General Information of Disease (ID: DIS32MEA)

Disease Name Congestive heart failure
Synonyms congestive heart disease; cardiac failure, congestive; weak heart; failure, congestive heart; heart failure, congestive; CHF
Disease Class BD10-BD1Z: Heart failure
Definition
Failure of the heart to pump a sufficient amount of blood to meet the needs of the body tissues, resulting in tissue congestion and edema. Signs and symptoms include shortness of breath, pitting edema, enlarged tender liver, engorged neck veins, and pulmonary rales.
Disease Hierarchy
DISDC067: Cardiac failure
DIS32MEA: Congestive heart failure
ICD Code
ICD-11
ICD-11: BD10
ICD-10
ICD-10: I50.0
ICD-9
ICD-9: 428
Expand ICD-11
'BD10.Z
Expand ICD-9
428
Disease Identifiers
MONDO ID
MONDO_0005009
UMLS CUI
C0018802
MedGen ID
9169
HPO ID
HP:0001635
SNOMED CT ID
42343007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 28 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Acetyldigitoxin DMHAUO0 Approved Small molecular drug [1]
Amiloride DMRTSGP Approved Small molecular drug [2]
Bemetizide DMQ6NN4 Approved Small molecular drug [3]
Bumetanide DMRV7H0 Approved Small molecular drug [4]
Butizide DM6MPJO Approved Small molecular drug [3]
Carperitide DMN9E53 Approved Small molecular drug [3]
Carvedilol DMHTEAO Approved Small molecular drug [5]
Chlorothiazide DMLHESP Approved Small molecular drug [6]
Cilazapril DM4V6JA Approved Small molecular drug [7]
Cyclothiazide DMJ4AWC Approved Small molecular drug [8]
Enalapril DMNFUZR Approved Small molecular drug [9]
Enalaprilat DMFYAM1 Approved NA [10]
Enoximone DMQVZJD Approved Small molecular drug [11]
Etozolin DM8EZYM Approved Small molecular drug [3]
Furosemide DMMQ8ZG Approved Small molecular drug [12]
Ha-1a DM3EVLE Approved NA [3]
Hydroflumethiazide DMVPUQI Approved Small molecular drug [13]
Inamrinone Lactate DMRMFP4 Approved Small molecular drug [3]
Levosimendan DMKBOS2 Approved Small molecular drug [14]
Liothyronine DM6IR3P Approved Small molecular drug [15]
Milrinone DM8TUPF Approved Small molecular drug [16]
Nesiritide DMFOIA8 Approved Small molecular drug [3]
Prazosin DMCD9YG Approved Small molecular drug [3]
Ramipril DM2R68E Approved Small molecular drug [17]
Spironolactone DM2AQ5N Approved Small molecular drug [18]
Torasemide DMXKJ6C Approved Small molecular drug [19]
Triamterene DM2HU9I Approved Small molecular drug [20]
Trimazosin DM1QLST Approved Small molecular drug [3]
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⏷ Show the Full List of 28 Drug(s)
This Disease is Treated as An Indication in 20 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
BB3 DMZ8AL8 Phase 3 Small molecular drug [21]
INOmax nitric oxide DM3D0KP Phase 3 NA [22]
Lixivaptan DMDN4ZP Phase 3 Small molecular drug [23]
RT-100 DM3HKRH Phase 3 NA [24]
WC-3049 DM1XOC1 Phase 3 NA [25]
MyoCell DMUB2OM Phase 2/3 NA [26]
3,5-diiodothyropropionic acid DML8M5T Phase 2 Small molecular drug [27]
IK-5001 DMY6SI3 Phase 2 NA [28]
Long-actingloop diuretic DMAHRY7 Phase 2 NA [24]
NAN-101 DMXRPUF Phase 2 Gene therapy [29]
PL-3394 DMC1SOS Phase 2 NA [30]
PL-3994 DMHUCQS Phase 2 NA [31]
T2c-001 DM06GDC Phase 2 NA [32]
Urocortin 2 DM0YO4Q Phase 2 NA [33]
AdipoCell DM347BM Phase 1/2 NA [24]
GGF DMVWYOU Phase 1b NA [34]
Myoblast cell transplantation therapy DMKRJUE Phase 1 NA [35]
REC-02 DMHT5XV Phase 1 NA [24]
RWJ-676070 DMWSTGV Phase 1 NA [36]
SER-101 DMTZ983 Phase 1 NA [37]
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⏷ Show the Full List of 20 Drug(s)
This Disease is Treated as An Indication in 1 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Ticrynafen DMLFSTR Withdrawn from market Small molecular drug [3]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 3 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
CLP-1002 DMDJS9O Investigative NA [38]
Gene therapy, congestive heart failure DM8O5FO Investigative NA [38]
SL125 DMEIZ20 Investigative NA [39]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 452 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ANGPT2 TTKLQTJ Limited Biomarker [40]
APLNR TTJ8E43 Limited Biomarker [41]
CAT TTPS279 Limited Biomarker [42]
CSF2 TTNYZG2 Limited Biomarker [43]
CYP11B2 TT9MNE2 Limited Biomarker [44]
ELAVL1 TTPC9D0 Limited Biomarker [45]
HCN4 TTQP04A Limited Biomarker [46]
IL17A TTG0MT6 Limited Altered Expression [47]
IL18 TTRICUF Limited Altered Expression [48]
KNG1 TTDJ4MY Limited Biomarker [49]
LEP TTBJEZ5 Limited Altered Expression [50]
MAPK14 TTQBR95 Limited Altered Expression [42]
MMP2 TTLM12X Limited Altered Expression [51]
MYBPC3 TT9WOBN Limited Genetic Variation [52]
MYH7 TTNIMDP Limited Genetic Variation [53]
NPPC TTRK0B9 Limited Biomarker [54]
PIK3CB TT9H4P3 Limited Altered Expression [55]
PPARA TTJ584C Limited Biomarker [56]
PPARG TTT2SVW Limited Altered Expression [57]
PRKCA TTFJ8Q1 Limited Genetic Variation [58]
SLC8A1 TTCF82X Limited Biomarker [59]
XDH TT7RJY8 Limited Biomarker [60]
ACKR3 TTRQJTC Disputed Biomarker [61]
ADRA1A TTNGILX Disputed Biomarker [61]
ADRA2B TTWM4TY Disputed Biomarker [61]
ANGPT1 TTWNQ1T Disputed Biomarker [62]
BRS3 TTKYEPM Disputed Biomarker [61]
CALCR TTLWS2O Disputed Biomarker [63]
CXCR6 TT2BVUA Disputed Biomarker [61]
GRK5 TTTCXO0 Disputed Altered Expression [61]
LPAR2 TTB7Y8I Disputed Biomarker [61]
SLC6A8 TTYUHB5 Disputed Biomarker [63]
SSTR4 TTAE1BR Disputed Biomarker [61]
TTR TTPOYU7 Disputed Biomarker [64]
VEGFB TTPJQHE Disputed Biomarker [65]
ADAM17 TT6AZXG moderate Biomarker [66]
BMP10 TTTG6H1 moderate Biomarker [67]
GATA4 TT1VDN2 moderate Altered Expression [68]
HSF1 TTN6STZ moderate Altered Expression [69]
MAS1 TTOISYB moderate Biomarker [61]
NPR3 TTWVLS6 moderate Biomarker [54]
NR3C1 TTOZRK6 moderate Biomarker [70]
POSTN TT8ALTZ moderate Biomarker [71]
PRKCB TTYPXQF moderate Altered Expression [72]
PRKD1 TTSLUMT moderate Biomarker [73]
PSEN2 TTWN3F4 moderate Genetic Variation [74]
SIRT3 TTVZLIJ moderate Biomarker [75]
UTRN TTNO1VA moderate Biomarker [76]
ABCA4 TTLB52K Strong Biomarker [77]
ABCC8 TTP835K Strong Biomarker [78]
ABCC9 TTEF5MJ Strong Biomarker [78]
ACLY TT0Z6Y2 Strong Biomarker [79]
ACR TTAHE2N Strong Biomarker [80]
ACVRL1 TTGYPTC Strong Biomarker [81]
ADCYAP1R1 TT5OREU Strong Biomarker [82]
ADIPOQ TTXKA7D Strong Altered Expression [83]
ADM2 TTM642F Strong Biomarker [84]
ADORA1 TTK25J1 Strong Biomarker [85]
ADORA2A TTM2AOE Strong Genetic Variation [86]
ADORA2B TTNE7KG Strong Altered Expression [87]
ADORA3 TTJFY5U Strong Genetic Variation [88]
ADRB3 TTMXGCW Strong Biomarker [89]
AGRP TT4DE1O Strong Biomarker [90]
AHSG TTKF4WV Strong Altered Expression [91]
AIMP2 TTXWHGF Strong Altered Expression [42]
AKR1B1 TTFBNVI Strong Genetic Variation [92]
ALB TTFNGC9 Strong Biomarker [93]
ALDH2 TTFLN4T Strong Biomarker [94]
ALOX15 TTN9T81 Strong Biomarker [95]
AMACR TTLN1AP Strong Biomarker [96]
ANG TTURHFP Strong Biomarker [97]
ANXA5 TT2Z83I Strong Biomarker [98]
APCS TTB7VAT Strong Biomarker [99]
APLN TT87D3J Strong Altered Expression [41]
ARRB1 TTMVD4A Strong Therapeutic [100]
ARRB2 TT8SO2I Strong Biomarker [101]
ARSB TTESQTG Strong Biomarker [102]
ASIC1 TTRJYB6 Strong Biomarker [103]
ATG7 TTLVB9Z Strong Biomarker [104]
AVP TTJ8EWH Strong Biomarker [101]
AVPR1A TT4TFGN Strong Altered Expression [105]
AVPR1B TTL9MHW Strong Altered Expression [105]
AVPR2 TTK8R02 Strong Biomarker [106]
AXL TTZPY6J Strong Altered Expression [107]
BACE1 TTJUNZF Strong Altered Expression [108]
BAX TTQ57WJ Strong Altered Expression [109]
BGN TT0JPVF Strong Biomarker [110]
BIRC2 TTQ5LRD Strong Altered Expression [111]
BMPR2 TTGKF90 Strong Altered Expression [112]
BRD1 TTT09OB Strong Biomarker [113]
BSG TT5UJWD Strong Biomarker [114]
C3AR1 TTI6B3F Strong Biomarker [115]
CA3 TTXUK5D Strong Biomarker [116]
CAD TT2YT1K Strong Biomarker [117]
CALCRL TTY6O0Q Strong Altered Expression [118]
CALR TTUZ7OA Strong Biomarker [63]
CAPN1 TT1WBIJ Strong Biomarker [119]
CASP2 TT12VNG Strong Biomarker [120]
CASP3 TTPF2QI Strong Biomarker [121]
CASR TTBUYHA Strong Altered Expression [122]
CCL21 TTLZK1U Strong Altered Expression [123]
CCN2 TTIL516 Strong Altered Expression [124]
CCR2 TTFZYTO Strong Biomarker [125]
CD34 TTZAVYN Strong Biomarker [126]
CD36 TTPJMCU Strong Altered Expression [127]
CD59 TTBGTEJ Strong Biomarker [128]
CD69 TTPQE9F Strong Biomarker [129]
CD70 TTNCIE0 Strong Biomarker [130]
CDK8 TTBJR4L Strong Altered Expression [131]
CDK9 TT1LVF2 Strong Biomarker [132]
CEP290 TT3XBOV Strong Genetic Variation [133]
CETP TTFQAYR Strong Biomarker [134]
CFD TT8D13I Strong Biomarker [135]
CFLAR TTJZQYH Strong Biomarker [136]
CGB3 TTUH273 Strong Altered Expression [137]
CHRM2 TTYEG6Q Strong Altered Expression [138]
CLCN3 TT8XNZ7 Strong Biomarker [139]
CLCNKA TT823N1 Strong Genetic Variation [140]
CNP TT71P0H Strong Biomarker [141]
COX17 TT0F26C Strong Altered Expression [124]
CPB1 TT4UJX5 Strong Biomarker [142]
CPT1B TTDL0NY Strong Altered Expression [143]
CRAT TTC8M31 Strong Altered Expression [144]
CRHR1 TT7EFHR Strong Biomarker [145]
CRHR2 TTIY658 Strong Biomarker [146]
CRK TTFEUYR Strong Altered Expression [42]
CS TTZA6B3 Strong Altered Expression [147]
CSE1L TTTRULD Strong Biomarker [148]
CSF3 TT5TQ2W Strong Biomarker [149]
CTF1 TTXGTZU Strong Biomarker [150]
CTH TTLQUZS Strong Biomarker [151]
CTSG TTQAJF1 Strong Biomarker [152]
CTSK TTDZN01 Strong Biomarker [153]
CTSS TTUMQVO Strong Genetic Variation [154]
CX3CR1 TT2T98G Strong Altered Expression [155]
CXCL2 TTZF0K2 Strong Biomarker [156]
CYBB TT5T8MR Strong Biomarker [157]
CYP11B1 TTIQUX7 Strong Biomarker [158]
CYP2D6 TTVG215 Strong Biomarker [159]
CYP2J2 TTNE1C7 Strong Biomarker [160]
CYP3A5 TTHS0OK Strong Genetic Variation [161]
DBH TTYIP79 Strong Altered Expression [162]
DDIT4 TTVEOY6 Strong Biomarker [163]
DDR1 TTI1FPZ Strong Biomarker [164]
DGAT1 TT0GV3R Strong Biomarker [165]
DMPK TTZQTY2 Strong Biomarker [166]
DNASE1 TTYWGOJ Strong Biomarker [167]
DNM2 TTVRA5G Strong Biomarker [168]
DPP10 TTOVUPC Strong Altered Expression [169]
DPP9 TTNDUL7 Strong Biomarker [170]
DYSF TTA7MXQ Strong Biomarker [171]
ECE1 TTQ9RYT Strong Biomarker [172]
EDNRA TTKRD0G Strong Biomarker [61]
EDNRB TT3ZTGU Strong Biomarker [173]
EGLN1 TT9ISBX Strong Altered Expression [174]
ENAH TTY36UA Strong Altered Expression [175]
ENG TTB30LE Strong Altered Expression [176]
ENPEP TT9PBIL Strong Biomarker [177]
EPHX2 TT7WVHI Strong Biomarker [178]
ERBB4 TTWALCO Strong Genetic Variation [179]
ERN1 TTKIAT3 Strong Biomarker [180]
ESRRA TTPNQAC Strong Biomarker [181]
F10 TTCIHJA Strong Biomarker [182]
F2RL1 TTQR74A Strong Altered Expression [183]
F8 TT1290U Strong Biomarker [184]
FABP3 TT3TGLR Strong Biomarker [185]
FABP4 TTHWMFZ Strong Biomarker [186]
FASLG TTO7014 Strong Therapeutic [187]
FASN TT7AOUD Strong Biomarker [79]
FDPS TTIKWV4 Strong Biomarker [188]
FDXR TT3W4IX Strong Genetic Variation [92]
FFAR4 TT08JVB Strong Biomarker [189]
FGF4 TTCEKVZ Strong Biomarker [190]
FGFR4 TT1KX2S Strong Biomarker [191]
FKBP1A TTMW94E Strong Biomarker [192]
FLNA TTSTRZY Strong Biomarker [193]
FOS TTOM5AU Strong Biomarker [194]
FST TTDNM9W Strong Biomarker [195]
FSTL3 TTWRPM8 Strong Biomarker [196]
FURIN TTH9WF6 Strong Biomarker [197]
GABRA1 TT1MPAY Strong Altered Expression [198]
GAD1 TTKGEP3 Strong Altered Expression [198]
GAL TTXZAJ5 Strong Biomarker [199]
GAS6 TT69QD2 Strong Biomarker [200]
GCH1 TTLSWP6 Strong Altered Expression [201]
GDF2 TTAP4T1 Strong Altered Expression [176]
GHRL TT1OCL0 Strong Biomarker [202]
GHSR TTWDC17 Strong Altered Expression [138]
GNAQ TTL1SRG Strong Altered Expression [203]
GP1BA TTVB0Q9 Strong Biomarker [204]
GP6 TTTJUVZ Strong Biomarker [204]
GPBAR1 TTSDVTR Strong Biomarker [205]
GPR17 TTMPART Strong Biomarker [206]
GPR32 TT7OCUB Strong Altered Expression [207]
GPR35 TT254XD Strong Biomarker [208]
GPRC6A TTI1PRE Strong Biomarker [209]
GRIN1 TTLD29N Strong Altered Expression [210]
GRK3 TT5A4DX Strong Biomarker [211]
GSK3A TTQWAU1 Strong Biomarker [212]
GSK3B TTRSMW9 Strong Biomarker [213]
GSN TTUH7OM Strong Biomarker [214]
GSR TTEP6RV Strong Biomarker [215]
GUSB TTHS7CM Strong Biomarker [216]
HCN2 TT9EUT4 Strong Biomarker [217]
HDAC5 TTUELN5 Strong Altered Expression [218]
HDC TTV9GOF Strong Biomarker [219]
HIF1A TTSN6QU Strong Biomarker [220]
HIPK2 TTOB49C Strong Biomarker [221]
HK2 TTK02H8 Strong Altered Expression [222]
HLA-DRB1 TTUXSTW Strong Genetic Variation [223]
HMBS TTT0HW3 Strong Biomarker [224]
HMGB1 TTWQYB7 Strong Altered Expression [225]
HMGB2 TTA78JQ Strong Altered Expression [226]
HMOX1 TTI6V2A Strong Biomarker [227]
HP TTLC8E1 Strong Therapeutic [228]
HRC TTR4FKD Strong Genetic Variation [229]
HRH3 TT9JNIC Strong Genetic Variation [230]
HSD11B1 TTN7BL9 Strong Biomarker [231]
HSPB1 TT9AZWY Strong Biomarker [232]
HTR2A TTJQOD7 Strong Biomarker [233]
HTR2B TT0K1SC Strong Biomarker [234]
HTR4 TT07C3Y Strong Biomarker [233]
ID2 TTW8A5N Strong Genetic Variation [235]
IGF1 TTT6LOU Strong Biomarker [236]
IGFBP5 TTDWEA8 Strong Altered Expression [237]
IGFBP7 TTUQ01B Strong Biomarker [238]
IL13RA1 TTNEAMG Strong Biomarker [239]
IL1R2 TT51DEV Strong Biomarker [240]
IL1RL1 TT4GZA4 Strong Biomarker [241]
IL33 TT5MD4P Strong Biomarker [242]
IL6 TTT1V78 Strong Biomarker [243]
ILK TT7ALZG Strong Biomarker [244]
INS TTZOPHG Strong Biomarker [245]
IRF1 TT4TU3L Strong Biomarker [246]
ISG15 TTVOH3T Strong Biomarker [247]
ITGB1 TTBVIQC Strong Biomarker [248]
ITPR1 TT5HWAT Strong Biomarker [249]
ITPR2 TTK9OV3 Strong Altered Expression [250]
ITPR3 TTH1769 Strong Altered Expression [251]
KCNA2 TTVFB0O Strong Biomarker [252]
KCND3 TTPLQO0 Strong Biomarker [253]
KCNH2 TTQ6VDM Strong Biomarker [254]
KCNK3 TTGR91N Strong Biomarker [255]
KCNN4 TT7M9I6 Strong Genetic Variation [256]
KCNQ1 TT846HF Strong Biomarker [257]
KCNT1 TTGJFK1 Strong Genetic Variation [258]
LAMP2 TTULDG7 Strong Biomarker [259]
LCAT TTGZ91P Strong Biomarker [134]
LILRB4 TTREOKA Strong Biomarker [260]
LIMK1 TTWL9TY Strong Biomarker [261]
LONP1 TTM1VPZ Strong Biomarker [262]
LOX TTQHNAM Strong Biomarker [263]
LPA TTU9LGY Strong Biomarker [264]
LPAR3 TTE2YJR Strong Biomarker [209]
LTA TTP73TM Strong Genetic Variation [265]
LY75 TTG180Q Strong Biomarker [266]
MANF TT56RYE Strong Biomarker [267]
MAOA TT3WG5C Strong Biomarker [268]
MAP2K7 TT6QY3J Strong Biomarker [269]
MAP3K11 TTETX6Q Strong Biomarker [270]
MAP3K20 TTTUZ3O Strong Biomarker [271]
MAP3K5 TTOQCD8 Strong Biomarker [272]
MAPK9 TT3IVG2 Strong Biomarker [271]
MC4R TTD0CIQ Strong Genetic Variation [273]
MECP2 TTTAU9R Strong Altered Expression [274]
MGAT1 TTYJRN5 Strong Genetic Variation [275]
MRGPRX1 TTIX6PK Strong Biomarker [209]
MS4A1 TTUE541 Strong Biomarker [276]
MSTN TTM8I2X Strong Altered Expression [277]
MTTP TTUS1RD Strong Biomarker [278]
MUC16 TTC1PS3 Strong Biomarker [279]
MYLK TT18ETS Strong Altered Expression [280]
NAGLU TTDM6HZ Strong Genetic Variation [281]
NCAM1 TTVXPHT Strong Biomarker [282]
NCF1 TTZ4JC3 Strong Biomarker [283]
NNT TTKIH76 Strong Genetic Variation [284]
NOD1 TTYSRXM Strong Biomarker [285]
NOS2 TTF10I9 Strong Altered Expression [286]
NOX4 TTQRBSJ Strong Biomarker [287]
NPR1 TTM9IYA Strong Biomarker [288]
NPR2 TTNB7IF Strong Biomarker [289]
NPSR1 TTV1C0Z Strong Biomarker [290]
NPY TT64REZ Strong Biomarker [291]
NPY4R TTW4N16 Strong Altered Expression [292]
NR1H3 TTECBXN Strong Biomarker [293]
NR1H4 TTS4UGC Strong Altered Expression [294]
NR4A1 TTMXE2Q Strong Biomarker [291]
NT5E TTK0O6Y Strong Biomarker [295]
OGDH TTH8T6I Strong Altered Expression [296]
OLR1 TTKSND3 Strong Biomarker [297]
OPA1 TTTU49Q Strong Biomarker [127]
OPRD1 TT27RFC Strong Biomarker [298]
OSM TTIVXSE Strong Altered Expression [299]
OXER1 TT7WBSV Strong Biomarker [209]
OXGR1 TTAS1QK Strong Biomarker [300]
P2RX1 TTJW7B3 Strong Altered Expression [301]
P2RX3 TT2THBD Strong Altered Expression [301]
P2RX4 TT1NLOA Strong Altered Expression [301]
P2RX7 TT473XN Strong Altered Expression [301]
P2RY1 TTA93TL Strong Altered Expression [301]
P2RY12 TTZ1DT0 Strong Biomarker [302]
P2RY2 TTOZHQC Strong Altered Expression [301]
P2RY4 TT24DGP Strong Altered Expression [303]
P2RY6 TTNVSKA Strong Altered Expression [303]
PAM TTF4ZPC Strong Biomarker [304]
PARP1 TTVDSZ0 Strong Biomarker [305]
PCSK6 TT75LN9 Strong Biomarker [306]
PCSK9 TTNIZ2B Strong Biomarker [307]
PDE10A TTJW4LU Strong Biomarker [308]
PDE1C TTW2HRK Strong Genetic Variation [309]
PDE3A TT06AWU Strong Altered Expression [310]
PDE4A TTZ97H5 Strong Biomarker [311]
PDE4D TTSKMI8 Strong Altered Expression [310]
PDE5A TTJ0IQB Strong Altered Expression [312]
PDE9A TTZOEBC Strong Altered Expression [313]
PDGFRA TT8FYO9 Strong Biomarker [314]
PDK1 TTCZOF2 Strong Genetic Variation [315]
PDPK1 TTYMGWX Strong Biomarker [316]
PEBP1 TT1BGU8 Strong Biomarker [317]
PF4 TTSG7Q5 Strong Altered Expression [318]
PGF TT48I1Y Strong Biomarker [319]
PIK3CG TTHBTOP Strong Altered Expression [55]
PIM1 TTTN5QW Strong Biomarker [262]
PIN1 TTJNTSI Strong Altered Expression [320]
PKN1 TTSL41O Strong Biomarker [321]
PKN2 TTTHO0M Strong Biomarker [321]
PLAT TTXAGYU Strong Biomarker [156]
PNMT TT0NZIC Strong Biomarker [322]
POMC TT21AKM Strong Biomarker [323]
PON1 TT9LX82 Strong Biomarker [324]
PPARGC1B TTKSQ3W Strong Altered Expression [325]
PPIA TTL2ADK Strong Biomarker [326]
PPID TTNAFOU Strong Biomarker [327]
PPIF TTRFQTB Strong Biomarker [327]
PPP3CA TTA4LDE Strong Biomarker [328]
PRKAR2B TTW4Y2M Strong Biomarker [79]
PRMT1 TTVOJAI Strong Biomarker [329]
PROC TTZUXYS Strong Biomarker [55]
PRTN3 TT5MLC4 Strong Biomarker [330]
PSEN1 TTZ3S8C Strong Altered Expression [331]
PTGER3 TTPNGDE Strong Biomarker [198]
PTGER4 TT79WV3 Strong Biomarker [332]
PTGS1 TT8NGED Strong Biomarker [333]
PTGS2 TTVKILB Strong Biomarker [334]
PTH TT6F7GZ Strong Biomarker [335]
PTK2B TTTEFBV Strong Biomarker [336]
PTPN1 TTELIN2 Strong Biomarker [337]
RAC1 TT2M9CG Strong Biomarker [338]
RACK1 TTJ10AL Strong Biomarker [339]
RAPGEF3 TTOE7I0 Strong Biomarker [340]
RBP4 TT0C8BY Strong Biomarker [341]
RGS2 TTKB7T3 Strong Biomarker [342]
RGS4 TTGTKX9 Strong Altered Expression [343]
RHD TTLCKI8 Strong Genetic Variation [344]
RHO TTH0KSX Strong Biomarker [280]
RICTOR TT143WL Strong Biomarker [345]
ROCK1 TTZN7RP Strong Altered Expression [261]
