2019.172836. Epub 2019 Dec 4.
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327 Rodent heart failure models do not reflect the human circulating microRNA signature in heart failure.PLoS One. 2017 May 5;12(5):e0177242. doi: 10.1371/journal.pone.0177242. eCollection 2017.
328 Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure.Int J Med Sci. 2017 Jul 20;14(9):891-895. doi: 10.7150/ijms.19854. eCollection 2017.
329 UCP3 Ablation Exacerbates High-Salt Induced Cardiac Hypertrophy and Cardiac Dysfunction.Cell Physiol Biochem. 2018;46(4):1683-1692. doi: 10.1159/000489244. Epub 2018 Apr 20.
330 Correction: Tongxinluo protects against pressure overload-induced heart failure in mice involving VEGF/Akt/eNOS pathway activation.PLoS One. 2019 Aug 1;14(8):e0220845. doi: 10.1371/journal.pone.0220845. eCollection 2019.
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345 Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation.Cancer Chemother Pharmacol. 2011 Jun;67(6):1381-8. doi: 10.1007/s00280-010-1441-7. Epub 2010 Aug 31.
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350 Paradoxical Effects of Sodium-Calcium Exchanger Inhibition on Torsade de Pointes and Early Afterdepolarization in a Heart Failure Rabbit Model.J Cardiovasc Pharmacol. 2018 Aug;72(2):97-105. doi: 10.1097/FJC.0000000000000598.
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356 Association Between Plasma Neutrophil Gelatinase-Associated Lipocalin and Cardiac Disease Hospitalizations and Deaths in Older Women.J Am Heart Assoc. 2019 Jan 8;8(1):e011028. doi: 10.1161/JAHA.118.011028.
357 Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study.PLoS One. 2018 Dec 17;13(12):e0208042. doi: 10.1371/journal.pone.0208042. eCollection 2018.
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370 Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats.J Clin Invest. 2008 Mar;118(3):975-83. doi: 10.1172/JCI32824.
371 Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients with myoadenylate deaminase deficiency.PLoS One. 2017 Nov 2;12(11):e0187266. doi: 10.1371/journal.pone.0187266. eCollection 2017.
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504 Circulating miR-148b-3p and miR-409-3p as biomarkers for heart failure in patients with mitral regurgitation.Int J Cardiol. 2016 Nov 1;222:148-154. doi: 10.1016/j.ijcard.2016.07.179. Epub 2016 Jul 29.
505 The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure.J Intern Med. 2014 Jun;275(6):621-30. doi: 10.1111/joim.12175. Epub 2014 Jan 9.
506 Follistatin-like 1 in Cardiovascular Disease and Inflammation.Mini Rev Med Chem. 2019;19(16):1379-1389. doi: 10.2174/1389557519666190312161551.
507 Binding of FUN14 Domain Containing 1 With Inositol 1,4,5-Trisphosphate Receptor in Mitochondria-Associated Endoplasmic Reticulum Membranes Maintains Mitochondrial Dynamics and Function in Hearts in Vivo.Circulation. 2017 Dec 5;136(23):2248-2266. doi: 10.1161/CIRCULATIONAHA.117.030235. Epub 2017 Sep 23.
508 Effect of Adaptive Servo-Ventilation on Periodic Limb Movements in Sleep in Patients With Heart Failure.Am J Cardiol. 2019 Feb 15;123(4):632-637. doi: 10.1016/j.amjcard.2018.11.014. Epub 2018 Nov 24.
509 Cardiac Gab1 deletion leads to dilated cardiomyopathy associated with mitochondrial damage and cardiomyocyte apoptosis.Cell Death Differ. 2016 Apr;23(4):695-706. doi: 10.1038/cdd.2015.143. Epub 2015 Oct 30.
510 MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts.J Am Heart Assoc. 2017 Feb 10;6(2):e003601. doi: 10.1161/JAHA.116.003601.
511 Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis. Circulation. 2006 Jul 4;114(1 Suppl):I16-20. doi: 10.1161/CIRCULATIONAHA.105.000448.
512 Growth differentiation factor 11 is involved in isoproterenolinduced heart failure.Mol Med Rep. 2019 May;19(5):4109-4118. doi: 10.3892/mmr.2019.10077. Epub 2019 Mar 22.
513 G-protein beta-3 subunit genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine: results of A-HeFT.JACC Heart Fail. 2014 Dec;2(6):551-7. doi: 10.1016/j.jchf.2014.04.016. Epub 2014 Oct 8.
514 Sex- and age-dependent human transcriptome variability: implications for chronic heart failure.Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2754-9. doi: 10.1073/pnas.0436564100. Epub 2003 Feb 24.
515 T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF.Clin Res Cardiol. 2019 Feb;108(2):133-141. doi: 10.1007/s00392-018-1331-2. Epub 2018 Jul 26.
516 Outcomes following implantable cardioverter-defibrillator generator replacement in patients with recovered left ventricular systolic function: The National Cardiovascular Data Registry.Heart Rhythm. 2019 May;16(5):733-740. doi: 10.1016/j.hrthm.2018.11.005. Epub 2018 Nov 7.
517 GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A.Am J Physiol Heart Circ Physiol. 2009 Oct;297(4):H1446-52. doi: 10.1152/ajpheart.00513.2009. Epub 2009 Aug 7.
518 Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses.PLoS Genet. 2017 Jul 21;13(7):e1006921. doi: 10.1371/journal.pgen.1006921. eCollection 2017 Jul.
519 Uroguanylin: a new actor in the energy balance movie.J Mol Endocrinol. 2018 Feb;60(2):R31-R38. doi: 10.1530/JME-17-0263. Epub 2017 Dec 4.
520 Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure.J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):844-859. doi: 10.1002/jcsm.12322. Epub 2018 Aug 30.
521 HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure.Cardiovasc Res. 2020 Mar 1;116(3):605-618. doi: 10.1093/cvr/cvz182.
522 Relationship Between Handgrip Strength and Length of Stay for Left Ventricular Assist Device Implantation.Nutr Clin Pract. 2017 Feb;32(1):98-102. doi: 10.1177/0884533616665926. Epub 2016 Sep 25.
