General Information of Disease (ID: DISS7D1V)

Disease Name leukaemia
Synonyms
leukemia; leukaemia; pediatric leukemia (disease); paediatric leukaemia (disease); leukemia (disease) of childhood; leukaemia (disease) of childhood; childhood leukemia (disease); childhood leukemia; childhood leukaemia (disease)
Disease Class 2A60-2B33: Leukaemia
Definition An acute or chronic leukemia that occurs during childhood.
Disease Hierarchy
DISNAKFL: Leukemia
DISS6SNG: Malignant neoplasm
DISS7D1V: leukaemia
ICD Code
ICD-11
ICD-11: 2A60-2B33
ICD-10
ICD-10: C91-C95
ICD-9
ICD-9: 204-208
Expand ICD-9
2.04E+14
Disease Identifiers
MONDO ID
MONDO_0004355
UMLS CUI
C1332977
MedGen ID
234132

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 9 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Acalabrutinib DM7GCVW Approved NA [1]
Bendamustine hydrochloride DMFH15Z Approved Small molecular drug [2]
Denileukin diftitox DMMHR1U Approved NA [3]
HUMAN CORTICOTROPIN-RELEASING HORMONE DM4RKRI Approved NA [4]
Lurbinectedin DMEFRTZ Approved Small molecular drug [5]
Methotrexate DM2TEOL Approved Small molecular drug [6]
Nelarabine DMB6VEG Approved Small molecular drug [7]
Quadracel DMH832D Approved NA [8]
Quizartinib DM8Y4JS Approved Small molecular drug [9]
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⏷ Show the Full List of 9 Drug(s)
This Disease is Treated as An Indication in 101 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ABL 001 DMMF5K4 Phase 3 NA [10]
HSV-Tk DMD5P1C Phase 3 NA [11]
Lmprime P66 DMFMNZB Phase 3 NA [12]
MACI DMS3SPV Phase 3 NA [13]
NVP-LAQ824 DM8JWNA Phase 3 Small molecular drug [14]
Radotinib DMWA74Y Phase 3 Small molecular drug [15]
KamRAB DM8ZWSF Phase 2/3 NA [16]
AG-858 DMNQ5T2 Phase 2 Vaccine [17]
AVR118 DMLWRON Phase 2 NA [18]
CAR-T cells targeting CD22 DM6XN4C Phase 2 CAR T Cell Therapy [19]
CAR-T cells targeting CD30 DML0KWM Phase 2 CAR T Cell Therapy [19]
CART-19 DMHQKN6 Phase 2 CAR T Cell Therapy [20]
CB-839 DM094UH Phase 2 NA [21]
CD19-targeting CAR T cells DMQJBUK Phase 2 CAR T Cell Therapy [22]
Daporinad DMCU74R Phase 2 Small molecular drug [23]
GSK2110183 DMZHB37 Phase 2 Small molecular drug [24]
IRX-2 DMODLN7 Phase 2 NA [25]
Itarnafloxin DMCY9PO Phase 2 Small molecular drug [26]
JVRS-100 DMPMU38 Phase 2 Vaccine [27]
LG-740 DM01OPD Phase 2 NA [28]
Lumiliximab DMLTI39 Phase 2 Antibody [29]
MDX-1342 DMKMSC4 Phase 2 Antibody [30]
ONC201 DMM5SCF Phase 2 NA [11]
Plague vaccine DMT3PJP Phase 2 NA [31]
TOL-3021 DMW17KS Phase 2 NA [32]
WT1 peptide vaccine DMZ67Q0 Phase 2 Vaccine [33]
[131I]-BC8 DMV86DY Phase 2 Antibody [34]
4SCAR19/22 T cells DMI8TW3 Phase 1/2 CAR T Cell Therapy [35]
AFX-9154 DM59ILU Phase 1/2 NA [36]
Anti-BCMA-CAR-transduced T cells DMZ18IO Phase 1/2 CAR T Cell Therapy [37]
Anti-CD123-CAR-transduced T cells DMFV6TY Phase 1/2 CAR T Cell Therapy [38]
Anti-CD19 CAR-T cells DM1EH9D Phase 1/2 CAR T Cell Therapy [39]
Anti-CD19-CAR-T cells DMNTP23 Phase 1/2 CAR T Cell Therapy [40]
Anti-CD20-CAR-transduced T cells DMXMK30 Phase 1/2 CAR T Cell Therapy [41]
Anti-CD22 CAR-T cells DMY6U8R Phase 1/2 CAR T Cell Therapy [39]
Anti-CD22-CAR-transduced T cells DMTO9VF Phase 1/2 CAR T Cell Therapy [42]
Anti-CD30-CAR-transduced T cells DMTZSPJ Phase 1/2 CAR T Cell Therapy [43]
AT9183 DM93VAC Phase 1/2 NA [44]
Autologous CD19-targeting CAR T cells DMLOGI4 Phase 1/2 CAR T Cell Therapy [45]
Beclanorsen DMXVRI0 Phase 1/2 Antisense drug [46]
BI 1206 DMTOMWB Phase 1/2 Antibody [47]
CAR-T cells targeting BCMA DMENIQ7 Phase 1/2 CAR T Cell Therapy [19]
CAR-T cells targeting CD19 DMIM9TZ Phase 1/2 CAR T Cell Therapy [19]
CAR-T cells targeting CLL1 DMCPM92 Phase 1/2 CAR T Cell Therapy [19]
CART-19/22 DMX0R1E Phase 1/2 CAR T Cell Therapy [48]
CD19 and CD20 CAR-T Cells DMRJ3ND Phase 1/2 CAR T Cell Therapy [49]
CD19 and CD22 CAR-T Cells DM581CS Phase 1/2 CAR T Cell Therapy [49]
CD19-directed CAR-T cells DMKQRUJ Phase 1/2 CAR T Cell Therapy [50]
CD22-Targeted CAR-T cells DM61MBG Phase 1/2 CAR T Cell Therapy [51]
Chimeric Antigen Receptor Modified T cells Targeting CD19 DMHNFXR Phase 1/2 CAR T Cell Therapy [52]
IM19 CAR-T DMKV5D6 Phase 1/2 CAR T Cell Therapy [53]
JCAR017 DMJV2IF Phase 1/2 CAR T Cell Therapy [54]
MyVax DMFIWUL Phase 1/2 NA [55]
SAR440234 DM6M8O4 Phase 1/2 Antibody [56]
SCRI-huCAR19v1 DMS1NMO Phase 1/2 CAR T Cell Therapy [57]
UCART019 DMRJK26 Phase 1/2 CAR T Cell Therapy [58]
WT-4869 DM3FIMD Phase 1/2 NA [59]
AC430 DMPS6U9 Phase 1 Small molecular drug [60]
AFM11 DMIFJZD Phase 1 Antibody [61]
Allogeneic CART-19 DMCYV26 Phase 1 CAR T Cell Therapy [62]
Anti-BCMA CAR-T cells DMK25QD Phase 1 CAR T Cell Therapy [63]
Anti-CD123 CAR-T cells DMYIZFW Phase 1 CAR T Cell Therapy [63]
Anti-CD19 DM0L6HL Phase 1 NA [11]
Anti-CD19 anti-CD20 Bispecific CAR-T DMCABUR Phase 1 CAR T Cell Therapy [64]
Anti-CD19 CAR-T cells DMUQ3C1 Phase 1 CAR T Cell Therapy [63]
Anti-CD19-CAR DMWKYSM Phase 1 CAR T Cell Therapy [65]
Anti-CD19-CAR T DMMRANJ Phase 1 CAR T Cell Therapy [66]
Anti-CD30 CAR-T cells DMTK78L Phase 1 CAR T Cell Therapy [63]
Anti-CD7 CAR-T cells DMMFL2P Phase 1 CAR T Cell Therapy [63]
ARI-0001 cells DMPLHBI Phase 1 CAR T Cell Therapy [67]
CC-90002 DMK0QDO Phase 1 Antibody [68]
CD10-CART DM0XDYT Phase 1 CAR T Cell Therapy [69]
CD19+ CAR T Cells DMGUQ8V Phase 1 CAR T Cell Therapy [70]
CD19-directed CAR-T cells DMETGAQ Phase 1 CAR T Cell Therapy [71]
CD19-targeted CART cells DMCZ3A2 Phase 1 CAR T Cell Therapy [72]
CD19/CD22 CAR T-Cells DMKA2FL Phase 1 CAR T Cell Therapy [73]
CD20-CART DMSJBUZ Phase 1 CAR T Cell Therapy [69]
CD22-CART DMHMPK1 Phase 1 CAR T Cell Therapy [69]
CD22-specific CAR T-cells also expressing an EGFRt DMP5V83 Phase 1 CAR T Cell Therapy [74]
CDX-1127 DMPVUGE Phase 1 NA [75]
Combotox DMA7PWX Phase 1 NA [76]
CSL-362-AML DM7I39W Phase 1 Antibody [77]
Donor-derived CD19/22 bispecific CAR-T cells DMZS350 Phase 1 CAR T Cell Therapy [71]
HuCART19 DMNAR29 Phase 1 CAR T Cell Therapy [78]
HuM195/rGel DMDZBTY Phase 1 Antibody [79]
ICAR19 CAR-T cells DMHG4Q9 Phase 1 CAR T Cell Therapy [80]
IMMU-114 DMTFUM4 Phase 1 Antibody [81]
INB-100 DM8PU34 Phase 1 Cell therapy [82]
Lintuzumab Ac-226 DMMOTIT Phase 1 Monoclonal antibody [83]
mab-216 DMBVC1R Phase 1 Monoclonal antibody [84]
Oncoquest-CLL DM1XWIJ Phase 1 NA [85]
Patient-derived CD19- and CD22 specific CAR DMZSD3T Phase 1 CAR T Cell Therapy [86]
Ragweed allergy vaccine DM5MMH7 Phase 1 NA [87]
RGA-1512 DMWQHWF Phase 1 NA [88]
ROR1R-CAR-T Cell DMIAK9P Phase 1 CAR T Cell Therapy [89]
Sleeping Beauty CAR-TCR DMVUL1H Phase 1 CAR T Cell Therapy [90]
XL-228 DMW8N72 Phase 1 Small molecular drug [91]
Anti-CD19 Chimeric Antigen Receptor T Cells DM6NVPT Clinical trial CAR T Cell Therapy [92]
CAR-CD19 T cell DMXU2D1 Clinical trial CAR T Cell Therapy [93]
CD19-targeted CAR-T cells DMLPAFG Clinical trial CAR T Cell Therapy [94]
CD19CART DMF936G Clinical trial CAR T Cell Therapy [95]
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⏷ Show the Full List of 101 Drug(s)
This Disease is Treated as An Indication in 12 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Aminopterin DMQ9RBV Withdrawn from market Small molecular drug [96]
LDI-200 DMKMTR7 Discontinued in Phase 3 NA [97]
Lintuzumab DMD39G4 Discontinued in Phase 2 Antibody [98]
CB-001 DM3OTSJ Discontinued in Phase 1/2 NA [99]
IDM-4 DMJE3SB Discontinued in Phase 1/2 NA [100]
Oncolysin M DM47ELH Discontinued in Phase 1 NA [101]
Ormaplatin DMG3C2G Discontinued in Phase 1 NA [102]
BE-22179 DM39SEK Terminated NA [105]
CMLVAX100 DMYJ2LO Terminated NA [106]
FR-900482 DMPEJGR Terminated Small molecular drug [107]
LN-040 DMZBTV8 Terminated NA [108]
Phosphonate DMAJ9ZD Terminated Small molecular drug [109]
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⏷ Show the Full List of 12 Drug(s)
This Disease is Treated as An Indication in 2 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
212Pb-labelled aCD37 DMLVADH Preclinical Radiopharmaceutical therapy agent [103]
MC-2001 DMBT2RJ Preclinical NA [104]
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This Disease is Treated as An Indication in 13 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
111In-labeled LFA-1 targeted imaging agent (lymphoma/leukemia), NuView/University of New Mexico DMBGQEH Investigative NA [25]
AL-18 DMX72V3 Investigative NA [25]
CEP-37309 DMCQE1D Investigative NA [25]
CTA-056 DMJ4EGI Investigative NA [25]
EB-1,2,3 mab DMYJDDA Investigative NA [25]
ELP-10 DMWKDMM Investigative NA [25]
EPZ-004777 DMLN4V5 Investigative Small molecular drug [110]
G-CSF DMVFDYU Investigative NA [111]
GenFusAb DMP01XD Investigative NA [25]
MDPTQ DML8NUY Investigative NA [25]
PV-327 DMVQ4WZ Investigative NA [25]
PYZD-4409 DME0NO8 Investigative Small molecular drug [112]
SNG-8033 DM0W54R Investigative NA [113]
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⏷ Show the Full List of 13 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 392 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
AKR1C3 TT5ZWB6 Limited Biomarker [114]
ANG TTURHFP Limited Altered Expression [115]
ANXA8 TTSW16P Limited Altered Expression [116]
APEX1 TTHGL48 Limited Genetic Variation [117]
BCL6 TTC9YX5 Limited Biomarker [118]
BRD4 TTSRAOU Limited Biomarker [119]
CASP5 TTWR48J Limited Genetic Variation [120]
CCL3 TT8I4WB Limited Biomarker [121]
CCR7 TT2GIDQ Limited Biomarker [122]
CD14 TT6I7DC Limited Biomarker [123]
CD200 TT0BE68 Limited Altered Expression [124]
CD28 TTQ13FT Limited Biomarker [125]
CD33 TTJVYO3 Limited Biomarker [126]
CD80 TT89Z17 Limited Altered Expression [127]
CEBPA TT5LWG1 Limited Genetic Variation [128]
CES1 TTMF541 Limited Biomarker [129]
CHEK1 TTTU902 Limited Biomarker [130]
CNTF TTGEM5Q Limited Biomarker [131]
CRLF2 TTRMZ0N Limited Genetic Variation [132]
CSF3R TTC70AJ Limited Biomarker [133]
CSPG4 TT7MYXI Limited Biomarker [134]
CXCR4 TTBID49 Limited Biomarker [135]
CYBB TT5T8MR Limited Biomarker [136]
CYP1B1 TTI84H7 Limited Altered Expression [137]
DCK TTJOCE4 Limited Altered Expression [138]
DDIT4 TTVEOY6 Limited Biomarker [139]
DGKA TTGL8F0 Limited Biomarker [140]
DICER1 TTTEOPU Limited Altered Expression [141]
DOT1L TTSZ8T1 Limited Altered Expression [142]
EBI3 TTJF68X Limited Biomarker [143]
EIF2AK2 TTXEZJ4 Limited Biomarker [144]
EP300 TTGH73N Limited Biomarker [145]
EPOR TTAUX24 Limited Genetic Variation [146]
EZH1 TTNJA0C Limited Posttranslational Modification [147]
EZH2 TT9MZCQ Limited Genetic Variation [148]
FCER2 TTCH6MU Limited Biomarker [149]
FLT4 TTDCBX5 Limited Biomarker [150]
FUT4 TTNV1KZ Limited Biomarker [151]
GEM TTAZF9M Limited Genetic Variation [152]
HDAC1 TT6R7JZ Limited Biomarker [153]
HLA-G TTLKFB3 Limited Altered Expression [154]
HNRNPA1 TTPJ9XK Limited Biomarker [155]
IL3RA TTENHJ0 Limited Altered Expression [156]
KIT TTX41N9 Limited Genetic Variation [157]
LIFR TTID542 Limited Altered Expression [158]
LYZ TTAOZBW Limited Biomarker [159]
MAP2K1 TTIDAPM Limited Biomarker [160]
MERTK TTO7LKR Limited Biomarker [161]
MIA TT5HNVS Limited Biomarker [162]
MPO TTVCZPI Limited Biomarker [163]
MSLN TT4RXME Limited Biomarker [164]
MYCBP TTVW4XU Limited Biomarker [165]
MYCN TT9JBY5 Limited Altered Expression [166]
NEDD8 TTNDC4K Limited Biomarker [167]
NQO1 TT8XK6L Limited Genetic Variation [168]
PIM1 TTTN5QW Limited Biomarker [169]
PLK1 TTH4IP0 Limited Biomarker [170]
PMEL TT8MK59 Limited Biomarker [171]
PML TTLH9NY Limited Biomarker [172]
PRMT5 TTR1D7X Limited Biomarker [173]
PTK2B TTTEFBV Limited Biomarker [174]
PTK7 TTXH2ZN Limited Biomarker [175]
PVRIG TTOGCNT Limited Altered Expression [176]
RARA TTW38KT Limited Genetic Variation [177]
RARG TT1Q3IE Limited Genetic Variation [177]
RNF6 TT4S09X Limited Biomarker [178]
ROCK1 TTZN7RP Limited Biomarker [179]
ROS1 TTSZ6Y3 Limited Biomarker [180]
RPS6KA3 TTUM2ZR Limited Biomarker [181]
SELE TT1PL7M Limited Biomarker [182]
SF3B1 TTL2WUI Limited Genetic Variation [183]
SPN TTOZAX0 Limited Biomarker [149]
TCL1A TTUKRDV Limited Genetic Variation [184]
TERF1 TT1Y6J2 Limited Altered Expression [185]
THPO TTCG5PE Limited Biomarker [186]
TMBIM6 TT7QSMG Limited Biomarker [187]
TRPM5 TT1N8F3 Limited Genetic Variation [188]
TSLP TTHMW3T Limited Altered Expression [189]
TYR TTULVH8 Limited Biomarker [190]
VTCN1 TTCK85E Limited Biomarker [191]
ZNF224 TT1CDXL Limited Biomarker [192]
CDA TTQ12RK Disputed Biomarker [193]
CXCL12 TT4UGTF Disputed Biomarker [135]
ID1 TTBXVDE Disputed Biomarker [194]
ABL2 TT1A6HL moderate Biomarker [195]
ACVRL1 TTGYPTC moderate Biomarker [196]
AIMP2 TTXWHGF moderate Biomarker [197]
BAK1 TTFM7V0 moderate Biomarker [198]
BCL2L2 TTQ79W8 moderate Biomarker [199]
CRK TTFEUYR moderate Biomarker [197]
CRTC2 TTFWETR moderate Biomarker [200]
DCLK1 TTOHTCY moderate Biomarker [201]
DHODH TTLVP78 moderate Altered Expression [202]
EHMT2 TTS6RZT moderate Biomarker [203]
FTO TTFW3BT moderate Biomarker [204]
GJB7 TTZ7POK moderate Biomarker [205]
GPRC6A TTI1PRE moderate Altered Expression [206]
IL24 TT1EPXZ moderate Biomarker [207]
ILK TT7ALZG moderate Biomarker [208]
ITGAM TTB69FJ moderate Biomarker [209]
KDM1A TTNR0UQ moderate Biomarker [210]
KMT5B TTJGV7F moderate Biomarker [211]
LTB4R TTN53ZF moderate Altered Expression [206]
LY9 TTZCL1U moderate Biomarker [212]
MAP2K7 TT6QY3J moderate Biomarker [213]
MAPK8 TT0K6EO moderate Biomarker [214]
MCM7 TT1RM3F moderate Altered Expression [215]
MPL TTIHYA4 moderate Biomarker [216]
MRGPRX1 TTIX6PK moderate Altered Expression [206]
MSI2 TTTXQF6 moderate Biomarker [217]
NRP1 TTIPJCB moderate Altered Expression [218]
NSD1 TTTSJ3H moderate Biomarker [219]
OXER1 TT7WBSV moderate Altered Expression [206]
PGD TTZ3IFB moderate Biomarker [220]
PHGDH TT8DRCK moderate Biomarker [221]
PIM3 TTCGOIN moderate Altered Expression [222]
PRTN3 TT5MLC4 moderate Biomarker [223]
RAB9A TT958S6 moderate Biomarker [224]
ROR2 TTUDPCI moderate Biomarker [225]
RPL15 TTQRVC9 moderate Biomarker [226]
RPSA TTLUW5B moderate Altered Expression [227]
RTN4R TTVRZUO moderate Biomarker [228]
SLC9A1 TTGSEFH moderate Biomarker [229]
SMYD3 TTKLJYX moderate Biomarker [230]
SSRP1 TTETDKQ moderate Biomarker [231]
ST8SIA4 TTDP8YM moderate Altered Expression [232]
TK1 TTP3QRF moderate Altered Expression [233]
TNFRSF18 TTG6LA7 moderate Biomarker [234]
TRIM28 TTQ2BKV moderate Biomarker [235]
USP10 TT5IH09 moderate Biomarker [236]
VDAC1 TTAMKGB moderate Biomarker [237]
XIAP TTK3WBU moderate Biomarker [238]
ABCC3 TTVLG21 Strong Biomarker [239]
ABCC4 TTUEAFL Strong Genetic Variation [240]
ADAM17 TT6AZXG Strong Biomarker [241]
ADAMTS1 TTS2TEI Strong Biomarker [242]
AICDA TTKRTP6 Strong Biomarker [243]
AKR1B1 TTFBNVI Strong Biomarker [244]
ALPI TTHYMUV Strong Biomarker [245]
ANK1 TTKFPMH Strong Genetic Variation [146]
AOX1 TT3MOS2 Strong Genetic Variation [246]
APCS TTB7VAT Strong Altered Expression [247]
ASPA TT6TLZP Strong Biomarker [248]
ASRGL1 TT4WT91 Strong Biomarker [249]
ATIC TT9NVXQ Strong Biomarker [250]
ATR TT8ZYBQ Strong Biomarker [251]
AURKA TTPS3C0 Strong Biomarker [252]
AURKB TT9RTBL Strong Altered Expression [253]
AXL TTZPY6J Strong Biomarker [254]
BCL11A TTR61MW Strong Biomarker [255]
BCL2A1 TTGT9C7 Strong Biomarker [256]
BPHL TTTZ3EU Strong Biomarker [257]
BRPF1 TTT46BN Strong Genetic Variation [258]
BSG TT5UJWD Strong Biomarker [259]
BST2 TT90BJT Strong Biomarker [260]
BTG1 TTL7N2W Strong Altered Expression [261]
BTK TTGM6VW Strong Biomarker [262]
BUB1 TT78309 Strong Biomarker [263]
CALR TTUZ7OA Strong Genetic Variation [264]
CASP2 TT12VNG Strong Biomarker [265]
CASP7 TTM7Y45 Strong Genetic Variation [266]
CASR TTBUYHA Strong Biomarker [267]
CBX7 TTBN3HC Strong Biomarker [268]
CCNA2 TTAMQ62 Strong Altered Expression [269]
CCR5 TTJIH8Q Strong Biomarker [135]
CCR6 TTFDB30 Strong Biomarker [270]
CD1A TTBGTFN Strong Altered Expression [271]
CD22 TTM6QSK Strong Biomarker [272]
CD27 TTDO1MV Strong Genetic Variation [273]
CD37 TTFCW29 Strong Biomarker [274]
CD3G TTV3XPL Strong Genetic Variation [275]
CD40LG TTIJP3Q Strong Biomarker [276]
CD5 TTEGYK1 Strong Biomarker [277]
CD70 TTNCIE0 Strong Biomarker [278]
CD79B TTBN5I7 Strong Biomarker [279]
CD9 TTZEIBV Strong Biomarker [280]
CDK1 TTH6V3D Strong Biomarker [281]
CDK2 TT7HF4W Strong Biomarker [282]
CDK6 TTO0FDJ Strong Biomarker [283]
CDK8 TTBJR4L Strong Biomarker [284]
CDK9 TT1LVF2 Strong Biomarker [285]
CEBPB TTUI35N Strong Altered Expression [286]