ROCK2 TTGWKQJ Strong Biomarker [346]
RORC TTGV6LY Strong Biomarker [347]
RPGR TTHBDA9 Strong Biomarker [348]
RYR1 TTU5CIX Strong Biomarker [349]
S1PR1 TT9JZCK Strong Genetic Variation [350]
SCD TT6RIOV Strong Biomarker [351]
SCN10A TT90XZ8 Strong Biomarker [352]
SCN5A TTZOVE0 Strong Altered Expression [353]
SELP TTE5VG0 Strong Altered Expression [155]
SEMA4D TT5UT28 Strong Biomarker [354]
SERPINE1 TTTO43N Strong Biomarker [110]
SF3B1 TTL2WUI Strong Biomarker [355]
SGCA TTS9Q5V Strong Biomarker [356]
SGK1 TTTV8EJ Strong Biomarker [357]
SHCBP1 TTZ9WGL Strong Biomarker [304]
SIRT1 TTUF2HO Strong Biomarker [358]
SIRT6 TTUXYWF Strong Biomarker [359]
SLC17A5 TTFSUIA Strong Altered Expression [360]
SLC18A3 TTV8KWS Strong Altered Expression [361]
SLC2A4 TTP6MT5 Strong Altered Expression [362]
SLC30A8 TTXIGT7 Strong Altered Expression [72]
SLC33A1 TTL69WB Strong Biomarker [363]
SLC5A1 TT2UE56 Strong Biomarker [364]
SLC6A2 TTAWNKZ Strong Genetic Variation [365]
SLC7A1 TT4S150 Strong Altered Expression [144]
SLC9A1 TTGSEFH Strong Biomarker [366]
SLC9A3 TTFZVPO Strong Biomarker [367]
SLCO1B1 TTFGXEB Strong Genetic Variation [368]
SLCO1B3 TTU86P0 Strong Genetic Variation [368]
SMPD2 TTE5VI6 Strong Biomarker [369]
SOD1 TTP9K3Q Strong Biomarker [42]
SPTBN1 TTS9BDA Strong Biomarker [370]
SRGN TTCHB06 Strong Biomarker [371]
STC1 TTDLUER Strong Altered Expression [372]
STC2 TT4EFTR Strong Biomarker [373]
SUGT1 TT7Q9WR Strong Biomarker [374]
TAGLN TTDRZ9H Strong Altered Expression [174]
TCL1A TTUKRDV Strong Altered Expression [375]
TERF2 TT5XSLT Strong Biomarker [376]
TH TTUHP71 Strong Biomarker [377]
THRA TTTSEPU Strong Biomarker [378]
TLR2 TTY7ZHS Strong Biomarker [379]
TMSB4X TTMVAIU Strong Biomarker [380]
TNFRSF10B TTW20TU Strong Biomarker [195]
TNFRSF11B TT2CJ75 Strong Biomarker [195]
TNFRSF12A TTKPS7V Strong Altered Expression [381]
TNFRSF1A TTG043C Strong Biomarker [382]
TNFSF12 TTBTDM1 Strong Altered Expression [381]
TNNC1 TT8RDXP Strong Biomarker [383]
TNNT2 TTWAS18 Strong Biomarker [384]
TOP2B TT4NVEM Strong Biomarker [385]
TPCN1 TTODQE2 Strong Altered Expression [249]
TPCN2 TTHQJ2Y Strong Altered Expression [249]
TPH2 TT3KLDP Strong Genetic Variation [386]
TRAF6 TTCDR6M Strong Biomarker [387]
TRIM37 TTAMCSL Strong Genetic Variation [388]
TRPA1 TTELV3W Strong Altered Expression [389]
TRPC1 TTA76X0 Strong Biomarker [390]
TRPC6 TTRBT3W Strong Altered Expression [391]
TRPM4 TTJ2HKA Strong Biomarker [392]
TRPV1 TTMI6F5 Strong Biomarker [393]
TRPV2 TTBECWA Strong Altered Expression [394]
TRPV6 TTBK14N Strong Altered Expression [144]
TSPO TTPTXIN Strong Biomarker [395]
TXN TTZJ5U9 Strong Biomarker [396]
TXNRD3 TTDYFVB Strong Biomarker [397]
UCP1 TTI12YJ Strong Biomarker [398]
UCP3 TT12RJK Strong Biomarker [399]
UTS2R TTW5UDX Strong Biomarker [400]
VCP TTHNLSB Strong Biomarker [401]
VEGFA TT3LJ9K Strong Biomarker [402]
VEGFD TTOM5H4 Strong Genetic Variation [403]
VKORC1 TTEUC8H Strong Genetic Variation [404]
VWF TT3SZBT Strong Biomarker [405]
ALOX12 TT12ABZ Definitive Biomarker [406]
BECN1 TT5M7LN Definitive Therapeutic [407]
BIRC5 TTTPU1G Definitive Biomarker [408]
CHRM4 TTQ3JTF Definitive Biomarker [164]
CHRNA4 TT4H1MQ Definitive Biomarker [164]
DNMT1 TT6S2FE Definitive Biomarker [409]
FAS TT7LTUJ Definitive Therapeutic [187]
FOSL1 TTY8LZG Definitive Biomarker [194]
FTH1 TT975ZT Definitive Biomarker [410]
GJA1 TT4F7SL Definitive Posttranslational Modification [411]
LIF TTGZ5WN Definitive Biomarker [412]
MMP13 TTHY57M Definitive ModifyingMutation [413]
MMP14 TTJ4QE7 Definitive ModifyingMutation [413]
MMP8 TTGA1IV Definitive ModifyingMutation [413]
NGFR TTEDJN4 Definitive Biomarker [164]
PLD2 TTRLMKF Definitive Biomarker [414]
ROS1 TTSZ6Y3 Definitive Biomarker [415]
SCN8A TT54ERL Definitive Biomarker [416]
TNNI3 TTNLDK6 Definitive Biomarker [417]
TRPC3 TTNVC34 Definitive Biomarker [358]
UCP2 TTSC2YM Definitive Biomarker [418]
------------------------------------------------------------------------------------
⏷ Show the Full List of 452 DTT(s)
This Disease Is Related to 16 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCB7 DT2IMBW Strong Biomarker [419]
KCNK2 DTENHUP Strong Biomarker [420]
SLC12A2 DTHKL3Q Strong Biomarker [421]
SLC22A4 DT2EG60 Strong Biomarker [240]
SLC22A5 DT3HUVD Strong Genetic Variation [422]
SLC24A3 DTO18LP Strong Biomarker [423]
SLC27A6 DTG4CWJ Strong Genetic Variation [424]
SLC30A10 DTYBI73 Strong Altered Expression [72]
SLC35A1 DTVZIRG Strong Biomarker [425]
SLC39A14 DTZ6IJW Strong Altered Expression [72]
SLC39A8 DTLPQGT Strong Altered Expression [72]
SLC4A1 DTB0Q3P Strong Biomarker [426]
SLC4A3 DT4X2AH Strong Biomarker [427]
SLC52A1 DT7NOKR Strong Altered Expression [428]
SLC9A6 DTN0JXW Strong Biomarker [90]
SLC9C1 DT9J8DO Strong Biomarker [429]
------------------------------------------------------------------------------------
⏷ Show the Full List of 16 DTP(s)
This Disease Is Related to 23 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
CHDH DEAHED0 Limited Biomarker [430]
ACP5 DESITDW Strong Genetic Variation [431]
ACSS2 DEE76VW Strong Biomarker [432]
ALAS2 DE437BY Strong Altered Expression [433]
APRT DE2MV1R Strong Biomarker [434]
CBR3 DEIVKZ8 Strong Genetic Variation [435]
CMPK1 DEMPH4I Strong Biomarker [436]
CRMP1 DE0EUXB Strong Biomarker [76]
CYP4F3 DEFCMPI Strong Biomarker [437]
DDAH1 DEY0TQC Strong Biomarker [438]
FXN DEXVHDB Strong Biomarker [439]
MAT2B DEKF1OH Strong Biomarker [397]
ME1 DE97WM8 Strong Altered Expression [440]
NNMT DECVGJ3 Strong Biomarker [441]
NT5C2 DE1DOKJ Strong Biomarker [442]
OPLAH DEJ1LMB Strong Biomarker [443]
PCK1 DEPLH5Z Strong Biomarker [79]
PON2 DEHJU7E Strong Biomarker [444]
SAT1 DEMWO83 Strong Biomarker [445]
SULT1E1 DESTKG6 Strong Biomarker [446]
SULT2A1 DE0P6LK Strong Biomarker [447]
UGT2B7 DEB3CV1 Strong Biomarker [448]
DIO3 DET89OV Definitive Biomarker [449]
------------------------------------------------------------------------------------
⏷ Show the Full List of 23 DME(s)
This Disease Is Related to 546 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AMPD1 OTU17BCI Limited Genetic Variation [450]
BAMBI OTCEJ8W5 Limited Biomarker [346]
CHGA OTXYX5JH Limited Biomarker [425]
DECR1 OTCDIR6X Limited Biomarker [377]
DNAH8 OTGES2OU Limited Genetic Variation [85]
DSTN OTMXO4YB Limited Biomarker [346]
FSD1 OT8P6PT3 Limited Biomarker [451]
FSD1L OTBQ48RF Limited Biomarker [451]
IGFBP4 OT2HZRBD Limited Biomarker [373]
MTPN OT5N60RU Limited Biomarker [452]
PITX2 OTWMXAOY Limited Genetic Variation [453]
RLN2 OTY3OG71 Limited Biomarker [454]
SOX4 OTSS40SS Limited Biomarker [346]
TBX20 OTMPU2XQ Limited Biomarker [346]
GPR42 OTEB0ROY Disputed Biomarker [61]
REG1A OTMHUH1D Disputed Genetic Variation [455]
S100A1 OT1F2G4J Disputed Biomarker [456]
TM7SF2 OTILU5S7 Disputed Biomarker [62]
ANKRD1 OTHJ7JV9 moderate Biomarker [457]
ATP6AP2 OT0IABVV moderate Biomarker [458]
CASQ2 OT09MNQ8 moderate Genetic Variation [459]
CLIC2 OTDBURM4 moderate Genetic Variation [460]
COX2 OTTMVBJJ moderate Biomarker [334]
EYA4 OTINGR3Z moderate Altered Expression [461]
HAVCR1 OT184CRZ moderate Biomarker [462]
IL6ST OT1N9C70 moderate Biomarker [463]
MEF2A OTV2SF6E moderate Biomarker [464]
PVALB OTZW1WVQ moderate Biomarker [465]
SGCD OTRBL3NQ moderate Genetic Variation [466]
TOR2A OT1EGCDU moderate Altered Expression [467]
ACACA OT5CQPZY Strong Biomarker [468]
ACADM OTA4P0FC Strong Altered Expression [143]
ACADS OTGFANYQ Strong Biomarker [469]
ACCS OTHIHI9D Strong Biomarker [432]
ACSL5 OT3L9XO3 Strong Genetic Variation [470]
ACSL6 OT0TT8P8 Strong Genetic Variation [470]
ACTC1 OTJU04B1 Strong Genetic Variation [471]
ACTN3 OT9DZ7JQ Strong Genetic Variation [472]
ADAMTS16 OTTKUH99 Strong Altered Expression [51]
ADCY10 OTYSTB0R Strong Biomarker [473]
ADCY6 OTFOY4WW Strong Biomarker [474]
ADD1 OTTF68DC Strong Genetic Variation [475]
ADI1 OT8IOD03 Strong Genetic Variation [476]
ADIPOR1 OT65ZFZN Strong Biomarker [477]
ADIPOR2 OT2HDTL8 Strong Biomarker [477]
ADO OTRLGQ7V Strong Biomarker [478]
AFDN OTTRU341 Strong Biomarker [479]
AGGF1 OTA7U2T8 Strong Biomarker [480]
AGXT2 OTO6QUTM Strong Genetic Variation [481]
AHSA1 OTC7AFHT Strong Altered Expression [42]
AHSP OTTHBSUS Strong Biomarker [482]
AK3 OTM59ZGG Strong Genetic Variation [483]
AK6 OT84OHHP Strong Genetic Variation [484]
AKAP1 OTIIB2JB Strong Biomarker [485]
AKAP12 OTCVRDDX Strong Biomarker [486]
ALDH7A1 OTV57BZD Strong Biomarker [487]
ALYREF OTOF2ADD Strong Biomarker [488]
AMBP OTLU8GU8 Strong Biomarker [309]
AMZ1 OTDH9XM0 Strong Biomarker [489]
ANGPTL2 OTB6JG41 Strong Biomarker [490]
ANK2 OTWB4R1Y Strong Altered Expression [491]
ANXA6 OT9KIQ0Y Strong Altered Expression [492]
APIP OT8ZABOU Strong Altered Expression [87]
APOC1 OTA58CED Strong Biomarker [79]
APOF OT12S5QS Strong Biomarker [493]
AQP2 OTQLBKK6 Strong Biomarker [494]
ARC OTN2QQPG Strong Biomarker [495]
ARHGEF5 OTUVGFT9 Strong Biomarker [462]
ARID1B OTILK3Q7 Strong Genetic Variation [496]
ARID3A OTZZ4SFP Strong Genetic Variation [496]
ARSD OTAHW9M8 Strong Biomarker [497]
ARSL OTF1VTCR Strong Biomarker [498]
ARTN OTWIWGL6 Strong Biomarker [90]
ASB14 OTQT4M45 Strong Biomarker [246]
ASXL1 OTX931AW Strong Biomarker [355]
ATP1A3 OTM8EG6H Strong Biomarker [499]
ATP2A1 OT959A3A Strong Biomarker [500]
ATP2A3 OTFYDEES Strong Biomarker [501]
ATP2B4 OTMWFDAC Strong Biomarker [502]
ATP5F1A OT3FZDLX Strong Biomarker [423]
ATP5PF OTDAE8FP Strong Biomarker [503]
ATXN1 OTQF0HNR Strong Biomarker [121]
ATXN7 OTL3YF1H Strong Biomarker [504]
AZIN2 OT8OB7CG Strong Biomarker [505]
AZU1 OTHXU264 Strong Biomarker [506]
BCAR1 OTKT2C2N Strong Biomarker [148]
BCL2L12 OTS6IFZY Strong Altered Expression [507]
BDH1 OT62RL5P Strong Biomarker [508]
BEX1 OTBQIF0H Strong Altered Expression [509]
BFAR OTTBG0V7 Strong Altered Expression [294]
BGLAP OTK1YLWQ Strong Altered Expression [510]
BIN1 OTK8O0X8 Strong Biomarker [511]
BIRC6 OTCQJAB0 Strong Genetic Variation [512]
BMPR1A OTQOA4ZH Strong Altered Expression [513]
BMS1 OTEGQ8ZO Strong Biomarker [468]
BNIP3 OT4SO7J4 Strong Biomarker [514]
BNIP3L OTJKOMXE Strong Altered Expression [515]
BTBD8 OT3A3RD7 Strong Genetic Variation [516]
BTD OTJYTQ69 Strong Biomarker [517]
BVES OT4GT1WC Strong Altered Expression [518]
C1QTNF1 OT7I7KHC Strong Biomarker [519]
C1QTNF9 OTLI3VA3 Strong Biomarker [520]
CABIN1 OT4G5CIK Strong Altered Expression [521]
CACNG6 OT2PC1E1 Strong Biomarker [522]
CALCOCO2 OTRGX0OV Strong Biomarker [523]
CAMK2D OTJ5XLVU Strong Biomarker [524]
CAPG OTJ86KI6 Strong Biomarker [525]
CASP8AP2 OTTWT68S Strong Biomarker [526]
CAST OTBXZZGF Strong Genetic Variation [527]
CASZ1 OTWJ2OR8 Strong Biomarker [425]
CAV3 OTWSFDB4 Strong Altered Expression [528]
CBLIF OTNE20WU Strong Biomarker [529]
CCL19 OTQ2UJMH Strong Altered Expression [123]
CCN3 OTOW5YL4 Strong Altered Expression [530]
CCN5 OTADU8JJ Strong Biomarker [531]
CCS OTXHT3QO Strong Genetic Variation [532]
CDH15 OTJ1TO02 Strong Altered Expression [533]
CDK5RAP3 OTC0Q2QS Strong Altered Expression [534]
CDS1 OT2F591M Strong Altered Expression [535]
CDS2 OTKC393S Strong Altered Expression [535]
CELA3B OTGU8BE9 Strong Altered Expression [536]
CENPJ OTZCQZN5 Strong Biomarker [537]
CERS1 OT6EYRM3 Strong Altered Expression [538]
CERS5 OT5A2DNI Strong Altered Expression [538]
CHAMP1 OTBGWU86 Strong Biomarker [539]
CHGB OT7SAQT2 Strong Altered Expression [137]
CIDEA OTDUTSOV Strong Biomarker [79]
CIRBP OTXWTPBL Strong Altered Expression [540]
CLDN10 OT2CVAKY Strong Biomarker [541]
CMPK2 OTOG90R0 Strong Biomarker [436]
CNN1 OTVPG39Z Strong Biomarker [542]
CNOT3 OT4D5Z9L Strong Biomarker [104]
CNPY2 OTGY8ESX Strong Altered Expression [543]
CNTN5 OTWU5FLZ Strong Genetic Variation [544]
COL1A1 OTI31178 Strong Biomarker [545]
COL3A1 OTT1EMLM Strong Altered Expression [51]
CORIN OT4SK7DK Strong Altered Expression [546]
CP OTM8JE4Y Strong Biomarker [324]
CPT1A OTI862QH Strong Biomarker [547]
CPT2 OTIN6G20 Strong Biomarker [547]
CRABP1 OTISDG5X Strong Biomarker [548]
CREBZF OTO3TOEU Strong Biomarker [549]
CREM OTJIJ5AL Strong Biomarker [255]
CRX OTH435SV Strong Biomarker [348]
CRYGC OTYSTQWI Strong Biomarker [550]
CSRP3 OTECBJMV Strong Biomarker [551]
CTCF OT8ZB70U Strong Altered Expression [456]
CTNNA1 OTFC725Z Strong Biomarker [552]
CTRL OTB6NA5O Strong Altered Expression [553]
CTTN OTJRG4ES Strong Biomarker [283]
CYTL1 OTLYUPUY Strong Biomarker [554]
DACT1 OT19Z704 Strong Biomarker [555]
DAPK2 OTWODUQG Strong Biomarker [76]
DBP OTE0W7LN Strong Altered Expression [556]
DCAF6 OT3EYK1J Strong Biomarker [557]
DCD OTV5PBGJ Strong Biomarker [558]
DDAH2 OT8Q40G2 Strong Biomarker [438]
DDT OTF5HTYL Strong Altered Expression [559]
DENR OTXP9HOY Strong Biomarker [76]
DGLUCY OTZD17IM Strong Altered Expression [560]
DHRS7C OTVU4R2D Strong Altered Expression [561]
DLD OT378CU9 Strong Biomarker [562]
DNAAF1 OTYLQLHO Strong Biomarker [563]
DNER OT2GH2E5 Strong Biomarker [564]
DNM1L OTXK1Q1G Strong Altered Expression [565]
DPP3 OTUIVL1C Strong Biomarker [566]
DSG2 OTJPB2TO Strong Genetic Variation [567]
DSP OTB2MOP8 Strong Genetic Variation [568]
DUOX1 OTQ2AEW0 Strong Altered Expression [283]
DUOX2 OTU14HCN Strong Altered Expression [283]
DUSP2 OTH54FMR Strong Biomarker [82]
DYNLL1 OTR69LHT Strong Altered Expression [569]
E2F6 OT2PN28R Strong Biomarker [508]
ECD OT3L3PCU Strong Biomarker [374]
EHD2 OTTX391J Strong Biomarker [171]
EHD3 OTOKC2G5 Strong Biomarker [570]
EIF3K OTGTKVGO Strong Biomarker [571]
ELAVL2 OT6EJ8MQ Strong Biomarker [572]
ELOVL6 OTB26UJJ Strong Biomarker [79]
EMB OT67E3Q1 Strong Biomarker [573]
EMC10 OTQ6S50X Strong Biomarker [574]
EMD OTR8ZANE Strong Biomarker [575]
ENHO OT91QASK Strong Biomarker [576]
ERBIN OTNWTUA8 Strong Biomarker [577]
ERCC6 OT2QZKSF Strong Biomarker [578]
ETV3 OTEN03BM Strong Genetic Variation [579]
EVA1A OTCY3Q2M Strong Biomarker [580]
FAM20C OTW5YZ7X Strong Biomarker [581]
FAM53B OTVD7OU6 Strong Biomarker [582]
FASTK OTTHFZMP Strong Altered Expression [583]
FBL OTRODIE5 Strong Biomarker [584]
FBLN1 OT5MHHOP Strong Altered Expression [585]
FBLN5 OTLVNZ8U Strong Biomarker [586]
FERMT2 OTZNPWWX Strong Biomarker [587]
FHAD1 OT4D6XH0 Strong Altered Expression [588]
FIP1L1 OTF91GTL Strong Biomarker [314]
FKRP OTMUZ7GH Strong Genetic Variation [589]
FKTN OTQ9GCXL Strong Biomarker [590]
FMOD OT9EJ5H8 Strong Altered Expression [591]
FRMD4B OTVI6YFP Strong Genetic Variation [592]
FRY OT74IAG2 Strong Altered Expression [593]
FRZB OTTO3DPY Strong Altered Expression [594]
FSTL1 OT6KEZUD Strong Biomarker [595]
FUNDC1 OTA6IVKQ Strong Altered Expression [596]
FXYD1 OTNKT6GP Strong Biomarker [597]
FZD4 OTGLZIE0 Strong Biomarker [209]
GAB1 OTQKE6V4 Strong Genetic Variation [598]
GABBR1 OTU5A52J Strong Altered Expression [599]
GAL3ST1 OTSFFZRD Strong Biomarker [425]
GALNT1 OTO3RO36 Strong Biomarker [600]
GATM OTIJ4Z11 Strong Altered Expression [601]
GDF11 OTOSNMND Strong Biomarker [602]
GGTLC1 OTWJKUHQ Strong Altered Expression [603]
GIT1 OTHO92S5 Strong Altered Expression [144]
GNA12 OT3IRZH3 Strong Biomarker [77]
GNB3 OTA6HYBA Strong Genetic Variation [604]
GNL2 OTURD1GV Strong Genetic Variation [605]
GNLY OTZJKA8C Strong Biomarker [606]
GNPTAB OT2Z03OB Strong Biomarker [607]
GOLGB1 OT2S0GK8 Strong Biomarker [608]
GPD1L OTVLWW9T Strong Biomarker [609]
GPR151 OT7EACU6 Strong Biomarker [209]
GPX4 OTRAFFX2 Strong Biomarker [333]
GRAP2 OTS5NIZ3 Strong Altered Expression [42]
GTPBP3 OTU52TXX Strong Genetic Variation [610]
GUCA2A OTUSF75G Strong Biomarker [611]
GUCA2B OTZERX04 Strong Biomarker [612]
HADH OTJDOL20 Strong Altered Expression [613]
HADHA OTO557N2 Strong Biomarker [535]
HAND1 OTN4IPVV Strong Genetic Variation [614]
HAND2 OTCXYW4Y Strong Biomarker [346]
HDLBP OTKDEEYX Strong Biomarker [506]
HEBP1 OTR9MPDX Strong Biomarker [506]
HFE OTDD93KB Strong Biomarker [615]
HGS OTCYYCAC Strong Biomarker [616]
HIPK3 OT4WYQM2 Strong Biomarker [617]
HLA-C OTV38BUJ Strong Biomarker [366]
HNRNPD OT5UO1FA Strong Biomarker [618]
HOPX OTBSR6C9 Strong Altered Expression [619]
HOXD10 OT0NOWU2 Strong Altered Expression [599]
HSF2 OTXNJIJ9 Strong Biomarker [620]
HSPA4 OT5HR0AR Strong Altered Expression [621]
HSPB7 OTLATAOV Strong Biomarker [622]
IKBKG OTNWJWSD Strong Altered Expression [623]
IL17RA OTVVI8ER Strong Genetic Variation [624]
IL18BP OTW0LRYZ Strong Biomarker [625]
IL34 OTZ15VVK Strong Altered Expression [626]
IL6R OTCQL07Z Strong Biomarker [627]
ILF3 OTKMZ5K5 Strong Biomarker [628]
IMPACT OTQ923OB Strong Biomarker [629]
INSL6 OTF8OJQC Strong Biomarker [630]
INSRR OT3F75WA Strong Biomarker [631]
ISYNA1 OT49ONSE Strong Altered Expression [286]
ITGA2B OT4Y17PY Strong Biomarker [632]
ITGB1BP2 OTHYX9F3 Strong Genetic Variation [633]
JAML OTOJHNEV Strong Biomarker [634]
JARID2 OT14UM8H Strong Altered Expression [635]
JDP2 OTW35WKX Strong Biomarker [636]
JPH2 OTL9YH7V Strong Biomarker [637]
KAT8 OT5LPQTR Strong Biomarker [638]
KCNE1 OTZNQUW9 Strong Genetic Variation [639]
KCNE2 OTUO214Y Strong Biomarker [640]
KCNIP2 OTY4BLOJ Strong Altered Expression [641]
KCNIP3 OTCQPEM4 Strong Biomarker [642]
KCNK13 OTMOT2KX Strong Altered Expression [643]
KCP OTIS86DZ Strong Biomarker [644]
KLF13 OTMIKHZ4 Strong Biomarker [645]
KLF14 OT8BXLBS Strong Biomarker [646]
KLF15 OTGMQMVR Strong Biomarker [647]
KLF2 OTIP1UFX Strong Altered Expression [648]
KMT2B OTMMAZQX Strong Biomarker [649]
LAD1 OT6YGTVX Strong Biomarker [562]
LGALS13 OTEV3DD7 Strong Biomarker [650]
LGR6 OTPZ1PWR Strong Biomarker [209]
LIAS OTOSW67J Strong Biomarker [651]
LMOD2 OTFXHQFL Strong Biomarker [652]
LRIT1 OTNEQPMZ Strong Biomarker [304]
LRPPRC OTXSK5LP Strong Biomarker [653]
LTBP2 OTS88GSD Strong Altered Expression [654]
LTBP3 OTME98V7 Strong Altered Expression [655]
LUC7L3 OTKDED8A Strong Biomarker [656]
LUM OTSRC874 Strong Altered Expression [657]
LY6G6C OTV7F59X Strong Biomarker [658]
LYST OTIUB1B3 Strong Genetic Variation [659]
MAK16 OTD546E5 Strong Genetic Variation [660]
MAP2K3 OTI2OREX Strong Biomarker [605]
MAP3K12 OT5HODDD Strong Biomarker [271]
MAP3K13 OTS93BTX Strong Biomarker [271]
MAP3K7CL OT9J7RLC Strong Genetic Variation [453]
MAP4K5 OTUFGLXE Strong Biomarker [605]
MAP6 OTPUI00F Strong Biomarker [661]
MARCHF1 OTI2EYO6 Strong Biomarker [662]