523 Circ-HIPK3 Strengthens the Effects of Adrenaline in Heart Failure by MiR-17-3p - ADCY6 Axis.Int J Biol Sci. 2019 Sep 7;15(11):2484-2496. doi: 10.7150/ijbs.36149. eCollection 2019.
524 The role of 3'-untranslated region (3'-UTR) mediated mRNA stability in cardiovascular pathophysiology.Mol Cell Biochem. 2001 Aug;224(1-2):53-67. doi: 10.1023/a:1011982932645.
525 Homeodomain only protein x is down-regulated in human heart failure.J Mol Cell Cardiol. 2011 Jun;50(6):1056-8. doi: 10.1016/j.yjmcc.2011.02.015. Epub 2011 Mar 5.
526 Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy.Int J Cardiol. 2018 Apr 15;257:283-290. doi: 10.1016/j.ijcard.2017.10.102. Epub 2017 Nov 10.
527 The increased expression of the inducible Hsp70 (HSP70A1A) in serum of patients with heart failure and its protective effect against the cardiotoxic agent doxorubicin.Mol Cell Biochem. 2019 May;455(1-2):41-59. doi: 10.1007/s11010-018-3469-7. Epub 2018 Nov 2.
528 Antioxidant amelioration of dilated cardiomyopathy caused by conditional deletion of NEMO/IKKgamma in cardiomyocytes.Circ Res. 2010 Jan 8;106(1):133-44. doi: 10.1161/CIRCRESAHA.109.202200. Epub 2009 Oct 22.
529 Common variants in IL-17A/IL-17RA axis contribute to predisposition to and progression of congestive heart failure.Medicine (Baltimore). 2016 Jul;95(27):e4105. doi: 10.1097/MD.0000000000004105.
530 Interleukin-18 mediates interleukin-1-induced cardiac dysfunction.Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H1025-31. doi: 10.1152/ajpheart.00795.2013. Epub 2014 Feb 14.
531 Interleukin-34 Levels Were Associated with Prognosis in Patients with Acute Myocardial Infarction.Int Heart J. 2019 Nov 30;60(6):1259-1267. doi: 10.1536/ihj.19-111. Epub 2019 Nov 15.
532 Utility and safety of tocilizumab in Takayasu arteritis with severe heart failure and muscle wasting.ESC Heart Fail. 2019 Aug;6(4):894-897. doi: 10.1002/ehf2.12487. Epub 2019 Jul 11.
533 Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspects.Br J Pharmacol. 2008 Mar;153 Suppl 1(Suppl 1):S414-27. doi: 10.1038/bjp.2008.1. Epub 2008 Feb 4.
534 High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles.PLoS One. 2012;7(8):e43340. doi: 10.1371/journal.pone.0043340. Epub 2012 Aug 17.
535 Rationale and design of the IMPACT EU-trial: improve management of heart failure with procalcitonin biomarkers in cardiology (BIC)-18.Biomarkers. 2018 Feb;23(1):97-103. doi: 10.1080/1354750X.2017.1420823. Epub 2018 Jan 8.
536 Relaxin Family Member Insulin-Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models.J Am Heart Assoc. 2018 Jun 10;7(12):e008441. doi: 10.1161/JAHA.117.008441.
537 Increasing trends in hospitalisations due to atrial fibrillation in Australia from 1993 to 2013.Heart. 2019 Sep;105(17):1358-1363. doi: 10.1136/heartjnl-2018-314471. Epub 2019 Apr 1.
538 Identification of potentially critical genes in the development of heart failure after ST-segment elevation myocardial infarction (STEMI).J Cell Biochem. 2019 May;120(5):7771-7777. doi: 10.1002/jcb.28051. Epub 2018 Nov 28.
539 Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy.Gene. 2013 Jan 10;512(2):206-10. doi: 10.1016/j.gene.2012.10.055. Epub 2012 Nov 1.
540 Catheter Ablation Versus Best Medical Therapy in Patients With Persistent Atrial Fibrillation and Congestive Heart Failure: The Randomized AMICA Trial.Circ Arrhythm Electrophysiol. 2019 Dec;12(12):e007731. doi: 10.1161/CIRCEP.119.007731. Epub 2019 Nov 25.
541 Induction by left ventricular overload and left ventricular failure of the human Jumonji gene (JARID2) encoding a protein that regulates transcription and reexpression of a protective fetal program.J Thorac Cardiovasc Surg. 2008 Sep;136(3):709-16. doi: 10.1016/j.jtcvs.2008.02.020. Epub 2008 Jun 9.
542 JDP2 overexpression provokes cardiac dysfunction in mice.Sci Rep. 2018 May 16;8(1):7647. doi: 10.1038/s41598-018-26052-w.
543 RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6172-6180. doi: 10.1073/pnas.1822176116. Epub 2019 Mar 13.
544 MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.Cell. 2016 Oct 20;167(3):722-738.e23. doi: 10.1016/j.cell.2016.09.052.
545 S38G single-nucleotide polymorphism at the KCNE1 locus is associated with heart failure.Heart Rhythm. 2010 Mar;7(3):363-7. doi: 10.1016/j.hrthm.2009.11.032. Epub 2009 Dec 2.
546 LCZ696 Therapy Reduces Ventricular Tachyarrhythmia Inducibility in a Myocardial Infarction-Induced Heart Failure Rat Model.Cardiovasc Ther. 2019 Jul 1;2019:6032631. doi: 10.1155/2019/6032631. eCollection 2019.
547 Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes.J Clin Invest. 2011 Jul;121(7):2641-50. doi: 10.1172/JCI44641. Epub 2011 Jun 6.
548 Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure.Circ Res. 2019 Jul 19;125(3):265-281. doi: 10.1161/CIRCRESAHA.119.314951. Epub 2019 Jul 18.
549 Cardiac K(2P)13.1 (THIK-1) two-pore-domain K(+) channels: Pharmacological regulation and remodeling in atrial fibrillation.Prog Biophys Mol Biol. 2019 Jul;144:128-138. doi: 10.1016/j.pbiomolbio.2018.06.009. Epub 2018 Jul 6.
550 Increased kielin/chordin-like protein levels are associated with the severity of heart failure.Clin Chim Acta. 2018 Nov;486:381-386. doi: 10.1016/j.cca.2018.08.033. Epub 2018 Aug 23.