CLEC12A TT70N8V Strong Altered Expression [287]
CNTN2 TT2Z1WB Strong Genetic Variation [288]
COPS5 TTSTNJR Strong Biomarker [289]
CR1 TTEA8OW Strong Altered Expression [290]
CR2 TT0HUN7 Strong Altered Expression [291]
CREBBP TTFRCTK Strong Genetic Variation [292]
CSE1L TTTRULD Strong Biomarker [293]
CSF1 TT0IQER Strong Biomarker [294]
CSF1R TT7MRDV Strong Altered Expression [295]
CSF2RB TTPYS82 Strong Altered Expression [296]
CSNK2A1 TTER6YH Strong Biomarker [297]
CSNK2A2 TT7GR5W Strong Biomarker [297]
CTF1 TTXGTZU Strong Biomarker [298]
CTSG TTQAJF1 Strong Altered Expression [299]
CYP3A5 TTHS0OK Strong Genetic Variation [300]
DHFR TTYZVDJ Strong Altered Expression [301]
DLL1 TT9CFQD Strong Genetic Variation [302]
DNASE1 TTYWGOJ Strong Biomarker [303]
DNMT3A TTJUALD Strong Biomarker [304]
DNMT3B TT6VZ78 Strong Biomarker [305]
EBP TT4VQZX Strong Biomarker [306]
EIF4E TTZGCP6 Strong Biomarker [307]
ELANE TTPLTSQ Strong Altered Expression [308]
EPHA3 TTHS2LR Strong Biomarker [309]
F2RL3 TTD0652 Strong Altered Expression [310]
F8 TT1290U Strong Biomarker [311]
F9 TTFEZ5Q Strong Biomarker [312]
FANCF TTNZKFJ Strong Biomarker [313]
FCGR2B TT5RWKQ Strong Biomarker [314]
FCGRT TTKLPHO Strong Genetic Variation [315]
FDXR TT3W4IX Strong Biomarker [244]
FES TTLBY21 Strong Altered Expression [316]
FGF4 TTCEKVZ Strong Genetic Variation [317]
FMNL1 TTW20PQ Strong Biomarker [318]
FPR1 TT5Y4EM Strong Altered Expression [319]
FUS TTKGYZ9 Strong Biomarker [320]
FUT3 TTUPAD7 Strong Altered Expression [321]
GGH TTZJRL0 Strong Altered Expression [322]
GPR137 TTATO6X Strong Altered Expression [323]
GRB2 TTEYRJ9 Strong Biomarker [324]
GSTA1 TT4P8DE Strong Biomarker [325]
HAX1 TT21BYA Strong Genetic Variation [326]
HDAC7 TTMUEK1 Strong Altered Expression [327]
HDAC9 TT8M4E1 Strong Biomarker [328]
HDC TTV9GOF Strong Biomarker [329]
HMBS TTT0HW3 Strong Genetic Variation [275]
HMGB2 TTA78JQ Strong Biomarker [330]
HNF1A TT01M3K Strong Biomarker [331]
HOXA11 TTEX4ZA Strong Genetic Variation [332]
HOXA13 TTN26OM Strong Genetic Variation [332]
HOXA5 TTXSVQP Strong Biomarker [333]
HOXA7 TTMRE4Q Strong Genetic Variation [332]
HOXB13 TTZ6I58 Strong Genetic Variation [334]
HSF1 TTN6STZ Strong Biomarker [335]
HSP90AA1 TT78R5H Strong Altered Expression [336]
HSPB8 TTY0OJN Strong Altered Expression [337]
IAPP TTHN8EM Strong Biomarker [245]
IDH1 TTV2A1R Strong Genetic Variation [338]
IFNAR1 TTSYFMA Strong Genetic Variation [339]
IGFBP7 TTUQ01B Strong Biomarker [340]
IKZF3 TTCZVFZ Strong Genetic Variation [341]
IL11 TTGUYTR Strong Biomarker [131]
IL15 TTJFA35 Strong Biomarker [342]
IL15RA TTGN89I Strong Altered Expression [127]
IL1RL1 TT4GZA4 Strong Genetic Variation [343]
IL2 TTF89GD Strong Genetic Variation [344]
IL7 TT8FRMO Strong Biomarker [174]
IL7R TTAWI51 Strong Altered Expression [345]
INPP5D TTTP2Z1 Strong Genetic Variation [346]
IRAK1 TTXAJWN Strong Biomarker [347]
IRF1 TT4TU3L Strong Biomarker [348]
IRF8 TTHUBNK Strong Biomarker [349]
ITGA6 TT165T3 Strong Altered Expression [350]
JMJD1C TTBISK4 Strong Biomarker [351]
KAT6A TT6O1J0 Strong Genetic Variation [352]
KAT6B TTH4VJL Strong Genetic Variation [353]
KCNH1 TT9XKUC Strong Altered Expression [354]
KDM4C TTV8CRH Strong Biomarker [355]
KDM5A TTIG67W Strong Biomarker [356]
KDM5B TTCLI75 Strong Altered Expression [357]
KIR2DS1 TTVWAGF Strong Biomarker [358]
KIR3DL2 TTQH3N0 Strong Biomarker [358]
KLRK1 TTLRN4A Strong Biomarker [164]
KSR1 TTHL1TV Strong Biomarker [359]
LAMB3 TT2WOUQ Strong Altered Expression [360]
LCK TT860QF Strong Biomarker [361]
LIN28A TTO50LN Strong Biomarker [362]
LONP1 TTM1VPZ Strong Biomarker [169]
LRP6 TTSXOWE Strong Posttranslational Modification [363]
LTB4R2 TTVJX54 Strong Biomarker [364]
LTF TTSZDQU Strong Genetic Variation [365]
LTK TT1JZG6 Strong Altered Expression [366]
LYN TT1RWNJ Strong Altered Expression [367]
MAGEA1 TT63M7Q Strong Altered Expression [368]
MAP2K5 TTV3O87 Strong Biomarker [369]
MAPK7 TTU6FSC Strong Biomarker [369]
MAPK9 TT3IVG2 Strong Biomarker [370]
MARK2 TTAJ45Y Strong Biomarker [371]
MBP TT2RY5P Strong Genetic Variation [372]
MDM2 TT9TE0O Strong Altered Expression [373]
MLH1 TTISG27 Strong Genetic Variation [374]
MME TT5TKPM Strong Altered Expression [375]
MS4A1 TTUE541 Strong Biomarker [376]
MSH2 TTCAWRT Strong Altered Expression [377]
MSR1 TT2TDH9 Strong Biomarker [378]
MTR TTUTO39 Strong Genetic Variation [379]
MYB TT8V13P Strong Biomarker [380]
NAMPT TTD1WIG Strong Biomarker [381]
NCR1 TTQNRJM Strong Biomarker [382]
NME1 TTDY8JH Strong Biomarker [383]
NOTCH3 TTVX7IA Strong Biomarker [384]
NOTCH4 TTXDIK2 Strong Biomarker [385]
NR0B2 TT25A9Q Strong Altered Expression [386]
NR1I3 TTRANFM Strong Biomarker [267]
NR4A3 TTJQB49 Strong Biomarker [387]
NR5A2 TTAU3SY Strong Altered Expression [388]
P2RY1 TTA93TL Strong Biomarker [389]
PARG TT39J16 Strong Biomarker [257]
PAWR TT3I4WV Strong Altered Expression [310]
PAX5 TTA4REJ Strong Biomarker [390]
PBK TTMY6BZ Strong Altered Expression [391]
PDGFB TTQA6SX Strong Altered Expression [392]
PECAM1 TT4EZB2 Strong Genetic Variation [393]
PF4 TTSG7Q5 Strong Biomarker [394]
PHB TT6U071 Strong Altered Expression [395]
PHF8 TT81PFE Strong Biomarker [396]
PIM2 TT69J2Z Strong Biomarker [397]
PLA2R1 TTHKW7D Strong Posttranslational Modification [398]
PLK4 TTGPNZQ Strong Biomarker [399]
PPIB TT6ZFQ4 Strong Biomarker [400]
PPP5C TTTW7FJ Strong Biomarker [401]
PRAME TTPH7T0 Strong Biomarker [402]
PRG4 TTSKF4V Strong Biomarker [403]
PRKAR1A TTNAHEX Strong Biomarker [267]
PRMT1 TTVOJAI Strong Biomarker [404]
PSIP1 TTH9LDP Strong Biomarker [405]
PSMB6 TT8EPLT Strong Genetic Variation [302]
PTPN13 TT405FP Strong Altered Expression [406]
PTPN2 TTY8PUS Strong Biomarker [407]
PTPN6 TT369M5 Strong Altered Expression [386]
PTPRC TTUS45N Strong Altered Expression [209]
QPCT TTJ7YTV Strong Biomarker [408]
RALBP1 TTVSRUA Strong Biomarker [409]
REG3A TTL4H8N Strong Altered Expression [410]
ROBO4 TT3S9TY Strong Altered Expression [411]
ROR1 TTDEJAU Strong Biomarker [225]
RUNX2 TTD6SZ8 Strong Biomarker [412]
RUNX3 TTKCVO7 Strong Biomarker [413]
S100A8 TT4AF6N Strong Biomarker [414]
SCT TTOBVIN Strong Biomarker [415]
SELPLG TTS5K8U Strong Biomarker [416]
SEPTIN6 TTAGE7U Strong Biomarker [417]
SH3GL1 TTTYNAM Strong Biomarker [418]
SIRT6 TTUXYWF Strong Biomarker [419]
SLC22A1 TTM5Q4V Strong Biomarker [420]
SLC22A16 TTITAVR Strong Biomarker [421]
SLC23A2 TTOP832 Strong Biomarker [422]
SLC29A1 TTLXAKE Strong Altered Expression [423]
SLC46A1 TTY8Z2E Strong Altered Expression [424]
SLCO1B1 TTFGXEB Strong Genetic Variation [425]
SMPD2 TTE5VI6 Strong Altered Expression [426]
SMYD2 TT7YJFO Strong Biomarker [427]
SNAP25 TTYQWA0 Strong Genetic Variation [428]
SOCS3 TTI0ME6 Strong Altered Expression [429]
SPTBN1 TTS9BDA Strong Biomarker [430]
SRC TT6PKBN Strong Biomarker [431]
SRPK1 TTU3WV6 Strong Biomarker [432]
SRPK2 TTCZEJ9 Strong Altered Expression [433]
STC1 TTDLUER Strong Biomarker [434]
STMN1 TT7W5OT Strong Altered Expression [435]
SUV39H1 TTUWQTK Strong Biomarker [436]
TERF2 TT5XSLT Strong Biomarker [437]
TF TT8WXAV Strong Altered Expression [438]
TNFRSF10B TTW20TU Strong Biomarker [439]
TNFRSF13B TTL9OD4 Strong Biomarker [440]
TNFRSF17 TTZ3P4W Strong Biomarker [440]
TNFRSF9 TTPW9LJ Strong Biomarker [441]
TNFSF13 TTOI1RM Strong Biomarker [442]
TNK1 TTWS7I3 Strong Altered Expression [443]
TNK2 TTIET93 Strong Genetic Variation [444]
TOP1 TTGTQHC Strong Altered Expression [445]
TOP2A TTCGY2K Strong Biomarker [445]
TRB TT84HCW Strong Biomarker [446]
TRBC1 TT1DHW2 Strong Biomarker [447]
TRPV2 TTBECWA Strong Biomarker [448]
TRPV6 TTBK14N Strong Biomarker [449]
TUSC2 TTJ8O14 Strong Altered Expression [410]
UBE2E2 TTXJEOF Strong Altered Expression [322]
UGCG TTPHEX3 Strong Altered Expression [450]
USP7 TTXU3EQ Strong Biomarker [451]
WDR5 TT7OFWB Strong Biomarker [452]
WNT7A TT8NARC Strong Altered Expression [453]
WT1 TTZ8UT4 Strong Biomarker [454]
ZAP70 TTUMHT8 Strong Biomarker [455]
ABCB4 TTJUXV6 Definitive Altered Expression [456]
CD47 TT28S46 Definitive Biomarker [457]
DGKZ TTSBBXL Definitive Biomarker [458]
DLL4 TTV23LH Definitive Biomarker [459]
GRIA3 TT82EZV Definitive Altered Expression [460]
GRM3 TT8A9EF Definitive Altered Expression [460]
HIPK2 TTOB49C Definitive Genetic Variation [461]
JAK3 TTT7PJU Definitive Genetic Variation [462]
KIR2DL1 TT4UXPE Definitive Biomarker [463]
OPRK1 TTQW87Y Definitive Biomarker [464]
PIN1 TTJNTSI Definitive Altered Expression [465]
RIPK1 TTVJHX8 Definitive Biomarker [409]
SETD2 TTPC3H4 Definitive Biomarker [466]
SLC52A2 TT6TKEN Definitive Biomarker [371]
SLC5A6 TT61XTV Definitive Altered Expression [467]
USP1 TTG9MT5 Definitive Biomarker [468]
------------------------------------------------------------------------------------
⏷ Show the Full List of 392 DTT(s)
This Disease Is Related to 8 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCC11 DTWN7FC Limited Biomarker [469]
ATP7A DT0LT17 moderate Biomarker [470]
ABCB5 DTKVEXO Strong Biomarker [471]
SLC22A4 DT2EG60 Strong Biomarker [472]
SLC25A20 DTQOUM4 Strong Genetic Variation [473]
SLC29A2 DTW78DQ Strong Biomarker [474]
SLC39A8 DTLPQGT Strong Biomarker [475]
SLCO6A1 DTIFXNS Strong Genetic Variation [476]
------------------------------------------------------------------------------------
⏷ Show the Full List of 8 DTP(s)
This Disease Is Related to 19 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
FPGS DECWT2V Limited Genetic Variation [477]
SCLY DEH4TD6 Limited Biomarker [478]
ABO DESIA7R moderate Genetic Variation [479]
PARK7 DEPOVCH moderate Biomarker [480]
PON2 DEHJU7E moderate Altered Expression [481]
ACP3 DEDW5H6 Strong Biomarker [482]
AKR1C4 DEAJN47 Strong Biomarker [483]
ALDH1A1 DE2JP1Y Strong Altered Expression [484]
ASNS DEXISVQ Strong Genetic Variation [485]
CMPK1 DEMPH4I Strong Biomarker [486]
GSTM1 DEYZEJA Strong Genetic Variation [487]
GSTT1 DE3PKUG Strong Biomarker [487]
HK1 DEDMAGE Strong Biomarker [488]
HPRT1 DEVXTP5 Strong Genetic Variation [489]
MTRR DE6NIY9 Strong Genetic Variation [379]
NT5C2 DE1DOKJ Strong Genetic Variation [490]
SULT2A1 DE0P6LK Strong Genetic Variation [491]
THOP1 DE95LJC Strong Altered Expression [492]
TPMT DEFQ8VO Strong Altered Expression [493]
------------------------------------------------------------------------------------
⏷ Show the Full List of 19 DME(s)
This Disease Is Related to 563 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ABI1 OT5H4M62 Limited Altered Expression [494]
ADD1 OTTF68DC Limited Biomarker [495]
ARID2 OTIRJXWM Limited Biomarker [496]
ARSH OTG0X9UQ Limited Biomarker [324]
ASPG OT5E2EKR Limited Biomarker [497]
ATG5 OT4T5SMS Limited Biomarker [248]
ATN1 OTNZFLKY Limited Biomarker [498]
BLNK OTSSPF6F Limited Altered Expression [499]
CBFB OTIAC6W4 Limited Altered Expression [500]
CBX2 OTOQ5WS4 Limited Biomarker [328]
CD226 OT4UG0KB Limited Altered Expression [176]
CD48 OT83ZNPP Limited Biomarker [501]
CEBPE OTKZA25M Limited Biomarker [502]
CEBPZ OT11BATG Limited Biomarker [503]
CIAPIN1 OTWS90F9 Limited Biomarker [504]
CIP2A OTVS2GXA Limited Biomarker [505]
COBL OTTB4VFQ Limited Biomarker [506]
CRKL OTOYSD1R Limited Biomarker [507]
DCTN6 OTI8PIN9 Limited Biomarker [508]
DDX4 OTQOV093 Limited Altered Expression [509]
DDX41 OT6KEIHP Limited Genetic Variation [510]
DNTT OTFSEF12 Limited Posttranslational Modification [511]
ELL OTCBN5LF Limited Altered Expression [512]
ERG OTOTX9VU Limited Biomarker [513]
ESM1 OT331Y8V Limited Biomarker [514]
EXOSC5 OTADUQ7H Limited Altered Expression [515]
FAM168A OTDXQCS5 Limited Biomarker [516]
FBLIM1 OTFHXMON Limited Biomarker [517]
FIP1L1 OTF91GTL Limited Biomarker [518]
FLII OT7G9JG6 Limited Genetic Variation [393]
GADD45GIP1 OT4IZ4TP Limited Biomarker [519]
GDE1 OTU6FSBF Limited Biomarker [520]
GINS2 OT974IYI Limited Altered Expression [521]
GNB2 OT3JPRCQ Limited Genetic Variation [522]
GOPC OTRBGH71 Limited Biomarker [517]
GORASP1 OTQS91S7 Limited Posttranslational Modification [523]
HNRNPDL OTB3BFCV Limited Biomarker [524]
HOXB3 OT9UC5PE Limited Genetic Variation [146]
IFI27 OTI2XGIT Limited Biomarker [508]
IKZF1 OTCW1FKL Limited Genetic Variation [525]
IL18R1 OT83XMPQ Limited Biomarker [143]
INA OT1D33T4 Limited Biomarker [526]
KAT2A OTN0W2SW Limited Altered Expression [527]
KDM6A OTZM3MJJ Limited Biomarker [528]
KIR3DL1 OTPOSXFX Limited Genetic Variation [152]
KMT2B OTMMAZQX Limited Altered Expression [529]
KMT2D OTTVHCLY Limited Altered Expression [529]
KRT7 OTLT3JFN Limited Biomarker [478]
LAMP5 OTC672RM Limited Biomarker [530]
MEF2C OTZGF1Y5 Limited Biomarker [531]
MEN1 OTN6U6V0 Limited Biomarker [532]
MLLT1 OT41UZU5 Limited Biomarker [533]
MNDA OTCTKR47 Limited Altered Expression [534]
MRPL28 OT4LUTZU Limited Genetic Variation [535]
MRPL58 OTPTWLZY Limited Biomarker [536]
NBN OT73B5MD Limited Biomarker [537]
NCOA2 OTMQFPBB Limited Biomarker [538]
NNAT OTNRLO7G Limited Genetic Variation [539]
NSD3 OT3677ZG Limited Biomarker [540]
NUDC OT073JKX Limited Altered Expression [541]
NUDT21 OTZHKWAR Limited Biomarker [542]
NUTM1 OTONYC08 Limited Biomarker [543]
NXT1 OT0VO6AY Limited Genetic Variation [535]
OAZ1 OTPT0PKZ Limited Altered Expression [544]
OSCP1 OTZ4IFGJ Limited Biomarker [545]
PBX1 OTORABGO Limited Altered Expression [546]
PDCD5 OT6T2DDL Limited Biomarker [547]
PFDN5 OTTKPTUP Limited Biomarker [165]
PLAGL2 OT6AP4V2 Limited Altered Expression [548]
PSMA7 OTPHI6ST Limited Biomarker [549]
PSMD9 OT6Y5CC3 Limited Biomarker [508]
PVALB OTZW1WVQ Limited Biomarker [190]
RARS1 OTHPZ6JN Limited Biomarker [550]
RERE OT3G4GBZ Limited Biomarker [551]
RRAS OTBBF28C Limited Biomarker [552]
SBDS OTHDCCIB Limited Genetic Variation [553]
SEPTIN11 OTX2O0ZX Limited Biomarker [554]
SEPTIN9 OT1VMRFQ Limited Biomarker [555]
SERINC3 OTQ1LAJ1 Limited Biomarker [556]
SERINC5 OT3COPVF Limited Biomarker [556]
SH2B2 OTEDHHDH Limited Biomarker [557]
SIGIRR OTNC3XFD Limited Biomarker [558]
SIGLEC1 OTNWSQA9 Limited Altered Expression [559]
SMARCA1 OT0Y6PTU Limited Biomarker [560]
SSBP2 OTYG1G80 Limited Biomarker [561]
STAT5A OTBSJGN3 Limited Altered Expression [562]
STAT5B OTZVPEBT Limited Biomarker [563]
STIL OT9799VN Limited Biomarker [171]
SUB1 OTK71JYU Limited Genetic Variation [535]
TAF15 OTNE038N Limited Biomarker [564]
TCF4 OTB9ASTK Limited Biomarker [565]
TCHP OTVDMHSY Limited Biomarker [566]
TCL1B OT4CSO39 Limited Genetic Variation [184]
TFIP11 OT7NVSWU Limited Biomarker [567]
TICAM2 OTK7GIJ5 Limited Biomarker [508]
TLX3 OTBUHHK3 Limited Altered Expression [568]
TMED7 OTONO8E6 Limited Biomarker [508]
TNPO3 OTOT3HH0 Limited Biomarker [569]
TNR OTVJGAFN Limited Genetic Variation [570]
TP53BP2 OTOWJ2Y4 Limited Altered Expression [571]
TPD52 OTPKSK43 Limited Altered Expression [572]
FBXW11 OT2A6RLR Disputed Biomarker [573]
GATA2 OTBP2QQ2 Disputed Altered Expression [574]
LIN28B OTVWP0FN Disputed Biomarker [575]
MRGPRF OT74OZ2Z Disputed Biomarker [576]
RBFOX2 OTXY1WVH Disputed Biomarker [576]
TNFSF9 OTV9L89D Disputed Altered Expression [577]
ACD OTC54EPO moderate Biomarker [578]
ADCY7 OTAWMGP3 moderate Biomarker [579]
AFF4 OTTL5Y8R moderate Biomarker [580]
AHSA1 OTC7AFHT moderate Biomarker [197]
AQP8 OT99JKME moderate Biomarker [581]
ARHGEF1 OTXU4HBW moderate Biomarker [582]
ASH1L OTUT5NLJ moderate Biomarker [583]
ASXL2 OTNG4E2M moderate Genetic Variation [584]
ATXN1 OTQF0HNR moderate Biomarker [585]
B3GAT1 OTXFP98E moderate Biomarker [586]
CALM2 OTNYA92F moderate Biomarker [587]
CCNG2 OTII38K2 moderate Altered Expression [588]
CD200R1 OT65Q9M6 moderate Biomarker [125]
CD244 OTSMR85N moderate Biomarker [508]
CD99 OTPUZ5DE moderate Biomarker [589]
CDC73 OT6JASZ1 moderate Biomarker [590]
CEMP1 OTUEH5X5 moderate Altered Expression [591]
CEP152 OTOKZR9B moderate Biomarker [592]
CGAS OTJYIXNB moderate Biomarker [593]
CH25H OT9S2BSW moderate Altered Expression [594]
CIB1 OT4BVCRU moderate Altered Expression [595]
CRISPLD2 OTVSFHTL moderate Biomarker [596]
DACT1 OT19Z704 moderate Biomarker [597]
DCLRE1C OTW3KB1I moderate Biomarker [598]
DDX53 OTHK3EGZ moderate Biomarker [599]
DEFB1 OT5SV0E4 moderate Biomarker [600]
DNER OT2GH2E5 moderate Biomarker [601]
DOK1 OTGVRLW6 moderate Altered Expression [602]
DPY30 OTLHCJ6C moderate Biomarker [603]
DYNLRB2 OT1G3HAF moderate Biomarker [604]
EFNB2 OT0DCUOM moderate Biomarker [605]
ERCC5 OTQAKFJM moderate Genetic Variation [606]