MARCHF6 OTBTA03N Strong Biomarker [663]
MARCKSL1 OT13J2FM Strong Biomarker [415]
MATN1 OTBRTCTQ Strong Biomarker [664]
MB OTYWYL2D Strong Biomarker [665]
MCIDAS OTK1JVAH Strong Biomarker [666]
MCU OTQZAYWQ Strong Biomarker [667]
MDFIC OTSRYBWZ Strong Biomarker [668]
MDH2 OT7364GY Strong Biomarker [669]
MED23 OTKZQT0R Strong Biomarker [78]
MEF2C OTZGF1Y5 Strong Altered Expression [670]
MEOX1 OTJEMT2D Strong Altered Expression [671]
METTL3 OTSXP1M3 Strong Biomarker [672]
MFAP1 OTZN4FT3 Strong Biomarker [434]
MFN1 OTCBXQZF Strong Altered Expression [673]
MFN2 OTPYN8A3 Strong Altered Expression [674]
MGP OTZWU3FU Strong Biomarker [675]
MIP OTEBLU3E Strong Altered Expression [676]
MLC1 OTCNZLSP Strong Biomarker [677]
MLEC OTOPGRF5 Strong Genetic Variation [374]
MLIP OTMT7AII Strong Genetic Variation [484]
MLKL OTDSLC81 Strong Altered Expression [678]
MMP28 OTHQZXM1 Strong Altered Expression [679]
MMUT OTBBBV70 Strong Genetic Variation [680]
MOCOS OT0TL3Q5 Strong Biomarker [681]
MOK OTQK7M9V Strong Biomarker [682]
MON2 OTCSVMAR Strong Biomarker [683]
MOV10L1 OTP978LK Strong Biomarker [539]
MPI OTBH6ZK1 Strong Genetic Variation [684]
MPRIP OT5FV5NS Strong Genetic Variation [685]
MRGPRF OT74OZ2Z Strong Biomarker [90]
MRGPRX3 OTRKCCDS Strong Biomarker [209]
MRGPRX4 OTOBHZVA Strong Biomarker [209]
MST1 OTOC4UNG Strong Biomarker [686]
MSX2 OT1WDKE1 Strong Genetic Variation [687]
MTG1 OTC9U1LI Strong Biomarker [688]
MTO1 OT7HCZ1D Strong Genetic Variation [610]
MUC2 OT3X4QVX Strong Biomarker [415]
MYF6 OTLLMHMI Strong Biomarker [689]
MYH14 OT1TZEJK Strong Altered Expression [690]
MYH6 OT3YNCH1 Strong Biomarker [691]
MYL2 OT78PC0C Strong Biomarker [692]
MYL3 OTKD3RSX Strong Genetic Variation [693]
MYL4 OTURFCSE Strong Altered Expression [694]
MYL7 OT7ZNDP4 Strong Biomarker [635]
MYLK3 OTC58V2Q Strong Genetic Variation [695]
MYOC OT6DAHNF Strong Biomarker [696]
MYOCD OTSJNHTH Strong Altered Expression [697]
MYOM3 OT8GGH11 Strong Posttranslational Modification [124]
NAE1 OTMC6F3Y Strong Biomarker [698]
NANOS2 OTFM2IDJ Strong Altered Expression [699]
NANS OTMQ2FUH Strong Genetic Variation [700]
NBAS OTW9IBRI Strong Genetic Variation [281]
NDUFAB1 OTF906UR Strong Biomarker [701]
NEDD4L OT1B19RU Strong Biomarker [702]
NFATC2 OTK5T6HZ Strong Biomarker [703]
NFATC4 OTTDCUAO Strong Altered Expression [704]
NFE2L1 OT1QHOS2 Strong Biomarker [628]
NFIL3 OTQH9HM3 Strong Biomarker [705]
NHS OTKE8QAT Strong Genetic Variation [706]
NLK OT2LETFS Strong Biomarker [707]
NLN OTFRITPU Strong Altered Expression [708]
NLRP6 OTEREN4W Strong Biomarker [709]
NME3 OT0CA0GF Strong Altered Expression [710]
NOS1AP OTDFOBRU Strong Genetic Variation [711]
NOX1 OTZPJQCC Strong Biomarker [333]
NOX3 OT0FFJH8 Strong Altered Expression [712]
NPL OTA7P0TO Strong Biomarker [713]
NPPA OTMQNTNX Strong Biomarker [714]
NR2E3 OTO3GBHQ Strong Biomarker [206]
NRBP2 OTJSTU62 Strong Biomarker [523]
NRF1 OTOXWNV8 Strong Biomarker [628]
NRIP1 OTIZOJQV Strong Biomarker [715]
NSD2 OTQ6SW4R Strong Biomarker [716]
NUP85 OTB5ZHC8 Strong Biomarker [717]
OGA OT7ZBWT1 Strong Altered Expression [718]
OGN OTKP5S4L Strong Biomarker [719]
OMA1 OT0JRVY7 Strong Biomarker [720]
OPN1MW OTPJ7LX4 Strong Biomarker [608]
OPN4 OT1LZ7TS Strong Altered Expression [708]
OPTC OTCASGO0 Strong Genetic Variation [197]
ORAI3 OTUP3OH3 Strong Posttranslational Modification [721]
ORM1 OTZKSBRE Strong Biomarker [423]
OSBP2 OTDGLB4J Strong Biomarker [722]
OSTN OTL4A57N Strong Biomarker [723]
P2RX2 OT0LF34A Strong Altered Expression [301]
P2RX5 OTLBR20R Strong Altered Expression [301]
P2RX6 OT1FNTXA Strong Altered Expression [301]
PAFAH1B1 OT9T2TCJ Strong Biomarker [355]
PAPPA OTTTG9PG Strong Genetic Variation [724]
PCGF2 OTIY1J5L Strong Biomarker [620]
PCMT1 OTGYVSGU Strong Biomarker [725]
PDC OT1UUVYY Strong Biomarker [726]
PDK4 OTCMHMBZ Strong Biomarker [727]
PDS5A OT34P56Z Strong Biomarker [728]
PDS5B OT3U3X8Z Strong Genetic Variation [728]
PDSS2 OTEOQBMX Strong Biomarker [729]
PENK OT8P3HMP Strong Altered Expression [730]
PFN1 OTHTGA1H Strong Biomarker [731]
PGK1 OT6V1ICH Strong Biomarker [732]
PHLDA3 OTXFUDO2 Strong Biomarker [733]
PICK1 OT8QE6EU Strong Biomarker [734]
PIEZO1 OTBG1FU4 Strong Altered Expression [735]
PIF1 OTUHKKVP Strong Biomarker [558]
PIGF OTJKE6VW Strong Biomarker [319]
PINK1 OT50NR57 Strong Biomarker [736]
PITX1 OTA0UN4C Strong Biomarker [90]
PITX3 OTE2KT8P Strong Biomarker [737]
PKD1 OT5ALRZ5 Strong Biomarker [738]
PKD2 OTIXBU8H Strong Genetic Variation [739]
PKHD1 OTAH8SMF Strong Biomarker [740]
PKP2 OTJOVF68 Strong Genetic Variation [741]
PLA2G15 OT6VJTPA Strong Biomarker [432]
PLEKHO1 OTMVUQ9W Strong Genetic Variation [742]
PLIN5 OTV8G50L Strong Biomarker [743]
PLPP3 OTSSF7BK Strong Altered Expression [744]
PLSCR4 OT2AMYLY Strong Biomarker [745]
PNO1 OT010GIS Strong Genetic Variation [660]
PNPLA2 OTR3ERMR Strong Biomarker [746]
POFUT1 OTOBJZIT Strong Altered Expression [747]
POLDIP2 OT8SZSJ6 Strong Altered Expression [42]
POLR2A OTHJQ1DZ Strong Altered Expression [732]
PPA1 OTHZK1QB Strong Altered Expression [292]
PPARGC1A OTHCDQ22 Strong Biomarker [748]
PPBP OT1FHGQS Strong Genetic Variation [749]
PPIG OTZ8BTTM Strong Biomarker [750]
PPM1K OTNZ4N4E Strong Biomarker [751]
PPP1CB OTYFTYFR Strong Altered Expression [752]
PPP1CC OTRZO26U Strong Altered Expression [752]
PPP1R12A OT4AVU95 Strong Altered Expression [690]
PPP1R18 OT0JVGOZ Strong Biomarker [752]
PPP1R1A OTGTAGCV Strong Altered Expression [122]
PPP1R3A OTJL9VYP Strong Biomarker [753]
PPP1R7 OTY5IE69 Strong Biomarker [752]
PPP2R1A OTYA3GB4 Strong Altered Expression [754]
PRDM16 OT0BGA27 Strong Biomarker [398]
PRIMA1 OT9ITT3P Strong Biomarker [755]
PRKAA1 OT7TNF0L Strong Biomarker [756]
PRKAA2 OTU1KZPV Strong Biomarker [756]
PRKAB1 OT1OG4QZ Strong Biomarker [756]
PRKAG2 OTHTAM54 Strong Genetic Variation [757]
PRRT2 OTCJUBDO Strong Altered Expression [72]
PSMG1 OTZ5I6UM Strong Biomarker [82]
PTPA OTRGFOI7 Strong Altered Expression [754]
PTX3 OTPXHRKU Strong Biomarker [737]
PURB OTCDDKYB Strong Altered Expression [758]
QRSL1 OTJDU2UG Strong Genetic Variation [759]
RAB1A OTKPHRD0 Strong Altered Expression [760]
RAC2 OTAOHFNH Strong Genetic Variation [761]
RAPGEF5 OT53VS75 Strong Biomarker [762]
RARRES2 OT1BJE8K Strong Biomarker [763]
RASA4 OTW0178L Strong Biomarker [764]
RBFOX2 OTXY1WVH Strong Biomarker [637]
RBM10 OTES2MES Strong Altered Expression [765]
RBM20 OTOQZNKS Strong Biomarker [766]
RBM24 OTQI1AR1 Strong Biomarker [767]
RBM25 OTVOUOAG Strong Biomarker [768]
RBMS3 OTFSC9MR Strong Genetic Variation [660]
RBP2 OTR8QG5V Strong Altered Expression [769]
REEP5 OTZU4TJI Strong Biomarker [770]
RETN OTW5Z1NH Strong Altered Expression [771]
RHOD OTALMEIN Strong Altered Expression [772]
RHOU OTERIAD4 Strong Altered Expression [773]
RIPK3 OTL1D484 Strong Genetic Variation [685]
RMC1 OT7K8MTJ Strong Biomarker [774]
RMDN1 OTE1NB6U Strong Biomarker [775]
RMDN2 OTK5WSFI Strong Biomarker [775]
RMDN3 OTKO7AUM Strong Biomarker [775]
RND3 OTXMXPIH Strong Biomarker [776]
RNF111 OTO3QT6Q Strong Altered Expression [777]
RNF19A OTKWCV80 Strong Altered Expression [42]
RPGRIP1L OT6Z069I Strong Genetic Variation [133]
RPL32 OTKRQJT4 Strong Biomarker [732]
RRAD OTW2O4GD Strong Altered Expression [778]
RYR2 OT0PF19E Strong Biomarker [393]
RYR3 OT4EHIP4 Strong Biomarker [779]
SAV1 OTSAEV92 Strong Altered Expression [769]
SCARA3 OT46I38Y Strong Biomarker [780]
SCARB2 OTN929M8 Strong Biomarker [781]
SCG2 OTXWUQQL Strong Biomarker [782]
SCGN OTGD7SKH Strong Biomarker [783]
SCN7A OTK05PXY Strong Genetic Variation [281]
SDC4 OTKUVUGZ Strong Biomarker [784]
SDCBP2 OT1AT2OL Strong Biomarker [447]
SERPINA5 OTTZXPGD Strong Biomarker [785]
SFTPB OTOHS07E Strong Biomarker [786]
SGTA OTKOJ3JB Strong Biomarker [374]
SLBP OTVYYQRT Strong Biomarker [506]
SLMAP OTHW3DVC Strong Biomarker [787]
SLN OTERIU75 Strong Altered Expression [788]
SLPI OTUNFUU8 Strong Altered Expression [81]
SLU7 OTZUUICN Strong Altered Expression [768]
SMCP OTXKY794 Strong Biomarker [681]
SMYD1 OTPAH75C Strong Genetic Variation [789]
SOD3 OTIOZQAB Strong Genetic Variation [790]
SPEG OTQXWJR4 Strong Biomarker [680]
SPON1 OTC06MY4 Strong Biomarker [195]
SPRR2B OTQ9WPKY Strong Biomarker [791]
SPTAN1 OT6VY3A3 Strong Biomarker [792]
SRF OTW18FQN Strong Biomarker [793]
SRI OT4R3EAC Strong Biomarker [794]
SRRM2 OTSIMMC9 Strong Genetic Variation [660]
SSB OTCCTPBR Strong Genetic Variation [795]
STAM2 OT9OBWPH Strong Biomarker [506]
STIM1 OT8CLQ1W Strong Biomarker [796]
STRN OTLOZL5I Strong Biomarker [797]
STUB1 OTSUYI9A Strong Biomarker [798]
SUCLA2 OTMZD4PW Strong Biomarker [799]
SUCO OT3I9VO9 Strong Genetic Variation [197]
SUMO1 OTJFD4P5 Strong Altered Expression [800]
SUMO2 OT1Y5IKN Strong Biomarker [801]
SUMO3 OTTUJQJ1 Strong Biomarker [802]
SYBU OT3FQV7N Strong Biomarker [775]
SYCP3 OTKOF54H Strong Biomarker [803]
SYPL2 OT6CV0CA Strong Biomarker [804]
TCFL5 OTJL4348 Strong Biomarker [805]
TCHP OTVDMHSY Strong Biomarker [806]
TEAD1 OTK6971C Strong Altered Expression [299]
TET2 OTKKT03T Strong Genetic Variation [798]
TFAM OTXXV5V7 Strong Biomarker [807]
TFEB OTJUJJQY Strong Genetic Variation [808]
TFR2 OTMYCCEO Strong Genetic Variation [809]
TGS1 OTM79LML Strong Biomarker [725]
TIMELESS OTD8DCBJ Strong Biomarker [462]
TIMM50 OTWJNUQL Strong Biomarker [810]
TIMM8A OTDX9687 Strong Genetic Variation [811]
TIMP4 OT8A68SW Strong Altered Expression [812]
TLX2 OTPFAUM8 Strong Biomarker [813]
TMBIM1 OTE47B57 Strong Altered Expression [814]
TMEM109 OTLUUDH1 Strong Altered Expression [815]
TMTC3 OTMTTDYG Strong Biomarker [549]
TOR1AIP1 OTTG8MAK Strong Biomarker [816]
TPI1 OT14KP4B Strong Biomarker [462]
TPM1 OTD73X6R Strong Genetic Variation [817]
TRAF2 OT1MEZZN Strong Genetic Variation [818]
TRDN OTXVE9SF Strong Genetic Variation [459]
TRIM32 OTJOV0PG Strong Biomarker [819]
TRIM55 OTY5YQFX Strong Biomarker [820]
TRIM72 OTFAFXPC Strong Biomarker [171]
TSPAN31 OT8WQ83R Strong Genetic Variation [700]
ACAN OTUOCW8K Definitive Biomarker [821]
BAG3 OTVXYUDQ Definitive Biomarker [822]
CASP12 OTY2W6FG Definitive Therapeutic [823]
ENDOG OT5IM7B3 Definitive Biomarker [824]
FKBP1B OT8CMPB2 Definitive Biomarker [825]
GRK1 OT7MPSG7 Definitive Biomarker [826]
LMNA OT3SG7ZR Definitive Genetic Variation [827]
MYOD1 OTV2S79X Definitive Therapeutic [828]
NPTXR OTQJEOIH Definitive Biomarker [164]
OGT OT1Z1ZXE Definitive Biomarker [829]
PLCD1 OT6WFVXZ Definitive Biomarker [830]
RAMP2 OTGQXLH5 Definitive Biomarker [831]
RNLS OTVP2WJM Definitive Biomarker [832]
TOMM70 OT8QBYZ0 Definitive Biomarker [833]
TTN OT0LZ058 Definitive Biomarker [834]
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References

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75 Emerging role of SIRT3 in mitochondrial dysfunction and cardiovascular diseases.Free Radic Res. 2019 Feb;53(2):139-149. doi: 10.1080/10715762.2018.1549732. Epub 2018 Dec 26.
76 The mechanical effects of CRT promoting autophagy via mitochondrial calcium uniporter down-regulation and mitochondrial dynamics alteration.J Cell Mol Med. 2019 Jun;23(6):3833-3842. doi: 10.1111/jcmm.14227. Epub 2019 Apr 2.
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78 Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts.J Mol Cell Cardiol. 2011 Aug;51(2):215-25. doi: 10.1016/j.yjmcc.2011.04.016. Epub 2011 May 7.
79 Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. J Biol Chem. 2016 Feb 5;291(6):2583-600. doi: 10.1074/jbc.M115.702688. Epub 2015 Dec 15.
80 Albuminuria as a Predictor of Cardiovascular Outcomes in Patients With Acute Myocardial Infarction.J Am Heart Assoc. 2019 Apr 16;8(8):e010546. doi: 10.1161/JAHA.118.010546.
81 Reduced activin receptor-like kinase 1 activity promotes cardiac fibrosis in heart failure.Cardiovasc Pathol. 2017 Nov-Dec;31:26-33. doi: 10.1016/j.carpath.2017.07.004. Epub 2017 Jul 18.
82 Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptor 1 (PAC1) in the human infant brain and changes in the Sudden Infant Death Syndrome (SIDS).Neurobiol Dis. 2017 Jul;103:70-77. doi: 10.1016/j.nbd.2017.04.002. Epub 2017 Apr 6.
83 Biomarkers of Inflammation, Fibrosis, and Acute Kidney Injury in Patients with Heart Failure with and without Left Ventricular Assist Device Implantation.Cardiorenal Med. 2019;9(2):108-116. doi: 10.1159/000494090. Epub 2019 Jan 30.
84 Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failure.Mol Med Rep. 2017 Aug;16(2):1723-1730. doi: 10.3892/mmr.2017.6776. Epub 2017 Jun 14.
85 Rationale and design of the phase 2b clinical trials to study the effects of the partial adenosine A1-receptor agonist neladenoson bialanate in patients with chronic heart failure with reduced (PANTHEON) and preserved (PANACHE) ejection fraction.Eur J Heart Fail. 2018 Nov;20(11):1601-1610. doi: 10.1002/ejhf.1295. Epub 2018 Sep 17.
86 The association of ADORA2A and ADORA2B polymorphisms with the risk and severity of chronic heart failure: a case-control study of a northern Chinese population.Int J Mol Sci. 2015 Jan 26;16(2):2732-46. doi: 10.3390/ijms16022732.
87 Cardioprotective role of APIP in myocardial infarction through ADORA2B.Cell Death Dis. 2019 Jul 1;10(7):511. doi: 10.1038/s41419-019-1746-3.
88 The Polymorphism in ADORA3 Decreases Transcriptional Activity and Influences the Chronic Heart Failure Risk in the Chinese.Biomed Res Int. 2018 May 31;2018:4969385. doi: 10.1155/2018/4969385. eCollection 2018.
89 The first-in-man randomized trial of a beta3 adrenoceptor agonist in chronic heart failure: the BEAT-HF trial.Eur J Heart Fail. 2017 Apr;19(4):566-575. doi: 10.1002/ejhf.714. Epub 2016 Dec 18.
90 Paediatric deaths in a tertiary government hospital setting, Malawi.Paediatr Int Child Health. 2019 Nov;39(4):240-248. doi: 10.1080/20469047.2018.1536873. Epub 2018 Nov 19.
91 Specifics of fetuin-A levels in distinct types of chronic heart failure.J Clin Lab Anal. 2018 Jan;32(1):e22179. doi: 10.1002/jcla.22179. Epub 2017 Feb 18.
92 Anti-1-Adrenoreceptor auto-Antibodies in elderly heart failure patients.Front Biosci (Landmark Ed). 2019 Mar 1;24(6):1037-1049. doi: 10.2741/4766.
93 Mediators of the Effects of Canagliflozin on HeartFailure in Patients With Type 2 Diabetes.JACC Heart Fail. 2020 Jan;8(1):57-66. doi: 10.1016/j.jchf.2019.08.004. Epub 2019 Oct 29.
94 Acetaldehyde dehydrogenase 2 deficiency exacerbates cardiac fibrosis by promoting mobilization and homing of bone marrow fibroblast progenitor cells.J Mol Cell Cardiol. 2019 Dec;137:107-118. doi: 10.1016/j.yjmcc.2019.10.006. Epub 2019 Oct 24.
95 Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner.PLoS One. 2018 Aug 23;13(8):e0202693. doi: 10.1371/journal.pone.0202693. eCollection 2018.
96 Targeted therapy of underlying conditions improves quality of life in patients with persistent atrial fibrillation: results of the RACE 3 study.Europace. 2019 Apr 1;21(4):563-571. doi: 10.1093/europace/euy311.
97 Sacubitril/Valsartan: Updates and Clinical Evidence for a Disease-Modifying Approach.Drugs. 2019 Sep;79(14):1543-1556. doi: 10.1007/s40265-019-01181-2.
98 Annexin A5 in treated hypertensive patients and its association with target organ damage.J Hypertens. 2017 Jan;35(1):154-161. doi: 10.1097/HJH.0000000000001143.
99 C-reactive protein in heart failure: prognostic value and the effect of valsartan. Circulation. 2005 Sep 6;112(10):1428-34. doi: 10.1161/CIRCULATIONAHA.104.508465. Epub 2005 Aug 29.
100 Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels.J Am Coll Cardiol. 2011 Jan 18;57(3):356-65. doi: 10.1016/j.jacc.2010.08.635.
101 -Arrestin 2 mediates arginine vasopressin-induced IL-6 induction via the ERK(1/2)-NF-B signal pathway in murine hearts.Acta Pharmacol Sin. 2020 Feb;41(2):198-207. doi: 10.1038/s41401-019-0292-y. Epub 2019 Sep 12.
102 Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling.Circulation. 2018 Jun 5;137(23):2497-2513. doi: 10.1161/CIRCULATIONAHA.117.030353. Epub 2018 Jan 25.
103 Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride.Brain. 2013 Jan;136(Pt 1):106-15. doi: 10.1093/brain/aws325.
104 The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.Sci Signal. 2018 Feb 6;11(516):eaan3638. doi: 10.1126/scisignal.aan3638.
105 The influence of post-infarct heart failure and high fat diet on the expression of apelin APJ and vasopressin V1a and V1b receptors.Neuropeptides. 2019 Dec;78:101975. doi: 10.1016/j.npep.2019.101975. Epub 2019 Oct 15.
106 Utilization and budget impact of tolvaptan in the inpatient setting among patients with heart failure and hyponatremia.Curr Med Res Opin. 2018 Mar;34(3):559-566. doi: 10.1080/03007995.2018.1423958. Epub 2018 Jan 22.
107 Axl expression is increased in early stages of left ventricular remodeling in an animal model with pressure-overload.PLoS One. 2019 Jun 10;14(6):e0217926. doi: 10.1371/journal.pone.0217926. eCollection 2019.
108 Increased BACE1-AS long noncoding RNA and -amyloid levels in heart failure.Cardiovasc Res. 2017 Apr 1;113(5):453-463. doi: 10.1093/cvr/cvx013.
109 Serum Levels of Inflammatory Cytokines and Expression of BCL2 and BAX mRNA in Peripheral Blood Mononuclear Cells and in Patients with Chronic Heart Failure.Med Sci Monit. 2019 Apr 10;25:2633-2639. doi: 10.12659/MSM.912457.
110 Global secretome analysis of resident cardiac progenitor cells from wild-type and transgenic heart failure mice: Why ambience matters.J Cell Physiol. 2019 Jul;234(7):10111-10122. doi: 10.1002/jcp.27677. Epub 2018 Dec 21.
111 Shortterm vagus nerve stimulation reduces myocardial apoptosis by downregulating microRNA?05 in rats with chronic heart failure.Mol Med Rep. 2017 Nov;16(5):5847-5854. doi: 10.3892/mmr.2017.7344. Epub 2017 Aug 23.
112 Randomised placebo-controlled safety and tolerability trial of FK506 (tacrolimus) for pulmonary arterial hypertension.Eur Respir J. 2017 Sep 11;50(3):1602449. doi: 10.1183/13993003.02449-2016. Print 2017 Sep.
113 Relationship between the autoantibody and expression of 3-adrenoceptor in lung and heart.PLoS One. 2013 Jul 5;8(7):e68747. doi: 10.1371/journal.pone.0068747. Print 2013.
114 The roles of CyPA and CD147 in cardiac remodelling.Exp Mol Pathol. 2018 Jun;104(3):222-226. doi: 10.1016/j.yexmp.2018.05.001. Epub 2018 May 14.