551 MiR-147b inhibits cell viability and promotes apoptosis of rat H9c2 cardiomyocytes via down-regulating KLF13 expression.Acta Biochim Biophys Sin (Shanghai). 2018 Mar 1;50(3):288-297. doi: 10.1093/abbs/gmx144.
552 Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.J Clin Invest. 2015 Oct 1;125(10):3819-30. doi: 10.1172/JCI79048. Epub 2015 Sep 14.
553 KLF2 mediates enhanced chemoreflex sensitivity, disordered breathing and autonomic dysregulation in heart failure.J Physiol. 2018 Aug;596(15):3171-3185. doi: 10.1113/JP273805. Epub 2017 Oct 11.
554 Mechanistic Role of Thioredoxin 2 in Heart Failure.Adv Exp Med Biol. 2017;982:265-276. doi: 10.1007/978-3-319-55330-6_14.
555 Heat-shock transcription factor 1 is critically involved in the ischaemia-induced cardiac hypertrophy via JAK2/STAT3 pathway.J Cell Mol Med. 2018 Sep;22(9):4292-4303. doi: 10.1111/jcmm.13713. Epub 2018 Jul 11.
556 Assessment of Galectin-3 Polymorphism in Subjects with Chronic Chagas Disease.Arq Bras Cardiol. 2015 Nov;105(5):472-8. doi: 10.5935/abc.20150105. Epub 2015 Aug 25.
557 Left Atrial Dynamics During Exercise in Mitral Regurgitation of Primary and Secondary Origin: Pathophysiological Insights by Exercise Echocardiography Combined With Gas Exchange Analysis.JACC Cardiovasc Imaging. 2020 Jan;13(1 Pt 1):25-40. doi: 10.1016/j.jcmg.2018.12.031. Epub 2019 Mar 13.
558 Cardiac-specific knockout of Lmod2 results in a severe reduction in myofilament force production and rapid cardiac failure.J Mol Cell Cardiol. 2018 Sep;122:88-97. doi: 10.1016/j.yjmcc.2018.08.009. Epub 2018 Aug 11.
559 Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis.Circulation. 2018 Sep 18;138(12):1224-1235. doi: 10.1161/CIRCULATIONAHA.118.035420.
560 LTBP-2 acts as a novel marker in human heart failure - a preliminary study.Biomarkers. 2012 Aug;17(5):407-15. doi: 10.3109/1354750X.2012.677860. Epub 2012 Apr 19.
561 RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.Trends Cardiovasc Med. 2013 Jan;23(1):5-8. doi: 10.1016/j.tcm.2012.08.003. Epub 2012 Aug 31.
562 The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload.Sci Rep. 2019 Jun 24;9(1):9206. doi: 10.1038/s41598-019-45651-9.
563 Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community.J Am Heart Assoc. 2017 Aug 3;6(8):e006028. doi: 10.1161/JAHA.117.006028.
564 Early Postdischarge STOP-HF-Clinic Reduces 30-day Readmissions in Old and Frail Patients With Heart Failure.Rev Esp Cardiol (Engl Ed). 2017 Aug;70(8):631-638. doi: 10.1016/j.rec.2017.01.003. Epub 2017 Feb 16.
565 Hemodynamic Assessment of Patients With and Without Heart Failure Symptoms Supported by a Continuous-Flow Left Ventricular Assist Device.Mayo Clin Proc. 2018 Jul;93(7):895-903. doi: 10.1016/j.mayocp.2018.01.031. Epub 2018 Jun 19.
566 Can Functional Testing for Ischemia and Viability Guide Revascularization?.JACC Cardiovasc Imaging. 2017 Mar;10(3):354-364. doi: 10.1016/j.jcmg.2016.12.011.
567 MLP-deficient human pluripotent stem cell derived cardiomyocytes develop hypertrophic cardiomyopathy and heart failure phenotypes due to abnormal calcium handling.Cell Death Dis. 2019 Aug 13;10(8):610. doi: 10.1038/s41419-019-1826-4.
568 The challenge of cardiomyopathies and heart failure in pregnancy.Curr Opin Obstet Gynecol. 2018 Dec;30(6):378-384. doi: 10.1097/GCO.0000000000000496.
569 Porous Hydrogel-Encapsulated Photonic Barcodes for Multiplex Detection of Cardiovascular Biomarkers.ACS Sens. 2019 May 24;4(5):1384-1390. doi: 10.1021/acssensors.9b00352. Epub 2019 Apr 19.
570 Heart Failure and Cognitive Impairment in the Atherosclerosis Risk in Communities (ARIC) Study.J Gen Intern Med. 2018 Oct;33(10):1721-1728. doi: 10.1007/s11606-018-4556-x. Epub 2018 Jul 20.
571 Mitochondrial calcium uniporter inhibition provides cardioprotection in pressure overload-induced heart failure through autophagy enhancement.Int J Cardiol. 2018 Nov 15;271:161-168. doi: 10.1016/j.ijcard.2018.05.054. Epub 2018 May 20.
572 Effect of 6 wk of high-intensity one-legged cycling on functional sympatholysis and ATP signaling in patients with heart failure.Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H616-H626. doi: 10.1152/ajpheart.00379.2017. Epub 2017 Nov 22.
573 Downregulation of myocardial myocyte enhancer factor 2C and myocyte enhancer factor 2C-regulated gene expression in diabetic patients with nonischemic heart failure.Circulation. 2002 Jul 23;106(4):407-11. doi: 10.1161/01.cir.0000026392.80723.dc.
574 Meox1 accelerates myocardial hypertrophic decompensation through Gata4.Cardiovasc Res. 2018 Feb 1;114(2):300-311. doi: 10.1093/cvr/cvx222.
575 The N(6)-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy.Circulation. 2019 Jan 22;139(4):533-545. doi: 10.1161/CIRCULATIONAHA.118.036146.
576 Mitochondrial Dynamics in Tachycardiomyopathy.Cell Physiol Biochem. 2019;52(3):435-438. doi: 10.33594/000000031. Epub 2019 Mar 15.
577 Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.Front Physiol. 2019 Apr 10;10:382. doi: 10.3389/fphys.2019.00382. eCollection 2019.