EVPL OTZIAFEK moderate Biomarker [607]
FANCB OTMZTXB5 moderate Biomarker [608]
FANCD2 OTVEB5LF moderate Biomarker [313]
FH OTEQWU6Q moderate Biomarker [609]
GATA5 OTO81B63 moderate Biomarker [531]
GNB1 OTLL7L74 moderate Genetic Variation [610]
GOLGA6A OTHU9MRX moderate Biomarker [611]
GPR151 OT7EACU6 moderate Altered Expression [206]
GRAP2 OTS5NIZ3 moderate Biomarker [197]
GRB10 OTCKXGRC moderate Biomarker [612]
HMGB3 OTCJ2EZY moderate Biomarker [231]
HOXA10 OTB6GQ09 moderate Altered Expression [613]
IFIT3 OTPGHZB9 moderate Altered Expression [614]
IFNA1 OTPMKY0L moderate Biomarker [563]
INPP4B OTLROA7G moderate Biomarker [615]
JAM3 OTX0F9QL moderate Biomarker [616]
KLRF1 OTGHZ7FU moderate Biomarker [617]
KNL1 OT4Q3LHV moderate Biomarker [592]
LEF1 OTWS5I5H moderate Biomarker [565]
LETMD1 OTZTZ4RD moderate Biomarker [618]
LMO1 OTB59SKB moderate Biomarker [619]
MARVELD2 OTKB96L5 moderate Altered Expression [620]
MKRN2 OTDD1V3O moderate Altered Expression [621]
MLLT11 OTG5RVHC moderate Biomarker [622]
MRGPRX3 OTRKCCDS moderate Altered Expression [206]
MRGPRX4 OTOBHZVA moderate Altered Expression [206]
MTHFD2 OT1LQSGX moderate Biomarker [623]
MYCBP2 OTHODA1F moderate Biomarker [624]
MZF1 OTMVZCPW moderate Biomarker [625]
NDN OTYBYJ82 moderate Biomarker [626]
NECTIN2 OTIE0W6O moderate Altered Expression [627]
NKX2-3 OTF4IL5J moderate Biomarker [228]
NT5C1A OTS7UF36 moderate Genetic Variation [628]
NUDT15 OTX8SZOT moderate Genetic Variation [629]
PAQR3 OTTKJ9Y4 moderate Altered Expression [630]
PCLAF OTMVIOUU moderate Biomarker [590]
PDP1 OT82RTMT moderate Posttranslational Modification [631]
PICALM OTQVRPMQ moderate Biomarker [587]
PIK3R2 OTZSUQK5 moderate Altered Expression [632]
PKNOX1 OTUDMNHX moderate Biomarker [633]
POLDIP2 OT8SZSJ6 moderate Biomarker [197]
PPM1K OTNZ4N4E moderate Genetic Variation [634]
PRF1 OTFVXD7H moderate Genetic Variation [635]
PTPA OTRGFOI7 moderate Biomarker [636]
RAB27A OT9SQRWY moderate Biomarker [637]
RAG2 OTG9UYTW moderate Biomarker [638]
RALA OT734R7X moderate Biomarker [639]
RCBTB1 OTAYELI8 moderate Biomarker [611]
RNF19A OTKWCV80 moderate Biomarker [197]
SETBP1 OTKGCOSR moderate Genetic Variation [640]
SIGLEC10 OTD1WDQL moderate Altered Expression [641]
SLFN11 OTJWFPMY moderate Altered Expression [642]
SMARCA2 OTSGJ8SV moderate Genetic Variation [560]
SNAP91 OTE3EXWZ moderate Biomarker [587]
STUB1 OTSUYI9A moderate Biomarker [643]
TCF7L1 OTTUTF0O moderate Biomarker [644]
TJP2 OTQUY6BV moderate Biomarker [645]
TMEM30A OTR6N5J2 moderate Biomarker [646]
TRIM25 OT35SG1R moderate Biomarker [647]
A1CF OTJBKFA1 Strong Biomarker [248]
ABHD2 OTCRUOCS Strong Altered Expression [648]
ABR OTZQK8JF Strong Altered Expression [649]
ACP1 OTJ9CKLU Strong Altered Expression [650]
ADRM1 OTOU4EY6 Strong Altered Expression [651]
AFF1 OTT2C78E Strong Biomarker [652]
AGFG2 OTXQZHCR Strong Genetic Variation [653]
AHI1 OT8K2YWY Strong Biomarker [654]
AKAP13 OTOZAR14 Strong Biomarker [655]
ANKRD26 OT2ENKKV Strong Genetic Variation [656]
ANP32B OT3SQMLU Strong Biomarker [657]
ANXA7 OTLMD0TK Strong Biomarker [658]
APCDD1 OTV9AD0L Strong Biomarker [659]
APOBEC1 OTY8QX2R Strong Biomarker [660]
APOBEC3A OTYO6F5P Strong Biomarker [661]
APOBEC3B OTHLNI51 Strong Genetic Variation [662]
ARAP1 OTINOJJ7 Strong Altered Expression [319]
ARHGEF12 OTM2D3LT Strong Biomarker [663]
ARID4A OT1XKBZ0 Strong Biomarker [664]
ARID5B OTUQ4CQY Strong Genetic Variation [525]
ARIH2 OTJYJQJ8 Strong Biomarker [665]
ARR3 OTRZ00CH Strong Biomarker [267]
ASAP1 OT4DLRYY Strong Altered Expression [410]
ASAP2 OTGEXULW Strong Altered Expression [410]
ASPM OTKXQMNA Strong Biomarker [248]
ASXL1 OTX931AW Strong Genetic Variation [666]
ATF7IP OTU6ZA7F Strong Biomarker [667]
ATG3 OT28VBVK Strong Altered Expression [668]
B4GALNT2 OT85V4QV Strong Biomarker [669]
B4GALT1 OTBCXEK7 Strong Biomarker [670]
BAALC OTUZSRVF Strong Altered Expression [671]
BACH2 OT17GS18 Strong Genetic Variation [672]
BAG1 OTRQNIA4 Strong Biomarker [673]
BCAR1 OTKT2C2N Strong Biomarker [293]
BCL10 OT47MCLI Strong Altered Expression [674]
BCL3 OT1M5B95 Strong Biomarker [675]
BCOR OTG013AX Strong Biomarker [292]
BCORL1 OTPTFQN5 Strong Biomarker [676]
BRI3BP OTWCFPRM Strong Altered Expression [677]
C1QC OTLE5U1P Strong Genetic Variation [372]
C4BPA OTHNH6Y8 Strong Biomarker [678]
CAB39L OTQEBL0W Strong Genetic Variation [679]
CAMK4 OT47RDGV Strong Altered Expression [680]
CAMLG OTTSRY39 Strong Altered Expression [681]
CAPS OTC9GZ2M Strong Biomarker [682]
CASP14 OTKY93H9 Strong Genetic Variation [266]
CBFA2T2 OTNOIB23 Strong Altered Expression [683]
CBX8 OT4U5V1T Strong Biomarker [684]
CCDC51 OTOJNHNA Strong Biomarker [685]
CCNA1 OTX4HD45 Strong Altered Expression [686]
CD247 OT45FGUX Strong Biomarker [687]
CD79A OTOJC8DV Strong Biomarker [688]
CD82 OTH8MC64 Strong Biomarker [689]
CD8A OTDWQJXK Strong Biomarker [277]
CD8B OTMZ1T7J Strong Biomarker [277]
CDC34 OTNBK390 Strong Altered Expression [690]
CDKN2D OT2TTZPZ Strong Biomarker [312]
CDX4 OTD1SQKM Strong Altered Expression [691]
CHAF1B OTOMK4KH Strong Altered Expression [692]
CHD1 OT9R9G0H Strong Genetic Variation [693]
CHD5 OTS5EVHH Strong Altered Expression [694]
CHGB OT7SAQT2 Strong Biomarker [695]
CHMP5 OTQWZL6R Strong Altered Expression [696]
CKB OTUCKOTT Strong Altered Expression [697]
CLEC11A OT9KBH7C Strong Genetic Variation [698]
CMTM5 OTMS7NDP Strong Biomarker [699]
CNDP2 OTJR9436 Strong Altered Expression [138]
CNTNAP1 OT5Y03EU Strong Biomarker [700]
CSHL1 OTQKU2F5 Strong Altered Expression [701]
CTBP2 OTGZGT87 Strong Altered Expression [269]
CTNNA1 OTFC725Z Strong Posttranslational Modification [702]
CXADR OT9ZP02A Strong Biomarker [267]
CYTB OTAHB98A Strong Genetic Variation [703]
DACH1 OTMKNAGG Strong Biomarker [704]
DCC OT2C1SHW Strong Genetic Variation [705]
DCDC2 OTSUFH1H Strong Biomarker [706]
DLD OT378CU9 Strong Biomarker [707]
DMBT1 OTVNU9D9 Strong Genetic Variation [708]
DNA2 OT4DJFFU Strong Altered Expression [709]
DNAJC2 OT3JDA0R Strong Biomarker [710]
DOK2 OTIJ38UF Strong Altered Expression [711]
EAF1 OTN27MJW Strong Biomarker [712]
ECD OT3L3PCU Strong Altered Expression [713]
EFNB1 OT7JJW8P Strong Biomarker [714]
EGR3 OTGPJIRA Strong Biomarker [715]
EIF3A OTFABY9G Strong Biomarker [716]
EIF3D OTDOMP80 Strong Biomarker [717]
EIF6 OTEXMUED Strong Genetic Variation [553]
EMB OT67E3Q1 Strong Biomarker [718]
EMD OTR8ZANE Strong Biomarker [719]
ENOSF1 OT65D3ZK Strong Biomarker [720]
EPC2 OTTG0W9R Strong Biomarker [721]
ESAM OTF518AI Strong Biomarker [722]
ESPL1 OTMGEVOK Strong Altered Expression [723]
ETV7 OTIAADPA Strong Altered Expression [724]
EWSR1 OT7SRHV3 Strong Biomarker [725]
EXT1 OTRPALJK Strong Posttranslational Modification [726]
FBXO9 OTW5P5JF Strong Biomarker [727]
FCGR2C OTNLMNYB Strong Biomarker [314]
FCGR3B OTSLSPZG Strong Altered Expression [728]
FEN1 OT6QGG7O Strong Genetic Variation [729]
FLI1 OT0EV3LX Strong Genetic Variation [393]
FLNC OT3F8J6Y Strong Biomarker [730]
FLT3LG OTU0YGC4 Strong Biomarker [731]
FUBP1 OT77SC9N Strong Biomarker [732]
FUT1 OTODG57A Strong Biomarker [733]
FZD9 OTTZ9MKK Strong Genetic Variation [734]
GAB2 OTBFN705 Strong Genetic Variation [735]
GADD45A OTDRV63V Strong Biomarker [736]
GAS7 OT0M5TNY Strong Genetic Variation [737]
GEN1 OT1XFQXF Strong Biomarker [738]
GFI1 OT9HB9H8 Strong Biomarker [739]
GFI1B OTRDW8YO Strong Genetic Variation [740]
GIPC1 OTXLVCPJ Strong Altered Expression [741]
GLIS2 OTOUUV1X Strong Altered Expression [742]
GNL3 OTILGYO4 Strong Biomarker [743]
GPHN OTAKK1SV Strong Biomarker [744]
GPR180 OT2P0XNK Strong Biomarker [745]
GPRC5A OTPOCWR7 Strong Posttranslational Modification [746]
GSTK1 OTDNGWAF Strong Genetic Variation [476]
GYPA OTABU4YV Strong Genetic Variation [747]
GYPB OTESHUIX Strong Genetic Variation [747]
GYPE OTBHAG6A Strong Genetic Variation [747]
H2AX OT18UX57 Strong Posttranslational Modification [748]
H2AZ1 OT3KJJNQ Strong Biomarker [387]
H4C1 OTB71W46 Strong Altered Expression [749]
HERPUD1 OT9EROL6 Strong Genetic Variation [428]
HFE OTDD93KB Strong Genetic Variation [750]
HIP1 OT7AKCFQ Strong Altered Expression [751]
HLA-C OTV38BUJ Strong Biomarker [752]
HLA-DPB1 OTW8JHU2 Strong Genetic Variation [753]
HLF OTTRK9XN Strong Biomarker [754]
HMMR OT4M0JTZ Strong Biomarker [755]
HOXA1 OTMSOJ7D Strong Biomarker [756]
HOXA3 OTIX5XFB Strong Genetic Variation [332]
HOXA4 OTNVTQDT Strong Genetic Variation [332]
HOXA6 OTHJP8M2 Strong Genetic Variation [332]
HOXB1 OTGC0EKI Strong Altered Expression [757]
HOXB2 OTTD6HMV Strong Altered Expression [757]
HOXB4 OTH1HRW5 Strong Biomarker [758]
HOXB5 OTU74TB8 Strong Altered Expression [757]
HOXB6 OT3TFQ0U Strong Altered Expression [757]
HOXB7 OTC7WYU8 Strong Altered Expression [757]
HOXB8 OTKHOD17 Strong Altered Expression [757]
HOXB9 OTMVHQOU Strong Altered Expression [757]
HOXC10 OT5WF17M Strong Biomarker [759]
HOXD13 OTWSC8TF Strong Biomarker [760]
HSPA4L OT181WZB Strong Altered Expression [761]
HTN3 OTEUXA81 Strong Biomarker [762]
IER3 OTZJI5FZ Strong Altered Expression [763]
IGF2BP1 OT9G360P Strong Altered Expression [764]
IGF2BP2 OT4ZSEEE Strong Biomarker [765]
IGF2BP3 OTB97VIK Strong Biomarker [765]
IGFBP4 OT2HZRBD Strong Biomarker [766]
IL2RG OTRZ3OMY Strong Altered Expression [767]
IL3 OT0CQ35N Strong Biomarker [768]
INTS3 OT7NX4CD Strong Biomarker [385]
IRF4 OT1DHQ1P Strong Altered Expression [769]
JARID2 OT14UM8H Strong Biomarker [770]
KAT8 OT5LPQTR Strong Biomarker [771]
KIR2DS4 OT00N6UJ Strong Biomarker [772]
KIR2DS5 OTXLEN11 Strong Biomarker [773]
KLF1 OT1FK08U Strong Altered Expression [774]
KLF2 OTIP1UFX Strong Biomarker [298]
KMT2C OTC59BCO Strong Genetic Variation [775]
KRT20 OT4RB40L Strong Biomarker [376]
KYAT3 OTO4U2QK Strong Biomarker [776]
L3MBTL1 OT8M52QY Strong Genetic Variation [777]
LDB1 OT20EAPR Strong Biomarker [778]
LIG4 OT40DNXU Strong Altered Expression [779]
LIMS1 OT729S0T Strong Biomarker [780]
LLGL1 OTAIQSXZ Strong Biomarker [781]
LPXN OTUNV3CK Strong Biomarker [782]
LRSAM1 OTOKWR6C Strong Genetic Variation [783]
LXN OTZQ2M6Y Strong Posttranslational Modification [784]
MAGED4B OTO37U7W Strong Altered Expression [368]
MAGEF1 OTUU40U3 Strong Altered Expression [785]
MAGT1 OTQSAV5C Strong Biomarker [245]
MARCHF8 OTH7PNN2 Strong Genetic Variation [786]
MARCKSL1 OT13J2FM Strong Altered Expression [787]
MATK OTVOJJLJ Strong Biomarker [361]
MBD2 OTUQPP0R Strong Biomarker [788]
MBD3 OTRL76H5 Strong Biomarker [528]
MCM3 OTOOHQPM Strong Altered Expression [789]
ME2 OTO4LL76 Strong Biomarker [790]
MED15 OT0D0JVD Strong Posttranslational Modification [746]
MEF2D OT7CEIG0 Strong Genetic Variation [791]
MEIS2 OTG4ADLM Strong Biomarker [792]
METTL14 OT6TPQMH Strong Biomarker [582]
METTL3 OTSXP1M3 Strong Biomarker [793]
MLC1 OTCNZLSP Strong Posttranslational Modification [794]
MLF1 OTC5BKHU Strong Biomarker [795]
MLLT3 OTXH4DDG Strong Biomarker [796]
MLXIP OT30UNI7 Strong Genetic Variation [786]
MLXIPL OTR9MLLW Strong Biomarker [797]
MNAT1 OTXLOYCB Strong Biomarker [798]
MNX1 OTXP9FH1 Strong Biomarker [799]
MOV10 OT0KAY9G Strong Biomarker [800]
MRE11 OTGU8TZM Strong Biomarker [537]
MRPS30 OTDXIAGG Strong Altered Expression [410]
MRTFA OTCVXASM Strong Biomarker [531]
MS4A3 OT0CEJOO Strong Biomarker [801]
MSX1 OT5U41ZP Strong Biomarker [802]
MTPAP OT6HQ02S Strong Altered Expression [410]
MVP OTJGHJRB Strong Biomarker [803]
MYBL2 OTZ3JX8Q Strong Biomarker [804]
MYLIP OTL0PFGV Strong Genetic Variation [786]
MYOD1 OTV2S79X Strong Biomarker [531]
NANOG OTUEY1FM Strong Genetic Variation [805]
NCOR1 OT04XNOU Strong Genetic Variation [806]
NCOR2 OTY917X0 Strong Genetic Variation [807]
NCR3 OT20M764 Strong Biomarker [808]
NFAT5 OTKIE59S Strong Biomarker [809]
NFATC3 OTYOORME Strong Biomarker [809]
NLRP2 OTJA81JU Strong Genetic Variation [810]
NOG OTGRHHPG Strong Biomarker [811]
NOX5 OTHTH59G Strong Biomarker [812]
NRARP OTMYHUV2 Strong Biomarker [813]
NUDCD1 OT8DS3CX Strong Altered Expression [515]
NUP98 OTNT12G2 Strong Genetic Variation [814]
OLIG2 OTMCN6D3 Strong Altered Expression [815]
P2RX5 OTLBR20R Strong Altered Expression [388]
PACSIN2 OTC2R00C Strong Genetic Variation [816]
PAFAH1B1 OT9T2TCJ Strong Biomarker [817]
PAPOLA OTPHD65D Strong Altered Expression [410]
PARP4 OTXBK59G Strong Altered Expression [818]
PBX3 OT8WMVM4 Strong Genetic Variation [819]
PCDH10 OT2GIT0E Strong Posttranslational Modification [820]
PDAP1 OTJSWMOD Strong Altered Expression [410]
PDIK1L OTISF4KG Strong Genetic Variation [821]
PGP OT6QQ7OR Strong Biomarker [822]
PHB2 OTCAX3AW Strong Altered Expression [823]
PHC1 OT1JMX8U Strong Altered Expression [824]
PHF6 OT8DXI40 Strong Biomarker [568]
PI4K2B OT0D51QP Strong Biomarker [825]
PIAS1 OTZVAHZI Strong Biomarker [826]
PIP4K2A OTO9JO9U Strong Biomarker [827]
PKD2 OTIXBU8H Strong Biomarker [828]
PLEKHB1 OTC7TNAX Strong Biomarker [416]
PMAIP1 OTXEE550 Strong Biomarker [829]
PMEPA1 OTY8Z9UF Strong Altered Expression [830]
POGLUT1 OTDX7GZD Strong Altered Expression [831]
POU2F1 OTK7ELJ0 Strong Biomarker [420]
POU3F1 OTYARA94 Strong Biomarker [421]
POU4F1 OTMHYGWQ Strong Biomarker [832]
PPBP OT1FHGQS Strong Genetic Variation [833]
PPP2R5C OTF7CGO2 Strong Biomarker [834]
PRAM1 OTZN3DWD Strong Biomarker [835]
PRDM1 OTQLSVBS Strong Biomarker [836]
PRDM14 OTWZKY4L Strong Biomarker [837]
PRDM2 OT8L7CGX Strong Genetic Variation [838]
PRRX1 OTTZK5G8 Strong Biomarker [839]
PTPRA OTZA82J1 Strong Biomarker [803]
PTPRO OTFLKWOY Strong Genetic Variation [840]
QRSL1 OTJDU2UG Strong Biomarker [841]
RAB40B OTCA9ZF5 Strong Altered Expression [842]
RAB8A OTPB54Y3 Strong Biomarker [843]
RAC2 OTAOHFNH Strong Altered Expression [844]
RAD50 OTYMU9G1 Strong Biomarker [537]
RAD52 OT0OTDHI Strong Altered Expression [845]
RAG1 OTV131E4 Strong Biomarker [846]
RANGAP1 OTZGD3LJ Strong Altered Expression [847]
RAP1GAP OTC31ONQ Strong Biomarker [848]
RARRES1 OTETUPP5 Strong Posttranslational Modification [746]
RASGRF1 OTNWJ7EN Strong Altered Expression [849]
RBM15 OT8ZPGWF Strong Biomarker [850]
RBMXL1 OTMGCWWB Strong Biomarker [776]
RECQL4 OT59LSW7 Strong Biomarker [720]
RFC1 OT3L5PK3 Strong Biomarker [851]
RGCC OTYJMLWM Strong Altered Expression [852]
RGPD2 OTMUZ0HX Strong Genetic Variation [653]
RHOXF2 OTKQWLKZ Strong Biomarker [853]
RNASE3 OTVE2XD1 Strong Biomarker [854]
RNF20 OT9NK6ZT Strong Biomarker [855]
ROPN1L OTRWZJ68 Strong Biomarker [248]
RPN1 OTEG4KU9 Strong Genetic Variation [856]
RTEL1 OTI3PJCT Strong Biomarker [857]
RUVBL2 OTGWJ4T4 Strong Biomarker [858]
S100A11 OTI57KDN Strong Altered Expression [319]
SACM1L OT6ORKTD Strong Biomarker [859]
SALL4 OTC08PR5 Strong Altered Expression [860]
SAMHD1 OTBCIBC7 Strong Biomarker [861]
SEMG1 OT6Z4BPQ Strong Biomarker [695]
SERP2 OT5GA6JZ Strong Genetic Variation [862]
SERPINA4 OTBK0GG7 Strong Biomarker [863]
SET OTGYYQJO Strong Biomarker [505]
SETD1A OTVVWRIC Strong Biomarker [864]
SETX OTG3JNOQ Strong Biomarker [865]
SFRP5 OTLCVVSH Strong Biomarker [866]
SGK3 OTQ6QO99 Strong Biomarker [615]
SH3BP4 OTVIRKW7 Strong Biomarker [867]
SHB OTF2HSC0 Strong Biomarker [607]
SLC12A9 OTR7VRAK Strong Altered Expression [868]
SMAD5 OTQNSVCQ Strong Biomarker [869]
SMARCA5 OT5GR4Z2 Strong Biomarker [870]
SMARCD2 OTQTBWHW Strong Biomarker [871]
SMC4 OTEJE6AG Strong Biomarker [872]
SMCHD1 OTBV52DR Strong Altered Expression [873]
SMPX OTLSHGBF Strong Altered Expression [701]
SMYD5 OTE5VET6 Strong Altered Expression [874]
SNF8 OTRQA2AI Strong Biomarker [875]
SOAT1 OTB4Y5RJ Strong Biomarker [876]
SOCS5 OTN1ABYR Strong Altered Expression [877]
SON OT9VWV18 Strong Altered Expression [878]
SOX6 OTT0W0LE Strong Biomarker [879]
SOX7 OTOZOFAG Strong Altered Expression [880]
SP100 OTN8SD5W Strong Biomarker [881]
SPAG9 OT45AHMB Strong Genetic Variation [882]
SPANXB1 OTLMGC9T Strong Genetic Variation [883]
SPG7 OT8OY9ST Strong Biomarker [267]
SPI1 OTVCA1D0 Strong Altered Expression [884]
SPIB OTO4YKYI Strong Altered Expression [885]
SPINK6 OTYKZANJ Strong Biomarker [863]
SRI OT4R3EAC Strong Altered Expression [886]
STIM2 OTYNXAW0 Strong Biomarker [887]
SUV39H2 OTU0F4LL Strong Altered Expression [888]
SWT1 OTY4AFM1 Strong Biomarker [889]
TAL1 OTX4K6QZ Strong Altered Expression [890]
TALDO1 OTDKV2S2 Strong Genetic Variation [783]
TCF7 OT1ID822 Strong Altered Expression [891]
TCN2 OT41D0L3 Strong Altered Expression [892]
TEF OTY3LAD9 Strong Altered Expression [893]
TELO2 OT2YQ9L8 Strong Altered Expression [724]