115 Myocardial expression of the anaphylatoxin receptor C3aR is associated with cardiac inflammation and prognosis in patients with non-ischaemic heart failure.ESC Heart Fail. 2018 Oct;5(5):846-857. doi: 10.1002/ehf2.12298. Epub 2018 Aug 31.
116 Transgenic expression of carbonic anhydrase III in cardiac muscle demonstrates a mechanism to tolerate acidosis.Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C922-C931. doi: 10.1152/ajpcell.00130.2019. Epub 2019 Aug 7.
117 Lipid-Lowering Agents in Older Individuals: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.J Clin Endocrinol Metab. 2019 May 1;104(5):1585-1594. doi: 10.1210/jc.2019-00195.
118 Cessation of pulmonary and coronary secretion of adrenomedullin peptides in the progression of human heart failure.Horm Metab Res. 2002 Feb;34(2):81-6. doi: 10.1055/s-2002-20520.
119 Increased calpain-1 in mitochondria induces dilated heart failure in mice: role of mitochondrial superoxide anion.Basic Res Cardiol. 2019 Mar 15;114(3):17. doi: 10.1007/s00395-019-0726-1.
120 Renal sympathetic denervation improves myocardial apoptosis in rats with isoproterenol-induced heart failure by downregulation of tumor necrosis factor- and nuclear factor-B.Exp Ther Med. 2017 Nov;14(5):4104-4110. doi: 10.3892/etm.2017.5066. Epub 2017 Aug 30.
121 Cardioprotective effect of the secretome of Sca-1+ and Sca-1- cells in heart failure: not equal, but equally important?.Cardiovasc Res. 2020 Mar 1;116(3):566-575. doi: 10.1093/cvr/cvz140.
122 Astragalosides increase the cardiac diastolic function and regulate the "Calcium sensing receptor-protein kinase C-protein phosphatase 1" pathway in rats with heart failure.Biomed Pharmacother. 2018 Jul;103:838-843. doi: 10.1016/j.biopha.2018.04.111. Epub 2018 Apr 24.
123 Homeostatic Chemokines and Prognosisin Patients With Acute Coronary Syndromes.J Am Coll Cardiol. 2019 Aug 13;74(6):774-782. doi: 10.1016/j.jacc.2019.06.030.
124 Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes.Circ Heart Fail. 2019 Mar;12(3):e005765. doi: 10.1161/CIRCHEARTFAILURE.118.005765.
125 Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart.Circ Res. 2019 Mar 15;124(6):881-890. doi: 10.1161/CIRCRESAHA.118.314030.
126 Transendocardial CD34+ Cell Therapy does not Increase the Risk of Ventricular Arrhythmias in Patients with Chronic Heart Failure.Cell Transplant. 2019 Jul;28(7):856-863. doi: 10.1177/0963689719840351. Epub 2019 May 2.
127 Enhancing fatty acid utilization ameliorates mitochondrial fragmentation and cardiac dysfunction via rebalancing optic atrophy 1 processing in the failing heart.Cardiovasc Res. 2018 Jun 1;114(7):979-991. doi: 10.1093/cvr/cvy052.
128 Alpha-receptor blockade improves muscle perfusion and glucose uptake in heart failure.Eur J Heart Fail. 2010 Oct;12(10):1061-6. doi: 10.1093/eurjhf/hfq135. Epub 2010 Aug 5.
129 CD69 limits the severity of cardiomyopathy after autoimmune myocarditis.Circulation. 2010 Oct 5;122(14):1396-404. doi: 10.1161/CIRCULATIONAHA.110.952820. Epub 2010 Sep 20.
130 Increased gene expression of tumor necrosis factor superfamily ligands in peripheral blood mononuclear cells during chronic heart failure.Cardiovasc Res. 2002 Apr;54(1):175-82. doi: 10.1016/s0008-6363(02)00238-9.
131 Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure.JCI Insight. 2017 Aug 3;2(15):e92476. doi: 10.1172/jci.insight.92476. eCollection 2017 Aug 3.
132 TAK-272 (imarikiren), a novel renin inhibitor, improves cardiac remodeling and mortality in a murine heart failure model.PLoS One. 2018 Aug 9;13(8):e0202176. doi: 10.1371/journal.pone.0202176. eCollection 2018.
133 MKS3/TMEM67 mutations are a major cause of COACH Syndrome, a Joubert Syndrome related disorder with liver involvement.Hum Mutat. 2009 Feb;30(2):E432-42. doi: 10.1002/humu.20924.
134 Cholesteryl ester transfer protein (CETP), HDL capacity of receiving cholesterol and status of inflammatory cytokines in patients with severe heart failure.Lipids Health Dis. 2018 Oct 20;17(1):242. doi: 10.1186/s12944-018-0888-0.
135 The alternative complement pathway is dysregulated in patients with chronic heart failure.Sci Rep. 2017 Feb 14;7:42532. doi: 10.1038/srep42532.
136 Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction.Basic Res Cardiol. 2012 Jan;107(1):239. doi: 10.1007/s00395-011-0239-z. Epub 2011 Dec 28.
137 Regulation of circulating chromogranin B levels in heart failure.Biomarkers. 2018 Feb;23(1):78-87. doi: 10.1080/1354750X.2017.1395079. Epub 2017 Nov 7.
138 Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor.Eur J Med Chem. 2018 Sep 5;157:1500-1511. doi: 10.1016/j.ejmech.2018.08.062. Epub 2018 Aug 23.
139 The ClC-3 chloride channels in cardiovascular disease.Acta Pharmacol Sin. 2011 Jun;32(6):675-84. doi: 10.1038/aps.2011.30. Epub 2011 May 23.
140 Loss-of-function DNA sequence variant in the CLCNKA chloride channel implicates the cardio-renal axis in interindividual heart failure risk variation.Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2456-61. doi: 10.1073/pnas.1017494108. Epub 2011 Jan 19.
141 Cardiac natriuretic peptides: from basic discovery to clinical practice.Cardiovasc Ther. 2011 Dec;29(6):362-76. doi: 10.1111/j.1755-5922.2010.00152.x. Epub 2010 Apr 23.
142 Right Ventricular and Pulmonary Vascular Function are Influenced by Age and Volume Expansion in Healthy Humans.J Card Fail. 2019 Jan;25(1):51-59. doi: 10.1016/j.cardfail.2018.11.013. Epub 2018 Nov 22.
143 Astragaloside IV inhibits ventricular remodeling and improves fatty acid utilization in rats with chronic heart failure.Biosci Rep. 2018 May 22;38(3):BSR20171036. doi: 10.1042/BSR20171036. Print 2018 May 29.
144 Reduced myocardial and systemic L-arginine uptake in heart failure.Circ Res. 2002 Dec 13;91(12):1198-203. doi: 10.1161/01.res.0000047506.52381.90.
145 Cardiac CRFR1 Expression Is Elevated in Human Heart Failure and Modulated by Genetic Variation and Alternative Splicing.Endocrinology. 2016 Dec;157(12):4865-4874. doi: 10.1210/en.2016-1448. Epub 2016 Oct 18.
146 Corticotropin-Releasing Hormone Family and Their Receptors in the Cardiovascular System.Circ J. 2019 Jan 25;83(2):261-266. doi: 10.1253/circj.CJ-18-0428. Epub 2018 Dec 22.
147 Chronic interval exercise training prevents BK(Ca) channel-mediated coronary vascular dysfunction in aortic-banded miniswine.J Appl Physiol (1985). 2018 Jul 1;125(1):86-96. doi: 10.1152/japplphysiol.01138.2017. Epub 2018 Mar 29.
148 Psychometric Validation of the Mandarin Version Control Attitudes Scale-Revised Questionnaire in Taiwanese Patients With Heart Failure.J Cardiovasc Nurs. 2018 Mar/Apr;33(2):187-194. doi: 10.1097/JCN.0000000000000431.
149 Combined therapy with cardioprotective cytokine administration and antiapoptotic gene transfer in postinfarction heart failure.Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H616-26. doi: 10.1152/ajpheart.01147.2008. Epub 2009 Jan 16.
150 CT-1 (Cardiotrophin-1)-Gal-3 (Galectin-3) Axis in Cardiac Fibrosis and Inflammation.Hypertension. 2019 Mar;73(3):602-611. doi: 10.1161/HYPERTENSIONAHA.118.11874.
151 Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca(2+)/calmodulin-dependent protein kinase II.Redox Biol. 2018 Oct;19:250-262. doi: 10.1016/j.redox.2018.08.008. Epub 2018 Aug 22.
152 Molecular network, pathway, and functional analysis of time-dependent gene changes related to cathepsin G exposure in neonatal rat cardiomyocytes.Gene. 2018 Sep 10;671:58-66. doi: 10.1016/j.gene.2018.05.110. Epub 2018 May 31.
153 Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.Cell Death Dis. 2018 Jun 7;9(6):692. doi: 10.1038/s41419-018-0727-2.
154 Circulating proteomic signature of early death in heart failure patients with reduced ejection fraction.Sci Rep. 2019 Dec 16;9(1):19202. doi: 10.1038/s41598-019-55727-1.
155 Fractalkine promotes platelet activation and vascular dysfunction in congestive heart failure.Thromb Haemost. 2014 Apr 1;111(4):725-35. doi: 10.1160/TH13-08-0640. Epub 2013 Dec 12.
156 Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.J Toxicol Environ Health A. 2012;75(4):213-31. doi: 10.1080/15287394.2012.652055.
157 Early administration of empagliflozin preserved heart function in cardiorenal syndrome in rat.Biomed Pharmacother. 2019 Jan;109:658-670. doi: 10.1016/j.biopha.2018.10.095. Epub 2018 Nov 4.
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159 CYP2D6 Genetic Variation and Beta-Blocker Maintenance Dose in Patients with Heart Failure.Pharm Res. 2017 Aug;34(8):1615-1625. doi: 10.1007/s11095-017-2104-8. Epub 2017 Feb 8.
160 Endothelium-specific CYP2J2 overexpression improves cardiac dysfunction by promoting angiogenesis via Jagged1/Notch1 signaling.J Mol Cell Cardiol. 2018 Oct;123:118-127. doi: 10.1016/j.yjmcc.2018.08.027. Epub 2018 Sep 13.
161 Impact of CYP3A5 genotype on tolvaptan pharmacokinetics and their relationships with endogenous markers of CYP3A activity and serum sodium level in heart failure patients.Basic Clin Pharmacol Toxicol. 2020 Apr;126(4):353-363. doi: 10.1111/bcpt.13355. Epub 2019 Nov 15.
162 Effects of zamicastat treatment in a genetic model of salt-sensitive hypertension and heart failure.Eur J Pharmacol. 2019 Jan 5;842:125-132. doi: 10.1016/j.ejphar.2018.10.030. Epub 2018 Oct 26.
163 Redd1 protects against postinfarction cardiac dysfunction by targeting apoptosis and autophagy.Int J Mol Med. 2019 Dec;44(6):2065-2076. doi: 10.3892/ijmm.2019.4366. Epub 2019 Oct 4.
164 Regulation of neuronal type genes in congestive heart failure rats.Acta Physiol (Oxf). 2006 Jan;186(1):17-27. doi: 10.1111/j.1748-1716.2005.01503.x.
165 Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure.J Biol Chem. 2014 Oct 24;289(43):29881-91. doi: 10.1074/jbc.M114.601864. Epub 2014 Aug 25.
166 The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy.Cardiovasc Res. 2018 Sep 1;114(11):1474-1486. doi: 10.1093/cvr/cvy091.
167 Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis.Circ Res. 2009 Apr 10;104(7):896-904. doi: 10.1161/CIRCRESAHA.108.172882. Epub 2009 Feb 26.
168 Dynamin-2 mediates heart failure by modulating Ca2+ -dependent cardiomyocyte apoptosis.Int J Cardiol. 2013 Oct 3;168(3):2109-19. doi: 10.1016/j.ijcard.2013.01.006. Epub 2013 Feb 11.
169 DPP10 is a new regulator of Nav1.5 channels in human heart.Int J Cardiol. 2019 Jun 1;284:68-73. doi: 10.1016/j.ijcard.2018.12.072. Epub 2019 Jan 3.
170 Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.Front Physiol. 2018 Nov 14;9:1622. doi: 10.3389/fphys.2018.01622. eCollection 2018.
171 Cardiomyocyte damage control in heart failure and the role of the sarcolemma.J Muscle Res Cell Motil. 2019 Dec;40(3-4):319-333. doi: 10.1007/s10974-019-09539-5. Epub 2019 Sep 13.
172 Endothelin-converting enzyme inhibition in the rat model of acute heart failure: heart function and neurohormonal activation.Exp Biol Med (Maywood). 2009 Oct;234(10):1201-11. doi: 10.3181/0902-RM-62. Epub 2009 Jul 13.
173 Influence of Mechanical Circulatory Support on Endothelin Receptor Expression in Human Left Ventricular Myocardium from Patients with Dilated Cardiomyopathy (DCM).PLoS One. 2017 Jan 17;12(1):e0169896. doi: 10.1371/journal.pone.0169896. eCollection 2017.
174 Plasma Ceramides and Sphingomyelins in Relation to Heart Failure Risk.Circ Heart Fail. 2019 Jul;12(7):e005708. doi: 10.1161/CIRCHEARTFAILURE.118.005708. Epub 2019 Jul 12.
175 Mammalian enabled (Mena) is a critical regulator of cardiac function.Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1841-52. doi: 10.1152/ajpheart.01127.2010. Epub 2011 Feb 18.
176 Bone Morphogenetic Protein 9 Reduces Cardiac Fibrosis and Improves Cardiac Function in Heart Failure.Circulation. 2018 Jul 31;138(5):513-526. doi: 10.1161/CIRCULATIONAHA.117.031635.
177 Specific Inhibition of Brain Angiotensin III Formation as a New Strategy for Prevention of Heart Failure After Myocardial Infarction.J Cardiovasc Pharmacol. 2019 Feb;73(2):82-91. doi: 10.1097/FJC.0000000000000638.
178 Soluble epoxide hydrolase inhibitors and heart failure.Cardiovasc Ther. 2011 Apr;29(2):99-111. doi: 10.1111/j.1755-5922.2010.00150.x.
179 ErbB4 Gene Polymorphism Is Associated With the Risk and Prognosis of Congestive Heart Failure in a Northern Han Chinese Population.J Card Fail. 2016 Sep;22(9):700-9. doi: 10.1016/j.cardfail.2016.01.013. Epub 2016 Feb 1.
180 The serine/threonine-protein kinase/endoribonuclease IRE1 protects the heart against pressure overload-induced heart failure.J Biol Chem. 2018 Jun 22;293(25):9652-9661. doi: 10.1074/jbc.RA118.003448. Epub 2018 May 16.
181 AMP activated protein kinase-2 regulates expression of estrogen-related receptor-, a metabolic transcription factor related to heart failure development.Hypertension. 2011 Oct;58(4):696-703. doi: 10.1161/HYPERTENSIONAHA.111.174128. Epub 2011 Aug 8.
182 Successful COMPASS, Disappointing COMMANDER HF, What Have We Learned From These Two Trials?.J Cardiovasc Pharmacol. 2019 Oct;74(4):306-307. doi: 10.1097/FJC.0000000000000712.
183 Edoxaban suppresses the progression of atrial fibrosis and atrial fibrillation in a canine congestive heart failure model.Heart Vessels. 2019 Aug;34(8):1381-1388. doi: 10.1007/s00380-019-01377-2. Epub 2019 Mar 14.
184 Clinical, respiratory, haemodynamic, and metabolic determinants of lactate in heart failure.Kardiol Pol. 2019;77(1):47-52. doi: 10.5603/KP.a2018.0240. Epub 2018 Dec 19.
185 Influences of Ivabradine treatment on serum levels of cardiac biomarkers sST2, GDF-15, suPAR and H-FABP in patients with chronic heart failure.Acta Pharmacol Sin. 2018 Jul;39(7):1189-1196. doi: 10.1038/aps.2017.167. Epub 2017 Dec 14.
186 Cardiometabolic Biomarkers and Their Temporal Patterns Predict Poor Outcome in Chronic Heart Failure (Bio-SHiFT Study).J Clin Endocrinol Metab. 2018 Nov 1;103(11):3954-3964. doi: 10.1210/jc.2018-01241.
187 Shenfu Formula reduces cardiomyocyte apoptosis in heart failure rats by regulating microRNAs.J Ethnopharmacol. 2018 Dec 5;227:105-112. doi: 10.1016/j.jep.2018.05.006. Epub 2018 May 8.
188 Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in mice.Cardiovasc Res. 2013 Mar 1;97(3):490-9. doi: 10.1093/cvr/cvs347. Epub 2012 Nov 24.
189 3-Polyunsaturated fatty acids for heart failure: Effects of dose on efficacy and novel signaling through free fatty acid receptor 4.J Mol Cell Cardiol. 2017 Feb;103:74-92. doi: 10.1016/j.yjmcc.2016.12.003. Epub 2016 Dec 14.
190 FGF-4 gene therapy GENERX--Collateral Therapeutics.BioDrugs. 2002;16(1):75-6. doi: 10.2165/00063030-200216010-00010.
191 Fibroblast Growth Factor 23 Genotype and Cardiovascular Disease in Patients Undergoing Hemodialysis.Am J Nephrol. 2019;49(2):125-132. doi: 10.1159/000496060. Epub 2019 Jan 22.
192 Ryanodine receptors, FKBP12, and heart failure.Front Biosci. 2002 Apr 1;7:d970-7. doi: 10.2741/A822.
193 Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence.Sci Signal. 2018 Nov 13;11(556):eaat5185. doi: 10.1126/scisignal.aat5185.
194 Cardiac gene expression profile in rats with terminal heart failure and cachexia.Physiol Genomics. 2005 Feb 10;20(3):256-67. doi: 10.1152/physiolgenomics.00165.2004. Epub 2004 Dec 28.
195 Circulating proteins as predictors of incident heart failure in the elderly.Eur J Heart Fail. 2018 Jan;20(1):55-62. doi: 10.1002/ejhf.980. Epub 2017 Oct 2.
196 Activin type II receptor signaling in cardiac aging and heart failure.Sci Transl Med. 2019 Mar 6;11(482):eaau8680. doi: 10.1126/scitranslmed.aau8680.
197 Optimising pacemaker therapy and medical therapy in pacemaker patients for heart failure: protocol for the OPT-PACE randomised controlled trial.BMJ Open. 2019 Jul 17;9(7):e028613. doi: 10.1136/bmjopen-2018-028613.
198 c-Jun N-terminal Kinase mediates prostaglandin-induced sympathoexcitation in rats with chronic heart failure by reducing GAD1 and GABRA1 expression.Acta Physiol (Oxf). 2017 Feb;219(2):494-509. doi: 10.1111/apha.12758. Epub 2016 Aug 12.
199 Role of sympathetic cotransmitter galanin on autonomic balance in heart failure: an active player or a bystander?.Anatol J Cardiol. 2017 Oct;18(4):281-288. doi: 10.14744/AnatolJCardiol.2017.7831. Epub 2017 Aug 11.
200 Serum levels of Growth Arrest-Specific 6 protein and soluble AXL in patients with ST-segment elevation myocardial infarction.Eur Heart J Acute Cardiovasc Care. 2019 Dec;8(8):708-716. doi: 10.1177/2048872617740833. Epub 2017 Nov 9.
201 Exercise training augments neuronal nitric oxide synthase dimerization in the paraventricular nucleus of rats with chronic heart failure.Nitric Oxide. 2019 Jun 1;87:73-82. doi: 10.1016/j.niox.2019.03.005. Epub 2019 Mar 13.
202 Mechanisms of Ghrelin anti-heart failure: inhibition of Ang II-induced cardiomyocyte apoptosis by down-regulating AT1R expression.PLoS One. 2014 Jan 21;9(1):e85785. doi: 10.1371/journal.pone.0085785. eCollection 2014.
203 Immuno-Spin Trapping-Based Detection of Oxidative Modifications in Cardiomyocytes and Coronary Endothelium in the Progression of Heart Failure in Tgq*44 Mice.Front Immunol. 2018 May 7;9:938. doi: 10.3389/fimmu.2018.00938. eCollection 2018.
204 Association of Oxidative Stress and Platelet Receptor Glycoprotein GPIb and GPVI Shedding During Nonsurgical Bleeding in Heart Failure Patients With Continuous-Flow Left Ventricular Assist Device Support.ASAIO J. 2018 Jul/Aug;64(4):462-471. doi: 10.1097/MAT.0000000000000680.
205 TGR5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure-induced stress in mice.Cardiovasc Ther. 2018 Oct;36(5):e12462. doi: 10.1111/1755-5922.12462. Epub 2018 Aug 22.
206 Ribonucleotide reductase-mediated increase in dATP improves cardiac performance via myosin activation in a large animal model of heart failure.Eur J Heart Fail. 2015 Aug;17(8):772-81. doi: 10.1002/ejhf.270. Epub 2015 Apr 15.
207 Resolution of inflammation is altered in chronic heart failure and entails a dysfunctional responsiveness of T lymphocytes.FASEB J. 2019 Jan;33(1):909-916. doi: 10.1096/fj.201801017R. Epub 2018 Jul 27.
208 The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice.Am J Hypertens. 2018 Aug 3;31(9):1049-1058. doi: 10.1093/ajh/hpy073.
209 GRK2 as a therapeutic target for heart failure.Expert Opin Ther Targets. 2018 Jan;22(1):75-83. doi: 10.1080/14728222.2018.1406925. Epub 2017 Nov 23.
210 Effect of the changes of NMDA receptor in hypothalamic paraventricular nucleus on cardiac function and sympathetic nervous activity in rats with heart failure.Biochem Biophys Res Commun. 2017 Nov 25;493(3):1336-1341. doi: 10.1016/j.bbrc.2017.09.140. Epub 2017 Sep 27.
211 Changes in Adrenoceptor and GRK Expression in Patients With Chronic Pulmonary Regurgitation.Rev Esp Cardiol (Engl Ed). 2019 Jul;72(7):569-576. doi: 10.1016/j.rec.2018.05.030. Epub 2018 Aug 10.
212 Cardiomyocyte-GSK-3 promotes mPTP opening and heart failure in mice with chronic pressure overload.J Mol Cell Cardiol. 2019 May;130:65-75. doi: 10.1016/j.yjmcc.2019.03.020. Epub 2019 Mar 27.
213 Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3 Function Independent of Its Phosphorylation State.Circ Res. 2018 May 25;122(11):1517-1531. doi: 10.1161/CIRCRESAHA.118.312789. Epub 2018 Mar 21.
214 PI3K-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.Nat Commun. 2018 Dec 19;9(1):5390. doi: 10.1038/s41467-018-07812-8.
215 Association of Abnormal Left Ventricular Functional Reserve With Outcome in Heart Failure With Preserved Ejection Fraction.JACC Cardiovasc Imaging. 2018 Dec;11(12):1737-1746. doi: 10.1016/j.jcmg.2017.07.028. Epub 2017 Nov 15.
216 Periodontitis and bone metabolism in patients with advanced heart failure and after heart transplantation.ESC Heart Fail. 2017 May;4(2):169-177. doi: 10.1002/ehf2.12126. Epub 2017 Mar 1.
217 Discovery of novel small molecule TLR4 inhibitors as potent anti-inflammatory agents.Eur J Med Chem. 2018 Jun 25;154:253-266. doi: 10.1016/j.ejmech.2018.05.033. Epub 2018 May 22.
218 Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failure.Circ Heart Fail. 2011 Sep;4(5):659-68. doi: 10.1161/CIRCHEARTFAILURE.111.962563. Epub 2011 Jul 18.
219 Aggravated myocardial infarction-induced cardiac remodeling and heart failure in histamine-deficient mice.Sci Rep. 2017 Mar 8;7:44007. doi: 10.1038/srep44007.
220 mAKAP signalosomes - A nodal regulator of gene transcription associated with pathological cardiac remodeling.Cell Signal. 2019 Nov;63:109357. doi: 10.1016/j.cellsig.2019.109357. Epub 2019 Jul 9.
221 Cardiomyocyte Homeodomain-Interacting Protein Kinase 2 Maintains Basal Cardiac Function via Extracellular Signal-Regulated Kinase Signaling.Circulation. 2019 Nov 26;140(22):1820-1833. doi: 10.1161/CIRCULATIONAHA.119.040740. Epub 2019 Oct 4.
222 Acute detachment of hexokinase II from mitochondria modestly increases oxygen consumption of the intact mouse heart.Metabolism. 2017 Jul;72:66-74. doi: 10.1016/j.metabol.2017.04.008. Epub 2017 Apr 21.
223 Determination of HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies in heart failure patients.ESC Heart Fail. 2019 Apr;6(2):388-395. doi: 10.1002/ehf2.12406. Epub 2019 Jan 23.
224 Emergence of Members of TRAF and DUB of Ubiquitin Proteasome System in the Regulation of Hypertrophic Cardiomyopathy.Front Genet. 2018 Aug 21;9:336. doi: 10.3389/fgene.2018.00336. eCollection 2018.
225 miR-129-5p improves cardiac function in rats with chronic heart failure through targeting HMGB1.Mamm Genome. 2019 Oct;30(9-10):276-288. doi: 10.1007/s00335-019-09817-0. Epub 2019 Oct 23.
226 Loss of Endogenous HMGB2 Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice.Circ J. 2019 Jan 25;83(2):368-378. doi: 10.1253/circj.CJ-18-0925. Epub 2018 Nov 27.
227 The Protective Role of Heme Oxygenase-1 in Atherosclerotic Diseases.Int J Mol Sci. 2019 Jul 24;20(15):3628. doi: 10.3390/ijms20153628.
228 Shenfu Injection suppresses inflammation by targeting haptoglobin and pentraxin 3 in rats with chronic ischemic heart failure.Chin J Integr Med. 2015 Jan;21(1):22-8. doi: 10.1007/s11655-013-1440-8. Epub 2013 Mar 15.