578 Daily Supplementation with 4000 IU Vitamin D3 for Three Years Does Not Modify Cardiovascular Risk Markers in Patients with Advanced Heart Failure: The Effect of Vitamin D on Mortality in Heart Failure Trial.Ann Nutr Metab. 2019;74(1):62-68. doi: 10.1159/000495662. Epub 2018 Dec 14.
579 Depressed Myocardial Energetic Efficiency Increases Risk of Incident Heart Failure: The Strong Heart Study.J Clin Med. 2019 Jul 17;8(7):1044. doi: 10.3390/jcm8071044.
580 Potential roles of circulating matrix metalloproteinase-28 (MMP-28) in patients with atrial fibrillation.Life Sci. 2018 Jul 1;204:15-19. doi: 10.1016/j.lfs.2018.04.053. Epub 2018 May 2.
581 SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity.Circ Res. 2017 Jan 6;120(1):110-119. doi: 10.1161/CIRCRESAHA.116.309977. Epub 2016 Oct 11.
582 Third Annual Report From the ISHLT Mechanically Assisted Circulatory Support Registry: A comparison of centrifugal and axial continuous-flow left ventricular assist devices.J Heart Lung Transplant. 2019 Apr;38(4):352-363. doi: 10.1016/j.healun.2019.02.004.
583 The different roles for the advanced glycation end products axis in heart failure and acute coronary syndrome settings.Nutr Metab Cardiovasc Dis. 2019 Oct;29(10):1050-1060. doi: 10.1016/j.numecd.2019.06.014. Epub 2019 Jun 22.
584 Mon2 predicts poor outcome in ST-elevation myocardial infarction.J Intern Med. 2019 Mar;285(3):301-316. doi: 10.1111/joim.12847. Epub 2019 Jan 15.
585 Utility of nuclear stress imaging in predicting long-term outcomes one-year post CABG Surgery.J Nucl Cardiol. 2020 Dec;27(6):1970-1978. doi: 10.1007/s12350-018-01469-y. Epub 2018 Nov 5.
586 A common variant of RIP3 promoter region is associated with poor prognosis in heart failure patients by influencing SOX17 binding.J Cell Mol Med. 2019 Aug;23(8):5317-5328. doi: 10.1111/jcmm.14408. Epub 2019 May 31.
587 Novel role of mitochondrial GTPases 1 in pathological cardiac hypertrophy.J Mol Cell Cardiol. 2019 Mar;128:105-116. doi: 10.1016/j.yjmcc.2019.01.025. Epub 2019 Jan 29.
588 Skeletal Muscle Resident Progenitor Cells Coexpress Mesenchymal and Myogenic Markers and Are Not Affected by Chronic Heart Failure-Induced Dysregulations.Stem Cells Int. 2019 Jan 3;2019:5690345. doi: 10.1155/2019/5690345. eCollection 2019.
589 Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expression.PLoS One. 2009;4(4):e5144. doi: 10.1371/journal.pone.0005144. Epub 2009 Apr 9.
590 Generation of MLC-2v-tdTomato knock-in reporter mouse line.Genesis. 2018 Oct;56(10):e23256. doi: 10.1002/dvg.23256. Epub 2018 Nov 2.
591 Long-term outcome of 4 Korean families with hypertrophic cardiomyopathy caused by 4 different mutations.Clin Cardiol. 2010 Jul;33(7):430-8. doi: 10.1002/clc.20795.
592 Human atrial myosin light chain 1 expression attenuates heart failure.Adv Exp Med Biol. 2005;565:283-92; discussion 92, 405-15. doi: 10.1007/0-387-24990-7_21.
593 Identification of MYLK3 mutations in familial dilated cardiomyopathy.Sci Rep. 2017 Dec 13;7(1):17495. doi: 10.1038/s41598-017-17769-1.
594 YiQiFuMai powder injection ameliorates chronic heart failure through cross-talk between adipose tissue and cardiomyocytes via up-regulation of circulating adipokine omentin.Biomed Pharmacother. 2019 Nov;119:109418. doi: 10.1016/j.biopha.2019.109418. Epub 2019 Sep 7.
595 Myocardin mRNA is augmented in the failing myocardium: expression profiling in the porcine model and human dilated cardiomyopathy.J Mol Med (Berl). 2003 Sep;81(9):566-77. doi: 10.1007/s00109-003-0470-7. Epub 2003 Aug 13.
596 Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110. doi: 10.1073/pnas.1719309115. Epub 2018 Apr 9.
597 NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly.Cell Res. 2019 Sep;29(9):754-766. doi: 10.1038/s41422-019-0208-x. Epub 2019 Jul 31.
598 Calcium-dependent Nedd4-2 upregulation mediates degradation of the cardiac sodium channel Nav1.5: implications for heart failure.Acta Physiol (Oxf). 2017 Sep;221(1):44-58. doi: 10.1111/apha.12872. Epub 2017 Apr 6.
599 Differences in MEF2 and NFAT transcriptional pathways according to human heart failure aetiology.PLoS One. 2012;7(2):e30915. doi: 10.1371/journal.pone.0030915. Epub 2012 Feb 17.
600 Increased regulatory activity of the calcineurin/NFAT pathway in human heart failure.Eur J Heart Fail. 2004 Jan;6(1):3-9. doi: 10.1016/j.ejheart.2003.07.007.
601 A minireview of E4BP4/NFIL3 in heart failure.J Cell Physiol. 2018 Nov;233(11):8458-8466. doi: 10.1002/jcp.26790. Epub 2018 Jun 1.
602 Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart.PLoS One. 2016 Oct 20;11(10):e0164897. doi: 10.1371/journal.pone.0164897. eCollection 2016.
603 Assessment of nociceptin/orphanin FQ and micro-opioid receptor mRNA in the human right atrium.Br J Anaesth. 2010 Jun;104(6):698-704. doi: 10.1093/bja/aeq089. Epub 2010 Apr 21.
604 High- Versus Low-Gradient Severe Aortic Stenosis: Demographics, Clinical Outcomes, and Effects of the Initial Aortic Valve Replacement Strategy on Long-Term Prognosis.Circ Cardiovasc Interv. 2017 May;10(5):e004796. doi: 10.1161/CIRCINTERVENTIONS.116.004796.
605 Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.Circulation. 2017 Feb 28;135(9):881-897. doi: 10.1161/CIRCULATIONAHA.116.022852. Epub 2016 Dec 7.
