General Information of Drug Combination (ID: DCGYBN7)

Drug Combination Name
Decitabine Tetrahydrouridine
Indication
Disease Entry Status REF
Metastatic Pancreatic Adenocarcinoma Phase 1 [1]
Component Drugs Decitabine   DMQL8XJ Tetrahydrouridine   DMR5GSB
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Decitabine
Disease Entry ICD 11 Status REF
Acute myelogenous leukaemia 2A41 Approved [2]
Adult acute monocytic leukemia N.A. Approved [2]
Myelodysplastic syndrome 2A37 Approved [3]
Refractory chronic myeloid leukaemia 2A20 Approved [2]
Decitabine Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Human Deoxyribonucleic acid (hDNA) TTUTN1I NOUNIPROTAC Modulator [26]
------------------------------------------------------------------------------------
Decitabine Interacts with 2 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytidine aminohydrolase (CDA) DEKEDRC CDD_HUMAN Metabolism [27]
Cytidine deaminase (cdd) DEYILK4 E0TLJ6_MYCHH Metabolism [28]
------------------------------------------------------------------------------------
Decitabine Interacts with 1481 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Cytidine deaminase (CDA) OT3HXP6N CDD_HUMAN Increases Degradation [29]
Collagenase 3 (MMP13) OTY8BZIE MMP13_HUMAN Increases Expression [30]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Affects Expression [31]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Increases Expression [32]
Multidrug resistance-associated protein 1 (ABCC1) OTGUN89S MRP1_HUMAN Increases Expression [32]
Reduced folate transporter (SLC19A1) OTWB0BTO S19A1_HUMAN Increases Expression [32]
Folylpolyglutamate synthase, mitochondrial (FPGS) OTW3F1ZE FOLC_HUMAN Increases Expression [32]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Increases Expression [32]
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Increases Expression [33]
T-box transcription factor TBX3 (TBX3) OTM64N7K TBX3_HUMAN Increases Expression [5]
Claudin-3 (CLDN3) OT71MN9S CLD3_HUMAN Increases Expression [5]
Protein MTSS 1 (MTSS1) OT5DTDO2 MTSS1_HUMAN Increases Expression [5]
Acyl-CoA (FADS1) OTUYOYHX FADS1_HUMAN Increases Expression [5]
Gremlin-1 (GREM1) OTCK4IGV GREM1_HUMAN Increases Expression [5]
Cystatin-F (CST7) OTQWZUVQ CYTF_HUMAN Increases Expression [5]
Zinc finger protein SNAI1 (SNAI1) OTDPYAMC SNAI1_HUMAN Increases Expression [5]
Urokinase-type plasminogen activator (PLAU) OTX0QGKK UROK_HUMAN Increases Expression [5]
Retinol-binding protein 4 (RBP4) OTL9RBH5 RET4_HUMAN Increases Expression [5]
Plasminogen activator inhibitor 2 (SERPINB2) OT72QLZB PAI2_HUMAN Increases Expression [5]
Plasminogen activator inhibitor 1 (SERPINE1) OTT0MPQ3 PAI1_HUMAN Increases Expression [5]
Tyrosine-protein kinase Fyn (FYN) OTLSLVZS FYN_HUMAN Increases Expression [5]
Thrombomodulin (THBD) OT8VHLKY TRBM_HUMAN Increases Expression [5]
Procathepsin L (CTSL) OTYTUW29 CATL1_HUMAN Increases Expression [5]
Annexin A5 (ANXA5) OTZS877V ANXA5_HUMAN Increases Expression [5]
Interleukin-6 receptor subunit alpha (IL6R) OTCQL07Z IL6RA_HUMAN Increases Expression [5]
Intercellular adhesion molecule 2 (ICAM2) OT3E070F ICAM2_HUMAN Increases Expression [5]
Amphiregulin (AREG) OTJFOR67 AREG_HUMAN Increases Expression [5]
Insulin-like growth factor-binding protein 3 (IGFBP3) OTIX63TX IBP3_HUMAN Increases Expression [5]
Bone morphogenetic protein 7 (BMP7) OTYATP2K BMP7_HUMAN Increases Expression [5]
Follistatin (FST) OTRIVK9Y FST_HUMAN Increases Expression [5]
Interferon-induced GTP-binding protein Mx1 (MX1) OT6X8G5T MX1_HUMAN Increases Expression [5]
5'-nucleotidase (NT5E) OT7J5LT6 5NTD_HUMAN Increases Expression [5]
Brain-derived neurotrophic factor (BDNF) OTLGH7EW BDNF_HUMAN Increases Expression [5]
Proteinase-activated receptor 1 (F2R) OT4WVWBO PAR1_HUMAN Increases Expression [5]
Paired box protein Pax-6 (PAX6) OTOC9876 PAX6_HUMAN Increases Expression [5]
Homeobox protein MSX-1 (MSX1) OT5U41ZP MSX1_HUMAN Increases Expression [5]
Nitric oxide synthase 3 (NOS3) OTLDT7NR NOS3_HUMAN Increases Expression [5]
Small proline-rich protein 2A (SPRR2A) OT62ZU6B SPR2A_HUMAN Increases Expression [5]
Nuclear receptor ROR-alpha (RORA) OTGQT12P RORA_HUMAN Increases Expression [5]
Metalloproteinase inhibitor 3 (TIMP3) OTDGQAD1 TIMP3_HUMAN Increases Expression [5]
Regulator of G-protein signaling 2 (RGS2) OT0FSRW7 RGS2_HUMAN Increases Expression [5]
Tumor necrosis factor ligand superfamily member 9 (TNFSF9) OTV9L89D TNFL9_HUMAN Increases Expression [5]
Peptidyl-prolyl cis-trans isomerase C (PPIC) OTY5Q42N PPIC_HUMAN Increases Expression [5]
Retinaldehyde dehydrogenase 3 (ALDH1A3) OT1C9NKQ AL1A3_HUMAN Increases Expression [5]
DNA-binding protein inhibitor ID-4 (ID4) OTPMJ39I ID4_HUMAN Increases Expression [5]
Cyclin-dependent kinase 4 inhibitor D (CDKN2D) OT2TTZPZ CDN2D_HUMAN Increases Expression [5]
Myeloid leukemia factor 1 (MLF1) OTC5BKHU MLF1_HUMAN Increases Expression [5]
Caveolin-1 (CAV1) OTEZUR1L CAV1_HUMAN Increases Expression [5]
Elongation factor 1-alpha 2 (EEF1A2) OT9Z23K5 EF1A2_HUMAN Increases Expression [5]
Secernin-1 (SCRN1) OTELM5C2 SCRN1_HUMAN Increases Expression [5]
Runt-related transcription factor 3 (RUNX3) OTITK1XD RUNX3_HUMAN Increases Expression [5]
Interleukin-27 subunit beta (EBI3) OT0LF3D7 IL27B_HUMAN Increases Expression [5]
Metastasis-suppressor KiSS-1 (KISS1) OT6IE3K2 KISS1_HUMAN Increases Expression [5]
Insulin-like growth factor-binding protein 7 (IGFBP7) OT1D416P IBP7_HUMAN Increases Expression [5]
Melanoma-derived growth regulatory protein (MIA) OTG5FN5S MIA_HUMAN Increases Expression [5]
Filamin-A-interacting protein 1 (FILIP1) OTMZD6D4 FLIP1_HUMAN Increases Expression [5]
Methyl-CpG-binding domain protein 3-like 2 (MBD3L2) OTTG4S9O MB3L2_HUMAN Increases Expression [5]
Transcription factor AP-2 gamma (TFAP2C) OTUDIW05 AP2C_HUMAN Increases Expression [5]
KiSS-1 receptor (KISS1R) OTQA3J6G KISSR_HUMAN Increases Expression [5]
E3 ubiquitin-protein ligase CHFR (CHFR) OTRAD2TT CHFR_HUMAN Increases Expression [5]
Perilipin-2 (PLIN2) OTRXJ9UN PLIN2_HUMAN Increases Expression [5]
Fibronectin type III and SPRY domain-containing protein 1 (FSD1) OT8P6PT3 FSD1_HUMAN Increases Expression [5]
Spermatogenic leucine zipper protein 1 (SPZ1) OTQH8HJ5 SPZ1_HUMAN Increases Expression [5]
Epoxide hydrolase 3 (EPHX3) OTU7LW2F EPHX3_HUMAN Increases Expression [5]
Serine/threonine-protein kinase MARK1 (MARK1) OTP7KL47 MARK1_HUMAN Increases Expression [5]
Apoptosis-associated speck-like protein containing a CARD (PYCARD) OT67RON3 ASC_HUMAN Increases Expression [5]
Zinc finger protein PLAGL1 (PLAGL1) OTZAO900 PLAL1_HUMAN Increases Expression [5]
Insulin receptor substrate 2 (IRS2) OT46MJBE IRS2_HUMAN Increases Expression [5]
IgGFc-binding protein (FCGBP) OT63T6XQ FCGBP_HUMAN Increases Expression [5]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Increases Expression [34]
DNA cytosine-5)-methyltransferase 1 (DNMT1) OTM2DGTK DNMT1_HUMAN Decreases Expression [34]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Affects Expression [6]
Dihydropyrimidine dehydrogenase (DPYD) OTWRF2NR DPYD_HUMAN Increases Expression [35]
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) OT5I4Y9K PLCB_HUMAN Increases Expression [7]
Homeobox protein Nkx-2.8 (NKX2-8) OT6Q3DJ0 NKX28_HUMAN Increases Expression [7]
Phospholipid phosphatase 2 (PLPP2) OT0BQAXX PLPP2_HUMAN Increases Expression [7]
Methyl-CpG-binding domain protein 3 (MBD3) OTRL76H5 MBD3_HUMAN Increases Expression [7]
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) OTBPMIMW G3P_HUMAN Increases Expression [7]
Alpha-enolase (ENO1) OTB1KWJS ENOA_HUMAN Increases Expression [7]
U1 small nuclear ribonucleoprotein 70 kDa (SNRNP70) OTP52YZ3 RU17_HUMAN Increases Expression [7]
Fructose-bisphosphate aldolase C (ALDOC) OTEC13I5 ALDOC_HUMAN Increases Expression [7]
Retinoic acid receptor gamma (RARG) OT8LHMDH RARG_HUMAN Increases Expression [7]
Keratin, type II cytoskeletal 5 (KRT5) OTVGI9HT K2C5_HUMAN Increases Expression [7]
Fos-related antigen 2 (FOSL2) OT3MT9HJ FOSL2_HUMAN Increases Expression [7]
Insulin-like growth factor-binding protein 6 (IGFBP6) OTW878VI IBP6_HUMAN Increases Expression [7]
Protein-lysine 6-oxidase (LOX) OT1C2HIU LYOX_HUMAN Increases Expression [7]
Retinoic acid receptor RXR-beta (RXRB) OTNPDXG2 RXRB_HUMAN Increases Expression [7]
E3 ubiquitin-protein ligase TRIM23 (TRIM23) OTVIGJ4T TRI23_HUMAN Increases Expression [7]
Lysine-specific demethylase 5C (KDM5C) OTZ6E0HY KDM5C_HUMAN Increases Expression [7]
Ran GTPase-activating protein 1 (RANGAP1) OTZGD3LJ RAGP1_HUMAN Increases Expression [7]
Sodium- and chloride-dependent creatine transporter 1 (SLC6A8) OT88C8JA SC6A8_HUMAN Increases Expression [7]
ADP-ribosylation factor-like protein 4D (ARL4D) OTG5I3KU ARL4D_HUMAN Increases Expression [7]
Ras-related protein Rab-5C (RAB5C) OTQE5QQ2 RAB5C_HUMAN Increases Expression [7]
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) OTSMBXMF HNRPF_HUMAN Increases Expression [7]
5'-AMP-activated protein kinase subunit gamma-1 (PRKAG1) OTW00PRY AAKG1_HUMAN Increases Expression [7]
SCAN domain-containing protein 1 (SCAND1) OTRG0AGH SCND1_HUMAN Increases Expression [7]
AP-1 complex subunit sigma-1A (AP1S1) OTQ2H8DN AP1S1_HUMAN Increases Expression [7]
Neuronal calcium sensor 1 (NCS1) OT6JHAWM NCS1_HUMAN Increases Expression [7]
Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) OT2CF1E6 IF4G1_HUMAN Increases Expression [7]
Amyloid beta precursor like protein 2 (APLP2) OTTFE53M APLP2_HUMAN Increases Expression [7]
kinase isozyme 2, mitochondrial (PDK2) OTM436F9 PDK2_HUMAN Increases Expression [7]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Increases Expression [7]
Leucine-rich repeat-containing protein 23 (LRRC23) OTVK31UE LRC23_HUMAN Increases Expression [7]
Docking protein 4 (DOK4) OTUEWLG8 DOK4_HUMAN Increases Expression [7]
Protein NDRG1 (NDRG1) OTVO66BO NDRG1_HUMAN Increases Expression [7]
Histone deacetylase 2 (HDAC2) OTUYVFKN HDAC2_HUMAN Decreases Expression [7]
Histone acetyltransferase KAT5 (KAT5) OTL7257A KAT5_HUMAN Increases Expression [7]
Ethanolamine-phosphate cytidylyltransferase (PCYT2) OTT8TAEA PCY2_HUMAN Increases Expression [7]
Protein NipSnap homolog 1 (NIPSNAP1) OTKXKUT8 NIPS1_HUMAN Increases Expression [7]
Enoyl- reductase, mitochondrial (MECR) OTJQ5XKQ MECR_HUMAN Increases Expression [7]
Angiopoietin-related protein 4 (ANGPTL4) OTQL5SPX ANGL4_HUMAN Increases Expression [7]
Large ribosomal subunit protein mL66 (MRPS18A) OTFCBPX2 RT18A_HUMAN Increases Expression [7]
Nuclear receptor-binding protein (NRBP1) OTRWEJ65 NRBP_HUMAN Increases Expression [7]
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (MAN1B1) OTI780UB MA1B1_HUMAN Increases Expression [7]
Solute carrier family 12 member 4 (SLC12A4) OT21JMDH S12A4_HUMAN Increases Expression [7]
Calcium-regulated heat-stable protein 1 (CARHSP1) OTAUG6Y9 CHSP1_HUMAN Increases Expression [7]
Ribosomal RNA-processing protein 7 homolog A (RRP7A) OTYFNQUC RRP7A_HUMAN Increases Expression [7]
Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2) OTYOTM2B NUBP2_HUMAN Increases Expression [7]
Prostate-specific antigen (KLK3) OTFGSBFJ KLK3_HUMAN Increases Expression [36]
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Increases Expression [36]
Protein TMEPAI (PMEPA1) OTY8Z9UF PMEPA_HUMAN Increases Expression [36]
Homeobox protein Nkx-3.1 (NKX3-1) OT0DO6ZU NKX31_HUMAN Increases Expression [36]
tRNA (TRDMT1) OTAYQ8ZF TRDMT_HUMAN Decreases Expression [37]
Adenomatous polyposis coli protein (APC) OTKV0TIK APC_HUMAN Decreases Methylation [37]
Scavenger receptor class A member 3 (SCARA3) OT46I38Y SCAR3_HUMAN Decreases Methylation [37]
DNA (DNMT3A) OTEJP0GH DNM3A_HUMAN Decreases Expression [37]
Guided entry of tail-anchored proteins factor 1 (GET1) OTQJU3OJ GET1_HUMAN Increases Expression [38]
ATP-binding cassette sub-family C member 5 (ABCC5) OT34G4US MRP5_HUMAN Increases Expression [38]
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Increases Expression [38]
Metallothionein-2 (MT2A) OTHOACHD MT2_HUMAN Increases Expression [38]
Cholecystokinin (CCK) OT1GCG0L CCKN_HUMAN Increases Expression [38]
Monocyte differentiation antigen CD14 (CD14) OT83GJ47 CD14_HUMAN Increases Expression [38]
Heat shock cognate 71 kDa protein (HSPA8) OTJI2RCI HSP7C_HUMAN Increases Expression [38]
Anosmin-1 (ANOS1) OTZJT4KN KALM_HUMAN Increases Expression [38]
Glycine dehydrogenase (GLDC) OTVVDNW0 GCSP_HUMAN Increases Expression [38]
SHC-transforming protein 1 (SHC1) OT1J5IRN SHC1_HUMAN Increases Expression [38]
GTP cyclohydrolase 1 (GCH1) OTOZ6NSL GCH1_HUMAN Increases Expression [38]
Syndecan-4 (SDC4) OTKUVUGZ SDC4_HUMAN Increases Expression [38]
Alpha-synuclein (SNCA) OTPWC1MR SYUA_HUMAN Increases Expression [38]
Transcription factor SOX-9 (SOX9) OTVDJFGN SOX9_HUMAN Increases Expression [38]
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) OT50L4XB ACADV_HUMAN Increases Expression [38]
Protein S100-A10 (S100A10) OTI71243 S10AA_HUMAN Increases Expression [38]
Dynein light chain 1, cytoplasmic (DYNLL1) OTR69LHT DYL1_HUMAN Increases Expression [38]
Metallothionein-1X (MT1X) OT9AKFVS MT1X_HUMAN Increases Expression [38]
Interferon-induced transmembrane protein 3 (IFITM3) OT2QP8D3 IFM3_HUMAN Increases Expression [38]
Myocyte-specific enhancer factor 2C (MEF2C) OTZGF1Y5 MEF2C_HUMAN Increases Expression [38]
ATP-sensitive inward rectifier potassium channel 8 (KCNJ8) OTZ8G8FE KCNJ8_HUMAN Increases Expression [38]
BDNF/NT-3 growth factors receptor (NTRK2) OTD557PU NTRK2_HUMAN Increases Expression [38]
Dual specificity protein phosphatase 6 (DUSP6) OT4H6RKW DUS6_HUMAN Increases Expression [38]
Myotubularin-related protein 6 (MTMR6) OTQPAWI3 MTMR6_HUMAN Increases Expression [38]
Transmembrane protein 212 (TMEM212) OTTWVUDE TM212_HUMAN Increases Expression [8]
Unconventional myosin-If (MYO1F) OTOAV4AR MYO1F_HUMAN Increases Expression [8]
GTP-binding protein 1 (GTPBP1) OTA9KV6C GTPB1_HUMAN Increases Expression [8]
Leukocyte-specific transcript 1 protein (LST1) OTUVG424 LST1_HUMAN Increases Expression [8]
Regulator of G-protein signaling 12 (RGS12) OTNCIQTH RGS12_HUMAN Increases Expression [8]
Rho guanine nucleotide exchange factor 10 (ARHGEF10) OTHJ1Y4I ARHGA_HUMAN Increases Expression [8]
Mothers against decapentaplegic homolog 7 (SMAD7) OTSLHWF4 SMAD7_HUMAN Increases Expression [8]
Tumor protein p73 (TP73) OT0LUO47 P73_HUMAN Decreases Methylation [8]
Monocarboxylate transporter 4 (SLC16A3) OTDIXEXY MOT4_HUMAN Increases Expression [8]
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) OTP45YKX P4HA2_HUMAN Increases Expression [8]
Insulin-induced gene 1 protein (INSIG1) OTZF5X1D INSI1_HUMAN Decreases Expression [8]
Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1) OTIK337D TGFI1_HUMAN Increases Expression [8]
Proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1) OT4PGEAB PPIP1_HUMAN Increases Expression [8]
GDP-mannose 4,6 dehydratase (GMDS) OTWV79YD GMDS_HUMAN Decreases Expression [8]
Leupaxin (LPXN) OTUNV3CK LPXN_HUMAN Increases Expression [8]
Leucine-rich repeat and calponin homology domain-containing protein 4 (LRCH4) OTJFA4AV LRCH4_HUMAN Increases Expression [8]
Transcription factor E2F6 (E2F6) OT2PN28R E2F6_HUMAN Decreases Expression [8]
Cell cycle checkpoint protein RAD17 (RAD17) OT1I93DT RAD17_HUMAN Decreases Expression [8]
SAM and SH3 domain-containing protein 3 (SASH3) OT0XGQ93 SASH3_HUMAN Increases Expression [8]
Transient receptor potential cation channel subfamily M member 2 (TRPM2) OTBMHWYV TRPM2_HUMAN Decreases Expression [8]
ATP-dependent DNA helicase Q5 (RECQL5) OTVZMP1Q RECQ5_HUMAN Decreases Expression [8]
Calmodulin-binding transcription activator 2 (CAMTA2) OT6PIWF4 CMTA2_HUMAN Increases Expression [8]
NADH dehydrogenase 1 alpha subcomplex subunit 7 (NDUFA7) OT8CV3H5 NDUA7_HUMAN Decreases Expression [8]
Alpha-1-antitrypsin (SERPINA1) OTACYW9J A1AT_HUMAN Increases Expression [8]
Erythropoietin (EPO) OTZ90CN4 EPO_HUMAN Increases Expression [8]
T-cell surface glycoprotein CD4 (CD4) OT7Z5LNF CD4_HUMAN Increases Expression [8]
Ferritin heavy chain (FTH1) OT6IFS0O FRIH_HUMAN Increases Expression [8]
Glycophorin-C (GYPC) OTOEDR7O GLPC_HUMAN Decreases Expression [8]
Aldehyde dehydrogenase, mitochondrial (ALDH2) OTKJ9I3N ALDH2_HUMAN Increases Expression [8]
Protein S100-A9 (S100A9) OTOARHCS S10A9_HUMAN Increases Expression [8]
Protein S100-A6 (S100A6) OTHHPZQ8 S10A6_HUMAN Increases Expression [8]
Epoxide hydrolase 1 (EPHX1) OTBKWQER HYEP_HUMAN Increases Expression [8]
Alpha-2A adrenergic receptor (ADRA2A) OTZFGOTP ADA2A_HUMAN Increases Expression [8]
Pro-cathepsin H (CTSH) OTLFL0DG CATH_HUMAN Increases Expression [8]
Serglycin (SRGN) OTFAVSX0 SRGN_HUMAN Increases Expression [8]
Transcriptional regulator ERG (ERG) OTOTX9VU ERG_HUMAN Increases Expression [8]
Bone marrow proteoglycan (PRG2) OT0BCPQG PRG2_HUMAN Increases Expression [8]
L-selectin (SELL) OT6RAJZR LYAM1_HUMAN Increases Expression [8]
Mast cell carboxypeptidase A (CPA3) OTOK8M0V CBPA3_HUMAN Increases Expression [8]
Aminopeptidase N (ANPEP) OTP3WYFD AMPN_HUMAN Increases Expression [8]
NAD(P)H dehydrogenase 1 (NQO1) OTZGGIVK NQO1_HUMAN Increases Expression [8]
Heat shock 70 kDa protein 6 (HSPA6) OTH4S7WB HSP76_HUMAN Increases Expression [8]
Galectin-3 (LGALS3) OTYQT0ZI LEG3_HUMAN Increases Expression [8]
Glutathione hydrolase 1 proenzyme (GGT1) OTYDA1Z7 GGT1_HUMAN Increases Expression [8]
Glutathione peroxidase 3 (GPX3) OT6PK94R GPX3_HUMAN Increases Expression [8]
Signal transducer CD24 (CD24) OT7CODJ4 CD24_HUMAN Increases Expression [8]
Protein S100-P (S100P) OTJCXNJG S100P_HUMAN Increases Expression [8]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Increases Expression [8]
High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) OTBZBL9Y FCERG_HUMAN Increases Expression [8]
Homeobox protein Hox-A9 (HOXA9) OTKNK5H0 HXA9_HUMAN Increases Expression [8]
Peroxiredoxin-2 (PRDX2) OTLWCY9T PRDX2_HUMAN Increases Expression [8]
Glycerol kinase (GK) OTK2YRA0 GLPK_HUMAN Decreases Expression [8]
Radixin (RDX) OTNSYUN6 RADI_HUMAN Increases Expression [8]
Peroxisomal biogenesis factor 19 (PEX19) OTQIDE9Z PEX19_HUMAN Decreases Expression [8]
DNA-binding protein inhibitor ID-1 (ID1) OTKGNZN5 ID1_HUMAN Increases Expression [8]
RNA-binding protein 34 (RBM34) OTX3LUGI RBM34_HUMAN Decreases Expression [8]
LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1) OT729S0T LIMS1_HUMAN Increases Expression [8]
Mannan-binding lectin serine protease 1 (MASP1) OTWWCNZP MASP1_HUMAN Decreases Expression [8]
CCAAT/enhancer-binding protein alpha (CEBPA) OTOM9OE4 CEBPA_HUMAN Decreases Methylation [8]
Cyclin-dependent kinase inhibitor 1C (CDKN1C) OTASTJ3Q CDN1C_HUMAN Increases Expression [8]
Ras-related protein Rab-13 (RAB13) OTIQ484I RAB13_HUMAN Increases Expression [8]
AP-1 complex subunit sigma-2 (AP1S2) OTZHJFYI AP1S2_HUMAN Increases Expression [8]
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (PIP4K2B) OTF1VGJ9 PI42B_HUMAN Decreases Expression [8]
Protein delta homolog 1 (DLK1) OTE1VLNB DLK1_HUMAN Increases Expression [8]
Single-stranded DNA-binding protein 2 (SSBP2) OTYG1G80 SSBP2_HUMAN Increases Expression [8]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) OTCO26FV HMCS1_HUMAN Decreases Expression [8]
DNA-binding protein inhibitor ID-2 (ID2) OT0U1D53 ID2_HUMAN Increases Expression [8]
DNA-binding protein inhibitor ID-3 (ID3) OTUULW5Z ID3_HUMAN Increases Expression [8]
Proteolipid protein 2 (PLP2) OTEZ4LOV PLP2_HUMAN Increases Expression [8]
Collagen alpha-1(XIV) chain (COL14A1) OTLNJ13O COEA1_HUMAN Increases Expression [8]
Follistatin-related protein 1 (FSTL1) OT6KEZUD FSTL1_HUMAN Increases Expression [8]