TES OTL8PP6V Strong Biomarker [894]
TESC OTI8C76M Strong Altered Expression [895]
TFCP2 OTA246TE Strong Altered Expression [896]
TFPT OTM70AK1 Strong Altered Expression [897]
TFR2 OTMYCCEO Strong Altered Expression [898]
TGFBI OTR443C5 Strong Altered Expression [899]
THUMPD1 OTKU8KWH Strong Genetic Variation [900]
TIGAR OTR7NMRJ Strong Biomarker [901]
TLX1 OTVN0MNW Strong Biomarker [902]
TMEM132D OTV6I4Z0 Strong Genetic Variation [903]
TNFRSF10C OTVHOL9B Strong Posttranslational Modification [904]
TNFRSF10D OTOSRDJT Strong Genetic Variation [904]
TRAF1 OTTLM5RU Strong Biomarker [905]
TRIM13 OTQIUACB Strong Biomarker [267]
TRIM5 OTMZH7EJ Strong Biomarker [906]
TRIM62 OT15YO6N Strong Altered Expression [907]
TRPV5 OTWF4L0U Strong Biomarker [449]
TSC22D3 OT03UM03 Strong Biomarker [908]
TSGA10 OTIF1O1T Strong Altered Expression [909]
ARL6IP5 OTYZ6BEQ Definitive Genetic Variation [910]
CBFA2T3 OTOJ10S1 Definitive Biomarker [837]
CSNK2A3 OTZP4KZK Definitive Altered Expression [911]
DTX2 OT7QLDU4 Definitive Genetic Variation [912]
FCHSD2 OTKXLIJ6 Definitive Altered Expression [913]
FLVCR1 OT9XCFOC Definitive Genetic Variation [914]
FMOD OT9EJ5H8 Definitive Biomarker [915]
GPX3 OT6PK94R Definitive Posttranslational Modification [916]
HEMGN OTZPYUOY Definitive Altered Expression [917]
KDM2B OTDMCVW7 Definitive Biomarker [918]
KDM3B OTZU5J5S Definitive Biomarker [919]
LARP6 OTUQ9QS9 Definitive Altered Expression [920]
MACROD1 OTWFEVRW Definitive Biomarker [921]
OPN1LW OTFNUZ7O Definitive Genetic Variation [922]
PAG1 OTFOJUIQ Definitive Genetic Variation [922]
PCBP4 OTDLL4NB Definitive Genetic Variation [922]
POLM OT0SRIP4 Definitive Altered Expression [923]
PRDM16 OT0BGA27 Definitive Biomarker [924]
STAG2 OTR6X1Q7 Definitive Genetic Variation [925]
TEAD1 OTK6971C Definitive Biomarker [926]
TFPI2 OTZCRWOR Definitive Biomarker [926]
TLE1 OT50MRZ1 Definitive Biomarker [927]
TOX OTE8BL5Z Definitive Biomarker [928]
------------------------------------------------------------------------------------
⏷ Show the Full List of 563 DOT(s)

References

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5 ClinicalTrials.gov (NCT02421588) Clinical Trial of Lurbinectedin (PM01183) in Platinum Resistant Ovarian Cancer Patients. U.S. National Institutes of Health.
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8 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
9 ClinicalTrials.gov (NCT02039726) An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects. U.S. National Institutes of Health.
10 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040192)
11 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
12 ClinicalTrials.gov (NCT01309126) Study of Imprime PGG in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal Cancer. U.S. National Institutes of Health.
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16 ClinicalTrials.gov (NCT02040090) Phase II/III Study of the Safety and Effectiveness of HRIG With Co-administration of Active Rabies Vaccine in Healthy Subjects. U.S. National Institutes of Health.
17 ClinicalTrials.gov (NCT00058747) AG-858 in Patients Who Are Cytogenetically Positive After Treatment With Gleevec . U.S. National Institutes of Health.
18 ClinicalTrials.gov (NCT01206335) Open Label Study With OHR/AVR118 in Advanced Cancer Patients With Anorexia-Cachexia. U.S. National Institutes of Health.
19 ClinicalTrials.gov (NCT03312205) CAR-T Cells for Relapsed or Refractory Haematopoietic and Lymphoid Malignancies
20 ClinicalTrials.gov (NCT01626495) Phase I/IIA Study of CART19 Cells for Patients With Chemotherapy Resistant or Refractory CD19+ Leukemia and Lymphoma
21 ClinicalTrials.gov (NCT02071862) Study of the Glutaminase Inhibitor CB-839 in Solid Tumors. U.S. National Institutes of Health.
22 ClinicalTrials.gov (NCT02132624) CD19-targeting 3rd Generation CAR T Cells for Refractory B Cell Malignancy - a Phase I/IIa Trial.
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24 ClinicalTrials.gov (NCT01445587) A Study of GSK2110183 in Subjects With Proteasome Inhibitor Refractory Multiple Myeloma. U.S. National Institutes of Health.
25 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
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27 ClinicalTrials.gov (NCT00936468) Safety, Tolerability and Immunogenicity of Fluzone With and Without JVRS-100 in Elderly Subjects. U.S. National Institutes of Health.
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29 ClinicalTrials.gov (NCT00391066) Lumiliximab With Fludarabine, Cyclophosphamide, and Rituximab (FCR) Versus FCR Alone in Subjects With Relapsed Chronic Lymphocytic Leukemia (CLL). U.S. National Institutes of Health.
30 ClinicalTrials.gov (NCT01974479) Pilot Study of Redirected Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia. U.S. National Institutes of Health.
31 ClinicalTrials.gov (NCT01122784) Randomized Single-Blinded Study to Evaluate Safety and Immunogenicity of Recombinant Plague Vaccine With and Without Adjuvant. U.S. National Institutes of Health.
32 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019680)
33 ClinicalTrials.gov (NCT01266083) Trial of a WT-1 Analog Peptide Vaccine in Patients With Acute Myeloid Leukemia (AML) or Acute Lymphoblastic Leukemia (ALL). U.S. National Institutes of Health.
34 Development of a marrow transplant regimen for acute leukemia using targeted hematopoietic irradiation delivered by 131I-labeled anti-CD45 antibody, combined with cyclophosphamide and total body irradiation. Blood. 1995 Feb 15;85(4):1122-31.
35 ClinicalTrials.gov (NCT03098355) Interleukin-2 Following 4SCAR19/22 T Cells Targeting Refractory and/or Recurrent B Cell Malignancies
36 More Than 900 Medicines and Vaccines in Clinical Testing Offer New Hope in the Fight Against Cancer. Pharmaceutical Research and Manufacturers of America report. 2012.
37 ClinicalTrials.gov (NCT02954445) A Clinical Research of BCMA-Targeted CAR-T in B Cell Malignancies
38 ClinicalTrials.gov (NCT02937103) A Clinical Research of CD123-Targeted CAR-T in Myeloid Malignancies
39 ClinicalTrials.gov (NCT03638206) Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies
40 ClinicalTrials.gov (NCT02672501) A Study to Assess CD19-targeted Immunotherapy T Cells in Patients With Relapsed or Refractory CD19+ B Cell Leukemia
41 ClinicalTrials.gov (NCT02710149) A Clinical Research of CD20-Targeted CAR-T in B Cell Malignancies
42 ClinicalTrials.gov (NCT03262298) Anti-CD22 CAR-T Cell Therapy Targeting B Cell Malignancies
43 ClinicalTrials.gov (NCT02958410) A Clinical Research of CD30-Targeted CAR-T in Lymphocyte Malignancies
44 More Than 450 Medicines in Development for Rare Diseases. Pharmaceutical Research and Manufacturers of America report. 2013.
45 ClinicalTrials.gov (NCT02963038) CAR T Cells for Refractory B Cell Malignancy
46 ClinicalTrials.gov (NCT00285103) SPC2996 in Chronic Lymphocytic Leukaemia. U.S. National Institutes of Health.
47 ClinicalTrials.gov (NCT02933320) BI-1206 and an Anti-CD20 Antibody in Patients With CD32b Positive B-cell Lymphoma or Leukaemia. U.S. National Institutes of Health.
48 ClinicalTrials.gov (NCT03614858) CD19/CD22-targeted Chimeric Antigen Receptor Engineered T Cell (CART) in B-Cell Acute Lymphoblastic Leukemia.
49 ClinicalTrials.gov (NCT03398967) A Feasibility and Safety Study of Universal Dual Specificity CD19 and CD20 or CD22 CAR-T Cell Immunotherapy for Relapsed or Refractory Leukemia and Lymphoma
50 ClinicalTrials.gov (NCT02537977) CD19-directed CAR T Cells Therapy in Relapsed/Refractory B Cell Malignancy
51 ClinicalTrials.gov (NCT02935153) A Clinical Research of CD22-Targeted CAR-T in B Cell Malignancies
52 ClinicalTrials.gov (NCT02349698) A Clinical Research of CAR T Cells Targeting CD19 Positive Malignant B-cell Derived Leukemia and Lymphoma
53 ClinicalTrials.gov (NCT03142646) Safety and Efficacy Evaluation of IM19 CAR-T Cells
54 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800041076)
55 ClinicalTrials.gov (NCT00302861) A Study to Evaluate the Treatment of Previously Untreated B-Cell Chronic Lymphocytic Leukemia (B-CLL). U.S. National Institutes of Health.
56 ClinicalTrials.gov (NCT03594955) First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome. U.S. National Institutes of Health.
57 ClinicalTrials.gov (NCT03684889) CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma
58 ClinicalTrials.gov (NCT03166878) A Study Evaluating UCART019 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma
59 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033385)
60 ClinicalTrials.gov (NCT01287858) Study to Assess Safety, Tolerability, and Pharmacokinetics of Oral Doses for AC430 in Healthy Subjects. U.S. National Institutes of Health.
61 ClinicalTrials.gov (NCT02848911) Safety Study to Assess AFM11 in Patients With Relapsed or Refractory Adult B-precursor ALL. U.S. National Institutes of Health.
62 ClinicalTrials.gov (NCT02799550) Allogeneic CART-19 for Elderly Relapsed/Refractory CD19+ ALL
63 ClinicalTrials.gov (NCT03121625) CAR-T Therapy in Relapsed or Refractory Haematopoietic and Lymphoid Malignancies
64 ClinicalTrials.gov (NCT03271515) Immunotherapy With Bispecific CAR-T Cells for B-Cell Lymphoma, ALL and CLL
65 ClinicalTrials.gov (NCT01593696) Anti-CD19 White Blood Cells for Children and Young Adults With B Cell Leukemia or Lymphoma
66 ClinicalTrials.gov (NCT02546739) Immunotherapy With CD19 CAR T-cells for B-Cell Lymphoma, ALL and CLL
67 ClinicalTrials.gov (NCT03144583) Pilot Study on the Infusion of ARI-0001 Cells in Patients With CD19+ Leukemia or Lymphoma Refractory to Therapy
68 ClinicalTrials.gov (NCT02641002) A Study of CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS). U.S. National Institutes of Health.
69 ClinicalTrials.gov (NCT03407859) Sequential Treatment With CD20/CD22/CD10-CART After CD19-CART Treatment Base on MRD in Relapsed/Refractory B-ALL
70 ClinicalTrials.gov (NCT02529813) CD19+ CAR T Cells for Lymphoid Malignancies
71 ClinicalTrials.gov (NCT03463928) A Feasibility and Safety Study of Concomitant Therapy With Allo-CAR-T Cells and Allo-HSCT in Patients With Relapse or Refractory Leukemia
72 ClinicalTrials.gov (NCT03599375) Immunotherapy With CD19 CART-cells for B Cell Acute Lymphoblastic Leukemia
73 ClinicalTrials.gov (NCT03448393) CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
74 ClinicalTrials.gov (NCT03244306) A Phase 1 Study of CD22-CAR TCell Immunotherapy for CD22+ Leukemia and Lymphoma
75 ClinicalTrials.gov (NCT02284971) Pilot Study of SBRT and CDX-1127 in Prostate Cancer. U.S. National Institutes of Health.
76 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027936)
77 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031973)
78 ClinicalTrials.gov (NCT02374333) Pilot Study of Redirected Autologous T Cells Engineered to Contain Humanized Anti-CD19 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma Previously Treated With Cell Therapy
79 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007636)
80 ClinicalTrials.gov (NCT03383952) A Clinical Study of CD19 Targeted CAR-T for Patients With CD19+ Lymphoma and Leukemia
81 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800039238)
82 Clinical pipeline report, company report or official report of IN8bio.
83 J Clin Oncol 29: 2011 (suppl, abstr 6516).
84 ClinicalTrials.gov (NCT00313053) Study of mAb 216 With Chemotherapy for Treatment of Pediatric Relapsed or Refractory B-progenitor Acute Lymphoblastic Leukemia. U.S. National Institutes of Health.
85 ClinicalTrials.gov (NCT01976520) Vaccine Therapy for Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL). U.S. National Institutes of Health.
86 ClinicalTrials.gov (NCT03330691) A Feasibility and Safety Study of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy for CD19+CD22+ Leukemia and Lymphoma
87 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033111)
88 ClinicalTrials.gov (NCT00009841) Gene Therapy in Treating Patients With Advanced Head and Neck Cancer. U.S. National Institutes of Health.
89 ClinicalTrials.gov (NCT02194374) Autologous ROR1R-CAR-T Cells for Chronic Lymphocytic Leukemia (CLL)
90 Clinical pipeline report, company report or official report of Ziopharm Oncology.
91 ClinicalTrials.gov (NCT00526838) Study of XL228 Administered Intravenously to Subjects With Advanced Malignancies. U.S. National Institutes of Health.
92 ClinicalTrials.gov (NCT03624686) Production of Clinical-grade Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory B-cell Malignancies
93 ClinicalTrials.gov (NCT03302403) Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant Tumors
94 ClinicalTrials.gov (NCT03564977) CD19-targeted CAR-T Cell Therapy for MRD+ B-cell Malignancies After Autologous Stem Cell Transplantation
95 ClinicalTrials.gov (NCT02813837) Chimeric Antigen Receptor T Cells (CART) Therapy in Refractory/Relapsed B Cell Hematologic Malignancies
96 Drug information of Aminopterin, Health Canada, 2007.
97 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006739)
98 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7983).
99 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020067)
100 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014824)
101 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003885)
102 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000791)
103 Radiopharmaceutical therapy in cancer: clinical advances and challenges. Nat Rev Drug Discov. 2020 Sep;19(9):589-608.
104 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021088)
105 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004286)
106 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013916)
107 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003068)
108 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026172)
109 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004584)
110 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7377).
111 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4934).
112 The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma. Blood. 2010 Mar 18;115(11):2251-9.
113 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 620).
114 The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.Mutat Res. 2009 Mar 9;662(1-2):67-74. doi: 10.1016/j.mrfmmm.2008.12.010. Epub 2008 Dec 31.
115 Plexin-B2 Mediates Physiologic and Pathologic Functions of Angiogenin.Cell. 2017 Nov 2;171(4):849-864.e25. doi: 10.1016/j.cell.2017.10.005.
116 Expression and modulation of annexin VIII in human leukemia-lymphoma cell lines.Leuk Res. 1993 Nov;17(11):949-57. doi: 10.1016/0145-2126(93)90042-j.
117 Effects of polymorphic DNA genes involved in BER and caspase pathways on the clinical outcome of myeloproliferative neoplasms under treatment with hydroxyurea.Mol Med Rep. 2018 Dec;18(6):5243-5255. doi: 10.3892/mmr.2018.9535. Epub 2018 Oct 8.
118 BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia.J Exp Med. 2011 Oct 24;208(11):2163-74. doi: 10.1084/jem.20110304. Epub 2011 Sep 12.
119 BETP degradation simultaneously targets acute myelogenous leukemia stem cells and the microenvironment.J Clin Invest. 2019 Feb 21;129(5):1878-1894. doi: 10.1172/JCI120654. Print 2019 May 1.
120 Frameshift mutations in caspase-5 and other target genes in leukemia and lymphoma cell lines having microsatellite instability.Leuk Res. 2003 Apr;27(4):359-61. doi: 10.1016/s0145-2126(02)00215-1.
121 Osteolineage cells and regulation of the hematopoietic stem cell.Best Pract Res Clin Haematol. 2013 Sep;26(3):249-52. doi: 10.1016/j.beha.2013.10.004. Epub 2013 Oct 16.
122 Multiple myeloma secondary to acute lymphoblastic leukemia: A case report.Medicine (Baltimore). 2019 Jan;98(1):e14018. doi: 10.1097/MD.0000000000014018.
123 The outer membrane protein Tp92 of Treponema pallidum induces human mononuclear cell death and IL-8 secretion.J Cell Mol Med. 2018 Dec;22(12):6039-6054. doi: 10.1111/jcmm.13879. Epub 2018 Sep 14.
124 High CD200 expression is associated with poor prognosis in cytogenetically normal acute myeloid leukemia, even in FlT3-ITD-/NPM1+ patients.Leuk Res. 2017 Jul;58:31-38. doi: 10.1016/j.leukres.2017.04.001. Epub 2017 Apr 4.
125 A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia.Blood. 2017 Nov 30;130(22):2410-2419. doi: 10.1182/blood-2017-04-777052. Epub 2017 Oct 17.