606 Decreased nNOS in the PVN leads to increased sympathoexcitation in chronic heart failure: role for CAPON and Ang II.Cardiovasc Res. 2011 Nov 1;92(2):348-57. doi: 10.1093/cvr/cvr217. Epub 2011 Aug 10.
607 Increase of NADPH oxidase 3 in heart failure of hereditary cardiomyopathy (1).Can J Physiol Pharmacol. 2019 Sep;97(9):902-908. doi: 10.1139/cjpp-2019-0055. Epub 2019 Mar 21.
608 Association Between Plasma Brain Natriuretic Peptide and Overall Survival in Patients With Advanced Cancer: Preliminary Findings.J Pain Symptom Manage. 2019 Sep;58(3):465-471. doi: 10.1016/j.jpainsymman.2019.05.006. Epub 2019 May 22.
609 Receptor-interacting protein 140 overexpression impairs cardiac mitochondrial function and accelerates the transition to heart failure in chronically infarcted rats.Transl Res. 2017 Feb;180:91-102.e1. doi: 10.1016/j.trsl.2016.08.005. Epub 2016 Aug 31.
610 Wolf-Hirschhorn Syndrome Candidate 1 (whsc1) Functions as a Tumor Suppressor by Governing Cell Differentiation.Neoplasia. 2017 Aug;19(8):606-616. doi: 10.1016/j.neo.2017.05.001. Epub 2017 Jun 24.
611 MicroRNA-539 is up-regulated in failing heart, and suppresses O-GlcNAcase expression.J Biol Chem. 2014 Oct 24;289(43):29665-76. doi: 10.1074/jbc.M114.578682. Epub 2014 Sep 2.
612 Osteoglycin prevents cardiac dilatation and dysfunction after myocardial infarction through infarct collagen strengthening.Circ Res. 2015 Jan 30;116(3):425-36. doi: 10.1161/CIRCRESAHA.116.304599. Epub 2014 Dec 17.
613 Ablation of the stress protease OMA1 protects against heart failure in mice.Sci Transl Med. 2018 Mar 28;10(434):eaan4935. doi: 10.1126/scitranslmed.aan4935.
614 Cardiac inflammatory CD11b/c cells exert a protective role in hypertrophied cardiomyocyte by promoting TNFR(2)- and Orai3- dependent signaling.Sci Rep. 2019 Apr 15;9(1):6047. doi: 10.1038/s41598-019-42452-y.
615 Structural and myocardial dysfunction in heart failure beyond ejection fraction.Heart Fail Rev. 2020 Jan;25(1):9-17. doi: 10.1007/s10741-019-09828-8.
616 Pregnancy-associated plasma protein-A (PAPP-A) and the proform of the eosinophil major basic protein (ProMBP) are associated with increased risk of death in heart failure patients.Scand J Clin Lab Invest. 2017 Sep;77(5):352-357. doi: 10.1080/00365513.2017.1325926. Epub 2017 May 24.
617 PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism.Int J Mol Sci. 2018 May 16;19(5):1485. doi: 10.3390/ijms19051485.
618 Effects of two Gbetagamma-binding proteins--N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus (betaARKct)--in heart failure.Gene Ther. 2003 Aug;10(16):1354-61. doi: 10.1038/sj.gt.3301995.
619 The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells.PLoS One. 2011;6(5):e19724. doi: 10.1371/journal.pone.0019724. Epub 2011 May 23.
620 Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.PLoS One. 2009;4(5):e5232. doi: 10.1371/journal.pone.0005232. Epub 2009 May 1.
621 Adrenergic Regulation of Drp1-Driven Mitochondrial Fission in Cardiac Physio-Pathology.Antioxidants (Basel). 2018 Dec 18;7(12):195. doi: 10.3390/antiox7120195.
622 Proenkephalin and prognosis in heart failure with preserved ejection fraction: a GREAT network study.Clin Res Cardiol. 2019 Aug;108(8):940-949. doi: 10.1007/s00392-019-01424-y. Epub 2019 Feb 14.
623 Profilin? contributes to cardiac injury induced by advanced glycation endproducts in rats.Mol Med Rep. 2017 Nov;16(5):6634-6641. doi: 10.3892/mmr.2017.7446. Epub 2017 Sep 8.
624 Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies.BMC Mol Biol. 2010 Mar 23;11:22. doi: 10.1186/1471-2199-11-22.
625 Novel Role for Pleckstrin Homology-Like Domain Family A, Member 3 in the Regulation of Pathological Cardiac Hypertrophy.J Am Heart Assoc. 2019 Aug 20;8(16):e011830. doi: 10.1161/JAHA.118.011830. Epub 2019 Aug 20.
626 Multiple faces of protein interacting with C kinase 1 (PICK1): Structure, function, and diseases.Neurochem Int. 2016 Sep;98:115-21. doi: 10.1016/j.neuint.2016.03.001. Epub 2016 Mar 9.
627 Stretch-activated channel Piezo1 is up-regulated in failure heart and cardiomyocyte stimulated by AngII.Am J Transl Res. 2017 Jun 15;9(6):2945-2955. eCollection 2017.
628 AMPK2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation.Circ Res. 2018 Mar 2;122(5):712-729. doi: 10.1161/CIRCRESAHA.117.312317. Epub 2017 Dec 28.
629 Assessing inflammation in Chinese subjects with subtypes of heart failure: an observational study of the Chinese PLA Hospital Heart Failure Registry.J Geriatr Cardiol. 2019 Apr;16(4):313-319. doi: 10.11909/j.issn.1671-5411.2019.04.002.
630 Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy.J Mol Cell Cardiol. 2013 May;58:199-208. doi: 10.1016/j.yjmcc.2013.01.015. Epub 2013 Jan 30.
631 Recessive variants in plakophilin-2 contributes to early-onset arrhythmogenic cardiomyopathy with severe heart failure.Europace. 2019 Jun 1;21(6):970-977. doi: 10.1093/europace/euz026.
632 Plin5 deficiency exacerbates pressure overload-induced cardiac hypertrophy and heart failure by enhancing myocardial fatty acid oxidation and oxidative stress.Free Radic Biol Med. 2019 Sep;141:372-382. doi: 10.1016/j.freeradbiomed.2019.07.006. Epub 2019 Jul 7.