Src-like-adapter (SLA) OTV17DY2 SLAP1_HUMAN Increases Expression [8]
Polycystin-2 (PKD2) OTIXBU8H PKD2_HUMAN Increases Expression [8]
MORC family CW-type zinc finger protein 3 (MORC3) OT81NKVT MORC3_HUMAN Increases Expression [8]
Equilibrative nucleoside transporter 2 (SLC29A2) OTUAOB8T S29A2_HUMAN Decreases Expression [8]
Methylsterol monooxygenase 1 (MSMO1) OTKV62RZ MSMO1_HUMAN Decreases Expression [8]
Innate immunity activator protein (INAVA) OTGXNB86 INAVA_HUMAN Increases Expression [8]
La-related protein 7 (LARP7) OTLLOZTL LARP7_HUMAN Increases Expression [8]
PX domain-containing protein 1 (PXDC1) OTQUA3TG PXDC1_HUMAN Increases Expression [8]
Rootletin (CROCC) OTVNOZSM CROCC_HUMAN Increases Expression [8]
Histone H2A type 2-A (H2AC18) OTCE5JC7 H2A2A_HUMAN Increases Expression [8]
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) OT4IN0MV HSDL2_HUMAN Decreases Expression [8]
DNA dC->dU-editing enzyme APOBEC-3F (APOBEC3F) OT750IJM ABC3F_HUMAN Increases Expression [8]
Equilibrative nucleobase transporter 1 (SLC43A3) OTR60ZLA S43A3_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase Praja-1 (PJA1) OTFKTMEI PJA1_HUMAN Increases Expression [8]
F-box only protein 41 (FBXO41) OT5MC4TZ FBX41_HUMAN Decreases Expression [8]
C-type lectin domain family 2 member B (CLEC2B) OT0W0M0L CLC2B_HUMAN Decreases Expression [8]
Deleted in azoospermia-like (DAZL) OTZMTD4R DAZL_HUMAN Increases Expression [8]
Primary cilium assembly protein FAM149B1 (FAM149B1) OTUBPEJ6 F149B_HUMAN Increases Expression [8]
Membrane-spanning 4-domains subfamily A member 3 (MS4A3) OT0CEJOO MS4A3_HUMAN Increases Expression [8]
Small G protein signaling modulator 3 (SGSM3) OTIB1P8A SGSM3_HUMAN Decreases Expression [8]
Protocadherin-16 (DCHS1) OTW3GX62 PCD16_HUMAN Increases Expression [8]
Serine protease FAM111A (FAM111A) OTVLARLG F111A_HUMAN Increases Expression [8]
Dehydrogenase/reductase SDR family member 9 (DHRS9) OTB1WOZA DHRS9_HUMAN Increases Expression [8]
Ciliogenesis and planar polarity effector 2 (CPLANE2) OTUQO14U CPLN2_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase TRIM8 (TRIM8) OTS6JFR0 TRIM8_HUMAN Increases Expression [8]
Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1) OT4U7SBG GBRL1_HUMAN Increases Expression [8]
Thiol S-methyltransferase TMT1A (TMT1A) OT4IAAZP TMT1A_HUMAN Increases Expression [8]
Transcription factor IIIB 50 kDa subunit (BRF2) OT2C6TH2 BRF2_HUMAN Increases Expression [8]
Transcription initiation factor TFIID subunit 9B (TAF9B) OTORBI4I TAF9B_HUMAN Increases Expression [8]
Lysine-rich coiled-coil protein 1 (KRCC1) OTMMV6WZ KRCC1_HUMAN Increases Expression [8]
NTF2-related export protein 2 (NXT2) OTK82YVT NXT2_HUMAN Increases Expression [8]
DNA-directed RNA polymerase III subunit RPC5 (POLR3E) OT69PWBM RPC5_HUMAN Decreases Expression [8]
THUMP domain-containing protein 1 (THUMPD1) OTKU8KWH THUM1_HUMAN Increases Expression [8]
Sphingosine kinase 1 (SPHK1) OTWYPBVD SPHK1_HUMAN Increases Expression [8]
Regulator of telomere elongation helicase 1 (RTEL1) OTI3PJCT RTEL1_HUMAN Decreases Expression [8]
Complement C1r subcomponent-like protein (C1RL) OTRTQWRV C1RL_HUMAN Increases Expression [8]
Cardiotrophin-like cytokine factor 1 (CLCF1) OTHQUDDI CLCF1_HUMAN Increases Expression [8]
Protein FAM8A1 (FAM8A1) OT1QVTGS FA8A1_HUMAN Increases Expression [8]
Tripartite motif-containing protein 10 (TRIM10) OTEO4UCZ TRI10_HUMAN Decreases Expression [8]
Peptide chain release factor 1-like, mitochondrial (MTRF1L) OTVX5QEO RF1ML_HUMAN Increases Expression [8]
Switch-associated protein 70 (SWAP70) OTPHT2QD SWP70_HUMAN Increases Expression [8]
DnaJ homolog subfamily C member 12 (DNAJC12) OTNU59PT DJC12_HUMAN Decreases Expression [8]
Disco-interacting protein 2 homolog C (DIP2C) OTVNSS2T DIP2C_HUMAN Increases Expression [8]
Small ribosomal subunit protein bS1m (MRPS28) OT8CLJ6M RT28_HUMAN Decreases Expression [8]
Insulin-induced gene 2 protein (INSIG2) OTX4VY51 INSI2_HUMAN Increases Expression [8]
Sorting nexin-13 (SNX13) OTB7IB7X SNX13_HUMAN Decreases Expression [8]
Sorting nexin-10 (SNX10) OT05B7BT SNX10_HUMAN Increases Expression [8]
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) OTTLD0KB SQOR_HUMAN Increases Expression [8]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Increases Expression [39]
Glutathione S-transferase P (GSTP1) OTLP0A0Y GSTP1_HUMAN Decreases Methylation [40]
Ras association domain-containing protein 1 (RASSF1) OTEZIPB7 RASF1_HUMAN Decreases Methylation [40]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Decreases Methylation [41]
Serine/threonine-protein kinase pim-1 (PIM1) OTWEKXTU PIM1_HUMAN Increases Expression [42]
SH2/SH3 adapter protein NCK1 (NCK1) OTKYZ4OP NCK1_HUMAN Increases Expression [42]
Monocarboxylate transporter 1 (SLC16A1) OTW1UTZ7 MOT1_HUMAN Increases Expression [42]
E3 ubiquitin-protein ligase pellino homolog 1 (PELI1) OTMLBCLC PELI1_HUMAN Increases Expression [42]
GTP-binding protein 2 (GTPBP2) OTOJ1KUA GTPB2_HUMAN Increases Expression [42]
Lysosome-associated membrane glycoprotein 3 (LAMP3) OTN0XL3W LAMP3_HUMAN Increases Expression [42]
Aryl hydrocarbon receptor repressor (AHRR) OTSJ12W6 AHRR_HUMAN Increases Expression [43]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Increases Expression [43]
Progesterone receptor (PGR) OT0FZ3QE PRGR_HUMAN Increases Expression [43]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Decreases Expression [43]
Glutathione S-transferase omega-1 (GSTO1) OTUJ93MN GSTO1_HUMAN Increases Expression [44]
Cytoglobin (CYGB) OTX153DQ CYGB_HUMAN Increases Expression [45]
Aldehyde dehydrogenase 1A1 (ALDH1A1) OTCUWZKB AL1A1_HUMAN Affects Expression [46]
Nestin (NES) OTZ9PZ14 NEST_HUMAN Affects Expression [46]
Hyaluronidase-1 (HYAL1) OT2SJN0X HYAL1_HUMAN Affects Expression [46]
Protein shisa-3 homolog (SHISA3) OTE8TPCP SHSA3_HUMAN Affects Expression [10]
Protein tyrosine phosphatase domain-containing protein 1 (PTPDC1) OTTM4N1J PTPC1_HUMAN Affects Expression [10]
Myotubularin-related protein 11 (MTMR11) OTHL2O08 MTMRB_HUMAN Affects Expression [10]
Outer dynein arm-docking complex subunit 3 (ODAD3) OT30XE9U ODAD3_HUMAN Affects Expression [10]
RCC1 domain-containing protein 1 (RCCD1) OT60N06L RCCD1_HUMAN Affects Expression [10]
Protein FAM181B (FAM181B) OTGZHJ7K F181B_HUMAN Affects Expression [10]
MIF4G domain-containing protein (MIF4GD) OTEUG1GR MI4GD_HUMAN Affects Expression [10]
Deoxyribonuclease-2-alpha (DNASE2) OT6RC1BL DNS2A_HUMAN Affects Expression [10]
PDZ and LIM domain protein 1 (PDLIM1) OT4EGCPG PDLI1_HUMAN Affects Expression [10]
Activator of apoptosis harakiri (HRK) OTR4GWJ0 HRK_HUMAN Affects Expression [10]
Sulfotransferase 2B1 (SULT2B1) OT0QMKO3 ST2B1_HUMAN Affects Expression [10]
Toll-like receptor 4 (TLR4) OTP7ML3S TLR4_HUMAN Increases Expression [10]
NADH dehydrogenase iron-sulfur protein 8, mitochondrial (NDUFS8) OTMEAWKO NDUS8_HUMAN Increases Expression [47]
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) OTBPCU2O TR10A_HUMAN Affects Methylation [48]
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) OTWICA51 PSD12_HUMAN Affects Expression [10]
DNA fragmentation factor subunit alpha (DFFA) OTFPFMT8 DFFA_HUMAN Affects Expression [10]
Chloride intracellular channel protein 1 (CLIC1) OTYLFWNG CLIC1_HUMAN Decreases Expression [49]
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) OTOMP6TH PK3CD_HUMAN Increases Expression [50]
Beta-mannosidase (MANBA) OT5O61XL MANBA_HUMAN Affects Expression [10]
Ladinin-1 (LAD1) OT6YGTVX LAD1_HUMAN Affects Expression [10]
Delta-like protein 1 (DLL1) OTCKXBQR DLL1_HUMAN Affects Expression [10]
Beta-1,3-N-acetylglucosaminyltransferase manic fringe (MFNG) OTUX45ZF MFNG_HUMAN Affects Expression [10]
Class E basic helix-loop-helix protein 40 (BHLHE40) OTITX14U BHE40_HUMAN Affects Expression [10]
Suppressor of cytokine signaling 2 (SOCS2) OTBPNKJQ SOCS2_HUMAN Affects Expression [10]
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Increases Expression [51]
Telomerase reverse transcriptase (TERT) OT085VVA TERT_HUMAN Decreases Activity [52]
Serine/threonine-protein kinase Chk1 (CHEK1) OTTTI622 CHK1_HUMAN Affects Localization [53]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Affects Expression [10]
Tripeptidyl-peptidase 1 (TPP1) OT2LQ771 TPP1_HUMAN Affects Expression [10]
Phytanoyl-CoA dioxygenase, peroxisomal (PHYH) OTUG4BWA PAHX_HUMAN Affects Expression [10]
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) OTAAS85T TIM23_HUMAN Affects Expression [10]
Histone-lysine N-methyltransferase SETD1A (SETD1A) OTVVWRIC SET1A_HUMAN Affects Expression [10]
Phosphoribosylformylglycinamidine synthase (PFAS) OTCOBYYK PUR4_HUMAN Affects Expression [10]
Serine/threonine-protein kinase DCLK1 (DCLK1) OTVSPS98 DCLK1_HUMAN Affects Expression [23]
Angiopoietin-2 (ANGPT2) OTEQK65P ANGP2_HUMAN Increases Expression [16]
Centrin-3 (CETN3) OTG4PL7H CETN3_HUMAN Affects Expression [10]
ADAM DEC1 (ADAMDEC1) OTMT7ZMG ADEC1_HUMAN Increases Expression [16]
Glutathione S-transferase A4 (GSTA4) OTZ1USIA GSTA4_HUMAN Affects Expression [10]
Laminin subunit alpha-5 (LAMA5) OTIIXE4M LAMA5_HUMAN Affects Expression [10]
Protein phosphatase 1D (PPM1D) OT8NLZ9D PPM1D_HUMAN Increases Expression [10]
Monocarboxylate transporter 5 (SLC16A4) OT1YXBKC MOT5_HUMAN Affects Expression [23]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [21]
TOX high mobility group box family member 3 (TOX3) OTC9NR4W TOX3_HUMAN Affects Expression [10]
High affinity copper uptake protein 1 (SLC31A1) OTXLRTUB COPT1_HUMAN Increases Expression [54]
MutS protein homolog 4 (MSH4) OTJZMG1Z MSH4_HUMAN Increases Expression [18]
Melanoma-associated antigen B2 (MAGEB2) OTAGUVU5 MAGB2_HUMAN Increases Expression [55]
Calpain-5 (CAPN5) OTQ8QM7K CAN5_HUMAN Decreases Expression [21]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Affects Expression [56]
Suppressor of cytokine signaling 1 (SOCS1) OTWA9KFU SOCS1_HUMAN Increases Expression [57]
N-glycosylase/DNA lyase (OGG1) OTJ97TF3 OGG1_HUMAN Increases Expression [18]
Intermediate conductance calcium-activated potassium channel protein 4 (KCNN4) OTQKQ346 KCNN4_HUMAN Increases Expression [58]
Cytochrome P450 26A1 (CYP26A1) OTL1DFWV CP26A_HUMAN Affects Expression [10]
Septin-4 (SEPTIN4) OTD16B30 SEPT4_HUMAN Affects Expression [10]
Kunitz-type protease inhibitor 2 (SPINT2) OTQV7BKQ SPIT2_HUMAN Affects Expression [10]
Death-associated protein kinase 3 (DAPK3) OTLV7EKW DAPK3_HUMAN Increases Expression [59]
Heat shock 70 kDa protein 12A (HSPA12A) OTFOCDD6 HS12A_HUMAN Affects Expression [10]
RNA-binding protein Musashi homolog 1 (MSI1) OTAN4FSC MSI1H_HUMAN Decreases Expression [21]
ER membrane protein complex subunit 8 (EMC8) OTIUTHS1 EMC8_HUMAN Affects Expression [10]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Increases Expression [60]
Carbonic anhydrase 12 (CA12) OT6WNFU8 CAH12_HUMAN Increases Expression [16]
Synaptotagmin-7 (SYT7) OTBWAOWY SYT7_HUMAN Affects Expression [10]
Zinc finger protein SNAI2 (SNAI2) OT7Y8EJ2 SNAI2_HUMAN Decreases Expression [12]
Regulator of G-protein signaling 10 (RGS10) OTQ8N1QH RGS10_HUMAN Affects Expression [10]
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) OT80DZMT BUB1_HUMAN Affects Expression [10]
A-kinase anchor protein 7 isoforms alpha and beta (AKAP7) OT0L3PZ6 AKA7A_HUMAN Affects Expression [10]
Probable 18S rRNA (BUD23) OTJS7VU3 BUD23_HUMAN Decreases Expression [61]
ER lumen protein-retaining receptor 3 (KDELR3) OTW8C1V0 ERD23_HUMAN Affects Expression [10]
E3 ubiquitin ligase TRAF3IP2 (TRAF3IP2) OTLLZERL CIKS_HUMAN Affects Expression [10]
Synaptogyrin-1 (SYNGR1) OT0MBUK5 SNG1_HUMAN Affects Expression [10]
Alpha-endosulfine (ENSA) OT6T26HV ENSA_HUMAN Affects Expression [10]
Protein SSX4 (SSX4) OT0E4H2D SSX4_HUMAN Increases Expression [55]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L) OTJKOMXE BNI3L_HUMAN Affects Methylation [62]
Protein SOX-15 (SOX15) OTTB37I1 SOX15_HUMAN Increases Expression [10]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (GNG7) OTHS1L0E GBG7_HUMAN Affects Expression [10]
tRNA wybutosine-synthesizing protein 4 (LCMT2) OT4RUVCM TYW4_HUMAN Affects Expression [10]
BMP/retinoic acid-inducible neural-specific protein 1 (BRINP1) OTEUVSCP BRNP1_HUMAN Affects Expression [10]
Myelin protein zero-like protein 2 (MPZL2) OTKFNDUI MPZL2_HUMAN Affects Expression [10]
Vinexin (SORBS3) OTVEUODC VINEX_HUMAN Affects Expression [10]
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) OTRNDZXB HNRPQ_HUMAN Affects Expression [10]
Lipid transferase CIDEA (CIDEA) OTDUTSOV CIDEA_HUMAN Increases Expression [63]
Forkhead box protein D2 (FOXD2) OTAF63YV FOXD2_HUMAN Affects Expression [10]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) OT8KME51 BUB1B_HUMAN Affects Expression [10]
Clathrin coat assembly protein AP180 (SNAP91) OTE3EXWZ AP180_HUMAN Affects Expression [10]
Perilipin-3 (PLIN3) OT9ZA7MR PLIN3_HUMAN Affects Expression [10]
Tyrosine-protein kinase JAK2 (JAK2) OTBIDOOR JAK2_HUMAN Decreases Methylation [64]
Protein diaphanous homolog 2 (DIAPH2) OTBEYFEZ DIAP2_HUMAN Affects Expression [10]
Receptor activity-modifying protein 2 (RAMP2) OTGQXLH5 RAMP2_HUMAN Affects Methylation [65]
E3 ubiquitin-protein ligase PPP1R11 (PPP1R11) OTSHYPPW PP1RB_HUMAN Affects Expression [10]
Inward rectifier potassium channel 13 (KCNJ13) OTG1CNND KCJ13_HUMAN Affects Expression [23]
Nibrin (NBN) OT73B5MD NBN_HUMAN Affects Localization [53]
Microphthalmia-associated transcription factor (MITF) OT6XJCZH MITF_HUMAN Decreases Expression [58]
Immunoglobulin superfamily member 3 (IGSF3) OT6GWBAF IGSF3_HUMAN Affects Expression [10]
Frizzled-7 (FZD7) OTTK3F6E FZD7_HUMAN Decreases Expression [21]
Astrotactin-2 (ASTN2) OTF0W2FJ ASTN2_HUMAN Affects Expression [10]
Cullin-associated NEDD8-dissociated protein 2 (CAND2) OTOMOG3R CAND2_HUMAN Affects Expression [10]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B) OTL9I7LO GA45B_HUMAN Affects Expression [10]
Transforming acidic coiled-coil-containing protein 1 (TACC1) OTGX20TE TACC1_HUMAN Affects Expression [10]
Transcription factor Maf (MAF) OT1GR3IZ MAF_HUMAN Affects Expression [66]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Increases Expression [67]
Glypican-4 (GPC4) OTUJ14DW GPC4_HUMAN Affects Expression [10]
Left-right determination factor 1 (LEFTY1) OT51HVC4 LFTY1_HUMAN Affects Expression [10]
PR domain zinc finger protein 1 (PRDM1) OTQLSVBS PRDM1_HUMAN Affects Expression [10]
Cancer/testis antigen 2 (CTAG2) OT8HISP4 CTAG2_HUMAN Increases Expression [55]
Solute carrier family 22 member 3 (SLC22A3) OTQYGVXX S22A3_HUMAN Affects Expression [10]
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (B3GALNT1) OT8GFSQL B3GL1_HUMAN Affects Expression [23]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) OTYG179K PR15A_HUMAN Affects Expression [10]
Tumor necrosis factor ligand superfamily member 13 (TNFSF13) OT90OWIO TNF13_HUMAN Affects Expression [23]
PRA1 family protein 3 (ARL6IP5) OTYZ6BEQ PRAF3_HUMAN Affects Expression [10]
Stanniocalcin-2 (STC2) OT86YP8G STC2_HUMAN Affects Expression [10]
DNA fragmentation factor subunit beta (DFFB) OTPBW5N5 DFFB_HUMAN Affects Methylation [13]
Regulator of G-protein signaling 20 (RGS20) OT6CGYHW RGS20_HUMAN Affects Expression [10]
Organic cation/carnitine transporter 2 (SLC22A5) OTC36TYB S22A5_HUMAN Increases Expression [68]
G antigen 7 (GAGE7) OTF8BTR9 GAGE7_HUMAN Increases Expression [55]
Bestrophin-1 (BEST1) OTWHE1ZC BEST1_HUMAN Affects Expression [10]
Slit homolog 2 protein (SLIT2) OTLS2RJ4 SLIT2_HUMAN Increases Expression [69]
Dickkopf-related protein 1 (DKK1) OTRDLUSP DKK1_HUMAN Increases Expression [58]
Transcription factor SOX-30 (SOX30) OTGT38E3 SOX30_HUMAN Increases Expression [70]
Tight junction protein ZO-3 (TJP3) OTC1K8HC ZO3_HUMAN Affects Expression [10]
Meiotic recombination protein REC8 homolog (REC8) OT6JAVXE REC8_HUMAN Increases Expression [16]
Neurexophilin-4 (NXPH4) OTV057AG NXPH4_HUMAN Decreases Expression [21]
Reticulon-3 (RTN3) OTGZ51QF RTN3_HUMAN Decreases Expression [21]
Cyclin-D1-binding protein 1 (CCNDBP1) OTBWG1M0 CCDB1_HUMAN Affects Expression [10]
Phenylalanine--tRNA ligase, mitochondrial (FARS2) OTXAK6F0 SYFM_HUMAN Affects Expression [10]
Mitogen-activated protein kinase kinase kinase 6 (MAP3K6) OTOE0Z1R M3K6_HUMAN Affects Expression [10]
Papilin (PAPLN) OTCJD85N PPN_HUMAN Affects Expression [10]
Fatty acid CoA ligase Acsl3 (ACSL3) OT3MWER1 ACSL3_HUMAN Increases Expression [71]
Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1) OT4TMERS NFAC1_HUMAN Decreases Expression [58]
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein (ASMTL) OTPUGCZO ASML_HUMAN Affects Expression [10]
C-X-C motif chemokine 14 (CXCL14) OTM189TA CXL14_HUMAN Increases Expression [72]
BAG family molecular chaperone regulator 2 (BAG2) OTI6LD27 BAG2_HUMAN Decreases Expression [21]
BAG family molecular chaperone regulator 3 (BAG3) OTVXYUDQ BAG3_HUMAN Affects Expression [10]
Serine/threonine-protein kinase LATS1 (LATS1) OTOOCG4R LATS1_HUMAN Affects Methylation [73]
Uridine diphosphate glucose pyrophosphatase NUDT14 (NUDT14) OTXX1OWL NUD14_HUMAN Affects Expression [10]
EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2) OT0I2B4J FBLN4_HUMAN Affects Expression [10]
Leucine-rich glioma-inactivated protein 1 (LGI1) OTPS77HO LGI1_HUMAN Affects Expression [10]
Reversion-inducing cysteine-rich protein with Kazal motifs (RECK) OT9QIHEQ RECK_HUMAN Affects Expression [74]
Actin-associated protein FAM107A (FAM107A) OTBG61YZ F107A_HUMAN Affects Expression [10]
Securin (PTTG1) OTIMYS4W PTTG1_HUMAN Affects Expression [10]
Amyloid-beta A4 precursor protein-binding family A member 3 (APBA3) OTAAATXF APBA3_HUMAN Affects Expression [10]
Complement factor D (CFD) OTLNRXB6 CFAD_HUMAN Affects Expression [10]
Coagulation factor XII (F12) OTBFD2FU FA12_HUMAN Affects Expression [10]
Adenosine deaminase (ADA) OTOX2872 ADA_HUMAN Affects Expression [10]
Argininosuccinate synthase (ASS1) OT4ZMG0Q ASSY_HUMAN Affects Expression [10]
Complement C5 (C5) OTSL3OIC CO5_HUMAN Affects Expression [10]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Affects Expression [23]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [10]
GTPase HRas (HRAS) OTWQN0DP RASH_HUMAN Decreases Expression [75]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Increases Expression [76]
Proenkephalin-B (PDYN) OTEJ6430 PDYN_HUMAN Affects Expression [10]
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Increases Secretion [77]
Collagen alpha-1(I) chain (COL1A1) OTI31178 CO1A1_HUMAN Increases Expression [78]
Apolipoprotein C-I (APOC1) OTA58CED APOC1_HUMAN Affects Expression [10]
C-X-C motif chemokine 10 (CXCL10) OTTLQ6S0 CXL10_HUMAN Affects Methylation [62]
Estrogen receptor (ESR1) OTKLU61J ESR1_HUMAN Decreases Expression [79]
Angiogenin (ANG) OT3ECS6P ANGI_HUMAN Affects Expression [10]
Interstitial collagenase (MMP1) OTI4I2V1 MMP1_HUMAN Affects Expression [23]
Muellerian-inhibiting factor (AMH) OT5FH4BD MIS_HUMAN Decreases Expression [21]
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) OTRT3F3U HMDH_HUMAN Affects Expression [10]
Tissue alpha-L-fucosidase (FUCA1) OTW71IK4 FUCO_HUMAN Affects Expression [10]
Annexin A1 (ANXA1) OT5OFDJC ANXA1_HUMAN Affects Expression [10]
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Decreases Expression [80]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Increases Expression [81]
Phosphatidylcholine-sterol acyltransferase (LCAT) OTRLMLK0 LCAT_HUMAN Affects Expression [10]
Semenogelin-1 (SEMG1) OT6Z4BPQ SEMG1_HUMAN Affects Expression [82]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Increases Expression [83]
Metallothionein-1A (MT1A) OTKBH52X MT1A_HUMAN Affects Expression [10]