229 The Histidine-Rich Calcium Binding Protein in Regulation of Cardiac Rhythmicity.Front Physiol. 2018 Sep 27;9:1379. doi: 10.3389/fphys.2018.01379. eCollection 2018.
230 Associations of Polymorphisms in HRH2, HRH3, DAO, and HNMT Genes with Risk of Chronic Heart Failure.Biomed Res Int. 2016;2016:1208476. doi: 10.1155/2016/1208476. Epub 2016 Feb 17.
231 Getting to the heart of intracellular glucocorticoid regeneration: 11-HSD1 in the myocardium.J Mol Endocrinol. 2017 Jan;58(1):R1-R13. doi: 10.1530/JME-16-0128. Epub 2016 Aug 23.
232 Heat shock protein 27 acts as a predictor of prognosis in chronic heart failure patients.Clin Chim Acta. 2017 Oct;473:127-132. doi: 10.1016/j.cca.2017.08.028. Epub 2017 Aug 24.
233 Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle.J Mol Cell Cardiol. 2007 Dec;43(6):767-79. doi: 10.1016/j.yjmcc.2007.08.019. Epub 2007 Sep 5.
234 Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.Circ Res. 2009 Jan 2;104(1):113-23. doi: 10.1161/CIRCRESAHA.108.180976. Epub 2008 Nov 20.
235 Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study.Am Heart J. 2007 Jan;153(1):54-8. doi: 10.1016/j.ahj.2006.10.019.
236 Insulin-like growth factor-1 short-period therapy improves cardiomyopathy stimulating cardiac progenitor cells survival in obese mice.Nutr Metab Cardiovasc Dis. 2020 Jan 3;30(1):151-161. doi: 10.1016/j.numecd.2019.09.001. Epub 2019 Sep 9.
237 Skeletal muscle molecular alterations precede whole-muscle dysfunction in NYHA Class II heart failure patients.Clin Interv Aging. 2012;7:489-97. doi: 10.2147/CIA.S37879. Epub 2012 Nov 12.
238 Comparison of Prognostic Usefulness of Serum Insulin-Like Growth Factor-Binding Protein 7 in Patients With Heart Failure and Preserved Versus Reduced Left Ventricular Ejection Fraction.Am J Cardiol. 2018 Jun 15;121(12):1558-1566. doi: 10.1016/j.amjcard.2018.02.041. Epub 2018 Mar 14.
239 New Role for Interleukin-13 Receptor 1 in Myocardial Homeostasis and Heart Failure.J Am Heart Assoc. 2017 May 20;6(5):e005108. doi: 10.1161/JAHA.116.005108.
240 Screening genes associated with elevated neutrophiltolymphocyte ratio in chronic heart failure.Mol Med Rep. 2018 Aug;18(2):1415-1422. doi: 10.3892/mmr.2018.9132. Epub 2018 Jun 5.
241 Soluble ST2 promotes oxidative stress and inflammation in cardiac fibroblasts: an in vitro and in vivo study in aortic stenosis.Clin Sci (Lond). 2019 Jul 17;133(14):1537-1548. doi: 10.1042/CS20190475. Print 2019 Jul 31.
242 The concentration of interleukin-33 in heart failure with reduced ejection fraction.Anatol J Cardiol. 2019 Jun;21(6):305-313. doi: 10.14744/AnatolJCardiol.2019.64614.
243 Activation of T Lymphocytes as a Novel Mechanism in Beta1-Adrenergic Receptor Autoantibody-Induced Cardiac Remodeling.Cardiovasc Drugs Ther. 2019 Apr;33(2):149-161. doi: 10.1007/s10557-019-06856-2.
244 Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish.Biomolecules. 2018 Nov 19;8(4):153. doi: 10.3390/biom8040153.
245 Chronic heart failure-related interventions after starting rosiglitazone in patients receiving insulin.Pharmacotherapy. 2004 Oct;24(10):1317-22. doi: 10.1592/phco.24.14.1317.43155.
246 Potential biomarkers for heart failure.J Cell Physiol. 2019 Jun;234(6):9467-9474. doi: 10.1002/jcp.27632. Epub 2018 Oct 28.
247 Ubiquitin-like protein ISG15 (interferon-stimulated gene of 15 kDa) in host defense against heart failure in a mouse model of virus-induced cardiomyopathy.Circulation. 2014 Oct 28;130(18):1589-600. doi: 10.1161/CIRCULATIONAHA.114.009847. Epub 2014 Aug 27.
248 Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure.Circ Res. 2002 Mar 8;90(4):458-64. doi: 10.1161/hh0402.105790.
249 Increased expression of fatty-acid and calcium metabolism genes in failing human heart.PLoS One. 2012;7(6):e37505. doi: 10.1371/journal.pone.0037505. Epub 2012 Jun 6.
250 Calcineurin-NFATc regulates type 2 inositol 1,4,5-trisphosphate receptor (InsP3R2) expression during cardiac remodeling.J Biol Chem. 2014 Feb 28;289(9):6188-98. doi: 10.1074/jbc.M113.495242. Epub 2014 Jan 10.
251 Role of inositol 1,4,5-trisphosphate receptors in regulating apoptotic signaling and heart failure.Heart Vessels. 1997;Suppl 12:53-7.
252 Long Noncoding RNA Kcna2 Antisense RNA Contributes to Ventricular Arrhythmias via Silencing Kcna2 in Rats With Congestive Heart Failure.J Am Heart Assoc. 2017 Dec 20;6(12):e005965. doi: 10.1161/JAHA.117.005965.
253 Analysis of the arrhythmogenic substrate in human heart failure.Cardiovasc Pathol. 2013 Mar-Apr;22(2):133-40. doi: 10.1016/j.carpath.2012.07.003. Epub 2012 Oct 1.
254 Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure.BMC Pharmacol Toxicol. 2019 Mar 6;20(1):16. doi: 10.1186/s40360-019-0294-x.
255 Atrial fibrillation and heart failure-associated remodeling of two-pore-domain potassium (K(2P)) channels in murine disease models: focus on TASK-1.Basic Res Cardiol. 2018 Jun 7;113(4):27. doi: 10.1007/s00395-018-0687-9.
256 Calcium-dependent potassium channels control proliferation of cardiac progenitor cells and bone marrow-derived mesenchymal stem cells.J Physiol. 2018 Jun;596(12):2359-2379. doi: 10.1113/JP275388. Epub 2018 May 5.
257 Impact of Renal Denervation on Atrial Arrhythmogenic Substrate in Ischemic Model of Heart Failure.J Am Heart Assoc. 2018 Jan 22;7(2):e007312. doi: 10.1161/JAHA.117.007312.
258 Three Cases of KCNT1 Mutations: Malignant Migrating Partial Seizures in Infancy with Massive Systemic to Pulmonary Collateral Arteries.J Pediatr. 2017 Dec;191:270-274. doi: 10.1016/j.jpeds.2017.08.057. Epub 2017 Oct 5.
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260 Leukocyte immunoglobulin-like receptor B4 (LILRB4) negatively mediates the pathological cardiac hypertrophy by suppressing fibrosis, inflammation and apoptosis via the activation of NF-B signaling.Biochem Biophys Res Commun. 2019 Jan 29;509(1):16-23. doi: 10.1016/j.bbrc.2018.11.137. Epub 2018 Dec 20.
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263 Induction of LOX by TGF-1/Smad/AP-1 signaling aggravates rat myocardial fibrosis and heart failure.IUBMB Life. 2019 Nov;71(11):1729-1739. doi: 10.1002/iub.2112. Epub 2019 Jul 18.
264 High Level of Lipoprotein(a) as Predictor for Recurrent Heart Failure in Patients with Chronic Heart Failure: a Cohort Study.Arq Bras Cardiol. 2019 Jul 18;113(2):197-204. doi: 10.5935/abc.20190120.
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267 Functions for the cardiomyokine, MANF, in cardioprotection, hypertrophy and heart failure.J Mol Cell Cardiol. 2011 Oct;51(4):512-7. doi: 10.1016/j.yjmcc.2010.10.008. Epub 2010 Oct 21.
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270 Mixed lineage kinase-3 prevents cardiac dysfunction and structural remodeling with pressure overload.Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H145-H159. doi: 10.1152/ajpheart.00029.2018. Epub 2018 Oct 26.
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272 Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure.ACS Med Chem Lett. 2017 Feb 8;8(3):316-320. doi: 10.1021/acsmedchemlett.6b00481. eCollection 2017 Mar 9.
273 Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy.Elife. 2017 Aug 22;6:e28118. doi: 10.7554/eLife.28118.
274 The Effect of Mecp2 on Heart Failure.Cell Physiol Biochem. 2018;47(6):2380-2387. doi: 10.1159/000491610. Epub 2018 Jul 10.
275 Reduced hybrid/complex N-glycosylation disrupts cardiac electrical signaling and calcium handling in a model of dilated cardiomyopathy.J Mol Cell Cardiol. 2019 Jul;132:13-23. doi: 10.1016/j.yjmcc.2019.05.001. Epub 2019 May 6.
276 Migrated T lymphocytes into malignant pleural effusions: an indicator of good prognosis in lung adenocarcinoma patients.Sci Rep. 2019 Feb 28;9(1):2996. doi: 10.1038/s41598-018-35840-3.
277 Predictive value of serum myostatin for the severity and clinical outcome of heart failure.Eur J Intern Med. 2019 Jun;64:33-40. doi: 10.1016/j.ejim.2019.04.017. Epub 2019 May 2.
278 Identification of cellular targets involved in cardiac failure caused by PKI in oncology: an approach combining pharmacovigilance and pharmacodynamics.Br J Clin Pharmacol. 2017 Jul;83(7):1544-1555. doi: 10.1111/bcp.13238. Epub 2017 Feb 14.
279 Carbohydrate antigen 125 in heart failure. New era in the monitoring and control of treatment.Med Clin (Barc). 2019 Apr 5;152(7):266-273. doi: 10.1016/j.medcli.2018.08.020. Epub 2018 Nov 12.
280 Shen'ge powder decreases the cardiomyocyte hypertrophy in chronic heart failure by activating the Rho protein/Rho-associated coiledcoil forming protein kinase signaling pathway.J Cell Biochem. 2019 Mar;120(3):3038-3045. doi: 10.1002/jcb.27386. Epub 2018 Nov 26.
281 Evaluations of the effect of HuangQi against heart failure based on comprehensive echocardiography index and metabonomics.Phytomedicine. 2018 Nov 15;50:205-212. doi: 10.1016/j.phymed.2018.04.027. Epub 2018 Apr 10.
282 TGF-1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.J Mol Cell Cardiol. 2017 Nov;112:49-57. doi: 10.1016/j.yjmcc.2017.08.015. Epub 2017 Sep 1.
283 Loss of p47phox subunit enhances susceptibility to biomechanical stress and heart failure because of dysregulation of cortactin and actin filaments.Circ Res. 2013 Jun 7;112(12):1542-56. doi: 10.1161/CIRCRESAHA.111.300299. Epub 2013 Apr 3.
284 Three-Dimensional Model of Human Nicotinamide Nucleotide Transhydrogenase (NNT) and Sequence-Structure Analysis of its Disease-Causing Variations.Hum Mutat. 2016 Oct;37(10):1074-84. doi: 10.1002/humu.23046. Epub 2016 Aug 8.
285 Deficiency of NOD1 Improves the -Adrenergic Modulation of Ca(2+) Handling in a Mouse Model of Heart Failure.Front Physiol. 2018 Jun 14;9:702. doi: 10.3389/fphys.2018.00702. eCollection 2018.
286 Eplerenone mimics features of the alternative activation in macrophages obtained from patients with heart failure and healthy volunteers.Eur J Pharmacol. 2014 Mar 5;726:96-108. doi: 10.1016/j.ejphar.2014.01.043.
287 NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase.Antioxid Redox Signal. 2019 Jul 1;31(1):39-58. doi: 10.1089/ars.2018.7548. Epub 2018 Dec 28.
288 Molecular and genetic aspects of guanylyl cyclase natriuretic peptide receptor-A in regulation of blood pressure and renal function.Physiol Genomics. 2018 Nov 1;50(11):913-928. doi: 10.1152/physiolgenomics.00083.2018. Epub 2018 Aug 31.
289 Identification of small molecule NPR-B antagonists by high throughput screening--potential use in heart failure.Naunyn Schmiedebergs Arch Pharmacol. 2014 Jan;387(1):5-14. doi: 10.1007/s00210-013-0940-6. Epub 2013 Dec 3.
290 A functional variant of the neuropeptide S receptor-1 gene modulates clinical outcomes and healthcare utilization in patients with systolic heart failure: results from the Interdisciplinary Network Heart Failure (INH) Study.Eur J Heart Fail. 2017 Mar;19(3):314-323. doi: 10.1002/ejhf.706. Epub 2016 Dec 18.
291 Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis.Cardiovasc Res. 2018 Oct 1;114(12):1617-1628. doi: 10.1093/cvr/cvy125.
292 Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts.Cardiovasc Res. 2004 Jan 1;61(1):87-93. doi: 10.1016/j.cardiores.2003.11.005.
293 Increased mortality and aggravation of heart failure in liver X receptor- knockout mice after myocardial infarction.Heart Vessels. 2016 Aug;31(8):1370-9. doi: 10.1007/s00380-015-0781-y. Epub 2016 Jan 11.
294 Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.Sci Rep. 2019 May 1;9(1):6801. doi: 10.1038/s41598-019-42592-1.
295 Cell type- and tissue-specific functions of ecto-5'-nucleotidase (CD73).Am J Physiol Cell Physiol. 2019 Dec 1;317(6):C1079-C1092. doi: 10.1152/ajpcell.00285.2019. Epub 2019 Aug 28.
296 Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy.J Mol Cell Cardiol. 2020 Jan;138:304-317. doi: 10.1016/j.yjmcc.2019.11.159. Epub 2019 Dec 10.
297 Role of oxidative stress-related biomarkers in heart failure: galectin 3, 1-antitrypsin and LOX-1: new therapeutic perspective?.Mol Cell Biochem. 2020 Jan;464(1-2):143-152. doi: 10.1007/s11010-019-03656-y. Epub 2019 Nov 29.
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299 Hippo Deficiency Leads to Cardiac Dysfunction Accompanied by Cardiomyocyte Dedifferentiation During Pressure Overload.Circ Res. 2019 Jan 18;124(2):292-305. doi: 10.1161/CIRCRESAHA.118.314048.
300 The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice.Biochem Biophys Res Commun. 2016 Oct 28;479(4):708-714. doi: 10.1016/j.bbrc.2016.09.147. Epub 2016 Sep 29.
301 Loss of function mutation in the P2X7, a ligand-gated ion channel gene associated with hypertrophic cardiomyopathy.Purinergic Signal. 2019 Jun;15(2):205-210. doi: 10.1007/s11302-019-09660-7. Epub 2019 May 31.
302 Association of High Mortality With Postoperative Myocardial Infarction After Major Vascular Surgery Despite Use of Evidence-Based Therapies.JAMA Surg. 2020 Feb 1;155(2):131-137. doi: 10.1001/jamasurg.2019.4908.
303 Increase in cardiac P2X1-and P2Y2-receptor mRNA levels in congestive heart failure.Life Sci. 1999;65(11):1195-206. doi: 10.1016/s0024-3205(99)00353-7.
304 Palliative Care in Heart Failure: The PAL-HF Randomized, Controlled Clinical Trial.J Am Coll Cardiol. 2017 Jul 18;70(3):331-341. doi: 10.1016/j.jacc.2017.05.030.
305 PARP-1 inhibition attenuates cardiac fibrosis induced by myocardial infarction through regulating autophagy.Biochem Biophys Res Commun. 2018 Sep 10;503(3):1625-1632. doi: 10.1016/j.bbrc.2018.07.091. Epub 2018 Jul 21.
306 Molecular Implications of Natriuretic Peptides in the Protection from Hypertension and Target Organ Damage Development.Int J Mol Sci. 2019 Feb 13;20(4):798. doi: 10.3390/ijms20040798.
307 Recent major advances in cardiovascular pharmacotherapy.Eur J Clin Pharmacol. 2018 Jul;74(7):853-862. doi: 10.1007/s00228-018-2453-1. Epub 2018 Mar 27.
308 A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction.Circulation. 2020 Jan 21;141(3):217-233. doi: 10.1161/CIRCULATIONAHA.119.042178. Epub 2019 Dec 5.
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310 Contribution of BKCa channels to vascular tone regulation by PDE3 and PDE4 is lost in heart failure.Cardiovasc Res. 2019 Jan 1;115(1):130-144. doi: 10.1093/cvr/cvy161.
311 Rolipram, a PDE4 Inhibitor, Enhances the Inotropic Effect of Rat Heart by Activating SERCA2a.Front Pharmacol. 2019 Mar 22;10:221. doi: 10.3389/fphar.2019.00221. eCollection 2019.
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315 Metabolic remodeling of cardiomyocytes identified in phosphoinositide-dependent kinase 1-deficient mice.Biochem J. 2019 Jul 9;476(13):1943-1954. doi: 10.1042/BCJ20190105.
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317 The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on -adrenoceptors.Biochem Biophys Res Commun. 2019 Dec 3;520(2):327-332. doi: 10.1016/j.bbrc.2019.09.135. Epub 2019 Oct 8.
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324 Heart Failure Stimulates Tumor Growth by Circulating Factors.Circulation. 2018 Aug 14;138(7):678-691. doi: 10.1161/CIRCULATIONAHA.117.030816.
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335 Impact of Race on the Association of Mineral Metabolism With Heart Failure: the Multi-Ethnic Study of Atherosclerosis.J Clin Endocrinol Metab. 2020 Apr 1;105(4):e1144-51. doi: 10.1210/clinem/dgz218.
336 The role of PI3-K/Akt signal pathway in the antagonist effect of CEPO on CHF rats.Exp Ther Med. 2018 Dec;16(6):5161-5165. doi: 10.3892/etm.2018.6822. Epub 2018 Oct 2.
337 Protein tyrosine phosphatase 1B regulates endothelial endoplasmic reticulum stress; role in endothelial dysfunction.Vascul Pharmacol. 2018 Oct;109:36-44. doi: 10.1016/j.vph.2018.05.011. Epub 2018 Jun 9.
338 Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy.Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2325-33. doi: 10.1152/ajpheart.01041.2004. Epub 2005 Sep 9.
339 Tyrosine phosphorylation of RACK1 triggers cardiomyocyte hypertrophy by regulating the interaction between p300 and GATA4.Biochim Biophys Acta. 2016 Sep;1862(9):1544-57. doi: 10.1016/j.bbadis.2016.05.006. Epub 2016 May 18.
340 Exchange-protein activated by cAMP (EPAC) regulates L-type calcium channel in atrial fibrillation of heart failure model.Eur Rev Med Pharmacol Sci. 2019 Mar;23(5):2200-2207. doi: 10.26355/eurrev_201903_17267.
341 Plasma Level of Retinol-Binding Protein 4, N-Terminal proBNP and Renal Function in Older Patients Hospitalized for Heart Failure.Cardiorenal Med. 2018;8(3):237-248. doi: 10.1159/000489403. Epub 2018 Jul 4.
342 Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice.J Mol Cell Cardiol. 2017 Jul;108:194-202. doi: 10.1016/j.yjmcc.2017.06.007. Epub 2017 Jun 19.
343 Expression of ten RGS proteins in human myocardium: functional characterization of an upregulation of RGS4 in heart failure.Cardiovasc Res. 2002 Sep;55(4):778-86. doi: 10.1016/s0008-6363(02)00459-5.
344 Clinical Impact of ABO and Rhesus D Blood Type Groups in Patients With Chronic Heart Failure.Am J Cardiol. 2018 Aug 1;122(3):413-419. doi: 10.1016/j.amjcard.2018.04.018. Epub 2018 May 2.
345 Intraabdominal pressure and worsening renal function during decompensations of heart failure. A preliminary report from the PIA study.Rev Clin Esp (Barc). 2019 Jun-Jul;219(5):229-235. doi: 10.1016/j.rce.2018.09.022. Epub 2018 Dec 20.
346 A context-specific cardiac -catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.Nucleic Acids Res. 2018 Apr 6;46(6):2850-2867. doi: 10.1093/nar/gky049.
347 Molecular mechanisms of heart failure: insights from Drosophila.Heart Fail Rev. 2017 Jan;22(1):91-98. doi: 10.1007/s10741-016-9590-3.
348 Cost-of-illness studies in heart failure: a systematic review 2004-2016.BMC Cardiovasc Disord. 2018 May 2;18(1):74. doi: 10.1186/s12872-018-0815-3.
349 Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure.Circulation. 2018 Sep 11;138(11):1144-1154. doi: 10.1161/CIRCULATIONAHA.117.032703.
350 Identification of cardiac hemo-vascular precursors and their requirement of sphingosine-1-phosphate receptor 1 for heart development.Sci Rep. 2017 Mar 24;7:45205. doi: 10.1038/srep45205.
351 Chagas disease is associated with a worse prognosis at 1-year follow-up after implantable cardioverter-defibrillator for secondary prevention in heart failure patients.J Cardiovasc Electrophysiol. 2019 Nov;30(11):2448-2452. doi: 10.1111/jce.14164. Epub 2019 Sep 18.
352 Sacubitril/valsartan: An important piece in the therapeutic puzzle of heart failure.Rev Port Cardiol. 2017 Sep;36(9):655-668. doi: 10.1016/j.repc.2016.11.013. Epub 2017 Aug 23.
353 SCN5A: the greatest HITS collection.J Clin Invest. 2018 Mar 1;128(3):913-915. doi: 10.1172/JCI99927. Epub 2018 Feb 19.
354 Correction: Increased Levels of Plasma Soluble Sema4D in Patients with Heart Failure.PLoS One. 2019 Mar 28;14(3):e0214894. doi: 10.1371/journal.pone.0214894. eCollection 2019.
355 Safety, feasibility and effectiveness of first in-human administration of muscle-derived stem/progenitor cells modified with connexin-43 gene for treatment of advanced chronic heart failure.Eur J Heart Fail. 2017 Jan;19(1):148-157. doi: 10.1002/ejhf.700.
356 Prognostic value of instrumental activity of daily living in initial heart failure hospitalization patients aged 65years or older.Heart Vessels. 2020 Mar;35(3):360-366. doi: 10.1007/s00380-019-01490-2. Epub 2019 Sep 5.
357 Serum-glucocorticoid-regulated kinase 1 contributes to mechanical stretch-induced inflammatory responses in cardiac fibroblasts.Mol Cell Biochem. 2018 Aug;445(1-2):67-78. doi: 10.1007/s11010-017-3252-1. Epub 2017 Dec 14.
358 Protective mechanism of SIRT1 on Hcy-induced atrial fibrosis mediated by TRPC3.J Cell Mol Med. 2020 Jan;24(1):488-510. doi: 10.1111/jcmm.14757. Epub 2019 Nov 4.
359 Cardioprotective Effects of SIRT6 in a Mouse Model of Transverse Aortic Constriction-Induced Heart Failure.Front Physiol. 2017 Jun 13;8:394. doi: 10.3389/fphys.2017.00394. eCollection 2017.
360 AST-120, an Adsorbent of Uremic Toxins, Improves the Pathophysiology of Heart Failure in Conscious Dogs.Cardiovasc Drugs Ther. 2019 Jun;33(3):277-286. doi: 10.1007/s10557-019-06875-z.
361 Cardiac acetylcholine inhibits ventricular remodeling and dysfunction under pathologic conditions.FASEB J. 2016 Feb;30(2):688-701. doi: 10.1096/fj.15-277046. Epub 2015 Oct 19.
362 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes.Biochem Biophys Res Commun. 2009 Nov 13;389(2):315-20. doi: 10.1016/j.bbrc.2009.08.136. Epub 2009 Aug 29.
363 Inhibition of AT1 receptors by losartan affects myocardial slow force response in healthy but not in monocrotaline-treated young rats.Gen Physiol Biophys. 2018 Mar;37(2):153-162. doi: 10.4149/gpb_2017025.
364 Pretreatment with KGA-2727, a selective SGLT1 inhibitor, is protective against myocardial infarction-induced ventricular remodeling and heart failure in mice.J Pharmacol Sci. 2020 Jan;142(1):16-25. doi: 10.1016/j.jphs.2019.11.001. Epub 2019 Nov 7.
365 Polymorphism of SLC6A2 gene does not influence outcome of myocardial (123)I-mIBG scintigraphy in patients with chronic heart failure.J Nucl Cardiol. 2018 Jun;25(3):900-906. doi: 10.1007/s12350-016-0722-x. Epub 2016 Nov 14.
366 Characterizing Vascular Dysfunction in Genetically Modified Mice through the Hyperoxia Model.Int J Mol Sci. 2019 May 2;20(9):2178. doi: 10.3390/ijms20092178.
367 The role of splanchnic congestion and the intestinal microenvironment in the pathogenesis of advanced heart failure.Curr Opin Support Palliat Care. 2019 Mar;13(1):24-30. doi: 10.1097/SPC.0000000000000414.
368 Influence of OATP1B1 and OATP1B3 mutations and glomerular filtration rate on trough serum digoxin concentration in the Chinese population: A prospective cohort study.Medicine (Baltimore). 2019 Apr;98(14):e15088. doi: 10.1097/MD.0000000000015088.
369 Small-hairpin RNA and pharmacological targeting of neutral sphingomyelinase prevent diaphragm weakness in rats with heart failure and reduced ejection fraction.Am J Physiol Lung Cell Mol Physiol. 2019 Apr 1;316(4):L679-L690. doi: 10.1152/ajplung.00516.2018. Epub 2019 Jan 31.
370 Dysfunction in the II spectrin-dependent cytoskeleton underlies human arrhythmia.Circulation. 2015 Feb 24;131(8):695-708. doi: 10.1161/CIRCULATIONAHA.114.013708. Epub 2015 Jan 28.
371 Identification of Potential Gene Interactions in Heart Failure Caused by Idiopathic Dilated Cardiomyopathy.Med Sci Monit. 2018 Oct 28;24:7697-7709. doi: 10.12659/MSM.912984.