633 Cardiac-specific inactivation of LPP3 in mice leads to myocardial dysfunction and heart failure.Redox Biol. 2018 Apr;14:261-271. doi: 10.1016/j.redox.2017.09.015. Epub 2017 Sep 28.
634 The lncRNA Plscr4 Controls Cardiac Hypertrophy by Regulating miR-214.Mol Ther Nucleic Acids. 2018 Mar 2;10:387-397. doi: 10.1016/j.omtn.2017.12.018. Epub 2017 Dec 30.
635 Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.PLoS Genet. 2018 Jan 10;14(1):e1007171. doi: 10.1371/journal.pgen.1007171. eCollection 2018 Jan.
636 Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.Nat Commun. 2017 Sep 18;8(1):578. doi: 10.1038/s41467-017-00654-w.
637 Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1 (Peroxisome Proliferator-Activated Receptor- Coactivator-1) Dysregulation.Circ Heart Fail. 2019 Mar;12(3):e005529. doi: 10.1161/CIRCHEARTFAILURE.118.005529.
638 -Thromboglobulin and incident cardiovascular disease risk: The Atherosclerosis Risk in Communities study.Thromb Res. 2017 Jul;155:116-120. doi: 10.1016/j.thromres.2017.05.016. Epub 2017 May 17.
639 Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure.Curr Drug Metab. 2008 Feb;9(2):122-8. doi: 10.2174/138920008783571792.
640 Catabolism of branched-chain amino acids in heart failure: insights from genetic models.Pediatr Cardiol. 2011 Mar;32(3):305-10. doi: 10.1007/s00246-010-9856-9. Epub 2011 Jan 7.
641 Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.Circulation. 2018 Oct 9;138(15):1569-1581. doi: 10.1161/CIRCULATIONAHA.118.034361.
642 AAV-9 mediated phosphatase-1 inhibitor-1 overexpression improves cardiac contractility in unchallenged mice but is deleterious in pressure-overload.Gene Ther. 2018 Jan;25(1):13-19. doi: 10.1038/gt.2017.97. Epub 2018 Jan 19.
643 Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure.Nat Commun. 2019 Jun 24;10(1):2760. doi: 10.1038/s41467-019-10591-5.
644 PR65A phosphorylation regulates PP2A complex signaling.PLoS One. 2014 Jan 21;9(1):e85000. doi: 10.1371/journal.pone.0085000. eCollection 2014.
645 Oxidative stress and mitochondrial DNA damage in heart failure.Circ J. 2008;72 Suppl A:A31-7. doi: 10.1253/circj.cj-08-0014. Epub 2008 Sep 4.
646 BDNF contributes to the skeletal muscle anti-atrophic effect of exercise training through AMPK-PGC1 signaling in heart failure mice.Arch Med Sci. 2019 Jan;15(1):214-222. doi: 10.5114/aoms.2018.81037. Epub 2018 Dec 30.
647 Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure.PLoS One. 2013 May 31;8(5):e64603. doi: 10.1371/journal.pone.0064603. Print 2013.
648 Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.J Biol Chem. 2003 Nov 7;278(45):44935-48. doi: 10.1074/jbc.M307696200. Epub 2003 Aug 21.
649 Protein kinase C regulates internal initiation of translation of the GATA-4 mRNA following vasopressin-induced hypertrophy of cardiac myocytes.J Biol Chem. 2007 Mar 30;282(13):9505-9516. doi: 10.1074/jbc.M608874200. Epub 2007 Feb 6.
650 Increased myocardial Rab GTPase expression: a consequence and cause of cardiomyopathy.Circ Res. 2001 Dec 7;89(12):1130-7. doi: 10.1161/hh2401.100427.
651 Significance of the CAPRI risk score to predict heart failure hospitalization post-TAVI: The CAPRI-HF study.Int J Cardiol. 2019 Dec 1;296:98-102. doi: 10.1016/j.ijcard.2019.08.033. Epub 2019 Aug 19.
652 A Splicing-Independent Function of RBM10 Controls Specific 3' UTR Processing to Regulate Cardiac Hypertrophy.Cell Rep. 2018 Sep 25;24(13):3539-3553. doi: 10.1016/j.celrep.2018.08.077.
653 Splicing Factor RBM20 Regulates Transcriptional Network of Titin Associated and Calcium Handling Genes in The Heart.Int J Biol Sci. 2018 Mar 9;14(4):369-380. doi: 10.7150/ijbs.24117. eCollection 2018.
654 RNA binding protein 24 deletion disrupts global alternative splicing and causes dilated cardiomyopathy.Protein Cell. 2019 Jun;10(6):405-416. doi: 10.1007/s13238-018-0578-8. Epub 2018 Sep 28.
655 Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure.Circulation. 2011 Sep 6;124(10):1124-31. doi: 10.1161/CIRCULATIONAHA.111.044495. Epub 2011 Aug 22.
656 REEP5 (Receptor Accessory Protein 5) Acts as a Sarcoplasmic Reticulum Membrane Sculptor to Modulate Cardiac Function.J Am Heart Assoc. 2018 Feb 3;7(3):e007205. doi: 10.1161/JAHA.117.007205.
657 Is there a relationship between resistin levels and left ventricular end-diastolic pressure?.Anatol J Cardiol. 2018 Apr;19(4):267-272. doi: 10.14744/AnatolJCardiol.2018.66181.
658 RNA-sequencing analysis reveals new alterations in cardiomyocyte cytoskeletal genes in patients with heart failure.Lab Invest. 2014 Jun;94(6):645-53. doi: 10.1038/labinvest.2014.54. Epub 2014 Apr 7.
659 The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.Nat Med. 2017 Oct;23(10):1215-1219. doi: 10.1038/nm.4393. Epub 2017 Aug 28.
660 Ultrastructure and regulation of lateralized connexin43 in the failing heart.Circ Res. 2010 Apr 2;106(6):1153-63. doi: 10.1161/CIRCRESAHA.108.182147. Epub 2010 Feb 18.
661 Rnd3/RhoE Modulates Hypoxia-Inducible Factor 1/Vascular Endothelial Growth Factor Signaling by Stabilizing Hypoxia-Inducible Factor 1 and Regulates Responsive Cardiac Angiogenesis.Hypertension. 2016 Mar;67(3):597-605. doi: 10.1161/HYPERTENSIONAHA.115.06412. Epub 2016 Jan 18.