Metallothionein-1F (MT1F) OTZVUYG1 MT1F_HUMAN Affects Expression [10]
Protein S100-A8 (S100A8) OTVMOB3F S10A8_HUMAN Affects Expression [84]
Ubiquitin-like protein ISG15 (ISG15) OT53QQ7N ISG15_HUMAN Affects Expression [10]
Alkaline phosphatase, placental type (ALPP) OTZU4G9W PPB1_HUMAN Affects Methylation [13]
Non-histone chromosomal protein HMG-17 (HMGN2) OTN20MEF HMGN2_HUMAN Affects Expression [10]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Increases Expression [85]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Increases Expression [77]
Large ribosomal subunit protein uL10 (RPLP0) OT3XKD6Y RLA0_HUMAN Decreases Expression [49]
Neuroendocrine protein 7B2 (SCG5) OTXSJMT1 7B2_HUMAN Increases Expression [86]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Affects Expression [10]
Fatty acid-binding protein, heart (FABP3) OT562DA1 FABPH_HUMAN Affects Expression [10]
Transcription factor AP-2-alpha (TFAP2A) OTMYT3NK AP2A_HUMAN Increases Expression [87]
Protein kinase C beta type (PRKCB) OTYQ0656 KPCB_HUMAN Affects Expression [10]
Keratin, type II cytoskeletal 8 (KRT8) OTTM4X11 K2C8_HUMAN Affects Expression [49]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Decreases Expression [75]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Increases Phosphorylation [88]
Low affinity immunoglobulin epsilon Fc receptor (FCER2) OTU40XWZ FCER2_HUMAN Affects Expression [10]
Nucleophosmin (NPM1) OTTBYYT0 NPM_HUMAN Decreases Methylation [64]
Tropomyosin alpha-3 chain (TPM3) OT5RU5G6 TPM3_HUMAN Decreases Expression [49]
Tyrosine 3-monooxygenase (TH) OT6ZORKP TY3H_HUMAN Increases Expression [89]
Glutathione peroxidase 1 (GPX1) OTE2O72Q GPX1_HUMAN Affects Expression [10]
Vitamin K-dependent protein S (PROS1) OTXQWNOI PROS_HUMAN Affects Expression [10]
Asialoglycoprotein receptor 1 (ASGR1) OTS99MJO ASGR1_HUMAN Affects Expression [10]
Beta-2 adrenergic receptor (ADRB2) OTSDOX4Q ADRB2_HUMAN Affects Expression [66]
Beta-hexosaminidase subunit beta (HEXB) OTROYLCR HEXB_HUMAN Affects Expression [10]
Heat shock protein HSP 90-alpha (HSP90AA1) OTLG1WPK HS90A_HUMAN Decreases Expression [49]
Galactose-1-phosphate uridylyltransferase (GALT) OTCATU66 GALT_HUMAN Affects Expression [10]
Tropomyosin beta chain (TPM2) OTA1L0P8 TPM2_HUMAN Affects Expression [23]
DNA excision repair protein ERCC-1 (ERCC1) OTNPYQHI ERCC1_HUMAN Decreases Expression [18]
Transcription factor Sp1 (SP1) OTISPT4X SP1_HUMAN Increases Expression [90]
Collagen alpha-2(I) chain (COL1A2) OTY7G382 CO1A2_HUMAN Increases Expression [78]
Rho-related GTP-binding protein RhoC (RHOC) OTOLE1FT RHOC_HUMAN Affects Expression [10]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Expression [91]
Amino acid transporter heavy chain SLC3A2 (SLC3A2) OTBR33M9 4F2_HUMAN Affects Expression [10]
Hepatocyte growth factor receptor (MET) OT7K55MU MET_HUMAN Decreases Expression [21]
Tyrosine-protein kinase HCK (HCK) OTRL6OSI HCK_HUMAN Increases Expression [92]
Integrin alpha-5 (ITGA5) OT3RCI67 ITA5_HUMAN Affects Expression [10]
Small ribosomal subunit protein uS2 (RPSA) OTJZHEGT RSSA_HUMAN Decreases Expression [21]
Proto-oncogene tyrosine-protein kinase ROS (ROS1) OTDSKUGE ROS1_HUMAN Increases Expression [93]
Neuromedin-B (NMB) OT4NLN6H NMB_HUMAN Increases Expression [16]
Gamma-enolase (ENO2) OTRODL0T ENOG_HUMAN Affects Expression [10]
Galectin-1 (LGALS1) OT8LDFWR LEG1_HUMAN Affects Expression [10]
High mobility group protein B1 (HMGB1) OT4B7CPF HMGB1_HUMAN Decreases Expression [21]
Retinol-binding protein 1 (RBP1) OTRP1MFC RET1_HUMAN Decreases Metabolism [94]
Fructose-1,6-bisphosphatase 1 (FBP1) OTQBANEP F16P1_HUMAN Decreases Methylation [95]
SPARC (SPARC) OTPN90H0 SPRC_HUMAN Increases Expression [96]
Platelet-derived growth factor receptor beta (PDGFRB) OTYSNK9Q PGFRB_HUMAN Increases Expression [16]
Lactase/phlorizin hydrolase (LCT) OT6GAZUG LPH_HUMAN Increases Expression [97]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Decreases Methylation [98]
DNA polymerase alpha catalytic subunit (POLA1) OT1WXFVY DPOLA_HUMAN Affects Methylation [13]
Interferon alpha-inducible protein 6 (IFI6) OTWOOAM4 IFI6_HUMAN Affects Expression [10]
Leukotriene A-4 hydrolase (LTA4H) OTWSZ0QT LKHA4_HUMAN Affects Expression [10]
Peroxisomal coenzyme A diphosphatase NUDT7 (NUDT7) OTCPOQ6W NUDT7_HUMAN Affects Expression [10]
Chimeric ERCC6-PGBD3 protein (ERCC6) OT2QZKSF ERPG3_HUMAN Increases Expression [18]
G antigen 4 (GAGE4) OTPB5C0O GAGE4_HUMAN Increases Expression [55]
Zinc finger protein GLI2 (GLI2) OTIRV97L GLI2_HUMAN Decreases Expression [21]
Peptide YY (PYY) OTXX6AF5 PYY_HUMAN Affects Expression [10]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Increases Expression [16]
Ras-related protein R-Ras (RRAS) OTBBF28C RRAS_HUMAN Affects Expression [10]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Expression [18]
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT) OT9LBJVN ODP2_HUMAN Affects Expression [10]
COUP transcription factor 1 (NR2F1) OTGWZWYL COT1_HUMAN Decreases Expression [21]
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) OTDP94F3 COX5B_HUMAN Increases Expression [49]
Retinoic acid receptor beta (RARB) OT367U3E RARB_HUMAN Decreases Metabolism [94]
Clusterin (CLU) OTQGG0JM CLUS_HUMAN Increases Expression [76]
Interferon regulatory factor 1 (IRF1) OT43DI6J IRF1_HUMAN Increases Expression [58]
Protein 4.1 (EPB41) OTGCFPV8 EPB41_HUMAN Affects Expression [23]
Integrin alpha-M (ITGAM) OTAG6HWU ITAM_HUMAN Affects Expression [84]
Ras-related protein Ral-B (RALB) OTFH203X RALB_HUMAN Affects Expression [10]
Fibroblast growth factor receptor 1 (FGFR1) OT4GLCXW FGFR1_HUMAN Decreases Expression [58]
DNA topoisomerase 2-alpha (TOP2A) OT6LPS08 TOP2A_HUMAN Affects Expression [10]
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Affects Methylation [99]
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) OTMKHVWC C1TC_HUMAN Affects Expression [10]
Proliferating cell nuclear antigen (PCNA) OTHZ1RIA PCNA_HUMAN Affects Methylation [13]
Neurofilament heavy polypeptide (NEFH) OTMSCW5I NFH_HUMAN Affects Expression [23]
Collagen alpha-1(XI) chain (COL11A1) OTB0DRMS COBA1_HUMAN Affects Expression [10]
Ski-like protein (SKIL) OTNBXH32 SKIL_HUMAN Affects Expression [10]
Alpha-actinin-1 (ACTN1) OTUCLNXH ACTN1_HUMAN Affects Methylation [13]
Interferon-induced transmembrane protein 1 (IFITM1) OTECO1G8 IFM1_HUMAN Affects Expression [10]
Secretogranin-2 (SCG2) OTUHXX8U SCG2_HUMAN Affects Expression [10]
Tartrate-resistant acid phosphatase type 5 (ACP5) OTBV4498 PPA5_HUMAN Affects Expression [23]
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) OTPWI88U CEAM1_HUMAN Affects Expression [10]
Translationally-controlled tumor protein (TPT1) OTHMTRJU TCTP_HUMAN Decreases Expression [49]
Delta-aminolevulinic acid dehydratase (ALAD) OTHM9GSH HEM2_HUMAN Affects Expression [10]
Troponin T, slow skeletal muscle (TNNT1) OT8PBOAR TNNT1_HUMAN Affects Expression [23]
Beta-enolase (ENO3) OT3HYKYI ENOB_HUMAN Affects Expression [10]
Phospholipase A2, membrane associated (PLA2G2A) OT1NY7BF PA2GA_HUMAN Increases Expression [100]
Pyruvate kinase PKM (PKM) OTLHHMC2 KPYM_HUMAN Affects Methylation [13]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Increases Expression [101]
Myosin light chain 6B (MYL6B) OTWTRGT7 MYL6B_HUMAN Affects Expression [10]
Insulin-degrading enzyme (IDE) OT5GQTJ5 IDE_HUMAN Affects Expression [10]
Matrix metalloproteinase-9 (MMP9) OTB2QDAV MMP9_HUMAN Decreases Expression [15]
Indoleamine 2,3-dioxygenase 1 (IDO1) OT91DBN7 I23O1_HUMAN Affects Expression [10]
Protein C-ets-1 (ETS1) OT4LVGDN ETS1_HUMAN Increases Expression [90]
Junction plakoglobin (JUP) OTUH7VMO PLAK_HUMAN Increases Expression [102]
Leukemia inhibitory factor (LIF) OTO46S5S LIF_HUMAN Increases Expression [58]
Ras-related C3 botulinum toxin substrate 2 (RAC2) OTAOHFNH RAC2_HUMAN Affects Expression [23]
Fos-related antigen 1 (FOSL1) OT9YTYMB FOSL1_HUMAN Increases Expression [16]
Transcription factor 4 (TCF4) OTB9ASTK ITF2_HUMAN Affects Expression [10]
V(D)J recombination-activating protein 1 (RAG1) OTV131E4 RAG1_HUMAN Increases Expression [16]
CD44 antigen (CD44) OT9TTJ41 CD44_HUMAN Affects Expression [10]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Expression [53]
Platelet-derived growth factor receptor alpha (PDGFRA) OTDJXUCN PGFRA_HUMAN Affects Expression [10]
Epithelial cell adhesion molecule (EPCAM) OTHBZK5X EPCAM_HUMAN Affects Expression [103]
Methylated-DNA--protein-cysteine methyltransferase (MGMT) OT40A9WH MGMT_HUMAN Increases Expression [104]
Cysteine-rich secretory protein 2 (CRISP2) OT8HLTV5 CRIS2_HUMAN Increases Expression [55]
Interleukin-7 receptor subunit alpha (IL7R) OTBMFLQQ IL7RA_HUMAN Affects Methylation [105]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) OTGVC9MY PLCG2_HUMAN Affects Expression [10]
Transmembrane protein 11, mitochondrial (TMEM11) OTL9HDEY TMM11_HUMAN Affects Methylation [13]
Transcription factor JunB (JUNB) OTG2JXV5 JUNB_HUMAN Affects Expression [106]
Gap junction alpha-1 protein (GJA1) OTT94MKL CXA1_HUMAN Affects Expression [107]
CCAAT/enhancer-binding protein beta (CEBPB) OTM9MQIA CEBPB_HUMAN Affects Expression [10]
HLA class I histocompatibility antigen, alpha chain G (HLA-G) OTMLK1KN HLAG_HUMAN Increases Expression [108]
Transcription factor PU.1 (SPI1) OTVCA1D0 SPI1_HUMAN Affects Methylation [109]
Integrin beta-5 (ITGB5) OT21MF51 ITB5_HUMAN Affects Expression [10]
Early growth response protein 1 (EGR1) OTCP6XGZ EGR1_HUMAN Increases Expression [16]
Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2) OTGNDWUO GBRG2_HUMAN Increases Expression [16]
Pituitary adenylate cyclase-activating polypeptide (ADCYAP1) OT0LQH93 PACA_HUMAN Increases Expression [110]
Lymphocyte activation gene 3 protein (LAG3) OTKGOFJW LAG3_HUMAN Affects Expression [10]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Increases Expression [16]
Cadherin-2 (CDH2) OTH0Y56P CADH2_HUMAN Decreases Expression [12]
Troponin I, cardiac muscle (TNNI3) OT65E12V TNNI3_HUMAN Affects Expression [10]
Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2) OT8DXMS3 E2AK2_HUMAN Affects Methylation [13]
Casein kinase II subunit alpha' (CSNK2A2) OT7MA2LV CSK22_HUMAN Increases Expression [90]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Increases Expression [90]
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) OTDS2EAR TNR1B_HUMAN Increases Expression [111]
Lamin-B1 (LMNB1) OT100T3P LMNB1_HUMAN Decreases Expression [21]
Integrin alpha-X (ITGAX) OTOGIMHE ITAX_HUMAN Affects Expression [10]
Neurotrophin-3 (NTF3) OTK75XGA NTF3_HUMAN Affects Expression [10]
Calpain-3 (CAPN3) OTCHG3YK CAN3_HUMAN Decreases Expression [58]
Ephrin-A1 (EFNA1) OTU2NUA2 EFNA1_HUMAN Affects Expression [10]
Myelin and lymphocyte protein (MAL) OTBM30SW MAL_HUMAN Increases Expression [112]
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (FUT3) OTXQ6P8R FUT3_HUMAN Affects Expression [113]
Amine oxidase A (MAOA) OT8NIWMQ AOFA_HUMAN Affects Expression [10]
fMet-Leu-Phe receptor (FPR1) OTFF9I6W FPR1_HUMAN Decreases Expression [114]
Cannabinoid receptor 1 (CNR1) OTEALO6G CNR1_HUMAN Increases Expression [115]
Diamine acetyltransferase 1 (SAT1) OT52AU22 SAT1_HUMAN Affects Expression [23]
Ephrin type-A receptor 1 (EPHA1) OTGJMRZ0 EPHA1_HUMAN Increases Expression [116]
Biglycan (BGN) OT3AV6IF PGS1_HUMAN Affects Expression [10]
Nucleoside diphosphate kinase B (NME2) OTCYGLHV NDKB_HUMAN Affects Methylation [13]
Potassium voltage-gated channel subfamily A member 5 (KCNA5) OTHI2N71 KCNA5_HUMAN Affects Expression [10]
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) OTBZKX4P ROA2_HUMAN Decreases Expression [49]
Cyclin-O (CCNO) OT68CH0B CCNO_HUMAN Affects Expression [10]
Carbonic anhydrase 4 (CA4) OT3K93LZ CAH4_HUMAN Affects Expression [10]
Prostaglandin G/H synthase 1 (PTGS1) OTHCRLEC PGH1_HUMAN Affects Expression [10]
Sarcoplasmic reticulum histidine-rich calcium-binding protein (HRC) OTDLEJ4T SRCH_HUMAN Affects Expression [10]
Receptor-type tyrosine-protein phosphatase gamma (PTPRG) OT9N2WOF PTPRG_HUMAN Affects Methylation [117]
Plasma membrane calcium-transporting ATPase 4 (ATP2B4) OTMWFDAC AT2B4_HUMAN Affects Expression [10]
Endothelial transcription factor GATA-2 (GATA2) OTBP2QQ2 GATA2_HUMAN Increases Expression [110]
Interleukin-32 (IL32) OT3FHZ81 IL32_HUMAN Affects Expression [10]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Decreases Expression [118]
ER lumen protein-retaining receptor 1 (KDELR1) OT8YBS5G ERD21_HUMAN Affects Methylation [13]
Interleukin-4 receptor subunit alpha (IL4R) OTTXOTCW IL4RA_HUMAN Affects Expression [23]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Increases Expression [119]
Tenascin (TNC) OTK4FSHR TENA_HUMAN Affects Expression [10]
Collagen alpha-2(VIII) chain (COL8A2) OTASWJ69 CO8A2_HUMAN Increases Expression [16]
Alpha-1D adrenergic receptor (ADRA1D) OTW2CD1O ADA1D_HUMAN Increases Expression [120]
DnaJ homolog subfamily B member 2 (DNAJB2) OTZHPV5M DNJB2_HUMAN Affects Expression [10]
Metallothionein-3 (MT3) OTVCZ7HI MT3_HUMAN Increases Expression [121]
Rhombotin-2 (LMO2) OTCC370G RBTN2_HUMAN Affects Expression [10]
Tumor necrosis factor receptor superfamily member 5 (CD40) OT5YU2XB TNR5_HUMAN Increases Expression [55]
NF-kappa-B inhibitor alpha (NFKBIA) OTFT924M IKBA_HUMAN Increases Expression [122]
Integrin alpha-3 (ITGA3) OTBCH21D ITA3_HUMAN Affects Expression [10]
High mobility group protein B2 (HMGB2) OTGEGAOK HMGB2_HUMAN Affects Expression [10]
Ciliary neurotrophic factor receptor subunit alpha (CNTFR) OT3B1RGG CNTFR_HUMAN Affects Expression [10]
Adenylate kinase 4, mitochondrial (AK4) OTA0T02Q KAD4_HUMAN Affects Expression [10]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Increases Phosphorylation [123]
Dipeptidyl peptidase 4 (DPP4) OT16MVL9 DPP4_HUMAN Affects Expression [23]
Proteasome subunit beta type-4 (PSMB4) OTOJ9OHA PSB4_HUMAN Decreases Expression [49]
Glutathione S-transferase Mu 2 (GSTM2) OTG4WT05 GSTM2_HUMAN Increases Expression [124]
5-hydroxytryptamine receptor 1B (HTR1B) OTFV5HKZ 5HT1B_HUMAN Increases Expression [110]
Probable global transcription activator SNF2L1 (SMARCA1) OT0Y6PTU SMCA1_HUMAN Affects Expression [23]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Increases Phosphorylation [123]
Protein S100-A2 (S100A2) OTTGHJ1H S10A2_HUMAN Increases Expression [58]
Transcription initiation factor IIE subunit beta (GTF2E2) OTDHCCCR T2EB_HUMAN Affects Expression [10]
Neuroendocrine convertase 1 (PCSK1) OTPBRJ54 NEC1_HUMAN Affects Expression [23]
CCN family member 2 (CCN2) OTC39NSU CCN2_HUMAN Increases Expression [16]
Ephrin type-A receptor 2 (EPHA2) OTI6QNX2 EPHA2_HUMAN Affects Methylation [13]
Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) OT33XNZM PTN6_HUMAN Increases Expression [125]
Cellular retinoic acid-binding protein 2 (CRABP2) OTY01V9G RABP2_HUMAN Affects Expression [10]
2'-5'-oligoadenylate synthase 2 (OAS2) OT64CCTM OAS2_HUMAN Increases Expression [16]
Cellular retinoic acid-binding protein 1 (CRABP1) OTISDG5X RABP1_HUMAN Affects Expression [10]
Peroxiredoxin-6 (PRDX6) OTS8KC8A PRDX6_HUMAN Affects Methylation [13]
Flavin reductase (BLVRB) OTHCFN2C BLVRB_HUMAN Affects Expression [10]
Peroxiredoxin-5, mitochondrial (PRDX5) OTUEKZ18 PRDX5_HUMAN Increases Expression [47]
M-phase inducer phosphatase 3 (CDC25C) OTPQI71S MPIP3_HUMAN Decreases Expression [21]
Tyrosine-protein kinase receptor UFO (AXL) OTKA2SUX UFO_HUMAN Affects Expression [10]
Translocator protein (TSPO) OTSU7ESK TSPO_HUMAN Affects Expression [10]
Sorcin (SRI) OT4R3EAC SORCN_HUMAN Affects Methylation [13]
Homeobox protein Hox-D3 (HOXD3) OTBUZ35T HXD3_HUMAN Increases Expression [126]
Homeobox protein Hox-A11 (HOXA11) OT42C4HF HXA11_HUMAN Increases Expression [110]
CAMPATH-1 antigen (CD52) OT02LDQN CD52_HUMAN Affects Expression [10]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Decreases Activity [127]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Increases Expression [101]
Protein S100-A11 (S100A11) OTI57KDN S10AB_HUMAN Affects Methylation [128]
C-C chemokine receptor type 7 (CCR7) OTHFUOYE CCR7_HUMAN Affects Expression [10]
CD70 antigen (CD70) OTHB2AL1 CD70_HUMAN Affects Expression [10]
T-lymphocyte activation antigen CD80 (CD80) OTJBLUQE CD80_HUMAN Increases Expression [55]
Protein S100-A5 (S100A5) OTCGGL6K S10A5_HUMAN Increases Expression [58]
Protein S100-A3 (S100A3) OTVIZJ2R S10A3_HUMAN Increases Expression [58]
DNA replication licensing factor MCM4 (MCM4) OT19PNNG MCM4_HUMAN Affects Methylation [13]
DNA replication licensing factor MCM5 (MCM5) OTAHLB62 MCM5_HUMAN Affects Methylation [13]
DNA replication licensing factor MCM7 (MCM7) OT6FXC6K MCM7_HUMAN Affects Methylation [13]
Syndecan-2 (SDC2) OTEEHY1D SDC2_HUMAN Affects Expression [23]
Cannabinoid receptor 2 (CNR2) OTYP9P43 CNR2_HUMAN Increases Expression [115]
Replication factor C subunit 4 (RFC4) OTWALD2R RFC4_HUMAN Affects Methylation [13]
Large ribosomal subunit protein eL22 (RPL22) OTVCN8K0 RL22_HUMAN Affects Methylation [13]
Pro-adrenomedullin (ADM) OT7T0TA4 ADML_HUMAN Affects Expression [10]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Affects Expression [23]
Mu-type opioid receptor (OPRM1) OT16AAT8 OPRM_HUMAN Increases Expression [115]
Apelin receptor (APLNR) OT8585HU APJ_HUMAN Affects Expression [10]
Thrombospondin-4 (THBS4) OTA1T9KK TSP4_HUMAN Affects Expression [10]
Tyrosine-protein kinase receptor Tie-1 (TIE1) OTBTL3PN TIE1_HUMAN Affects Expression [10]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Affects Expression [10]
Transcription factor SOX-18 (SOX18) OTPUMHWA SOX18_HUMAN Affects Expression [10]
Transcription factor SOX-11 (SOX11) OT4LG7LA SOX11_HUMAN Affects Expression [10]
Myosin-11 (MYH11) OTVNVWY3 MYH11_HUMAN Affects Expression [10]
Transcription factor 7 (TCF7) OT1ID822 TCF7_HUMAN Decreases Expression [118]
Large ribosomal subunit protein uL4 (RPL4) OTTYJB0X RL4_HUMAN Affects Methylation [13]
Serpin B5 (SERPINB5) OTSMXQRJ SPB5_HUMAN Decreases Methylation [129]
Amiloride-sensitive sodium channel subunit alpha (SCNN1A) OTE2KVZV SCNNA_HUMAN Affects Expression [10]
Peroxisome proliferator-activated receptor gamma (PPARG) OTHMARHO PPARG_HUMAN Increases Expression [122]
Squalene synthase (FDFT1) OTGDISIT FDFT_HUMAN Affects Expression [10]
Breast cancer type 1 susceptibility protein (BRCA1) OT5BN6VH BRCA1_HUMAN Affects Localization [53]
Stress-70 protein, mitochondrial (HSPA9) OT4TMVS9 GRP75_HUMAN Increases Expression [49]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Decreases Methylation [130]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST) OT39PDMS OST48_HUMAN Affects Methylation [13]
Interleukin-6 receptor subunit beta (IL6ST) OT1N9C70 IL6RB_HUMAN Increases Expression [131]
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) OTQOUHVK CEAM6_HUMAN Increases Expression [97]
Interferon alpha-inducible protein 27, mitochondrial (IFI27) OTI2XGIT IFI27_HUMAN Increases Expression [16]
DNA mismatch repair protein Mlh1 (MLH1) OTG5XDD8 MLH1_HUMAN Increases Expression [132]
Signal transducer and activator of transcription 3 (STAT3) OTAAGKYZ STAT3_HUMAN Decreases Expression [17]
Melanocyte protein PMEL (PMEL) OTCDDHHM PMEL_HUMAN Affects Expression [10]
Cyclin-F (CCNF) OTJFVU43 CCNF_HUMAN Decreases Expression [21]
Nociceptin receptor (OPRL1) OTSN4PCR OPRX_HUMAN Affects Expression [10]
Leptin (LEP) OT5Q7ODW LEP_HUMAN Increases Expression [30]
B-cell lymphoma 6 protein (BCL6) OTQAWWO1 BCL6_HUMAN Affects Expression [10]
Peripherin (PRPH) OT6VUH78 PERI_HUMAN Affects Expression [10]
Mitogen-activated protein kinase kinase kinase 8 (MAP3K8) OTOZTA1F M3K8_HUMAN Decreases Expression [61]