372 Stanniocalcin-1 is a naturally occurring L-channel inhibitor in cardiomyocytes: relevance to human heart failure.Am J Physiol Heart Circ Physiol. 2003 Jul;285(1):H442-8. doi: 10.1152/ajpheart.01071.2002. Epub 2003 Mar 27.
373 Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction. Cardiovasc Diabetol. 2018 Apr 30;17(1):63.
374 A systematic review of large scale and heterogeneous gene array data in heart failure.J Mol Cell Cardiol. 2005 Mar;38(3):425-32. doi: 10.1016/j.yjmcc.2004.12.016.
375 Genomic profiling reveals the potential role of TCL1A and MDR1 deficiency in chemotherapy-induced cardiotoxicity.Int J Biol Sci. 2013 Apr 22;9(4):350-60. doi: 10.7150/ijbs.6058. Print 2013.
376 Telomere attrition and Chk2 activation in human heart failure.Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5378-83. doi: 10.1073/pnas.0836098100. Epub 2003 Apr 17.
377 The NADPH oxidase inhibitor apocynin improves cardiac sympathetic nerve terminal innervation and function in heart failure.Exp Physiol. 2019 Nov;104(11):1638-1649. doi: 10.1113/EP087552. Epub 2019 Oct 10.
378 Tissue thyroid hormones and thyronamines.Heart Fail Rev. 2016 Jul;21(4):373-90. doi: 10.1007/s10741-016-9553-8.
379 The long noncoding RNA XIST regulates cardiac hypertrophy by targeting miR-101.J Cell Physiol. 2019 Aug;234(8):13680-13692. doi: 10.1002/jcp.28047. Epub 2019 Jan 3.
380 Thymosin Beta-4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction.J Am Heart Assoc. 2017 Jun 13;6(6):e005586. doi: 10.1161/JAHA.117.005586.
381 TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart.J Mol Cell Cardiol. 2018 Aug;121:107-123. doi: 10.1016/j.yjmcc.2018.07.003. Epub 2018 Jul 5.
382 Dysfunctional and Proinflammatory Regulatory T-Lymphocytes Are Essential for Adverse Cardiac Remodeling in Ischemic Cardiomyopathy.Circulation. 2019 Jan 8;139(2):206-221. doi: 10.1161/CIRCULATIONAHA.118.036065.
383 Potential of the Cardiovascular Drug Levosimendan in the Management of Amyotrophic Lateral Sclerosis: An Overview of a Working Hypothesis.J Cardiovasc Pharmacol. 2019 Nov;74(5):389-399. doi: 10.1097/FJC.0000000000000728.
384 Prognostic value of very low plasma concentrations of troponin T in patients with stable chronic heart failure.Circulation. 2007 Sep 11;116(11):1242-9. doi: 10.1161/CIRCULATIONAHA.106.655076. Epub 2007 Aug 13.
385 Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers.Cell Death Dis. 2017 Jan 19;8(1):e2564. doi: 10.1038/cddis.2016.418.
386 Role of brain serotonin dysfunction in the pathophysiology of congestive heart failure.J Mol Cell Cardiol. 2012 Dec;53(6):760-7. doi: 10.1016/j.yjmcc.2012.08.006. Epub 2012 Aug 19.
387 Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure.Int J Cardiol. 2019 Mar 15;279:141-144. doi: 10.1016/j.ijcard.2018.12.076. Epub 2018 Dec 28.
388 Refractory congestive heart failure following delayed pericardectomy in a 12-year-old child with Mulibrey nanism due to a novel mutation in TRIM37.Eur J Pediatr. 2013 Oct;172(10):1415-8. doi: 10.1007/s00431-013-1962-2. Epub 2013 Feb 6.
389 Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure.Am J Physiol Heart Circ Physiol. 2019 Apr 1;316(4):H862-H872. doi: 10.1152/ajpheart.00696.2018. Epub 2019 Feb 1.
390 Inhibition of TRPC1 prevents cardiac hypertrophy via NF-B signaling pathway in human pluripotent stem cell-derived cardiomyocytes.J Mol Cell Cardiol. 2019 Jan;126:143-154. doi: 10.1016/j.yjmcc.2018.10.020. Epub 2018 Nov 10.
391 Role of TRPC3 and TRPC6 channels in the myocardial response to stretch: Linking physiology and pathophysiology.Prog Biophys Mol Biol. 2017 Nov;130(Pt B):264-272. doi: 10.1016/j.pbiomolbio.2017.06.010. Epub 2017 Jun 20.
392 Involvement of transient receptor potential proteins in cardiac hypertrophy.Biochim Biophys Acta. 2007 Aug;1772(8):885-94. doi: 10.1016/j.bbadis.2007.02.007. Epub 2007 Feb 24.
393 Resiniferatoxin reduces ventricular arrhythmias in heart failure via selectively blunting cardiac sympathetic afferent projection into spinal cord in rats.Eur J Pharmacol. 2020 Jan 15;867:172836. doi: 10.1016/j.ejphar.2019.172836. Epub 2019 Dec 4.
394 Blockade of TRPV2 is a Novel Therapy for Cardiomyopathy in Muscular Dystrophy.Int J Mol Sci. 2019 Aug 7;20(16):3844. doi: 10.3390/ijms20163844.
395 Puerarin inhibits apoptosis and inflammation in myocardial cells via PPAR expression in rats with chronic heart failure.Exp Ther Med. 2019 Nov;18(5):3347-3356. doi: 10.3892/etm.2019.7984. Epub 2019 Sep 6.
396 Novel Biomarkers of Heart Failure.Adv Clin Chem. 2017;79:93-152. doi: 10.1016/bs.acc.2016.09.002. Epub 2016 Nov 3.
397 Rodent heart failure models do not reflect the human circulating microRNA signature in heart failure.PLoS One. 2017 May 5;12(5):e0177242. doi: 10.1371/journal.pone.0177242. eCollection 2017.
398 Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure.Int J Med Sci. 2017 Jul 20;14(9):891-895. doi: 10.7150/ijms.19854. eCollection 2017.
399 UCP3 Ablation Exacerbates High-Salt Induced Cardiac Hypertrophy and Cardiac Dysfunction.Cell Physiol Biochem. 2018;46(4):1683-1692. doi: 10.1159/000489244. Epub 2018 Apr 20.
400 A novel urotensin II receptor antagonist, KR-36996, improved cardiac function and attenuated cardiac hypertrophy in experimental heart failure.Eur J Pharmacol. 2017 Mar 15;799:94-102. doi: 10.1016/j.ejphar.2017.02.003. Epub 2017 Feb 3.
401 Selection of reference genes for gene expression studies in heart failure for left and right ventricles.Gene. 2017 Jul 15;620:30-35. doi: 10.1016/j.gene.2017.04.006. Epub 2017 Apr 5.
402 Correction: Tongxinluo protects against pressure overload-induced heart failure in mice involving VEGF/Akt/eNOS pathway activation.PLoS One. 2019 Aug 1;14(8):e0220845. doi: 10.1371/journal.pone.0220845. eCollection 2019.
403 Increased vascular endothelial growth factor D is associated with atrial fibrillation and ischaemic stroke.Heart. 2019 Apr;105(7):553-558. doi: 10.1136/heartjnl-2018-313684. Epub 2018 Oct 16.
404 The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.Pharmacogenomics J. 2020 Apr;20(2):277-284. doi: 10.1038/s41397-019-0116-y. Epub 2019 Oct 25.
405 Effects of a fully magnetically levitated centrifugal-flow or axial-flow left ventricular assist device on von Willebrand factor: A prospective multicenter clinical trial.J Heart Lung Transplant. 2019 Aug;38(8):806-816. doi: 10.1016/j.healun.2019.05.006. Epub 2019 May 17.
406 Genetic expression profiles during physiological and pathological cardiac hypertrophy and heart failure in rats.Physiol Genomics. 2005 Mar 21;21(1):34-42. doi: 10.1152/physiolgenomics.00226.2004. Epub 2004 Dec 28.
407 Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure.Int J Cardiol. 2009 May 1;134(1):82-90. doi: 10.1016/j.ijcard.2008.01.043. Epub 2008 Jul 11.
408 Myocardial expression of survivin, an apoptosis inhibitor, in aging and heart failure. An experimental study in the spontaneously hypertensive rat.Int J Cardiol. 2006 Aug 28;111(3):371-6. doi: 10.1016/j.ijcard.2005.07.061. Epub 2005 Oct 27.
409 Heart failure and angiotensin II modulate atrial Pitx2c promotor methylation.Clin Exp Pharmacol Physiol. 2013 Jun;40(6):379-84. doi: 10.1111/1440-1681.12089.
410 Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes.J Mol Cell Cardiol. 2009 Jan;46(1):59-66. doi: 10.1016/j.yjmcc.2008.09.714. Epub 2008 Oct 19.
411 Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes.Sci Rep. 2019 May 21;9(1):7658. doi: 10.1038/s41598-019-44139-w.
412 Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents.J Clin Invest. 2010 Feb;120(2):408-21. doi: 10.1172/JCI39778. Epub 2010 Jan 4.
413 Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat.Cardiovasc Res. 2000 May;46(2):307-15. doi: 10.1016/s0008-6363(00)00029-8.
414 Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due to myocardial infarction.J Cell Mol Med. 2004 Oct-Dec;8(4):526-36. doi: 10.1111/j.1582-4934.2004.tb00477.x.
415 MLP-deficient human pluripotent stem cell derived cardiomyocytes develop hypertrophic cardiomyopathy and heart failure phenotypes due to abnormal calcium handling.Cell Death Dis. 2019 Aug 13;10(8):610. doi: 10.1038/s41419-019-1826-4.
416 Increased late sodium currents are related to transcription of neuronal isoforms in a pressure-overload model.Eur J Heart Fail. 2009 Aug;11(8):749-57. doi: 10.1093/eurjhf/hfp092. Epub 2009 Jul 7.
417 Manifestations of and risk factors for acute myocardial injury after acute organophosphorus pesticide poisoning.Medicine (Baltimore). 2019 Feb;98(6):e14371. doi: 10.1097/MD.0000000000014371.
418 Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation.Cancer Chemother Pharmacol. 2011 Jun;67(6):1381-8. doi: 10.1007/s00280-010-1441-7. Epub 2010 Aug 31.
419 Chronic Pressure Overload Results in Deficiency of Mitochondrial Membrane Transporter ABCB7 Which Contributes to Iron Overload, Mitochondrial Dysfunction, Metabolic Shift and Worsens Cardiac Function.Sci Rep. 2019 Sep 11;9(1):13170. doi: 10.1038/s41598-019-49666-0.
420 TREK-1 (K(2P)2.1) K(+) channels are suppressed in patients with atrial fibrillation and heart failure and provide therapeutic targets for rhythm control.Basic Res Cardiol. 2017 Jan;112(1):8. doi: 10.1007/s00395-016-0597-7. Epub 2016 Dec 22.
421 Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy.Sci Rep. 2017 Apr 18;7:46369. doi: 10.1038/srep46369.
422 Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy. Am J Pathol. 2011 Jun;178(6):2547-59.
423 Paradoxical Effects of Sodium-Calcium Exchanger Inhibition on Torsade de Pointes and Early Afterdepolarization in a Heart Failure Rabbit Model.J Cardiovasc Pharmacol. 2018 Aug;72(2):97-105. doi: 10.1097/FJC.0000000000000598.
424 A variant in the heart-specific fatty acid transport protein 6 is associated with lower fasting and postprandial TAG, blood pressure and left ventricular hypertrophy.Br J Nutr. 2012 May;107(10):1422-8. doi: 10.1017/S0007114511004727. Epub 2011 Sep 16.
425 Catestatin: A Master Regulator of Cardiovascular Functions.Curr Med Chem. 2018;25(11):1352-1374. doi: 10.2174/0929867324666170425100416.
426 Frequency and prognostic impact of mid-expiratory flow reduction in stable patients six months after hospitalisation for heart failure with reduced ejection fraction.Int J Cardiol. 2017 Jan 15;227:727-733. doi: 10.1016/j.ijcard.2016.10.071. Epub 2016 Oct 28.
427 RNA SEQ Analysis Indicates that the AE3 Cl(-)/HCO(3)(-) Exchanger Contributes to Active Transport-Mediated CO(2) Disposal in Heart.Sci Rep. 2017 Aug 4;7(1):7264. doi: 10.1038/s41598-017-07585-y.
428 Protease activated receptor-2 contributes to heart failure.PLoS One. 2013 Nov 27;8(11):e81733. doi: 10.1371/journal.pone.0081733. eCollection 2013.
429 Activation and Inhibition of Sodium-Hydrogen Exchanger Is a Mechanism That Links the Pathophysiology and Treatment of Diabetes Mellitus With That of Heart Failure.Circulation. 2017 Oct 17;136(16):1548-1559. doi: 10.1161/CIRCULATIONAHA.117.030418.
430 Association Between Plasma Neutrophil Gelatinase-Associated Lipocalin and Cardiac Disease Hospitalizations and Deaths in Older Women.J Am Heart Assoc. 2019 Jan 8;8(1):e011028. doi: 10.1161/JAHA.118.011028.
431 Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study.PLoS One. 2018 Dec 17;13(12):e0208042. doi: 10.1371/journal.pone.0208042. eCollection 2018.
432 Early versus delayed invasive strategy in patients with non-ST-elevation acute coronary syndrome and concomitant congestive heart failure.J Cardiol. 2019 Oct;74(4):320-327. doi: 10.1016/j.jjcc.2019.03.006.
433 Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury.J Am Heart Assoc. 2015 Jul 31;4(8):e002272. doi: 10.1161/JAHA.115.002272.
434 Molecular Mechanism of the Association Between Atrial Fibrillation and Heart Failure Includes Energy Metabolic Dysregulation Due to Mitochondrial Dysfunction.J Card Fail. 2019 Nov;25(11):911-920. doi: 10.1016/j.cardfail.2019.08.005. Epub 2019 Aug 12.
435 Low-Dose Anthracycline and Risk of Heart Failure in a Pharmacokinetic Model of Human Myocardium Exposure: Analog Specificity and Role of Secondary Alcohol Metabolites.J Pharmacol Exp Ther. 2018 Feb;364(2):323-331. doi: 10.1124/jpet.117.246140. Epub 2017 Dec 8.
436 A Computational Approach for Understanding the Interactions between Graphene Oxide and Nucleoside Diphosphate Kinase with Implications for Heart Failure.Nanomaterials (Basel). 2018 Jan 23;8(2):57. doi: 10.3390/nano8020057.
437 Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure.Physiol Res. 2017 Mar 31;66(1):29-39. doi: 10.33549/physiolres.933350. Epub 2016 Oct 26.
438 Protective effects of low-dose rosuvastatin on isoproterenol-induced chronic heart failure in rats by regulation of DDAH-ADMA-NO pathway.Cardiovasc Ther. 2017 Apr;35(2). doi: 10.1111/1755-5922.12241.
439 Keeping heart homeostasis in check through the balance of iron metabolism.Acta Physiol (Oxf). 2020 Jan;228(1):e13324. doi: 10.1111/apha.13324. Epub 2019 Jun 19.
440 Enhanced Redox State and Efficiency of Glucose Oxidation With miR Based Suppression of Maladaptive NADPH-Dependent Malic Enzyme 1 Expression in Hypertrophied Hearts.Circ Res. 2018 Mar 16;122(6):836-845. doi: 10.1161/CIRCRESAHA.118.312660. Epub 2018 Jan 31.
441 Serum N(1)-methylnicotinamide is Associated with Left Ventricular Systolic Dysfunction in Chinese.Sci Rep. 2018 Jun 5;8(1):8581. doi: 10.1038/s41598-018-26956-7.
442 A Human Study to Evaluate Safety, Tolerability, and Cyclic GMP Activating Properties of Cenderitide in Subjects With Stable Chronic Heart Failure.Clin Pharmacol Ther. 2018 Sep;104(3):546-552. doi: 10.1002/cpt.974. Epub 2018 Jan 11.
443 OPLAH ablation leads to accumulation of 5-oxoproline, oxidative stress, fibrosis, and elevated fillings pressures: a murine model for heart failure with a preserved ejection fraction.Cardiovasc Res. 2018 Dec 1;114(14):1871-1882. doi: 10.1093/cvr/cvy187.
444 Paraoxonase 2 prevents the development of heart failure.Free Radic Biol Med. 2018 Jun;121:117-126. doi: 10.1016/j.freeradbiomed.2018.04.583. Epub 2018 May 2.
445 Non classical Monocytes Levels, Increased by Subcutaneous Fat-Secretome, Are Associated with Less Rehospitalization after Heart Failure Admission.J Cardiovasc Transl Res. 2017 Feb;10(1):16-26. doi: 10.1007/s12265-016-9724-y. Epub 2016 Dec 29.
446 Association between right ventricle two- and three-dimensional echocardiography and exercise capacity in patients with reduced left ventricular ejection fraction.PLoS One. 2018 Jun 21;13(6):e0199439. doi: 10.1371/journal.pone.0199439. eCollection 2018.
447 Soluble ST2 protein and hospitalizations due to worsening chronic heart failure during a one-year follow-up in a population with reduced ejection fraction.Adv Clin Exp Med. 2017 Sep;26(6):931-938. doi: 10.17219/acem/63005.
448 Pharmacokinetics of R- and S-carvedilol in routinely treated Japanese patients with heart failure.Biol Pharm Bull. 2008 May;31(5):976-80. doi: 10.1248/bpb.31.976.
449 Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats.J Clin Invest. 2008 Mar;118(3):975-83. doi: 10.1172/JCI32824.
450 Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients with myoadenylate deaminase deficiency.PLoS One. 2017 Nov 2;12(11):e0187266. doi: 10.1371/journal.pone.0187266. eCollection 2017.
451 MiR-1a-3p mitigates isoproterenol-induced heart failure by enhancing the expression of mitochondrial ND1 and COX1.Exp Cell Res. 2019 May 1;378(1):87-97. doi: 10.1016/j.yexcr.2019.03.012. Epub 2019 Mar 7.
452 The Human Myotrophin Variant Attenuates MicroRNA-Let-7 Binding Ability but Not Risk of Left Ventricular Hypertrophy in Human Essential Hypertension.PLoS One. 2015 Aug 14;10(8):e0135526. doi: 10.1371/journal.pone.0135526. eCollection 2015.
453 Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery.Circulation. 2019 Jan 22;139(4):489-501. doi: 10.1161/CIRCULATIONAHA.118.035774. Epub 2018 Nov 11.
454 Serelaxin (recombinant human relaxin-2) treatment affects the endogenous synthesis of long chain poly-unsaturated fatty acids and induces substantial alterations of lipidome and metabolome profiles in rat cardiac tissue.Pharmacol Res. 2019 Jun;144:51-65. doi: 10.1016/j.phrs.2019.04.009. Epub 2019 Apr 5.
455 Eligibility of sodium-glucose co-transporter-2 inhibitors among patients with diabetes mellitus admitted for heart failure.ESC Heart Fail. 2020 Feb;7(1):274-278. doi: 10.1002/ehf2.12528. Epub 2019 Nov 20.
456 CTCF inhibits endoplasmic reticulum stress and apoptosis in cardiomyocytes by upregulating RYR2 via inhibiting S100A1.Life Sci. 2020 Feb 1;242:117158. doi: 10.1016/j.lfs.2019.117158. Epub 2019 Dec 16.
457 Ankyrin Repeat Domain 1 Protein: A Functionally Pleiotropic Protein with Cardiac Biomarker Potential.Int J Mol Sci. 2017 Jun 26;18(7):1362. doi: 10.3390/ijms18071362.
458 (Pro)renin Receptor Blockade Ameliorates Heart Failure Caused by Chronic Kidney Disease.J Card Fail. 2019 Apr;25(4):286-300. doi: 10.1016/j.cardfail.2019.02.009. Epub 2019 Feb 13.
459 Common Variants in TRDN and CALM1 Are Associated with Risk of Sudden Cardiac Death in Chronic Heart Failure Patients in Chinese Han Population.PLoS One. 2015 Jul 21;10(7):e0132459. doi: 10.1371/journal.pone.0132459. eCollection 2015.
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517 Assessment of Safety and Effectiveness of the Extracorporeal Continuous-Flow Ventricular Assist Device (BR16010) Use as a Bridge-to-Decision Therapy for Severe Heart Failure or Refractory Cardiogenic Shock: Study Protocol for Single-Arm Non-randomized, Uncontrolled, and Investigator-Initiated Clinical Trial.Cardiovasc Drugs Ther. 2018 Aug;32(4):373-379. doi: 10.1007/s10557-018-6796-8.
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529 Population Pharmacokinetics and Pharmacodynamics of Apixaban Linking Its Plasma Concentration to Intrinsic Activated Coagulation Factor X Activity in Japanese Patients with Atrial Fibrillation.AAPS J. 2019 Jun 24;21(5):80. doi: 10.1208/s12248-019-0353-7.
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532 Risk and Temporal Changes of Heart Failure Among 5-Year Childhood Cancer Survivors: a DCOG-LATER Study.J Am Heart Assoc. 2019 Jan 8;8(1):e009122. doi: 10.1161/JAHA.118.009122.
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535 Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure.J Lipid Res. 2009 Aug;50(8):1600-8. doi: 10.1194/jlr.M800561-JLR200. Epub 2008 Nov 10.
536 Pancreatic exocrine insufficiency in patients with chronic heart failure and its possible association with appetite loss.PLoS One. 2017 Nov 20;12(11):e0187804. doi: 10.1371/journal.pone.0187804. eCollection 2017.
537 Sleep Apnea and Heart Failure With a Reduced Ejection Fraction Among Persons Living With Human Immunodeficiency Virus.Clin Infect Dis. 2018 Jul 18;67(3):447-455. doi: 10.1093/cid/ciy216.
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548 All-trans retinoic acid attenuates isoproterenol-induced cardiac dysfunction through Crabp1 to dampen CaMKII activation.Eur J Pharmacol. 2019 Sep 5;858:172485. doi: 10.1016/j.ejphar.2019.172485. Epub 2019 Jun 22.
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550 Combination of Circulating Type I Collagen-Related Biomarkers Is AssociatedWith AtrialFibrillation.J Am Coll Cardiol. 2019 Apr 2;73(12):1398-1410. doi: 10.1016/j.jacc.2018.12.074.
551 Zebrafish cysteine and glycine-rich protein 3 is essential for mechanical stability in skeletal muscles.Biochem Biophys Res Commun. 2019 Apr 9;511(3):604-611. doi: 10.1016/j.bbrc.2019.02.115. Epub 2019 Feb 28.
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554 Cytokine-Like 1 Regulates Cardiac Fibrosis via Modulation of TGF- Signaling.PLoS One. 2016 Nov 11;11(11):e0166480. doi: 10.1371/journal.pone.0166480. eCollection 2016.
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562 Cardiac Biomarkers Predict Large Vessel Occlusion in Patients with Ischemic Stroke.J Stroke Cerebrovasc Dis. 2019 Jun;28(6):1726-1731. doi: 10.1016/j.jstrokecerebrovasdis.2019.02.013. Epub 2019 Mar 19.
563 Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix.J Am Heart Assoc. 2018 Oct 16;7(20):e010025. doi: 10.1161/JAHA.118.010025.
564 BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure.Sci Transl Med. 2017 May 17;9(390):eaah5084. doi: 10.1126/scitranslmed.aah5084.
565 Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice.Cell Tissue Res. 2020 Apr;380(1):143-153. doi: 10.1007/s00441-019-03126-3. Epub 2019 Dec 7.
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567 High risk of heart failure associated with desmoglein-2 mutations compared to plakophilin-2 mutations in arrhythmogenic right ventricular cardiomyopathy/dysplasia.Eur J Heart Fail. 2019 Jun;21(6):792-800. doi: 10.1002/ejhf.1423. Epub 2019 Feb 21.
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571 Cardiac overexpression of melusin protects from dilated cardiomyopathy due to long-standing pressure overload.Circ Res. 2005 May 27;96(10):1087-94. doi: 10.1161/01.RES.0000168028.36081.e0. Epub 2005 Apr 28.
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585 Galectin-3 and fibulin-1 in systolic heart failure - relation to glucose metabolism and left ventricular contractile reserve.BMC Cardiovasc Disord. 2017 Jan 10;17(1):22. doi: 10.1186/s12872-016-0437-6.
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587 Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy.Cell Death Dis. 2019 Nov 26;10(12):890. doi: 10.1038/s41419-019-2121-0.
588 A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.Hum Mol Genet. 2019 Aug 1;28(15):2615-2633. doi: 10.1093/hmg/ddz070.
589 The phenotype of limb-girdle muscular dystrophy type 2I.Neurology. 2003 Apr 22;60(8):1246-51. doi: 10.1212/01.wnl.0000058902.88181.3d.
590 Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure.Nat Commun. 2019 Dec 17;10(1):5754. doi: 10.1038/s41467-019-13623-2.
591 The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling.PLoS One. 2018 Jul 27;13(7):e0201422. doi: 10.1371/journal.pone.0201422. eCollection 2018.
592 Common variants in HSPB7 and FRMD4B associated with advanced heart failure.Circ Cardiovasc Genet. 2010 Apr;3(2):147-54. doi: 10.1161/CIRCGENETICS.109.898395. Epub 2010 Feb 2.
593 Circulating miR-148b-3p and miR-409-3p as biomarkers for heart failure in patients with mitral regurgitation.Int J Cardiol. 2016 Nov 1;222:148-154. doi: 10.1016/j.ijcard.2016.07.179. Epub 2016 Jul 29.
594 The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure.J Intern Med. 2014 Jun;275(6):621-30. doi: 10.1111/joim.12175. Epub 2014 Jan 9.
595 Follistatin-like 1 in Cardiovascular Disease and Inflammation.Mini Rev Med Chem. 2019;19(16):1379-1389. doi: 10.2174/1389557519666190312161551.