126 Generation of Suicide Gene-Modified Chimeric Antigen Receptor-Redirected T-Cells for Cancer Immunotherapy.Methods Mol Biol. 2019;1895:57-73. doi: 10.1007/978-1-4939-8922-5_5.
127 IL-15/IL-15R/CD80-expressing AML cell vaccines eradicate minimal residual disease in leukemic mice.Blood Adv. 2018 Nov 27;2(22):3177-3192. doi: 10.1182/bloodadvances.2018019026.
128 CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex.Leukemia. 2019 Jul;33(7):1608-1619. doi: 10.1038/s41375-019-0382-3. Epub 2019 Jan 24.
129 Synergism between the mTOR inhibitor rapamycin and FAK down-regulation in the treatment of acute lymphoblastic leukemia.J Hematol Oncol. 2016 Feb 18;9:12. doi: 10.1186/s13045-016-0241-x.
130 Inhibition of the checkpoint kinase Chk1 induces DNA damage and cell death in human Leukemia and Lymphoma cells.Mol Cancer. 2014 Jun 10;13:147. doi: 10.1186/1476-4598-13-147.
131 Endoplasmic reticulum stress differentially modulates the IL-6 family of cytokines in murine astrocytes and macrophages.Sci Rep. 2019 Oct 17;9(1):14931. doi: 10.1038/s41598-019-51481-6.
132 Prognostic gene alterations and clonal changes in childhood B-ALL.Leuk Res. 2019 Aug;83:106159. doi: 10.1016/j.leukres.2019.05.009. Epub 2019 Jun 8.
133 A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia.Cancer Res. 2018 Dec 15;78(24):6762-6770. doi: 10.1158/0008-5472.CAN-18-1638. Epub 2018 Oct 22.
134 CSPG4-Specific CAR T Cells for High-Risk Childhood B Cell Precursor Leukemia.Int J Mol Sci. 2019 Jun 5;20(11):2764. doi: 10.3390/ijms20112764.
135 Blocking migration of regulatory T cells to leukemic hematopoietic microenvironment delays disease progression in mouse leukemia model.Cancer Lett. 2020 Jan 28;469:151-161. doi: 10.1016/j.canlet.2019.10.032. Epub 2019 Oct 24.
136 The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.Cell Rep. 2019 Apr 2;27(1):238-254.e6. doi: 10.1016/j.celrep.2019.03.009.
137 Polymorphisms in CYP1B1, CYP3A5, GSTT1, and SULT1A1 Are Associated with Early Age Acute Leukemia.PLoS One. 2015 May 18;10(5):e0127308. doi: 10.1371/journal.pone.0127308. eCollection 2015.
138 Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells.Pharmacol Res. 2007 Apr;55(4):343-9. doi: 10.1016/j.phrs.2007.01.003. Epub 2007 Jan 16.
139 RTP801 is a novel retinoic acid-responsive gene associated with myeloid differentiation.Exp Hematol. 2007 Apr;35(4):572-8. doi: 10.1016/j.exphem.2007.01.049.
140 Alternative splicing generates a diacylglycerol kinase transcript that acts as a dominant-negative modulator of superoxide production in localized aggressive periodontitis.J Periodontol. 2014 Jul;85(7):934-43. doi: 10.1902/jop.2013.130468. Epub 2013 Oct 30.
141 Overexpression of DICER1 induced by the upregulation of GATA1 contributes to the proliferation and apoptosis of leukemia cells.Int J Oncol. 2013 Apr;42(4):1317-24. doi: 10.3892/ijo.2013.1831. Epub 2013 Feb 19.
142 Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120Ubiquitination.Mol Cell. 2019 Jun 6;74(5):1010-1019.e6. doi: 10.1016/j.molcel.2019.03.029. Epub 2019 Apr 10.
143 c-MPL provides tumor-targeted T-cell receptor-transgenic T cells with costimulation and cytokine signals.Blood. 2017 Dec 21;130(25):2739-2749. doi: 10.1182/blood-2017-02-769463. Epub 2017 Oct 27.
144 Nuclear, not cytoplasmic, PKR maneuvers in AML.Blood. 2015 Sep 24;126(13):1523-4. doi: 10.1182/blood-2015-08-661421.
145 CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation.Epigenetics Chromatin. 2018 Jun 8;11(1):30. doi: 10.1186/s13072-018-0197-x.
146 FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.Blood. 2010 Nov 4;116(18):3622-6. doi: 10.1182/blood-2010-05-283648. Epub 2010 Jul 23.
147 Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia.Nat Commun. 2019 Nov 7;10(1):5051. doi: 10.1038/s41467-019-12960-6.
148 Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors.Cancer Cell. 2018 Feb 12;33(2):274-291.e8. doi: 10.1016/j.ccell.2018.01.006.
149 Intravascular Colonization of Kaposi Sarcoma: Expanding the Spectrum of Specific Infiltrates of B-Cell Chronic Lymphocytic Leukemia.Am J Dermatopathol. 2019 Dec;41(12):940-944. doi: 10.1097/DAD.0000000000001481.
150 DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4).BMC Cancer. 2012 Jan 17;12:19. doi: 10.1186/1471-2407-12-19.
151 MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/-catenin pathway in acute myeloid leukemia.J Exp Clin Cancer Res. 2019 May 16;38(1):200. doi: 10.1186/s13046-019-1179-y.
152 Natural Killer Cells Offer Differential Protection From Leukemia in Chinese Southern Han.Front Immunol. 2019 Jul 16;10:1646. doi: 10.3389/fimmu.2019.01646. eCollection 2019.
153 HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.Leukemia. 2018 Jan;32(1):49-60. doi: 10.1038/leu.2017.174. Epub 2017 Jun 5.
154 HLA-G peptide preferences change in transformed cells: impact on the binding motif.Immunogenetics. 2018 Aug;70(8):485-494. doi: 10.1007/s00251-018-1058-2. Epub 2018 Mar 30.
155 Chronic myelogenous leukemia cells remodel the bone marrow niche via exosome-mediated transfer of miR-320.Theranostics. 2019 Jul 28;9(19):5642-5656. doi: 10.7150/thno.34813. eCollection 2019.
156 Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias.Blood Adv. 2019 Dec 10;3(23):3962-3967. doi: 10.1182/bloodadvances.2019000731.
157 Gene mutation profile and risk stratification in AML1ETOpositive acute myeloid leukemia based on nextgeneration sequencing.Oncol Rep. 2019 Dec;42(6):2333-2344. doi: 10.3892/or.2019.7375. Epub 2019 Oct 15.
158 LIFR-CT3 induces differentiation of a human acute myelogenous leukemia cell line HL-60 by suppressing miR-155 expression through the JAK/STAT pathway.Leuk Res. 2014 Oct;38(10):1237-44. doi: 10.1016/j.leukres.2014.07.004. Epub 2014 Jul 22.
159 ORP4L Extracts and Presents PIP(2) from Plasma Membrane for PLC3 Catalysis: Targeting It Eradicates Leukemia Stem Cells.Cell Rep. 2019 Feb 19;26(8):2166-2177.e9. doi: 10.1016/j.celrep.2019.01.082.
160 Oral MEK 1/2 Inhibitor Trametinib in Combination With AKT Inhibitor GSK2141795 in Patients With Acute Myeloid Leukemia With RAS Mutations: A Phase II Study.Clin Lymphoma Myeloma Leuk. 2019 Jul;19(7):431-440.e13. doi: 10.1016/j.clml.2019.03.015. Epub 2019 Mar 26.
161 MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity.JCI Insight. 2018 Nov 2;3(21):e97941. doi: 10.1172/jci.insight.97941.
162 Effect of a nutrient mixture on matrix metalloproteinase-9 dimers in various human cancer cell lines.Int J Oncol. 2014 Mar;44(3):986-92. doi: 10.3892/ijo.2013.2235. Epub 2013 Dec 30.
163 Flow cytometric false myeloperoxidase-positive childhood B-lineage acute lymphoblastic leukemia.Cytometry B Clin Cytom. 2018 May;94(3):477-483. doi: 10.1002/cyto.b.21613. Epub 2018 Jan 17.
164 CAR-T "the living drugs", immune checkpoint inhibitors, and precision medicine: a new era of cancer therapy.J Hematol Oncol. 2019 Nov 8;12(1):113. doi: 10.1186/s13045-019-0819-1.
165 MM-1, a c-Myc-binding protein, is a candidate for a tumor suppressor in leukemia/lymphoma and tongue cancer.J Biol Chem. 2001 Nov 30;276(48):45137-44. doi: 10.1074/jbc.M106127200. Epub 2001 Sep 20.
166 L-myc and N-myc in hematopoietic malignancies.Leuk Lymphoma. 1993 Oct;11(3-4):197-205. doi: 10.3109/10428199309086996.
167 The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors.Cell Cycle. 2019 Sep;18(18):2307-2322. doi: 10.1080/15384101.2019.1646068. Epub 2019 Jul 26.
168 Effects of the NQO1 609C>T polymorphism on leukemia susceptibility: evidence from a meta-analysis.Asian Pac J Cancer Prev. 2013;14(9):5311-6. doi: 10.7314/apjcp.2013.14.9.5311.
169 Understanding PIM-1 kinase inhibitor interactions with free energy simulation.Phys Chem Chem Phys. 2019 Apr 3;21(14):7544-7558. doi: 10.1039/c9cp00070d.
170 Targeted Polo-like Kinase Inhibition Combined With Aurora Kinase Inhibition in Pediatric Acute Leukemia Cells.J Pediatr Hematol Oncol. 2019 Aug;41(6):e359-e370. doi: 10.1097/MPH.0000000000001416.
171 SIL-TAL1 rearrangement is related with poor outcome: a study from a Chinese institution.PLoS One. 2013 Sep 9;8(9):e73865. doi: 10.1371/journal.pone.0073865. eCollection 2013.
172 Promyelocytic leukemia protein in mesenchymal stem cells is essential for leukemia progression.Ann Hematol. 2018 Oct;97(10):1749-1755. doi: 10.1007/s00277-018-3463-x. Epub 2018 Aug 1.
173 Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation.Eur J Med Chem. 2019 Feb 15;164:317-333. doi: 10.1016/j.ejmech.2018.12.065. Epub 2018 Dec 26.
174 STAT5 is essential for IL-7-mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells.Blood Adv. 2018 Sep 11;2(17):2199-2213. doi: 10.1182/bloodadvances.2018021063.
175 DNA Aptamers in the Detection of Leukemia Cells by the Thickness Shear Mode Acoustics Method.Chemphyschem. 2019 Feb 18;20(4):545-554. doi: 10.1002/cphc.201801126. Epub 2019 Feb 6.
176 DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy.Cancers (Basel). 2019 Jun 23;11(6):877. doi: 10.3390/cancers11060877.
177 RARA and RARG gene downregulation associated with EZH2 mutation in acute promyelocytic-like morphology leukemia.Hum Pathol. 2018 Oct;80:82-86. doi: 10.1016/j.humpath.2018.02.023. Epub 2018 Mar 10.
178 Ring finger protein 6 promotes breast cancer cell proliferation by stabilizing estrogen receptor alpha.Oncotarget. 2017 Mar 21;8(12):20103-20112. doi: 10.18632/oncotarget.15384.
179 The cyclohexene derivative MC-3129 exhibits antileukemic activity via RhoA/ROCK1/PTEN/PI3K/Akt pathway-mediated mitochondrial translocation of cofilin.Cell Death Dis. 2018 May 29;9(6):656. doi: 10.1038/s41419-018-0689-4.
180 Tunicamycin promotes apoptosis in leukemia cells through ROS generation and downregulation of survivin expression.Apoptosis. 2015 Aug;20(8):1087-98. doi: 10.1007/s10495-015-1135-z.
181 p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.Blood. 2011 Jun 23;117(25):6885-94. doi: 10.1182/blood-2010-10-315721. Epub 2011 Apr 28.
182 p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription.Oncotarget. 2017 Jan 3;8(1):1678-1687. doi: 10.18632/oncotarget.13779.
183 Prognostic value and clinical feature of SF3B1 mutations in myelodysplastic syndromes: A meta-analysis.Crit Rev Oncol Hematol. 2019 Jan;133:74-83. doi: 10.1016/j.critrevonc.2018.07.013. Epub 2018 Aug 3.
184 PI3K p110 inactivation antagonizes chronic lymphocytic leukemia and reverses T cell immune suppression.J Clin Invest. 2019 Jan 2;129(1):122-136. doi: 10.1172/JCI99386. Epub 2018 Nov 19.
185 Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia.Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24252-24258. doi: 10.1073/pnas.1913695116. Epub 2019 Nov 13.
186 Megakaryocyte and polyploidization.Exp Hematol. 2018 Jan;57:1-13. doi: 10.1016/j.exphem.2017.10.001. Epub 2017 Oct 27.
187 Characterization of BAX inhibitor-1 as a novel leukemia-associated antigen.Leukemia. 2009 Oct;23(10):1818-24. doi: 10.1038/leu.2009.138. Epub 2009 Jul 16.
188 Expression and function of the transient receptor potential ion channel family in the hematologic malignancies.Curr Mol Pharmacol. 2013 Nov;6(3):137-48. doi: 10.2174/187446720603140415215431.
189 A novel xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis.Haematologica. 2016 Apr;101(4):417-26. doi: 10.3324/haematol.2015.125336. Epub 2015 Nov 26.
190 Effect of tyrosinase and caffeic acid crosslinking of turbot parvalbumin on the digestibility, and release of mediators and cytokines from activated RBL-2H3 cells.Food Chem. 2019 Dec 1;300:125209. doi: 10.1016/j.foodchem.2019.125209. Epub 2019 Jul 20.
191 Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality.JCI Insight. 2019 Oct 3;4(19):e127716. doi: 10.1172/jci.insight.127716.
192 Role of ZNF224 in cell growth and chemoresistance of chronic lymphocitic leukemia.Hum Mol Genet. 2017 Jan 15;26(2):344-353. doi: 10.1093/hmg/ddw427.
193 CDA gene silencing regulated the proliferation and apoptosis of chronic myeloid leukemia K562 cells.Cancer Cell Int. 2018 Jul 9;18:96. doi: 10.1186/s12935-018-0587-y. eCollection 2018.
194 Differential role of Id1 in MLL-AF9-driven leukemia based on cell of origin.Blood. 2016 May 12;127(19):2322-6. doi: 10.1182/blood-2015-11-677708. Epub 2016 Mar 4.
195 High Expression of ABL2 Suppresses Apoptosis in Gastric Cancer.Dig Dis Sci. 2018 Sep;63(9):2294-2300. doi: 10.1007/s10620-018-5111-7. Epub 2018 May 16.
196 Synergistic killing effects of homoharringtonine and arsenic trioxide on acute myeloid leukemia stem cells and the underlying mechanisms. J Exp Clin Cancer Res. 2019 Jul 15;38(1):308. doi: 10.1186/s13046-019-1295-8.
197 Quinacrine induces apoptosis in human leukemia K562 cells via p38 MAPK-elicited BCL2 down-regulation and suppression of ERK/c-Jun-mediated BCL2L1 expression.Toxicol Appl Pharmacol. 2015 Apr 1;284(1):33-41. doi: 10.1016/j.taap.2015.02.005. Epub 2015 Feb 12.
198 Cigarette smoke induces rat testicular injury via mitochondrial apoptotic pathway.Mol Reprod Dev. 2017 Oct;84(10):1053-1065. doi: 10.1002/mrd.22863.
199 Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.Clin Cancer Res. 2012 Feb 1;18(3):783-95. doi: 10.1158/1078-0432.CCR-11-1166. Epub 2011 Dec 15.
200 Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia.Blood. 2017 Jan 12;129(2):177-187. doi: 10.1182/blood-2016-05-707653. Epub 2016 Oct 24.
201 Doublecortin-Like Kinase 1 (DCLK1) Regulates B Cell-Specific Moloney Murine Leukemia Virus Insertion Site 1 (Bmi-1) and is Associated with Metastasis and Prognosis in Pancreatic Cancer.Cell Physiol Biochem. 2018;51(1):262-277. doi: 10.1159/000495228. Epub 2018 Nov 19.
202 Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.Cell. 2016 Sep 22;167(1):171-186.e15. doi: 10.1016/j.cell.2016.08.057. Epub 2016 Sep 15.
203 Transcriptional Selectivity of Epigenetic Therapy in Cancer.Cancer Res. 2017 Jan 15;77(2):470-481. doi: 10.1158/0008-5472.CAN-16-0834. Epub 2016 Nov 22.
204 The role of chlorine atom on the binding between 2-phenyl-1H-benzimidazole analogues and fat mass and obesity-associated protein.J Mol Recognit. 2019 Jun;32(6):e2774. doi: 10.1002/jmr.2774. Epub 2018 Dec 21.
205 Cx25 contributes to leukemia cell communication and chemosensitivity.Oncotarget. 2015 Oct 13;6(31):31508-21. doi: 10.18632/oncotarget.5226.
206 Visualization of ligand-induced G(i)-protein activation in chemotaxing cells.FASEB J. 2017 Mar;31(3):910-919. doi: 10.1096/fj.201601102R. Epub 2016 Nov 23.
207 Immunogenicity moderation effect of interleukin-24 on myelogenous leukemia cells.Anticancer Drugs. 2018 Apr;29(4):353-363. doi: 10.1097/CAD.0000000000000606.
208 Mechanisms and consequences of constitutive activation of integrin-linked kinase in acute myeloid leukemia.Cytokine Growth Factor Rev. 2018 Oct;43:1-7. doi: 10.1016/j.cytogfr.2018.06.001. Epub 2018 Jun 7.
209 Leukemia growth is inhibited by benzoxime without causing any harmful effect in rats bearing RBL-1 enotransplants.Oncol Lett. 2019 Feb;17(2):1934-1938. doi: 10.3892/ol.2018.9783. Epub 2018 Nov 30.
210 ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.Cancer Cell. 2018 Mar 12;33(3):495-511.e12. doi: 10.1016/j.ccell.2018.02.002. Epub 2018 Mar 1.
211 Suv4-20h1 promotes G1 to S phase transition by downregulating p21(WAF1/CIP1) expression in chronic myeloid leukemia K562 cells.Oncol Lett. 2018 May;15(5):6123-6130. doi: 10.3892/ol.2018.8092. Epub 2018 Feb 21.
212 CD229 is expressed on the surface of plasma cells carrying an aberrant phenotype and chemotherapy-resistant precursor cells in multiple myeloma.Hum Vaccin Immunother. 2015;11(7):1606-11. doi: 10.1080/21645515.2015.1046658.
213 Doubling Down on Mutant RAS Can MEK or Break Leukemia.Cell. 2017 Feb 23;168(5):749-750. doi: 10.1016/j.cell.2017.02.013.
214 HMGB1 regulates erastin-induced ferroptosis via RAS-JNK/p38 signaling in HL-60/NRAS(Q61L) cells.Am J Cancer Res. 2019 Apr 1;9(4):730-739. eCollection 2019.
215 RNAi-mediated knockdown of MCM7 gene on CML cells and its therapeutic potential for leukemia.Med Oncol. 2017 Feb;34(2):21. doi: 10.1007/s12032-016-0878-x. Epub 2017 Jan 5.
216 c-MPL Is a Candidate Surface Marker and Confers Self-Renewal, Quiescence, Chemotherapy Resistance, and Leukemia Initiation Potential in Leukemia Stem Cells.Stem Cells. 2018 Nov;36(11):1685-1696. doi: 10.1002/stem.2897. Epub 2018 Sep 5.
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481 The anti-apoptotic PON2 protein is Wnt/-catenin-regulated and correlates with radiotherapy resistance in OSCC patients.Oncotarget. 2016 Aug 9;7(32):51082-51095. doi: 10.18632/oncotarget.9013.
482 5'-nucleotidase activity in lymphocytes from patients affected by B-cell chronic lymphocytic leukemia.Clin Biochem. 1998 Jun;31(4):269-72. doi: 10.1016/s0009-9120(98)00017-4.
483 Association of MTG8 (ETO/CDR), a leukemia-related protein, with serine/threonine protein kinases and heat shock protein HSP90 in human hematopoietic cell lines.Jpn J Cancer Res. 1999 Jan;90(1):60-8. doi: 10.1111/j.1349-7006.1999.tb00666.x.
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485 Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia.Mol Cancer Ther. 2019 Sep;18(9):1587-1592. doi: 10.1158/1535-7163.MCT-18-1329. Epub 2019 Jun 17.
486 Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells.Int J Mol Med. 2001 Sep;8(3):273-8.
487 Effects of GST null genotypes on individual susceptibility to leukemia: A meta-analysis.Exp Mol Pathol. 2019 Jun;108:137-142. doi: 10.1016/j.yexmp.2019.01.004. Epub 2019 Jan 17.
488 Glycolytic Enzyme PKM2 Mediates Autophagic Activation to Promote Cell Survival in NPM1-Mutated Leukemia.Int J Biol Sci. 2019 Mar 1;15(4):882-894. doi: 10.7150/ijbs.30290. eCollection 2019.
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490 Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.Leukemia. 2018 Jun;32(6):1393-1403. doi: 10.1038/s41375-018-0073-5. Epub 2018 Feb 25.
491 Cloned hst gene from normal human leukocyte DNA transforms NIH3T3 cells.Biochem Biophys Res Commun. 1988 Mar 30;151(3):965-72. doi: 10.1016/s0006-291x(88)80460-1.
492 Retroviral integration site analysis identifies ICSBP as a collaborating tumor suppressor gene in NUP98-TOP1-induced leukemia.Exp Hematol. 2006 Sep;34(9):1192-201. doi: 10.1016/j.exphem.2006.04.020.
493 Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait.Clin Pharmacol Ther. 2017 Mar;101(3):373-381. doi: 10.1002/cpt.463. Epub 2016 Nov 18.
494 Low expression of Abelson interactor-1 is linked to acquired drug resistance in Bcr-Abl-induced leukemia.Leukemia. 2014 Nov;28(11):2165-77. doi: 10.1038/leu.2014.120. Epub 2014 Apr 4.
495 T-cell acute lymphoblastic leukemia with add(1)(p36) and del(12)(p11) following acute myelocytic leukemia with partial deletion of 9p.Cancer Genet Cytogenet. 2004 Apr 1;150(1):62-5. doi: 10.1016/j.cancergencyto.2003.08.003.