C-C chemokine receptor type 2 (CCR2) OTQ7T10J CCR2_HUMAN Increases Expression [16]
Tetraspanin-7 (TSPAN7) OTE4DJ79 TSN7_HUMAN Affects Expression [10]
T-lymphocyte activation antigen CD86 (CD86) OTJCSBPC CD86_HUMAN Increases Expression [55]
Cyclin-dependent kinase inhibitor 2A (CDKN2A) OTN0ZWAE CDN2A_HUMAN Decreases Methylation [133]
Cyclin-dependent kinase 4 inhibitor B (CDKN2B) OTAG24N1 CDN2B_HUMAN Decreases Methylation [134]
C-X-C motif chemokine 5 (CXCL5) OTZOUPCA CXCL5_HUMAN Increases Expression [72]
Netrin receptor DCC (DCC) OT2C1SHW DCC_HUMAN Increases Expression [135]
DNA mismatch repair protein Msh2 (MSH2) OT10H1AB MSH2_HUMAN Increases Expression [132]
Melanoma-associated antigen 1 (MAGEA1) OTXAO193 MAGA1_HUMAN Decreases Methylation [136]
Melanoma-associated antigen 2 (MAGEA2) OTQ0YOTY MAGA2_HUMAN Increases Expression [16]
Melanoma-associated antigen 3 (MAGEA3) OTW3Y5M4 MAGA3_HUMAN Increases Expression [55]
Melanoma-associated antigen 4 (MAGEA4) OTGP9SD0 MAGA4_HUMAN Increases Expression [55]
Melanoma-associated antigen 6 (MAGEA6) OTI8S0O2 MAGA6_HUMAN Affects Expression [137]
Melanoma-associated antigen 8 (MAGEA8) OTXJLU73 MAGA8_HUMAN Increases Expression [16]
Melanoma-associated antigen 9 (MAGEA9) OTWGX2SD MAGA9_HUMAN Increases Expression [16]
Melanoma-associated antigen 10 (MAGEA10) OTI4KPYB MAGAA_HUMAN Increases Expression [16]
Melanoma-associated antigen 12 (MAGEA12) OT8ULELL MAGAC_HUMAN Increases Expression [16]
Tyrosine-protein phosphatase non-receptor type 9 (PTPN9) OTNAR1I2 PTN9_HUMAN Decreases Expression [21]
Tyrosine-protein kinase SYK (SYK) OTQID87L KSYK_HUMAN Affects Expression [23]
Homeobox protein Nkx-2.1 (NKX2-1) OTCMEJTA NKX21_HUMAN Increases Expression [138]
ATP-binding cassette sub-family G member 1 (ABCG1) OT5BG6MK ABCG1_HUMAN Affects Expression [10]
Chemerin-like receptor 2 (CMKLR2) OTDNO0SL CML2_HUMAN Affects Expression [10]
5-hydroxytryptamine receptor 3A (HTR3A) OTAIV1AK 5HT3A_HUMAN Affects Expression [10]
Radiation-inducible immediate-early gene IEX-1 (IER3) OTZJI5FZ IEX1_HUMAN Increases Expression [111]
Rap1 GTPase-activating protein 1 (RAP1GAP) OTC31ONQ RPGP1_HUMAN Increases Expression [123]
Homeobox protein CDX-1 (CDX1) OTOHTMJE CDX1_HUMAN Increases Expression [97]
Large ribosomal subunit protein eL29 (RPL29) OTUFIBJL RL29_HUMAN Affects Expression [10]
Neuronal pentraxin-2 (NPTX2) OT3SSJDP NPTX2_HUMAN Affects Expression [10]
Inward rectifier potassium channel 4 (KCNJ4) OTZ2F6VR KCNJ4_HUMAN Affects Expression [10]
Glioma pathogenesis-related protein 1 (GLIPR1) OT0FGQK7 GLIP1_HUMAN Affects Methylation [139]
Stromal cell-derived factor 1 (CXCL12) OT2QX5LL SDF1_HUMAN Increases Expression [140]
Tissue factor pathway inhibitor 2 (TFPI2) OTZCRWOR TFPI2_HUMAN Increases Expression [141]
Leptin receptor (LEPR) OT9H7G0C LEPR_HUMAN Decreases Expression [142]
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PPP3CC) OT0AQD93 PP2BC_HUMAN Affects Expression [10]
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PIK3CG) OT3FAU4Y PK3CG_HUMAN Increases Expression [58]
Sodium/hydrogen exchanger 3 (SLC9A3) OTZ7PFVT SL9A3_HUMAN Increases Expression [16]
Guided entry of tail-anchored proteins factor CAMLG (CAMLG) OTTSRY39 CAMLG_HUMAN Affects Expression [10]
MAP kinase-activated protein kinase 2 (MAPKAPK2) OT460SBO MAPK2_HUMAN Affects Methylation [13]
Beta-arrestin-1 (ARRB1) OT2NJS37 ARRB1_HUMAN Affects Expression [10]
Inositol polyphosphate 1-phosphatase (INPP1) OTHSJCRQ INPP_HUMAN Affects Expression [10]
Centromere protein F (CENPF) OT7AG0SW CENPF_HUMAN Decreases Expression [21]
Alanine--tRNA ligase, cytoplasmic (AARS1) OTW8D813 SYAC_HUMAN Affects Expression [10]
CCAAT/enhancer-binding protein delta (CEBPD) OTNBIPMY CEBPD_HUMAN Affects Methylation [143]
Bis(5'-adenosyl)-triphosphatase (FHIT) OTGWBSLA FHIT_HUMAN Affects Methylation [144]
Selenide, water dikinase 1 (SEPHS1) OTZ19I59 SPS1_HUMAN Affects Expression [10]
Selenoprotein P (SELENOP) OT02B8IR SEPP1_HUMAN Affects Expression [23]
Double-strand break repair protein MRE11 (MRE11) OTGU8TZM MRE11_HUMAN Affects Localization [53]
LIM/homeobox protein Lhx2 (LHX2) OTK61NP8 LHX2_HUMAN Affects Expression [10]
PDZ and LIM domain protein 4 (PDLIM4) OT23LZYY PDLI4_HUMAN Affects Methylation [145]
Max-interacting protein 1 (MXI1) OTUQ9E0D MXI1_HUMAN Affects Expression [10]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10) OT4PXBTA TNF10_HUMAN Increases Expression [127]
Biotin--protein ligase (HLCS) OTPDUX30 BPL1_HUMAN Increases Expression [146]
Ras association domain-containing protein 2 (RASSF2) OT2JHDO4 RASF2_HUMAN Affects Expression [147]
Sodium/potassium-transporting ATPase subunit alpha-2 (ATP1A2) OTCF8OWW AT1A2_HUMAN Affects Expression [10]
Ras-related protein Rab-7a (RAB7A) OTBSPWMQ RAB7A_HUMAN Affects Expression [10]
Dual specificity protein phosphatase 3 (DUSP3) OTPJX9B4 DUS3_HUMAN Affects Expression [10]
N-acylglucosamine 2-epimerase (RENBP) OT8P1FP6 RENBP_HUMAN Affects Expression [10]
C-C chemokine receptor type 4 (CCR4) OT68KZ9B CCR4_HUMAN Affects Expression [23]
Chloride channel protein ClC-Ka (CLCNKA) OT7Q0RI9 CLCKA_HUMAN Affects Expression [10]
G-protein coupled receptor 143 (GPR143) OTWUA2AV GP143_HUMAN Decreases Expression [58]
Transketolase-like protein 1 (TKTL1) OTPP3M35 TKTL1_HUMAN Increases Expression [66]
Calponin-1 (CNN1) OTVPG39Z CNN1_HUMAN Affects Expression [10]
Serine/threonine-protein kinase Nek2 (NEK2) OT1H27HO NEK2_HUMAN Decreases Expression [21]
Rho-related GTP-binding protein RhoN (RND2) OT98M6UI RND2_HUMAN Affects Expression [10]
Importin subunit alpha-1 (KPNA2) OTU7FOE6 IMA1_HUMAN Affects Expression [10]
Tyrosine-protein kinase JAK3 (JAK3) OTQ8QW2L JAK3_HUMAN Decreases Expression [14]
DNA mismatch repair protein Msh6 (MSH6) OT46FP09 MSH6_HUMAN Increases Expression [18]
Kinesin-like protein KIF11 (KIF11) OTHRGLCQ KIF11_HUMAN Affects Expression [10]
Tricarboxylate transport protein, mitochondrial (SLC25A1) OTIDXQ9F TXTP_HUMAN Increases Expression [148]
Death-associated protein kinase 1 (DAPK1) OTNCNUCO DAPK1_HUMAN Increases Expression [149]
AP-3 complex subunit mu-2 (AP3M2) OT614AGJ AP3M2_HUMAN Affects Expression [10]
E3 ubiquitin-protein ligase TTC3 (TTC3) OTTR9WUC TTC3_HUMAN Affects Expression [10]
Calcipressin-1 (RCAN1) OT1MVXC7 RCAN1_HUMAN Affects Expression [10]
Phospholipase A and acyltransferase 3 (PLAAT3) OTVXXJ5K PLAT3_HUMAN Affects Expression [10]
Ataxin-3 (ATXN3) OTJVVGKT ATX3_HUMAN Affects Expression [10]
Mismatch repair endonuclease PMS2 (PMS2) OTNLWTMI PMS2_HUMAN Increases Expression [18]
Voltage-dependent L-type calcium channel subunit beta-3 (CACNB3) OTP30DIU CACB3_HUMAN Affects Expression [10]
Adenylate kinase 2, mitochondrial (AK2) OTZG3X2H KAD2_HUMAN Affects Expression [10]
Epithelial membrane protein 3 (EMP3) OTODMJ1D EMP3_HUMAN Affects Expression [10]
Microfibrillar-associated protein 2 (MFAP2) OTMHVBTV MFAP2_HUMAN Affects Expression [23]
GTP-binding protein RAD (RRAD) OTW2O4GD RAD_HUMAN Affects Expression [150]
Exportin-2 (CSE1L) OTV2X99A XPO2_HUMAN Affects Expression [10]
Thyroxine 5-deiodinase (DIO3) OTNTITOT IOD3_HUMAN Increases Expression [151]
Proteinase-activated receptor 2 (F2RL1) OTMRMJ8N PAR2_HUMAN Affects Expression [23]
Growth/differentiation factor 10 (GDF10) OTEVXGJ7 GDF10_HUMAN Increases Expression [152]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Increases Cleavage [56]
Caspase-6 (CASP6) OTXLD3EC CASP6_HUMAN Increases Expression [59]
Cadherin-8 (CDH8) OTS3SRZ6 CADH8_HUMAN Affects Expression [23]
Cadherin-11 (CDH11) OTIZKPTF CAD11_HUMAN Decreases Expression [85]
Cadherin-13 (CDH13) OTD2CYM5 CAD13_HUMAN Decreases Methylation [64]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Affects Expression [10]
Integrin alpha-1 (ITGA1) OTDITIST ITA1_HUMAN Affects Methylation [153]
Protein ripply3 (RIPPLY3) OT1HK35I DSCR6_HUMAN Affects Expression [10]
Claudin-2 (CLDN2) OTRF3D6Y CLD2_HUMAN Increases Expression [97]
Inhibin beta E chain (INHBE) OTOI2NYG INHBE_HUMAN Affects Expression [10]
Histone H2B type 1-D (H2BC5) OTXDTDHN H2B1D_HUMAN Affects Expression [10]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) OTOWDUNT PTEN_HUMAN Decreases Methylation [154]
Cyclin-dependent kinases regulatory subunit 1 (CKS1B) OTNUPLUJ CKS1_HUMAN Affects Methylation [13]
C-X-C chemokine receptor type 4 (CXCR4) OTUFSBX2 CXCR4_HUMAN Affects Expression [23]
Somatostatin (SST) OTY75GQH SMS_HUMAN Affects Methylation [155]
Lysozyme C (LYZ) OTD7H0G6 LYSC_HUMAN Decreases Methylation [156]
Beta-2-microglobulin (B2M) OTDWN6NX B2MG_HUMAN Increases Expression [49]
NPC intracellular cholesterol transporter 2 (NPC2) OTE9UEJC NPC2_HUMAN Affects Expression [10]
Ras-related protein R-Ras2 (RRAS2) OT83NCEB RRAS2_HUMAN Affects Expression [10]
Thymosin beta-4 (TMSB4X) OT9HPLP3 TYB4_HUMAN Affects Methylation [13]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Affects Expression [10]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Increases Expression [157]
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (POLR2L) OTSSOMUP RPAB5_HUMAN Affects Expression [10]
Peptidyl-prolyl cis-trans isomerase A (PPIA) OTHJMWQQ PPIA_HUMAN Decreases Expression [49]
Transcription elongation factor SPT4 (SUPT4H1) OTB3UCTB SPT4H_HUMAN Affects Expression [10]
Tropomyosin alpha-4 chain (TPM4) OTN4YLYR TPM4_HUMAN Decreases Expression [49]
Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B) OT8CMPB2 FKB1B_HUMAN Affects Expression [23]
Casein kinase II subunit alpha (CSNK2A1) OT9T8WQM CSK21_HUMAN Increases Expression [90]
Contactin-associated protein 1 (CNTNAP1) OT5Y03EU CNTP1_HUMAN Affects Expression [10]
Cancer/testis antigen 1 (CTAG1B) OTIQGW6U CTG1B_HUMAN Increases Expression [158]
Claudin-10 (CLDN10) OT2CVAKY CLD10_HUMAN Affects Expression [10]
CMP-sialic acid transporter (SLC35A1) OTPWOOVA S35A1_HUMAN Affects Expression [10]
Cyclin-A1 (CCNA1) OTX4HD45 CCNA1_HUMAN Affects Expression [66]
Iroquois-class homeodomain protein IRX-6 (IRX6) OTL79R2K IRX6_HUMAN Affects Expression [10]
Iroquois-class homeodomain protein IRX-4 (IRX4) OT0TV6WK IRX4_HUMAN Affects Expression [66]
Iroquois-class homeodomain protein IRX-3 (IRX3) OTLJ48FG IRX3_HUMAN Affects Expression [10]
DNA-dependent protein kinase catalytic subunit (PRKDC) OTJVS4EG PRKDC_HUMAN Affects Methylation [13]
Sushi repeat-containing protein SRPX (SRPX) OT5B9LXS SRPX_HUMAN Affects Expression [10]
ETS-related transcription factor Elf-3 (ELF3) OTUTLEQO ELF3_HUMAN Affects Expression [10]
Interleukin-13 receptor subunit alpha-1 (IL13RA1) OT59OYXP I13R1_HUMAN Increases Expression [159]
C-C motif chemokine 20 (CCL20) OTUCJY4N CCL20_HUMAN Increases Expression [16]
Metallothionein-1H (MT1H) OT0MVBM6 MT1H_HUMAN Affects Expression [10]
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) OTRWGNBF LACTB_HUMAN Affects Expression [10]
Fibulin-2 (FBLN2) OTEHR7N7 FBLN2_HUMAN Affects Expression [10]
Forkhead box protein O4 (FOXO4) OT90X9LN FOXO4_HUMAN Affects Expression [10]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Affects Expression [10]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B) OTSFVC82 2ABB_HUMAN Affects Expression [10]
Fanconi anemia group C protein (FANCC) OTTIDM3P FANCC_HUMAN Affects Expression [10]
Clathrin heavy chain 1 (CLTC) OTBFASMA CLH1_HUMAN Affects Methylation [13]
E3 ubiquitin-protein ligase Mdm2 (MDM2) OTOVXARF MDM2_HUMAN Affects Expression [23]
Protein SET (SET) OTGYYQJO SET_HUMAN Increases Expression [49]
Transcription factor RelB (RELB) OTU3QYEF RELB_HUMAN Increases Expression [58]
Myosin regulatory light chain 2, atrial isoform (MYL7) OT7ZNDP4 MLRA_HUMAN Increases Expression [160]
Peripheral myelin protein 22 (PMP22) OTXWYWCZ PMP22_HUMAN Increases Expression [58]
Interferon-induced transmembrane protein 2 (IFITM2) OTAT6TI6 IFM2_HUMAN Affects Expression [10]
Large neutral amino acids transporter small subunit 1 (SLC7A5) OT2WPVXD LAT1_HUMAN Affects Expression [10]
DNA-binding protein SATB1 (SATB1) OTT7SUVW SATB1_HUMAN Affects Expression [23]
Zinc finger protein basonuclin-1 (BNC1) OTGJ5WUF BNC1_HUMAN Affects Expression [66]
Transgelin (TAGLN) OTAEZ0KP TAGL_HUMAN Affects Expression [10]
Contactin-2 (CNTN2) OTQG9W7C CNTN2_HUMAN Affects Expression [161]
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase , mitochondrial (ALDH6A1) OT8LCZCT MMSA_HUMAN Decreases Expression [21]
Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1) OT4Y9NQI MP2K1_HUMAN Increases Expression [58]
Cyclic AMP-responsive element-binding protein 5 (CREB5) OTJDUJPI CREB5_HUMAN Affects Expression [10]
A-kinase anchor protein 12 (AKAP12) OTCVRDDX AKA12_HUMAN Affects Methylation [162]
Antigen peptide transporter 1 (TAP1) OTJL27PW TAP1_HUMAN Affects Expression [10]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Affects Localization [111]
Protein kinase C delta type (PRKCD) OTSEH90E KPCD_HUMAN Affects Expression [10]
Homeobox protein engrailed-1 (EN1) OT2DKIDK HME1_HUMAN Increases Expression [110]
Proteasome activator complex subunit 1 (PSME1) OTDHLJWH PSME1_HUMAN Affects Expression [10]
Recombining binding protein suppressor of hairless (RBPJ) OTD7CUG0 SUH_HUMAN Affects Expression [10]
GA-binding protein subunit beta-1 (GABPB1) OTEXDEJN GABP1_HUMAN Affects Expression [10]
DNA repair protein RAD51 homolog 1 (RAD51) OTNVWGC1 RAD51_HUMAN Affects Localization [53]
Early activation antigen CD69 (CD69) OTGJHSVP CD69_HUMAN Affects Expression [23]
C-X-C motif chemokine 9 (CXCL9) OTMFVZKZ CXCL9_HUMAN Affects Methylation [62]
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B) OTOA8WU2 PDE4B_HUMAN Affects Expression [10]
Homeobox protein DLX-2 (DLX2) OTKC2DQ0 DLX2_HUMAN Increases Expression [16]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Increases Expression [56]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Decreases Expression [88]
Interleukin-10 receptor subunit beta (IL10RB) OT5AN6ZR I10R2_HUMAN Affects Expression [10]
Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (MGAT3) OTXI5X4T MGAT3_HUMAN Affects Expression [10]
Histone acetyltransferase p300 (EP300) OTL8QJDX EP300_HUMAN Affects Methylation [163]
Neuroblast differentiation-associated protein AHNAK (AHNAK) OT6KH1WG AHNK_HUMAN Affects Expression [10]
Small cell adhesion glycoprotein (SMAGP) OT57BZII SMAGP_HUMAN Affects Expression [10]
Bone marrow stromal antigen 2 (BST2) OTU4LCJV BST2_HUMAN Affects Expression [23]
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) OTZVUOOB FBLN3_HUMAN Affects Methylation [65]
Mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) OTM7V78U M4K2_HUMAN Affects Expression [10]
Tyrosine-protein kinase Mer (MERTK) OTWBRAJ6 MERTK_HUMAN Affects Expression [10]
Chromodomain-helicase-DNA-binding protein 3 (CHD3) OTDBU4F3 CHD3_HUMAN Affects Expression [10]
Ral guanine nucleotide dissociation stimulator (RALGDS) OTG36NI7 GNDS_HUMAN Affects Expression [23]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Increases Expression [164]
Tetraspanin-31 (TSPAN31) OT8WQ83R TSN31_HUMAN Affects Expression [10]
Interleukin-24 (IL24) OT4VUWH1 IL24_HUMAN Increases Expression [58]
Secretory phospholipase A2 receptor (PLA2R1) OTDXSLRA PLA2R_HUMAN Increases Expression [165]
PR domain zinc finger protein 2 (PRDM2) OT8L7CGX PRDM2_HUMAN Affects Expression [166]
Acetyl-CoA carboxylase 1 (ACACA) OT5CQPZY ACACA_HUMAN Affects Expression [10]
Oxysterols receptor LXR-alpha (NR1H3) OT54YZ9I NR1H3_HUMAN Affects Expression [10]
TAR DNA-binding protein 43 (TARDBP) OTVOSFWW TADBP_HUMAN Affects Expression [10]
Syntaxin-3 (STX3) OT4CIWLJ STX3_HUMAN Affects Expression [10]
Steroidogenic factor 1 (NR5A1) OTOULYR4 STF1_HUMAN Affects Methylation [167]
Serine-protein kinase ATM (ATM) OTQVOHLT ATM_HUMAN Decreases Methylation [168]
Bcl-2-interacting killer (BIK) OTTH1T3D BIK_HUMAN Increases Expression [169]
Phospholipase D1 (PLD1) OTMVUKW6 PLD1_HUMAN Affects Expression [23]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Affects Expression [56]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Affects Expression [56]
Neuronal membrane glycoprotein M6-b (GPM6B) OT8Q1582 GPM6B_HUMAN Affects Expression [10]
Sequestosome-1 (SQSTM1) OTGY5D5J SQSTM_HUMAN Affects Expression [10]
Oligodendrocyte transcription factor 2 (OLIG2) OTMCN6D3 OLIG2_HUMAN Affects Expression [10]
Serine/threonine-protein kinase ATR (ATR) OTH0OP1J ATR_HUMAN Increases Activity [170]
Four and a half LIM domains protein 1 (FHL1) OTN535SU FHL1_HUMAN Affects Methylation [13]
Ras and Rab interactor 1 (RIN1) OTPBROUD RIN1_HUMAN Increases Expression [10]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) OTXEE550 APR_HUMAN Affects Expression [10]
Krueppel-like factor 9 (KLF9) OTBFEJRQ KLF9_HUMAN Affects Expression [10]
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) OTGM06VJ IDI1_HUMAN Affects Expression [10]
Lysosome membrane protein 2 (SCARB2) OTN929M8 SCRB2_HUMAN Affects Expression [10]
Kelch-like ECH-associated protein 1 (KEAP1) OTFHOD0C KEAP1_HUMAN Increases Expression [171]
DNA repair-scaffolding protein (SPIDR) OTO1OII0 SPIDR_HUMAN Affects Expression [10]
Protein BTG3 (BTG3) OT9ANHVT BTG3_HUMAN Increases Expression [157]
Ensconsin (MAP7) OTVSSJ33 MAP7_HUMAN Affects Expression [10]
Endoplasmic reticulum membrane sensor NFE2L1 (NFE2L1) OT1QHOS2 NF2L1_HUMAN Affects Methylation [13]
Hypermethylated in cancer 1 protein (HIC1) OTI9TWY4 HIC1_HUMAN Increases Expression [172]
Helicase-like transcription factor (HLTF) OTRX2OSF HLTF_HUMAN Affects Methylation [162]
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) OTGQ2AOJ ITPR3_HUMAN Affects Expression [10]
Desmocollin-3 (DSC3) OTYG47F8 DSC3_HUMAN Affects Expression [173]
ELAV-like protein 3 (ELAVL3) OTI2VI8B ELAV3_HUMAN Increases Expression [16]
Interleukin-11 receptor subunit alpha (IL11RA) OTN6DBCJ I11RA_HUMAN Affects Expression [10]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Increases Expression [174]
Prostaglandin reductase 1 (PTGR1) OTMAR351 PTGR1_HUMAN Affects Expression [10]
Nuclear factor 1 X-type (NFIX) OT1DPZAE NFIX_HUMAN Decreases Expression [21]
Nuclear mitotic apparatus protein 1 (NUMA1) OTTKAVG4 NUMA1_HUMAN Decreases Expression [21]
Transmembrane protein 132D (TMEM132D) OTV6I4Z0 T132D_HUMAN Affects Expression [10]
Rho guanine nucleotide exchange factor 6 (ARHGEF6) OTN1ABGL ARHG6_HUMAN Affects Expression [10]
Nectin-1 (NECTIN1) OTTE5ZR6 NECT1_HUMAN Affects Expression [10]
Receptor-type tyrosine-protein phosphatase kappa (PTPRK) OTAP5AT3 PTPRK_HUMAN Affects Methylation [13]
Ribosomal protein S6 kinase alpha-2 (RPS6KA2) OTIOYUSU KS6A2_HUMAN Affects Expression [10]
Mitochondrial fission regulator 1 (MTFR1) OTLB1VFT MTFR1_HUMAN Affects Expression [10]
Delta(24)-sterol reductase (DHCR24) OTP301JW DHC24_HUMAN Affects Expression [10]
Disks large-associated protein 5 (DLGAP5) OTWCN39U DLGP5_HUMAN Affects Expression [10]
Synaptonemal complex protein 1 (SYCP1) OTWFV4KA SYCP1_HUMAN Affects Expression [137]
Monocyte to macrophage differentiation factor (MMD) OTB5I4OC PAQRB_HUMAN Affects Expression [10]
Transcription elongation factor A protein 2 (TCEA2) OT1OS9TY TCEA2_HUMAN Affects Expression [10]
Transforming growth factor-beta-induced protein ig-h3 (TGFBI) OTR443C5 BGH3_HUMAN Increases Expression [16]
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (INPP5J) OT8M7KWA PI5PA_HUMAN Affects Expression [10]
Myosin light chain kinase, smooth muscle (MYLK) OT78QB4A MYLK_HUMAN Affects Expression [23]
Ephrin-B3 (EFNB3) OT12WTXQ EFNB3_HUMAN Affects Expression [10]
Neuronal pentraxin-1 (NPTX1) OTKVHCV0 NPTX1_HUMAN Affects Expression [10]
Cystatin-M (CST6) OTZVHJTF CYTM_HUMAN Increases Expression [16]
Protein SSX1 (SSX1) OTZ7NRCY SSX1_HUMAN Increases Expression [55]