596 Binding of FUN14 Domain Containing 1 With Inositol 1,4,5-Trisphosphate Receptor in Mitochondria-Associated Endoplasmic Reticulum Membranes Maintains Mitochondrial Dynamics and Function in Hearts in Vivo.Circulation. 2017 Dec 5;136(23):2248-2266. doi: 10.1161/CIRCULATIONAHA.117.030235. Epub 2017 Sep 23.
597 Effect of Adaptive Servo-Ventilation on Periodic Limb Movements in Sleep in Patients With Heart Failure.Am J Cardiol. 2019 Feb 15;123(4):632-637. doi: 10.1016/j.amjcard.2018.11.014. Epub 2018 Nov 24.
598 Cardiac Gab1 deletion leads to dilated cardiomyopathy associated with mitochondrial damage and cardiomyocyte apoptosis.Cell Death Differ. 2016 Apr;23(4):695-706. doi: 10.1038/cdd.2015.143. Epub 2015 Oct 30.
599 Sympathoexcitation in Rats With Chronic Heart Failure Depends on Homeobox D10 and MicroRNA-7b Inhibiting GABBR1 Translation in Paraventricular Nucleus.Circ Heart Fail. 2016 Jan;9(1):e002261. doi: 10.1161/CIRCHEARTFAILURE.115.002261. Epub 2015 Dec 23.
600 MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts.J Am Heart Assoc. 2017 Feb 10;6(2):e003601. doi: 10.1161/JAHA.116.003601.
601 Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis. Circulation. 2006 Jul 4;114(1 Suppl):I16-20. doi: 10.1161/CIRCULATIONAHA.105.000448.
602 Growth differentiation factor 11 is involved in isoproterenolinduced heart failure.Mol Med Rep. 2019 May;19(5):4109-4118. doi: 10.3892/mmr.2019.10077. Epub 2019 Mar 22.
603 Functional validation of novel MKS3/TMEM67 mutations in COACH syndrome.Sci Rep. 2017 Aug 31;7(1):10222. doi: 10.1038/s41598-017-10652-z.
604 G-protein beta-3 subunit genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine: results of A-HeFT.JACC Heart Fail. 2014 Dec;2(6):551-7. doi: 10.1016/j.jchf.2014.04.016. Epub 2014 Oct 8.
605 Sex- and age-dependent human transcriptome variability: implications for chronic heart failure.Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2754-9. doi: 10.1073/pnas.0436564100. Epub 2003 Feb 24.
606 T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF.Clin Res Cardiol. 2019 Feb;108(2):133-141. doi: 10.1007/s00392-018-1331-2. Epub 2018 Jul 26.
607 Outcomes following implantable cardioverter-defibrillator generator replacement in patients with recovered left ventricular systolic function: The National Cardiovascular Data Registry.Heart Rhythm. 2019 May;16(5):733-740. doi: 10.1016/j.hrthm.2018.11.005. Epub 2018 Nov 7.
608 Cardiac overexpression of the norepinephrine transporter uptake-1 results in marked improvement of heart failure.Circ Res. 2005 Oct 28;97(9):928-36. doi: 10.1161/01.RES.0000186685.46829.E5. Epub 2005 Sep 15.
609 GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A.Am J Physiol Heart Circ Physiol. 2009 Oct;297(4):H1446-52. doi: 10.1152/ajpheart.00513.2009. Epub 2009 Aug 7.
610 Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses.PLoS Genet. 2017 Jul 21;13(7):e1006921. doi: 10.1371/journal.pgen.1006921. eCollection 2017 Jul.
611 Structural impact analysis of missense SNPs present in the uroguanylin gene by long-term molecular dynamics simulations.J Theor Biol. 2016 Dec 7;410:9-17. doi: 10.1016/j.jtbi.2016.09.008. Epub 2016 Sep 9.
612 Uroguanylin: a new actor in the energy balance movie.J Mol Endocrinol. 2018 Feb;60(2):R31-R38. doi: 10.1530/JME-17-0263. Epub 2017 Dec 4.
613 Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure.J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):844-859. doi: 10.1002/jcsm.12322. Epub 2018 Aug 30.
614 HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure.Cardiovasc Res. 2020 Mar 1;116(3):605-618. doi: 10.1093/cvr/cvz182.
615 Successful Treatment of Iron-Overload Cardiomyopathy in Hereditary Hemochromatosis With Deferoxamine and Deferiprone.Can J Cardiol. 2016 Dec;32(12):1574.e1-1574.e3. doi: 10.1016/j.cjca.2016.07.589. Epub 2016 Jul 28.
616 Relationship Between Handgrip Strength and Length of Stay for Left Ventricular Assist Device Implantation.Nutr Clin Pract. 2017 Feb;32(1):98-102. doi: 10.1177/0884533616665926. Epub 2016 Sep 25.
617 Circ-HIPK3 Strengthens the Effects of Adrenaline in Heart Failure by MiR-17-3p - ADCY6 Axis.Int J Biol Sci. 2019 Sep 7;15(11):2484-2496. doi: 10.7150/ijbs.36149. eCollection 2019.
618 The role of 3'-untranslated region (3'-UTR) mediated mRNA stability in cardiovascular pathophysiology.Mol Cell Biochem. 2001 Aug;224(1-2):53-67. doi: 10.1023/a:1011982932645.
619 Homeodomain only protein x is down-regulated in human heart failure.J Mol Cell Cardiol. 2011 Jun;50(6):1056-8. doi: 10.1016/j.yjmcc.2011.02.015. Epub 2011 Mar 5.
620 Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy.Int J Cardiol. 2018 Apr 15;257:283-290. doi: 10.1016/j.ijcard.2017.10.102. Epub 2017 Nov 10.
621 The increased expression of the inducible Hsp70 (HSP70A1A) in serum of patients with heart failure and its protective effect against the cardiotoxic agent doxorubicin.Mol Cell Biochem. 2019 May;455(1-2):41-59. doi: 10.1007/s11010-018-3469-7. Epub 2018 Nov 2.
622 Dynamic adaptation of myocardial proteome during heart failure development.PLoS One. 2017 Oct 3;12(10):e0185915. doi: 10.1371/journal.pone.0185915. eCollection 2017.
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624 Common variants in IL-17A/IL-17RA axis contribute to predisposition to and progression of congestive heart failure.Medicine (Baltimore). 2016 Jul;95(27):e4105. doi: 10.1097/MD.0000000000004105.
625 Interleukin-18 mediates interleukin-1-induced cardiac dysfunction.Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H1025-31. doi: 10.1152/ajpheart.00795.2013. Epub 2014 Feb 14.
626 Interleukin-34 Levels Were Associated with Prognosis in Patients with Acute Myocardial Infarction.Int Heart J. 2019 Nov 30;60(6):1259-1267. doi: 10.1536/ihj.19-111. Epub 2019 Nov 15.
627 Utility and safety of tocilizumab in Takayasu arteritis with severe heart failure and muscle wasting.ESC Heart Fail. 2019 Aug;6(4):894-897. doi: 10.1002/ehf2.12487. Epub 2019 Jul 11.
628 High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles.PLoS One. 2012;7(8):e43340. doi: 10.1371/journal.pone.0043340. Epub 2012 Aug 17.
629 Rationale and design of the IMPACT EU-trial: improve management of heart failure with procalcitonin biomarkers in cardiology (BIC)-18.Biomarkers. 2018 Feb;23(1):97-103. doi: 10.1080/1354750X.2017.1420823. Epub 2018 Jan 8.
630 Relaxin Family Member Insulin-Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models.J Am Heart Assoc. 2018 Jun 10;7(12):e008441. doi: 10.1161/JAHA.117.008441.
631 Risk of Severe Influenza Among Adults With Chronic Medical Conditions.J Infect Dis. 2020 Jan 2;221(2):183-190. doi: 10.1093/infdis/jiz570.
632 Identification of potentially critical genes in the development of heart failure after ST-segment elevation myocardial infarction (STEMI).J Cell Biochem. 2019 May;120(5):7771-7777. doi: 10.1002/jcb.28051. Epub 2018 Nov 28.
633 Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy.Gene. 2013 Jan 10;512(2):206-10. doi: 10.1016/j.gene.2012.10.055. Epub 2012 Nov 1.
634 Catheter Ablation Versus Best Medical Therapy in Patients With Persistent Atrial Fibrillation and Congestive Heart Failure: The Randomized AMICA Trial.Circ Arrhythm Electrophysiol. 2019 Dec;12(12):e007731. doi: 10.1161/CIRCEP.119.007731. Epub 2019 Nov 25.
635 Induction by left ventricular overload and left ventricular failure of the human Jumonji gene (JARID2) encoding a protein that regulates transcription and reexpression of a protective fetal program.J Thorac Cardiovasc Surg. 2008 Sep;136(3):709-16. doi: 10.1016/j.jtcvs.2008.02.020. Epub 2008 Jun 9.
636 JDP2 overexpression provokes cardiac dysfunction in mice.Sci Rep. 2018 May 16;8(1):7647. doi: 10.1038/s41598-018-26052-w.
637 RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6172-6180. doi: 10.1073/pnas.1822176116. Epub 2019 Mar 13.
638 MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.Cell. 2016 Oct 20;167(3):722-738.e23. doi: 10.1016/j.cell.2016.09.052.
639 S38G single-nucleotide polymorphism at the KCNE1 locus is associated with heart failure.Heart Rhythm. 2010 Mar;7(3):363-7. doi: 10.1016/j.hrthm.2009.11.032. Epub 2009 Dec 2.
640 LCZ696 Therapy Reduces Ventricular Tachyarrhythmia Inducibility in a Myocardial Infarction-Induced Heart Failure Rat Model.Cardiovasc Ther. 2019 Jul 1;2019:6032631. doi: 10.1155/2019/6032631. eCollection 2019.
641 Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes.J Clin Invest. 2011 Jul;121(7):2641-50. doi: 10.1172/JCI44641. Epub 2011 Jun 6.
642 Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure.Circ Res. 2019 Jul 19;125(3):265-281. doi: 10.1161/CIRCRESAHA.119.314951. Epub 2019 Jul 18.
643 Cardiac K(2P)13.1 (THIK-1) two-pore-domain K(+) channels: Pharmacological regulation and remodeling in atrial fibrillation.Prog Biophys Mol Biol. 2019 Jul;144:128-138. doi: 10.1016/j.pbiomolbio.2018.06.009. Epub 2018 Jul 6.
644 Increased kielin/chordin-like protein levels are associated with the severity of heart failure.Clin Chim Acta. 2018 Nov;486:381-386. doi: 10.1016/j.cca.2018.08.033. Epub 2018 Aug 23.
645 MiR-147b inhibits cell viability and promotes apoptosis of rat H9c2 cardiomyocytes via down-regulating KLF13 expression.Acta Biochim Biophys Sin (Shanghai). 2018 Mar 1;50(3):288-297. doi: 10.1093/abbs/gmx144.
646 Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.J Clin Invest. 2015 Oct 1;125(10):3819-30. doi: 10.1172/JCI79048. Epub 2015 Sep 14.
647 Multiple roles of KLF15 in the heart: Underlying mechanisms and therapeutic implications.J Mol Cell Cardiol. 2019 Apr;129:193-196. doi: 10.1016/j.yjmcc.2019.01.024. Epub 2019 Mar 2.
648 KLF2 mediates enhanced chemoreflex sensitivity, disordered breathing and autonomic dysregulation in heart failure.J Physiol. 2018 Aug;596(15):3171-3185. doi: 10.1113/JP273805. Epub 2017 Oct 11.
649 Mechanistic Role of Thioredoxin 2 in Heart Failure.Adv Exp Med Biol. 2017;982:265-276. doi: 10.1007/978-3-319-55330-6_14.
650 Assessment of Galectin-3 Polymorphism in Subjects with Chronic Chagas Disease.Arq Bras Cardiol. 2015 Nov;105(5):472-8. doi: 10.5935/abc.20150105. Epub 2015 Aug 25.
651 Left Atrial Dynamics During Exercise in Mitral Regurgitation of Primary and Secondary Origin: Pathophysiological Insights by Exercise Echocardiography Combined With Gas Exchange Analysis.JACC Cardiovasc Imaging. 2020 Jan;13(1 Pt 1):25-40. doi: 10.1016/j.jcmg.2018.12.031. Epub 2019 Mar 13.
652 Cardiac-specific knockout of Lmod2 results in a severe reduction in myofilament force production and rapid cardiac failure.J Mol Cell Cardiol. 2018 Sep;122:88-97. doi: 10.1016/j.yjmcc.2018.08.009. Epub 2018 Aug 11.
653 Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspects.Br J Pharmacol. 2008 Mar;153 Suppl 1(Suppl 1):S414-27. doi: 10.1038/bjp.2008.1. Epub 2008 Feb 4.
654 Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis.Circulation. 2018 Sep 18;138(12):1224-1235. doi: 10.1161/CIRCULATIONAHA.118.035420.
655 LTBP-2 acts as a novel marker in human heart failure - a preliminary study.Biomarkers. 2012 Aug;17(5):407-15. doi: 10.3109/1354750X.2012.677860. Epub 2012 Apr 19.
656 RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.Trends Cardiovasc Med. 2013 Jan;23(1):5-8. doi: 10.1016/j.tcm.2012.08.003. Epub 2012 Aug 31.
657 The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload.Sci Rep. 2019 Jun 24;9(1):9206. doi: 10.1038/s41598-019-45651-9.
658 Exercise training upregulates Nrf2 protein in the rostral ventrolateral medulla of mice with heart failure.J Appl Physiol (1985). 2019 Nov 1;127(5):1349-1359. doi: 10.1152/japplphysiol.00469.2019. Epub 2019 Sep 26.
659 Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community.J Am Heart Assoc. 2017 Aug 3;6(8):e006028. doi: 10.1161/JAHA.117.006028.
660 RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.J Clin Invest. 2014 Aug;124(8):3419-30. doi: 10.1172/JCI74523. Epub 2014 Jun 24.
661 Early Postdischarge STOP-HF-Clinic Reduces 30-day Readmissions in Old and Frail Patients With Heart Failure.Rev Esp Cardiol (Engl Ed). 2017 Aug;70(8):631-638. doi: 10.1016/j.rec.2017.01.003. Epub 2017 Feb 16.
662 Hemodynamic Assessment of Patients With and Without Heart Failure Symptoms Supported by a Continuous-Flow Left Ventricular Assist Device.Mayo Clin Proc. 2018 Jul;93(7):895-903. doi: 10.1016/j.mayocp.2018.01.031. Epub 2018 Jun 19.
663 Can Functional Testing for Ischemia and Viability Guide Revascularization?.JACC Cardiovasc Imaging. 2017 Mar;10(3):354-364. doi: 10.1016/j.jcmg.2016.12.011.
664 The challenge of cardiomyopathies and heart failure in pregnancy.Curr Opin Obstet Gynecol. 2018 Dec;30(6):378-384. doi: 10.1097/GCO.0000000000000496.
665 Porous Hydrogel-Encapsulated Photonic Barcodes for Multiplex Detection of Cardiovascular Biomarkers.ACS Sens. 2019 May 24;4(5):1384-1390. doi: 10.1021/acssensors.9b00352. Epub 2019 Apr 19.
666 Heart Failure and Cognitive Impairment in the Atherosclerosis Risk in Communities (ARIC) Study.J Gen Intern Med. 2018 Oct;33(10):1721-1728. doi: 10.1007/s11606-018-4556-x. Epub 2018 Jul 20.
667 Mitochondrial calcium uniporter inhibition provides cardioprotection in pressure overload-induced heart failure through autophagy enhancement.Int J Cardiol. 2018 Nov 15;271:161-168. doi: 10.1016/j.ijcard.2018.05.054. Epub 2018 May 20.
668 Effect of 6 wk of high-intensity one-legged cycling on functional sympatholysis and ATP signaling in patients with heart failure.Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H616-H626. doi: 10.1152/ajpheart.00379.2017. Epub 2017 Nov 22.
669 Adriamycin induced myocardial failure in rats: protective role of Centella asiatica.Mol Cell Biochem. 2007 Jan;294(1-2):55-63. doi: 10.1007/s11010-006-9245-0. Epub 2006 Jun 20.
670 Downregulation of myocardial myocyte enhancer factor 2C and myocyte enhancer factor 2C-regulated gene expression in diabetic patients with nonischemic heart failure.Circulation. 2002 Jul 23;106(4):407-11. doi: 10.1161/01.cir.0000026392.80723.dc.
671 Meox1 accelerates myocardial hypertrophic decompensation through Gata4.Cardiovasc Res. 2018 Feb 1;114(2):300-311. doi: 10.1093/cvr/cvx222.
672 The N(6)-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy.Circulation. 2019 Jan 22;139(4):533-545. doi: 10.1161/CIRCULATIONAHA.118.036146.
673 Mitochondrial Dynamics in Tachycardiomyopathy.Cell Physiol Biochem. 2019;52(3):435-438. doi: 10.33594/000000031. Epub 2019 Mar 15.
674 Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.Front Physiol. 2019 Apr 10;10:382. doi: 10.3389/fphys.2019.00382. eCollection 2019.
675 Daily Supplementation with 4000 IU Vitamin D3 for Three Years Does Not Modify Cardiovascular Risk Markers in Patients with Advanced Heart Failure: The Effect of Vitamin D on Mortality in Heart Failure Trial.Ann Nutr Metab. 2019;74(1):62-68. doi: 10.1159/000495662. Epub 2018 Dec 14.
676 Macrophage inflammatory protein-1alpha C-C chemokine in parapneumonic pleural effusions.J Lab Clin Med. 1998 Sep;132(3):202-9. doi: 10.1016/s0022-2143(98)90169-x.
677 Depressed Myocardial Energetic Efficiency Increases Risk of Incident Heart Failure: The Strong Heart Study.J Clin Med. 2019 Jul 17;8(7):1044. doi: 10.3390/jcm8071044.
678 Analysis of necroptotic proteins in failing human hearts.J Transl Med. 2017 Apr 28;15(1):86. doi: 10.1186/s12967-017-1189-5.
679 Potential roles of circulating matrix metalloproteinase-28 (MMP-28) in patients with atrial fibrillation.Life Sci. 2018 Jul 1;204:15-19. doi: 10.1016/j.lfs.2018.04.053. Epub 2018 May 2.
680 SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity.Circ Res. 2017 Jan 6;120(1):110-119. doi: 10.1161/CIRCRESAHA.116.309977. Epub 2016 Oct 11.
681 Third Annual Report From the ISHLT Mechanically Assisted Circulatory Support Registry: A comparison of centrifugal and axial continuous-flow left ventricular assist devices.J Heart Lung Transplant. 2019 Apr;38(4):352-363. doi: 10.1016/j.healun.2019.02.004.
682 The different roles for the advanced glycation end products axis in heart failure and acute coronary syndrome settings.Nutr Metab Cardiovasc Dis. 2019 Oct;29(10):1050-1060. doi: 10.1016/j.numecd.2019.06.014. Epub 2019 Jun 22.
683 Mon2 predicts poor outcome in ST-elevation myocardial infarction.J Intern Med. 2019 Mar;285(3):301-316. doi: 10.1111/joim.12847. Epub 2019 Jan 15.
684 Utility of nuclear stress imaging in predicting long-term outcomes one-year post CABG Surgery.J Nucl Cardiol. 2020 Dec;27(6):1970-1978. doi: 10.1007/s12350-018-01469-y. Epub 2018 Nov 5.
685 A common variant of RIP3 promoter region is associated with poor prognosis in heart failure patients by influencing SOX17 binding.J Cell Mol Med. 2019 Aug;23(8):5317-5328. doi: 10.1111/jcmm.14408. Epub 2019 May 31.
686 Mst1 knockout enhances cardiomyocyte autophagic flux to alleviate angiotensin II-induced cardiac injury independent of angiotensin II receptors.J Mol Cell Cardiol. 2018 Dec;125:117-128. doi: 10.1016/j.yjmcc.2018.08.028. Epub 2018 Sep 5.
687 G Protein-Coupled Receptor-G-Protein -Subunit Signaling Mediates Renal Dysfunction and Fibrosis in Heart Failure.J Am Soc Nephrol. 2017 Jan;28(1):197-208. doi: 10.1681/ASN.2015080852. Epub 2016 Jun 13.
688 Novel role of mitochondrial GTPases 1 in pathological cardiac hypertrophy.J Mol Cell Cardiol. 2019 Mar;128:105-116. doi: 10.1016/j.yjmcc.2019.01.025. Epub 2019 Jan 29.
689 Skeletal Muscle Resident Progenitor Cells Coexpress Mesenchymal and Myogenic Markers and Are Not Affected by Chronic Heart Failure-Induced Dysregulations.Stem Cells Int. 2019 Jan 3;2019:5690345. doi: 10.1155/2019/5690345. eCollection 2019.
690 Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expression.PLoS One. 2009;4(4):e5144. doi: 10.1371/journal.pone.0005144. Epub 2009 Apr 9.
691 Control of p21Cip by BRCA1-associated protein is critical for cardiomyocyte cell cycle progression and survival.Cardiovasc Res. 2020 Mar 1;116(3):592-604. doi: 10.1093/cvr/cvz177.
692 Generation of MLC-2v-tdTomato knock-in reporter mouse line.Genesis. 2018 Oct;56(10):e23256. doi: 10.1002/dvg.23256. Epub 2018 Nov 2.
693 Long-term outcome of 4 Korean families with hypertrophic cardiomyopathy caused by 4 different mutations.Clin Cardiol. 2010 Jul;33(7):430-8. doi: 10.1002/clc.20795.
694 Human atrial myosin light chain 1 expression attenuates heart failure.Adv Exp Med Biol. 2005;565:283-92; discussion 92, 405-15. doi: 10.1007/0-387-24990-7_21.
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696 YiQiFuMai powder injection ameliorates chronic heart failure through cross-talk between adipose tissue and cardiomyocytes via up-regulation of circulating adipokine omentin.Biomed Pharmacother. 2019 Nov;119:109418. doi: 10.1016/j.biopha.2019.109418. Epub 2019 Sep 7.
697 Myocardin mRNA is augmented in the failing myocardium: expression profiling in the porcine model and human dilated cardiomyopathy.J Mol Med (Berl). 2003 Sep;81(9):566-77. doi: 10.1007/s00109-003-0470-7. Epub 2003 Aug 13.
698 Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110. doi: 10.1073/pnas.1719309115. Epub 2018 Apr 9.
699 Inducible nitric oxide synthase in skeletal muscle of patients with chronic heart failure.J Am Coll Cardiol. 1998 Oct;32(4):964-9. doi: 10.1016/s0735-1097(98)00335-0.
700 Impact of sacubitril-valsartan combination in patients with chronic heart failure and sleep apnoea syndrome: the ENTRESTO-SAS study design.ESC Heart Fail. 2018 Jun;5(3):222-230. doi: 10.1002/ehf2.12270. Epub 2018 Feb 22.
701 NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly.Cell Res. 2019 Sep;29(9):754-766. doi: 10.1038/s41422-019-0208-x. Epub 2019 Jul 31.
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703 Differences in MEF2 and NFAT transcriptional pathways according to human heart failure aetiology.PLoS One. 2012;7(2):e30915. doi: 10.1371/journal.pone.0030915. Epub 2012 Feb 17.
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706 Renal and Cardiovascular Effects of sodium-glucose cotransporter 2 (SGLT2) inhibition in combination with loop Diuretics in diabetic patients with Chronic Heart Failure (RECEDE-CHF): protocol for a randomised controlled double-blind cross-over trial.BMJ Open. 2017 Oct 16;7(10):e018097. doi: 10.1136/bmjopen-2017-018097.
707 Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart.PLoS One. 2016 Oct 20;11(10):e0164897. doi: 10.1371/journal.pone.0164897. eCollection 2016.
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709 High- Versus Low-Gradient Severe Aortic Stenosis: Demographics, Clinical Outcomes, and Effects of the Initial Aortic Valve Replacement Strategy on Long-Term Prognosis.Circ Cardiovasc Interv. 2017 May;10(5):e004796. doi: 10.1161/CIRCINTERVENTIONS.116.004796.
710 Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.Circulation. 2017 Feb 28;135(9):881-897. doi: 10.1161/CIRCULATIONAHA.116.022852. Epub 2016 Dec 7.
711 A common NOS1AP genetic polymorphism, rs12567209 G>A, is associated with sudden cardiac death in patients with chronic heart failure in the Chinese Han population.J Card Fail. 2014 Apr;20(4):244-51. doi: 10.1016/j.cardfail.2014.01.006. Epub 2014 Jan 10.
712 Increase of NADPH oxidase 3 in heart failure of hereditary cardiomyopathy (1).Can J Physiol Pharmacol. 2019 Sep;97(9):902-908. doi: 10.1139/cjpp-2019-0055. Epub 2019 Mar 21.
713 Cardiac safety of adjuvant non-pegylated liposomal doxorubicin combined with cyclophosphamide and followed by paclitaxel in older breast cancer patients.Breast. 2017 Feb;31:186-191. doi: 10.1016/j.breast.2016.11.006. Epub 2016 Nov 23.
714 Association Between Plasma Brain Natriuretic Peptide and Overall Survival in Patients With Advanced Cancer: Preliminary Findings.J Pain Symptom Manage. 2019 Sep;58(3):465-471. doi: 10.1016/j.jpainsymman.2019.05.006. Epub 2019 May 22.
715 Receptor-interacting protein 140 overexpression impairs cardiac mitochondrial function and accelerates the transition to heart failure in chronically infarcted rats.Transl Res. 2017 Feb;180:91-102.e1. doi: 10.1016/j.trsl.2016.08.005. Epub 2016 Aug 31.
716 Wolf-Hirschhorn Syndrome Candidate 1 (whsc1) Functions as a Tumor Suppressor by Governing Cell Differentiation.Neoplasia. 2017 Aug;19(8):606-616. doi: 10.1016/j.neo.2017.05.001. Epub 2017 Jun 24.
717 A novel activator of C-C chemokine, FROUNT, is expressed with C-C chemokine receptor 2 and its ligand in failing human heart.J Card Fail. 2007 Mar;13(2):114-9. doi: 10.1016/j.cardfail.2006.11.003.