496 The chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis.J Hematol Oncol. 2018 Feb 26;11(1):27. doi: 10.1186/s13045-018-0567-7.
497 Acquired Hypofibrinogenemia Before Asparaginase Exposure During Induction Therapy for Pediatric Acute Lymphoblastic Leukemia: A Report of 2 Cases and Review of the Literature.J Pediatr Hematol Oncol. 2018 Oct;40(7):e470-e472. doi: 10.1097/MPH.0000000000001114.
498 An ARC-Regulated IL1/Cox-2/PGE2/-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML.Cancer Res. 2019 Mar 15;79(6):1165-1177. doi: 10.1158/0008-5472.CAN-18-0921. Epub 2019 Jan 23.
499 SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells.Oncogene. 2006 Aug 24;25(37):5180-6. doi: 10.1038/sj.onc.1209520. Epub 2006 Apr 24.
500 CBF-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.Cell. 2018 Jun 28;174(1):172-186.e21. doi: 10.1016/j.cell.2018.05.048.
501 TGF- regulated leukemia cell susceptibility against NK targeting through the down-regulation of the CD48 expression.Immunobiology. 2019 Sep;224(5):649-658. doi: 10.1016/j.imbio.2019.07.002. Epub 2019 Aug 9.
502 Association of genetic variation in IKZF1, ARID5B, CDKN2A, and CEBPE with the risk of acute lymphoblastic leukemia in Tunisian children and their contribution to racial differences in leukemia incidence.Pediatr Hematol Oncol. 2016 Apr;33(3):157-67. doi: 10.3109/08880018.2016.1161685.
503 A tool compound targeting the core binding factor Runt domain to disrupt binding to CBF in leukemic cells.Leuk Lymphoma. 2018 Sep;59(9):2188-2200. doi: 10.1080/10428194.2017.1410882. Epub 2017 Dec 18.
504 Knock-down of CIAPIN1 sensitizes K562 chronic myeloid leukemia cells to Imatinib by regulation of cell cycle and apoptosis-associated members via NF-B and ERK5 signaling pathway.Biochem Pharmacol. 2016 Jan 1;99:132-45. doi: 10.1016/j.bcp.2015.12.002. Epub 2015 Dec 8.
505 The concept of the okadaic acid class of tumor promoters is revived in endogenous protein inhibitors of protein phosphatase 2A, SET and CIP2A, in human cancers.J Cancer Res Clin Oncol. 2018 Dec;144(12):2339-2349. doi: 10.1007/s00432-018-2765-7. Epub 2018 Oct 20.
506 IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia.Transl Oncol. 2019 May;12(5):726-732. doi: 10.1016/j.tranon.2019.02.002. Epub 2019 Mar 13.
507 CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cell.BMC Cancer. 2019 May 27;19(1):499. doi: 10.1186/s12885-019-5671-8.
508 CD244 maintains the proliferation ability of leukemia initiating cells through SHP-2/p27(kip1) signaling.Haematologica. 2017 Apr;102(4):707-718. doi: 10.3324/haematol.2016.151555. Epub 2017 Jan 25.
509 Germline factor DDX4 functions in blood-derived cancer cell phenotypes.Cancer Sci. 2017 Aug;108(8):1612-1619. doi: 10.1111/cas.13299. Epub 2017 Jul 11.
510 Novel DDX41 variants in Thai patients with myeloid neoplasms.Int J Hematol. 2020 Feb;111(2):241-246. doi: 10.1007/s12185-019-02770-3. Epub 2019 Nov 11.
511 Protein phosphatase 1 (PP1) and Casein Kinase II (CK2) regulate Ikaros-mediated repression of TdT in thymocytes and T-cell leukemia.Pediatr Blood Cancer. 2014 Dec;61(12):2230-5. doi: 10.1002/pbc.25221. Epub 2014 Sep 11.
512 AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.Mol Cell. 2010 Feb 12;37(3):429-37. doi: 10.1016/j.molcel.2010.01.026.
513 An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation.Cancer Res. 2019 Aug 1;79(15):3862-3876. doi: 10.1158/0008-5472.CAN-18-3215. Epub 2019 Jun 7.
514 Downregulation of ENDOCAN in myeloid leukemia cells inhibits proliferation and promotes apoptosis by suppressing nuclear factorB activity.Mol Med Rep. 2019 Apr;19(4):3247-3254. doi: 10.3892/mmr.2019.9969. Epub 2019 Feb 19.
515 Graft-versus-leukemia target antigens in chronic myelogenous leukemia are expressed on myeloid progenitor cells.Clin Cancer Res. 2005 Jun 15;11(12):4504-11. doi: 10.1158/1078-0432.CCR-05-0036.
516 FAM168A participates in the development of chronic myeloid leukemia via BCR-ABL1/AKT1/NFB pathway.BMC Cancer. 2019 Jul 10;19(1):679. doi: 10.1186/s12885-019-5898-4.
517 Synergistic Effects of PI3K and c-Myc Co-targeting in Acute Leukemia: Shedding New Light on Resistance to Selective PI3K- Inhibitor CAL-101.Cancer Invest. 2019;37(7):311-324. doi: 10.1080/07357907.2019.1651328. Epub 2019 Aug 14.
518 FIP1L1 presence in FIP1L1-RARA or FIP1L1-PDGFRA differentially contributes to the pathogenesis of distinct types of leukemia.Ann Hematol. 2014 Sep;93(9):1473-81. doi: 10.1007/s00277-014-2085-1. Epub 2014 Apr 25.
519 CRIF1 interacting with CDK2 regulates bone marrow microenvironment-induced G0/G1 arrest of leukemia cells.PLoS One. 2014 Feb 10;9(2):e85328. doi: 10.1371/journal.pone.0085328. eCollection 2014.
520 MicroRNA in leukemia: Tumor suppressors and oncogenes with prognostic potential.J Cell Physiol. 2019 Jun;234(6):8465-8486. doi: 10.1002/jcp.27776. Epub 2018 Dec 4.
521 GINS2 regulates matrix metallopeptidase 9 expression and cancer stem cell property in human triple negative Breast cancer.Biomed Pharmacother. 2016 Dec;84:1568-1574. doi: 10.1016/j.biopha.2016.10.032. Epub 2016 Nov 6.
522 Molecular pathogenesis of disease progression in MLL-rearranged AML.Leukemia. 2019 Mar;33(3):612-624. doi: 10.1038/s41375-018-0253-3. Epub 2018 Sep 12.
523 The Marine Natural Product Pseudopterosin Blocks Cytokine Release of Triple-Negative Breast Cancer and Monocytic Leukemia Cells by Inhibiting NF-B Signaling.Mar Drugs. 2017 Aug 23;15(9):262. doi: 10.3390/md15090262.
524 Oncogenic heterogeneous nuclear ribonucleoprotein D-like modulates the growth and imatinib response of human chronic myeloid leukemia CD34(+) cells via pre-B-cell leukemia homeobox 1.Oncogene. 2020 Jan;39(2):443-453. doi: 10.1038/s41388-019-0998-9. Epub 2019 Sep 5.
525 Association of ARID5B and IKZF1 Variants with Leukemia from Northern India.Genet Test Mol Biomarkers. 2019 Mar;23(3):176-179. doi: 10.1089/gtmb.2018.0283. Epub 2019 Feb 27.
526 Dioncophyllines C(2), D(2), and F and Related Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ileboensis with Potent Activities against Plasmodium falciparum and against Multiple Myeloma and Leukemia Cell Lines.J Nat Prod. 2017 Feb 24;80(2):443-458. doi: 10.1021/acs.jnatprod.6b00967. Epub 2017 Jan 25.
527 The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML.Leukemia. 2019 Nov;33(11):2628-2639. doi: 10.1038/s41375-019-0581-y. Epub 2019 Oct 1.
528 MBD3/NuRD loss participates with KDM6A program to promote DOCK5/8 expression and Rac GTPase activation in human acute myeloid leukemia.FASEB J. 2019 Apr;33(4):5268-5286. doi: 10.1096/fj.201801035R. Epub 2019 Jan 22.
529 The Histone H3 Lysine 4 Presenter WDR5 as an Oncogenic Protein and Novel Epigenetic Target in Cancer.Front Oncol. 2018 Nov 14;8:502. doi: 10.3389/fonc.2018.00502. eCollection 2018.
530 Activation of the Lysosome-Associated Membrane Protein LAMP5 by DOT1L Serves as a Bodyguard for MLL Fusion Oncoproteins to Evade Degradation in Leukemia.Clin Cancer Res. 2019 May 1;25(9):2795-2808. doi: 10.1158/1078-0432.CCR-18-1474. Epub 2019 Jan 16.
531 Direct Reprogramming of Fibroblasts Into Smooth Muscle-Like Cells With Defined Transcription Factors-Brief Report.Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2191-2197. doi: 10.1161/ATVBAHA.118.310870.
532 Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.Exp Hematol. 2019 Jan;69:37-42. doi: 10.1016/j.exphem.2018.10.001. Epub 2018 Oct 10.
533 The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development.Blood Adv. 2019 Aug 13;3(15):2388-2399. doi: 10.1182/bloodadvances.2019000554.
534 Regulation and specificity of MNDA expression in monocytes, macrophages, and leukemia/B lymphoma cell lines.J Cell Biochem. 1994 Dec;56(4):559-67. doi: 10.1002/jcb.240560417.
535 Regulation of DNA methylation and tumor suppression gene expression by miR-29b in leukemia patients and related mechanisms.Eur Rev Med Pharmacol Sci. 2018 Jan;22(1):158-165. doi: 10.26355/eurrev_201801_14113.
536 Knockdown of immature colon carcinoma transcript1 induces suppression of proliferation, S-phase arrest and apoptosis in leukemia cells.Oncol Rep. 2018 Mar;39(3):1269-1275. doi: 10.3892/or.2018.6185. Epub 2018 Jan 3.
537 Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia.BMC Cancer. 2013 Oct 5;13:457. doi: 10.1186/1471-2407-13-457.
538 Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.Int J Hematol. 2014 Jan;99(1):21-31. doi: 10.1007/s12185-013-1466-x. Epub 2013 Nov 21.
539 Hypermethylation of the imprinted NNAT locus occurs frequently in pediatric acute leukemia.Carcinogenesis. 2002 Apr;23(4):559-64. doi: 10.1093/carcin/23.4.559.
540 NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.Mol Cell. 2015 Dec 17;60(6):847-59. doi: 10.1016/j.molcel.2015.10.033. Epub 2015 Nov 25.
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542 Knockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway.Cancer Manag Res. 2018 Oct 8;10:4311-4323. doi: 10.2147/CMAR.S173496. eCollection 2018.
543 Cryptic recurrent ACIN1-NUTM1 fusions in non-KMT2A-rearranged infant acute lymphoblastic leukemia.Genes Chromosomes Cancer. 2020 Feb;59(2):125-130. doi: 10.1002/gcc.22808. Epub 2019 Oct 4.
544 Assay of OAZ1 mRNA levels in chronic myeloid leukemia combined with application of leukemia PCR array identified relevant gene changes affected by antizyme.Acta Haematol. 2014;131(3):141-7. doi: 10.1159/000353406. Epub 2013 Oct 26.
545 HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML.Leukemia. 2013 Jun;27(6):1358-68. doi: 10.1038/leu.2012.366. Epub 2012 Dec 18.
546 Emerging Roles of MTG16 in Cell-Fate Control of Hematopoietic Stem Cells and Cancer.Stem Cells Int. 2017;2017:6301385. doi: 10.1155/2017/6301385. Epub 2017 Nov 22.
547 Synergistic antitumoral efficacy of a novel replicative adenovirus SG611-PDCD5 and daunorubicin in human leukemic cells.Onco Targets Ther. 2018 Aug 23;11:5121-5132. doi: 10.2147/OTT.S167868. eCollection 2018.
548 The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells.Leukemia. 2011 Apr;25(4):655-62. doi: 10.1038/leu.2010.301. Epub 2011 Jan 25.
549 Flow Cytometric Analysis of Mitochondrial Reactive Oxygen Species in Murine Hematopoietic Stem and Progenitor Cells and MLL-AF9 Driven Leukemia.J Vis Exp. 2019 Sep 5;(151):10.3791/59593. doi: 10.3791/59593.
550 A comparative study of molecular mutations in 381 patients with myelodysplastic syndrome and in 4130 patients with acute myeloid leukemia.Haematologica. 2007 Jun;92(6):744-52. doi: 10.3324/haematol.10869.
551 ETV6/ARG oncoprotein confers autonomous cell growth by enhancing c-Myc expression via signal transducer and activator of transcription 5 activation in the acute promyelocytic leukemia cell line HT93A.Leuk Lymphoma. 2015;56(8):2416-23. doi: 10.3109/10428194.2014.982643. Epub 2014 Dec 4.
552 FAS and RAS related Apoptosis defects: From autoimmunity to leukemia.Immunol Rev. 2019 Jan;287(1):50-61. doi: 10.1111/imr.12720.
553 Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome.Genes Dev. 2011 May 1;25(9):917-29. doi: 10.1101/gad.623011.
554 FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23).Leukemia. 2004 May;18(5):998-1005. doi: 10.1038/sj.leu.2403334.
555 Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed.Breast Cancer Res. 2012 Jan 9;14(1):101. doi: 10.1186/bcr3056.
556 Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5.mBio. 2019 Jun 11;10(3):e01071-19. doi: 10.1128/mBio.01071-19.
557 Structure characterization and anti-leukemia activity of a novel polysaccharide from Angelica sinensis (Oliv.) Diels.Int J Biol Macromol. 2019 Jan;121:161-172. doi: 10.1016/j.ijbiomac.2018.09.213. Epub 2018 Oct 2.
558 The inhibitory receptor toll interleukin-1R 8 (TIR8/IL-1R8/SIGIRR) is downregulated in chronic lymphocytic leukemia.Leuk Lymphoma. 2017 Oct;58(10):2419-2425. doi: 10.1080/10428194.2017.1295142. Epub 2017 Feb 28.
559 CD33 (Siglec-3) Inhibitory Function: Role in the NKG2D/DAP10 Activating Pathway.J Immunol Res. 2019 Apr 15;2019:6032141. doi: 10.1155/2019/6032141. eCollection 2019.
560 The roles of SNF2/SWI2 nucleosome remodeling enzymes in blood cell differentiation and leukemia.Biomed Res Int. 2015;2015:347571. doi: 10.1155/2015/347571. Epub 2015 Feb 19.
561 Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes.Oncogene. 2007 Jul 19;26(33):4797-805. doi: 10.1038/sj.onc.1210281. Epub 2007 Feb 19.
562 High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.Haematologica. 2020 Jan 31;105(2):435-447. doi: 10.3324/haematol.2019.216986. Print 2020.
563 Twins with different personalities: STAT5B-but not STAT5A-has a key role in BCR/ABL-induced leukemia.Leukemia. 2019 Jul;33(7):1583-1597. doi: 10.1038/s41375-018-0369-5. Epub 2019 Jan 24.
564 Mixed Phenotype Acute Leukemia with t(12;17)(p13;q21)/TAF15-ZNF384 and Other Chromosome Abnormalities.Cytogenet Genome Res. 2016;149(3):165-170. doi: 10.1159/000448447. Epub 2016 Sep 9.
565 MicroRNA-124 represses wound healing by targeting SERP1 and inhibiting the Wnt/-catenin pathway.Adv Clin Exp Med. 2019 Jun;28(6):711-718. doi: 10.17219/acem/94163.
566 Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix-Loop-Helix Peptides with Cell Penetrating and Tumor Suppressor Properties.ACS Chem Biol. 2019 Sep 20;14(9):2071-2087. doi: 10.1021/acschembio.9b00593. Epub 2019 Aug 21.
567 STIP Regulates ERK1/2 Signaling Pathway Involved in Interaction with PP1 in Lymphoblastic Leukemia.Curr Mol Med. 2016;16(8):767-775. doi: 10.2174/1566524016666161018154401.
568 PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia.Blood. 2019 Apr 18;133(16):1729-1741. doi: 10.1182/blood-2018-07-860726. Epub 2019 Feb 12.
569 Interferon-Inducible MicroRNA miR-128 Modulates HIV-1 Replication by Targeting TNPO3 mRNA.J Virol. 2019 Sep 30;93(20):e00364-19. doi: 10.1128/JVI.00364-19. Print 2019 Oct 15.
570 TNR/11q#1 trinucleotide (GCC)n repeat alleles and predisposition to acute and chronic leukemia.Ann Hum Genet. 2004 Jul;68(Pt 4):362-6. doi: 10.1046/j.1529-8817.2004.00101.x.
571 Attenuated expression of apoptosis stimulating protein of p53-2 (ASPP2) in human acute leukemia is associated with therapy failure.PLoS One. 2013 Nov 27;8(11):e80193. doi: 10.1371/journal.pone.0080193. eCollection 2013.
572 Expression of tumor protein D52-like genes in childhood leukemia at diagnosis: clinical and sample considerations.Leuk Res. 2006 Nov;30(11):1355-63. doi: 10.1016/j.leukres.2006.03.009. Epub 2006 Apr 18.
573 Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-B and -catenin/TCF signaling pathways.Cell Death Dis. 2018 Apr 1;9(4):427. doi: 10.1038/s41419-018-0440-1.
574 Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice.Leukemia. 2020 Mar;34(3):759-770. doi: 10.1038/s41375-019-0605-7. Epub 2019 Oct 17.
575 Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia.J Hematol Oncol. 2017 Jul 11;10(1):138. doi: 10.1186/s13045-017-0507-y.
576 Role of peroxisome proliferator-activated receptor-gamma and its coactivator DRIP205 in cellular responses to CDDO (RTA-401) in acute myelogenous leukemia.Cancer Res. 2010 Jun 15;70(12):4949-60. doi: 10.1158/0008-5472.CAN-09-1962. Epub 2010 May 25.
577 Analysis of CD137 and CD137L expression in human primary tumor tissues.Croat Med J. 2008 Apr;49(2):192-200. doi: 10.3325/cmj.2008.2.192.
578 A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cells.BMC Cancer. 2015 Sep 7;15:621. doi: 10.1186/s12885-015-1639-5.
579 ADCY7 supports development of acute myeloid leukemia.Biochem Biophys Res Commun. 2015 Sep 11;465(1):47-52. doi: 10.1016/j.bbrc.2015.07.123. Epub 2015 Jul 26.
580 The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output.Mol Cell Biol. 2012 Jul;32(13):2608-17. doi: 10.1128/MCB.00182-12. Epub 2012 Apr 30.
581 Sulforaphane Modulates AQP8-Linked Redox Signalling in Leukemia Cells.Oxid Med Cell Longev. 2018 Nov 18;2018:4125297. doi: 10.1155/2018/4125297. eCollection 2018.
582 METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m(6)A Modification.Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9. doi: 10.1016/j.stem.2017.11.016. Epub 2017 Dec 28.
583 ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.Cancer Discov. 2016 Jul;6(7):770-83. doi: 10.1158/2159-8290.CD-16-0058. Epub 2016 May 6.
584 ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.Nat Commun. 2017 May 18;8:15429. doi: 10.1038/ncomms15429.
585 Combined gene expression and DNA occupancy profiling identifies potential therapeutic targets of t(8;21) AML.Blood. 2012 Aug 16;120(7):1473-84. doi: 10.1182/blood-2011-12-395335. Epub 2012 Jun 26.
586 Dasatinib-induced anti-leukemia cellular immunity through a novel subset of CD57 positive helper/cytotoxic CD4 T cells in chronic myelogenous leukemia patients.Int J Hematol. 2018 Dec;108(6):588-597. doi: 10.1007/s12185-018-2517-0. Epub 2018 Aug 27.
587 A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.Oncogene. 2019 May;38(20):3824-3842. doi: 10.1038/s41388-018-0666-5. Epub 2019 Jan 22.
588 Vitamin K2 and cotylenin A synergistically induce monocytic differentiation and growth arrest along with the suppression of c-MYC expression and induction of cyclin G2 expression in human leukemia HL-60 cells.Int J Oncol. 2015 Aug;47(2):473-80. doi: 10.3892/ijo.2015.3028. Epub 2015 Jun 4.
589 Clinical and preclinical characterization of CD99 isoforms in acute myeloid leukemia.Haematologica. 2020 Apr;105(4):999-1012. doi: 10.3324/haematol.2018.207001. Epub 2019 Aug 1.
590 The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia.Oncogene. 2018 Jan 25;37(4):450-460. doi: 10.1038/onc.2017.337. Epub 2017 Sep 25.
591 CEMP1 Induces Transformation in Human Gingival Fibroblasts.PLoS One. 2015 May 26;10(5):e0127286. doi: 10.1371/journal.pone.0127286. eCollection 2015.
592 D40/KNL1/CASC5 and autosomal recessive primary microcephaly.Congenit Anom (Kyoto). 2017 Nov;57(6):191-196. doi: 10.1111/cga.12252. Epub 2017 Nov 1.
593 DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection.mBio. 2018 Jun 5;9(3):e00923-18. doi: 10.1128/mBio.00923-18.
594 Five-aza-2'-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells.Sci Rep. 2015 Nov 18;5:16709. doi: 10.1038/srep16709.
595 Hypoxia inhibits JAK2V617F activation via suppression of SHP-2 function in myeloproliferative neoplasm cells.Exp Hematol. 2014 Sep;42(9):783-92.e1. doi: 10.1016/j.exphem.2014.05.007. Epub 2014 May 23.
596 Isolation and Characterization of a Phaseolus vulgaris Trypsin Inhibitor with Antiproliferative Activity on Leukemia and Lymphoma Cells.Molecules. 2017 Jan 23;22(1):187. doi: 10.3390/molecules22010187.
597 DACT1 overexpression inhibits proliferation, enhances apoptosis, and increases daunorubicin chemosensitivity in KG-1 cells.Tumour Biol. 2017 Oct;39(10):1010428317711089. doi: 10.1177/1010428317711089.
598 Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical.Blood. 2007 Oct 1;110(7):2569-77. doi: 10.1182/blood-2006-12-062927. Epub 2007 Apr 17.