Protein SSX2 (SSX2) OT2Z6RLL SSX2_HUMAN Increases Expression [55]
Neuronatin (NNAT) OTNRLO7G NNAT_HUMAN Increases Expression [175]
Probable G-protein coupled receptor 162 (GPR162) OTK4LT3K GP162_HUMAN Decreases Expression [21]
Transcription factor NF-E2 45 kDa subunit (NFE2) OTLM94BI NFE2_HUMAN Affects Expression [10]
Nuclear factor interleukin-3-regulated protein (NFIL3) OTQH9HM3 NFIL3_HUMAN Affects Expression [10]
Fascin (FSCN1) OTTGIHTM FSCN1_HUMAN Affects Methylation [13]
Cyclin-dependent kinase inhibitor 3 (CDKN3) OTBE3H07 CDKN3_HUMAN Affects Expression [10]
Anti-Muellerian hormone type-2 receptor (AMHR2) OT95APPM AMHR2_HUMAN Affects Expression [10]
Dual specificity protein phosphatase 5 (DUSP5) OTH96RA7 DUS5_HUMAN Affects Expression [10]
Histone H3.1t (H3-4) OTY6ITYF H31T_HUMAN Decreases Methylation [176]
Glutaminyl-peptide cyclotransferase (QPCT) OT0TSHP4 QPCT_HUMAN Increases Expression [16]
Kynurenine--oxoglutarate transaminase 1 (KYAT1) OTRD3RUJ KAT1_HUMAN Affects Expression [10]
Phosphoenolpyruvate carboxykinase , mitochondrial (PCK2) OTJ8LX4N PCKGM_HUMAN Affects Expression [10]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Increases Expression [16]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) OTQYEXL2 F264_HUMAN Affects Expression [10]
Tumor protein D53 (TPD52L1) OTSA6U0I TPD53_HUMAN Affects Expression [10]
MHC class I polypeptide-related sequence A (MICA) OTPEIEAR MICA_HUMAN Affects Expression [10]
Leucine-rich repeat-containing protein 26 (LRRC26) OTXEFL76 LRC26_HUMAN Affects Expression [10]
A-kinase anchor protein SPHKAP (SPHKAP) OT5RHUYJ SPKAP_HUMAN Increases Expression [110]
Small G protein signaling modulator 1 (SGSM1) OTS2PWT4 SGSM1_HUMAN Affects Expression [10]
Transmembrane protein 44 (TMEM44) OTRUF467 TMM44_HUMAN Affects Expression [10]
tRNA (TRMT5) OTOAZBPD TRM5_HUMAN Affects Expression [10]
Echinoderm microtubule-associated protein-like 3 (EML3) OTYNMJXI EMAL3_HUMAN Affects Expression [10]
Protein PTHB1 (BBS9) OT23V9YF PTHB1_HUMAN Affects Expression [10]
Ankyrin repeat and death domain-containing protein 1A (ANKDD1A) OTPNBHZS AKD1A_HUMAN Affects Expression [10]
Neuritin-like protein (NRN1L) OT7HTDKK NRN1L_HUMAN Affects Expression [10]
Extracellular tyrosine-protein kinase PKDCC (PKDCC) OTVXJR26 PKDCC_HUMAN Affects Expression [10]
Rho GTPase-activating protein 29 (ARHGAP29) OT8JH4TY RHG29_HUMAN Affects Methylation [62]
Kelch-like protein 12 (KLHL12) OT671F2U KLH12_HUMAN Affects Expression [10]
Pleckstrin homology-like domain family A member 2 (PHLDA2) OTMV9DPP PHLA2_HUMAN Increases Expression [16]
PDZ and LIM domain protein 3 (PDLIM3) OTVXQC81 PDLI3_HUMAN Affects Expression [10]
Single-strand selective monofunctional uracil DNA glycosylase (SMUG1) OT2YIOCQ SMUG1_HUMAN Affects Expression [10]
OCIA domain-containing protein 2 (OCIAD2) OTSWB4SZ OCAD2_HUMAN Affects Expression [10]
Puratrophin-1 (PLEKHG4) OT3RBPFL PKHG4_HUMAN Affects Expression [10]
Immunoglobulin superfamily member 11 (IGSF11) OTQEG2X1 IGS11_HUMAN Affects Expression [10]
RILP-like protein 1 (RILPL1) OTW4LHU8 RIPL1_HUMAN Affects Expression [10]
Putative G antigen family E member 3 (PAGE2B) OTCM1AID GGEE3_HUMAN Increases Expression [16]
NHL repeat-containing protein 3 (NHLRC3) OTBI6YSN NHLC3_HUMAN Affects Expression [10]
RRP12-like protein (RRP12) OTQQAEH4 RRP12_HUMAN Affects Expression [10]
Transmembrane protein 31 (TMEM31) OTKDPZD4 TMM31_HUMAN Affects Expression [10]
Uncharacterized protein C6orf141 (C6ORF141) OTUS3SIQ CF141_HUMAN Affects Expression [10]
Secreted frizzled-related protein 5 (SFRP5) OTLCVVSH SFRP5_HUMAN Increases Expression [118]
Transcriptional protein SWT1 (SWT1) OTY4AFM1 SWT1_HUMAN Affects Expression [10]
Protein FAM162B (FAM162B) OTZ31RP5 F162B_HUMAN Affects Expression [10]
LINE-1 type transposase domain-containing protein 1 (L1TD1) OTB2W20Y LITD1_HUMAN Decreases Methylation [177]
KN motif and ankyrin repeat domain-containing protein 4 (KANK4) OT5WC0Q8 KANK4_HUMAN Affects Expression [10]
Coiled-coil domain-containing protein 18 (CCDC18) OT0S9DA2 CCD18_HUMAN Decreases Expression [21]
Collagen alpha-1(XIII) chain (COL13A1) OTM9IM6J CODA1_HUMAN Affects Expression [10]
NEDD4-binding protein 2-like 1 (N4BP2L1) OTEGV3GO N42L1_HUMAN Affects Expression [10]
Sterile alpha motif domain-containing protein 5 (SAMD5) OT95NRVS SAMD5_HUMAN Decreases Expression [21]
Cilia- and flagella-associated protein 95 (CFAP95) OTJE0DU1 CFA95_HUMAN Affects Expression [10]
Myomegalin (PDE4DIP) OTS15WNF MYOME_HUMAN Affects Expression [23]
Uncharacterized protein C1orf53 (C1ORF53) OTQTOA4D CA053_HUMAN Affects Expression [10]
Succinate dehydrogenase assembly factor 4, mitochondrial (SDHAF4) OTDXI4H8 SDHF4_HUMAN Affects Expression [10]
Transcription elongation regulator 1-like protein (TCERG1L) OTSBSCLF TCRGL_HUMAN Affects Expression [10]
Lysophospholipase-like protein 1 (LYPLAL1) OT8F2DCV LYPL1_HUMAN Affects Expression [10]
SH2 domain-containing adapter protein E (SHE) OTRE2YP8 SHE_HUMAN Affects Expression [10]
Tetratricopeptide repeat protein 23 (TTC23) OT0F3HCQ TTC23_HUMAN Affects Expression [10]
Transmembrane protein 42 (TMEM42) OTCG6EZ0 TMM42_HUMAN Affects Expression [10]
Cell division cycle-associated protein 2 (CDCA2) OTX8UF9J CDCA2_HUMAN Affects Expression [10]
E3 ubiquitin-protein ligase TRIM68 (TRIM68) OTHMDMOG TRI68_HUMAN Affects Expression [10]
Dual specificity protein phosphatase 13A (DUSP13B) OT044C50 DS13A_HUMAN Affects Expression [10]
Uncharacterized protein KIAA0930 (KIAA0930) OTVJ73LN K0930_HUMAN Affects Expression [10]
Tau-tubulin kinase 2 (TTBK2) OT90YSM5 TTBK2_HUMAN Affects Expression [23]
Proline-rich protein 5-like (PRR5L) OTQ1Z0OU PRR5L_HUMAN Affects Expression [10]
Ultra-long-chain fatty acid omega-hydroxylase (CYP4F22) OTMNPZQL CP4FN_HUMAN Affects Expression [10]
Receptor expression-enhancing protein 3 (REEP3) OTM7YVIE REEP3_HUMAN Decreases Expression [21]
Phostensin (PPP1R18) OT0JVGOZ PPR18_HUMAN Affects Expression [10]
Cdc42 effector protein 5 (CDC42EP5) OTQQDUCD BORG3_HUMAN Affects Expression [10]
Mitochondrial mRNA pseudouridine synthase RPUSD3 (RPUSD3) OTG2GBBV RUSD3_HUMAN Affects Expression [10]
Mediator of RNA polymerase II transcription subunit 27 (MED27) OT40PZ9R MED27_HUMAN Affects Expression [10]
Calcium/calmodulin-dependent protein kinase type 1B (PNCK) OT35ZL74 KCC1B_HUMAN Affects Expression [10]
Long-chain fatty acid transport protein 1 (SLC27A1) OTK03OZN S27A1_HUMAN Affects Expression [10]
Protein aurora borealis (BORA) OTV2ZPKP BORA_HUMAN Affects Expression [10]
Kv channel-interacting protein 4 (KCNIP4) OTB1BS0X KCIP4_HUMAN Increases Expression [16]
ADP-ribosylation factor-like protein 9 (ARL9) OTCP868V ARL9_HUMAN Affects Expression [10]
Progestin and adipoQ receptor family member 3 (PAQR3) OTTKJ9Y4 PAQR3_HUMAN Affects Expression [10]
Kelch-like protein 24 (KLHL24) OTWZSX5C KLH24_HUMAN Affects Expression [10]
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) OTV01EFP C1TM_HUMAN Affects Expression [10]
Chondroitin sulfate proteoglycan 4 (CSPG4) OTW2D6DE CSPG4_HUMAN Affects Expression [10]
Cytochrome P450 20A1 (CYP20A1) OTIUZ6CF CP20A_HUMAN Affects Expression [10]
Interleukin-27 receptor subunit alpha (IL27RA) OTSQBAKI I27RA_HUMAN Affects Expression [10]
Protein shisa-2 homolog (SHISA2) OT4GMTML SHSA2_HUMAN Affects Expression [10]
CD164 sialomucin-like 2 protein (CD164L2) OT0LZOPP C16L2_HUMAN Decreases Methylation [10]
GLIPR1-like protein 1 (GLIPR1L1) OTAEYBSN GPRL1_HUMAN Affects Expression [10]
Protein FAM131A (FAM131A) OTF4ASVY F131A_HUMAN Affects Expression [10]
Inactive serine protease PAMR1 (PAMR1) OT83ZH5U PAMR1_HUMAN Affects Expression [10]
Interleukin-20 receptor subunit beta (IL20RB) OTHFXK95 I20RB_HUMAN Affects Expression [10]
Rab11 family-interacting protein 1 (RAB11FIP1) OT0T71OW RFIP1_HUMAN Affects Expression [10]
Scavenger receptor class A member 5 (SCARA5) OTOVA96E SCAR5_HUMAN Affects Expression [10]
SPOC domain-containing protein 1 (SPOCD1) OTF4K46N SPOC1_HUMAN Affects Expression [10]
Zinc finger protein basonuclin-2 (BNC2) OTU22H9Z BNC2_HUMAN Affects Expression [10]
Differentially expressed in FDCP 8 homolog (DEF8) OTS93PPZ DEFI8_HUMAN Affects Expression [10]
FYVE, RhoGEF and PH domain-containing protein 5 (FGD5) OT5VIRP2 FGD5_HUMAN Affects Expression [10]
Transmembrane protein 91 (TMEM91) OT6AQNY8 TMM91_HUMAN Affects Expression [10]
Forkhead box protein I2 (FOXI2) OTFQ0E2X FOXI2_HUMAN Affects Expression [10]
TLC domain-containing protein 5 (TLCD5) OTRAIGA4 TLCD5_HUMAN Affects Expression [10]
Rho family-interacting cell polarization regulator 1 (RIPOR1) OT9IFXAX RIPR1_HUMAN Affects Expression [10]
Protein FAM43B (FAM43B) OTLND7C6 FA43B_HUMAN Affects Expression [10]
Uncharacterized protein C3orf62 (C3ORF62) OTWF8EEF CC062_HUMAN Decreases Expression [21]
8-oxo-dGDP phosphatase NUDT18 (NUDT18) OT03IQA5 NUD18_HUMAN Affects Expression [10]
Acyl-CoA dehydrogenase family member 11 (ACAD11) OT3T9HAX ACD11_HUMAN Affects Expression [10]
MOB kinase activator 3C (MOB3C) OT2OFNGF MOB3C_HUMAN Affects Expression [10]
Centromere protein U (CENPU) OTQ4TZRS CENPU_HUMAN Affects Expression [10]
Ribosomal protein eS27-like (RPS27L) OTZWHU0N RS27L_HUMAN Affects Expression [10]
Probable ATP-dependent RNA helicase DDX46 (DDX46) OTB2X9TO DDX46_HUMAN Affects Expression [10]
Rho-related GTP-binding protein RhoU (RHOU) OTERIAD4 RHOU_HUMAN Affects Expression [10]
DET1 homolog (DET1) OTHYSDX3 DET1_HUMAN Affects Expression [10]
Synaptotagmin-13 (SYT13) OTG94RJ4 SYT13_HUMAN Affects Expression [10]
RAS guanyl-releasing protein 2 (RASGRP2) OTABVLVQ GRP2_HUMAN Affects Expression [10]
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) OTE8GBUR RIR2B_HUMAN Increases Expression [178]
Endoplasmic reticulum metallopeptidase 1 (ERMP1) OT9CIEO2 ERMP1_HUMAN Affects Expression [10]
P antigen family member 2 (PAGE2) OTGBTZFE PAGE2_HUMAN Increases Expression [16]
Transmembrane channel-like protein 6 (TMC6) OTKH50J4 TMC6_HUMAN Affects Expression [10]
Polycystin-1-like protein 2 (PKD1L2) OTVDFDED PK1L2_HUMAN Affects Expression [10]
Protein ADM2 (ADM2) OTJVN41C ADM2_HUMAN Affects Expression [10]
HAUS augmin-like complex subunit 6 (HAUS6) OT7ZVR57 HAUS6_HUMAN Decreases Expression [21]
L-xylulose reductase (DCXR) OTYVXRXB DCXR_HUMAN Affects Expression [10]
Transmembrane protein 144 (TMEM144) OT66EYSR TM144_HUMAN Affects Expression [10]
Uncharacterized aarF domain-containing protein kinase 2 (ADCK2) OTWTAQLU ADCK2_HUMAN Affects Expression [10]
Centriolin (CNTRL) OTQI3VBA CNTRL_HUMAN Decreases Expression [21]
Phosphatidylinositol-glycan biosynthesis class W protein (PIGW) OTT9SMTF PIGW_HUMAN Affects Expression [10]
Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CAMK2N1) OTKCR5XL CK2N1_HUMAN Affects Expression [10]
Uncharacterized protein C11orf96 (C11ORF96) OTEQU0V7 CK096_HUMAN Affects Expression [10]
Nucleoplasmin-2 (NPM2) OT9JSU8L NPM2_HUMAN Decreases Methylation [64]
Retrotransposon-derived protein PEG10 (PEG10) OTWD2278 PEG10_HUMAN Affects Expression [23]
Suppressor APC domain-containing protein 2 (SAPCD2) OTXS0EXM SAPC2_HUMAN Affects Expression [10]
Centrosomal AT-AC splicing factor (CENATAC) OTBZ080L CATAC_HUMAN Affects Expression [10]
5'-nucleotidase domain-containing protein 3 (NT5DC3) OTRHBVM5 NT5D3_HUMAN Affects Expression [10]
Zinc finger protein castor homolog 1 (CASZ1) OTWJ2OR8 CASZ1_HUMAN Increases Expression [50]
Paraneoplastic antigen-like protein 8A (PNMA8A) OTO3F7B0 PNM8A_HUMAN Affects Expression [10]
Myb-related transcription factor, partner of profilin (MYPOP) OTXR94P3 MYPOP_HUMAN Affects Expression [10]
Lysosomal-associated transmembrane protein 4B (LAPTM4B) OTTV150J LAP4B_HUMAN Affects Expression [10]
Probable D-lactate dehydrogenase, mitochondrial (LDHD) OTTKLJWP LDHD_HUMAN Affects Expression [10]
HORMA domain-containing protein 1 (HORMAD1) OT7DR5T2 HORM1_HUMAN Affects Expression [10]
Leucine-rich repeat-containing protein 28 (LRRC28) OTFTT6VN LRC28_HUMAN Affects Expression [10]
Centrosomal protein of 57 kDa (CEP57) OTPOHLIX CEP57_HUMAN Decreases Expression [21]
Enoyl-CoA hydratase domain-containing protein 2, mitochondrial (ECHDC2) OTL0DWCO ECHD2_HUMAN Affects Expression [10]
Transforming growth factor beta activator LRRC33 (NRROS) OT9WNOKY LRC33_HUMAN Increases Expression [110]
Na(+)/citrate cotransporter (SLC13A5) OTPH1TA7 S13A5_HUMAN Affects Expression [10]
Complement C1q-like protein 4 (C1QL4) OT9L6DLK C1QL4_HUMAN Affects Expression [10]
Interferon lambda receptor 1 (IFNLR1) OTWWWK45 INLR1_HUMAN Affects Expression [10]
ELKS/Rab6-interacting/CAST family member 1 (ERC1) OTYBGGNO RB6I2_HUMAN Affects Expression [10]
Neuronal PAS domain-containing protein 4 (NPAS4) OTA3HH6W NPAS4_HUMAN Increases Expression [16]
CREB3 regulatory factor (CREBRF) OT2GK1HI CRERF_HUMAN Affects Expression [10]
Adipocyte enhancer-binding protein 1 (AEBP1) OTBI1RZ6 AEBP1_HUMAN Affects Expression [23]
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) OTMOGNCV ANKY2_HUMAN Affects Expression [10]
LIX1-like protein (LIX1L) OTAK119S LIX1L_HUMAN Affects Expression [10]
Protein AHNAK2 (AHNAK2) OTD2X4BX AHNK2_HUMAN Affects Expression [10]
Extracellular sulfatase Sulf-2 (SULF2) OTIXMUVL SULF2_HUMAN Affects Expression [10]
SURP and G-patch domain-containing protein 2 (SUGP2) OTPUUJYX SUGP2_HUMAN Affects Expression [10]
Chromatin complexes subunit BAP18 (C17ORF49) OTKPULAA BAP18_HUMAN Affects Expression [10]
Kelch-like protein 7 (KLHL7) OT2OF1O8 KLHL7_HUMAN Affects Expression [10]
Kelch domain-containing protein 8B (KLHDC8B) OTKP6LCR KLD8B_HUMAN Affects Expression [10]
E3 ubiquitin-protein ligase TRIM22 (TRIM22) OTJBLG5R TRI22_HUMAN Increases Expression [16]
Mucolipin-2 (MCOLN2) OTU3V04B MCLN2_HUMAN Affects Expression [10]
Adhesion G-protein coupled receptor G2 (ADGRG2) OTPAD5S1 AGRG2_HUMAN Affects Expression [10]
FMR1 neighbor protein (FMR1NB) OT5IC2M2 FMR1N_HUMAN Increases Expression [55]
Serine/threonine-protein kinase 11-interacting protein (STK11IP) OTLQ6P8R S11IP_HUMAN Affects Expression [10]
Ly6/PLAUR domain-containing protein 1 (LYPD1) OT0HSGML LYPD1_HUMAN Affects Expression [10]
Latent-transforming growth factor beta-binding protein 4 (LTBP4) OTC8WL2V LTBP4_HUMAN Affects Expression [10]
Metallothionein-1M (MT1M) OTVT8PLU MT1M_HUMAN Increases Expression [16]
Maturin (MTURN) OTEBJNVG MTURN_HUMAN Affects Expression [10]
Secreted frizzled-related protein 1 (SFRP1) OT0U9G41 SFRP1_HUMAN Increases Expression [76]
Probable hydrolase PNKD (PNKD) OT6G9UXN PNKD_HUMAN Affects Expression [10]
Kelch-like protein 36 (KLHL36) OT7XMTW8 KLH36_HUMAN Affects Expression [10]
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (HDDC3) OTIX7RRB MESH1_HUMAN Affects Expression [10]
3-oxoacyl- reductase (CBR4) OT43V4UN CBR4_HUMAN Affects Expression [10]
Actin filament-associated protein 1-like 2 (AFAP1L2) OTJBI0VN AF1L2_HUMAN Affects Expression [10]
SH2 domain-containing protein 3C (SH2D3C) OTAGXO0N SH2D3_HUMAN Affects Expression [10]
Ribonuclease P protein subunit p25-like protein (RPP25L) OTHZ3E6T RP25L_HUMAN Affects Expression [10]
Meiosis-specific with OB domain-containing protein (MEIOB) OTTX5TF0 MEIOB_HUMAN Affects Expression [10]
DNA damage-regulated autophagy modulator protein 1 (DRAM1) OTIJTXEN DRAM1_HUMAN Affects Expression [10]
Probable methyltransferase-like protein 25 (METTL25) OTOIZDY4 MET25_HUMAN Affects Expression [10]
Dynein light chain Tctex-type 5 (DYNLT5) OTDM1DWJ DYLT5_HUMAN Affects Expression [10]
Testis-specific Y-encoded-like protein 6 (TSPYL6) OTQFY184 TSYL6_HUMAN Increases Expression [16]
Probable transmembrane reductase CYB561D1 (CYB561D1) OTNFHIC3 C56D1_HUMAN Affects Expression [10]
Tudor domain-containing protein 5 (TDRD5) OTYSOQS0 TDRD5_HUMAN Affects Expression [10]
Fibronectin type III domain-containing protein 5 (FNDC5) OT5CSK9X FNDC5_HUMAN Affects Expression [10]
Mixed lineage kinase domain-like protein (MLKL) OTDSLC81 MLKL_HUMAN Affects Expression [10]
Phospholipid-transporting ATPase IG (ATP11C) OTKMV2K5 AT11C_HUMAN Affects Expression [10]
Inactive C-alpha-formylglycine-generating enzyme 2 (SUMF2) OT37I8JL SUMF2_HUMAN Affects Expression [10]
SID1 transmembrane family member 2 (SIDT2) OTU2L002 SIDT2_HUMAN Affects Expression [10]
Transmembrane protein 35B (TMEM35B) OTIL2CC7 TM35B_HUMAN Affects Expression [10]
Putative RNA-binding protein 15B (RBM15B) OTRJ9DT7 RB15B_HUMAN Affects Expression [10]
Putative methyltransferase NSUN7 (NSUN7) OTDTL9UE NSUN7_HUMAN Affects Expression [10]
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (LFNG) OTPSUBN2 LFNG_HUMAN Affects Expression [10]
F-box only protein 22 (FBXO22) OTEJ5MO0 FBX22_HUMAN Affects Expression [10]
DNA helicase B (HELB) OT769EC5 HELB_HUMAN Increases Expression [16]
RAD52 motif-containing protein 1 (RDM1) OTBSJEAG RDM1_HUMAN Affects Expression [10]
Motile sperm domain-containing protein 2 (MOSPD2) OTTN4NR7 MSPD2_HUMAN Affects Expression [10]
Putative aspartate aminotransferase, cytoplasmic 2 (GOT1L1) OTJTD6JA AATC2_HUMAN Increases Expression [16]
Tudor domain-containing protein 7 (TDRD7) OTK639ET TDRD7_HUMAN Affects Expression [10]
Rhox homeobox family member 1 (RHOXF1) OT3SC14T RHXF1_HUMAN Increases Expression [179]
Transcriptional repressor CTCFL (CTCFL) OTF1LUHX CTCFL_HUMAN Increases Expression [16]
Rieske domain-containing protein (RFESD) OTLYAJIB RFESD_HUMAN Affects Expression [10]
Spermatogenesis-associated protein 20 (SPATA20) OTWKX0AZ SPT20_HUMAN Affects Expression [10]
Protein NDNF (NDNF) OTCDL9PG NDNF_HUMAN Affects Expression [10]
Solute carrier family 7 member 14 (SLC7A14) OT07YJW4 S7A14_HUMAN Affects Expression [10]
Arrestin domain-containing protein 2 (ARRDC2) OTVEOXAG ARRD2_HUMAN Affects Expression [10]
Guanine nucleotide exchange factor for Rab-3A (RAB3IL1) OT18H5HD R3GEF_HUMAN Affects Expression [10]
Cilia- and flagella-associated protein 251 (CFAP251) OT0GKNAU CF251_HUMAN Increases Expression [16]
Mitochondria-eating protein (SPATA18) OTOEHTHU MIEAP_HUMAN Affects Expression [10]
Ecto-NOX disulfide-thiol exchanger 1 (ENOX1) OT4WOLA8 ENOX1_HUMAN Decreases Expression [21]
Cytoplasmic dynein 2 light intermediate chain 1 (DYNC2LI1) OT1X5YGJ DC2L1_HUMAN Affects Expression [10]
Neuropilin and tolloid-like protein 1 (NETO1) OTXP9A63 NETO1_HUMAN Increases Expression [16]
CDK5 and ABL1 enzyme substrate 1 (CABLES1) OTMN4XSX CABL1_HUMAN Affects Expression [10]
Protein phosphatase Slingshot homolog 3 (SSH3) OT83V0ZK SSH3_HUMAN Affects Expression [10]
Grainyhead-like protein 3 homolog (GRHL3) OT1V4ZEH GRHL3_HUMAN Affects Expression [10]
E3 ubiquitin-protein ligase SH3RF2 (SH3RF2) OT2IVOK4 SH3R2_HUMAN Decreases Expression [21]
Ankyrin repeat domain-containing protein 24 (ANKRD24) OTNFN0NB ANR24_HUMAN Affects Expression [10]
Folliculin-interacting protein 1 (FNIP1) OTB1CC41 FNIP1_HUMAN Affects Expression [10]
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) OTY829Z3 ABHD5_HUMAN Affects Expression [10]
GATOR1 complex protein NPRL2 (NPRL2) OTOB10MO NPRL2_HUMAN Affects Expression [10]
Cytosolic arginine sensor for mTORC1 subunit 1 (CASTOR1) OTYIH7WK CAST1_HUMAN Affects Expression [10]
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (PYROXD1) OTPGO23E PYRD1_HUMAN Affects Expression [10]
DEP domain-containing protein 1B (DEPDC1B) OTMVFOT1 DEP1B_HUMAN Affects Expression [10]
Pleckstrin homology-like domain family A member 1 (PHLDA1) OTFTWMIQ PHLA1_HUMAN Affects Expression [66]
Cohesin subunit SA-1 (STAG1) OT564IX4 STAG1_HUMAN Affects Expression [10]
Kelch repeat and BTB domain-containing protein 7 (KBTBD7) OT1NIRLK KBTB7_HUMAN Affects Expression [10]
DnaJ homolog subfamily A member 4 (DNAJA4) OTT7YCD2 DNJA4_HUMAN Increases Expression [16]