662 Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart.Circ Res. 1994 Feb;74(2):206-13. doi: 10.1161/01.res.74.2.206.
663 Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart.J Cardiovasc Transl Res. 2016 Dec;9(5-6):432-444. doi: 10.1007/s12265-016-9716-y. Epub 2016 Oct 31.
664 RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment.Pharmacogenomics J. 2013 Aug;13(4):330-4. doi: 10.1038/tpj.2012.22. Epub 2012 Jun 5.
665 Relationship of stroke volume to different patterns of Cheyne-Stokes respiration in heart failure.Sleep. 2019 Apr 1;42(4):zsy262. doi: 10.1093/sleep/zsy262.
666 Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy.J Exp Med. 2007 May 14;204(5):1227-35. doi: 10.1084/jem.20070145. Epub 2007 May 7.
667 Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties.PLoS One. 2012;7(5):e37401. doi: 10.1371/journal.pone.0037401. Epub 2012 May 24.
668 Short-Term Effects of Tolvaptan in PatientsWith Acute Heart Failure andVolume Overload.J Am Coll Cardiol. 2017 Mar 21;69(11):1409-1419. doi: 10.1016/j.jacc.2016.12.035.
669 Syndecan-4 deficiency accelerates the transition from compensated hypertrophy to heart failure following pressure overload.Cardiovasc Pathol. 2017 May-Jun;28:74-79. doi: 10.1016/j.carpath.2017.03.008. Epub 2017 Mar 30.
670 In-hospital outcomes of delayed stenting in hemodynamically stable patients with ST-segment elevation myocardial infarction: the CCC (Care for Cardiovascular Disease in China) project.Cardiovasc Diagn Ther. 2019 Oct;9(5):462-471. doi: 10.21037/cdt.2019.08.10.
671 Immature surfactant protein-B impairs the antioxidant capacity of HDL.Int J Cardiol. 2019 Jun 15;285:53-58. doi: 10.1016/j.ijcard.2019.02.057. Epub 2019 Feb 27.
672 SLMAP-3 is downregulated in human dilated ventricles and its overexpression promotes cardiomyocyte response to adrenergic stimuli by increasing intracellular calcium.Can J Physiol Pharmacol. 2019 Jul;97(7):623-630. doi: 10.1139/cjpp-2018-0660. Epub 2019 Mar 11.
673 Decreased sarcolipin protein expression and enhanced sarco(endo)plasmic reticulum Ca2+ uptake in human atrial fibrillation.Biochem Biophys Res Commun. 2011 Jun 24;410(1):97-101. doi: 10.1016/j.bbrc.2011.05.113. Epub 2011 May 25.
674 Heart Transplantation from Biventricular Support in Infant with Novel SMYD1 Mutation.Pediatr Cardiol. 2019 Dec;40(8):1745-1747. doi: 10.1007/s00246-019-02139-7. Epub 2019 Jul 5.
675 Genetically Low Antioxidant Protection and Risk of Cardiovascular Disease and Heart Failure in Diabetic Subjects.EBioMedicine. 2015 Nov 14;2(12):2010-5. doi: 10.1016/j.ebiom.2015.11.026. eCollection 2015 Dec.
676 Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3436-E3445. doi: 10.1073/pnas.1717423115. Epub 2018 Mar 26.
677 Defining new mechanistic roles for II spectrin in cardiac function.J Biol Chem. 2019 Jun 14;294(24):9576-9591. doi: 10.1074/jbc.RA119.007714. Epub 2019 May 7.
678 Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction.Dis Model Mech. 2012 Jul;5(4):481-91. doi: 10.1242/dmm.009456. Epub 2012 Apr 5.
679 miR-1 mediated suppression of Sorcin regulates myocardial contractility through modulation of Ca2+ signaling.J Mol Cell Cardiol. 2012 May;52(5):1027-37. doi: 10.1016/j.yjmcc.2012.01.020. Epub 2012 Feb 4.
680 Food groups and risk of coronary heart disease, stroke and heart failure: A systematic review and dose-response meta-analysis of prospective studies.Crit Rev Food Sci Nutr. 2019;59(7):1071-1090. doi: 10.1080/10408398.2017.1392288. Epub 2017 Nov 7.
681 Enhanced store-operated Ca(2+) influx and ORAI1 expression in ventricular fibroblasts from human failing heart.Biol Open. 2017 Mar 15;6(3):326-332. doi: 10.1242/bio.022632.
682 The SLMAP/Striatin complex: An emerging regulator of normal and abnormal cardiac excitation-contraction coupling.Eur J Pharmacol. 2019 Sep 5;858:172491. doi: 10.1016/j.ejphar.2019.172491. Epub 2019 Jun 21.
683 Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure.JAMA Cardiol. 2019 Jan 1;4(1):25-33. doi: 10.1001/jamacardio.2018.3965.
684 Mineralocorticoid receptor antagonists in patients with heart failure: current experience and future perspectives.Eur Heart J Cardiovasc Pharmacother. 2017 Jan;3(1):48-57. doi: 10.1093/ehjcvp/pvw016. Epub 2016 Aug 2.
685 miR-146a Suppresses SUMO1 Expression and Induces Cardiac Dysfunction in Maladaptive Hypertrophy.Circ Res. 2018 Aug 31;123(6):673-685. doi: 10.1161/CIRCRESAHA.118.312751.
686 Involvement of activated SUMO-2 conjugation in cardiomyopathy.Biochim Biophys Acta. 2015 Jul;1852(7):1388-99. doi: 10.1016/j.bbadis.2015.03.013. Epub 2015 Apr 6.
687 Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure.PLoS One. 2018 Aug 20;13(8):e0201160. doi: 10.1371/journal.pone.0201160. eCollection 2018.
688 Mitsugumin 29 regulates t-tubule architecture in the failing heart.Sci Rep. 2017 Jul 13;7(1):5328. doi: 10.1038/s41598-017-05284-2.
689 Electrophysiologic and anatomic factors predictive of a need for touch-up radiofrequency application for complete pulmonary vein isolation: Comparison between hot balloon- and cryoballoon-based ablation.J Cardiovasc Electrophysiol. 2019 Aug;30(8):1261-1269. doi: 10.1111/jce.13989. Epub 2019 Jun 11.