599 Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models.Metallomics. 2017 Mar 22;9(3):309-322. doi: 10.1039/c6mt00226a.
600 Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor.J Med Chem. 2018 Jul 26;61(14):6110-6120. doi: 10.1021/acs.jmedchem.8b00483. Epub 2018 Jul 17.
601 Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy.J Clin Invest. 2018 Dec 3;128(12):5383-5398. doi: 10.1172/JCI121366. Epub 2018 Oct 29.
602 Methylation-associated DOK1 and DOK2 down-regulation: Potential biomarkers for predicting adverse prognosis in acute myeloid leukemia.J Cell Physiol. 2018 Sep;233(9):6604-6614. doi: 10.1002/jcp.26271. Epub 2018 Mar 14.
603 Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth.Exp Cell Res. 2019 Sep 15;382(2):111485. doi: 10.1016/j.yexcr.2019.06.030. Epub 2019 Jun 26.
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606 Polymorphisms in XPC, XPD and XPG DNA repair genes and leukemia risk in a Tunisian population.Leuk Lymphoma. 2015 Jun;56(6):1856-62. doi: 10.3109/10428194.2014.974045. Epub 2014 Nov 14.
607 Disparate effects of Shb gene deficiency on disease characteristics in murine models of myeloid, B-cell, and T-cell leukemia.Tumour Biol. 2018 Apr;40(4):1010428318771472. doi: 10.1177/1010428318771472.
608 The Role of Regulatory B Cells in Patients with Acute Myeloid Leukemia.Med Sci Monit. 2019 Apr 24;25:3026-3031. doi: 10.12659/MSM.915556.
609 Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.J Exp Med. 2017 Mar 6;214(3):719-735. doi: 10.1084/jem.20161087. Epub 2017 Feb 15.
610 An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia.Oncogene. 2017 Oct 26;36(43):5985-5994. doi: 10.1038/onc.2017.210. Epub 2017 Jun 26.
611 The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.PLoS One. 2015 Jul 6;10(7):e0131716. doi: 10.1371/journal.pone.0131716. eCollection 2015.
612 Grb10 is involved in BCR-ABL-positive leukemia in mice.Leukemia. 2015 Apr;29(4):858-68. doi: 10.1038/leu.2014.283. Epub 2014 Sep 24.
613 Downregulation of miR?35a predicts poor prognosis in acute myeloid leukemia and regulates leukemia progression via modulating HOXA10 expression.Mol Med Rep. 2018 Jul;18(1):1134-1140. doi: 10.3892/mmr.2018.9066. Epub 2018 May 23.
614 Diptoindonesin G promotes ERK-mediated nuclear translocation of p-STAT1 (Ser727) and cell differentiation in AML cells.Cell Death Dis. 2017 May 4;8(5):e2765. doi: 10.1038/cddis.2017.159.
615 INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia.J Exp Clin Cancer Res. 2018 Jan 17;37(1):8. doi: 10.1186/s13046-018-0675-9.
616 JAM-C Identifies Src Family Kinase-Activated Leukemia-Initiating Cells and Predicts Poor Prognosis in Acute Myeloid Leukemia.Cancer Res. 2017 Dec 1;77(23):6627-6640. doi: 10.1158/0008-5472.CAN-17-1223. Epub 2017 Sep 28.
617 Generation and preclinical characterization of an NKp80-Fc fusion protein for redirected cytolysis of natural killer (NK) cells against leukemia.J Biol Chem. 2015 Sep 11;290(37):22474-84. doi: 10.1074/jbc.M115.678912. Epub 2015 Jul 21.
618 Quantitative detection of the human cervical cancer oncogene for monitoring the minimal residual disease in acute leukemia.Exp Biol Med (Maywood). 2015 Jan;240(1):128-34. doi: 10.1177/1535370214543067. Epub 2014 Jul 17.
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620 Chemoinformatic Approach to Assess Toxicity of Ionic Liquids.Methods Mol Biol. 2018;1800:559-571. doi: 10.1007/978-1-4939-7899-1_26.
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622 Activation of Wnt signaling pathway by AF1q enriches stem-like population and enhance mammosphere formation of breast cells.Biochem Biophys Res Commun. 2017 Mar 18;484(4):884-889. doi: 10.1016/j.bbrc.2017.02.018. Epub 2017 Feb 8.
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624 Clinical significance of high c-MYC and low MYCBP2 expression and their association with Ikaros dysfunction in adult acute lymphoblastic leukemia.Oncotarget. 2015 Dec 8;6(39):42300-11. doi: 10.18632/oncotarget.5982.
625 Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer.J Cell Biochem. 2015 Oct;116(10):2146-54. doi: 10.1002/jcb.25203.
626 Necdin modulates leukemia-initiating cell quiescence and chemotherapy response.Oncotarget. 2017 Sep 18;8(50):87607-87622. doi: 10.18632/oncotarget.20999. eCollection 2017 Oct 20.
627 DNAM-1-based chimeric antigen receptors enhance T cell effector function and exhibit in vivo efficacy against melanoma.Cancer Immunol Immunother. 2015 Apr;64(4):409-18. doi: 10.1007/s00262-014-1648-2. Epub 2014 Dec 31.
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728 Bufalin Enhances Immune Responses in Leukemic Mice Through Enhancing Phagocytosis of Macrophage In Vivo.In Vivo. 2018 Sep-Oct;32(5):1129-1136. doi: 10.21873/invivo.11355.
729 The Association of Flap Endonuclease 1 Genotypes with the Risk of Childhood Leukemia.Cancer Genomics Proteomics. 2016 Jan-Feb;13(1):69-74.
730 LncRNA expression profile of Np63 in cervical squamous cancers and its suppressive effects on LIF expression.Cytokine. 2017 Aug;96:114-122. doi: 10.1016/j.cyto.2017.04.001. Epub 2017 Apr 7.
731 Myeloid leukemia development in c-Cbl RING finger mutant mice is dependent on FLT3 signaling.Cancer Cell. 2010 Oct 19;18(4):341-52. doi: 10.1016/j.ccr.2010.09.008.
732 The transcriptional regulator FUBP1 influences disease outcome in murine and human myeloid leukemia.Leukemia. 2019 Jul;33(7):1700-1712. doi: 10.1038/s41375-018-0358-8. Epub 2019 Jan 11.
733 Genotoxicity of retroviral hematopoietic stem cell gene therapy.Expert Opin Biol Ther. 2011 May;11(5):581-93. doi: 10.1517/14712598.2011.562496. Epub 2011 Mar 7.
734 Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia.Mol Med Rep. 2016 Aug;14(2):1339-44. doi: 10.3892/mmr.2016.5387. Epub 2016 Jun 10.
735 Inhibition of the Gab2/PI3K/mTOR signaling ameliorates myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations.Leukemia. 2017 Jun;31(6):1415-1422. doi: 10.1038/leu.2016.326. Epub 2016 Nov 14.
736 Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia.Oncotarget. 2017 Feb 14;8(7):10809-10821. doi: 10.18632/oncotarget.14580.
737 Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors.Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2814-9. doi: 10.1073/pnas.050397097.
738 Whole-exome sequencing of a rare case of familial childhood acute lymphoblastic leukemia reveals putative predisposing mutations in Fanconi anemia genes.BMC Cancer. 2015 Jul 23;15:539. doi: 10.1186/s12885-015-1549-6.
739 Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice.Leukemia. 2019 Jan;33(1):110-121. doi: 10.1038/s41375-018-0166-1. Epub 2018 Jun 20.
740 A somatic mutation of GFI1B identified in leukemia alters cell fate via a SPI1 (PU.1) centered genetic regulatory network.Dev Biol. 2016 Mar 15;411(2):277-286. doi: 10.1016/j.ydbio.2016.02.002. Epub 2016 Feb 3.
741 Expression of human GIPC1 in normal tissues, cancer cell lines, and primary tumors.Int J Mol Med. 2002 May;9(5):509-13.
742 hIL-15-gene modified human natural killer cells (NKL-IL15) exhibit anti-human leukemia functions.J Cancer Res Clin Oncol. 2018 Jul;144(7):1279-1288. doi: 10.1007/s00432-018-2654-0. Epub 2018 May 8.
743 Nucleostemin silencing induces differentiation and potentiates all-trans-retinoic acid effects in human acute promyelocytic leukemia NB4 cells via autophagy.Leuk Res. 2017 Dec;63:15-21. doi: 10.1016/j.leukres.2017.10.007. Epub 2017 Oct 26.
744 The small oligomerization domain of gephyrin converts MLL to an oncogene.Blood. 2004 May 15;103(10):3876-82. doi: 10.1182/blood-2003-11-3817. Epub 2004 Jan 29.
745 ITR?84 modulates cell differentiation in human chronic myelogenous leukemia K562 cells.Oncol Rep. 2018 Jan;39(1):383-391. doi: 10.3892/or.2017.6090. Epub 2017 Nov 9.
746 Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers.Cancer Res. 2004 Apr 1;64(7):2411-7. doi: 10.1158/0008-5472.can-03-0164.
747 Somatic mutations at T-cell antigen receptor and glycophorin A loci in pediatric leukemia patients following chemotherapy: comparison with HPRT locus mutation.Mutat Res. 1994 Sep;315(2):95-103. doi: 10.1016/0921-8777(94)90010-8.
748 Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors.Mol Cancer Ther. 2018 Aug;17(8):1694-1704. doi: 10.1158/1535-7163.MCT-18-0028. Epub 2018 May 10.
749 Anti-leukemic effects of HDACi Belinostat and HMTi 3-Deazaneplanocin A on human acute promyelocytic leukemia cells.Eur J Pharmacol. 2017 Mar 15;799:143-153. doi: 10.1016/j.ejphar.2017.02.014. Epub 2017 Feb 10.
750 Impact of hemochromatosis gene mutations on cardiac status in doxorubicin-treated survivors of childhood high-risk leukemia.Cancer. 2013 Oct 1;119(19):3555-62. doi: 10.1002/cncr.28256. Epub 2013 Jul 16.
751 Prognostic significance of huntingtin interacting protein 1 expression on patients with acute myeloid leukemia.Sci Rep. 2017 Apr 28;7:45960. doi: 10.1038/srep45960.
752 Patients Lacking a KIR-Ligand of HLA Group C1 or C2 Have a Better Outcome after Umbilical Cord Blood Transplantation.Front Immunol. 2017 Jul 13;8:810. doi: 10.3389/fimmu.2017.00810. eCollection 2017.
753 Identification of the new HLA-DPB1 allele, DPB1*647:01, in an Italian patient with leukemia.HLA. 2018 Apr;91(4):311-312. doi: 10.1111/tan.13235. Epub 2018 Feb 26.
754 The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability.Cancer Cell. 2019 Dec 9;36(6):630-644.e9. doi: 10.1016/j.ccell.2019.10.004. Epub 2019 Nov 14.
755 TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.Blood. 2012 Apr 12;119(15):3440-9. doi: 10.1182/blood-2011-06-357939. Epub 2012 Feb 27.
756 The homeodomain region controls the phenotype of HOX-induced murine leukemia.Blood. 2012 Nov 8;120(19):4018-27. doi: 10.1182/blood-2011-10-384685. Epub 2012 Sep 18.
757 Expression of selected human HOX-2 genes in B/T acute lymphoid leukemia and interleukin-2/interleukin-1 beta-stimulated natural killer lymphocytes.Blood. 1992 Jul 1;80(1):185-93.
758 Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivo.Blood. 2014 Sep 11;124(11):1737-47. doi: 10.1182/blood-2013-10-534735. Epub 2014 Jul 31.
759 HOXC10 is overexpressed in breast cancer and transcriptionally regulated by estrogen via involvement of histone methylases MLL3 and MLL4.J Mol Endocrinol. 2012 Jan 25;48(1):61-75. doi: 10.1530/JME-11-0078. Print 2012 Feb.
760 Heterogenous fusion transcripts involving the NUP98 gene and HOXD13 gene activation in a case of acute myeloid leukemia with the t(2;11)(q31;p15) translocation.Leukemia. 2000 Sep;14(9):1621-9. doi: 10.1038/sj.leu.2401881.
761 Identification of an overexpressed gene, HSPA4L, the product of which can provoke prevalent humoral immune responses in leukemia patients.Exp Hematol. 2007 Jul;35(7):1091-9. doi: 10.1016/j.exphem.2007.03.015.
762 Molecular cloning of six novel Krppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB.J Biol Chem. 1999 Dec 10;274(50):35741-8. doi: 10.1074/jbc.274.50.35741.
763 Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes.Cancer Res. 2009 Oct 1;69(19):7518-23. doi: 10.1158/0008-5472.CAN-09-1428. Epub 2009 Sep 22.
764 RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1.Leukemia. 2020 May;34(5):1354-1363. doi: 10.1038/s41375-019-0656-9. Epub 2019 Nov 25.
765 Identification of characteristic IGF2BP expression patterns in distinct B-ALL entities.Blood Cells Mol Dis. 2011 Apr 15;46(4):321-6. doi: 10.1016/j.bcmd.2011.02.005. Epub 2011 Mar 17.
766 Insulin-like growth factor-binding protein 4 in children with acute lymphoblastic leukemia.Int J Hematol. 2005 Aug;82(2):137-42. doi: 10.1532/IJH97.E0429.
767 CD8?innate-type lymphocytes in the intestinal epithelium mediate mucosal immunity.Immunity. 2014 Sep 18;41(3):451-464. doi: 10.1016/j.immuni.2014.08.010. Epub 2014 Sep 11.
768 IL-3 and GM-CSF modulate functions of splenic macrophages in ENU induced leukemia.Cytokine. 2017 Mar;91:89-95. doi: 10.1016/j.cyto.2016.12.009. Epub 2016 Dec 28.
769 Gene expression profiling identifies IRF4-associated molecular signatures in hematological malignancies.PLoS One. 2014 Sep 10;9(9):e106788. doi: 10.1371/journal.pone.0106788. eCollection 2014.
770 JARID2 inhibits leukemia cell proliferation by regulating CCND1 expression.Int J Hematol. 2015 Jul;102(1):76-85. doi: 10.1007/s12185-015-1797-x. Epub 2015 May 5.
771 Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.Cancer Res. 2017 Apr 1;77(7):1753-1762. doi: 10.1158/0008-5472.CAN-16-2374. Epub 2017 Feb 15.
772 Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.Leuk Res. 2010 Jan;34(1):55-8. doi: 10.1016/j.leukres.2009.04.022. Epub 2009 May 18.
773 KIR2DS5 is associated with leukemia free survival after HLA identical stem cell transplantation in chronic myeloid leukemia patients.Mol Immunol. 2008 Aug;45(13):3631-8. doi: 10.1016/j.molimm.2008.04.016. Epub 2008 Jun 16.
774 Survey and evaluation of mutations in the human KLF1 transcription unit.Sci Rep. 2018 Apr 26;8(1):6587. doi: 10.1038/s41598-018-24962-3.
775 High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations.Blood. 2012 Mar 8;119(10):e67-75. doi: 10.1182/blood-2011-09-380444. Epub 2012 Jan 10.
776 Hypoxia selects for a quiescent, CML stem/leukemia initiating-like population dependent on CBP/catenin transcription.Curr Mol Pharmacol. 2013 Nov;6(3):204-10. doi: 10.2174/1874467207666140219121219.
777 The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).J Biol Chem. 2003 Apr 25;278(17):15412-20. doi: 10.1074/jbc.M300592200. Epub 2003 Feb 14.
778 LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.Mol Cell Biol. 2015 Nov 23;36(3):488-506. doi: 10.1128/MCB.00901-15. Print 2016 Feb 1.
779 Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines.Biochim Biophys Acta. 2014;1839(4):265-74. doi: 10.1016/j.bbagrm.2014.02.004. Epub 2014 Feb 13.
780 Pinch-1 was up-regulated in leukemia BMSC and its possible effect.Clin Exp Med. 2013 Feb;13(1):21-7. doi: 10.1007/s10238-012-0176-7. Epub 2012 Feb 5.
781 The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML.J Exp Med. 2013 Jan 14;210(1):15-22. doi: 10.1084/jem.20120596. Epub 2012 Dec 31.
782 ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9.Genes Chromosomes Cancer. 2016 Mar;55(3):242-50. doi: 10.1002/gcc.22327. Epub 2015 Nov 6.
783 The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.Haematologica. 2012 Sep;97(9):1405-13. doi: 10.3324/haematol.2011.059030. Epub 2012 Apr 4.
784 Latexin is down-regulated in hematopoietic malignancies and restoration of expression inhibits lymphoma growth.PLoS One. 2012;7(9):e44979. doi: 10.1371/journal.pone.0044979. Epub 2012 Sep 27.
785 MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily.Gene. 2001 Apr 18;267(2):173-82. doi: 10.1016/s0378-1119(01)00406-1.
786 MicroRNA 146a Polymorphisms and Expression in Indian Children with Acute Lymphoblastic Leukemia.Lab Med. 2019 Jul 16;50(3):249-253. doi: 10.1093/labmed/lmy074.
787 Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients.Blood. 1998 Jun 15;91(12):4480-8.
788 Role of N(6)-methyladenosine modification in cancer.Curr Opin Genet Dev. 2018 Feb;48:1-7. doi: 10.1016/j.gde.2017.10.005. Epub 2017 Oct 14.
789 Cancer-associated expression of minichromosome maintenance 3 gene in several human cancers and its involvement in tumorigenesis.Clin Cancer Res. 2004 Dec 15;10(24):8386-95. doi: 10.1158/1078-0432.CCR-04-1029.
790 Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2.PLoS One. 2010 Sep 2;5(9):e12520. doi: 10.1371/journal.pone.0012520.
791 Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.EBioMedicine. 2016 Jun;8:173-183. doi: 10.1016/j.ebiom.2016.04.038. Epub 2016 May 13.
792 Meis2 as a critical player in MN1-induced leukemia.Blood Cancer J. 2017 Sep 29;7(9):e613. doi: 10.1038/bcj.2017.86.
793 The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18.
794 Triptolide induces apoptosis in human leukemia cells through caspase-3-mediated ROCK1 activation and MLC phosphorylation.Cell Death Dis. 2013 Dec 5;4(12):e941. doi: 10.1038/cddis.2013.469.
795 NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes.PLoS Genet. 2019 Nov 1;15(11):e1008463. doi: 10.1371/journal.pgen.1008463. eCollection 2019 Nov.
796 De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia.Nat Commun. 2018 May 2;9(1):1770. doi: 10.1038/s41467-018-04180-1.
797 ChREBP promotes the differentiation of leukemia-initiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways.Oncotarget. 2016 Jun 21;7(25):38347-38358. doi: 10.18632/oncotarget.9520.
798 A MENage Trois in leukemia.Cancer Cell. 2008 Jul 8;14(1):3-5. doi: 10.1016/j.ccr.2008.06.009.
799 The dual role of HLXB9 in leukemia.Pediatr Blood Cancer. 2011 Mar;56(3):349-52. doi: 10.1002/pbc.22679.
800 Moloney leukemia virus 10 (MOV10) protein inhibits retrovirus replication.J Biol Chem. 2010 May 7;285(19):14346-55. doi: 10.1074/jbc.M110.109314. Epub 2010 Mar 9.
801 Ecotropic viral integration site 1 regulates the progression of acute myeloid leukemia via MS4A3-mediated TGF/EMT signaling pathway.Oncol Lett. 2018 Aug;16(2):2701-2708. doi: 10.3892/ol.2018.8890. Epub 2018 Jun 4.
802 Epigenetic analysis of childhood acute lymphoblastic leukemia.Epigenetics. 2009 Apr 1;4(3):185-93. doi: 10.4161/epi.4.3.8752. Epub 2009 Apr 12.
803 Predictive value of multidrug resistance proteins and cellular drug resistance in childhood relapsed acute lymphoblastic leukemia.J Cancer Res Clin Oncol. 2007 Nov;133(11):875-93. doi: 10.1007/s00432-007-0274-1. Epub 2007 Aug 2.
804 Tax oncoprotein trans-represses endogenous B-myb promoter activity in human T cells.AIDS Res Hum Retroviruses. 2000 Nov 1;16(16):1629-32. doi: 10.1089/08892220050193065.
805 Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells.Nucleic Acids Res. 2010 Sep;38(16):5384-95. doi: 10.1093/nar/gkq307. Epub 2010 Apr 28.
806 Attenuation of AML1-ETO cellular dysregulation correlates with increased leukemogenic potential.Blood. 2013 May 2;121(18):3714-7. doi: 10.1182/blood-2012-11-465641. Epub 2013 Feb 20.
807 The leukemia-associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A.Biochem Biophys Res Commun. 1999 Nov 2;264(3):871-7. doi: 10.1006/bbrc.1999.1605.
808 Deficient expression of NCR in NK cells from acute myeloid leukemia: Evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction.Blood. 2007 Jan 1;109(1):323-30. doi: 10.1182/blood-2005-08-027979. Epub 2006 Aug 29.
809 Chromosome band 16q22-linked familial AML: exclusion of candidate genes, and possible disease risk modification by NQO1 polymorphisms.Genes Chromosomes Cancer. 2004 Nov;41(3):278-82. doi: 10.1002/gcc.20084.
810 Functional polymorphisms in the NBS1 gene and acute lymphoblastic leukemia susceptibility in a Chinese population.Eur J Haematol. 2011 Mar;86(3):199-205. doi: 10.1111/j.1600-0609.2010.01562.x. Epub 2011 Jan 25.
811 Establishment of a myeloid leukemia cell line, TRL-01, with MLL-ENL fusion gene.Cancer Genet Cytogenet. 2006 Aug;169(1):1-11. doi: 10.1016/j.cancergencyto.2005.09.008.
812 Superoxide-Generating Nox5 Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype.J Virol. 2015 Sep;89(17):9080-9. doi: 10.1128/JVI.00983-15. Epub 2015 Jun 24.
813 NRARP displays either pro- or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling.Oncogene. 2020 Jan;39(5):975-986. doi: 10.1038/s41388-019-1042-9. Epub 2019 Oct 4.
814 A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia.JCI Insight. 2019 Dec 5;4(23):e131434. doi: 10.1172/jci.insight.131434.
815 The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia.Exp Hematol. 2017 Nov;55:76-85.e3. doi: 10.1016/j.exphem.2017.07.009. Epub 2017 Jul 28.
816 PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity. Hum Mol Genet. 2012 Nov 1;21(21):4793-804.
817 The functional polymorphisms of LIS1 are associated with acute myeloid leukemia risk in a Han Chinese population.Leuk Res. 2017 Mar;54:7-11. doi: 10.1016/j.leukres.2016.12.007. Epub 2017 Jan 2.
818 Fluctuation of gene expression for poly(ADP-ribose) synthetase during hemin-induced erythroid differentiation of human leukemia K562 cells and its reversion process.Biochim Biophys Acta. 1991 Mar 26;1088(3):359-64. doi: 10.1016/0167-4781(91)90125-6.
819 PBX3 is essential for leukemia stem cell maintenance in MLL-rearranged leukemia.Int J Cancer. 2017 Jul 15;141(2):324-335. doi: 10.1002/ijc.30739. Epub 2017 May 8.
820 Promoter methylation-mediated inactivation of PCDH10 in acute lymphoblastic leukemia contributes to chemotherapy resistance.Genes Chromosomes Cancer. 2011 Dec;50(12):1043-53. doi: 10.1002/gcc.20922. Epub 2011 Aug 24.
821 Protein signaling and regulation of gene transcription in leukemia: role of the Casein Kinase II-Ikaros axis.J Investig Med. 2016 Mar;64(3):735-9. doi: 10.1136/jim-2016-000075. Epub 2016 Feb 9.
822 The influence of intracellular idarubicin and daunorubicin levels on drug cytotoxicity in childhood acute leukemia.Acta Biochim Pol. 2002;49(1):99-107.
823 The prohibitin protein complex promotes mitochondrial stabilization and cell survival in hematologic malignancies.Oncotarget. 2017 Jul 1;8(39):65445-65456. doi: 10.18632/oncotarget.18920. eCollection 2017 Sep 12.
824 Lack of the Polycomb-group gene rae28 causes maturation arrest at the early B-cell developmental stage.Exp Hematol. 2001 Jan;29(1):93-103. doi: 10.1016/s0301-472x(00)00620-2.
825 Identification of phosphatidylinositol 4-kinase type II beta as HLA class II-restricted target in graft versus leukemia reactivity.Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3837-42. doi: 10.1073/pnas.0712250105. Epub 2008 Mar 3.
826 The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.Cancer Res. 2012 May 1;72(9):2275-84. doi: 10.1158/0008-5472.CAN-11-3159. Epub 2012 Mar 9.
827 Regulatory Network and Prognostic Effect Investigation of PIP4K2A in Leukemia and Solid Cancers.Front Genet. 2019 Jan 15;9:721. doi: 10.3389/fgene.2018.00721. eCollection 2018.
828 Protein kinase D2: a versatile player in cancer biology.Oncogene. 2018 Mar;37(10):1263-1278. doi: 10.1038/s41388-017-0052-8. Epub 2017 Dec 20.
829 The putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA.Apoptosis. 2014 Jan;19(1):201-9. doi: 10.1007/s10495-013-0910-y.
830 Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors.Mol Carcinog. 2001 Sep;32(1):44-53. doi: 10.1002/mc.1063.
831 Human CAP10-Like Protein 46kDa Gene Promotes Malignancy in Colorectal Cancer.OMICS. 2017 May;21(5):266-274. doi: 10.1089/omi.2017.0037.
832 POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature.Leukemia. 2010 May;24(5):950-7. doi: 10.1038/leu.2010.61. Epub 2010 Apr 8.
833 Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells.Proc Natl Acad Sci U S A. 1987 May;84(9):2868-71. doi: 10.1073/pnas.84.9.2868.
834 Expression and distribution of PPP2R5C gene in leukemia.J Hematol Oncol. 2011 May 6;4:21. doi: 10.1186/1756-8722-4-21.
835 DNA methylation in ATRA-treated leukemia cell lines lacking a PML-RAR chromosome translocation.Anticancer Res. 2012 Nov;32(11):4715-22.
836 The B-lymphocyte maturation promoting transcription factor BLIMP1/PRDI-BF1 maps to D6S447 on human chromosome 6q21-q22.1 and the syntenic region of mouse chromosome 10.Genomics. 1996 Oct 1;37(1):24-8. doi: 10.1006/geno.1996.0516.
837 The Pluripotency Regulator PRDM14 Requires Hematopoietic Regulator CBFA2T3 to Initiate Leukemia in Mice.Mol Cancer Res. 2019 Jul;17(7):1468-1479. doi: 10.1158/1541-7786.MCR-18-1327. Epub 2019 Apr 23.
838 Nucleotide alteration of retinoblastoma protein-interacting zinc finger gene, RIZ, in human leukemia.Tohoku J Exp Med. 2002 Mar;196(3):193-201. doi: 10.1620/tjem.196.193.
839 Leukemogenic properties of NUP98-PMX1 are linked to NUP98 and homeodomain sequence functions but not to binding properties of PMX1 to serum response factor.Oncogene. 2008 Oct 9;27(46):6056-67. doi: 10.1038/onc.2008.210. Epub 2008 Jul 7.
840 AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia.Blood. 2011 Dec 1;118(23):6132-40. doi: 10.1182/blood-2011-01-323147. Epub 2011 Oct 14.
841 GATA4 is highly expressed in childhood acute lymphoblastic leukemia, promotes cell proliferation and inhibits apoptosis by activating BCL2 and MDM2.Mol Med Rep. 2017 Nov;16(5):6290-6298. doi: 10.3892/mmr.2017.7369. Epub 2017 Aug 28.
842 From oncogene to tumor suppressor: the dual role of Myc in leukemia.Cell Cycle. 2012 May 1;11(9):1757-64. doi: 10.4161/cc.19883. Epub 2012 May 1.
843 Mechanisms involved in the induced differentiation of leukemia cells.Pharmacol Ther. 2003 Dec;100(3):257-90. doi: 10.1016/j.pharmthera.2003.09.002.
844 Vav1 increases Bcl-2 expression by selective activation of Rac2-Akt in leukemia T cells.Cell Signal. 2014 Oct;26(10):2202-9. doi: 10.1016/j.cellsig.2014.05.015. Epub 2014 May 29.
845 Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells.Cell Rep. 2018 Jun 12;23(11):3127-3136. doi: 10.1016/j.celrep.2018.05.034.
846 RAG1/2 induces genomic insertions by mobilizing DNA into RAG1/2-independent breaks.J Exp Med. 2017 Mar 6;214(3):815-831. doi: 10.1084/jem.20161638. Epub 2017 Feb 8.
847 Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphoma. PLoS One. 2013 Nov 6;8(11):e79863. doi: 10.1371/journal.pone.0079863. eCollection 2013.
848 Rap1GAP alters leukemia cell differentiation, apoptosis and invasion invitro.Oncol Rep. 2012 Aug;28(2):622-8. doi: 10.3892/or.2012.1825. Epub 2012 May 18.
849 The distinct role of guanine nucleotide exchange factor Vav1 in Bcl-2 transcription and apoptosis inhibition in Jurkat leukemia T cells.Acta Pharmacol Sin. 2011 Jan;32(1):99-107. doi: 10.1038/aps.2010.185. Epub 2010 Dec 13.
850 Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity.J Biol Chem. 2008 Sep 26;283(39):26820-8. doi: 10.1074/jbc.M802315200. Epub 2008 Jul 30.
851 Intestinal folate transport: identification of a cDNA involved in folate transport and the functional expression and distribution of its mRNA.Biochim Biophys Acta. 1996 Jun 11;1281(2):164-72. doi: 10.1016/0005-2736(96)00005-3.
852 Genomic c-Myc quadruplex DNA selectively kills leukemia.Mol Cancer Ther. 2012 Jan;11(1):66-76. doi: 10.1158/1535-7163.MCT-11-0515. Epub 2011 Nov 14.
853 Identification of RHOXF2 (PEPP2) as a cancer-promoting gene by expression cloning.Int J Oncol. 2012 Jan;40(1):93-8. doi: 10.3892/ijo.2011.1173. Epub 2011 Aug 19.
854 Mechanisms of acquired resistance to ERK1/2 pathway inhibitors.Oncogene. 2013 Mar 7;32(10):1207-15. doi: 10.1038/onc.2012.160. Epub 2012 May 7.
855 Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia.Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3901-6. doi: 10.1073/pnas.1301045110. Epub 2013 Feb 14.
856 Breakpoints at 1p36.3 in three MDS/AML(M4) patients with t(1;3)(p36;q21) occur in the first intron and in the 5' region of MEL1.Genes Chromosomes Cancer. 2003 Mar;36(3):313-6. doi: 10.1002/gcc.10176.
857 Changing pattern of secondary cancers among patients with malignant thymoma in the USA.Future Oncol. 2018 Aug;14(19):1943-1951. doi: 10.2217/fon-2017-0626. Epub 2018 Aug 7.
858 The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis.Leukemia. 2013 Jul;27(7):1461-8. doi: 10.1038/leu.2013.42. Epub 2013 Feb 13.
859 Persistent detection of a novel MLL-SACM1L rearrangement in the absence of leukemia.Leuk Res. 2010 Oct;34(10):1398-401. doi: 10.1016/j.leukres.2010.05.001.
860 The Study of SALL4 Gene and BMI-1 Gene Expression in Acute Myeloid Leukemia Patients.Lab Med. 2020 May 6;51(3):265-270. doi: 10.1093/labmed/lmz056.
861 Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML.Nat Commun. 2019 Aug 2;10(1):3475. doi: 10.1038/s41467-019-11413-4.
862 High frequency of BTG1 deletions in acute lymphoblastic leukemia in children with down syndrome.Genes Chromosomes Cancer. 2012 Feb;51(2):196-206. doi: 10.1002/gcc.20944. Epub 2011 Nov 10.
863 Blocking the proliferation of human tumor cell lines by peptidase inhibitors from Bauhinia seeds.Planta Med. 2013 Mar;79(3-4):227-35. doi: 10.1055/s-0032-1328156. Epub 2013 Jan 23.
864 Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.Mol Cell Biol. 2004 Jul;24(13):5639-49. doi: 10.1128/MCB.24.13.5639-5649.2004.
865 Novel mutations in ataxia telangiectasia and AOA2 associated with prolonged survival.J Neurol Sci. 2013 Dec 15;335(1-2):134-8. doi: 10.1016/j.jns.2013.09.014. Epub 2013 Sep 17.
866 Methylation of SFRP5 is related to multidrug resistance in leukemia cells.Cancer Gene Ther. 2014 Feb;21(2):83-9. doi: 10.1038/cgt.2013.87. Epub 2014 Jan 17.
867 PCR testing for HCV in anti-HCV negative blood donors involved in the so called HCV +ve post-transfusion hepatitis.Transfus Sci. 2000 Jun;22(3):161-4. doi: 10.1016/s0955-3886(00)00043-6.
868 Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO.Haematologica. 2008 Nov;93(11):1728-33. doi: 10.3324/haematol.13044. Epub 2008 Sep 11.
869 Differential expression of a novel C-terminally truncated splice form of SMAD5 in hematopoietic stem cells and leukemia.Blood. 2000 Jun 15;95(12):3945-50.
870 Epigenetic control of SPI1 gene by CTCF and ISWI ATPase SMARCA5.PLoS One. 2014 Feb 3;9(2):e87448. doi: 10.1371/journal.pone.0087448. eCollection 2014.
871 Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes. Nat Genet. 2017 May;49(5):742-752. doi: 10.1038/ng.3833. Epub 2017 Apr 3.
872 Structural maintenance of chromosomes 4 is required for leukemia stem cell maintenance in MLL-AF9 induced acute myeloid leukemia.Leuk Lymphoma. 2018 Oct;59(10):2423-2430. doi: 10.1080/10428194.2017.1387906. Epub 2017 Oct 18.
873 Epigenetic regulator Smchd1 functions as a tumor suppressor.Cancer Res. 2013 Mar 1;73(5):1591-9. doi: 10.1158/0008-5472.CAN-12-3019. Epub 2012 Dec 26.
874 PML a target of translocations in APL is a regulator of cellular senescence.Leukemia. 2002 Oct;16(10):1918-26. doi: 10.1038/sj.leu.2402722.
875 Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II.J Biol Chem. 1999 Jul 30;274(31):21981-5. doi: 10.1074/jbc.274.31.21981.
876 Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia.Cell Res. 2018 Feb;28(2):172-186. doi: 10.1038/cr.2017.146. Epub 2017 Nov 17.
877 Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia.Cancer Sci. 2019 Jun;110(6):1931-1946. doi: 10.1111/cas.14021. Epub 2019 May 3.
878 SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes.Mol Cell. 2016 Mar 17;61(6):859-73. doi: 10.1016/j.molcel.2016.02.024.
879 SOX6 blocks the proliferation of BCR-ABL1(+) and JAK2V617F(+) leukemic cells.Sci Rep. 2019 Mar 4;9(1):3388. doi: 10.1038/s41598-019-39926-4.
880 Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia.Blood. 2015 Jun 18;125(25):3928-36. doi: 10.1182/blood-2014-06-580993. Epub 2015 May 4.
881 The PML nuclear bodies: actors or extras?.Curr Opin Genet Dev. 1999 Jun;9(3):362-7. doi: 10.1016/s0959-437x(99)80054-9.
882 Identification of SPAG9 as a novel JAK2 fusion partner gene in pediatric acute lymphoblastic leukemia with t(9;17)(p24;q21).Genes Chromosomes Cancer. 2015 Jul;54(7):401-8. doi: 10.1002/gcc.22251. Epub 2015 May 7.
883 Combined high-resolution array-based comparative genomic hybridization and expression profiling of ETV6/RUNX1-positive acute lymphoblastic leukemias reveal a high incidence of cryptic Xq duplications and identify several putative target genes within the commonly gained region.Leukemia. 2007 Oct;21(10):2137-44. doi: 10.1038/sj.leu.2404879. Epub 2007 Aug 9.
884 The Spi1/PU.1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemia.Oncotarget. 2017 Jun 6;8(23):37104-37114. doi: 10.18632/oncotarget.16183.
885 ETV6-RUNX1 interacts with a region in SPIB intron 1 to regulate gene expression in pre-B-cell acute lymphoblastic leukemia.Exp Hematol. 2019 May;73:50-63.e2. doi: 10.1016/j.exphem.2019.03.004. Epub 2019 Apr 12.
886 Sorcin, an important gene associated with multidrug-resistance in human leukemia cells.Leuk Res. 2006 Apr;30(4):469-76. doi: 10.1016/j.leukres.2005.08.024. Epub 2005 Oct 6.
887 STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.Cell Rep. 2018 Sep 11;24(11):3045-3060.e5. doi: 10.1016/j.celrep.2018.08.030.
888 The Oncogenic Potential of SUV39H2: A Comprehensive and Perspective View.J Cancer. 2019 Jan 1;10(3):721-729. doi: 10.7150/jca.28254. eCollection 2019.
889 N-terminally truncated WT1 protein with oncogenic properties overexpressed in leukemia.J Biol Chem. 2006 Sep 22;281(38):28122-30. doi: 10.1074/jbc.M512391200. Epub 2006 May 12.
890 Splicing factor SF3B1K700E mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1.PLoS One. 2017 May 18;12(5):e0175523. doi: 10.1371/journal.pone.0175523. eCollection 2017.
891 Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia.Haematologica. 2016 Aug;101(8):951-8. doi: 10.3324/haematol.2016.143875. Epub 2016 May 5.
892 Expression of transcobalamin II receptors by human leukemia K562 and HL-60 cells.Blood. 1990 Oct 1;76(7):1380-6.
893 The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties.Blood. 1996 Jun 1;87(11):4607-17.
894 Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo.Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):806-13.
895 A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML.Blood. 2014 Apr 17;123(16):2530-9. doi: 10.1182/blood-2013-07-512194. Epub 2014 Mar 7.
896 Identification and characterization of a soluble suppressor factor(s) in the serum of AKR mice bearing lymphocytic leukemia.Cell Immunol. 1983 Nov;82(1):163-73. doi: 10.1016/0008-8749(83)90150-8.
897 Promoter analysis of TFPT (FB1), a molecular partner of TCF3 (E2A) in childhood acute lymphoblastic leukemia.Biochem Biophys Res Commun. 2001 Nov 16;288(5):1250-7. doi: 10.1006/bbrc.2001.5906.
898 Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells.Blood. 2001 Nov 1;98(9):2714-9. doi: 10.1182/blood.v98.9.2714.
899 Epigenetic regulation of putative tumor suppressor TGFBI in human leukemias.Chin Med J (Engl). 2014;127(9):1645-50.
900 The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.Genomics. 1994 Nov 15;24(2):253-8. doi: 10.1006/geno.1994.1613.
901 TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemia.J Hematol Oncol. 2016 Nov 25;9(1):128. doi: 10.1186/s13045-016-0360-4.
902 Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia.Leukemia. 2015 Dec;29(12):2317-27. doi: 10.1038/leu.2015.162. Epub 2015 Jun 25.
903 Synthesis of New Derivatives of Benzofuran as Potential Anticancer Agents.Molecules. 2019 Apr 18;24(8):1529. doi: 10.3390/molecules24081529.
904 Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types.Int J Cancer. 2004 May 1;109(5):786-92. doi: 10.1002/ijc.20041.
905 TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice.Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16600-5. doi: 10.1073/pnas.0407541101. Epub 2004 Nov 15.
906 Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function.Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6200-5. doi: 10.1073/pnas.0609174104. Epub 2007 Mar 30.
907 Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia.Clin Lymphoma Myeloma Leuk. 2015 Feb;15(2):115-127.e15. doi: 10.1016/j.clml.2014.07.011. Epub 2014 Aug 12.
908 Quantitative analysis and modeling of glucocorticoid-controlled gene expression.Pharmacogenomics. 2010 Nov;11(11):1545-60. doi: 10.2217/pgs.10.125.
909 Expression of the testis-specific gene, TSGA10, in Iranian patients with acute lymphoblastic leukemia (ALL).Leuk Res. 2006 Jul;30(7):883-9. doi: 10.1016/j.leukres.2005.11.012. Epub 2006 Jan 6.
910 Single nucleotide polymorphism of the JWA gene is associated with risk of leukemia: a case-control study in a Chinese population.J Toxicol Environ Health A. 2007 Jun;70(11):895-900. doi: 10.1080/15287390701285956.
911 Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.PLoS One. 2010 Jul 2;5(7):e11418. doi: 10.1371/journal.pone.0011418.
912 Acute myeloid leukemia with t(7;21)(q11.2;q22) expresses a novel, reversed-sequence RUNX1-DTX2 chimera.Int J Hematol. 2012 Aug;96(2):268-73. doi: 10.1007/s12185-012-1112-z. Epub 2012 Jun 4.
913 FCHSD2 predicts response to chemotherapy in acute myeloid leukemia patients.Leuk Res. 2012 Nov;36(11):1339-46. doi: 10.1016/j.leukres.2012.06.011. Epub 2012 Aug 16.
914 Posterior column ataxia with retinitis pigmentosa coexisting with sensory-autonomic neuropathy and leukemia due to the homozygous p.Pro221Ser FLVCR1 mutation.Am J Med Genet B Neuropsychiatr Genet. 2017 Oct;174(7):732-739. doi: 10.1002/ajmg.b.32570. Epub 2017 Aug 2.
915 The small leucine rich proteoglycan fibromodulin is overexpressed in human prostate epithelial cancer cell lines in culture and human prostate cancer tissue.Cancer Biomark. 2016;16(1):191-202. doi: 10.3233/CBM-150555.
916 GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome.Cancer Med. 2017 Jan;6(1):267-274. doi: 10.1002/cam4.984. Epub 2016 Nov 28.
917 EDAG-1 promotes proliferation and invasion of human thyroid cancer cells by activating MAPK/Erk and AKT signal pathways.Cancer Biol Ther. 2016 Apr 2;17(4):414-21. doi: 10.1080/15384047.2016.1156259. Epub 2016 Mar 2.
918 KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia.Blood. 2011 Apr 7;117(14):3869-80. doi: 10.1182/blood-2010-10-312736. Epub 2011 Feb 10.
919 KDM3B shows tumor-suppressive activity and transcriptionally regulates HOXA1 through retinoic acid response elements in acute myeloid leukemia.Leuk Lymphoma. 2018 Jan;59(1):204-213. doi: 10.1080/10428194.2017.1324156. Epub 2017 May 25.
920 Design, synthesis and evaluation of novel sulfonamides as potential anticancer agents.Comput Biol Chem. 2018 Jun;74:294-303. doi: 10.1016/j.compbiolchem.2018.04.006. Epub 2018 Apr 10.
921 Leukemia-related protein 16 (LRP16) promotes tumor growth and metastasis in pancreatic cancer.Onco Targets Ther. 2018 Mar 5;11:1215-1222. doi: 10.2147/OTT.S157914. eCollection 2018.
922 Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia.Oncogene. 2014 Apr 24;33(17):2169-78. doi: 10.1038/onc.2013.169. Epub 2013 Jun 3.
923 Relation of "lymphoid" phenotype and response to chemotherapy incorporating vincristine-prednisolone in the acute phase of Ph1 positive leukemia.Cancer. 1979 Feb;43(2):426-34. doi: 10.1002/1097-0142(197902)43:2<426::aid-cncr2820430204>3.0.co;2-h.
924 PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signature.J Clin Invest. 2018 Aug 1;128(8):3250-3264. doi: 10.1172/JCI99862. Epub 2018 Jul 23.
925 STAG2 loss-of-function mutation induces PD-L1 expression in U2OS cells.Ann Transl Med. 2019 Apr;7(7):127. doi: 10.21037/atm.2019.02.23.
926 Ref-1/APE1 as a Transcriptional Regulator and Novel Therapeutic Target in Pediatric T-cell Leukemia.Mol Cancer Ther. 2017 Jul;16(7):1401-1411. doi: 10.1158/1535-7163.MCT-17-0099. Epub 2017 Apr 26.
927 Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies.Cancer Res. 2008 Jun 1;68(11):4116-22. doi: 10.1158/0008-5472.CAN-08-0085.
928 TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.Cancer Discov. 2017 Nov;7(11):1336-1353. doi: 10.1158/2159-8290.CD-17-0267. Epub 2017 Oct 3.