Gamma-secretase subunit APH-1B (APH1B) OTQHPTGC APH1B_HUMAN Affects Expression [10]
Uncharacterized protein C1orf54 (C1ORF54) OTXFDXKJ CA054_HUMAN Affects Expression [10]
DnaJ homolog subfamily B member 3 (DNAJB3) OTODJZY9 DNJB3_HUMAN Increases Expression [16]
Na(+)/dicarboxylate cotransporter 3 (SLC13A3) OTRDOV1Y S13A3_HUMAN Affects Expression [10]
Palladin (PALLD) OTZ2MUJZ PALLD_HUMAN Affects Expression [10]
DNA damage-binding protein 2 (DDB2) OTO8HVVB DDB2_HUMAN Affects Expression [10]
StAR-related lipid transfer protein 8 (STARD8) OTY9IAKW STAR8_HUMAN Affects Expression [10]
Hamartin (TSC1) OTFF4YZ7 TSC1_HUMAN Affects Expression [10]
Unconventional myosin-XVIIIa (MYO18A) OT2YPT7O MY18A_HUMAN Decreases Expression [21]
Rho GTPase-activating protein 45 (ARHGAP45) OTL86FEQ HMHA1_HUMAN Increases Expression [180]
Estrogen receptor beta (ESR2) OTXNR2WQ ESR2_HUMAN Decreases Expression [75]
Ras-like protein family member 10A (RASL10A) OTEXTN6I RSLAA_HUMAN Affects Expression [10]
Serine protease HTRA1 (HTRA1) OTR8ACBF HTRA1_HUMAN Increases Expression [181]
Prospero homeobox protein 1 (PROX1) OT68R6IO PROX1_HUMAN Increases Expression [182]
Hyaluronan synthase 2 (HAS2) OTTD3PAL HYAS2_HUMAN Affects Expression [23]
Neuronal cell adhesion molecule (NRCAM) OT80HHQ2 NRCAM_HUMAN Affects Expression [66]
Homeobox protein Hox-B13 (HOXB13) OTRMYHI9 HXB13_HUMAN Affects Expression [23]
Protein kinase C-binding protein NELL1 (NELL1) OTF3TX3N NELL1_HUMAN Affects Methylation [183]
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (INPP5D) OT7I3U0G SHIP1_HUMAN Affects Expression [10]
Kinesin-associated protein 3 (KIFAP3) OT450PAO KIFA3_HUMAN Affects Expression [10]
Phosphomannomutase 1 (PMM1) OTU0BW0Y PMM1_HUMAN Affects Expression [10]
Kallikrein-6 (KLK6) OTIEA234 KLK6_HUMAN Affects Expression [10]
BLOC-3 complex member HPS1 (HPS1) OTKS5I7T HPS1_HUMAN Affects Expression [23]
Sodium/iodide cotransporter (SLC5A5) OTU7E9G7 SC5A5_HUMAN Increases Expression [184]
Mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1) OT6FQ1K3 M4K1_HUMAN Affects Expression [10]
Solute carrier organic anion transporter family member 2A1 (SLCO2A1) OT3062CA SO2A1_HUMAN Increases Expression [67]
Rho guanine nucleotide exchange factor 2 (ARHGEF2) OTBQTFRT ARHG2_HUMAN Affects Expression [10]
Ribosomal RNA small subunit methyltransferase NEP1 (EMG1) OTFDX7HY NEP1_HUMAN Affects Expression [10]
Interferon regulatory factor 7 (IRF7) OTC1A2PQ IRF7_HUMAN Increases Expression [58]
Stathmin-2 (STMN2) OT0FUHLH STMN2_HUMAN Affects Expression [10]
Selenocysteine insertion sequence-binding protein 2-like (SECISBP2L) OTMSOLZU SBP2L_HUMAN Affects Expression [10]
Fetal and adult testis-expressed transcript protein (FATE1) OTPYXV64 FATE1_HUMAN Increases Expression [55]
Protein naked cuticle homolog 2 (NKD2) OTCYT3I6 NKD2_HUMAN Affects Expression [10]
Ankyrin repeat and BTB/POZ domain-containing protein 1 (ABTB1) OTKKPQJL ABTB1_HUMAN Affects Expression [10]
Transmembrane protein 54 (TMEM54) OTPQEFR0 TMM54_HUMAN Affects Expression [10]
Oxysterol-binding protein 2 (OSBP2) OTDGLB4J OSBP2_HUMAN Affects Expression [10]
Protein phosphatase 1 regulatory subunit 14A (PPP1R14A) OTQODWZB PP14A_HUMAN Affects Expression [10]
V-type proton ATPase subunit E 2 (ATP6V1E2) OTNNHL6G VATE2_HUMAN Affects Expression [10]
Antizyme inhibitor 2 (AZIN2) OT8OB7CG AZIN2_HUMAN Affects Expression [10]
Endothelial cell-selective adhesion molecule (ESAM) OTF518AI ESAM_HUMAN Increases Expression [16]
Interferon-stimulated gene 20 kDa protein (ISG20) OTCWRJJW ISG20_HUMAN Affects Expression [10]
Dapper homolog 3 (DACT3) OTSNQ55G DACT3_HUMAN Affects Expression [185]
Claudin-23 (CLDN23) OTN5RV40 CLD23_HUMAN Affects Expression [10]
Transmembrane protein 18 (TMEM18) OT05YQ1E TMM18_HUMAN Decreases Expression [21]
Solute carrier family 22 member 18 (SLC22A18) OT9C3KR4 S22AI_HUMAN Affects Expression [10]
Tripartite motif-containing protein 43 (TRIM43) OT6SKRF0 TRI43_HUMAN Increases Expression [16]
Transmembrane 4 L6 family member 18 (TM4SF18) OTDES2NC T4S18_HUMAN Affects Expression [10]
Collagen triple helix repeat-containing protein 1 (CTHRC1) OTV88X2G CTHR1_HUMAN Affects Expression [10]
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) OTBB799S ACSF2_HUMAN Affects Expression [10]
Optineurin (OPTN) OT2UXWH9 OPTN_HUMAN Affects Expression [10]
Leucine-rich repeat-containing protein 58 (LRRC58) OTJ9JMKX LRC58_HUMAN Affects Expression [10]
GTP-binding protein Rhes (RASD2) OTETA815 RHES_HUMAN Affects Expression [10]
Voltage-gated hydrogen channel 1 (HVCN1) OT4ALYU4 HVCN1_HUMAN Increases Expression [16]
FXYD domain-containing ion transport regulator 5 (FXYD5) OT81DIOD FXYD5_HUMAN Affects Expression [10]
Carboxymethylenebutenolidase homolog (CMBL) OT8H3S3G CMBL_HUMAN Affects Expression [10]
CAP-Gly domain-containing linker protein 3 (CLIP3) OTGJEGIB CLIP3_HUMAN Affects Expression [10]
Transmembrane 4 L6 family member 19 (TM4SF19) OTDG6Q3X T4S19_HUMAN Increases Expression [16]
Metalloendopeptidase OMA1, mitochondrial (OMA1) OT0JRVY7 OMA1_HUMAN Affects Expression [10]
Constitutive coactivator of peroxisome proliferator-activated receptor gamma (FAM120B) OTGYUFOJ F120B_HUMAN Affects Expression [10]
HSPB1-associated protein 1 (HSPBAP1) OTRYDAZX HBAP1_HUMAN Affects Expression [10]
P antigen family member 5 (PAGE5) OTN9NUH5 PAGE5_HUMAN Increases Expression [16]
Brevican core protein (BCAN) OTPVY3ZR PGCB_HUMAN Affects Expression [10]
Protein disulfide isomerase CRELD1 (CRELD1) OTBSPZFP CREL1_HUMAN Affects Expression [10]
Secreted frizzled-related protein 2 (SFRP2) OT8GZ0CA SFRP2_HUMAN Increases Expression [118]
Receptor expression-enhancing protein 6 (REEP6) OTY4FPO8 REEP6_HUMAN Affects Expression [10]
F-box/LRR-repeat protein 20 (FBXL20) OTVTR1KY FXL20_HUMAN Affects Expression [10]
Fatty acid hydroxylase domain-containing protein 2 (FAXDC2) OTRRS828 FXDC2_HUMAN Affects Expression [10]
SH2 domain-containing adapter protein D (SHD) OTGTHL5V SHD_HUMAN Affects Expression [10]
Vesicle-trafficking protein SEC22a (SEC22A) OTSAGTP6 SC22A_HUMAN Affects Expression [10]
Lysyl oxidase homolog 4 (LOXL4) OT6XY2JL LOXL4_HUMAN Increases Expression [16]
Coiled-coil domain-containing protein 136 (CCDC136) OTPOV391 CC136_HUMAN Affects Expression [10]
Protein maelstrom homolog (MAEL) OTZ2VU30 MAEL_HUMAN Increases Expression [16]
Golgi-associated RAB2 interactor protein 1B (GARIN1B) OTWPN527 GAR1B_HUMAN Affects Expression [10]
Protein FAM167A (FAM167A) OT9JF3JQ F167A_HUMAN Affects Expression [10]
Spermatogenesis-associated protein 17 (SPATA17) OT6SK923 SPT17_HUMAN Affects Expression [10]
Intraflagellar transport protein 74 homolog (IFT74) OTZBFEDD IFT74_HUMAN Affects Expression [23]
Myelin regulatory factor-like protein (MYRFL) OTVCXFLF MRFL_HUMAN Affects Expression [10]
Doublesex- and mab-3-related transcription factor B1 (DMRTB1) OT5A94KF DMRTB_HUMAN Increases Expression [16]
Coenzyme Q-binding protein COQ10 homolog A, mitochondrial (COQ10A) OT7IWAOI CQ10A_HUMAN Affects Expression [10]
TOX high mobility group box family member 2 (TOX2) OT7RZRVK TOX2_HUMAN Affects Expression [10]
Chloride intracellular channel protein 6 (CLIC6) OTFMSU5U CLIC6_HUMAN Affects Expression [10]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Increases Expression [17]
Kelch-like protein 5 (KLHL5) OTRDVST4 KLHL5_HUMAN Affects Expression [10]
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) OT1B19RU NED4L_HUMAN Decreases Expression [21]
Alsin (ALS2) OT8BAM04 ALS2_HUMAN Affects Expression [10]
Rho GTPase-activating protein 7 (DLC1) OTP8LMCR RHG07_HUMAN Affects Methylation [162]
Small integral membrane protein 14 (SMIM14) OT47IF19 SIM14_HUMAN Affects Expression [10]
Secretoglobin family 3A member 1 (SCGB3A1) OTIR98RB SG3A1_HUMAN Increases Expression [186]
1-aminocyclopropane-1-carboxylate synthase-like protein 1 (ACCS) OTHIHI9D 1A1L1_HUMAN Affects Expression [10]
Retinoid-binding protein 7 (RBP7) OT0J3CPT RET7_HUMAN Increases Expression [50]
Tribbles homolog 3 (TRIB3) OTG5OS7X TRIB3_HUMAN Affects Expression [10]
Pleckstrin homology domain-containing family F member 1 (PLEKHF1) OT9OL16U PKHF1_HUMAN Affects Expression [23]
Selenocysteine insertion sequence-binding protein 2 (SECISBP2) OTBXUURJ SEBP2_HUMAN Affects Expression [10]
Histone-lysine N-methyltransferase SETDB2 (SETDB2) OTBVVP9Q SETB2_HUMAN Affects Expression [10]
Mucin-4 (MUC4) OTLT11V1 MUC4_HUMAN Increases Expression [187]
Peroxisomal acyl-coenzyme A oxidase 2 (ACOX2) OT3VH359 ACOX2_HUMAN Affects Expression [10]
Protein kinase C-binding protein NELL2 (NELL2) OTS4MJZ7 NELL2_HUMAN Affects Expression [10]
Paired mesoderm homeobox protein 2B (PHOX2B) OT3SFR2O PHX2B_HUMAN Increases Expression [188]
G-protein coupled estrogen receptor 1 (GPER1) OTUK0TDC GPER1_HUMAN Decreases Methylation [10]
TSC22 domain family protein 3 (TSC22D3) OT03UM03 T22D3_HUMAN Affects Expression [10]
GTP-binding protein Rit2 (RIT2) OTSNYG0D RIT2_HUMAN Affects Expression [10]
Protein S100-A13 (S100A13) OT582SUS S10AD_HUMAN Affects Expression [10]
ETS-related transcription factor Elf-4 (ELF4) OT167PR5 ELF4_HUMAN Affects Expression [10]
Necdin (NDN) OTYBYJ82 NECD_HUMAN Increases Expression [16]
Selenide, water dikinase 2 (SEPHS2) OTTFXROR SPS2_HUMAN Affects Expression [10]
Krueppel-like factor 6 (KLF6) OTQY9S7F KLF6_HUMAN Affects Expression [10]
Cell division cycle-associated protein 3 (CDCA3) OTUI8QK3 CDCA3_HUMAN Affects Expression [10]
Homeobox protein CDX-2 (CDX2) OTCG4TSY CDX2_HUMAN Increases Expression [189]
Calcineurin B homologous protein 1 (CHP1) OTHTXN1A CHP1_HUMAN Affects Methylation [13]
Docking protein 1 (DOK1) OTGVRLW6 DOK1_HUMAN Increases Expression [16]
Metalloproteinase inhibitor 4 (TIMP4) OT8A68SW TIMP4_HUMAN Affects Expression [10]
Microsomal glutathione S-transferase 2 (MGST2) OT4UGTDO MGST2_HUMAN Affects Expression [10]
Neurturin (NRTN) OT4PAKUY NRTN_HUMAN Decreases Expression [21]
Copine-1 (CPNE1) OTH5YKSL CPNE1_HUMAN Affects Expression [10]
Protein SSX3 (SSX3) OTGJV5UZ SSX3_HUMAN Increases Expression [159]
Cbp/p300-interacting transactivator 1 (CITED1) OTUJQ3VL CITE1_HUMAN Increases Expression [16]
Growth/differentiation factor 15 (GDF15) OTWQN50N GDF15_HUMAN Affects Expression [23]
Ras-like protein family member 11B (RASL11B) OTHEVZS6 RSLBB_HUMAN Affects Expression [10]
17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14) OT0ETO72 DHB14_HUMAN Affects Expression [10]
ATP-dependent RNA helicase DDX50 (DDX50) OTUXH147 DDX50_HUMAN Affects Expression [10]
Fermitin family homolog 1 (FERMT1) OT626PBA FERM1_HUMAN Affects Expression [10]
Rhox homeobox family member 2 (RHOXF2) OTKQWLKZ RHXF2_HUMAN Increases Expression [179]
Dysbindin domain-containing protein 2 (DBNDD2) OT9RI580 DBND2_HUMAN Affects Expression [10]
Rho GTPase-activating protein 9 (ARHGAP9) OTJNHX96 RHG09_HUMAN Affects Expression [10]
La-related protein 6 (LARP6) OTUQ9QS9 LARP6_HUMAN Affects Expression [10]
Latexin (LXN) OTZQ2M6Y LXN_HUMAN Affects Expression [23]
Haloacid dehalogenase-like hydrolase domain-containing protein 3 (HDHD3) OTY4LG3Z HDHD3_HUMAN Affects Expression [10]
TERF1-interacting nuclear factor 2 (TINF2) OT861N2N TINF2_HUMAN Affects Expression [10]
DNA-directed RNA polymerase III subunit RPC7-like (POLR3GL) OT694B27 RPC7L_HUMAN Affects Expression [10]
Transmembrane protein 208 (TMEM208) OTMGH9OA TM208_HUMAN Affects Expression [10]
MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1) OTGBRJDQ MKNK1_HUMAN Affects Expression [10]
Coiled-coil domain-containing protein 28B (CCDC28B) OT1HFHN2 CC28B_HUMAN Affects Expression [10]
EF-hand domain-containing protein D1 (EFHD1) OTL5INE4 EFHD1_HUMAN Affects Expression [10]
Probable ATP-dependent RNA helicase DDX23 (DDX23) OTBJHS8C DDX23_HUMAN Affects Expression [10]
Methylthioribose-1-phosphate isomerase (MRI1) OTOP49DM MTNA_HUMAN Affects Expression [10]
Acireductone dioxygenase (ADI1) OT8IOD03 MTND_HUMAN Affects Expression [10]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) OTZ092ZJ THIC_HUMAN Affects Expression [10]
Transcription factor GATA-5 (GATA5) OTO81B63 GATA5_HUMAN Affects Expression [10]
Adenosine 5'-monophosphoramidase HINT2 (HINT2) OTW9GS0U HINT2_HUMAN Affects Expression [10]
TM2 domain-containing protein 1 (TM2D1) OTWA4YSR TM2D1_HUMAN Affects Expression [10]
Oxysterol-binding protein-related protein 10 (OSBPL10) OT0TFMBE OSB10_HUMAN Affects Expression [10]
Bardet-Biedl syndrome 2 protein (BBS2) OTPF9JIB BBS2_HUMAN Affects Expression [10]
Complement C1q tumor necrosis factor-related protein 6 (C1QTNF6) OT57EPQC C1QT6_HUMAN Affects Expression [10]
Serine/threonine-protein kinase PINK1, mitochondrial (PINK1) OT50NR57 PINK1_HUMAN Affects Expression [10]
Sperm protein associated with the nucleus on the X chromosome D (SPANXD) OTMM6ANB SPNXD_HUMAN Increases Expression [16]
Voltage-dependent calcium channel gamma-6 subunit (CACNG6) OT2PC1E1 CCG6_HUMAN Affects Expression [10]
Microtubule-associated proteins 1A/1B light chain 3C (MAP1LC3C) OTM4ECDK MLP3C_HUMAN Affects Expression [10]
Cell adhesion molecule 1 (CADM1) OTRWG9QS CADM1_HUMAN Affects Expression [190]
NF-kappa-B inhibitor zeta (NFKBIZ) OTU728KS IKBZ_HUMAN Affects Expression [10]
3'-5' exoribonuclease HELZ2 (HELZ2) OTM6HVO6 HELZ2_HUMAN Affects Expression [10]
Leucine-rich repeat-containing protein 2 (LRRC2) OTX6P291 LRRC2_HUMAN Affects Expression [23]
Tripartite motif-containing protein 54 (TRIM54) OTI49DD6 TRI54_HUMAN Decreases Methylation [10]
Disintegrin and metalloproteinase domain-containing protein 33 (ADAM33) OTRZVI77 ADA33_HUMAN Decreases Methylation [191]
FERM domain-containing protein 8 (FRMD8) OTTH5DUJ FRMD8_HUMAN Affects Expression [10]
Cytoplasmic polyadenylation element-binding protein 1 (CPEB1) OTLCXC6H CPEB1_HUMAN Affects Expression [23]
Oxysterol-binding protein-related protein 6 (OSBPL6) OT0NCUUA OSBL6_HUMAN Affects Expression [10]
E3 ubiquitin-protein ligase TRIM4 (TRIM4) OTLKQNKQ TRIM4_HUMAN Affects Expression [10]
182 kDa tankyrase-1-binding protein (TNKS1BP1) OTBIZECQ TB182_HUMAN Decreases Expression [21]
Nuclear distribution protein nudE-like 1 (NDEL1) OTAGFML5 NDEL1_HUMAN Affects Expression [10]
Nuclear RNA export factor 2 (NXF2) OTJS5KTH NXF2_HUMAN Increases Expression [55]
Cytochrome c oxidase assembly factor 1 homolog (COA1) OTHSX40F COA1_HUMAN Affects Expression [10]
Disintegrin and metalloproteinase domain-containing protein 19 (ADAM19) OTH88TXU ADA19_HUMAN Affects Expression [10]
Solute carrier family 22 member 4 (SLC22A4) OT4LOVI9 S22A4_HUMAN Increases Expression [68]
Ras-related protein Rab-6C (RAB6C) OTA66R5E RAB6C_HUMAN Increases Expression [192]
FXYD domain-containing ion transport regulator 6 (FXYD6) OTHOQXGF FXYD6_HUMAN Affects Expression [10]
Transmembrane protein 222 (TMEM222) OTWFLPK2 TM222_HUMAN Affects Expression [10]
Homeobox protein aristaless-like 4 (ALX4) OTNS9A29 ALX4_HUMAN Decreases Methylation [193]
Stathmin-4 (STMN4) OT7ZUKW6 STMN4_HUMAN Affects Expression [10]
Nucleotide exchange factor SIL1 (SIL1) OTDI85I5 SIL1_HUMAN Affects Expression [10]
Cysteine-rich and transmembrane domain-containing protein 1 (CYSTM1) OT1GYXDM CYTM1_HUMAN Affects Expression [10]
Oxysterol-binding protein-related protein 2 (OSBPL2) OTCK671N OSBL2_HUMAN Affects Expression [10]
Sphingosine 1-phosphate receptor 5 (S1PR5) OTQF1R0U S1PR5_HUMAN Affects Expression [10]
Translation initiation factor IF-3, mitochondrial (MTIF3) OTPQ7FPQ IF3M_HUMAN Affects Expression [10]
RING finger protein 39 (RNF39) OTUQA9JT RNF39_HUMAN Affects Expression [10]
Interferon alpha-inducible protein 27-like protein 2 (IFI27L2) OTFOHYHK I27L2_HUMAN Affects Expression [10]
Polyadenylate-binding protein 3 (PABPC3) OTTR9DPT PABP3_HUMAN Decreases Expression [21]
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) OTYEJAGZ GPT_HUMAN Affects Expression [10]
Transcription elongation factor A protein-like 2 (TCEAL2) OT2JYBZ6 TCAL2_HUMAN Affects Expression [10]
Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A) OTPMGIU4 MLP3A_HUMAN Affects Expression [10]
PR domain zinc finger protein 12 (PRDM12) OTOAUVAM PRD12_HUMAN Increases Expression [110]
Regulator of cell cycle RGCC (RGCC) OTYJMLWM RGCC_HUMAN Affects Expression [10]
Glutathione S-transferase omega-2 (GSTO2) OTVDSNLH GSTO2_HUMAN Affects Expression [10]
Occludin/ELL domain-containing protein 1 (OCEL1) OTS4R6CX OCEL1_HUMAN Affects Expression [10]
Transcription factor SOX-17 (SOX17) OT9H4WWE SOX17_HUMAN Increases Expression [194]
Histone-lysine N-methyltransferase SMYD3 (SMYD3) OT9YR20G SMYD3_HUMAN Affects Expression [10]
Tudor domain-containing protein 3 (TDRD3) OTG83E2C TDRD3_HUMAN Affects Expression [10]
Methyltransferase-like protein 17, mitochondrial (METTL17) OTGGMKXA MET17_HUMAN Affects Expression [10]
Homeobox protein NANOG (NANOG) OTUEY1FM NANOG_HUMAN Decreases Expression [10]
Protein lin-28 homolog A (LIN28A) OTJJBRCQ LN28A_HUMAN Increases Expression [195]
TBC1 domain family member 17 (TBC1D17) OT75ZWLB TBC17_HUMAN Decreases Expression [21]
Pleckstrin homology domain-containing family A member 2 (PLEKHA2) OTY2AP6T PKHA2_HUMAN Affects Expression [10]
Sp110 nuclear body protein (SP110) OTFW6WH7 SP110_HUMAN Increases Expression [16]
MAP kinase-interacting serine/threonine-protein kinase 2 (MKNK2) OTNA9G8V MKNK2_HUMAN Affects Expression [10]
Otoferlin (OTOF) OTXQMJY8 OTOF_HUMAN Affects Expression [10]
Transcription factor HES-4 (HES4) OTCGMQDT HES4_HUMAN Affects Expression [10]
Chromodomain-helicase-DNA-binding protein 8 (CHD8) OTS7A6AF CHD8_HUMAN Increases Expression [196]
Carbohydrate-responsive element-binding protein (MLXIPL) OTR9MLLW MLXPL_HUMAN Affects Expression [10]
E3 ubiquitin-protein ligase CCNB1IP1 (CCNB1IP1) OTOTVMC8 CIP1_HUMAN Affects Expression [10]
Lactosylceramide 4-alpha-galactosyltransferase (A4GALT) OTPX3UGY A4GAT_HUMAN Affects Expression [10]
Inositol-3-phosphate synthase 1 (ISYNA1) OT49ONSE INO1_HUMAN Affects Expression [10]
Acyl-coenzyme A thioesterase 13 (ACOT13) OTWRUST1 ACO13_HUMAN Affects Expression [10]
Leucine zipper transcription factor-like protein 1 (LZTFL1) OTIEIOEW LZTL1_HUMAN Decreases Expression [21]
Ras-related GTP-binding protein D (RRAGD) OTXLVWAH RRAGD_HUMAN Affects Expression [10]
Exosome complex component RRP46 (EXOSC5) OTADUQ7H EXOS5_HUMAN Affects Expression [10]
Growth/differentiation factor 3 (GDF3) OTD3KGJK GDF3_HUMAN Affects Expression [10]
Cytochrome P450 26B1 (CYP26B1) OT92XA92 CP26B_HUMAN Affects Expression [10]
Chromatin accessibility complex protein 1 (CHRAC1) OTBXN4YZ CHRC1_HUMAN Affects Expression [10]
Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) OTKJ44KY PRDC1_HUMAN Affects Methylation [197]
Serine/threonine-protein kinase LATS2 (LATS2) OT6XO8JP LATS2_HUMAN Affects Methylation [73]
Single-pass membrane and coiled-coil domain-containing protein 4 (SMCO4) OTDLEXH4 SMCO4_HUMAN Affects Expression [10]
Dual specificity protein phosphatase 22 (DUSP22) OTEZ3U85 DUS22_HUMAN Affects Expression [10]
14 kDa phosphohistidine phosphatase (PHPT1) OTFYWNFX PHP14_HUMAN Affects Expression [10]
Sperm protein associated with the nucleus on the X chromosome A (SPANXA1) OTMK3QIS SPNXA_HUMAN Increases Expression [16]
Asc-type amino acid transporter 1 (SLC7A10) OTN1S03Q AAA1_HUMAN Affects Expression [10]
LanC-like protein 2 (LANCL2) OT7KWGMR LANC2_HUMAN Affects Expression [10]
Solute carrier family 22 member 11 (SLC22A11) OTAJLNJZ S22AB_HUMAN Increases Expression [68]
Sal-like protein 1 (SALL1) OTYYZGLH SALL1_HUMAN Increases Expression [110]
PAK4-inhibitor INKA2 (INKA2) OT9RA64U INKA2_HUMAN Affects Expression [10]
Protein DEPP1 (DEPP1) OTB36PHJ DEPP1_HUMAN Affects Expression [10]
Obg-like ATPase 1 (OLA1) OTAPOTTG OLA1_HUMAN Decreases Expression [21]