690 Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury.Circ Res. 2010 Jun 11;106(11):1692-702. doi: 10.1161/CIRCRESAHA.109.214346. Epub 2010 Apr 22.
691 TFAM overexpression reduces pathological cardiac remodeling.Mol Cell Biochem. 2019 Apr;454(1-2):139-152. doi: 10.1007/s11010-018-3459-9. Epub 2018 Oct 23.
692 Diferric transferrin regulates transferrin receptor 2 protein stability.Blood. 2004 Dec 15;104(13):4287-93. doi: 10.1182/blood-2004-06-2477. Epub 2004 Aug 19.
693 Translocase of Inner Membrane 50 Functions as a Novel Protective Regulator of Pathological Cardiac Hypertrophy.J Am Heart Assoc. 2017 Apr 21;6(4):e004346. doi: 10.1161/JAHA.116.004346.
694 Efficacy and safety of DPP-4 inhibitors in patients with type 2 diabetes: Meta-analysis of placebo-controlled randomized clinical trials.Diabetes Metab. 2017 Feb;43(1):48-58. doi: 10.1016/j.diabet.2016.09.005. Epub 2016 Oct 10.
695 Analyses of long non-coding RNA and mRNA profiles in right ventricle myocardium of acute right heart failure in pulmonary arterial hypertension rats.Biomed Pharmacother. 2018 Oct;106:1108-1115. doi: 10.1016/j.biopha.2018.07.057. Epub 2018 Jul 17.
696 Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1.Cardiovasc Res. 2008 Mar 1;77(4):757-65. doi: 10.1093/cvr/cvm083. Epub 2007 Dec 4.
697 Sensitivity analysis revealing the effect of modulating ionic mechanisms on calcium dynamics in simulated human heart failure.PLoS One. 2017 Nov 8;12(11):e0187739. doi: 10.1371/journal.pone.0187739. eCollection 2017.
698 Targeting Transmembrane BAX Inhibitor Motif Containing 1 Alleviates Pathological Cardiac Hypertrophy.Circulation. 2018 Apr 3;137(14):1486-1504. doi: 10.1161/CIRCULATIONAHA.117.031659. Epub 2017 Dec 11.
699 Dysregulated Zn(2+) homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca(2+) leakage.J Biol Chem. 2017 Aug 11;292(32):13361-13373. doi: 10.1074/jbc.M117.781708. Epub 2017 Jun 19.
700 TOR1AIP1 as a cause of cardiac failure and recessive limb-girdle muscular dystrophy.Neuromuscul Disord. 2016 Aug;26(8):500-3. doi: 10.1016/j.nmd.2016.05.013. Epub 2016 May 24.
701 Ebstein anomaly, left ventricular non-compaction, and early onset heart failure associated with a de novo -tropomyosin gene mutation.Am J Med Genet A. 2016 Aug;170(8):2186-90. doi: 10.1002/ajmg.a.37745. Epub 2016 May 13.
702 Cardioprotective Role of Tumor Necrosis Factor Receptor-Associated Factor 2 by Suppressing Apoptosis and Necroptosis.Circulation. 2017 Aug 22;136(8):729-742. doi: 10.1161/CIRCULATIONAHA.116.026240. Epub 2017 Jun 1.
703 Tripartite motif 32 prevents pathological cardiac hypertrophy.Clin Sci (Lond). 2016 May 1;130(10):813-28. doi: 10.1042/CS20150619. Epub 2016 Feb 16.
704 Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding.PLoS One. 2014 Mar 3;9(3):e89621. doi: 10.1371/journal.pone.0089621. eCollection 2014.
705 [Salubrinal improves cardiac function in rats with heart failure post myocardial infarction through reducing endoplasmic reticulum stress-associated apoptosis].Zhonghua Xin Xue Guan Bing Za Zhi. 2016 Jun 24;44(6):494-500. doi: 10.3760/cma.j.issn.0253-3758.2016.06.008.
706 Response of caspase-independent apoptotic factors to high salt diet-induced heart failure.J Mol Cell Cardiol. 2007 Mar;42(3):678-86. doi: 10.1016/j.yjmcc.2007.01.001. Epub 2007 Jan 9.
707 Down-regulation of FKBP12.6 and SERCA2a contributes to acute heart failure in septic shock and is related to an up-regulated endothelin signalling pathway.J Pharm Pharmacol. 2007 Jul;59(7):977-84. doi: 10.1211/jpp.59.7.0010.
708 Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.Circ Res. 2002 Nov 29;91(11):1056-62. doi: 10.1161/01.res.0000045088.59360.b7.
709 Adriamycin induced myocardial failure in rats: protective role of Centella asiatica.Mol Cell Biochem. 2007 Jan;294(1-2):55-63. doi: 10.1007/s11010-006-9245-0. Epub 2006 Jun 20.
710 Growth hormone attenuates skeletal muscle changes in experimental chronic heart failure.Growth Horm IGF Res. 2010 Apr;20(2):149-55. doi: 10.1016/j.ghir.2009.11.007. Epub 2010 Jan 8.
711 Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure.Physiol Genomics. 2012 Feb 1;44(2):162-72. doi: 10.1152/physiolgenomics.00016.2011. Epub 2011 Nov 29.
712 Depressed responsiveness of phospholipase C isoenzymes to phosphatidic acid in congestive heart failure.J Mol Cell Cardiol. 2001 Mar;33(3):431-40. doi: 10.1006/jmcc.2000.1315.
713 Ventricular adrenomedullin system in the transition from LVH to heart failure in rats.Hypertension. 2003 Mar;41(3):512-8. doi: 10.1161/01.HYP.0000053447.64213.C4. Epub 2003 Feb 3.
714 Renalase deficiency in heart failure model of rats--a potential mechanism underlying circulating norepinephrine accumulation.PLoS One. 2011 Jan 31;6(1):e14633. doi: 10.1371/journal.pone.0014633.
715 Phosphoproteome mapping of cardiomyocyte mitochondria in a rat model of heart failure.Mol Cell Biochem. 2014 Apr;389(1-2):159-67. doi: 10.1007/s11010-013-1937-7. Epub 2014 Jan 7.