718 MicroRNA-539 is up-regulated in failing heart, and suppresses O-GlcNAcase expression.J Biol Chem. 2014 Oct 24;289(43):29665-76. doi: 10.1074/jbc.M114.578682. Epub 2014 Sep 2.
719 Osteoglycin prevents cardiac dilatation and dysfunction after myocardial infarction through infarct collagen strengthening.Circ Res. 2015 Jan 30;116(3):425-36. doi: 10.1161/CIRCRESAHA.116.304599. Epub 2014 Dec 17.
720 Ablation of the stress protease OMA1 protects against heart failure in mice.Sci Transl Med. 2018 Mar 28;10(434):eaan4935. doi: 10.1126/scitranslmed.aan4935.
721 Cardiac inflammatory CD11b/c cells exert a protective role in hypertrophied cardiomyocyte by promoting TNFR(2)- and Orai3- dependent signaling.Sci Rep. 2019 Apr 15;9(1):6047. doi: 10.1038/s41598-019-42452-y.
722 Structural and myocardial dysfunction in heart failure beyond ejection fraction.Heart Fail Rev. 2020 Jan;25(1):9-17. doi: 10.1007/s10741-019-09828-8.
723 A New Secretory Peptide of Natriuretic Peptide Family, Osteocrin, Suppresses the Progression of Congestive Heart Failure After Myocardial Infarction.Circ Res. 2018 Mar 2;122(5):742-751. doi: 10.1161/CIRCRESAHA.117.312624. Epub 2018 Jan 11.
724 Pregnancy-associated plasma protein-A (PAPP-A) and the proform of the eosinophil major basic protein (ProMBP) are associated with increased risk of death in heart failure patients.Scand J Clin Lab Invest. 2017 Sep;77(5):352-357. doi: 10.1080/00365513.2017.1325926. Epub 2017 May 24.
725 PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism.Int J Mol Sci. 2018 May 16;19(5):1485. doi: 10.3390/ijms19051485.
726 Effects of two Gbetagamma-binding proteins--N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus (betaARKct)--in heart failure.Gene Ther. 2003 Aug;10(16):1354-61. doi: 10.1038/sj.gt.3301995.
727 The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells.PLoS One. 2011;6(5):e19724. doi: 10.1371/journal.pone.0019724. Epub 2011 May 23.
728 Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.PLoS One. 2009;4(5):e5232. doi: 10.1371/journal.pone.0005232. Epub 2009 May 1.
729 Adrenergic Regulation of Drp1-Driven Mitochondrial Fission in Cardiac Physio-Pathology.Antioxidants (Basel). 2018 Dec 18;7(12):195. doi: 10.3390/antiox7120195.
730 Proenkephalin and prognosis in heart failure with preserved ejection fraction: a GREAT network study.Clin Res Cardiol. 2019 Aug;108(8):940-949. doi: 10.1007/s00392-019-01424-y. Epub 2019 Feb 14.
731 Profilin? contributes to cardiac injury induced by advanced glycation endproducts in rats.Mol Med Rep. 2017 Nov;16(5):6634-6641. doi: 10.3892/mmr.2017.7446. Epub 2017 Sep 8.
732 Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies.BMC Mol Biol. 2010 Mar 23;11:22. doi: 10.1186/1471-2199-11-22.
733 Novel Role for Pleckstrin Homology-Like Domain Family A, Member 3 in the Regulation of Pathological Cardiac Hypertrophy.J Am Heart Assoc. 2019 Aug 20;8(16):e011830. doi: 10.1161/JAHA.118.011830. Epub 2019 Aug 20.
734 Multiple faces of protein interacting with C kinase 1 (PICK1): Structure, function, and diseases.Neurochem Int. 2016 Sep;98:115-21. doi: 10.1016/j.neuint.2016.03.001. Epub 2016 Mar 9.
735 Stretch-activated channel Piezo1 is up-regulated in failure heart and cardiomyocyte stimulated by AngII.Am J Transl Res. 2017 Jun 15;9(6):2945-2955. eCollection 2017.
736 AMPK2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation.Circ Res. 2018 Mar 2;122(5):712-729. doi: 10.1161/CIRCRESAHA.117.312317. Epub 2017 Dec 28.
737 Assessing inflammation in Chinese subjects with subtypes of heart failure: an observational study of the Chinese PLA Hospital Heart Failure Registry.J Geriatr Cardiol. 2019 Apr;16(4):313-319. doi: 10.11909/j.issn.1671-5411.2019.04.002.
738 Protein kinase D isoforms are activated in an agonist-specific manner in cardiomyocytes.J Biol Chem. 2011 Feb 25;286(8):6500-9. doi: 10.1074/jbc.M110.208058. Epub 2010 Dec 14.
739 Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy.J Mol Cell Cardiol. 2013 May;58:199-208. doi: 10.1016/j.yjmcc.2013.01.015. Epub 2013 Jan 30.
740 Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium.J Hepatol. 2019 Jul;71(1):143-152. doi: 10.1016/j.jhep.2019.02.024. Epub 2019 Mar 19.
741 Recessive variants in plakophilin-2 contributes to early-onset arrhythmogenic cardiomyopathy with severe heart failure.Europace. 2019 Jun 1;21(6):970-977. doi: 10.1093/europace/euz026.
742 Association of CKIP-1 P21A polymorphism with risk of chronic heart failure in a Chinese population.Oncotarget. 2017 May 30;8(22):36545-36552. doi: 10.18632/oncotarget.16614.
743 Plin5 deficiency exacerbates pressure overload-induced cardiac hypertrophy and heart failure by enhancing myocardial fatty acid oxidation and oxidative stress.Free Radic Biol Med. 2019 Sep;141:372-382. doi: 10.1016/j.freeradbiomed.2019.07.006. Epub 2019 Jul 7.
744 Cardiac-specific inactivation of LPP3 in mice leads to myocardial dysfunction and heart failure.Redox Biol. 2018 Apr;14:261-271. doi: 10.1016/j.redox.2017.09.015. Epub 2017 Sep 28.
745 The lncRNA Plscr4 Controls Cardiac Hypertrophy by Regulating miR-214.Mol Ther Nucleic Acids. 2018 Mar 2;10:387-397. doi: 10.1016/j.omtn.2017.12.018. Epub 2017 Dec 30.
746 Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.PLoS Genet. 2018 Jan 10;14(1):e1007171. doi: 10.1371/journal.pgen.1007171. eCollection 2018 Jan.
747 Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.Nat Commun. 2017 Sep 18;8(1):578. doi: 10.1038/s41467-017-00654-w.
748 Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1 (Peroxisome Proliferator-Activated Receptor- Coactivator-1) Dysregulation.Circ Heart Fail. 2019 Mar;12(3):e005529. doi: 10.1161/CIRCHEARTFAILURE.118.005529.
749 -Thromboglobulin and incident cardiovascular disease risk: The Atherosclerosis Risk in Communities study.Thromb Res. 2017 Jul;155:116-120. doi: 10.1016/j.thromres.2017.05.016. Epub 2017 May 17.
750 Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure.Curr Drug Metab. 2008 Feb;9(2):122-8. doi: 10.2174/138920008783571792.
751 Catabolism of branched-chain amino acids in heart failure: insights from genetic models.Pediatr Cardiol. 2011 Mar;32(3):305-10. doi: 10.1007/s00246-010-9856-9. Epub 2011 Jan 7.
752 Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.Circulation. 2018 Oct 9;138(15):1569-1581. doi: 10.1161/CIRCULATIONAHA.118.034361.
753 Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure.Nat Commun. 2019 Jun 24;10(1):2760. doi: 10.1038/s41467-019-10591-5.
754 PR65A phosphorylation regulates PP2A complex signaling.PLoS One. 2014 Jan 21;9(1):e85000. doi: 10.1371/journal.pone.0085000. eCollection 2014.
755 NT-proBNP (N-Terminal pro-B-Type Natriuretic Peptide)-Guided Therapy in Acute Decompensated Heart Failure: PRIMA II Randomized Controlled Trial (Can NT-ProBNP-Guided Therapy During Hospital Admission for Acute Decompensated Heart Failure Reduce Mortality and Readmissions?).Circulation. 2018 Apr 17;137(16):1671-1683. doi: 10.1161/CIRCULATIONAHA.117.029882. Epub 2017 Dec 14.
756 BDNF contributes to the skeletal muscle anti-atrophic effect of exercise training through AMPK-PGC1 signaling in heart failure mice.Arch Med Sci. 2019 Jan;15(1):214-222. doi: 10.5114/aoms.2018.81037. Epub 2018 Dec 30.
757 Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure.PLoS One. 2013 May 31;8(5):e64603. doi: 10.1371/journal.pone.0064603. Print 2013.
758 Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.J Biol Chem. 2003 Nov 7;278(45):44935-48. doi: 10.1074/jbc.M307696200. Epub 2003 Aug 21.
759 Protein kinase C regulates internal initiation of translation of the GATA-4 mRNA following vasopressin-induced hypertrophy of cardiac myocytes.J Biol Chem. 2007 Mar 30;282(13):9505-9516. doi: 10.1074/jbc.M608874200. Epub 2007 Feb 6.
760 Increased myocardial Rab GTPase expression: a consequence and cause of cardiomyopathy.Circ Res. 2001 Dec 7;89(12):1130-7. doi: 10.1161/hh2401.100427.
761 Genetic susceptibility to anthracycline-related congestive heart failure in survivors of haematopoietic cell transplantation.Br J Haematol. 2013 Oct;163(2):205-13. doi: 10.1111/bjh.12516. Epub 2013 Aug 8.
762 Brain Natriuretic Peptide mediates the prognostic role of renal function toward 10-year cardiovascular mortality in patients with Acute Coronary Syndrome: the HHF study (2006-2016).Hellenic J Cardiol. 2018 Mar-Apr;59(2):110-118. doi: 10.1016/j.hjc.2017.07.001. Epub 2017 Jul 13.
763 Serum Chemerin as a Novel Prognostic Indicator in Chronic Heart Failure.J Am Heart Assoc. 2019 Aug 6;8(15):e012091. doi: 10.1161/JAHA.119.012091. Epub 2019 Jul 23.
764 Significance of the CAPRI risk score to predict heart failure hospitalization post-TAVI: The CAPRI-HF study.Int J Cardiol. 2019 Dec 1;296:98-102. doi: 10.1016/j.ijcard.2019.08.033. Epub 2019 Aug 19.
765 A Splicing-Independent Function of RBM10 Controls Specific 3' UTR Processing to Regulate Cardiac Hypertrophy.Cell Rep. 2018 Sep 25;24(13):3539-3553. doi: 10.1016/j.celrep.2018.08.077.
766 Splicing Factor RBM20 Regulates Transcriptional Network of Titin Associated and Calcium Handling Genes in The Heart.Int J Biol Sci. 2018 Mar 9;14(4):369-380. doi: 10.7150/ijbs.24117. eCollection 2018.
767 RNA binding protein 24 deletion disrupts global alternative splicing and causes dilated cardiomyopathy.Protein Cell. 2019 Jun;10(6):405-416. doi: 10.1007/s13238-018-0578-8. Epub 2018 Sep 28.
768 Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure.Circulation. 2011 Sep 6;124(10):1124-31. doi: 10.1161/CIRCULATIONAHA.111.044495. Epub 2011 Aug 22.
769 Identification of circulating placental mRNA in maternal blood of pregnancies affected with fetal congenital heart diseases at the second trimester of pregnancy: implications for early molecular screening.Prenat Diagn. 2010 Mar;30(3):229-34. doi: 10.1002/pd.2443.
770 REEP5 (Receptor Accessory Protein 5) Acts as a Sarcoplasmic Reticulum Membrane Sculptor to Modulate Cardiac Function.J Am Heart Assoc. 2018 Feb 3;7(3):e007205. doi: 10.1161/JAHA.117.007205.
771 Is there a relationship between resistin levels and left ventricular end-diastolic pressure?.Anatol J Cardiol. 2018 Apr;19(4):267-272. doi: 10.14744/AnatolJCardiol.2018.66181.
772 Pathophysiological effects of RhoA and Rho-associated kinase on cardiovascular system.J Hypertens. 2016 Jan;34(1):3-10. doi: 10.1097/HJH.0000000000000768.
773 RNA-sequencing analysis reveals new alterations in cardiomyocyte cytoskeletal genes in patients with heart failure.Lab Invest. 2014 Jun;94(6):645-53. doi: 10.1038/labinvest.2014.54. Epub 2014 Apr 7.
774 The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.Nat Med. 2017 Oct;23(10):1215-1219. doi: 10.1038/nm.4393. Epub 2017 Aug 28.
775 Ultrastructure and regulation of lateralized connexin43 in the failing heart.Circ Res. 2010 Apr 2;106(6):1153-63. doi: 10.1161/CIRCRESAHA.108.182147. Epub 2010 Feb 18.
776 Rnd3/RhoE Modulates Hypoxia-Inducible Factor 1/Vascular Endothelial Growth Factor Signaling by Stabilizing Hypoxia-Inducible Factor 1 and Regulates Responsive Cardiac Angiogenesis.Hypertension. 2016 Mar;67(3):597-605. doi: 10.1161/HYPERTENSIONAHA.115.06412. Epub 2016 Jan 18.
777 Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart.Circ Res. 1994 Feb;74(2):206-13. doi: 10.1161/01.res.74.2.206.
778 Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart.J Cardiovasc Transl Res. 2016 Dec;9(5-6):432-444. doi: 10.1007/s12265-016-9716-y. Epub 2016 Oct 31.
779 RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment.Pharmacogenomics J. 2013 Aug;13(4):330-4. doi: 10.1038/tpj.2012.22. Epub 2012 Jun 5.
780 Relationship of stroke volume to different patterns of Cheyne-Stokes respiration in heart failure.Sleep. 2019 Apr 1;42(4):zsy262. doi: 10.1093/sleep/zsy262.
781 Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy.J Exp Med. 2007 May 14;204(5):1227-35. doi: 10.1084/jem.20070145. Epub 2007 May 7.
782 Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties.PLoS One. 2012;7(5):e37401. doi: 10.1371/journal.pone.0037401. Epub 2012 May 24.
783 Short-Term Effects of Tolvaptan in PatientsWith Acute Heart Failure andVolume Overload.J Am Coll Cardiol. 2017 Mar 21;69(11):1409-1419. doi: 10.1016/j.jacc.2016.12.035.
784 Syndecan-4 deficiency accelerates the transition from compensated hypertrophy to heart failure following pressure overload.Cardiovasc Pathol. 2017 May-Jun;28:74-79. doi: 10.1016/j.carpath.2017.03.008. Epub 2017 Mar 30.
785 In-hospital outcomes of delayed stenting in hemodynamically stable patients with ST-segment elevation myocardial infarction: the CCC (Care for Cardiovascular Disease in China) project.Cardiovasc Diagn Ther. 2019 Oct;9(5):462-471. doi: 10.21037/cdt.2019.08.10.
786 Immature surfactant protein-B impairs the antioxidant capacity of HDL.Int J Cardiol. 2019 Jun 15;285:53-58. doi: 10.1016/j.ijcard.2019.02.057. Epub 2019 Feb 27.
787 SLMAP-3 is downregulated in human dilated ventricles and its overexpression promotes cardiomyocyte response to adrenergic stimuli by increasing intracellular calcium.Can J Physiol Pharmacol. 2019 Jul;97(7):623-630. doi: 10.1139/cjpp-2018-0660. Epub 2019 Mar 11.
788 Decreased sarcolipin protein expression and enhanced sarco(endo)plasmic reticulum Ca2+ uptake in human atrial fibrillation.Biochem Biophys Res Commun. 2011 Jun 24;410(1):97-101. doi: 10.1016/j.bbrc.2011.05.113. Epub 2011 May 25.
789 Heart Transplantation from Biventricular Support in Infant with Novel SMYD1 Mutation.Pediatr Cardiol. 2019 Dec;40(8):1745-1747. doi: 10.1007/s00246-019-02139-7. Epub 2019 Jul 5.
790 Genetically Low Antioxidant Protection and Risk of Cardiovascular Disease and Heart Failure in Diabetic Subjects.EBioMedicine. 2015 Nov 14;2(12):2010-5. doi: 10.1016/j.ebiom.2015.11.026. eCollection 2015 Dec.
791 Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3436-E3445. doi: 10.1073/pnas.1717423115. Epub 2018 Mar 26.
792 Defining new mechanistic roles for II spectrin in cardiac function.J Biol Chem. 2019 Jun 14;294(24):9576-9591. doi: 10.1074/jbc.RA119.007714. Epub 2019 May 7.
793 Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction.Dis Model Mech. 2012 Jul;5(4):481-91. doi: 10.1242/dmm.009456. Epub 2012 Apr 5.
794 miR-1 mediated suppression of Sorcin regulates myocardial contractility through modulation of Ca2+ signaling.J Mol Cell Cardiol. 2012 May;52(5):1027-37. doi: 10.1016/j.yjmcc.2012.01.020. Epub 2012 Feb 4.
795 Food groups and risk of coronary heart disease, stroke and heart failure: A systematic review and dose-response meta-analysis of prospective studies.Crit Rev Food Sci Nutr. 2019;59(7):1071-1090. doi: 10.1080/10408398.2017.1392288. Epub 2017 Nov 7.
796 Enhanced store-operated Ca(2+) influx and ORAI1 expression in ventricular fibroblasts from human failing heart.Biol Open. 2017 Mar 15;6(3):326-332. doi: 10.1242/bio.022632.
797 The SLMAP/Striatin complex: An emerging regulator of normal and abnormal cardiac excitation-contraction coupling.Eur J Pharmacol. 2019 Sep 5;858:172491. doi: 10.1016/j.ejphar.2019.172491. Epub 2019 Jun 21.
798 Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure.JAMA Cardiol. 2019 Jan 1;4(1):25-33. doi: 10.1001/jamacardio.2018.3965.
799 Mineralocorticoid receptor antagonists in patients with heart failure: current experience and future perspectives.Eur Heart J Cardiovasc Pharmacother. 2017 Jan;3(1):48-57. doi: 10.1093/ehjcvp/pvw016. Epub 2016 Aug 2.
800 miR-146a Suppresses SUMO1 Expression and Induces Cardiac Dysfunction in Maladaptive Hypertrophy.Circ Res. 2018 Aug 31;123(6):673-685. doi: 10.1161/CIRCRESAHA.118.312751.
801 SUMOylation in cardiac disorders - a review.Eur Rev Med Pharmacol Sci. 2017 Apr;21(7):1583-1587.
802 Involvement of activated SUMO-2 conjugation in cardiomyopathy.Biochim Biophys Acta. 2015 Jul;1852(7):1388-99. doi: 10.1016/j.bbadis.2015.03.013. Epub 2015 Apr 6.
803 Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure.PLoS One. 2018 Aug 20;13(8):e0201160. doi: 10.1371/journal.pone.0201160. eCollection 2018.
804 Mitsugumin 29 regulates t-tubule architecture in the failing heart.Sci Rep. 2017 Jul 13;7(1):5328. doi: 10.1038/s41598-017-05284-2.
805 Electrophysiologic and anatomic factors predictive of a need for touch-up radiofrequency application for complete pulmonary vein isolation: Comparison between hot balloon- and cryoballoon-based ablation.J Cardiovasc Electrophysiol. 2019 Aug;30(8):1261-1269. doi: 10.1111/jce.13989. Epub 2019 Jun 11.
806 Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury.Circ Res. 2010 Jun 11;106(11):1692-702. doi: 10.1161/CIRCRESAHA.109.214346. Epub 2010 Apr 22.
807 TFAM overexpression reduces pathological cardiac remodeling.Mol Cell Biochem. 2019 Apr;454(1-2):139-152. doi: 10.1007/s11010-018-3459-9. Epub 2018 Oct 23.
808 Highly Dynamic Changes in the Activity and Regulation of Macroautophagy in Hearts Subjected to Increased Proteotoxic Stress.Front Physiol. 2019 Jun 26;10:758. doi: 10.3389/fphys.2019.00758. eCollection 2019.
809 Diferric transferrin regulates transferrin receptor 2 protein stability.Blood. 2004 Dec 15;104(13):4287-93. doi: 10.1182/blood-2004-06-2477. Epub 2004 Aug 19.
810 Translocase of Inner Membrane 50 Functions as a Novel Protective Regulator of Pathological Cardiac Hypertrophy.J Am Heart Assoc. 2017 Apr 21;6(4):e004346. doi: 10.1161/JAHA.116.004346.
811 Efficacy and safety of DPP-4 inhibitors in patients with type 2 diabetes: Meta-analysis of placebo-controlled randomized clinical trials.Diabetes Metab. 2017 Feb;43(1):48-58. doi: 10.1016/j.diabet.2016.09.005. Epub 2016 Oct 10.
812 Analyses of long non-coding RNA and mRNA profiles in right ventricle myocardium of acute right heart failure in pulmonary arterial hypertension rats.Biomed Pharmacother. 2018 Oct;106:1108-1115. doi: 10.1016/j.biopha.2018.07.057. Epub 2018 Jul 17.
813 Sensitivity analysis revealing the effect of modulating ionic mechanisms on calcium dynamics in simulated human heart failure.PLoS One. 2017 Nov 8;12(11):e0187739. doi: 10.1371/journal.pone.0187739. eCollection 2017.
814 Targeting Transmembrane BAX Inhibitor Motif Containing 1 Alleviates Pathological Cardiac Hypertrophy.Circulation. 2018 Apr 3;137(14):1486-1504. doi: 10.1161/CIRCULATIONAHA.117.031659. Epub 2017 Dec 11.
815 Dysregulated Zn(2+) homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca(2+) leakage.J Biol Chem. 2017 Aug 11;292(32):13361-13373. doi: 10.1074/jbc.M117.781708. Epub 2017 Jun 19.
816 TOR1AIP1 as a cause of cardiac failure and recessive limb-girdle muscular dystrophy.Neuromuscul Disord. 2016 Aug;26(8):500-3. doi: 10.1016/j.nmd.2016.05.013. Epub 2016 May 24.
817 Ebstein anomaly, left ventricular non-compaction, and early onset heart failure associated with a de novo -tropomyosin gene mutation.Am J Med Genet A. 2016 Aug;170(8):2186-90. doi: 10.1002/ajmg.a.37745. Epub 2016 May 13.
818 Cardioprotective Role of Tumor Necrosis Factor Receptor-Associated Factor 2 by Suppressing Apoptosis and Necroptosis.Circulation. 2017 Aug 22;136(8):729-742. doi: 10.1161/CIRCULATIONAHA.116.026240. Epub 2017 Jun 1.
819 Tripartite motif 32 prevents pathological cardiac hypertrophy.Clin Sci (Lond). 2016 May 1;130(10):813-28. doi: 10.1042/CS20150619. Epub 2016 Feb 16.
820 Small-molecule-mediated chemical knock-down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure.J Cachexia Sarcopenia Muscle. 2019 Oct;10(5):1102-1115. doi: 10.1002/jcsm.12448. Epub 2019 May 29.
821 Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding.PLoS One. 2014 Mar 3;9(3):e89621. doi: 10.1371/journal.pone.0089621. eCollection 2014.
822 Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, -adrenergic insensitivity, and increased apoptosis.J Cell Physiol. 2018 Sep;233(9):6319-6326. doi: 10.1002/jcp.26482. Epub 2018 Mar 30.
823 [Salubrinal improves cardiac function in rats with heart failure post myocardial infarction through reducing endoplasmic reticulum stress-associated apoptosis].Zhonghua Xin Xue Guan Bing Za Zhi. 2016 Jun 24;44(6):494-500. doi: 10.3760/cma.j.issn.0253-3758.2016.06.008.
824 Response of caspase-independent apoptotic factors to high salt diet-induced heart failure.J Mol Cell Cardiol. 2007 Mar;42(3):678-86. doi: 10.1016/j.yjmcc.2007.01.001. Epub 2007 Jan 9.
825 Down-regulation of FKBP12.6 and SERCA2a contributes to acute heart failure in septic shock and is related to an up-regulated endothelin signalling pathway.J Pharm Pharmacol. 2007 Jul;59(7):977-84. doi: 10.1211/jpp.59.7.0010.
826 Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.Circ Res. 2002 Nov 29;91(11):1056-62. doi: 10.1161/01.res.0000045088.59360.b7.
827 Cardiac Involvement in Emery-Dreifuss Muscular Dystrophy and Related Management Strategies.Int Heart J. 2019 Jan 25;60(1):12-18. doi: 10.1536/ihj.17-604. Epub 2018 Dec 5.
828 Growth hormone attenuates skeletal muscle changes in experimental chronic heart failure.Growth Horm IGF Res. 2010 Apr;20(2):149-55. doi: 10.1016/j.ghir.2009.11.007. Epub 2010 Jan 8.
829 Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure.Physiol Genomics. 2012 Feb 1;44(2):162-72. doi: 10.1152/physiolgenomics.00016.2011. Epub 2011 Nov 29.
830 Depressed responsiveness of phospholipase C isoenzymes to phosphatidic acid in congestive heart failure.J Mol Cell Cardiol. 2001 Mar;33(3):431-40. doi: 10.1006/jmcc.2000.1315.
831 Ventricular adrenomedullin system in the transition from LVH to heart failure in rats.Hypertension. 2003 Mar;41(3):512-8. doi: 10.1161/01.HYP.0000053447.64213.C4. Epub 2003 Feb 3.
832 Renalase deficiency in heart failure model of rats--a potential mechanism underlying circulating norepinephrine accumulation.PLoS One. 2011 Jan 31;6(1):e14633. doi: 10.1371/journal.pone.0014633.
833 Phosphoproteome mapping of cardiomyocyte mitochondria in a rat model of heart failure.Mol Cell Biochem. 2014 Apr;389(1-2):159-67. doi: 10.1007/s11010-013-1937-7. Epub 2014 Jan 7.
834 Stretching single titin molecules from failing human hearts reveals titin's role in blunting cardiac kinetic reserve.Cardiovasc Res. 2020 Jan 1;116(1):127-137. doi: 10.1093/cvr/cvz043.