SERTA domain-containing protein 4 (SERTAD4) OTZ1GUD9 SRTD4_HUMAN Affects Expression [10]
Muscleblind-like protein 3 (MBNL3) OT2T2YOK MBNL3_HUMAN Affects Expression [10]
Shiftless antiviral inhibitor of ribosomal frameshifting protein (SHFL) OTZ4771K SHFL_HUMAN Affects Expression [10]
Probable ATP-dependent RNA helicase DDX28 (DDX28) OTIIHNYN DDX28_HUMAN Affects Expression [10]
NEDD4 family-interacting protein 2 (NDFIP2) OT34DCAP NFIP2_HUMAN Affects Expression [10]
Androgen-induced gene 1 protein (AIG1) OTJB2UTH AIG1_HUMAN Affects Expression [10]
DNA-directed RNA polymerase III subunit RPC2 (POLR3B) OT3FS9MB RPC2_HUMAN Affects Expression [10]
Host cell factor C1 regulator 1 (HCFC1R1) OTGDPS5C HPIP_HUMAN Affects Expression [10]
Nicotinamide riboside kinase 1 (NMRK1) OT0STQLV NRK1_HUMAN Affects Expression [10]
Gem-associated protein 8 (GEMIN8) OTXGA3N9 GEMI8_HUMAN Affects Expression [10]
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 (SOHLH2) OTB9EM6C SOLH2_HUMAN Increases Expression [16]
MICOS complex subunit MIC19 (CHCHD3) OT8BDECJ MIC19_HUMAN Affects Expression [10]
Probable ATP-dependent RNA helicase DDX43 (DDX43) OTK1RYSK DDX43_HUMAN Affects Expression [23]
Delta-like protein 3 (DLL3) OTLXE1TX DLL3_HUMAN Affects Expression [10]
Ras-like protein family member 12 (RASL12) OTNAK9X4 RASLC_HUMAN Affects Expression [10]
Serine/threonine-protein kinase PLK2 (PLK2) OTKMJXJ8 PLK2_HUMAN Increases Expression [10]
Proline-rich protein 13 (PRR13) OTXPP37T PRR13_HUMAN Affects Expression [10]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (SMARCAL1) OTTKXLUZ SMAL1_HUMAN Affects Expression [10]
G-protein coupled receptor family C group 5 member B (GPRC5B) OTF3S5E3 GPC5B_HUMAN Affects Expression [23]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1) OTY6ZHVA RGL1_HUMAN Affects Expression [10]
Aryl-hydrocarbon-interacting protein-like 1 (AIPL1) OT4VBD78 AIPL1_HUMAN Affects Expression [10]
DnaJ homolog subfamily C member 27 (DNAJC27) OTJRPCUR DJC27_HUMAN Affects Expression [10]
Potassium voltage-gated channel subfamily D member 2 (KCND2) OTIFUVV7 KCND2_HUMAN Affects Expression [10]
Dentin sialophosphoprotein (DSPP) OT1TYNDN DSPP_HUMAN Increases Expression [16]
Protein PALS2 (PALS2) OTV12NKE PALS2_HUMAN Affects Expression [10]
Coiled-coil domain-containing protein 167 (CCDC167) OTUIAUE7 CC167_HUMAN Affects Expression [10]
Spermatogenesis-associated protein 7 (SPATA7) OT78G2IH SPAT7_HUMAN Affects Expression [10]
Signal-induced proliferation-associated 1-like protein 2 (SIPA1L2) OT8NJE5D SI1L2_HUMAN Affects Expression [10]
Protein NYNRIN (NYNRIN) OTZ296OC NYNRI_HUMAN Affects Expression [10]
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (B3GAT1) OTXFP98E B3GA1_HUMAN Affects Expression [10]
Methyl-CpG-binding domain protein 2 (MBD2) OTUQPP0R MBD2_HUMAN Decreases Activity [157]
COMM domain-containing protein 3 (COMMD3) OT1UTJH4 COMD3_HUMAN Affects Expression [10]
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C) OTQ2R629 MGT4C_HUMAN Affects Expression [10]
Dickkopf-related protein 3 (DKK3) OTDU94EY DKK3_HUMAN Affects Expression [10]
Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) OTU4J3ZI HEY2_HUMAN Affects Expression [10]
Cathepsin Z (CTSZ) OTSCX2LL CATZ_HUMAN Affects Expression [66]
E3 ubiquitin-protein ligase RNF14 (RNF14) OTWX0D0H RNF14_HUMAN Affects Expression [10]
Dickkopf-related protein 2 (DKK2) OTKSZSUM DKK2_HUMAN Increases Expression [110]
Peflin (PEF1) OTY24CUW PEF1_HUMAN Affects Expression [10]
Homeobox expressed in ES cells 1 (HESX1) OT5E2Z4G HESX1_HUMAN Affects Expression [10]
Tight junction protein ZO-2 (TJP2) OTQUY6BV ZO2_HUMAN Affects Expression [10]
Craniofacial development protein 1 (CFDP1) OTXY7J96 CFDP1_HUMAN Affects Expression [10]
Pleckstrin homology domain-containing family B member 1 (PLEKHB1) OTC7TNAX PKHB1_HUMAN Affects Expression [10]
Neuronal-specific septin-3 (SEPTIN3) OTOZ6PIM SEPT3_HUMAN Affects Expression [10]
SUN domain-containing protein 2 (SUN2) OT2IQJUC SUN2_HUMAN Decreases Expression [21]
DNA mismatch repair protein Mlh3 (MLH3) OT91PPBI MLH3_HUMAN Increases Expression [18]
Tachykinin-3 (TAC3) OTOJGM38 TKNK_HUMAN Affects Expression [10]
Epidermal growth factor-like protein 7 (EGFL7) OTUH6J9L EGFL7_HUMAN Increases Expression [198]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) OTTLJH8W ATS1_HUMAN Increases Expression [199]
ATP-dependent RNA helicase DDX25 (DDX25) OTF36NBP DDX25_HUMAN Affects Expression [10]
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAIAP2L1) OTZ71SK9 BI2L1_HUMAN Affects Expression [10]
SERTA domain-containing protein 1 (SERTAD1) OTBHKZQP SRTD1_HUMAN Affects Expression [10]
Rap guanine nucleotide exchange factor-like 1 (RAPGEFL1) OTYKE9ZM RPGFL_HUMAN Decreases Expression [21]
Transgelin-3 (TAGLN3) OTJBP3VJ TAGL3_HUMAN Affects Expression [10]
ATPase inhibitor, mitochondrial (ATP5IF1) OTQFD73H ATIF1_HUMAN Affects Expression [10]
E3 ISG15--protein ligase HERC5 (HERC5) OTZ5PR39 HERC5_HUMAN Affects Expression [10]
Death-associated protein kinase 2 (DAPK2) OTWODUQG DAPK2_HUMAN Increases Expression [59]
Methyl-CpG-binding domain protein 1 (MBD1) OTD19VO6 MBD1_HUMAN Increases Expression [135]
Mitochondrial peptide methionine sulfoxide reductase (MSRA) OTBS15SD MSRA_HUMAN Affects Expression [10]
Regulating synaptic membrane exocytosis protein 3 (RIMS3) OTHN3H0A RIMS3_HUMAN Affects Expression [10]
ERBB receptor feedback inhibitor 1 (ERRFI1) OT7VZ2IZ ERRFI_HUMAN Increases Expression [58]
Lymphoid enhancer-binding factor 1 (LEF1) OTWS5I5H LEF1_HUMAN Decreases Expression [118]
Heat shock protein beta-8 (HSPB8) OT0I83YS HSPB8_HUMAN Affects Expression [10]
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) OTR0B67G NAGPA_HUMAN Affects Expression [10]
Inhibitor of growth protein 1 (ING1) OTEZBRKW ING1_HUMAN Affects Expression [10]
Zinc finger protein Aiolos (IKZF3) OTOX5H49 IKZF3_HUMAN Affects Methylation [200]
Phospholipase A and acyltransferase 4 (PLAAT4) OTI66SAJ PLAT4_HUMAN Affects Expression [10]
Paraneoplastic antigen Ma2 (PNMA2) OTF5YBQG PNMA2_HUMAN Affects Expression [10]
Ras-related protein Rab-23 (RAB23) OTBAKFBR RAB23_HUMAN Affects Expression [10]
Protein NDRG4 (NDRG4) OTJBOTD8 NDRG4_HUMAN Affects Expression [10]
Protein phosphatase 1H (PPM1H) OTKSVU7S PPM1H_HUMAN Affects Expression [23]
TP53-target gene 3 protein (TP53TG3) OTWS7OY4 T53G3_HUMAN Affects Expression [10]
Collagen alpha-1(XVII) chain (COL17A1) OTID5AH2 COHA1_HUMAN Increases Expression [16]
Calpain-11 (CAPN11) OTEHK57V CAN11_HUMAN Affects Expression [10]
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) OTC2R00C PACN2_HUMAN Affects Expression [10]
Endothelial protein C receptor (PROCR) OTRHED17 EPCR_HUMAN Affects Expression [10]
A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAMTS8) OT2KFY1S ATS8_HUMAN Affects Expression [10]
Protein bassoon (BSN) OTZ72VIB BSN_HUMAN Decreases Expression [21]
Probable G-protein coupled receptor 34 (GPR34) OT61HEHW GPR34_HUMAN Affects Expression [23]
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1) OTVX8835 AGAP1_HUMAN Affects Expression [10]
Sodium/calcium exchanger 2 (SLC8A2) OT590PIZ NAC2_HUMAN Affects Expression [10]
Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) OTUN9GUS NOD1_HUMAN Affects Expression [10]
Leucine zipper putative tumor suppressor 1 (LZTS1) OTXXL864 LZTS1_HUMAN Affects Expression [10]
Heparanase (HPSE) OTPTK5VS HPSE_HUMAN Affects Expression [201]
RuvB-like 1 (RUVBL1) OTWV19L7 RUVB1_HUMAN Affects Expression [23]
Heparan sulfate glucosamine 3-O-sulfotransferase 2 (HS3ST2) OTWFA0GJ HS3S2_HUMAN Increases Expression [110]
cAMP-dependent protein kinase inhibitor gamma (PKIG) OTOIWE5G IPKG_HUMAN Affects Expression [10]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5) OT03QCLM ATF5_HUMAN Affects Expression [10]
Epididymis-specific alpha-mannosidase (MAN2B2) OTU9V3PE MA2B2_HUMAN Affects Expression [10]
Protein EFR3 homolog B (EFR3B) OTVKWU2L EFR3B_HUMAN Affects Expression [10]
Band 4.1-like protein 3 (EPB41L3) OTS6CHG2 E41L3_HUMAN Affects Expression [190]
Ragulator complex protein LAMTOR2 (LAMTOR2) OTHEDISB LTOR2_HUMAN Affects Expression [10]
Polymerase delta-interacting protein 2 (POLDIP2) OT8SZSJ6 PDIP2_HUMAN Affects Expression [10]
Transmembrane emp24 domain-containing protein 3 (TMED3) OTNOPHHC TMED3_HUMAN Affects Expression [10]
Lysyl oxidase homolog 2 (LOXL2) OTRT46B5 LOXL2_HUMAN Increases Expression [202]
Sorting and assembly machinery component 50 homolog (SAMM50) OTRYFYIU SAM50_HUMAN Affects Expression [10]
Leucine-rich repeat-containing protein 42 (LRRC42) OTZ02075 LRC42_HUMAN Affects Expression [10]
Intraflagellar transport protein 25 homolog (IFT25) OTDR1HG6 IFT25_HUMAN Affects Expression [10]
NEDD8 ultimate buster 1 (NUB1) OTWA6RTX NUB1_HUMAN Affects Expression [10]
DnaJ homolog subfamily C member 15 (DNAJC15) OTNDUKAA DJC15_HUMAN Affects Expression [23]
Krueppel-like factor 2 (KLF2) OTIP1UFX KLF2_HUMAN Affects Expression [10]
Glypican-6 (GPC6) OTNJBESF GPC6_HUMAN Affects Expression [10]
Transcription factor SOX-21 (SOX21) OTNT50CC SOX21_HUMAN Affects Expression [10]
Adhesion G-protein coupled receptor G1 (ADGRG1) OTQBB8NT AGRG1_HUMAN Affects Expression [10]
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (SIRT4) OT5S0J23 SIR4_HUMAN Affects Expression [10]
Proton-coupled zinc antiporter SLC30A1 (SLC30A1) OTY8J0S4 ZNT1_HUMAN Affects Expression [10]
Roundabout homolog 1 (ROBO1) OT52UFVS ROBO1_HUMAN Affects Methylation [65]
Sestrin-1 (SESN1) OTSFDZWL SESN1_HUMAN Affects Expression [10]
Dual specificity protein phosphatase 10 (DUSP10) OTNG467B DUS10_HUMAN Affects Expression [10]
Calmodulin-binding transcription activator 1 (CAMTA1) OTAN1S5B CMTA1_HUMAN Affects Expression [10]
Liver carboxylesterase 1 (CES1) OT9L0LR8 EST1_HUMAN Increases Abundance [203]
Histone-lysine N-methyltransferase EHMT2 (EHMT2) OTC4DWB6 EHMT2_HUMAN Affects Response To Substance [24]
Sodium/nucleoside cotransporter 1 (SLC28A1) OTXWVV9O S28A1_HUMAN Increases Response To Substance [204]
DNA (DNMT3B) OTZ0JCNP DNM3B_HUMAN Decreases Response To Substance [10]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Decreases Response To Substance [76]
------------------------------------------------------------------------------------
⏷ Show the Full List of 1481 DOT(s)
Indication(s) of Tetrahydrouridine
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2 [4]
Tetrahydrouridine Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Cytidine deaminase (CDA) TTQ12RK CDD_HUMAN Modulator [205]
------------------------------------------------------------------------------------
Tetrahydrouridine Interacts with 1 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Cytidine deaminase (CDA) OT3HXP6N CDD_HUMAN Decreases Activity [206]
------------------------------------------------------------------------------------

Test Results of This Drug Combination in Other Disease Systems

Indication DrugCom ID Cell Line Status REF
Neoplasm Metastasis DCVQGIG N. A. Phase 1 [207]
------------------------------------------------------------------------------------

References

1 ClinicalTrials.gov (NCT02847000) p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Pancreatic Cancer
2 Decitabine FDA Label
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6805).
4 Quantitative determination of the cytidine deaminase inhibitor tetrahydrouridine (THU) in mouse plasma by liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom. 2007;21(13):1991-7.
5 Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. Cancer Sci. 2006 Jan;97(1):64-71.
6 Aberrant promoter methylation of the ABCG2 gene in renal carcinoma. Mol Cell Biol. 2006 Nov;26(22):8572-85.
7 Gene induction and apoptosis in human hepatocellular carci-noma cells SMMC-7721 exposed to 5-aza-2'-deoxycytidine. Chin Med J (Engl). 2007 Sep 20;120(18):1626-31.
8 The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. Leukemia. 2009 Jun;23(6):1019-28.
9 Epigenetic regulation is a crucial factor in the repression of UGT1A1 expression in the human kidney. Drug Metab Dispos. 2013 Oct;41(10):1738-43.
10 Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation. PLoS One. 2012;7(12):e53003. doi: 10.1371/journal.pone.0053003. Epub 2012 Dec 27.
11 Transcriptional activity of the novel identified human yy2 promoter is modified by DNA methylation. Gene. 2009 Feb 1;430(1-2):58-63. doi: 10.1016/j.gene.2008.10.013. Epub 2008 Nov 5.
12 Epigenetic silencing of SFRP5 promotes the metastasis and invasion of chondrosarcoma by expression inhibition and Wnt signaling pathway activation. Chem Biol Interact. 2018 Dec 25;296:1-8. doi: 10.1016/j.cbi.2018.08.020. Epub 2018 Aug 18.
13 Ornithine decarboxylase antizyme upregulates DNA-dependent protein kinase and enhances the nonhomologous end-joining repair of DNA double-strand breaks in human oral cancer cells. Biochemistry. 2007 Aug 7;46(31):8920-32. doi: 10.1021/bi7000328. Epub 2007 Jul 14.
14 [Effect of arsenic trioxide and 5-aza-2'-deoxycytidine on SHP-1, JAK3, TYK2 gene expression in K562 cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2014 Apr;22(2):323-8. doi: 10.7534/j.issn.1009-2137.2014.02.011.
15 Methylation-mediated loss of SFRP2 enhances invasiveness of non-small cell lung cancer cells. Hum Exp Toxicol. 2018 Feb;37(2):155-162. doi: 10.1177/0960327117693071. Epub 2017 Feb 21.
16 Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer. Mol Oncol. 2011 Oct;5(5):438-53. doi: 10.1016/j.molonc.2011.07.003. Epub 2011 Jul 26.
17 5-Aza-2'-deoxycytidine sensitizes busulfan-resistant myeloid leukemia cells by regulating expression of genes involved in cell cycle checkpoint and apoptosis. Leuk Res. 2010 Mar;34(3):364-72. doi: 10.1016/j.leukres.2009.08.014. Epub 2009 Sep 3.
18 DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells. Cancer Lett. 2012 Mar;316(1):62-9. doi: 10.1016/j.canlet.2011.10.022. Epub 2011 Oct 23.
19 Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells. Int J Oncol. 2008 Jun;32(6):1227-35. doi: 10.3892/ijo_32_6_1227.
20 [Frequent epigenetic inactivation of XAF1 by promotor hypermethylation in human colon cancers]. Korean J Gastroenterol. 2005 Apr;45(4):285-93.
21 DNA methylation inhibits p53-mediated survivin repression. Oncogene. 2009 May 14;28(19):2046-50. doi: 10.1038/onc.2009.62. Epub 2009 Apr 13.
22 Zinc finger protein 671 has a cancer-inhibiting function in colorectal carcinoma via the deactivation of Notch signaling. Toxicol Appl Pharmacol. 2023 Jan 1;458:116326. doi: 10.1016/j.taap.2022.116326. Epub 2022 Nov 24.
23 Epigenetic silencing of novel tumor suppressors in malignant melanoma. Cancer Res. 2006 Dec 1;66(23):11187-93. doi: 10.1158/0008-5472.CAN-06-1274.
24 Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells. Mol Cancer Res. 2009 Jun;7(6):851-62. doi: 10.1158/1541-7786.MCR-08-0497. Epub 2009 Jun 16.
25 Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression. Clin Cancer Res. 2007 Jan 1;13(1):268-74. doi: 10.1158/1078-0432.CCR-06-2038.
26 2006 drug approvals: finding the niche. Nat Rev Drug Discov. 2007 Feb;6(2):99-101.
27 Tracking decitabine incorporation into malignant myeloid cell DNA in vitro and in vivo by LC-MS/MS with enzymatic digestion. Sci Rep. 2019 Mar 14;9(1):4558.
28 Mycoplasma hyorhinis-encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs. FEBS Open Bio. 2015 Aug 3;5:634-9.
29 Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. Cancer Res. 2007 Jul 1;67(13):6400-8. doi: 10.1158/0008-5472.CAN-07-0251.
30 Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention. Ann Rheum Dis. 2007 Dec;66(12):1616-21. doi: 10.1136/ard.2007.069377. Epub 2007 May 14.
31 Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. J Clin Endocrinol Metab. 2008 Sep;93(9):3610-7. doi: 10.1210/jc.2008-0578. Epub 2008 Jun 10.
32 Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells. J Biol Chem. 2001 Oct 26;276(43):39990-40000.
33 Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. J Clin Invest. 2004 Oct;114(8):1146-57.
34 Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells. Hum Pathol. 2006 Mar;37(3):298-311.
35 Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression. Biochem Cell Biol. 2007 Jun;85(3):337-46.
36 A role for DNA methylation in regulating the growth suppressor PMEPA1 gene in prostate cancer. Epigenetics. 2007 Apr-Jun;2(2):100-9.
37 Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells. Carcinogenesis. 2008 Nov;29(11):2175-81.
38 The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet. 2009 Feb;41(2):178-186.
39 Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers. Pharmacogenomics J. 2009 Jun;9(3):208-17.
40 The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells. Toxicol Lett. 2010 Feb 1;192(2):119-25.
41 Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes. Mol Pharmacol. 2010 Oct;78(4):608-16.
42 Epigenetic influences of low-dose bisphenol A in primary human breast epithelial cells. Toxicol Appl Pharmacol. 2010 Oct 15;248(2):111-21.
43 Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells. Toxicology. 2011 Jul 29;285(3):97-103.
44 Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis. Toxicol Appl Pharmacol. 2014 Sep 15;279(3):322-330.
45 Aryl hydrocarbon receptor ligand 5F 203 induces oxidative stress that triggers DNA damage in human breast cancer cells. Chem Res Toxicol. 2015 May 18;28(5):855-71.
46 Differential DNA methylation profile of key genes in malignant prostate epithelial cells transformed by inorganic arsenic or cadmium. Toxicol Appl Pharmacol. 2015 Aug 1;286(3):159-67.
47 Antineoplastic effects of decitabine, an inhibitor of DNA promoter methylation, in adrenocortical carcinoma cells. Arch Surg. 2010 Mar;145(3):226-32. doi: 10.1001/archsurg.2009.292.
48 Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL. Oncogene. 2008 Jan 17;27(4):490-8. doi: 10.1038/sj.onc.1210655. Epub 2007 Jul 23.
49 Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. Proteomics. 2009 Apr;9(7):1952-66. doi: 10.1002/pmic.200701089.
50 Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours. Br J Cancer. 2007 Nov 19;97(10):1416-24. doi: 10.1038/sj.bjc.6604032. Epub 2007 Oct 16.
51 Methylation silencing of the Apaf-1 gene in acute leukemia. Mol Cancer Res. 2005 Jun;3(6):325-34. doi: 10.1158/1541-7786.MCR-04-0105.
52 Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma. Brain Res. 2008 Jan 10;1188:173-81. doi: 10.1016/j.brainres.2007.10.043. Epub 2007 Oct 26.
53 DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. Mol Cell Biol. 2008 Jan;28(2):752-71. doi: 10.1128/MCB.01799-07. Epub 2007 Nov 8.
54 Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas. Clin Cancer Res. 2009 Jun 1;15(11):3881-8. doi: 10.1158/1078-0432.CCR-08-2196. Epub 2009 May 26.
55 Treatment of chronic lymphocytic leukemia with a hypomethylating agent induces expression of NXF2, an immunogenic cancer testis antigen. Clin Cancer Res. 2009 May 15;15(10):3406-15. doi: 10.1158/1078-0432.CCR-08-2099. Epub 2009 Apr 28.
56 Downmodulation of dimethyl transferase activity enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in prostate cancer cells. Int J Oncol. 2008 Aug;33(2):381-8.
57 DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells. J Cancer Res Clin Oncol. 2009 Dec;135(12):1791-8. doi: 10.1007/s00432-009-0627-z. Epub 2009 Jun 24.
58 Decitabine up-regulates S100A2 expression and synergizes with IFN-gamma to kill uveal melanoma cells. Clin Cancer Res. 2007 Sep 1;13(17):5219-25. doi: 10.1158/1078-0432.CCR-07-0816.
59 DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells. Cancer Sci. 2009 Jan;100(1):181-8. doi: 10.1111/j.1349-7006.2008.01004.x. Epub 2008 Nov 25.
60 Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia. Eur J Cancer. 2009 Jul;45(10):1877-89. doi: 10.1016/j.ejca.2009.04.005. Epub 2009 May 4.
61 Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes. Oncogene. 2008 Jan 10;27(3):378-86. doi: 10.1038/sj.onc.1210648. Epub 2007 Jul 9.
62 Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas. Haematologica. 2007 Apr;92(4):460-8. doi: 10.3324/haematol.10337.
63 CpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 binding. Nucleic Acids Res. 2008 Jan;36(1):330-41. doi: 10.1093/nar/gkm1028. Epub 2007 Nov 22.
64 Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. Blood. 2008 Feb 15;111(4):2382-4. doi: 10.1182/blood-2007-07-103960. Epub 2007 Nov 30.
65 Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation. Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4336-44. doi: 10.1158/1078-0432.CCR-07-0015.
66 A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. PLoS Med. 2006 Dec;3(12):e486. doi: 10.1371/journal.pmed.0030486.
67 Transporter gene expression in human head and neck squamous cell carcinoma and associated epigenetic regulatory mechanisms. Am J Pathol. 2013 Jan;182(1):234-43. doi: 10.1016/j.ajpath.2012.09.008. Epub 2012 Nov 6.
68 Multiple drug transporters mediate the placental transport of sulpiride. Arch Toxicol. 2017 Dec;91(12):3873-3884. doi: 10.1007/s00204-017-2008-8. Epub 2017 Jun 9.
69 Epigenetic inactivation of SLIT2 in human hepatocellular carcinomas. Biochem Biophys Res Commun. 2009 Jan 30;379(1):86-91. doi: 10.1016/j.bbrc.2008.12.022. Epub 2008 Dec 17.
70 SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer. Oncogene. 2015 Aug 13;34(33):4391-402. doi: 10.1038/onc.2014.370. Epub 2014 Dec 1.
71 Relation of DNA methylation of 5'-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma. PLoS One. 2009;4(2):e4488. doi: 10.1371/journal.pone.0004488. Epub 2009 Feb 16.
72 Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis. Oncogene. 2010 Sep 16;29(37):5159-70. doi: 10.1038/onc.2010.255. Epub 2010 Jun 21.
73 Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma. Neurosci Res. 2006 Dec;56(4):450-8. doi: 10.1016/j.neures.2006.09.006. Epub 2006 Oct 17.
74 Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer. Cancer Sci. 2007 Feb;98(2):169-73. doi: 10.1111/j.1349-7006.2006.00367.x.
75 Changes in gene expression and assessment of DNA methylation in primary human hepatocytes and HepG2 cells exposed to the environmental contaminants-Hexabromocyclododecane and 17-beta oestradiol. Toxicology. 2009 Feb 27;256(3):143-51. doi: 10.1016/j.tox.2008.10.017. Epub 2008 Nov 5.
76 Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. PLoS One. 2009;4(2):e4563. doi: 10.1371/journal.pone.0004563. Epub 2009 Feb 23.
77 Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2'-deoxycytidine in cutaneous melanoma: immunotherapeutic implications. Clin Cancer Res. 2007 Jun 1;13(11):3333-8. doi: 10.1158/1078-0432.CCR-06-3091.
78 CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer. Int J Oncol. 2009 Jun;34(6):1593-602. doi: 10.3892/ijo_00000289.
79 Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. Breast Cancer Res Treat. 2008 Sep;111(1):15-25. doi: 10.1007/s10549-007-9751-0. Epub 2007 Sep 21.
80 Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines. Biomed Pharmacother. 2007 Aug;61(7):451-4. doi: 10.1016/j.biopha.2007.03.007. Epub 2007 Apr 20.
81 Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells. Epigenetics. 2006 Oct-Dec;1(4):163-71. doi: 10.4161/epi.1.4.3401. Epub 2006 Sep 13.
82 Semenogelin I expression in myeloma cells can be upregulated pharmacologically. Leuk Res. 2008 Dec;32(12):1889-94. doi: 10.1016/j.leukres.2008.03.036. Epub 2008 May 12.
83 TP53 promoter methylation in human gliomas. Acta Neuropathol. 2005 Aug;110(2):178-84. doi: 10.1007/s00401-005-1041-5. Epub 2005 Jul 16.
84 [Analysis of in vitro anti-leukemia effect of 5-aza-2'-deoxycitydine]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2008 Apr;33(4):344-52.
85 Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells. Mol Cancer Ther. 2007 Nov;6(11):3071-9. doi: 10.1158/1535-7163.MCT-07-0117.
86 SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas. Oncogene. 2007 Aug 16;26(38):5662-8. doi: 10.1038/sj.onc.1210338. Epub 2007 Mar 5.
87 Activator protein 2alpha status determines the chemosensitivity of cancer cells: implications in cancer chemotherapy. Cancer Res. 2005 Oct 1;65(19):8628-34. doi: 10.1158/0008-5472.CAN-05-1059.
88 Growth inhibition of human cancer cells by 5-aza-2'-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status. Mol Cancer Ther. 2009 Apr;8(4):779-85. doi: 10.1158/1535-7163.MCT-08-0926.
89 A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons. CNS Neurosci Ther. 2013 Mar;19(3):183-90. doi: 10.1111/cns.12059.
90 Silencing of the CKII alpha and CKII alpha' genes during cellular senescence is mediated by DNA methylation. Gene. 2009 Feb 15;431(1-2):55-60. doi: 10.1016/j.gene.2008.10.020. Epub 2008 Nov 6.
91 Transient resistance to DNA damaging agents is associated with expression of microRNAs-135b and -196b in human leukemia cell lines. Int J Biochem Mol Biol. 2016 Aug 5;7(2):27-47. eCollection 2016.
92 Aberrant DNA methylation of the Src kinase Hck, but not of Lyn, in Philadelphia chromosome negative acute lymphocytic leukemia. Leukemia. 2007 May;21(5):906-11. doi: 10.1038/sj.leu.2404615. Epub 2007 Mar 8.
93 Epigenetic regulation of c-ROS receptor tyrosine kinase expression in malignant gliomas. Cancer Res. 2009 Mar 15;69(6):2180-4. doi: 10.1158/0008-5472.CAN-08-3351. Epub 2009 Mar 10.
94 A repressive epigenetic domino effect confers susceptibility to breast epithelial cell transformation: implications for predicting breast cancer risk. Cancer Res. 2006 Nov 1;66(21):10308-14. doi: 10.1158/0008-5472.CAN-06-1052.
95 Promoter hypermethylation mediated downregulation of FBP1 in human hepatocellular carcinoma and colon cancer. PLoS One. 2011;6(10):e25564. doi: 10.1371/journal.pone.0025564. Epub 2011 Oct 19.
96 Frequent inactivation of SPARC by promoter hypermethylation in colon cancers. Int J Cancer. 2007 Aug 1;121(3):567-75. doi: 10.1002/ijc.22706.
97 Induction of intestinalization in human esophageal keratinocytes is a multistep process. Carcinogenesis. 2009 Jan;30(1):122-30. doi: 10.1093/carcin/bgn227. Epub 2008 Oct 8.
98 Epigenetic mediated transcriptional activation of PARP-1 participates in silica-associated malignant transformation of human bronchial epithelial cells. Toxicol Lett. 2010 Apr 1;193(3):236-41. doi: 10.1016/j.toxlet.2010.01.017. Epub 2010 Feb 1.
99 An epigenetic disorder may cause aberrant expression of aromatase gene in endometriotic stromal cells. Fertil Steril. 2008 May;89(5 Suppl):1390-6. doi: 10.1016/j.fertnstert.2007.03.078. Epub 2007 Jul 26.
100 Differential expression of secretory phospholipases A2 in normal and malignant prostate cell lines: regulation by cytokines, cell signaling pathways, and epigenetic mechanisms. Neoplasia. 2008 Mar;10(3):279-86. doi: 10.1593/neo.07965.
101 Cell cycle regulation of human endometrial stromal cells during decidualization. Reprod Sci. 2012 Aug;19(8):883-94. doi: 10.1177/1933719112438447. Epub 2012 Apr 24.
102 Epigenetic regulation of human trophoblastic cell migration and invasion. Endocrinology. 2006 Nov;147(11):5275-83. doi: 10.1210/en.2006-0288. Epub 2006 Aug 3.
103 Methylation status of the Ep-CAM promoter region in human breast cancer cell lines and breast cancer tissue. Cancer Lett. 2007 Feb 8;246(1-2):253-61. doi: 10.1016/j.canlet.2006.03.002. Epub 2006 Apr 18.
104 Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins. Mol Cancer Ther. 2005 Jan;4(1):61-9.
105 Down-regulation of IL-7Ralpha expression in human T cells via DNA methylation. J Immunol. 2007 May 1;178(9):5473-9. doi: 10.4049/jimmunol.178.9.5473.
106 Angiostatic activity of DNA methyltransferase inhibitors. Mol Cancer Ther. 2006 Feb;5(2):467-75. doi: 10.1158/1535-7163.MCT-05-0417.
107 Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation. Oral Oncol. 2007 Oct;43(9):898-904. doi: 10.1016/j.oraloncology.2006.11.004. Epub 2007 Feb 15.
108 Modulation of HLA-G expression. Neoplasma. 2007;54(6):455-62.
109 Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth. Cancer Res. 2007 Jun 1;67(11):5328-36. doi: 10.1158/0008-5472.CAN-06-4265.
110 Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study. Oncotarget. 2017 Jan 3;8(1):1369-1391. doi: 10.18632/oncotarget.13622.
111 Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells. Cancer Res. 2009 Jan 1;69(1):55-64. doi: 10.1158/0008-5472.CAN-08-0245.
112 Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy. Mol Cancer Res. 2009 Feb;7(2):199-209. doi: 10.1158/1541-7786.MCR-08-0314. Epub 2009 Feb 10.
113 Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation. Cancer Lett. 2006 Oct 28;242(2):191-7. doi: 10.1016/j.canlet.2005.11.009. Epub 2006 Jan 19.
114 Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation. Carcinogenesis. 2009 Feb;30(2):348-55. doi: 10.1093/carcin/bgn266. Epub 2008 Nov 26.
115 Regulation of opioid and cannabinoid receptor genes in human neuroblastoma and T cells by the epigenetic modifiers trichostatin A and 5-aza-2'-deoxycytidine. Neuroimmunomodulation. 2012;19(3):180-6. doi: 10.1159/000331474. Epub 2012 Jan 18.
116 Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival. Br J Cancer. 2009 Apr 7;100(7):1095-102. doi: 10.1038/sj.bjc.6604970. Epub 2009 Mar 10.
117 Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer. World J Gastroenterol. 2007 Nov 21;13(43):5692-8. doi: 10.3748/wjg.v13.i43.5692.
118 Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. Leukemia. 2009 Sep;23(9):1658-66. doi: 10.1038/leu.2009.86. Epub 2009 Apr 23.
119 Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target. Cancer Res. 2009 Feb 15;69(4):1527-35. doi: 10.1158/0008-5472.CAN-08-3609. Epub 2009 Feb 3.
120 Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. FASEB J. 2007 Jul;21(9):1979-93. doi: 10.1096/fj.06-7118com. Epub 2007 Mar 23.
121 Absence of Metallothionein 3 Expression in Breast Cancer is a Rare, But Favorable Marker of Outcome that is Under Epigenetic Control. Toxicol Environ Chem. 2010 Oct;92(9):1673-1695. doi: 10.1080/02772241003711274.
122 Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis. Cell Death Differ. 2007 Feb;14(2):275-85. doi: 10.1038/sj.cdd.4401979. Epub 2006 Jun 9.
123 Down-regulation of Rap1GAP via promoter hypermethylation promotes melanoma cell proliferation, survival, and migration. Cancer Res. 2009 Jan 15;69(2):449-57. doi: 10.1158/0008-5472.CAN-08-2399.
124 Expression of glutathione S-transferase M2 in stage I/II non-small cell lung cancer and alleviation of DNA damage exposure to benzo[a]pyrene. Toxicol Lett. 2010 Feb 15;192(3):316-23. doi: 10.1016/j.toxlet.2009.11.003. Epub 2009 Nov 10.
125 [SHP-1 gene's methylation status of Daudi lymphoma cell and the demethylation effect of 5-aza-2'-deoxycytidine]. Zhonghua Xue Ye Xue Za Zhi. 2006 Oct;27(10):670-4.
126 Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays. PLoS One. 2009;4(3):e4830. doi: 10.1371/journal.pone.0004830. Epub 2009 Mar 13.
127 Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. Cancer Res. 2007 Feb 1;67(3):1203-11. doi: 10.1158/0008-5472.CAN-06-2310.
128 Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma. Br J Cancer. 2007 Jul 16;97(2):267-74. doi: 10.1038/sj.bjc.6603852. Epub 2007 Jun 19.
129 Effects of 5-Aza-CdR on cell proliferation of breast cancer cell line MDA-MB-435S and expression of maspin gene. J Huazhong Univ Sci Technolog Med Sci. 2007 Oct;27(5):543-6. doi: 10.1007/s11596-007-0517-z.
130 Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer. Chem Biol Interact. 2016 Oct 25;258:21-9. doi: 10.1016/j.cbi.2016.08.010. Epub 2016 Aug 16.
131 Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs. Clin Cancer Res. 2009 Mar 1;15(5):1519-26. doi: 10.1158/1078-0432.CCR-08-1778. Epub 2009 Feb 17.
132 Expression and promoter methylation status of mismatch repair gene hMLH1 and hMSH2 in epithelial ovarian cancer. Aust N Z J Obstet Gynaecol. 2008 Oct;48(5):505-9. doi: 10.1111/j.1479-828X.2008.00892.x.
133 Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway. Leuk Res. 2003 Nov;27(11):999-1007. doi: 10.1016/s0145-2126(03)00068-7.
134 [Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2007 Jan;38(1):57-9.
135 Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. Carcinogenesis. 2009 Jun;30(6):1041-8. doi: 10.1093/carcin/bgp073. Epub 2009 Mar 27.
136 Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition. Br J Haematol. 2007 Sep;138(5):616-23. doi: 10.1111/j.1365-2141.2007.06707.x.
137 The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma. Int J Cancer. 2008 Jun 1;122(11):2542-53. doi: 10.1002/ijc.23407.
138 Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas. Lab Invest. 2009 Jul;89(7):791-9. doi: 10.1038/labinvest.2009.50. Epub 2009 Jun 8.
139 Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. Neoplasia. 2007 Nov;9(11):970-8. doi: 10.1593/neo.07661.
140 Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications. Biochem Biophys Res Commun. 2009 May 8;382(3):519-24. doi: 10.1016/j.bbrc.2009.03.049. Epub 2009 Mar 14.
141 Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer. Cancer Res. 2009 Jun 1;69(11):4691-9. doi: 10.1158/0008-5472.CAN-08-0142. Epub 2009 May 12.
142 Regulation of leptin receptor expression in human papillary thyroid cancer cells. Biomed Pharmacother. 2012 Sep;66(6):469-73. doi: 10.1016/j.biopha.2012.03.008. Epub 2012 Mar 31.
143 The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia. Blood. 2007 May 1;109(9):3895-905. doi: 10.1182/blood-2006-08-040147. Epub 2007 Jan 18.
144 Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. Int J Cancer. 2007 Jan 1;120(1):24-31. doi: 10.1002/ijc.22073.
145 Effect of cytarabine and decitabine in combination in human leukemic cell lines. Clin Cancer Res. 2007 Jul 15;13(14):4225-32. doi: 10.1158/1078-0432.CCR-06-2762.
146 Chromium(VI) causes down regulation of biotinidase in human bronchial epithelial cells by modifications of histone acetylation. Toxicol Lett. 2011 Aug 28;205(2):140-5. doi: 10.1016/j.toxlet.2011.05.1032. Epub 2011 May 27.
147 Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. Int J Cancer. 2007 Jan 1;120(1):32-8. doi: 10.1002/ijc.22185.
148 Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression. Biochem Biophys Res Commun. 2008 Nov 7;376(1):15-20. doi: 10.1016/j.bbrc.2008.08.015. Epub 2008 Aug 13.
149 Resistance to Fas-mediated apoptosis is restored by cycloheximide through the downregulation of cellular FLIPL in NK/T-cell lymphoma. Lab Invest. 2005 Jul;85(7):874-84. doi: 10.1038/labinvest.3700291.
150 Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers. Ann Surg Oncol. 2007 Apr;14(4):1397-404. doi: 10.1245/s10434-006-9089-6. Epub 2006 Dec 29.
151 Disturbance of the Dlk1-Dio3 imprinted domain may underlie placental Dio3 suppression and extracellular thyroid hormone disturbance in placenta-derived JEG-3 cells following decabromodiphenyl ether (BDE209) exposure. Toxicology. 2021 Jun 30;458:152837. doi: 10.1016/j.tox.2021.152837. Epub 2021 Jun 21.
152 The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas. Oncol Rep. 2008 Nov;20(5):1265-8.
153 Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2. Biochim Biophys Acta. 2007 Sep-Oct;1769(9-10):546-58. doi: 10.1016/j.bbaexp.2007.06.004. Epub 2007 Jul 6.
154 Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells. Breast Cancer Res Treat. 2011 Nov;130(1):73-83. doi: 10.1007/s10549-010-1304-2. Epub 2010 Dec 18.
155 Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis. Cancer. 2008 Jan 1;112(1):43-9. doi: 10.1002/cncr.23135.
156 Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression. J Leukoc Biol. 2006 Dec;80(6):1462-72. doi: 10.1189/jlb.0106005. Epub 2006 Sep 25.
157 BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer. Carcinogenesis. 2009 Apr;30(4):662-70. doi: 10.1093/carcin/bgp042. Epub 2009 Feb 12.
158 Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells. J Neurooncol. 2009 Mar;92(1):15-22. doi: 10.1007/s11060-008-9732-0. Epub 2008 Nov 22.
159 The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells. Leuk Res. 2010 Jul;34(7):899-905. doi: 10.1016/j.leukres.2010.02.004. Epub 2010 Apr 10.
160 Differentiation of human adipose-derived stem cells towards cardiomyocytes is facilitated by laminin. Cell Tissue Res. 2008 Dec;334(3):457-67. doi: 10.1007/s00441-008-0713-6. Epub 2008 Nov 7.
161 Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules. Cancer Immunol Immunother. 2009 Apr;58(4):589-601. doi: 10.1007/s00262-008-0582-6. Epub 2008 Sep 13.
162 Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. J Mol Med (Berl). 2007 Oct;85(10):1137-48. doi: 10.1007/s00109-007-0216-z. Epub 2007 Jun 15.
163 p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma. J Clin Pathol. 2007 Nov;60(11):1249-53. doi: 10.1136/jcp.2006.044099.
164 Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death. J Gastroenterol. 2005 May;40(5):504-10. doi: 10.1007/s00535-005-1576-1.
165 Involvement of epigenetic mechanisms in the regulation of secreted phospholipase A2 expressions in Jurkat leukemia cells. Neoplasia. 2008 Nov;10(11):1195-203. doi: 10.1593/neo.08640.
166 RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma. Cancer. 2006 Dec 15;107(12):2752-9. doi: 10.1002/cncr.22325.
167 Transcriptional activation of steroidogenic factor-1 by hypomethylation of the 5' CpG island in endometriosis. J Clin Endocrinol Metab. 2007 Aug;92(8):3261-7. doi: 10.1210/jc.2007-0494. Epub 2007 May 22.
168 Carbon Nanotube- and Asbestos-Induced DNA and RNA Methylation Changes in Bronchial Epithelial Cells. Chem Res Toxicol. 2019 May 20;32(5):850-860. doi: 10.1021/acs.chemrestox.8b00406. Epub 2019 Apr 23.
169 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer). Biochem Biophys Res Commun. 2006 Dec 15;351(2):455-61. doi: 10.1016/j.bbrc.2006.10.055. Epub 2006 Oct 18.
170 An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment. J Biol Chem. 2008 Feb 1;283(5):2564-74. doi: 10.1074/jbc.M702454200. Epub 2007 Oct 31.
171 Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth. Mol Cancer Ther. 2010 Feb;9(2):336-46. doi: 10.1158/1535-7163.MCT-09-0589. Epub 2010 Feb 2.
172 Additive effects of 5-aza-2'-deoxycytidine and irradiation on clonogenic survival of human medulloblastoma cell lines. Strahlenther Onkol. 2009 May;185(5):331-8. doi: 10.1007/s00066-009-1956-1. Epub 2009 May 15.
173 5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation. Oncogene. 2007 Jan 4;26(1):77-90. doi: 10.1038/sj.onc.1209763. Epub 2006 Jun 26.
174 Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation. Acta Neuropathol. 2009 Apr;117(4):445-56. doi: 10.1007/s00401-009-0494-3. Epub 2009 Feb 12.
175 High expressions of neuronatin isoforms in favorable neuroblastoma. J Pediatr Hematol Oncol. 2007 Aug;29(8):551-6. doi: 10.1097/MPH.0b013e3181256b7b.
176 Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. Exp Eye Res. 2008 Apr;86(4):586-600. doi: 10.1016/j.exer.2008.01.003. Epub 2008 Jan 12.
177 LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors. Epigenetics. 2009 Apr 1;4(3):176-84. doi: 10.4161/epi.4.3.8694. Epub 2009 Apr 6.
178 p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia. Cancer Res. 2008 Nov 15;68(22):9358-66. doi: 10.1158/0008-5472.CAN-08-1860.
179 Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms. Mol Pharmacol. 2009 Nov;76(5):1072-81. doi: 10.1124/mol.109.056291. Epub 2009 Aug 13.
180 Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. Blood. 2009 Mar 19;113(12):2715-22. doi: 10.1182/blood-2008-05-158956. Epub 2008 Dec 18.
181 Inorganic arsenic exposure promotes malignant progression by HDAC6-mediated down-regulation of HTRA1. J Appl Toxicol. 2023 Aug;43(8):1214-1224. doi: 10.1002/jat.4457. Epub 2023 Mar 11.
182 Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer. Int J Cancer. 2007 Aug 1;121(3):547-54. doi: 10.1002/ijc.22705.
183 Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma. Oncogene. 2007 Sep 20;26(43):6332-40. doi: 10.1038/sj.onc.1210461. Epub 2007 Apr 23.
184 Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC). Otolaryngol Head Neck Surg. 2007 Nov;137(5):722-8. doi: 10.1016/j.otohns.2007.07.030.
185 DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell. 2008 Jun;13(6):529-41. doi: 10.1016/j.ccr.2008.04.019.
186 Quantification of regional DNA methylation by liquid chromatography/tandem mass spectrometry. Anal Biochem. 2009 Aug 15;391(2):106-13. doi: 10.1016/j.ab.2009.05.012. Epub 2009 May 12.
187 Promoter CpG methylation in cancer cells contributes to the regulation of MUC4. Br J Cancer. 2009 Jan 27;100(2):344-51. doi: 10.1038/sj.bjc.6604845. Epub 2009 Jan 6.
188 The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors. Oncology. 2006;71(5-6):437-45. doi: 10.1159/000107110. Epub 2007 Aug 9.
189 Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. Carcinogenesis. 2007 Feb;28(2):488-96. doi: 10.1093/carcin/bgl176. Epub 2006 Sep 21.
190 Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. Breast Cancer Res Treat. 2007 Jul;103(3):283-91. doi: 10.1007/s10549-006-9377-7. Epub 2007 Jan 27.
191 Antitumoral activity of liraglutide, a new DNMT inhibitor in breast cancer cells in vitro and in vivo. Chem Biol Interact. 2021 Nov 1;349:109641. doi: 10.1016/j.cbi.2021.109641. Epub 2021 Sep 14.
192 Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression. BMC Cancer. 2008 Nov 7;8:327. doi: 10.1186/1471-2407-8-327.
193 Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer. Int J Cancer. 2014 Mar 15;134(6):1311-22. doi: 10.1002/ijc.28472. Epub 2013 Nov 11.
194 Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res. 2008 Apr 15;68(8):2764-72. doi: 10.1158/0008-5472.CAN-07-6349.
195 MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. Oncotarget. 2016 Mar 22;7(12):14476-85. doi: 10.18632/oncotarget.7507.
196 Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer. Neoplasia. 2014 Dec;16(12):1018-27. doi: 10.1016/j.neo.2014.10.003.
197 PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation. Oncogene. 2007 Dec 13;26(57):7921-32. doi: 10.1038/sj.onc.1210589. Epub 2007 Jun 18.
198 Mechanism of miR-222 and miR-126 regulation and its role in asbestos-induced malignancy. Int J Biochem Cell Biol. 2020 Apr;121:105700. doi: 10.1016/j.biocel.2020.105700. Epub 2020 Feb 4.
199 Aberrant methylation of ADAMTS1 in non-small cell lung cancer. Cancer Genet Cytogenet. 2008 Dec;187(2):80-4. doi: 10.1016/j.cancergencyto.2008.08.001.
200 Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells. FEBS Lett. 2008 Feb 6;582(3):457-67. doi: 10.1016/j.febslet.2008.01.010. Epub 2008 Jan 17.
201 Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. Neoplasia. 2008 Mar;10(3):266-78. doi: 10.1593/neo.07947.
202 Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. Int J Cancer. 2009 Jul 15;125(2):318-27. doi: 10.1002/ijc.24308.
203 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1. Cancer Lett. 2008 Aug 8;266(2):238-48. doi: 10.1016/j.canlet.2008.02.069. Epub 2008 May 21.
204 Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation. Mol Cancer Ther. 2009 Jan;8(1):225-31. doi: 10.1158/1535-7163.MCT-08-0743.
205 Tetrahydrouridine inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels. PLoS One. 2012;7(5):e37424.
206 Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans--toxicological implications. J Toxicol Sci. 2011 Aug;36(4):411-22.
207 ClinicalTrials.gov (NCT02839694) Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy