General Information of Disease (ID: DISQZ2X8)

Disease Name Renal cell carcinoma
Synonyms renal cell adenocarcinoma; kidney adenocarcinoma; hypernephroma; renal cell carcinoma; RCC; renal cell carcinoma (disease)
Disease Class 2C90: Renal cell carcinoma
Definition A carcinoma that arises from glandular epithelial cells of the kidney
Disease Hierarchy
DIS3IHTY: Adenocarcinoma
DISER9XT: Renal carcinoma
DISQZ2X8: Renal cell carcinoma
ICD Code
ICD-11
ICD-11: 2C90
ICD-10
ICD-10: C64
ICD-9
ICD-9: 189
Expand ICD-9
189
Disease Identifiers
MONDO ID
MONDO_0005086
MESH ID
D002292
UMLS CUI
C0007134
MedGen ID
766
HPO ID
HP:0005584
Orphanet ID
217071
SNOMED CT ID
41607009

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 19 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Aldesleukin DM4YMIS Approved NA [1]
Atezolizumab DMMF8U0 Approved Monoclonal antibody [2]
Avelumab DMSZLJR Approved Monoclonal antibody [2]
Axitinib DMGVH6N Approved Small molecular drug [3]
Belzutifan DML1KTO Approved NA [4]
BOL-303259-X DM2EXC5 Approved Small molecular drug [5]
CreaVax-RCC DME7N5P Approved NA [6]
Everolimus DM8X2EH Approved Small molecular drug [7]
Lenvatinib DMB1IU4 Approved Small molecular drug [2]
Nivolumab DMAB9QE Approved Monoclonal antibody [2]
Pazopanib HCl DM6U9CQ Approved Small molecular drug [8]
Pembrolizumab DMFQEA6 Approved Monoclonal antibody [2]
Reniale DMJDDCV Approved NA [9]
Romidepsin DMT5GNL Approved Small molecular drug [10]
Sifalimumab DM1BS03 Approved Antibody [11]
Sorafenib DMS8IFC Approved Small molecular drug [12]
Temsirolimus DMS104F Approved Small molecular drug [13]
Tivozanib DMUKC5L Approved Small molecular drug [14]
HBI-8000 DMDWYUN Registered Small molecular drug [2]
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⏷ Show the Full List of 19 Drug(s)
This Disease is Treated as An Indication in 51 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Human coagulation factor X DMYA6TR BLA submitted NA [15]
Abexinostat DM91LGU Phase 3 Small molecular drug [16]
AM0010 DMGMNUE Phase 3 NA [17]
AMD-070 DMVOY6B Phase 3 Small molecular drug [2]
BMS-986205 DM3MAYQ Phase 3 NA [2]
Cotellic DMF9M57 Phase 3 Small molecular drug [2]
IMA-901 DMV5YI1 Phase 3 NA [18]
NKTR 214 DM376WT Phase 3 NA [17]
Rocapuldencel-T DMRRFLU Phase 3 NA [19]
Savolitinib DMALFKX Phase 3 NA [2]
TKI258 DMYLT67 Phase 3 Small molecular drug [20]
TRC105 DM1874J Phase 3 Monoclonal antibody [17]
Trebananib DMOG2X1 Phase 3 Recombinant protein [21]
Vitespen DMZ8BZ2 Phase 3 NA [22]
CAP-232 DMR6LXM Phase 2a Small molecular drug [23]
AGS-003 DMMNLWI Phase 2 NA [24]
AGS-16C3F DM2POHA Phase 2 NA [2]
Anti-LAG3 DMJO402 Phase 2 NA [17]
ATN-161 DM4T9RS Phase 2 Small molecular drug [25]
Autologous renal cell carcinoma vaccine DM28W2W Phase 2 NA [26]
CB-839 DM094UH Phase 2 NA [2]
CMN-001 DM5WD87 Phase 2 Cell therapy [27]
CRLX101 DMQUWXY Phase 2 NA [2]
DS-3201b DMI69E5 Phase 2 Small molecular drug [28]
FolateImmune DMB9ADM Phase 2 Small molecular drug [29]
Girentuximab I-124 DMG3O2Z Phase 2 Monoclonal antibody [30]
Human interleukin-2 DM0NJWG Phase 2 NA [31]
Ilixadencel DMEUOWB Phase 2 NA [2]
IMO-2055 DM6IQ3V Phase 2 NA [32]
Ispinesib DMP2BWX Phase 2 Small molecular drug [33]
OSI-027 DMJX3O8 Phase 2 Small molecular drug [34]
RX-0201 DMTBAV3 Phase 2 NA [2]
TV-Kidney-1 DMSWGCH Phase 2 NA [19]
TV1-Kidney-1 DMVH0SG Phase 2 NA [35]
TVI-Kidney-1 DMGYSZ0 Phase 2 Vaccine [36]
Varlilumab DMQSC5O Phase 2 NA [2]
XL880 DMHJTR2 Phase 2 Small molecular drug [37]
Anti-C-met CAR-T cells DMV5H0S Phase 1/2 CAR T Cell Therapy [38]
CCT301-38 (targeting ROR2) DM2B1V0 Phase 1/2 CAR T Cell Therapy [39]
CCT301-59 (targeting ROR2) DM0F9CD Phase 1/2 CAR T Cell Therapy [39]
CDX-014 DMBRQ99 Phase 1/2 NA [2]
IL-2 XL DM1CG47 Phase 1/2 NA [40]
LAG525 DMQX5SN Phase 1/2 NA [2]
AGS-16 mab DMD284G Phase 1 Monoclonal antibody [41]
AMG 172 DMS72GN Phase 1 NA [42]
Anti-hCD70 CAR transduced PBL DMK4GIS Phase 1 CAR T Cell Therapy [43]
ARO-HIF2 DMV5PEK Phase 1 Antisense oligonucleotide [44]
Biomed 101 DMQ9KZW Phase 1 Small molecular drug [45]
IL-7/CD80-expressing allogeneic RCC-26 tumor cell vaccine DMW342G Phase 1 NA [46]
Neovastat DMXTYWJ Phase 1 NA [47]
Veglin DM931G7 Phase 1 NA [48]
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⏷ Show the Full List of 51 Drug(s)
This Disease is Treated as An Indication in 1 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Vorsetuzumab mafodotin DMATEL0 Discontinued in Phase 1 Antibody [49]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 4 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
BCL-004 DMRKGMF Investigative NA [50]
GM-CAIX DMJHNBU Investigative NA [50]
GS-168 DMKOA8S Investigative NA [50]
STF-62247 DMPE7DQ Investigative Small molecular drug [50]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 722 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
VHL OT2C3JRN Strong Autosomal dominant [51]
ACD OTC54EPO Limited Biomarker [491]
ACY1 OT9WU7X3 Limited Biomarker [492]
ADIPOR2 OT2HDTL8 Limited Biomarker [493]
AGFG1 OTI8ZKC4 Limited Biomarker [148]
AGO2 OT4JY32Q Limited Biomarker [148]
APLP2 OTTFE53M Limited Altered Expression [494]
ARL4C OTQ3QNNU Limited Biomarker [495]
ARNT OTMSIEZY Limited Biomarker [496]
CA8 OT9Y8GA8 Limited Biomarker [497]
CCN3 OTOW5YL4 Limited Altered Expression [498]
CD82 OTH8MC64 Limited Biomarker [499]
CDCP1 OTD7RRWK Limited Altered Expression [500]
CHCHD2 OTL5PA3Y Limited Biomarker [501]
CHI3L2 OT26R3HQ Limited Altered Expression [502]
CMTM5 OTMS7NDP Limited Biomarker [503]
COL5A1 OT24078H Limited Altered Expression [65]
CORO1A OTVAZOHC Limited Altered Expression [504]
CORO1C OTXDF9T3 Limited Biomarker [505]
CUL5 OTMTZD47 Limited Biomarker [506]
CXCL16 OTD49T9R Limited Biomarker [507]
DCAF1 OT3ZDVOE Limited Biomarker [148]
DCTN4 OTM7C943 Limited Altered Expression [316]
DEFB1 OT5SV0E4 Limited Biomarker [508]
EBAG9 OTTQLQCP Limited Biomarker [509]
ELOC OT0XHHWP Limited Genetic Variation [510]
EN2 OT7EZCM2 Limited Altered Expression [511]
FAM107A OTBG61YZ Limited Posttranslational Modification [512]
FSD1 OT8P6PT3 Limited Biomarker [126]
FSD1L OTBQ48RF Limited Biomarker [126]
FSTL1 OT6KEZUD Limited Biomarker [513]
GTF2H1 OTCRXC6B Limited Altered Expression [316]
HAS1 OTJIAG1W Limited Biomarker [514]
HAVCR1 OT184CRZ Limited Biomarker [515]
HEPACAM OT1MJ51D Limited Altered Expression [516]
HILPDA OTEID3ZM Limited Biomarker [75]
ING4 OT0VVG4V Limited Altered Expression [517]
KDM6A OTZM3MJJ Limited Biomarker [518]
KLLN OTV3FPH0 Limited Altered Expression [519]
KPNA2 OTU7FOE6 Limited Altered Expression [520]
LAMA4 OTHI7TA0 Limited Biomarker [521]
LAT OTZC1XZ1 Limited Biomarker [522]
LMLN OTQF0JPY Limited Posttranslational Modification [87]
MCM3 OTOOHQPM Limited Posttranslational Modification [384]
MICA OTPEIEAR Limited Biomarker [523]
MOK OTQK7M9V Limited Biomarker [524]
MPC1 OT6DYFUO Limited Biomarker [525]
MT1G OTAV1OCR Limited Altered Expression [526]
MT1M OTVT8PLU Limited Posttranslational Modification [526]
NDNF OTCDL9PG Limited Biomarker [527]
NOP53 OTA2YKO6 Limited Altered Expression [528]
NUP62 OTMN63DH Limited Altered Expression [316]
OGT OT1Z1ZXE Limited Altered Expression [529]
PDCD4 OTZ6NXUX Limited Altered Expression [530]
PNRC2 OTE7W7Y5 Limited Biomarker [531]
POLR2A OTHJQ1DZ Limited Altered Expression [532]
PRKAA1 OT7TNF0L Limited Biomarker [92]
PRKAB1 OT1OG4QZ Limited Biomarker [92]
RBM10 OTES2MES Limited Biomarker [533]
RIN1 OTPBROUD Limited Biomarker [534]
RIT1 OTVNOGOH Limited Biomarker [535]
RPAIN OTBMXAYK Limited Biomarker [148]
RWDD3 OTE76DY5 Limited Altered Expression [536]
SCAMP1 OTFS4IKJ Limited Biomarker [537]
SESN2 OT889IXY Limited Biomarker [538]
SFRP1 OT0U9G41 Limited Posttranslational Modification [539]
SFRP5 OTLCVVSH Limited Posttranslational Modification [540]
SOX4 OTSS40SS Limited Biomarker [541]
SPAAR OTWXG2R8 Limited Altered Expression [542]
SPINK13 OTEU2OSU Limited Altered Expression [543]
SPINT2 OTQV7BKQ Limited Biomarker [544]
SRA1 OTYOGMTG Limited Altered Expression [83]
SRL OT7IEBWZ Limited Genetic Variation [545]
STX6 OTC5F5M6 Limited Altered Expression [546]
TIMP3 OTDGQAD1 Limited Biomarker [547]
TMPRSS13 OTMAOAP3 Limited Posttranslational Modification [87]
TNIP1 OTRAOTEW Limited Biomarker [548]
TRIB3 OTG5OS7X Limited Altered Expression [549]
APH1A OT97F1TU Disputed Genetic Variation [132]
COMMD5 OT6R7DXN Disputed Biomarker [550]
SAG OTDNS3ZQ Disputed Altered Expression [551]
ACYP2 OTRB4S6X moderate Genetic Variation [552]
ALDOA OTWRFTIB moderate Altered Expression [553]
ALDOB OT7FR69A moderate Biomarker [554]
AMPD1 OTU17BCI moderate Biomarker [193]
ANXA6 OT9KIQ0Y moderate Biomarker [483]
ARRDC1 OTMCTFHC moderate Biomarker [555]
ARRDC3 OTAKW7R9 moderate Biomarker [555]
ASS1 OT4ZMG0Q moderate Biomarker [148]
AVL9 OTZLRZ55 moderate Biomarker [556]
CAV2 OT1FGRQX moderate Biomarker [557]
CCN4 OT69BER9 moderate Altered Expression [558]
CD151 OTF3UZS7 moderate Biomarker [559]
CDKN2B OTAG24N1 Moderate Autosomal dominant [51]
CIRBP OTXWTPBL moderate Altered Expression [560]
CNPY2 OTGY8ESX moderate Altered Expression [561]
COPS7B OTZEPV2T moderate Biomarker [562]
DAPK1 OTNCNUCO moderate Altered Expression [211]
DIRAS1 OT07F6PE moderate Altered Expression [563]
DLD OT378CU9 moderate Genetic Variation [564]
EEF1A1 OT00THXS moderate Biomarker [565]
ESM1 OT331Y8V moderate Biomarker [566]
ESRP2 OTVTKJ4I moderate Genetic Variation [139]
FAM83H OTN0SF11 moderate Altered Expression [567]
FGB OT6RKLI9 moderate Altered Expression [568]
FNDC5 OT5CSK9X moderate Biomarker [569]
FNIP1 OTB1CC41 moderate Biomarker [570]
FOXK2 OTFXDZ3R moderate Biomarker [571]
GAB2 OTBFN705 moderate Altered Expression [128]
GABPB1 OTEXDEJN moderate Biomarker [572]
GPX4 OTRAFFX2 moderate Biomarker [573]
GTF2H4 OTPD1DIU moderate Altered Expression [145]
HMGN5 OTUUAHVQ moderate Altered Expression [574]
IGFN1 OTJIPVSM moderate Biomarker [575]
KIFC1 OTNQDS00 moderate Biomarker [576]
KLF6 OTQY9S7F moderate Biomarker [577]
LETM1 OT8N4MRU moderate Biomarker [578]
LHX1 OT6WI2XS moderate Biomarker [579]
MAGI1 OTMV4ASV moderate Biomarker [580]
MAN1C1 OT44TM7D moderate Genetic Variation [581]
MAP1LC3B OTUYHB84 moderate Biomarker [582]
MCM2 OTGGORIQ moderate Altered Expression [583]
MCM4 OT19PNNG moderate Altered Expression [583]
MCM5 OTAHLB62 moderate Altered Expression [584]
MIP OTEBLU3E moderate Biomarker [579]
MITF OT6XJCZH Moderate Autosomal dominant [51]
MMUT OTBBBV70 moderate Biomarker [583]
MT1E OTXJKU4Y moderate Posttranslational Modification [526]
MTA2 OTCCYIQJ moderate Biomarker [585]
MUC13 OTWKS9MF moderate Altered Expression [586]
MXD1 OTS5CTHX moderate Biomarker [193]
NANOG OTUEY1FM moderate Biomarker [587]
NCR3 OT20M764 moderate Altered Expression [141]
NR2F2 OTJFS67N moderate Altered Expression [124]
NRK OTGR01FF moderate Biomarker [588]
NRXN3 OTJ0I7HJ moderate Altered Expression [134]
NSD2 OTQ6SW4R moderate Biomarker [589]
NUCB2 OTHO6JWN moderate Biomarker [590]
OPTN OT2UXWH9 moderate Biomarker [591]
PAFAH1B1 OT9T2TCJ moderate Altered Expression [592]
PANX2 OTAQ2S8R moderate Altered Expression [567]
PCBP2 OTXCN9CG moderate Genetic Variation [139]
PCLO OTXJZZ98 moderate Biomarker [593]
PELP1 OTVXQNOT moderate Altered Expression [594]
PIK3R2 OTZSUQK5 moderate Biomarker [595]
PLIN3 OT9ZA7MR moderate Altered Expression [596]
PPP1R12C OT9Q86JO moderate Biomarker [595]
PPP1R13B OTC88VQO moderate Biomarker [595]
PRDX1 OTZ3BEC4 moderate Biomarker [597]
PTEN OTOWDUNT Moderate Autosomal dominant [51]
PYCR1 OTQHB52T moderate Altered Expression [598]
RAB23 OTBAKFBR moderate Altered Expression [599]
RASAL2 OTGMMX6W moderate Biomarker [600]
RASSF6 OT25GVWY moderate Biomarker [601]
RGN OTD04KB1 moderate Biomarker [602]
RTCA OTSJRVTD moderate Biomarker [603]
SARS2 OTU4T99W moderate Biomarker [604]
SCUBE1 OT4JY1UY moderate Biomarker [605]
SDHC OTC8G2MX Moderate Autosomal dominant [51]
SDHD OTYZ8XRH Moderate Autosomal dominant [51]
SELENOW OTVSKPAN moderate Biomarker [606]
SGK2 OTCTVSHF moderate Altered Expression [399]
SGK3 OTQ6QO99 moderate Biomarker [607]
SH3GL2 OTOE443G moderate Biomarker [608]
SLC49A4 OTXL3KAM moderate Biomarker [186]
STIP1 OT7TXLOX moderate Biomarker [609]
TCEA1 OTBFO594 moderate Biomarker [610]
TMEM127 OTYHUXC1 Moderate Autosomal dominant [51]
TMEM52B OTOC70IF moderate Altered Expression [611]
TRPV5 OTWF4L0U moderate Altered Expression [612]
A2ML1 OTWNUXIS Strong Biomarker [613]
AADAC OT8VACT2 Strong Biomarker [614]
ABCA13 OTTHTUQN Strong Altered Expression [615]
ACAT2 OTZ092ZJ Strong Altered Expression [616]
ACCS OTHIHI9D Strong Genetic Variation [617]
ACOT7 OT7C68YV Strong Biomarker [618]
ACSS1 OT6C1WQD Strong Biomarker [478]
ACTBL2 OTD6B81U Strong Biomarker [618]
ACTG2 OTRDWUO0 Strong Biomarker [618]
ADAM28 OT3GBVHL Strong Altered Expression [619]
ADAMTS2 OTTK22NO Strong Biomarker [161]
AHNAK OT6KH1WG Strong Biomarker [231]
AIM2 OT86QUI8 Strong Altered Expression [620]
AKAP13 OTOZAR14 Strong Biomarker [231]
AKT1S1 OT4JHN4Y Strong Biomarker [621]
ALPP OTZU4G9W Strong Biomarker [176]
AMBP OTLU8GU8 Strong Altered Expression [622]
ANAPC16 OTG9MUYS Strong Genetic Variation [150]
ANGPT4 OT881M3K Strong Altered Expression [623]
ANKHD1 OTVYQ7ZL Strong Altered Expression [624]
ANKRD2 OT4UYZ71 Strong Biomarker [625]
ANP32B OT3SQMLU Strong Altered Expression [444]
ANXA4 OTUCRYXL Strong Biomarker [107]
AP1M2 OTUE5YLC Strong Biomarker [391]
AP5M1 OTDLWEBL Strong Biomarker [312]
APAF1 OTJWIVY0 Strong Biomarker [626]
APOBEC3B OTHLNI51 Strong Altered Expression [627]
AQP6 OTXS6UYY Strong Genetic Variation [628]
ARC OTN2QQPG Strong Biomarker [629]
ARHGAP24 OTCQCEZS Strong Biomarker [630]
ARHGDIB OT9PD6CS Strong Altered Expression [631]
ARHGEF5 OTUVGFT9 Strong Biomarker [632]
ASB15 OTI0ZVLJ Strong Biomarker [231]
ASPSCR1 OTXTOD10 Strong Biomarker [633]
ATF2 OTNIZPEA Strong Altered Expression [634]
ATP1B1 OTTO6ZP4 Strong Posttranslational Modification [635]
ATP5MC2 OTA5F480 Strong Genetic Variation [636]
ATRNL1 OTY5JUX2 Strong Biomarker [176]
AXIN2 OTRMGQNU Strong Altered Expression [637]
B3GAT1 OTXFP98E Strong Biomarker [638]
BAP1 OTS8G0EN Strong Autosomal dominant [51]
BAZ1A OTWHOVZS Strong Genetic Variation [314]
BBS2 OTPF9JIB Strong Genetic Variation [639]
BCAR1 OTKT2C2N Strong Biomarker [230]
BHLHE41 OTY9GJ1Y Strong Genetic Variation [640]
BNC1 OTGJ5WUF Strong Biomarker [641]
BNIP3 OT4SO7J4 Strong Altered Expression [642]
BSND OTYWZWPD Strong Altered Expression [643]
BTG3 OT9ANHVT Strong Altered Expression [644]
BUB1B OT8KME51 Strong Altered Expression [193]
C4orf46 OTXL7SLI Strong Posttranslational Modification [645]
CABIN1 OT4G5CIK Strong Genetic Variation [646]
CACYBP OTJMZD2T Strong Biomarker [647]
CADM2 OT45PVKC Strong Biomarker [648]
CALB1 OTM7IXDG Strong Genetic Variation [649]
CAMKMT OTLJBRUW Strong Altered Expression [650]
CAND1 OTGB6NU0 Strong Biomarker [651]
CAPG OTJ86KI6 Strong Biomarker [228]
CARD10 OT2RPM4I Strong Altered Expression [652]
CARD11 OTRCTLYC Strong Biomarker [231]
CAVIN2 OTFHHDRU Strong Altered Expression [653]
CBFA2T2 OTNOIB23 Strong Biomarker [595]
CBLL2 OTB4AD3V Strong Altered Expression [654]
CCAR1 OTUXLQZZ Strong Biomarker [410]
CCDC60 OT9GGLTH Strong Genetic Variation [655]
CCDC8 OTO295IH Strong Genetic Variation [636]
CCL18 OT7JYSK9 Strong Altered Expression [656]
CCL27 OTUZYC61 Strong Biomarker [176]
CCL7 OTDIS99H Strong Altered Expression [657]
CCNC OTMVK4K4 Strong Biomarker [219]
CCNG2 OTII38K2 Strong Biomarker [658]
CD1D OT3ROU4J Strong Altered Expression [659]
CD68 OTOYEY3J Strong Biomarker [660]
CDH15 OTJ1TO02 Strong Biomarker [214]
CDH8 OTS3SRZ6 Strong Biomarker [661]
CDH9 OTV9N5XK Strong Altered Expression [662]
CDHR5 OTTBWQMN Strong Biomarker [663]
CDK2AP2 OTR99SJ8 Strong Genetic Variation [217]
CDKN3 OTBE3H07 Strong Altered Expression [664]
CEACAM7 OTKFDTZY Strong Biomarker [222]
CEMIP OTK80FYN Strong Altered Expression [665]
CENPH OTPOO9LK Strong Biomarker [666]
CEP55 OTGSG2PA Strong Altered Expression [667]
CETN1 OTGQ8JOZ Strong Altered Expression [668]
CHAF1A OTXSSY4H Strong Altered Expression [669]
CHAF1B OTOMK4KH Strong Altered Expression [669]
CHD5 OTS5EVHH Strong Genetic Variation [670]
CHMP1A OTVQ5UWX Strong Biomarker [671]
CHMP1B OTP715L8 Strong Biomarker [672]
CHPT1 OT4FJ0K3 Strong Biomarker [673]
CIB1 OT4BVCRU Strong Biomarker [651]
CIP2A OTVS2GXA Strong Biomarker [674]
CISD3 OT0MM1MW Strong Biomarker [675]
CISH OT8T5NYL Strong Altered Expression [428]
CKS1B OTNUPLUJ Strong Altered Expression [676]
CLDN7 OTNE0XHQ Strong Biomarker [677]
CLDN8 OT7IIWXG Strong Biomarker [678]
CLIP4 OT75KVQK Strong Biomarker [679]
CLTC OTBFASMA Strong Genetic Variation [680]
CMAS OTFQJG3C Strong Altered Expression [681]
CNN2 OTH3CSXA Strong Biomarker [228]
CNOT7 OTJBKCPI Strong Altered Expression [669]
CNOT8 OT6CMCS0 Strong Altered Expression [669]
COL14A1 OTLNJ13O Strong Biomarker [641]
COL15A1 OTTFKK18 Strong Genetic Variation [641]
COL4A3 OT6SB8X5 Strong Altered Expression [682]
COP1 OT6J2K12 Strong Biomarker [683]
CORO6 OT9TFSVB Strong Genetic Variation [636]
CPQ OTTNZNLD Strong Biomarker [265]
CRABP1 OTISDG5X Strong Biomarker [684]
CRABP2 OTY01V9G Strong Altered Expression [685]
CRADD OT02TZ4S Strong Biomarker [200]
CRISP2 OT8HLTV5 Strong Altered Expression [451]
CRYGD OTW29JC4 Strong Biomarker [686]
CSMD3 OTAT75SW Strong Biomarker [312]
CTHRC1 OTV88X2G Strong Biomarker [687]
CTNNA1 OTFC725Z Strong Biomarker [214]
CTNND1 OTUMPSHR Strong Biomarker [230]
CUL1 OTXPE1UZ Strong Biomarker [688]
CXCL5 OTZOUPCA Strong Biomarker [689]
DAB2IP OTF456VC Strong Altered Expression [690]
DACH1 OTMKNAGG Strong Altered Expression [437]
DCTN6 OTI8PIN9 Strong Altered Expression [691]
DDT OTF5HTYL Strong Altered Expression [692]
DDX31 OTNWY581 Strong Altered Expression [693]
DEF6 OTIRBYVK Strong Altered Expression [694]
DEFA1 OT5N1B9B Strong Biomarker [695]
DERL2 OTI3TUUZ Strong Biomarker [696]
DERL3 OTRZRT6Q Strong Genetic Variation [432]
DES OTI09KBW Strong Biomarker [222]
DHDDS OTVLYBUS Strong Biomarker [673]
DKC1 OTX7DJR6 Strong Altered Expression [697]
DKK4 OTWCCVF6 Strong Genetic Variation [97]
DLEC1 OTMKKBUW Strong Biomarker [698]
DNAJB8 OT2CDBH6 Strong Biomarker [244]
DNHD1 OT4U3HUW Strong Biomarker [312]
DPF3 OTEWLMNB Strong Genetic Variation [310]
DSG2 OTJPB2TO Strong Biomarker [699]
DVL2 OTMNYNCM Strong Genetic Variation [700]
DYNLL1 OTR69LHT Strong Biomarker [701]
EEF2 OTZ7SZ39 Strong Biomarker [228]
EIF3C OTR8RF9X Strong Altered Expression [702]
EIF3D OTDOMP80 Strong Biomarker [703]
EIF4B OTE8TXA8 Strong Biomarker [704]
ELF5 OTLRU8YF Strong Altered Expression [705]
ELK1 OTH9MXD6 Strong Biomarker [706]
EOMES OTB9VQFA Strong Altered Expression [707]
EP400 OTVQ75NX Strong Altered Expression [708]
ERCC4 OTFIOPG1 Strong Altered Expression [709]
ERCC6L OTE9V7D9 Strong Biomarker [710]
ESRP1 OTNCS4SL Strong Biomarker [391]
ETV1 OT6PMJIK Strong Altered Expression [683]
FABP7 OTRE2H4G Strong Altered Expression [711]
FAM111B OT9IQ9NV Strong Biomarker [231]
FAM20C OTW5YZ7X Strong Biomarker [712]
FBLN1 OT5MHHOP Strong Altered Expression [713]
FBXO22 OTEJ5MO0 Strong Biomarker [714]
FBXW4 OTEGSZOX Strong Biomarker [614]
FCGR3B OTSLSPZG Strong Altered Expression [715]
FERMT2 OTZNPWWX Strong Biomarker [716]
FGF5 OTQXGHBY Strong Altered Expression [717]
FHL5 OT6C00Z1 Strong Biomarker [618]
FLNB OTPCOYL6 Strong Biomarker [392]
FMN2 OTUY7BSV Strong Biomarker [231]
FOXH1 OTEXJ9SL Strong Altered Expression [718]
FOXI1 OT2UFOE2 Strong Altered Expression [719]
FOXP4 OTHCGIEZ Strong Altered Expression [720]
FPGT OTVZJL3U Strong Biomarker [312]
FRZB OTTO3DPY Strong Biomarker [721]
FZD5 OTXFFY56 Strong Biomarker [722]
FZD8 OTZ9IRFL Strong Altered Expression [723]
GAL3ST1 OTSFFZRD Strong Altered Expression [724]
GALNT2 OTZZ5386 Strong Biomarker [725]
GALNT3 OT7M67WT Strong Altered Expression [726]
GATA5 OTO81B63 Strong Posttranslational Modification [727]
GATM OTIJ4Z11 Strong Altered Expression [325]
GC OTWS63BY Strong Biomarker [728]
GCN1 OTBFVD7Z Strong Genetic Variation [219]
GEMIN4 OTX7402E Strong Genetic Variation [729]
GLIS3 OTBC960E Strong Altered Expression [730]
GNA13 OTVDL515 Strong Biomarker [731]
GNG4 OTOXNDI9 Strong Altered Expression [732]
GOLPH3 OTDLGYM3 Strong Altered Expression [733]
GOT2 OT6XBWN0 Strong Altered Expression [734]
GPSM2 OT6RPMRM Strong Biomarker [278]
GRB7 OTF8Y9XY Strong Biomarker [312]
GRP OT8JDFNI Strong Altered Expression [284]
GSTK1 OTDNGWAF Strong Genetic Variation [342]
GSTM2 OTG4WT05 Strong Biomarker [735]
H4C1 OTB71W46 Strong Biomarker [736]
HARS1 OTHOEOTS Strong Biomarker [228]
HAVCR2 OTOL603T Strong Altered Expression [737]
HIC1 OTI9TWY4 Strong Posttranslational Modification [738]
HIF3A OTPWAAMC Strong Biomarker [739]
HIVEP3 OTM3QT3L Strong Biomarker [740]
HLA-E OTX1CTFB Strong Biomarker [741]
HMMR OT4M0JTZ Strong Altered Expression [742]
HNRNPK OTNPRM8U Strong Biomarker [743]
HNRNPUL1 OTJP4U7K Strong Altered Expression [744]
HOXB1 OTGC0EKI Strong Genetic Variation [745]
HOXB2 OTTD6HMV Strong Genetic Variation [745]
HOXB3 OT9UC5PE Strong Genetic Variation [745]
HOXB4 OTH1HRW5 Strong Genetic Variation [745]
HOXB5 OTU74TB8 Strong Genetic Variation [745]
HOXB6 OT3TFQ0U Strong Genetic Variation [745]
HOXB7 OTC7WYU8 Strong Genetic Variation [745]
HOXB8 OTKHOD17 Strong Genetic Variation [745]
HOXB9 OTMVHQOU Strong Genetic Variation [745]
HOXC11 OT8NMHM6 Strong Biomarker [746]
HSPA1A OTKGIE76 Strong Biomarker [747]
HSPA2 OTSDET7B Strong Biomarker [747]
HSPB7 OTLATAOV Strong Biomarker [748]
HSPH1 OTVRR73T Strong Biomarker [749]
HTRA2 OTC7616F Strong Altered Expression [240]
HTRA3 OTXJ0H4X Strong Biomarker [750]
IFI27 OTI2XGIT Strong Altered Expression [691]
IFNA1 OTPMKY0L Strong Biomarker [751]
IFNA17 OTHXRYG3 Strong Genetic Variation [752]
IGF2BP1 OT9G360P Strong Altered Expression [753]
IGF2BP3 OTB97VIK Strong Altered Expression [754]
IGFBP4 OT2HZRBD Strong Altered Expression [755]
IL10RA OTOX3D1D Strong Biomarker [756]
IL6R OTCQL07Z Strong Biomarker [757]
INHA OT7HWCO3 Strong Altered Expression [758]
INPP4B OTLROA7G Strong Biomarker [759]
INSRR OT3F75WA Strong Biomarker [760]
INTS1 OT7TY1M1 Strong Genetic Variation [761]
IRF9 OTK4MYQJ Strong Biomarker [762]
ITGA2B OT4Y17PY Strong Genetic Variation [763]
ITGA7 OTTBTAYW Strong Altered Expression [764]
JADE1 OTBPJIRI Strong Biomarker [765]
JAM3 OTX0F9QL Strong Biomarker [766]
KANK1 OT2E7A6W Strong Biomarker [767]
KANK2 OT3SZIWM Strong Altered Expression [768]
KAT8 OT5LPQTR Strong Altered Expression [769]
KCNH4 OTHJ8WTU Strong Biomarker [706]
KCNH8 OT3I5FLB Strong Biomarker [706]
KCNIP4 OTB1BS0X Strong Genetic Variation [770]
KDM5D OTEKG0KD Strong Biomarker [771]
KIF1B OTI1XQTO Strong Biomarker [772]
KIF22 OTY6X6BL Strong Biomarker [773]
KLF8 OTUC5CDB Strong Biomarker [774]
KLHL1 OTAX6SAD Strong Altered Expression [469]
KLHL35 OT1DL3FY Strong Genetic Variation [636]
KLK10 OTD573EL Strong Biomarker [322]
KLK11 OT5PKX7Y Strong Altered Expression [775]
KMT2B OTMMAZQX Strong Genetic Variation [80]
KRIT1 OT58AP1I Strong Altered Expression [650]
KRT20 OT4RB40L Strong Biomarker [776]
KRT32 OTZCGZYT Strong Biomarker [312]
KRT72 OTAXW63A Strong Biomarker [777]
KRT8 OTTM4X11 Strong Biomarker [228]
L2HGDH OTW6C712 Strong Altered Expression [518]
LAMTOR2 OTHEDISB Strong Genetic Variation [217]
LATS1 OTOOCG4R Strong Biomarker [778]
LCN1 OT8BWXTV Strong Altered Expression [779]
LDHB OT9B1CT3 Strong Biomarker [228]
LGALS3BP OT9AGQKH Strong Biomarker [780]
LIG1 OTEEQS43 Strong Altered Expression [781]
LIMD1 OTN1CG6R Strong Altered Expression [782]
LMAN2L OTJ9FAWS Strong Biomarker [312]
LRIG1 OTY5HZN5 Strong Altered Expression [781]
LRP1B OT4YZG2N Strong Biomarker [231]
LRPAP1 OT6DVD2Q Strong Biomarker [783]
LRRC3B OT9VDGPR Strong Posttranslational Modification [784]
LRRFIP1 OTN7XAUD Strong Altered Expression [359]
LSAMP OTYXVQX2 Strong Biomarker [785]
LY6G6D OTG75QOC Strong Biomarker [786]
MACF1 OTVIHD77 Strong Genetic Variation [219]
MAD2L2 OT24ZO59 Strong Biomarker [193]
MAGEA9 OTWGX2SD Strong Biomarker [787]
MAGEB2 OTAGUVU5 Strong Altered Expression [788]
MAGED1 OT6EOLFC Strong Altered Expression [788]
MAGT1 OTQSAV5C Strong Altered Expression [167]
MAK16 OTD546E5 Strong Biomarker [789]
MAL2 OTVPEI80 Strong Altered Expression [391]
MAML1 OTQA4DDN Strong Biomarker [790]
MAP1S OT5WUD4C Strong Biomarker [791]
MARCHF8 OTH7PNN2 Strong Biomarker [792]
MARCKSL1 OT13J2FM Strong Biomarker [793]
MAX OTKZ0YKM Strong Biomarker [794]
MB OTYWYL2D Strong Altered Expression [795]
MBD2 OTUQPP0R Strong Biomarker [518]
MCF2L OTEURA8N Strong Genetic Variation [796]
MCPH1 OTYT3TT5 Strong Biomarker [797]
MCRS1 OT8K2X8P Strong Biomarker [798]
MED12 OTQZ4D2X Strong Biomarker [799]
MED15 OT0D0JVD Strong Genetic Variation [800]
MED8 OTSIZ1I7 Strong Altered Expression [799]
METTL3 OTSXP1M3 Strong Altered Expression [801]
MFAP1 OTZN4FT3 Strong Biomarker [338]
MGP OTZWU3FU Strong Altered Expression [802]
MIB1 OT5C404P Strong Altered Expression [350]
MINDY4 OTBZ2SZB Strong Altered Expression [196]
MLLT10 OTURMDV7 Strong Biomarker [312]
MLXIP OT30UNI7 Strong Biomarker [792]
MRPL41 OTG5URO4 Strong Biomarker [803]
MSGN1 OTZGNRKZ Strong Biomarker [312]
MT1H OT0MVBM6 Strong Biomarker [487]
MTG1 OTC9U1LI Strong Biomarker [804]
MTHFD2 OT1LQSGX Strong Posttranslational Modification [805]
MUC3A OTI4XUDY Strong Altered Expression [357]
MUC4 OTLT11V1 Strong Biomarker [312]
MUL1 OT2JC9YR Strong Biomarker [806]
MXRA5 OTXZBWCU Strong Altered Expression [807]
MYH9 OT94Z706 Strong Biomarker [808]
MYL2 OT78PC0C Strong Biomarker [732]
MYL9 OT6B22JB Strong Biomarker [732]
MYLIP OTL0PFGV Strong Biomarker [792]
MYO7B OTOQ6S1H Strong Genetic Variation [150]
NAPSA OT6F8IAL Strong Altered Expression [809]
NAV3 OT97M1TR Strong Biomarker [231]
NBN OT73B5MD Strong Genetic Variation [810]
NCOA6 OTOMIGTV Strong Biomarker [811]
ND3 OT1OC3K3 Strong Biomarker [812]
NDRG1 OTVO66BO Strong Biomarker [228]
NDRG2 OT5L6KD7 Strong Biomarker [254]
NEFH OTMSCW5I Strong Posttranslational Modification [813]
NELL2 OTS4MJZ7 Strong Biomarker [814]
NEU1 OTH9BY8Y Strong Altered Expression [815]
NEU3 OTQ5PQOW Strong Biomarker [816]
NEURL1 OT2C4P70 Strong Altered Expression [815]
NFATC1 OT4TMERS Strong Biomarker [104]
NFIA OTDHQ9CG Strong Altered Expression [817]
NFIC OTLMCUIB Strong Altered Expression [817]
NLRP12 OTGR132Z Strong Biomarker [312]
NLRP2 OTJA81JU Strong Biomarker [810]
NME2 OTCYGLHV Strong Altered Expression [818]
NOL3 OT1K0L0D Strong Altered Expression [819]
NONO OTN36Q6U Strong Genetic Variation [820]
NPC2 OTE9UEJC Strong Altered Expression [821]
NSG1 OTRIMA50 Strong Altered Expression [822]
NT5C1A OTS7UF36 Strong Genetic Variation [646]
NUB1 OTWA6RTX Strong Biomarker [823]
NUDCD1 OT8DS3CX Strong Altered Expression [592]
NUSAP1 OT85HIJ5 Strong Biomarker [824]
NXF1 OTEFHXG6 Strong Biomarker [392]
OBP2A OTBIJ5TI Strong Biomarker [773]
OSR1 OTB19LEQ Strong Biomarker [825]
P3H4 OTZPXYSH Strong Biomarker [826]
PACC1 OTKBS8CC Strong Biomarker [827]
PARD3 OTH5BPLO Strong Biomarker [264]
PAX8 OTRPD9MI Strong Biomarker [828]
PCDH17 OTRK0M05 Strong Biomarker [829]
PCDH8 OTDDOQM2 Strong Biomarker [830]
PCLAF OTMVIOUU Strong Altered Expression [831]
PDC OT1UUVYY Strong Genetic Variation [832]
PDHB OT2NHE5E Strong Biomarker [265]
PDLIM3 OTVXQC81 Strong Biomarker [176]
PDXDC1 OTKH7U5Q Strong Biomarker [265]
PDZD2 OTPPVRGY Strong Genetic Variation [833]
PEA15 OTKCKTSX Strong Altered Expression [834]
PFN1 OTHTGA1H Strong Altered Expression [835]
PIAS2 OTJLSC3V Strong Altered Expression [836]
PIDD1 OTWFM930 Strong Biomarker [200]
PIP OTH719AH Strong Biomarker [837]
PITX1 OTA0UN4C Strong Biomarker [838]
PLA2G15 OT6VJTPA Strong Genetic Variation [617]
PLCL1 OTJL2C79 Strong Biomarker [839]
PLIN2 OTRXJ9UN Strong Biomarker [840]
PMAIP1 OTXEE550 Strong Biomarker [841]
PNKD OT6G9UXN Strong Biomarker [265]
PNO1 OT010GIS Strong Biomarker [789]
POGLUT3 OTBTJI73 Strong Genetic Variation [150]
POT1 OTNBXJCQ Strong Genetic Variation [150]
POTEM OT7L2HGH Strong Biomarker [618]
POU2F2 OTPV0J0C Strong Biomarker [422]
POU3F2 OT30NFOC Strong Altered Expression [817]
PPBP OT1FHGQS Strong Biomarker [842]
PPFIA4 OTWXG0DO Strong Altered Expression [843]
PRDM2 OT8L7CGX Strong Altered Expression [844]
PRKX OTDAC6Z0 Strong Altered Expression [845]
PROM2 OTT8IVS7 Strong Biomarker [391]
PRPF31 OTSJ0Z1Y Strong Biomarker [183]
PRSS55 OTXXWI5Y Strong Altered Expression [451]
PSG2 OT2EIXAI Strong Biomarker [222]
PSMD9 OT6Y5CC3 Strong Altered Expression [691]
PSME3 OTSTC4YY Strong Biomarker [121]
PTHLH OTI1JF13 Strong Biomarker [846]
PTPRG OT9N2WOF Strong Genetic Variation [471]
PTPRT OTV5TXNN Strong Biomarker [847]
PTPRU OTHDO0QG Strong Genetic Variation [471]
PVALB OTZW1WVQ Strong Biomarker [848]
PXN OTVMMUOF Strong Altered Expression [849]
PYROXD2 OTJIX22S Strong Altered Expression [850]
QRSL1 OTJDU2UG Strong Genetic Variation [727]
RAB25 OTW0W6NP Strong Biomarker [225]
RAB37 OTRL8IUO Strong Biomarker [851]
RAB5A OTFR2KM4 Strong Altered Expression [852]
RAG2 OTG9UYTW Strong Biomarker [853]
RALGAPB OTY8CGA3 Strong Biomarker [613]
RALYL OT232N7Q Strong Altered Expression [854]
RAN OT2TER5M Strong Altered Expression [855]
RAP1B OTHEIIMM Strong Biomarker [856]
RAP1GAP OTC31ONQ Strong Altered Expression [857]
RAP2B OTD2NDQP Strong Biomarker [858]
RAPGEF5 OT53VS75 Strong Biomarker [859]
RARRES1 OTETUPP5 Strong Altered Expression [860]
RASSF5 OT6Q41I2 Strong Biomarker [785]
RBM14 OTO9GMBD Strong Altered Expression [861]
RBM38 OTPO8EXU Strong Biomarker [862]
RBMS3 OTFSC9MR Strong Biomarker [789]
RBP1 OTRP1MFC Strong Biomarker [684]
RBP2 OTR8QG5V Strong Altered Expression [685]
RBX1 OTYA1UIO Strong Biomarker [863]
RCC1 OT25AGMB Strong Altered Expression [864]
RETN OTW5Z1NH Strong Altered Expression [865]
RGS5 OTUY0Q2I Strong Biomarker [866]
RHEB OTFLTSEC Strong Genetic Variation [365]
RHOBTB2 OT2DATFX Strong Genetic Variation [150]
RING1 OTCWTAX0 Strong Biomarker [867]
RIOX2 OT2YFPI2 Strong Altered Expression [868]
RIT2 OTSNYG0D Strong Biomarker [869]
RNASE3 OTVE2XD1 Strong Biomarker [870]
RNASEH2A OT8G3G7K Strong Altered Expression [871]
RNF121 OTA0YMLW Strong Biomarker [872]
RNF125 OTBD1Q3X Strong Biomarker [873]
RNF139 OT0PR1X5 Strong Biomarker [874]
RPL14 OTZZW7TK Strong Biomarker [312]
RPL17 OTTYMPS6 Strong Altered Expression [875]
RPP14 OT4OYFSK Strong Genetic Variation [217]
RPS15A OT0BUA12 Strong Biomarker [876]
RPS6 OTT4D1LN Strong Altered Expression [877]
RTL10 OTHGB81W Strong Biomarker [878]
S100A1 OT1F2G4J Strong Biomarker [879]
S100A10 OTI71243 Strong Biomarker [276]
S100A11 OTI57KDN Strong Biomarker [880]
S100A5 OTCGGL6K Strong Altered Expression [881]
SAGE1 OT4H6FFA Strong Altered Expression [882]
SART1 OTHMOGO1 Strong Biomarker [263]
SAV1 OTSAEV92 Strong Altered Expression [883]
SCNN1B OT61QQTL Strong Posttranslational Modification [437]
SCUBE3 OT2EADLC Strong Genetic Variation [636]
SCYL1 OTQ0IN7P Strong Biomarker [884]
SDC3 OT1P0LJM Strong Biomarker [885]
SDF4 OTQ7WFYW Strong Altered Expression [668]
SDHA OTOJ8QFF Strong Genetic Variation [429]
SDHB OTRE1M1T Strong Autosomal dominant [51]
SDS OT5WTJ2M Strong Genetic Variation [429]
SEC14L2 OTJST64D Strong Biomarker [392]
SELENOM OTJ7PORS Strong Biomarker [886]
SEMG1 OT6Z4BPQ Strong Altered Expression [887]
SERPINA5 OTTZXPGD Strong Genetic Variation [888]
SET OTGYYQJO Strong Altered Expression [889]
SETDB2 OTBVVP9Q Strong Altered Expression [868]
SF3B2 OTNW2U4Y Strong Genetic Variation [365]
SF3B6 OTPRKS6S Strong Genetic Variation [217]
SFMBT1 OTKMZIBW Strong Biomarker [314]
SFPQ OTLCIAPJ Strong Genetic Variation [890]
SFRP2 OT8GZ0CA Strong Biomarker [614]
SH3BP2 OT90JNBS Strong Altered Expression [419]
SHANK1 OTK8PV0S Strong Biomarker [231]
SHOX2 OTLCZZJW Strong Altered Expression [891]
SIX2 OTYOVGSC Strong Altered Expression [892]
SKA1 OTDYJ12A Strong Altered Expression [893]
SLC12A9 OTR7VRAK Strong Biomarker [894]
SLC16A4 OT1YXBKC Strong Altered Expression [330]
SLC22A18 OT9C3KR4 Strong Genetic Variation [895]
SLC35G2 OTFBVS0P Strong Biomarker [851]
SLFN5 OTT1AESL Strong Altered Expression [896]
SLPI OTUNFUU8 Strong Biomarker [176]
SMAD2 OTC6VB4K Strong Biomarker [897]
SMARCA1 OT0Y6PTU Strong Altered Expression [898]
SMARCB1 OT2LP7LJ Strong Biomarker [899]
SMG1 OTTS3SXE Strong Altered Expression [256]
SMUG1 OT2YIOCQ Strong Biomarker [900]
SMURF2 OT3TRVL7 Strong Biomarker [901]
SNAI2 OT7Y8EJ2 Strong Biomarker [902]
SOX7 OTOZOFAG Strong Biomarker [903]
SPAG4 OTVXS2SM Strong Biomarker [904]
SPAG9 OT45AHMB Strong Biomarker [905]
SPARCL1 OT74DWMV Strong Altered Expression [906]
SPATA2 OTOA45GL Strong Altered Expression [875]
SPEN OT37A2MD Strong Biomarker [675]
SPINK1 OTSUVAL2 Strong Biomarker [907]
SPINT1 OT1CLR5L Strong Biomarker [287]
SPOP OTP0107S Strong Biomarker [908]
SPRY2 OTH0CRCZ Strong Biomarker [909]
SPTBN4 OTAJAVP9 Strong Biomarker [231]
SPTLC1 OTN0Z98K Strong Biomarker [910]
SPZ1 OTQH8HJ5 Strong Altered Expression [451]
SRRM2 OTSIMMC9 Strong Biomarker [789]
SRXN1 OTYDBO4L Strong Biomarker [911]
SSH2 OT8NCK82 Strong Altered Expression [912]
ST3GAL2 OT8WM21E Strong Altered Expression [913]
ST3GAL4 OTNENJZQ Strong Altered Expression [914]
STAG1 OT564IX4 Strong Altered Expression [915]
STAMBPL1 OTI4CYTF Strong Altered Expression [916]
STEAP3 OTS9GZK5 Strong Genetic Variation [310]
STK3 OTLNSCQD Strong Biomarker [917]
STRN OTLOZL5I Strong Biomarker [153]
SUB1 OTK71JYU Strong Genetic Variation [217]
SUSD2 OTSJTAZP Strong Biomarker [918]
SYCE1L OTXU44F3 Strong Altered Expression [469]
SYNE2 OTBUXGQ0 Strong Biomarker [231]
SYT6 OTE3F36L Strong Altered Expression [437]
TAP2 OTWSYFI7 Strong Posttranslational Modification [919]
TAPBP OTL81AVZ Strong Biomarker [392]
TBC1D8 OT2011SS Strong Biomarker [920]
TBC1D9 OTSSCTB5 Strong Altered Expression [465]
TBPL1 OT4I143E Strong Altered Expression [436]
TBX3 OTM64N7K Strong Altered Expression [921]
TCEAL1 OTAPG2L5 Strong Altered Expression [822]
TCF21 OT393IMA Strong Biomarker [319]
TCHP OTVDMHSY Strong Biomarker [922]
TESC OTI8C76M Strong Altered Expression [99]
TET1 OTZDHT1D Strong Biomarker [923]
TET2 OTKKT03T Strong Biomarker [312]
TET3 OT76U3YF Strong Biomarker [924]
TFAP2B OTR1T8E9 Strong Altered Expression [925]
TFCP2L1 OT7QIJ0X Strong Altered Expression [926]
TFDP2 OTKQFX5H Strong Genetic Variation [150]
TFEB OTJUJJQY Strong Genetic Variation [927]
TGFBI OTR443C5 Strong Altered Expression [928]
TGFBR3 OTQOOUC4 Strong Altered Expression [707]
TICAM2 OTK7GIJ5 Strong Altered Expression [691]
TIMELESS OTD8DCBJ Strong Biomarker [632]
TIMP4 OT8A68SW Strong Altered Expression [929]
TM7SF2 OTILU5S7 Strong Altered Expression [930]
TMED7 OTONO8E6 Strong Altered Expression [691]
TMED9 OTYGAQS0 Strong Genetic Variation [217]
TMEFF2 OT1WZ2QO Strong Posttranslational Modification [931]
TMEM176B OTEGF2BV Strong Altered Expression [694]
TMEM45A OT54KJG6 Strong Altered Expression [932]
TMSB10 OTLVZ13T Strong Biomarker [933]
TNFRSF6B OTKAN9G7 Strong Altered Expression [934]
TNS3 OTPG2D8Z Strong Altered Expression [935]
TP53I3 OTSCM68G Strong Biomarker [803]
TP53INP1 OT2363Z9 Strong Altered Expression [768]
TP73 OT0LUO47 Strong Altered Expression [936]
TPD52 OTPKSK43 Strong Biomarker [937]
TPM1 OTD73X6R Strong Altered Expression [938]
TPM3 OT5RU5G6 Strong Genetic Variation [939]
TPPP OTCFMSUF Strong Genetic Variation [217]
TRAF1 OTTLM5RU Strong Biomarker [940]
TRAM1 OT3I0H8E Strong Altered Expression [941]
TRIM33 OT0KS4J7 Strong Altered Expression [942]
TRIM9 OTKYG33W Strong Altered Expression [943]
TRIP11 OT4FJEAR Strong Altered Expression [102]
TSACC OT3QW6PH Strong Altered Expression [768]
TSC1 OTFF4YZ7 Strong Genetic Variation [146]
TTBK2 OT90YSM5 Strong Altered Expression [845]
DLC1 OTP8LMCR Definitive Biomarker [701]
FNIP2 OT7EX8JJ Definitive Biomarker [944]
MST1 OTOC4UNG Definitive Posttranslational Modification [87]
NDUFS1 OTTIZDFR Definitive Altered Expression [945]
PGK1 OT6V1ICH Definitive Altered Expression [946]
PRCC OTJ0KRYX Definitive Genetic Variation [127]
RELA OTUJP9CN Definitive Biomarker [145]
SARDH OTQ49Q27 Definitive Genetic Variation [545]
STK11 OT1YZSP3 Definitive Biomarker [947]
TSC2 OT47LWI9 Definitive Genetic Variation [146]
------------------------------------------------------------------------------------
⏷ Show the Full List of 722 DOT(s)
This Disease Is Related to 469 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCC1 TTOI92F Limited Biomarker [52]
ABCG2 TTIMJ02 Limited Posttranslational Modification [53]
ADAM10 TTVXEGU Limited Biomarker [54]
ALOX12B TTQ4QQH Limited Biomarker [55]
AMACR TTLN1AP Limited Biomarker [56]
APLNR TTJ8E43 Limited Biomarker [57]
AURKA TTPS3C0 Limited Altered Expression [58]
BIRC5 TTTPU1G Limited Altered Expression [59]
CDH2 TT1WS0T Limited Altered Expression [60]
CDH5 TTXLCFO Limited Biomarker [61]
CDH6 TT9QHUK Limited Altered Expression [62]
CEBPB TTUI35N Limited Altered Expression [63]
CFLAR TTJZQYH Limited Biomarker [64]
COL6A3 TT5WCAH Limited Altered Expression [65]
CTSG TTQAJF1 Limited Biomarker [66]
DKK2 TTST5KX Limited Altered Expression [67]
EDNRB TT3ZTGU Limited Altered Expression [68]
ESRRA TTPNQAC Limited Biomarker [69]
ESRRG TT9ZRHB Limited Biomarker [70]
FBXW7 TT29KY7 Limited Biomarker [71]
FGFR3 TTST7KB Limited Altered Expression [72]
FKBP10 TT4P8O2 Limited Biomarker [73]
HIPK2 TTOB49C Limited Altered Expression [74]
HLA-A TTHONFT Limited Biomarker [75]
HPGDS TTCYE56 Limited Genetic Variation [76]
IFNB1 TT4TZ8J Limited Biomarker [77]
IMP3 TTEJA2R Limited Altered Expression [78]
KAT6A TT6O1J0 Limited Biomarker [79]
KDM5C TT94UCF Limited Genetic Variation [80]
KIF20B TTQECT2 Limited Biomarker [81]
LAIR1 TTSI7A8 Limited Biomarker [82]
LOXL2 TTFSUHX Limited Altered Expression [83]
MAP4K1 TTSHWUP Limited Genetic Variation [84]
MKNK1 TTEZAUX Limited Biomarker [85]
MLH1 TTISG27 Limited Biomarker [86]
MSMB TTYH1ZK Limited Posttranslational Modification [87]
NEDD9 TT1UREA Limited Biomarker [88]
NPTX2 TTNJ5A6 Limited Altered Expression [89]
NT5E TTK0O6Y Limited Biomarker [90]
PDK1 TTCZOF2 Limited Altered Expression [91]
PDPK1 TTYMGWX Limited Biomarker [91]
PKM TT4LOT8 Limited Biomarker [92]
PSMD10 TT2H4LN Limited Biomarker [93]
RBCK1 TTIKUVC Limited Altered Expression [94]
RCVRN TTDQTEY Limited Altered Expression [95]
S1PR1 TT9JZCK Limited Biomarker [96]
SFRP4 TTX8I1Y Limited Genetic Variation [97]
SLC5A2 TTF8JAT Limited Biomarker [98]
SLC9A1 TTGSEFH Limited Biomarker [99]
SOX5 TTXHSZK Limited Biomarker [100]
SRPK1 TTU3WV6 Limited Biomarker [101]
THRB TTGER3L Limited Biomarker [102]
TLR1 TTW14D0 Limited Biomarker [103]
TRPC6 TTRBT3W Limited Biomarker [104]
TSG101 TTHU7JA Limited Altered Expression [105]
UCP1 TTI12YJ Limited Altered Expression [106]
HSPB1 TT9AZWY Disputed Biomarker [107]
IFNA2 TTSIUJ9 Disputed Biomarker [108]
PAK1 TTFN95D Disputed Altered Expression [109]
SOD2 TT9O4C5 Disputed Altered Expression [110]
ACLY TT0Z6Y2 moderate Altered Expression [111]
ACVRL1 TTGYPTC moderate Biomarker [112]
ADORA2A TTM2AOE moderate Biomarker [113]
ALOX5 TTSJ6Q4 moderate Biomarker [55]
APLN TT87D3J moderate Biomarker [57]
ARG2 TTV1AG6 moderate Biomarker [114]
ARRB2 TT8SO2I moderate Biomarker [115]
ASIC2 TTVMWLP moderate Biomarker [116]
ATF4 TTQCKWT moderate Biomarker [117]
BCL2A1 TTGT9C7 moderate Altered Expression [111]
CBL TT7QT13 moderate Altered Expression [118]
CCND1 TTFCJ7S moderate Biomarker [119]
CCNE1 TTCEJ4F moderate Altered Expression [120]
CSNK1E TTA8PLI moderate Biomarker [121]
CXCR1 TTMWT8Z moderate Altered Expression [122]
DCLK1 TTOHTCY moderate Biomarker [123]
ESRRB TTKF0XS moderate Biomarker [124]
F2RL3 TTD0652 moderate Biomarker [125]
FN1 TTPJ921 moderate Biomarker [126]
GPNMB TT7315J moderate Biomarker [127]
GRB2 TTEYRJ9 moderate Altered Expression [128]
GRM4 TTICZ1O moderate Genetic Variation [129]
HNF1A TT01M3K moderate Biomarker [130]
HOXA11 TTEX4ZA moderate Altered Expression [131]
IGFBP7 TTUQ01B moderate Genetic Variation [132]
IRF1 TT4TU3L moderate Biomarker [133]
ITGB8 TTIF29E moderate Altered Expression [134]
KDM1B TT8VP2T moderate Biomarker [135]
KDM5A TTIG67W moderate Biomarker [135]
KEAP1 TT3Z6Y9 moderate Altered Expression [136]
LAMP2 TTULDG7 moderate Altered Expression [137]
MAPK12 TTYT93M moderate Altered Expression [138]
MBNL2 TTH9OLG moderate Biomarker [139]
MCAM TTHRE05 moderate Biomarker [140]
NCR1 TTQNRJM moderate Altered Expression [141]
PDE10A TTJW4LU moderate Altered Expression [142]
PLD2 TTRLMKF moderate Biomarker [143]
PPM1D TTENJAB moderate Biomarker [144]
PSIP1 TTH9LDP moderate Altered Expression [145]
PTEN TTEUQ4M Moderate Autosomal dominant [51]
PTEN TTXJ3W7 moderate Altered Expression [146]
RCE1 TT2AP5B moderate Altered Expression [147]
RIPK1 TTVJHX8 moderate Biomarker [148]
RRM2 TT1S4LJ moderate Biomarker [149]
SCARB1 TTRE324 moderate Genetic Variation [150]
SDHD TTVH9W8 Moderate Autosomal dominant [51]
SENP1 TTW9HY5 moderate Altered Expression [151]
SETD2 TTPC3H4 moderate Biomarker [152]
SLC22A3 TTG2UMS moderate Altered Expression [153]
ST8SIA4 TTDP8YM moderate Altered Expression [154]
STC1 TTDLUER moderate Altered Expression [155]
STK39 TTYQTIU moderate Altered Expression [156]
ABCC2 TTFLHJV Strong Genetic Variation [157]
ACR TTAHE2N Strong Biomarker [158]
ACVR1 TTJNBQA Strong Biomarker [159]
ACVR2B TTLFRKS Strong Biomarker [160]
ADAM8 TTQWYMD Strong Altered Expression [161]
ADAM9 TTTYQNS Strong Biomarker [162]
ADAMTS1 TTS2TEI Strong Altered Expression [161]
ADORA1 TTK25J1 Strong Biomarker [163]
AKR1C3 TT5ZWB6 Strong Altered Expression [164]
ALAD TTJHKYD Strong Biomarker [165]
ALOX12 TT12ABZ Strong Altered Expression [166]
ALOX15 TTN9T81 Strong Altered Expression [166]
ALPI TTHYMUV Strong Altered Expression [167]
AMOT TTI48OS Strong Biomarker [168]
ANG TTURHFP Strong Altered Expression [169]
ANGPTL3 TT59GO7 Strong Biomarker [170]
ANGPTL4 TTWALY5 Strong Biomarker [171]
ANXA1 TTUCK4B Strong Biomarker [172]
ANXA2 TT4YANI Strong Altered Expression [173]
APEH TTYWEDQ Strong Genetic Variation [174]
APOL1 TTDB8PW Strong Biomarker [175]
AR TTKPW01 Strong Biomarker [148]
ASRGL1 TT4WT91 Strong Biomarker [176]
ATG7 TTLVB9Z Strong Altered Expression [177]
ATIC TT9NVXQ Strong Biomarker [178]
ATP1A1 TTWK8D0 Strong Biomarker [179]
AXL TTZPY6J Strong Altered Expression [180]
B2M TTY7FKA Strong Biomarker [181]
BAP1 TT47RXJ Strong Autosomal dominant [51]
BBC3 TT7JUKC Strong Altered Expression [182]
BCL2L2 TTQ79W8 Strong Altered Expression [183]
BIRC2 TTQ5LRD Strong Altered Expression [184]
BIRC7 TTHZ8TA Strong Biomarker [185]
BMP6 TT07RIB Strong Biomarker [186]
BMPR2 TTGKF90 Strong Altered Expression [187]
BMX TTN2I9E Strong Altered Expression [188]
BSG TT5UJWD Strong Biomarker [189]
BST2 TT90BJT Strong Altered Expression [190]
BTG1 TTL7N2W Strong Biomarker [191]
BTLA TTER58P Strong Genetic Variation [192]
BUB1 TT78309 Strong Altered Expression [193]
C1QBP TTWTD7F Strong Biomarker [194]
CA12 TTSYM0R Strong Altered Expression [195]
CA4 TTZHA0O Strong Altered Expression [196]
CA9 TT2LVK8 Strong Biomarker [197]
CAPN1 TT1WBIJ Strong Altered Expression [198]
CAPN2 TTG5QB7 Strong Altered Expression [199]
CASP2 TT12VNG Strong Biomarker [200]
CCNB1 TT9P6OW Strong Biomarker [201]
CCND3 TT1JXNR Strong Biomarker [202]
CCR3 TTD3XFU Strong Biomarker [203]
CD209 TTBXIM9 Strong Biomarker [204]
CD24 TTCTYNP Strong Altered Expression [205]
CD276 TT6CQUM Strong Altered Expression [206]
CD38 TTPURFN Strong Biomarker [207]
CD3E TTZAT79 Strong Altered Expression [208]
CD70 TTNCIE0 Strong Biomarker [209]
CD74 TTCMYP9 Strong Biomarker [210]
CDC20 TTBKFDV Strong Altered Expression [211]
CDC25B TTR0SWN Strong Altered Expression [212]
CDH11 TTRGWZC Strong Biomarker [213]
CDH3 TTARMD9 Strong Biomarker [214]
CDK1 TTH6V3D Strong Biomarker [215]
CDK2 TT7HF4W Strong Biomarker [216]
CDK5R1 TTBYM6V Strong Genetic Variation [217]
CDK7 TTQYF7G Strong Biomarker [218]
CDK8 TTBJR4L Strong Genetic Variation [219]
CDKN2A TTFTWQ8 Strong Altered Expression [220]
CEACAM1 TTA9CK4 Strong Altered Expression [221]
CEACAM3 TTPX7I5 Strong Biomarker [222]
CGB3 TTUH273 Strong Altered Expression [223]
CLN3 TTORF9W Strong Altered Expression [190]
COPS5 TTSTNJR Strong Biomarker [224]
CRHBP TT3PKZE Strong Biomarker [225]
CRHR2 TTIY658 Strong Biomarker [226]
CRP TTWRN6M Strong Altered Expression [227]
CRYAB TT7RUHB Strong Biomarker [228]
CRYZ TTP6UO8 Strong Biomarker [229]
CSE1L TTTRULD Strong Biomarker [230]
CTSB TTF2LRI Strong Biomarker [228]
CTSD TTPT2QI Strong Biomarker [228]
CUL7 TTI8R0P Strong Biomarker [231]
CXCL11 TTWG0RE Strong Biomarker [232]
CXCL9 TTWE5PB Strong Biomarker [232]
CXCR2 TT30C9G Strong Altered Expression [233]
CXCR3 TT1UCIJ Strong Biomarker [234]
CYP1B1 TTI84H7 Strong Altered Expression [235]
CYP24A1 TT82UI1 Strong Biomarker [236]
CYP3A5 TTHS0OK Strong Biomarker [237]
DAAM2 TTN0Z6H Strong Genetic Variation [97]
DDC TTN451K Strong Altered Expression [238]
DFFA TTYVQ9C Strong Altered Expression [239]
DIABLO TTN74LE Strong Altered Expression [240]
DKK3 TTY2ZV6 Strong Altered Expression [241]
DLK1 TTF4AVB Strong Posttranslational Modification [242]
DLL1 TT9CFQD Strong Altered Expression [243]
DNAJB1 TTPXAWS Strong Biomarker [244]
DRD1 TTZFYLI Strong Altered Expression [245]
DUSP9 TT1GV6C Strong Altered Expression [246]
E2F1 TTASI04 Strong Biomarker [247]
E2F3 TTWIJYH Strong Biomarker [248]
EBP TT4VQZX Strong Biomarker [249]
ECE1 TTQ9RYT Strong Altered Expression [250]
EDN2 TTMR0OP Strong Biomarker [251]
EGFL7 TT7WD0H Strong Biomarker [252]
EIF2AK3 TT79U1M Strong Altered Expression [253]
EIF4EBP1 TTKGEBL Strong Altered Expression [254]
ENPEP TT9PBIL Strong Biomarker [255]
ENPP2 TTSCIM2 Strong Altered Expression [256]
ENPP3 TTD4TKP Strong Biomarker [257]
EPHA2 TTRJB2G Strong Altered Expression [258]
EPHA3 TTHS2LR Strong Biomarker [259]
EPHB4 TTI4ZX2 Strong Altered Expression [260]
EPOR TTAUX24 Strong Biomarker [261]
ERAP2 TTVGS1C Strong Altered Expression [262]
F12 TTRJSMV Strong Biomarker [263]
F2RL2 TTVSEBF Strong Biomarker [264]
FAAH2 TTWTES7 Strong Biomarker [265]
FAF1 TTSKL3G Strong Genetic Variation [150]
FBXO11 TT6G10V Strong Altered Expression [266]
FHIT TTMS54D Strong Genetic Variation [267]
FKBP1A TTMW94E Strong Biomarker [268]
FLT1 TT1VAUK Strong Biomarker [269]
FOLH1 TT9G4N0 Strong Genetic Variation [270]
FSCN1 TTTRS9B Strong Biomarker [271]
FTH1 TT975ZT Strong Altered Expression [272]
FZD7 TTUQMO5 Strong Biomarker [273]
G3BP1 TTG0R8Z Strong Altered Expression [274]
GAD1 TTKGEP3 Strong Biomarker [275]
GAS6 TT69QD2 Strong Biomarker [276]
GHSR TTWDC17 Strong Biomarker [277]
GNAI1 TTL1HWR Strong Biomarker [278]
GNAO1 TTAXD8Z Strong Biomarker [278]
GNE TT4DP5S Strong Biomarker [279]
GPBAR1 TTSDVTR Strong Altered Expression [280]
GPR182 TTT23CG Strong Biomarker [281]
GRK5 TTTCXO0 Strong Biomarker [282]
GRM1 TTVBPDM Strong Biomarker [283]
GRPR TTC1MVT Strong Altered Expression [284]
GSK3A TTQWAU1 Strong Biomarker [285]
GSTO1 TTWO3SH Strong Genetic Variation [286]
HDAC1 TT6R7JZ Strong Biomarker [247]
HGFAC TTD96RW Strong Altered Expression [287]
HLA-G TTLKFB3 Strong Biomarker [288]
HNF4A TT2F3CD Strong Posttranslational Modification [289]
HOXB13 TTZ6I58 Strong Altered Expression [290]
HPN TT25MVL Strong Altered Expression [291]
HSD11B2 TT9H85R Strong Biomarker [292]
HSPA9 TTMTPG3 Strong Biomarker [228]
HSPD1 TT9HL5R Strong Biomarker [228]
IAPP TTHN8EM Strong Altered Expression [167]
IDO1 TTZJYKH Strong Biomarker [293]
IFNAR2 TTMQB37 Strong Altered Expression [294]
IGF1R TTQFBMY Strong Biomarker [295]
IGFBP2 TTU4QSN Strong Altered Expression [296]
IGFBP5 TTDWEA8 Strong Biomarker [297]
IGFBP6 TTLAYV8 Strong Altered Expression [297]
IL17D TTC5LTG Strong Biomarker [298]
IL2 TTF89GD Strong Biomarker [299]
IL24 TT1EPXZ Strong Biomarker [300]
IL4R TTDWHC3 Strong Biomarker [301]
ILK TT7ALZG Strong Biomarker [302]
INHBA TTVB30D Strong Biomarker [303]
INSR TTCBFJO Strong Altered Expression [304]
IRF8 TTHUBNK Strong Altered Expression [305]
ITGA1 TTPERWV Strong Altered Expression [306]
ITGA5 TTHIZP9 Strong Altered Expression [307]
ITGAV TTT1R2L Strong Altered Expression [307]
ITK TT3C80U Strong Biomarker [308]
ITPR1 TT5HWAT Strong Biomarker [309]
ITPR2 TTK9OV3 Strong Genetic Variation [310]
JUP TTREN0G Strong Biomarker [311]
KCNMA1 TTE87WJ Strong Biomarker [312]
KDM3A TTKXS4A Strong Biomarker [313]
KDM4C TTV8CRH Strong Genetic Variation [314]
KDM6B TTDIJUQ Strong Biomarker [315]
KHDRBS1 TTAT6C7 Strong Altered Expression [316]
KHK TTPAFR9 Strong Altered Expression [317]
KIR2DL2 TTU0P73 Strong Altered Expression [318]
KIR2DL3 TTEX3SI Strong Altered Expression [318]
KIR2DS2 TTV3CFI Strong Altered Expression [318]
KISS1 TTU2O6T Strong Biomarker [319]
KISS1R TT3KBZY Strong Biomarker [320]
KITLG TTDJ51N Strong Altered Expression [321]
KLK1 TT5T3P6 Strong Biomarker [322]
KLK2 TTJLNAW Strong Biomarker [323]
KLK3 TTS78AZ Strong Altered Expression [324]
KLK4 TT4319X Strong Altered Expression [325]
KLK7 TTE6GTB Strong Altered Expression [326]
KLRC1 TTC4IMS Strong Biomarker [327]
L1CAM TTC9D3K Strong Altered Expression [194]
LAG3 TTNVXAW Strong Biomarker [328]
LAPTM4B TTEJQT0 Strong Biomarker [329]
LDHA TTW76JE Strong Altered Expression [330]
LGALS3 TTFPQV7 Strong Altered Expression [331]
LIFR TTID542 Strong Biomarker [332]
LILRB1 TTC0QRJ Strong Altered Expression [333]
LNPEP TTY2KP7 Strong Altered Expression [334]
LRRK2 TTK0FEA Strong Biomarker [231]
M6PR TT95ICL Strong Biomarker [312]
MAD1L1 TTNE9U7 Strong Biomarker [335]
MAGEA2 TTOZT28 Strong Genetic Variation [336]
MAGEA4 TT9EQUY Strong Altered Expression [337]
MAGEA6 TTJIWMO Strong Altered Expression [338]
MANF TT56RYE Strong Genetic Variation [339]
MAOB TTGP7BY Strong Biomarker [340]
MAP2K1 TTIDAPM Strong Altered Expression [341]
MAP3K5 TTOQCD8 Strong Biomarker [342]
MAP3K8 TTGECUM Strong Biomarker [343]
MAP3K9 TTUNSIX Strong Altered Expression [344]
MAPKAP1 TTWDKCL Strong Altered Expression [345]
MARK2 TTAJ45Y Strong Genetic Variation [346]
MAT2A TTSMPXQ Strong Biomarker [347]
MCL1 TTL53M6 Strong Altered Expression [348]
MDM2 TT9TE0O Strong Biomarker [349]
MKI67 TTB4UNG Strong Altered Expression [350]
MME TT5TKPM Strong Biomarker [207]
MMP11 TTZW4MV Strong Biomarker [351]
MMP16 TTNP4CU Strong Altered Expression [352]
MST1R TTBQ3OC Strong Altered Expression [353]
MTDH TTH6SA5 Strong Altered Expression [354]
MTNR1A TT0WAIE Strong Altered Expression [355]
MUC16 TTC1PS3 Strong Altered Expression [356]
MUC17 TTVO0JU Strong Altered Expression [357]
MYC TTNQ5ZP Strong Biomarker [69]
NDUFA13 TTRU1NG Strong Altered Expression [358]
NEDD8 TTNDC4K Strong Altered Expression [359]
NEK1 TTO5QT2 Strong Altered Expression [360]
NELL1 TT7H4BF Strong Posttranslational Modification [361]
NES TTHZ752 Strong Biomarker [362]
NF2 TTZIK7P Strong Biomarker [265]
NFKB2 TTKLNRV Strong Altered Expression [145]
NR1H2 TTXA6PH Strong Genetic Variation [363]
NR4A1 TTMXE2Q Strong Biomarker [364]
NRAS TTW2R9X Strong Genetic Variation [365]
NRP1 TTIPJCB Strong Biomarker [366]
NRP2 TTRXUVC Strong Biomarker [367]
OGG1 TTRU01G Strong Genetic Variation [368]
P2RY1 TTA93TL Strong Biomarker [369]
PCNA TTLG1PD Strong Altered Expression [370]
PCSK7 TTD30LY Strong Biomarker [371]
PDCD1 TTNBFWK Strong Biomarker [372]
PDCD1LG2 TTW14O3 Strong Biomarker [373]
PDGFA TTSM78N Strong Altered Expression [169]
PDGFC TTOABM9 Strong Biomarker [374]
PDGFD TTSN0GA Strong Altered Expression [375]
PDGFRB TTI7421 Strong Biomarker [376]
PDZK1 TTDTBLM Strong Biomarker [377]
PEBP1 TT1BGU8 Strong Biomarker [378]
PECAM1 TT4EZB2 Strong Altered Expression [379]
PGRMC1 TTY3LAZ Strong Biomarker [179]
PHGDH TT8DRCK Strong Biomarker [380]
PIK3CA TTEUNMR Strong Genetic Variation [381]
PIK3CB TT9H4P3 Strong Genetic Variation [381]
PINX1 TT4FJ3A Strong Biomarker [382]
PLA2R1 TTHKW7D Strong Biomarker [383]
PLK1 TTH4IP0 Strong Altered Expression [384]
PLOD2 TT8MEUD Strong Biomarker [385]
POMC TT21AKM Strong Altered Expression [386]
PPAT TTZFTY4 Strong Biomarker [387]
PRAME TTPH7T0 Strong Biomarker [388]
PRKCH TTONI0R Strong Altered Expression [389]
PRKCZ TTBSN0L Strong Altered Expression [390]
PRSS8 TTT4N0Q Strong Biomarker [391]
PSMB6 TT8EPLT Strong Altered Expression [243]
PSMB8 TTEAD9J Strong Altered Expression [392]
PSMB9 TTOUSTQ Strong Genetic Variation [392]
PTBP1 TTWMX0U Strong Biomarker [393]
PTGER4 TT79WV3 Strong Biomarker [394]
PTGS1 TT8NGED Strong Altered Expression [395]
PTGS2 TTVKILB Strong Altered Expression [396]
PTH1R TTFPD47 Strong Altered Expression [397]
PTK2 TTON5IT Strong Altered Expression [398]
PTK2B TTTEFBV Strong Biomarker [399]
PTPRZ1 TT4SEA8 Strong Altered Expression [400]
PYY TTVFJLX Strong Genetic Variation [401]
QPCT TTJ7YTV Strong Posttranslational Modification [402]
RAB22A TTAJ746 Strong Biomarker [403]
RACK1 TTJ10AL Strong Biomarker [404]
RALBP1 TTVSRUA Strong Biomarker [405]
RARB TTISP28 Strong Altered Expression [406]
RET TT4DXQT Strong Biomarker [127]
RHO TTH0KSX Strong Biomarker [407]
RHOB TT6LPFO Strong Biomarker [408]
RICTOR TT143WL Strong Altered Expression [409]
RNF34 TTEWDK1 Strong Biomarker [410]
RNPEP TTD74YX Strong Altered Expression [411]
ROBO1 TTND1YP Strong Genetic Variation [412]
ROCK1 TTZN7RP Strong Biomarker [413]
ROR2 TTUDPCI Strong Altered Expression [414]
RPS6KA6 TT3KYWB Strong Biomarker [415]
RSF1 TTMP86V Strong Altered Expression [416]
RXRG TTH029C Strong Altered Expression [417]
RYR1 TTU5CIX Strong Biomarker [231]
S100A9 TT0TMQG Strong Altered Expression [418]
SELE TT1PL7M Strong Altered Expression [419]
SF3B1 TTL2WUI Strong Genetic Variation [365]
SLC12A3 TTP362L Strong Biomarker [420]
SLC15A1 TT5LF3C Strong Biomarker [421]
SLC16A3 TTG6VD5 Strong Altered Expression [330]
SLC22A2 TT0XOJN Strong Biomarker [422]
SLC2A1 TT79TKF Strong Altered Expression [423]
SLC2A4 TTP6MT5 Strong Biomarker [423]
SLC34A2 TTQPZTM Strong Altered Expression [424]
SLC3A2 TT5CZSM Strong Biomarker [425]
SLC8A1 TTCF82X Strong Altered Expression [426]
SMYD2 TT7YJFO Strong Biomarker [427]
SOCS3 TTI0ME6 Strong Altered Expression [428]
SORD TTLSRBZ Strong Genetic Variation [429]
SRC TT6PKBN Strong Biomarker [123]
ST14 TTPRO7W Strong Altered Expression [430]
SULF2 TTLQTHB Strong Biomarker [431]
SYVN1 TT8XKYM Strong Genetic Variation [432]
TAGLN2 TTP6BIJ Strong Biomarker [228]
TEC TT1ZV49 Strong Biomarker [433]
TEK TT9VGXW Strong Biomarker [434]
TEP1 TTQGAVX Strong Altered Expression [435]
TERF1 TT1Y6J2 Strong Altered Expression [436]
TERF2 TT5XSLT Strong Altered Expression [436]
TFAP2A TTDY4BS Strong Biomarker [437]
TGFA TTTLQFR Strong Biomarker [438]
TIAM1 TTNU6I5 Strong Biomarker [439]
TIE1 TTT4236 Strong Biomarker [440]
TMSB4X TTMVAIU Strong Altered Expression [441]
TNFRSF10A TT5WLRX Strong Biomarker [442]
TNFRSF10B TTW20TU Strong Biomarker [443]
TNFRSF12A TTKPS7V Strong Altered Expression [444]
TNFSF12 TTBTDM1 Strong Altered Expression [444]
TNFSF15 TTEST6I Strong Altered Expression [445]
TPBG TT70MLA Strong Altered Expression [446]
TPT1 TT3PTB6 Strong Altered Expression [447]
TREM2 TTQRMSJ Strong Altered Expression [448]
TRIM59 TT613U4 Strong Biomarker [449]
TRIP10 TTKHTGE Strong Biomarker [450]
TRPC4 TTX0H5W Strong Biomarker [451]
TXNIP TTTLDZK Strong Biomarker [452]
UBE2T TT0A1R8 Strong Altered Expression [453]
UCHL1 TTX9IFP Strong Altered Expression [454]
USP1 TTG9MT5 Strong Posttranslational Modification [454]
VEGFB TTPJQHE Strong Altered Expression [455]
VEGFC TT0QUFV Strong Biomarker [456]
VHL TTEMWSD Strong Autosomal dominant [51]
VTCN1 TTCK85E Strong Biomarker [457]
WNT7A TT8NARC Strong Biomarker [458]
XIAP TTK3WBU Strong Altered Expression [459]
ZEB2 TTT2WK4 Strong Genetic Variation [150]
ACHE TT1RS9F Definitive Altered Expression [460]
ATM TTKBM7V Definitive Genetic Variation [461]
BCHE TT3MSAO Definitive Altered Expression [460]
CCK TT90CMU Definitive Biomarker [402]
CLU TTRL76H Definitive Biomarker [462]
COL18A1 TT63DI9 Definitive Biomarker [463]
CUBN TT9YLCR Definitive Altered Expression [464]
GJB1 TTSJIRP Definitive Biomarker [465]
NUF2 TTIXBFP Definitive Altered Expression [466]
PBRM1 TTH8ZRL Definitive Biomarker [467]
TGM2 TT2F4OL Definitive Biomarker [468]
------------------------------------------------------------------------------------
⏷ Show the Full List of 469 DTT(s)
This Disease Is Related to 12 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCC6 DT582KR Strong Altered Expression [469]
ABCD1 DTKM9DZ Strong Altered Expression [470]
SLC25A3 DTCRIWV Strong Genetic Variation [471]
SLC25A5 DTL1TRY Strong Biomarker [472]
SLC2A2 DTUJPOL Strong Altered Expression [473]
SLC2A3 DT9SQ3L Strong Altered Expression [474]
SLC39A10 DTK02RZ Strong Biomarker [475]
SLC39A11 DTEOAND Strong Genetic Variation [476]
SLC4A4 DTWDEIL Strong Altered Expression [477]
SLC50A1 DTI9CQU Strong Biomarker [275]
SLC5A3 DT8ACN1 Strong Biomarker [265]
SLCO6A1 DTIFXNS Strong Genetic Variation [342]
------------------------------------------------------------------------------------
⏷ Show the Full List of 12 DTP(s)
This Disease Is Related to 18 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
ACSS2 DEE76VW Limited Biomarker [478]
AKR1A1 DED2FW3 Limited Genetic Variation [479]
ALDH1A1 DE2JP1Y Limited Biomarker [480]
CYP1A1 DE6OQ3W moderate Biomarker [481]
LDHC DEQG7F9 moderate Biomarker [482]
UBASH3B DE10BJ5 moderate Biomarker [483]
AGMAT DEG5L6E Strong Biomarker [484]
APRT DE2MV1R Strong Biomarker [338]
CYP2R1 DEBIHM3 Strong Biomarker [236]
GPT DER5HFI Strong Biomarker [485]
GSTO2 DEHMPZR Strong Genetic Variation [286]
HIF1AN DEY1CBW Strong Altered Expression [486]
MT1A DE5ME8A Strong Altered Expression [487]
NAT1 DE7OAB3 Strong Genetic Variation [488]
NAT10 DEZV4AP Strong Biomarker [176]
NNMT DECVGJ3 Strong Altered Expression [489]
PARK7 DEPOVCH Strong Biomarker [490]
GSTT1 DE3PKUG Definitive Genetic Variation [76]
------------------------------------------------------------------------------------
⏷ Show the Full List of 18 DME(s)

References

1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5659).
4 ClinicalTrials.gov (NCT04586231) A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011). U.S. National Institutes of Health.
5 ClinicalTrials.gov (NCT01895972) A Study Evaluating the Long-Term Safety of Latanoprostene Bunod Ophthalmic Solution 0.024%, in Japanese Subjects With Open-Angle Glaucoma or Ocular Hypertension. U.S.National Institutes of Health.
6 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
7 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5889).
8 Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
9 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026173)
10 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7006).
11 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8257).
12 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5711).
13 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5892).
14 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services
15 FDA Accepts BPL's Amended BLA Submission for Coagadex (Coagulation Factor X, Human). BPL Bio Products Laboratory USA, Inc.
16 ClinicalTrials.gov (NCT03592472) A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV). U.S. National Institutes of Health.
17 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
18 ClinicalTrials.gov (NCT01265901) IMA901 in Patients Receiving Sunitinib for Advanced/Metastatic Renal Cell Carcinoma. U.S. National Institutes of Health.
19 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
20 ClinicalTrials.gov (NCT01223027) Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma. U.S. National Institutes of Health.
21 ClinicalTrials.gov (NCT00467025) AMG 386, 20060159 Phase 2, RCC 1st Line in Combination With Sorafenib. U.S. National Institutes of Health.
22 ClinicalTrials.gov (NCT00033904) Survival Study Of Oncophage vs. Observation In Patients With Kidney Cancer. U.S. National Institutes of Health.
23 ClinicalTrials.gov (NCT00735332) Efficacy Study of TLN-232 in Patients With Recurring Metastatic Melanoma. U.S. National Institutes of Health.
24 ClinicalTrials.gov (NCT01482949) A Rollover Protocol for Subjects Previously Treated With AGS-003. U.S. National Institutes of Health.
25 ClinicalTrials.gov (NCT00131651) ATN-161 in Advanced Renal Cell Cancer. U.S. National Institutes of Health.
26 Clinical pipeline report, company report or official report of Dartmouth-Hitchcock Medical Center.
27 ClinicalTrials.gov (NCT04203901) A Phase 2b Randomized Trial of Autologous Dendritic Cell Immunotherapy (CMN-001) Plus Standard Treatment of Advanced Renal Cell Carcinoma. U.S.National Institutes of Health.
28 ClinicalTrials.gov (NCT04388852) DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers. U.S. National Institutes of Health.
29 ClinicalTrials.gov (NCT01511055) Intra-op Detection of Occult Ovarian Carcinoma Using a Folate-Alpha Receptor Specific Fluorescent Ligand. U.S. National Institutes of Health.
30 ClinicalTrials.gov (NCT00717587) Sunitinib Before and After Surgery in Treating Patients With Stage IV Kidney Cancer. U.S. National Institutes of Health.
31 Clinical pipeline report, company report or official report of Immunservice GmbH.
32 Clinical pipeline report, company report or official report of Idera Pharmaceuticals (2011).
33 ClinicalTrials.gov (NCT00095628) SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer. U.S. National Institutes of Health.
34 Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin. Mol Cancer Ther. 2011 Aug;10(8):1394-406.
35 Rethinking Immunotherapy for Brain Tumors. Michael D. Becker, MDB Communications LLC. February 22, 2012.
36 Clinical pipeline report, company report or official report of TVAX Biomedical.
37 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5679).
38 ClinicalTrials.gov (NCT03638206) Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies
39 ClinicalTrials.gov (NCT03393936) Safety and Efficacy of CCT301 CAR-T in Adult Subjects With Recurrent or Refractory Stage IV Renal Cell Carcinoma
40 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020218)
41 ClinicalTrials.gov (NCT00816686) A Phase 1 Study of the Safety and Pharmacokinetics of AGS-16M18 in Subjects With Advanced Renal Cell Cancer. U.S. National Institutes of Health.
42 ClinicalTrials.gov (NCT01497821) AMG 172 First in Human Study in Patients With Kidney Cancer. U.S. National Institutes of Health.
43 ClinicalTrials.gov (NCT02830724) Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
44 ClinicalTrials.gov (NCT04169711) Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma. U.S. National Institutes of Health.
45 ClinicalTrials.gov (NCT00004890) Biomed 101 and Interleukin-2 in Treating Patients With Kidney Cancer. U.S. National Institutes of Health.
46 Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study. Gene Ther. 2011 Apr;18(4):354-63.
47 Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
48 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020056)
49 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020387)
50 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
51 The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.
52 Down-regulation of miR-210-3p encourages chemotherapy resistance of renal cell carcinoma via modulating ABCC1.Cell Biosci. 2018 Feb 7;8:9. doi: 10.1186/s13578-018-0209-3. eCollection 2018.
53 A novel miR-203-DNMT3b-ABCG2 regulatory pathway predisposing colorectal cancer development.Mol Carcinog. 2017 Feb;56(2):464-477. doi: 10.1002/mc.22508. Epub 2016 Jun 10.
54 The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma.Carcinogenesis. 2011 Nov;32(11):1713-23. doi: 10.1093/carcin/bgr195. Epub 2011 Aug 30.
55 Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers. Nat Commun. 2018 Sep 26;9(1):3931.
56 Do clear cell papillary renal cell carcinomas have malignant potential? Diolombi ML, Cheng L, Argani P, Epstein JI.Am J Surg Pathol. December 2015;39(12):1621-1634.Urol Oncol. 2017 Jun;35(6):451-452. doi: 10.1016/j.urolonc.2017.03.020. Epub 2017 Apr 14.
57 Apelin and apelin receptor expression in renal cell carcinoma.Br J Cancer. 2019 Mar;120(6):633-639. doi: 10.1038/s41416-019-0396-7. Epub 2019 Feb 20.
58 Bexarotene - a novel modulator of AURKA and the primary cilium in VHL-deficient cells.J Cell Sci. 2018 Dec 14;131(24):jcs219923. doi: 10.1242/jcs.219923.
59 MALAT1 accelerates the development and progression of renal cell carcinoma by decreasing the expression of miR-203 and promoting the expression of BIRC5.Cell Prolif. 2019 Sep;52(5):e12640. doi: 10.1111/cpr.12640. Epub 2019 Jun 27.
60 Down-Regulation of Circular RNA_000926 Attenuates Renal Cell Carcinoma Progression through miRNA-411-Dependent CDH2 Inhibition.Am J Pathol. 2019 Dec;189(12):2469-2486. doi: 10.1016/j.ajpath.2019.06.016. Epub 2019 Aug 30.
61 sE-cadherin is upregulated in serum of patients with renal cell carcinoma and promotes tumor cell dissemination in vitro.Urol Oncol. 2019 Jun;37(6):355.e1-355.e9. doi: 10.1016/j.urolonc.2019.03.001. Epub 2019 Apr 18.
62 Cadherin-6 gene expression in conventional renal cell carcinoma: a useful marker to detect circulating tumor cells.Anticancer Res. 2005 Jan-Feb;25(1A):377-81.
63 TMIGD1 acts as a tumor suppressor through regulation of p21Cip1/p27Kip1 in renal cancer.Oncotarget. 2017 Dec 26;9(11):9672-9684. doi: 10.18632/oncotarget.23822. eCollection 2018 Feb 9.
64 c-FLIP and CD95 signaling are essential for survival of renal cell carcinoma.Cell Death Dis. 2019 May 16;10(6):384. doi: 10.1038/s41419-019-1609-y.
65 Identification of potential core genes in metastatic renal cell carcinoma using bioinformatics analysis.Am J Transl Res. 2019 Nov 15;11(11):6812-6825. eCollection 2019.
66 Up-regulation of 5-lipoxygenase by inhibition of cathepsin G enhances TRAIL-induced apoptosis through down-regulation of survivin.Oncotarget. 2017 Nov 20;8(63):106672-106684. doi: 10.18632/oncotarget.22508. eCollection 2017 Dec 5.
67 Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways.Clin Cancer Res. 2009 Sep 15;15(18):5678-87. doi: 10.1158/1078-0432.CCR-09-0558.
68 Are primary renal cell carcinoma and metastases of renal cell carcinoma the same cancer?.Urol Oncol. 2016 May;34(5):215-20. doi: 10.1016/j.urolonc.2015.12.013. Epub 2016 Feb 2.
69 Molecular profiling of transcription factors pinpoints MYC-estrogen related receptor -regulatory factor X5 panel for characterizing the immune microenvironment and predicting the efficacy of immune checkpoint inhibitors in renal cell carcinoma.Oncol Lett. 2019 Aug;18(2):1895-1903. doi: 10.3892/ol.2019.10523. Epub 2019 Jun 24.
70 Integrative Epigenetic and Gene Expression Analysis of Renal Tumor Progression to Metastasis.Mol Cancer Res. 2019 Jan;17(1):84-96. doi: 10.1158/1541-7786.MCR-17-0636. Epub 2018 Aug 21.
71 Fbxw7 regulates renal cell carcinoma migration and invasion via suppression of the epithelial-mesenchymal transition.Oncol Lett. 2018 Mar;15(3):3694-3702. doi: 10.3892/ol.2018.7744. Epub 2018 Jan 8.
72 Mutational activation of FGFR3: no involvement in the development of renal cell carcinoma.J Cancer Res Clin Oncol. 2012 Feb;138(2):359-61. doi: 10.1007/s00432-011-1130-x. Epub 2011 Dec 28.
73 FK506 Binding Protein 10 Is Overexpressed and Promotes Renal Cell Carcinoma.Urol Int. 2017;98(2):169-176. doi: 10.1159/000448338. Epub 2016 Sep 8.
74 Homeodomain interacting protein kinase-2 phosphorylates FOXM1 and promotes FOXM1-mediated tumor growth in renal cell carcinoma.J Cell Biochem. 2019 Jun;120(6):10391-10401. doi: 10.1002/jcb.28323. Epub 2019 Jan 4.
75 Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.Cancer Immunol Immunother. 2017 Jan;66(1):17-24. doi: 10.1007/s00262-016-1915-5. Epub 2016 Oct 18.
76 A systematic review and meta-analyses of the relationship between glutathione S-transferase gene polymorphisms and renal cell carcinoma susceptibility.BMC Med Genet. 2018 Jun 8;19(1):98. doi: 10.1186/s12881-018-0620-y.
77 Significant induction of apoptosis in renal cell carcinoma cells transfected with cationic multilamellar liposomes containing the human interferon- gene through activation of the intracellular type 1 interferon signal pathway.Int J Oncol. 2012 May;40(5):1441-6. doi: 10.3892/ijo.2012.1377. Epub 2012 Feb 16.
78 Circulating and tissue IMP3 levels are correlated with poor survival in renal cell carcinoma.Int J Cancer. 2019 Jul 15;145(2):531-539. doi: 10.1002/ijc.32124. Epub 2019 Jan 31.
79 NEAT1-TFE3 and KAT6A-TFE3 renal cell carcinomas, new members of MiT family translocation renal cell carcinoma.Mod Pathol. 2019 May;32(5):710-716. doi: 10.1038/s41379-018-0191-7. Epub 2019 Jan 8.
80 Epigenetic modifiers: activities in renal cell carcinoma.Nat Rev Urol. 2018 Oct;15(10):599-614. doi: 10.1038/s41585-018-0052-7.
81 KIF20B promotes the progression of clear cell renal cell carcinoma by stimulating cell proliferation.J Cell Physiol. 2019 Sep;234(9):16517-16525. doi: 10.1002/jcp.28322. Epub 2019 Feb 25.
82 Leukocyteassociated immunoglobulinlike receptor1 promotes tumorigenesis in RCC.Oncol Rep. 2019 Feb;41(2):1293-1303. doi: 10.3892/or.2018.6875. Epub 2018 Nov 20.
83 Silencing of lysyl oxidaselike 2 inhibits the migration, invasion and epithelialtomesenchymal transition of renal cell carcinoma cells through the Src/FAK signaling pathway.Int J Oncol. 2019 May;54(5):1676-1690. doi: 10.3892/ijo.2019.4726. Epub 2019 Feb 27.
84 Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation.J Biol Chem. 2019 Jun 7;294(23):9029-9036. doi: 10.1074/jbc.AC119.007466. Epub 2019 Apr 24.
85 Design, synthesis and biological evaluation of 4-aniline-thieno[2,3-d]pyrimidine derivatives as MNK1 inhibitors against renal cell carcinoma and nasopharyngeal carcinoma.Bioorg Med Chem. 2019 Jun 1;27(11):2268-2279. doi: 10.1016/j.bmc.2019.04.022. Epub 2019 Apr 17.
86 Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.Int J Cancer. 2020 Feb 15;146(4):1052-1063. doi: 10.1002/ijc.32543. Epub 2019 Jul 16.
87 The Silencing of CCND2 by Promoter Aberrant Methylation in Renal Cell Cancer and Analysis of the Correlation between CCND2 Methylation Status and Clinical Features.PLoS One. 2016 Sep 1;11(9):e0161859. doi: 10.1371/journal.pone.0161859. eCollection 2016.
88 Overexpression of NEDD9 in renal cell carcinoma is associated with tumor migration and invasion.Oncol Lett. 2017 Dec;14(6):8021-8027. doi: 10.3892/ol.2017.7231. Epub 2017 Oct 20.
89 MicroRNA-96 is a potential tumor repressor by inhibiting NPTX2 in renal cell carcinoma.J Cell Biochem. 2020 Feb;121(2):1504-1513. doi: 10.1002/jcb.29385. Epub 2019 Sep 9.
90 NT5E inhibition suppresses the growth of sunitinib-resistant cells and EMT course and AKT/GSK-3 signaling pathway in renal cell cancer.IUBMB Life. 2019 Jan;71(1):113-124. doi: 10.1002/iub.1942. Epub 2018 Oct 3.
91 Low expression of PDK1 inhibits renal cell carcinoma cell proliferation, migration, invasion and epithelial mesenchymal transition through inhibition of the PI3K-PDK1-Akt pathway.Cell Signal. 2019 Apr;56:1-14. doi: 10.1016/j.cellsig.2018.11.016. Epub 2018 Nov 20.
92 Activation of AMPK by metformin promotes renal cancer cell proliferation under glucose deprivation through its interaction with PKM2.Int J Biol Sci. 2019 Jan 1;15(3):617-627. doi: 10.7150/ijbs.29689. eCollection 2019.
93 Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma.EBioMedicine. 2019 Jan;39:255-264. doi: 10.1016/j.ebiom.2018.12.011. Epub 2018 Dec 14.
94 RBCK1 promotes p53 degradation via ubiquitination in renal cell carcinoma.Cell Death Dis. 2019 Mar 15;10(4):254. doi: 10.1038/s41419-019-1488-2.
95 The cancer-retina antigen recoverin as a potential biomarker for renal tumors.Tumour Biol. 2016 Jul;37(7):9899-907. doi: 10.1007/s13277-016-4885-5. Epub 2016 Jan 26.
96 Inhibition of Sphingosine Phosphate Receptor 1 Signaling Enhances the Efficacy of VEGF Receptor Inhibition.Mol Cancer Ther. 2019 Apr;18(4):856-867. doi: 10.1158/1535-7163.MCT-18-0548. Epub 2019 Feb 20.
97 Wnt antagonist gene polymorphisms and renal cancer.Cancer. 2009 Oct 1;115(19):4488-503. doi: 10.1002/cncr.24491.
98 Immunohistochemical expressionof sodium-dependent glucose transporter - 2 (SGLT-2) in clear cell renal carcinoma: possible prognostic implications.Int Braz J Urol. 2019 Jan-Feb;45(1):169-178. doi: 10.1590/S1677-5538.IBJU.2018.0271.
99 Suppression of Tescalcin inhibits growth and metastasis in renal cell carcinoma via downregulating NHE1 and NF-kB signaling.Exp Mol Pathol. 2019 Apr;107:110-117. doi: 10.1016/j.yexmp.2018.12.004. Epub 2018 Dec 27.
100 Long non-coding RNA GAS5 sensitizes renal cell carcinoma to sorafenib via miR-21/SOX5 pathway.Cell Cycle. 2019 Feb;18(3):257-263. doi: 10.1080/15384101.2018.1475826. Epub 2019 Jan 29.
101 Knockdown of Serine-Arginine Protein Kinase 1 Inhibits the Growth and Migration in Renal Cell Carcinoma Cells.Oncol Res. 2017 Mar 13;25(3):389-395. doi: 10.3727/096504016X14743324568129. Epub 2016 Sep 22.
102 The significance of TRIP11 and T3 signalling pathway in renal cancer progression and survival of patients.Endokrynol Pol. 2017;68(6):631-641. doi: 10.5603/EP.a2017.0052. Epub 2017 Oct 12.
103 Molecular cloning and immunogenicity of renal cell carcinoma-associated antigen G250.Int J Cancer. 2000 Mar 15;85(6):865-70. doi: 10.1002/(sici)1097-0215(20000315)85:6<865::aid-ijc21>3.0.co;2-q.
104 WNK1 promotes renal tumor progression by activating TRPC6-NFAT pathway.FASEB J. 2019 Jul;33(7):8588-8599. doi: 10.1096/fj.201802019RR. Epub 2019 Apr 25.
105 siRNA against TSG101 reduces proliferation and induces G0/G1 arrest in renal cell carcinoma - involvement of c-myc, cyclin E1, and CDK2.Cell Mol Biol Lett. 2019 Jan 15;24:7. doi: 10.1186/s11658-018-0124-y. eCollection 2019.
106 Increased UCP1 expression in the perirenal adipose tissue of patients with renal cell carcinoma.Oncol Rep. 2019 Nov;42(5):1972-1980. doi: 10.3892/or.2019.7306. Epub 2019 Sep 10.
107 Genomic and proteomic approaches to renal cell carcinoma.J Nephrol. 2011 Mar-Apr;24(2):155-64. doi: 10.5301/jn.2010.90.
108 Development of a novel interferon-2b gene construct with a repetitive hypoxia-inducible factor binding site and its suppressive effects on human renal cell carcinoma cell lines in vitro.Int J Clin Oncol. 2014;19(3):497-504. doi: 10.1007/s10147-013-0568-z. Epub 2013 Jun 6.
109 p21-activated kinase 1 determines stem-like phenotype and sunitinib resistance via NF-B/IL-6 activation in renal cell carcinoma.Cell Death Dis. 2015 Feb 12;6(2):e1637. doi: 10.1038/cddis.2015.2.
110 Superoxide dismutase 2 expression can predict prognosis of renal cell carcinoma patients.Cancer Biomark. 2018;22(4):755-761. doi: 10.3233/CBM-181308.
111 Overexpression of ATP citrate lyase in renal cell carcinoma tissues and its effect on the human renal carcinoma cells in vitro.Oncol Lett. 2018 May;15(5):6967-6974. doi: 10.3892/ol.2018.8211. Epub 2018 Mar 8.
112 A phase 2, randomized trial evaluating the combination of dalantercept plus axitinib in patients with advanced clear cell renal cell carcinoma.Cancer. 2019 Jul 15;125(14):2400-2408. doi: 10.1002/cncr.32061. Epub 2019 Apr 5.
113 Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer.Cancer Discov. 2020 Jan;10(1):40-53. doi: 10.1158/2159-8290.CD-19-0980. Epub 2019 Nov 15.
114 Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.Cell Metab. 2018 Jun 5;27(6):1263-1280.e6. doi: 10.1016/j.cmet.2018.04.009. Epub 2018 May 10.
115 Arrestin2 Mediates Renal Cell Carcinoma Tumor Growth.Sci Rep. 2018 Mar 20;8(1):4879. doi: 10.1038/s41598-018-23212-w.
116 Discovery and validation of methylated-differentially expressed genes in Helicobacter pylori-induced gastric cancer.Cancer Gene Ther. 2020 Jun;27(6):473-485. doi: 10.1038/s41417-019-0125-7. Epub 2019 Jul 16.
117 Sorafenib induces renal cell carcinoma apoptosis via upregulating activating transcription factor 4.Pharmazie. 2018 Mar 5;73(3):156-160. doi: 10.1691/ph.2018.7855.
118 Decreased miR-200a-3p is a key regulator of renal carcinoma growth and migration by directly targeting CBL.J Cell Biochem. 2018 Dec;119(12):9974-9985. doi: 10.1002/jcb.27326. Epub 2018 Sep 1.
119 6-Gingerol induces cell-cycle G1-phase arrest through AKT-GSK 3-cyclin D1 pathway in renal-cell carcinoma.Cancer Chemother Pharmacol. 2020 Feb;85(2):379-390. doi: 10.1007/s00280-019-03999-9. Epub 2019 Dec 12.
120 LINC01510 suppresses cell proliferation and invasion by inhibiting Wnt/-catenin signaling in renal cell carcinoma.Biochem Biophys Res Commun. 2018 Oct 20;505(1):7-12. doi: 10.1016/j.bbrc.2018.08.167. Epub 2018 Sep 14.
121 REG deficiency suppresses tumor progression via stabilizing CK1 in renal cell carcinoma.Cell Death Dis. 2018 May 24;9(6):627. doi: 10.1038/s41419-018-0646-2.
122 IL-8 and CXCR1 expression is associated with cancer stem cell-like properties of clear cell renal cancer.J Pathol. 2019 Jul;248(3):377-389. doi: 10.1002/path.5267. Epub 2019 Apr 11.
123 Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer.Int J Cancer. 2018 Sep 1;143(5):1162-1175. doi: 10.1002/ijc.31400. Epub 2018 Apr 16.
124 Orphan nuclear receptor COUP-TFII is an oncogenic gene in renal cell carcinoma.Clin Transl Oncol. 2020 May;22(5):772-781. doi: 10.1007/s12094-019-02190-z. Epub 2019 Jul 31.
125 High expression of F2RL3 correlates with aggressive features and poor survival in clear cell renal cell carcinoma.J Cancer. 2018 Sep 8;9(18):3400-3406. doi: 10.7150/jca.23923. eCollection 2018.
126 miR-1-3p suppresses the epithelial-mesenchymal transition property in renal cell cancer by downregulating Fibronectin 1.Cancer Manag Res. 2019 Jun 21;11:5573-5587. doi: 10.2147/CMAR.S200707. eCollection 2019.
127 TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease.Mol Cancer Res. 2019 Aug;17(8):1613-1626. doi: 10.1158/1541-7786.MCR-18-1235. Epub 2019 May 1.
128 microRNA-302c-3p inhibits renal cell carcinoma cell proliferation by targeting Grb2-associated binding 2 (Gab2).Oncotarget. 2017 Apr 18;8(16):26334-26343. doi: 10.18632/oncotarget.15463.
129 Clinical significance of glutamate metabotropic receptors in renal cell carcinoma risk and survival.Cancer Med. 2018 Dec;7(12):6104-6111. doi: 10.1002/cam4.1901. Epub 2018 Nov 28.
130 Loss of function of the tissue specific transcription factor HNF1 alpha in renal cell carcinoma and clinical prognosis.Anticancer Res. 1999 May-Jun;19(3A):2105-10.
131 Epigenetic inactivation of HOXA11, a novel functional tumor suppressor for renal cell carcinoma, is associated with RCC TNM classification.Oncotarget. 2017 Mar 28;8(13):21861-21870. doi: 10.18632/oncotarget.15668.
132 SFPQ/PSF-TFE3 renal cell carcinoma: a clinicopathologic study emphasizing extended morphology and reviewing the differences between SFPQ-TFE3 RCC and the corresponding mesenchymal neoplasm despite an identical gene fusion.Hum Pathol. 2017 May;63:190-200. doi: 10.1016/j.humpath.2017.02.022. Epub 2017 Mar 14.
133 Interferon-alpha enhances CD317 expression and the antitumor activity of anti-CD317 monoclonal antibody in renal cell carcinoma xenograft models.Cancer Sci. 2008 Dec;99(12):2461-6. doi: 10.1111/j.1349-7006.2008.00968.x. Epub 2008 Nov 20.
134 The Role of YB1 in Renal Cell Carcinoma Cell Adhesion.Int J Med Sci. 2018 Aug 6;15(12):1304-1311. doi: 10.7150/ijms.25580. eCollection 2018.
135 Reduction in H3K4me patterns due to aberrant expression of methyltransferases and demethylases in renal cell carcinoma: prognostic and therapeutic implications.Sci Rep. 2019 Jun 3;9(1):8189. doi: 10.1038/s41598-019-44733-y.
136 Downregulation of Keap1 contributes to poor prognosis and Axitinib resistance of renal cell carcinoma via upregulation of Nrf2 expression.Int J Mol Med. 2019 May;43(5):2044-2054. doi: 10.3892/ijmm.2019.4134. Epub 2019 Mar 14.
137 Lysosome-associated membrane protein 2 (LAMP-2) expression induced by miR-194-5p downregulation contributes to sunitinib resistance in human renal cell carcinoma cells.Oncol Lett. 2018 Jan;15(1):893-900. doi: 10.3892/ol.2017.7423. Epub 2017 Nov 15.
138 p38gamma overexpression promotes renal cell carcinoma cell growth, proliferation and migration.Biochem Biophys Res Commun. 2019 Aug 20;516(2):466-473. doi: 10.1016/j.bbrc.2019.06.056. Epub 2019 Jun 20.
139 A General Framework for Interrogation of mRNA Stability Programs Identifies RNA-Binding Proteins that Govern Cancer Transcriptomes.Cell Rep. 2018 May 8;23(6):1639-1650. doi: 10.1016/j.celrep.2018.04.031.
140 Expression of CK19, CD105 and CD146 are associated with early metastasis in patients with renal cell carcinoma.Oncol Lett. 2018 Apr;15(4):4229-4234. doi: 10.3892/ol.2018.7871. Epub 2018 Jan 26.
141 Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity.J Exp Clin Cancer Res. 2018 Dec 4;37(1):297. doi: 10.1186/s13046-018-0952-7.
142 Phosphodiesterase 10A IgG: A novel biomarker of paraneoplastic neurologic autoimmunity.Neurology. 2019 Aug 20;93(8):e815-e822. doi: 10.1212/WNL.0000000000007971. Epub 2019 Jul 17.
143 Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin.Cancer Sci. 2018 Jun;109(6):1865-1875. doi: 10.1111/cas.13609. Epub 2018 May 25.
144 Expression of Wip1 in kidney carcinoma and its correlation with tumor metastasis and clinical significance.Pathol Oncol Res. 2015 Jan;21(1):219-24. doi: 10.1007/s12253-014-9811-9. Epub 2014 Jun 28.
145 Nuclear factor-kappa B subunits and their prognostic cancer-specific survival value in renal cell carcinoma patients.Pathology. 2018 Aug;50(5):511-518. doi: 10.1016/j.pathol.2018.03.003. Epub 2018 Jun 21.
146 PTEN expression and mutations in TSC1, TSC2 and MTOR are associated with response to rapalogs in patients with renal cell carcinoma.Int J Cancer. 2020 Mar 1;146(5):1435-1444. doi: 10.1002/ijc.32579. Epub 2019 Aug 9.
147 Rce1 expression in renal cell carcinoma and its regulatory effect on 786-O cell apoptosis through endoplasmic reticulum stress.Acta Biochim Biophys Sin (Shanghai). 2017 Mar 1;49(3):254-261. doi: 10.1093/abbs/gmx002.
148 Androgen receptor regulates ASS1P3/miR-34a-5p/ASS1 signaling to promote renal cell carcinoma cell growth.Cell Death Dis. 2019 Apr 18;10(5):339. doi: 10.1038/s41419-019-1330-x.
149 Ribonucleotide reductase subunit M2 as a novel target for clear-cell renal cell carcinoma.Onco Targets Ther. 2019 Apr 30;12:3267-3275. doi: 10.2147/OTT.S196347. eCollection 2019.
150 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.Nat Commun. 2017 Jun 9;8:15724. doi: 10.1038/ncomms15724.
151 MicroRNA-186 Suppresses Cell Proliferation and Metastasis Through Targeting Sentrin-Specific Protease 1 in Renal Cell Carcinoma.Oncol Res. 2018 Mar 5;26(2):249-259. doi: 10.3727/096504017X14953948675430. Epub 2017 May 21.
152 Integrated Genomic and Proteomic Analyses Reveal Novel Mechanisms of the Methyltransferase SETD2 in Renal Cell Carcinoma Development.Mol Cell Proteomics. 2019 Mar;18(3):437-447. doi: 10.1074/mcp.RA118.000957. Epub 2018 Nov 28.
153 Clinicopathologic and Molecular Pathology of Collecting Duct Carcinoma and Related Renal Cell Carcinomas.Adv Anat Pathol. 2017 Mar;24(2):65-77. doi: 10.1097/PAP.0000000000000138.
154 Long noncoding RNA HOTAIR promotes renal cell carcinoma malignancy through alpha-2, 8-sialyltransferase 4 by sponging microRNA-124.Cell Prolif. 2018 Dec;51(6):e12507. doi: 10.1111/cpr.12507. Epub 2018 Aug 13.
155 The importance of serum osteopontin and stanniocalcin-1 in renal cell carcinoma.Neoplasma. 2018 Nov 15;65(6):958-964. doi: 10.4149/neo_2018_171123N759. Epub 2018 Jun 18.
156 STK39 blockage by RNA interference inhibits the proliferation and induces the apoptosis of renal cell carcinoma.Onco Targets Ther. 2018 Mar 16;11:1511-1519. doi: 10.2147/OTT.S153806. eCollection 2018.
157 Risk factors for sorafenib-induced high-grade skin rash in Japanese patients with advanced renal cell carcinoma. Anticancer Drugs. 2013 Mar;24(3):310-4.
158 Racial/ethnic disparities in renal cell carcinoma: Increased risk of early-onset and variation in histologic subtypes.Cancer Med. 2019 Nov;8(15):6780-6788. doi: 10.1002/cam4.2552. Epub 2019 Sep 11.
159 Establishment of two human renal cell carcinoma cell lines with different chemosensitivity.Hum Cell. 1996 Jun;9(2):101-8.
160 LncRNA MALAT1 modified progression of clear cell kidney carcinoma (KIRC) by regulation of miR-194-5p/ACVR2B signaling.Mol Carcinog. 2019 Feb;58(2):279-292. doi: 10.1002/mc.22926. Epub 2018 Oct 31.
161 Increased mRNA expression of ADAMs in renal cell carcinoma and their association with clinical outcome.Oncol Rep. 2004 Feb;11(2):529-36.
162 Changes in expressions of ADAM9, 10, and 17 as well as -secretase activity in renal cell carcinoma.Urol Oncol. 2017 Jan;35(1):36.e15-36.e22. doi: 10.1016/j.urolonc.2016.08.010. Epub 2016 Sep 28.
163 The Adenosine A1 Receptor Antagonist DPCPX Inhibits Tumor Progression via the ERK/JNK Pathway in Renal Cell Carcinoma.Cell Physiol Biochem. 2017;43(2):733-742. doi: 10.1159/000481557. Epub 2017 Sep 27.
164 Identification of Novel Proteins Interacting with Vascular Endothelial Growth Inhibitor 174 in Renal Cell Carcinoma.Anticancer Res. 2017 Aug;37(8):4379-4388. doi: 10.21873/anticanres.11832.
165 Comprehensive analysis of 5-aminolevulinic acid dehydrogenase (ALAD) variants and renal cell carcinoma risk among individuals exposed to lead.PLoS One. 2011;6(7):e20432. doi: 10.1371/journal.pone.0020432. Epub 2011 Jul 20.
166 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway.Oncol Rep. 2005 Jul;14(1):73-9.
167 Overexpression of integrin-associated protein (CD47) in rat kidney treated with a renal carcinogen, ferric nitrilotriacetate.Jpn J Cancer Res. 1997 Feb;88(2):120-8. doi: 10.1111/j.1349-7006.1997.tb00356.x.
168 Angiomotin Family Members: Oncogenes or Tumor Suppressors?.Int J Biol Sci. 2017 Jun 1;13(6):772-781. doi: 10.7150/ijbs.19603. eCollection 2017.
169 Determination of angiogenic factors in serum by protein array in patients with renal cell carcinoma.Folia Biol (Praha). 2008;54(4):134-40.
170 ANGPTL3 inhibits renal cell carcinoma metastasis by inhibiting VASP phosphorylation.Biochem Biophys Res Commun. 2019 Aug 27;516(3):880-887. doi: 10.1016/j.bbrc.2019.06.120. Epub 2019 Jun 30.
171 Serum level of ANGPTL4 as a potential biomarker in renal cell carcinoma.Urol Oncol. 2017 May;35(5):279-285. doi: 10.1016/j.urolonc.2016.12.017. Epub 2017 Jan 19.
172 AnnexinA1 expression is correlated with malignant potential of renal cell carcinoma.Int J Urol. 2019 Feb;26(2):284-290. doi: 10.1111/iju.13869. Epub 2018 Dec 2.
173 Annexin A2 in renal cell carcinoma: expression, function, and prognostic significance.Urol Oncol. 2015 Jan;33(1):22.e11-22.e21. doi: 10.1016/j.urolonc.2014.08.015. Epub 2014 Oct 3.
174 PCR-based RFLP screening of the commonly deleted 3p loci in renal cortical neoplasms.Diagn Mol Pathol. 1993 Dec;2(4):269-76.
175 Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease.FEBS Lett. 2012 Apr 5;586(7):947-55. doi: 10.1016/j.febslet.2012.03.002. Epub 2012 Mar 8.
176 Reduced L/B/K alkaline phosphatase gene expression in renal cell carcinoma: plausible role in tumorigenesis.Biochimie. 2014 Sep;104:27-35. doi: 10.1016/j.biochi.2014.05.011. Epub 2014 Jun 5.
177 Autophagy suppresses the proliferation of renal carcinoma cell.Eur Rev Med Pharmacol Sci. 2018 Jan;22(2):343-350. doi: 10.26355/eurrev_201801_14178.
178 AMPK as a therapeutic target in renal cell carcinoma.Cancer Biol Ther. 2010 Dec 1;10(11):1168-77. doi: 10.4161/cbt.10.11.13629. Epub 2010 Dec 1.
179 Combined assessment of low PGRMC1/positive ATP1A1 levels has enhanced prognostic value for renal cell carcinoma.Oncol Rep. 2018 Sep;40(3):1467-1476. doi: 10.3892/or.2018.6541. Epub 2018 Jul 2.
180 Targeting the TR4 nuclear receptor-mediated lncTASR/AXL signaling with tretinoin increases the sunitinib sensitivity to better suppress the RCC progression.Oncogene. 2020 Jan;39(3):530-545. doi: 10.1038/s41388-019-0962-8. Epub 2019 Sep 9.
181 Targeting beta2-microglobulin mediated signaling as a novel therapeutic approach for human renal cell carcinoma.J Urol. 2007 Jul;178(1):292-300. doi: 10.1016/j.juro.2007.03.007. Epub 2007 May 17.
182 Clinical significance and expression of PUMA, MCL-1, and p53 in human renal cell carcinoma and para-carcinoma tissues.Genet Mol Res. 2017 Jul 6;16(3). doi: 10.4238/gmr16039278.
183 LncRNA RP11-436H11.5, functioning as a competitive endogenous RNA, upregulates BCL-W expression by sponging miR-335-5p and promotes proliferation and invasion in renal cell carcinoma.Mol Cancer. 2017 Oct 25;16(1):166. doi: 10.1186/s12943-017-0735-3.
184 Expression parameters of the inhibitors of apoptosis cIAP1 and cIAP2 in renal cell carcinomas and their prognostic relevance.Int J Cancer. 2007 Mar 1;120(5):1081-6. doi: 10.1002/ijc.22416.
185 Expression of Livin and PlGF in human osteosarcoma is associated with tumor progression and clinical outcome.Oncol Lett. 2018 Oct;16(4):4953-4960. doi: 10.3892/ol.2018.9239. Epub 2018 Jul 31.
186 Different Cytokine and Chemokine Expression Patterns in Malignant Compared to Those in Nonmalignant Renal Cells.Anal Cell Pathol (Amst). 2017;2017:7190546. doi: 10.1155/2017/7190546. Epub 2017 Jul 9.
187 Decreased expression of bone morphogenetic protein (BMP) receptor type II correlates with insensitivity to BMP-6 in human renal cell carcinoma cells.Clin Cancer Res. 2003 Dec 1;9(16 Pt 1):6046-51.
188 The expression and role of tyrosine kinase ETK/BMX in renal cell carcinoma.J Exp Clin Cancer Res. 2014 Mar 7;33(1):25. doi: 10.1186/1756-9966-33-25.
189 Expression and clinical significance of CD147 in renal cell carcinoma: a meta-analysis.Oncotarget. 2017 Apr 10;8(31):51331-51344. doi: 10.18632/oncotarget.17376. eCollection 2017 Aug 1.
190 The Expression of BTS-2 Enhances Cell Growth and Invasiveness in Renal Cell Carcinoma.Anticancer Res. 2017 Jun;37(6):2853-2860. doi: 10.21873/anticanres.11637.
191 B cell translocation gene 1 reduces the biological outcome of kidney cancer through induction of cell proliferation, cell cycle arrest, cell apoptosis and cell metastasis.Int J Mol Med. 2015 Mar;35(3):777-83. doi: 10.3892/ijmm.2014.2058. Epub 2014 Dec 31.
192 Association of 3' nearby gene BTLA polymorphisms with the risk of renal cell carcinoma in the Polish population.Urol Oncol. 2016 Sep;34(9):419.e13-9. doi: 10.1016/j.urolonc.2016.04.010. Epub 2016 May 24.
193 Overexpression of the mitotic checkpoint genes BUB1 and BUBR1 is associated with genomic complexity in clear cell kidney carcinomas.Cell Oncol. 2008;30(5):389-95. doi: 10.3233/clo-2008-0439.
194 C1QBP suppresses cell adhesion and metastasis of renal carcinoma cells.Sci Rep. 2017 Apr 20;7(1):999. doi: 10.1038/s41598-017-01084-w.
195 Effects of von Hippel-Lindau gene mutation and methylation status on expression of transmembrane carbonic anhydrases in renal cell carcinoma.J Cancer Res Clin Oncol. 2002 Oct;128(10):561-8. doi: 10.1007/s00432-002-0374-x. Epub 2002 Aug 30.
196 Transcript levels of aquaporin 1 and carbonic anhydrase IV as predictive indicators for prognosis of renal cell carcinoma patients after nephrectomy.Int J Cancer. 1998 Feb 20;79(1):1-7. doi: 10.1002/(sici)1097-0215(19980220)79:1<1::aid-ijc1>3.0.co;2-5.
197 CAIX-specific CAR-T Cells and Sunitinib Show Synergistic Effects Against Metastatic Renal Cancer Models.J Immunother. 2020 Jan;43(1):16-28. doi: 10.1097/CJI.0000000000000301.
198 Expression of calpain I messenger RNA in human renal cell carcinoma: correlation with lymph node metastasis and histological type.Int J Cancer. 1999 Feb 19;84(1):6-9. doi: 10.1002/(sici)1097-0215(19990219)84:1<6::aid-ijc2>3.0.co;2-t.
199 Overexpression of CAPN2 promotes cell metastasis and proliferation via AKT/mTOR signaling in renal cell carcinoma.Oncotarget. 2017 Oct 26;8(58):97811-97821. doi: 10.18632/oncotarget.22083. eCollection 2017 Nov 17.
200 PIDDosome expression and the role of caspase-2 activation for chemotherapy-induced apoptosis in RCCs.Cell Oncol. 2010;32(1-2):29-42. doi: 10.3233/CLO-2009-0492.
201 Improvement of doxorubicin efficacy using liposomal anti-polo-like kinase 1 siRNA in human renal cell carcinomas.Mol Pharm. 2014 Aug 4;11(8):2713-9. doi: 10.1021/mp500245z. Epub 2014 May 12.
202 Overexpression of cyclin D1, D3, and p21 in an infantile renal carcinoma with Xp11.2 TFE3-gene fusion.Pathol Res Pract. 2008;204(8):589-97. doi: 10.1016/j.prp.2008.01.010. Epub 2008 Mar 20.
203 Up-regulation of functional chemokine receptor CCR3 in human renal cell carcinoma.Clin Cancer Res. 2005 Apr 1;11(7):2459-65. doi: 10.1158/1078-0432.CCR-04-0405.
204 Human renal cell carcinoma induces a dendritic cell subset that uses T-cell crosstalk for tumor-permissive milieu alterations.Am J Pathol. 2011 Jul;179(1):436-51. doi: 10.1016/j.ajpath.2011.03.011. Epub 2011 May 18.
205 Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis.Cancer Lett. 2017 Apr 10;391:50-58. doi: 10.1016/j.canlet.2017.01.007. Epub 2017 Jan 17.
206 Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma.Cancer Manag Res. 2019 Jul 25;11:7021-7030. doi: 10.2147/CMAR.S209205. eCollection 2019.
207 Proximal CD13 Versus Distal GATA-3 Expression in Renal Neoplasia According to WHO 2016 Classification.Appl Immunohistochem Mol Morphol. 2018 May/Jun;26(5):316-323. doi: 10.1097/PAI.0000000000000435.
208 Expression of CD3 antigens in renal tubule epithelium and renal oncocytomas.Pathol Res Pract. 2005;201(12):803-8. doi: 10.1016/j.prp.2005.09.003. Epub 2005 Nov 3.
209 First-in-human study to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of the anti-CD27L antibody-drug conjugate AMG 172 in patients with relapsed/refractory renal cell carcinoma.Cancer Chemother Pharmacol. 2019 Jun;83(6):1057-1063. doi: 10.1007/s00280-019-03796-4. Epub 2019 Mar 26.
210 Up-regulation of vascular endothelial growth factor-D expression in clear cell renal cell carcinoma by CD74: a critical role in cancer cell tumorigenesis.J Immunol. 2008 Nov 1;181(9):6584-94. doi: 10.4049/jimmunol.181.9.6584.
211 CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma.BMC Cancer. 2015 Dec 1;15:942. doi: 10.1186/s12885-015-1951-0.
212 Knockdown of Cdc25B in renal cell carcinoma is associated with decreased malignant features.Asian Pac J Cancer Prev. 2012;13(3):931-5. doi: 10.7314/apjcp.2012.13.3.931.
213 Functional loss of E-cadherin and cadherin-11 alleles on chromosome 16q22 in colonic cancer.J Pathol. 1999 Apr;187(5):530-4. doi: 10.1002/(SICI)1096-9896(199904)187:5<530::AID-PATH293>3.0.CO;2-C.
214 MicroRNA-720 Regulates E-cadherin-E-catenin Complex and Promotes Renal Cell Carcinoma.Mol Cancer Ther. 2017 Dec;16(12):2840-2848. doi: 10.1158/1535-7163.MCT-17-0400. Epub 2017 Aug 11.
215 MiR-31-5p acts as a tumor suppressor in renal cell carcinoma by targeting cyclin-dependent kinase 1 (CDK1).Biomed Pharmacother. 2019 Mar;111:517-526. doi: 10.1016/j.biopha.2018.12.102. Epub 2018 Dec 28.
216 Wilms' tumor 1-associating protein promotes renal cell carcinoma proliferation by regulating CDK2 mRNA stability.J Exp Clin Cancer Res. 2018 Feb 27;37(1):40. doi: 10.1186/s13046-018-0706-6.
217 Major role for a 3p21 region and lack of involvement of the t(3;8) breakpoint region in the development of renal cell carcinoma suggested by loss of heterozygosity analysis.Genes Chromosomes Cancer. 1996 Jan;15(1):64-72. doi: 10.1002/(SICI)1098-2264(199601)15:1<64::AID-GCC9>3.0.CO;2-2.
218 The covalent CDK7 inhibitor THZ1 enhances temsirolimus-induced cytotoxicity via autophagy suppression in human renal cell carcinoma.Cancer Lett. 2020 Feb 28;471:27-37. doi: 10.1016/j.canlet.2019.12.005. Epub 2019 Dec 6.
219 Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome.Int J Cancer. 2014 Sep 15;135(6):1330-42. doi: 10.1002/ijc.28768. Epub 2014 May 2.
220 Immunohistochemical study of cyclin A and p16 expression in patients with renal cell carcinoma.J BUON. 2017 Sep-Oct;22(5):1322-1327.
221 The tumour suppressor gene CEACAM1 is completely but reversibly downregulated in renal cell carcinoma.J Pathol. 2004 Nov;204(3):258-67. doi: 10.1002/path.1657.
222 Protein gene product 9.5 is diagnostically helpful in delineating high-grade renal cell cancer involving the renal medullary/sinus region from invasive urothelial cell carcinoma of the renal pelvis.Hum Pathol. 2013 May;44(5):712-7. doi: 10.1016/j.humpath.2012.07.024. Epub 2012 Nov 14.
223 Expression of the free beta-subunit of human chorionic gonadotropin in renal cell carcinoma: prognostic study on tissue and serum.Int J Cancer. 2003 May 1;104(5):631-5. doi: 10.1002/ijc.11000.
224 CSN5 promotes renal cell carcinoma metastasis and EMT by inhibiting ZEB1 degradation.Biochem Biophys Res Commun. 2017 Jun 17;488(1):101-108. doi: 10.1016/j.bbrc.2017.05.016. Epub 2017 May 4.
225 Integrative analysis reveals CRHBP inhibits renal cell carcinoma progression by regulating inflammation and apoptosis.Cancer Gene Ther. 2020 Aug;27(7-8):607-618. doi: 10.1038/s41417-019-0138-2. Epub 2019 Oct 1.
226 Urocortin and corticotropin-releasing factor receptor 2 in human renal cell carcinoma: disruption of an endogenous inhibitor of angiogenesis and proliferation.World J Urol. 2009 Dec;27(6):825-30. doi: 10.1007/s00345-009-0417-x.
227 The Vitamin D status is associated with serum C-reactive protein and adhesion molecules in patients with renal cell carcinoma.Sci Rep. 2019 Nov 13;9(1):16719. doi: 10.1038/s41598-019-53395-9.
228 Differential protein profiling in renal-cell carcinoma.Mol Carcinog. 2004 May;40(1):47-61. doi: 10.1002/mc.20015.
229 Expression of NAD(P)H:quinone oxidoreductase and glutathione S-transferases alpha and pi in human renal cell carcinoma and in kidney cancer-derived cell lines.Carcinogenesis. 1994 Feb;15(2):219-25. doi: 10.1093/carcin/15.2.219.
230 DNA ploidy of oncocytic-granular renal cell carcinomas and renal oncocytomas by image analysis.Arch Pathol Lab Med. 1992 Feb;116(2):154-8.
231 Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.Nat Genet. 2011 Dec 4;44(1):17-9. doi: 10.1038/ng.1014.
232 CXCR3-B expression correlates with tumor necrosis extension in renal cell carcinoma.J Urol. 2009 Feb;181(2):843-8. doi: 10.1016/j.juro.2008.10.063. Epub 2008 Dec 17.
233 Galectin-3 promotes CXCR2 to augment the stem-like property of renal cell carcinoma.J Cell Mol Med. 2018 Dec;22(12):5909-5918. doi: 10.1111/jcmm.13860. Epub 2018 Sep 24.
234 Immunohistochemical distinction of metastases of renal cell carcinoma with molecular analysis of overexpression of the chemokines CXCR2 and CXCR3 as independent positive prognostic factors for the tumorigenesis.IUBMB Life. 2016 Aug;68(8):629-33. doi: 10.1002/iub.1520. Epub 2016 Jun 6.
235 Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma. Oncotarget. 2015 Apr 10;6(10):7774-87.
236 Vitamin D hydroxylases CYP2R1, CYP27B1 and CYP24A1 in renal cell carcinoma.Eur J Clin Invest. 2013 Dec;43(12):1282-90. doi: 10.1111/eci.12176. Epub 2013 Oct 12.
237 Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study.Lancet Oncol. 2011 Nov;12(12):1143-50. doi: 10.1016/S1470-2045(11)70266-2. Epub 2011 Oct 17.
238 L-DOPA decarboxylase mRNA levels provide high diagnostic accuracy and discrimination between clear cell and non-clear cell subtypes in renal cell carcinoma.Clin Biochem. 2015 Jun;48(9):590-5. doi: 10.1016/j.clinbiochem.2015.02.007. Epub 2015 Feb 23.
239 Renal carcinoma cells undergo apoptosis without oligonucleosomal DNA fragmentation.Biochem Biophys Res Commun. 2004 Jun 4;318(3):710-3. doi: 10.1016/j.bbrc.2004.04.086.
240 Expression levels of the mitochondrial IAP antagonists Smac/DIABLO and Omi/HtrA2 in clear-cell renal cell carcinomas and their prognostic value.J Cancer Res Clin Oncol. 2008 May;134(5):543-50. doi: 10.1007/s00432-007-0317-7. Epub 2007 Oct 9.
241 MicroRNA-183 promotes the proliferation and metastasis of renal cell carcinoma through targeting Dickkopf-related protein 3.Oncol Lett. 2018 Apr;15(4):6003-6008. doi: 10.3892/ol.2018.7998. Epub 2018 Feb 8.
242 Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma.Hum Mol Genet. 2006 Mar 15;15(6):821-30. doi: 10.1093/hmg/ddl001. Epub 2006 Jan 26.
243 Characterisation of gamma delta T cells in renal cell carcinoma patients by polymerase chain reaction analysis of T cell receptor transcripts.Cancer Immunol Immunother. 1997 Mar;44(1):27-34. doi: 10.1007/s002620050351.
244 HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.Cancer Res. 2012 Jun 1;72(11):2844-54. doi: 10.1158/0008-5472.CAN-11-3062. Epub 2012 May 2.
245 Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers.Pathol Oncol Res. 2020 Jul;26(3):1539-1547. doi: 10.1007/s12253-019-00734-w. Epub 2019 Sep 2.
246 Decreased expression of dual-specificity phosphatase 9 is associated with poor prognosis in clear cell renal cell carcinoma.BMC Cancer. 2011 Sep 26;11:413. doi: 10.1186/1471-2407-11-413.
247 A novel human lncRNA SANT1 cis-regulates the expression of SLC47A2 by altering SFPQ/E2F1/HDAC1 binding to the promoter region in renal cell carcinoma. RNA Biol. 2019 Jul;16(7):940-949.
248 MicroRNA-429 suppresses cell proliferation, epithelial-mesenchymal transition, and metastasis by direct targeting of BMI1 and E2F3 in renal cell carcinoma.Urol Oncol. 2015 Jul;33(7):332.e9-18. doi: 10.1016/j.urolonc.2015.03.016. Epub 2015 May 4.
249 Modality of tumor endothelial VEGFR2 silencing-mediated improvement in intratumoral distribution of lipid nanoparticles.J Control Release. 2017 Apr 10;251:1-10. doi: 10.1016/j.jconrel.2017.02.010. Epub 2017 Feb 10.
250 Endothelin axis expression is markedly different in the two main subtypes of renal cell carcinoma.Cancer. 2004 May 15;100(10):2118-24. doi: 10.1002/cncr.20222.
251 Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2.Biochem Biophys Res Commun. 1995 Mar 17;208(2):721-7. doi: 10.1006/bbrc.1995.1397.
252 Targeting EGFL7 expression through RNA interference suppresses renal cell carcinoma growth by inhibiting angiogenesis.Asian Pac J Cancer Prev. 2014;15(7):3045-50. doi: 10.7314/apjcp.2014.15.7.3045.
253 Protein Kinase RNA-Like Endoplasmic Reticulum Kinase-Mediated Bcl-2 Protein Phosphorylation Contributes to Evodiamine-Induced Apoptosis of Human Renal Cell Carcinoma Cells.PLoS One. 2016 Aug 2;11(8):e0160484. doi: 10.1371/journal.pone.0160484. eCollection 2016.
254 The tumor suppressor NDRG2 cooperates with an mTORC1 inhibitor to suppress the Warburg effect in renal cell carcinoma.Invest New Drugs. 2020 Aug;38(4):956-966. doi: 10.1007/s10637-019-00839-8. Epub 2019 Aug 28.
255 Molecular cloning of the human kidney differentiation antigen gp160: human aminopeptidase A.Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7069-73. doi: 10.1073/pnas.90.15.7069.
256 Overexpression of autotaxin is associated with human renal cell carcinoma and bladder carcinoma and their progression.Med Oncol. 2016 Nov;33(11):131. doi: 10.1007/s12032-016-0836-7. Epub 2016 Oct 18.
257 Phase I Trials of Anti-ENPP3 Antibody-Drug Conjugates in Advanced Refractory Renal Cell Carcinomas.Clin Cancer Res. 2018 Sep 15;24(18):4399-4406. doi: 10.1158/1078-0432.CCR-18-0481. Epub 2018 May 30.
258 EphA2 Is a Potential Player of Malignant Cellular Behavior in Non-Metastatic Renal Cell Carcinoma Cells but Not in Metastatic Renal Cell Carcinoma Cells.PLoS One. 2015 Jul 15;10(7):e0130975. doi: 10.1371/journal.pone.0130975. eCollection 2015.
259 miR?5a?p acts as an oncogene in renal cell carcinoma.Mol Med Rep. 2017 Mar;15(3):1379-1386. doi: 10.3892/mmr.2017.6121. Epub 2017 Jan 16.
260 Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition.Growth Factors. 2014 Dec;32(6):202-6. doi: 10.3109/08977194.2014.980904. Epub 2014 Nov 13.
261 Identification of erythropoietin receptor-derived peptides having the potential to induce cancer-reactive cytotoxic T lymphocytes from HLA-A24(+) patients with renal cell carcinoma.Int Immunopharmacol. 2014 May;20(1):59-65. doi: 10.1016/j.intimp.2014.02.018. Epub 2014 Feb 26.
262 Comparative expression profiling for human endoplasmic reticulum-resident aminopeptidases 1 and 2 in normal kidney versus distinct renal cell carcinoma subtypes.Int J Clin Exp Pathol. 2013 May 15;6(6):998-1008. Print 2013.
263 HAF mediates the evasive resistance of anti-angiogenesis TKI through disrupting HIF-1 and HIF-2 balance in renal cell carcinoma.Oncotarget. 2017 Jul 25;8(30):49713-49724. doi: 10.18632/oncotarget.17923.
264 PAR-1- and PAR-3-type thrombin receptor expression in primary cultures of human renal cell carcinoma cells.Int J Oncol. 2002 Jan;20(1):177-80.
265 Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.Nat Genet. 2015 Jan;47(1):13-21. doi: 10.1038/ng.3146. Epub 2014 Nov 17.
266 Prevalence and prognostic value of FBXO11 expression in patients with clear cell renal cell carcinoma.BMC Cancer. 2019 Jun 3;19(1):534. doi: 10.1186/s12885-019-5736-8.
267 Deletion of chromosome 3p14.2-p25 involving the VHL and FHIT genes in conventional renal cell carcinoma.Cancer Res. 2003 Jan 15;63(2):455-7.
268 FKBP-12 exhibits an inhibitory activity on calcium oxalate crystal growth in vitro.J Korean Med Sci. 2002 Feb;17(1):41-8. doi: 10.3346/jkms.2002.17.1.41.
269 Impact of tivozanib on patient outcomes in treatment of advanced renal cell carcinoma.Cancer Manag Res. 2019 Aug 16;11:7779-7785. doi: 10.2147/CMAR.S206105. eCollection 2019.
270 PET imaging in renal cancer.Curr Opin Oncol. 2019 May;31(3):216-221. doi: 10.1097/CCO.0000000000000518.
271 FSCN1 predicts survival and is regulated by a PI3K-dependent mechanism in renal cell carcinoma.J Cell Physiol. 2018 Jun;233(6):4748-4758. doi: 10.1002/jcp.26264. Epub 2018 Jan 15.
272 Value of Ferritin Heavy Chain (FTH1) Expression in Diagnosis and Prognosis of Renal Cell Carcinoma.Med Sci Monit. 2019 May 19;25:3700-3715. doi: 10.12659/MSM.914162.
273 MicroRNA?13 inhibits proliferation and invasion of renal cell carcinoma cells through targeting FZD7.Mol Med Rep. 2017 Oct;16(4):4279-4286. doi: 10.3892/mmr.2017.7076. Epub 2017 Jul 24.
274 The interaction of YBX1 with G3BP1 promotes renal cell carcinoma cell metastasis via YBX1/G3BP1-SPP1- NF-B signaling axis.J Exp Clin Cancer Res. 2019 Sep 3;38(1):386. doi: 10.1186/s13046-019-1347-0.
275 SCP phosphatases suppress renal cell carcinoma by stabilizing PML and inhibiting mTOR/HIF signaling.Cancer Res. 2014 Dec 1;74(23):6935-46. doi: 10.1158/0008-5472.CAN-14-1330. Epub 2014 Oct 7.
276 S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma.Cancer Res. 2019 Nov 15;79(22):5758-5768. doi: 10.1158/0008-5472.CAN-19-1366. Epub 2019 Oct 4.
277 Ghrelin promotes renal cell carcinoma metastasis via Snail activation and is associated with poor prognosis.J Pathol. 2015 Sep;237(1):50-61. doi: 10.1002/path.4552. Epub 2015 May 28.
278 Identification of key genes and pathways in renal cell carcinoma through expression profiling data.Kidney Blood Press Res. 2015;40(3):288-97. doi: 10.1159/000368504. Epub 2015 May 27.
279 VHL-dependent regulation of a -dystroglycan glycoform and glycogene expression in renal cancer.Int J Oncol. 2013 Nov;43(5):1368-76. doi: 10.3892/ijo.2013.2066. Epub 2013 Aug 21.
280 TGR5 expression in normal kidney and renal neoplasms.Diagn Pathol. 2018 Apr 2;13(1):22. doi: 10.1186/s13000-018-0700-5.
281 Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by targeting the ERK/MAPK pathway.Oncotarget. 2016 Sep 27;7(39):63374-63387. doi: 10.18632/oncotarget.11463.
282 GRK5 promotes tumor progression in renal cell carcinoma.Neoplasma. 2019 Feb 6;66(2):261-270. doi: 10.4149/neo_2018_180621N409.
283 Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.Oncogene. 2013 Sep 12;32(37):4366-76. doi: 10.1038/onc.2012.471. Epub 2012 Oct 22.
284 Expression of gastrin releasing Peptide receptor in renal cell carcinomas: a potential function for the regulation of neoangiogenesis and microvascular perfusion.J Urol. 2005 Jun;173(6):2154-9. doi: 10.1097/01.ju.0000158135.26893.bc.
285 Signal integration and gene induction by a functionally distinct STAT3 phosphoform.Mol Cell Biol. 2014 May;34(10):1800-11. doi: 10.1128/MCB.00034-14. Epub 2014 Mar 10.
286 Concomitance of Polymorphisms in Glutathione Transferase Omega Genes Is Associated with Risk of Clear Cell Renal Cell Carcinoma.Tohoku J Exp Med. 2018 Sep;246(1):35-44. doi: 10.1620/tjem.246.35.
287 Hepatocyte growth factor activator inhibitor types 1 and 2 are expressed by tubular epithelium in kidney and down-regulated in renal cell carcinoma.J Urol. 2004 Feb;171(2 Pt 1):890-6. doi: 10.1097/01.ju.0000092861.21122.d2.
288 Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma.Oncotarget. 2016 May 3;7(18):26866-78. doi: 10.18632/oncotarget.8567.
289 Silencing of tumor-suppressive NR_023387 in renal cell carcinoma via promoter hypermethylation and HNF4A deficiency.J Cell Physiol. 2020 Mar;235(3):2113-2128. doi: 10.1002/jcp.29115. Epub 2019 Aug 20.
290 Tumor-suppressive function and mechanism of HOXB13 in right-sided colon cancer.Signal Transduct Target Ther. 2019 Nov 29;4:51. doi: 10.1038/s41392-019-0086-1. eCollection 2019.
291 Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture.Cancer Res. 2006 Apr 1;66(7):3611-9. doi: 10.1158/0008-5472.CAN-05-2983.
292 Mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type II expression in renal cell neoplasms: a tissue microarray and quantitative RT-PCR study.Am J Surg Pathol. 2008 Jun;32(6):874-83. doi: 10.1097/PAS.0b013e31815f2362.
293 Recent developments in small molecule therapies for renal cell carcinoma.Eur J Med Chem. 2017 Dec 15;142:383-392. doi: 10.1016/j.ejmech.2017.08.007. Epub 2017 Aug 9.
294 Serum interferon alpha receptor 2 mRNA may predict efficacy of interferon alpha with/without low-dose sorafenib for metastatic clear cell renal cell carcinoma.Cancer Immunol Immunother. 2011 Jun;60(6):793-808. doi: 10.1007/s00262-011-0989-3. Epub 2011 Feb 25.
295 Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma.Signal Transduct Target Ther. 2019 Jan 25;4:2. doi: 10.1038/s41392-019-0035-z. eCollection 2019.
296 Long non-coding RNA HOTAIR promotes cell migration by upregulating insulin growth factor-binding protein 2 in renal cell carcinoma.Sci Rep. 2017 Sep 20;7(1):12016. doi: 10.1038/s41598-017-12191-z.
297 Altered messenger RNA and protein expressions for insulin-like growth factor family members in clear cell and papillary renal cell carcinomas.Int J Urol. 2005 Jan;12(1):17-28. doi: 10.1111/j.1442-2042.2004.00993.x.
298 Mechanisms regulating PD-L1 expression on tumor and immune cells.J Immunother Cancer. 2019 Nov 15;7(1):305. doi: 10.1186/s40425-019-0770-2.
299 Immunotherapy for genitourinary tumors.Int J Urol. 2019 Mar;26(3):326-333. doi: 10.1111/iju.13902. Epub 2019 Feb 1.
300 Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery.Cancer Biol Ther. 2010 Dec 15;10(12):1290-305. doi: 10.4161/cbt.10.12.13497. Epub 2010 Dec 15.
301 Polymorphism rs4787951 in IL-4R contributes to the increased risk of renal cell carcinoma in a Chinese population.Gene. 2019 Feb 15;685:242-247. doi: 10.1016/j.gene.2018.11.070. Epub 2018 Nov 23.
302 Oleic acid promotes cell invasion through an integrin-linked kinase signaling pathway in renal cell carcinoma.Nutr Cancer. 2020;72(6):968-975. doi: 10.1080/01635581.2019.1669672. Epub 2019 Oct 1.
303 Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor.Mol Cell Biol. 2009 Apr;29(7):1707-18. doi: 10.1128/MCB.01184-07. Epub 2009 Jan 21.
304 Inverse relationship between insulin receptor expression and progression in renal cell carcinoma.Oncol Rep. 2017 May;37(5):2929-2941. doi: 10.3892/or.2017.5552. Epub 2017 Apr 5.
305 Tumor-associated macrophage expression of interferon regulatory Factor-8 (IRF8) is a predictor of progression and patient survival in renal cell carcinoma.J Immunother Cancer. 2019 Jun 20;7(1):155. doi: 10.1186/s40425-019-0630-0.
306 Altered expression of beta 1 integrins in renal carcinoma cell lines exposed to vinblastine.Anticancer Res. 1999 Mar-Apr;19(2C):1509-12.
307 Integrin signaling potentiates transforming growth factor-beta 1 (TGF-1) dependent down-regulation of E-Cadherin expression - Important implications for epithelial to mesenchymal transition (EMT) in renal cell carcinoma.Exp Cell Res. 2017 Jun 15;355(2):57-66. doi: 10.1016/j.yexcr.2017.03.051. Epub 2017 Mar 29.
308 miR-17 inhibition enhances the formation of kidney cancer spheres with stem cell/ tumor initiating cell properties.Oncotarget. 2015 Mar 20;6(8):5567-81. doi: 10.18632/oncotarget.1901.
309 ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy.Cancer Res. 2014 Dec 1;74(23):6820-32. doi: 10.1158/0008-5472.CAN-14-0303. Epub 2014 Oct 8.
310 Sex specific associations in genome wide association analysis of renal cell carcinoma.Eur J Hum Genet. 2019 Oct;27(10):1589-1598. doi: 10.1038/s41431-019-0455-9. Epub 2019 Jun 23.
311 Methylation of the gamma-catenin gene is associated with poor prognosis of renal cell carcinoma.Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):557-64.
312 Integrated molecular analysis of clear-cell renal cell carcinoma.Nat Genet. 2013 Aug;45(8):860-7. doi: 10.1038/ng.2699. Epub 2013 Jun 24.
313 KDM3A is not associated with metastasis and prognosis of breast cancer.Oncol Lett. 2018 Jun;15(6):9751-9756. doi: 10.3892/ol.2018.8578. Epub 2018 Apr 25.
314 Renal cell neoplasms contain shared tumor type-specific copy number variations.Am J Pathol. 2012 Jun;180(6):2427-39. doi: 10.1016/j.ajpath.2012.01.044. Epub 2012 Apr 3.
315 Different expression patterns of histone H3K27 demethylases in renal cell carcinoma and bladder cancer.Cancer Biomark. 2017;18(2):125-131. doi: 10.3233/CBM-160003.
316 Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells.Eur J Med Chem. 2019 Oct 1;179:347-357. doi: 10.1016/j.ejmech.2019.06.060. Epub 2019 Jun 23.
317 The expression of ketohexokinase is diminished in human clear cell type of renal cell carcinoma.Proteomics. 2006 Feb;6(3):1077-84. doi: 10.1002/pmic.200401345.
318 Killer inhibitory receptor (CD158b) modulates the lytic activity of tumor-specific T lymphocytes infiltrating renal cell carcinomas.Blood. 2000 May 1;95(9):2883-9.
319 miR-21 downregulated TCF21 to inhibit KISS1 in renal cancer.Urology. 2012 Dec;80(6):1298-302.e1. doi: 10.1016/j.urology.2012.08.013.
320 Lack of KISS1R expression is associated with rapid progression of conventional renal cell carcinomas.J Pathol. 2011 Jan;223(1):46-53. doi: 10.1002/path.2764.
321 Expression of KIT (CD117) in renal cell carcinoma and renal oncocytoma.Oncology. 2005;68(2-3):269-75. doi: 10.1159/000086783. Epub 2005 Jul 7.
322 Dysregulation of kallikrein-related peptidases in renal cell carcinoma: potential targets of miRNAs.Biol Chem. 2010 Apr;391(4):411-23. doi: 10.1515/BC.2010.041.
323 The human tissue kallikreins (KLKs 1-3) and a novel KLK1 mRNA transcript are expressed in a renal cell carcinoma cDNA library.Immunopharmacology. 1999 Dec;45(1-3):83-8. doi: 10.1016/s0162-3109(99)00059-4.
324 Incidental Detection of Thyroid Metastases From Renal Cell Carcinoma Using 68Ga-PSMA PET/CT to Assess Prostate Cancer Recurrence.Clin Nucl Med. 2017 Mar;42(3):221-222. doi: 10.1097/RLU.0000000000001522.
325 Functional characterization of BC039389-GATM and KLK4-KRSP1 chimeric read-through transcripts which are up-regulated in renal cell cancer.BMC Genomics. 2015 Mar 27;16(1):247. doi: 10.1186/s12864-015-1446-z.
326 Immunohistochemical analysis of kallikrein-related peptidases in the normal kidney and renal tumors: potential clinical implications.Biol Chem. 2010 Apr;391(4):403-9. doi: 10.1515/BC.2010.025.
327 Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma.Oncogene. 2011 Jun 9;30(23):2622-32. doi: 10.1038/onc.2010.638. Epub 2011 Jan 24.
328 PD-1 and LAG-3 Dominate Checkpoint Receptor-Mediated T-cell Inhibition in Renal Cell Carcinoma.Cancer Immunol Res. 2019 Nov;7(11):1891-1899. doi: 10.1158/2326-6066.CIR-19-0146. Epub 2019 Sep 4.
329 Detection of urinary survivin using a magnetic particles-based chemiluminescence immunoassay for the preliminary diagnosis of bladder cancer and renal cell carcinoma combined with LAPTM4B.Oncol Lett. 2018 May;15(5):7923-7933. doi: 10.3892/ol.2018.8317. Epub 2018 Mar 22.
330 Non-Invasive Assessment of Lactate Production and Compartmentalization in Renal Cell Carcinomas Using Hyperpolarized (13)C Pyruvate MRI.Cancers (Basel). 2018 Sep 5;10(9):313. doi: 10.3390/cancers10090313.
331 Expression and Distribution of Galectin-3 in Chromophobe and Papillary Carcinomas.Anticancer Res. 2018 Jan;38(1):259-263. doi: 10.21873/anticanres.12216.
332 Detection of dysregulated competing endogenous RNA modules associated with clear cell kidney carcinoma.Mol Med Rep. 2018 Aug;18(2):1963-1972. doi: 10.3892/mmr.2018.9189. Epub 2018 Jun 19.
333 Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Renal Cell Carcinoma Progression and Overall Survival: The Link to Plasma Circulating MiR-7 and MiR-221/222 Expression.PLoS One. 2015 Apr 24;10(4):e0103258. doi: 10.1371/journal.pone.0103258. eCollection 2014.
334 Cystinyl aminopeptidase activity is decreased in renal cell carcinomas.Regul Pept. 2007 Dec 4;144(1-3):56-61. doi: 10.1016/j.regpep.2007.06.002. Epub 2007 Jun 21.
335 Expression changes of the MAD mitotic checkpoint gene family in renal cell carcinomas characterized by numerical chromosome changes.Virchows Arch. 2007 Apr;450(4):379-85. doi: 10.1007/s00428-007-0386-7. Epub 2007 Feb 28.
336 Below Safety Limits, Every Unit of Glomerular Filtration Rate Counts: Assessing the Relationship Between Renal Function and Cancer-specific Mortality in Renal Cell Carcinoma.Eur Urol. 2018 Nov;74(5):661-667. doi: 10.1016/j.eururo.2018.07.029. Epub 2018 Aug 10.
337 Expression of MAGE genes in renal cell carcinoma.Int J Mol Med. 1998 Jul;2(1):57-60. doi: 10.3892/ijmm.2.1.57.
338 Knockdown of MAGEA6 Activates AMP-Activated Protein Kinase (AMPK) Signaling to Inhibit Human Renal Cell Carcinoma Cells.Cell Physiol Biochem. 2018;45(3):1205-1218. doi: 10.1159/000487452. Epub 2018 Feb 9.
339 Normal polymorphism in the incomplete trinucleotide repeat of the arginine-rich protein gene.Cancer Res. 1997 Jul 15;57(14):2888-9.
340 Monoamine Oxidase B in Renal Cell Carcinoma.Med Sci Monit. 2018 Aug 4;24:5422-5426. doi: 10.12659/MSM.909507.
341 The selective MEK1 inhibitor Selumetinib enhances the antitumor activity of everolimus against renal cell carcinoma in vitro and in vivo.Oncotarget. 2017 Mar 28;8(13):20825-20833. doi: 10.18632/oncotarget.15346.
342 GSTM1 genotype is an independent prognostic factor in clear cell renal cell carcinoma.Urol Oncol. 2017 Jun;35(6):409-417. doi: 10.1016/j.urolonc.2017.02.005. Epub 2017 Mar 9.
343 miR-144-3p serves as a tumor suppressor for renal cell carcinoma and inhibits its invasion and metastasis by targeting MAP3K8.Biochem Biophys Res Commun. 2016 Nov 4;480(1):87-93. doi: 10.1016/j.bbrc.2016.10.004. Epub 2016 Oct 4.
344 MicroRNA-148b enhances proliferation and apoptosis in human renal cancer cells via directly targeting MAP3K9.Mol Med Rep. 2016 Jan;13(1):83-90. doi: 10.3892/mmr.2015.4555. Epub 2015 Nov 11.
345 Macrophage inflammatory protein-1 delta: a novel osteoclast stimulating factor secreted by renal cell carcinoma bone metastasis.Cancer Res. 2008 Mar 1;68(5):1261-6. doi: 10.1158/0008-5472.CAN-07-6122.
346 The protease activated receptor 1 gene variation IVSn -14 A>T is associated with distant metastasis and cancer specific survival in renal cell carcinoma.J Urol. 2013 Oct;190(4):1392-7. doi: 10.1016/j.juro.2013.03.041. Epub 2013 Mar 19.
347 Expression of methionine adenosyltransferase 2A in renal cell carcinomas and potential mechanism for kidney carcinogenesis.BMC Cancer. 2014 Mar 17;14:196. doi: 10.1186/1471-2407-14-196.
348 Aspirin restores ABT-737-mediated apoptosis in human renal carcinoma cells.Biochem Biophys Res Commun. 2018 Jul 12;502(2):187-193. doi: 10.1016/j.bbrc.2018.05.142. Epub 2018 May 24.
349 MDM2-positive papillary sarcomatoid renal cell carcinoma: a potential diagnostic pitfall.Virchows Arch. 2020 May;476(5):783-786. doi: 10.1007/s00428-019-02703-9. Epub 2019 Nov 16.
350 Prognostic and clinicopathological value of Ki-67/MIB-1 expression in renal cell carcinoma: a meta-analysis based on 4579 individuals.Cancer Manag Res. 2017 Nov 21;9:679-689. doi: 10.2147/CMAR.S141670. eCollection 2017.
351 microRNA?45 inhibits cell proliferation, migration and invasion by targeting matrix metallopeptidase-11 in renal cell carcinoma.Mol Med Rep. 2014 Jul;10(1):393-8. doi: 10.3892/mmr.2014.2149. Epub 2014 Apr 15.
352 Expression of messenger RNAs for membrane-type 1, 2, and 3 matrix metalloproteinases in human renal cell carcinomas.J Urol. 1999 Sep;162(3 Pt 1):905-9. doi: 10.1097/00005392-199909010-00088.
353 Expression of RON Proto-oncogene in Renal Oncocytoma and Chromophobe Renal Cell Carcinoma.Am J Surg Pathol. 2004 Aug;28(8):1045-50. doi: 10.1097/01.pas.0000128661.58697.7d.
354 MicroRNA-384 Inhibits the Growth and Invasion of Renal Cell Carcinoma Cells by Targeting Astrocyte Elevated Gene 1.Oncol Res. 2018 Apr 10;26(3):457-466. doi: 10.3727/096504017X15035025554553. Epub 2017 Aug 25.
355 Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-B DNA-binding activity.J Pineal Res. 2016 Apr;60(3):277-90. doi: 10.1111/jpi.12308. Epub 2016 Feb 3.
356 An analysis of five clear cell papillary cystadenomas of mesosalpinx and broad ligament: four associated with von Hippel-Lindau disease and one aggressive sporadic type.Histopathology. 2012 Apr;60(5):748-57. doi: 10.1111/j.1365-2559.2011.04151.x. Epub 2012 Feb 1.
357 Expression of human mucin genes in normal kidney and renal cell carcinoma.Histopathology. 2002 May;40(5):450-7. doi: 10.1046/j.1365-2559.2002.01408.x.
358 The effect of a gene associated with retinoid-interferon-induced mortality 19 (GRIM-19) on STAT3-induced gene expression in renal carcinoma.J Biochem. 2018 Oct 1;164(4):285-294. doi: 10.1093/jb/mvy052.
359 MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma.Sci Rep. 2017 Jul 17;7(1):5599. doi: 10.1038/s41598-017-06098-y.
360 Increased Nek1 expression in renal cell carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment.Oncotarget. 2014 Jun 30;5(12):4283-94. doi: 10.18632/oncotarget.2005.
361 DNA methylation of neural EGFL like1 (NELL1) is associated with advanced disease and the metastatic state of renal cell cancer patients.Oncol Rep. 2018 Dec;40(6):3861-3868. doi: 10.3892/or.2018.6732. Epub 2018 Sep 24.
362 Metastatic renal cell carcinoma cells growing in 3D on polyDlysine or laminin present a stemlike phenotype and drug resistance.Oncol Rep. 2019 Nov;42(5):1878-1892. doi: 10.3892/or.2019.7321. Epub 2019 Sep 18.
363 Case-control analysis of nucleotide excision repair pathway and the risk of renal cell carcinoma.Carcinogenesis. 2008 Nov;29(11):2112-9. doi: 10.1093/carcin/bgn189. Epub 2008 Aug 18.
364 Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma.PLoS One. 2015 Jun 2;10(6):e0128308. doi: 10.1371/journal.pone.0128308. eCollection 2015.
365 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.Nat Biotechnol. 2016 Feb;34(2):155-63. doi: 10.1038/nbt.3391. Epub 2015 Nov 30.
366 Potential effect of tumor-specific Treg-targeted antibodies in the treatment of human cancers: A bioinformatics analysis.Oncoimmunology. 2017 Nov 9;7(2):e1387705. doi: 10.1080/2162402X.2017.1387705. eCollection 2018.
367 The impact of immunohistochemical staining with ezrin-carbonic anhydrase IX and neuropilin-2 on prognosis in patients with metastatic renal cell cancer receiving tyrosine kinase inhibitors.Tumour Biol. 2015 Nov;36(11):8471-8. doi: 10.1007/s13277-015-3589-6. Epub 2015 May 31.
368 hOGG1 Ser326Cys polymorphism and renal cell carcinoma risk in a Chinese population.DNA Cell Biol. 2011 May;30(5):317-21. doi: 10.1089/dna.2010.1135. Epub 2010 Dec 17.
369 LncRNA-SARCC suppresses renal cell carcinoma (RCC) progression via altering the androgen receptor(AR)/miRNA-143-3p signals.Cell Death Differ. 2017 Sep;24(9):1502-1517. doi: 10.1038/cdd.2017.74. Epub 2017 Jun 23.
370 microRNA-505 negatively regulates HMGB1 to suppress cell proliferation in renal cell carcinoma.J Cell Physiol. 2019 Sep;234(9):15025-15034. doi: 10.1002/jcp.28142. Epub 2019 Jan 15.
371 Tumor efficacy and biodistribution of linear polyethylenimine-cholesterol/DNA complexes.Mol Ther. 2004 Jun;9(6):837-45. doi: 10.1016/j.ymthe.2004.02.014.
372 Negative prognostic significance of primary cilia, CD8+ tumor infiltrating lymphocytes and PD1+ cells expression in clear cell renal cancer.J BUON. 2019 Jul-Aug;24(4):1644-1651.
373 Differential expressions of PD-1, PD-L1 and PD-L2 between primary and metastatic sites in renal cell carcinoma.BMC Cancer. 2019 Apr 16;19(1):360. doi: 10.1186/s12885-019-5578-4.
374 Identification and expression analysis of an N-terminally truncated isoform of human PDGF-C.Exp Cell Res. 2008 Aug 15;314(14):2529-43. doi: 10.1016/j.yexcr.2008.06.007. Epub 2008 Jun 13.
375 Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model.Cancer Res. 2005 Jul 1;65(13):5711-9. doi: 10.1158/0008-5472.CAN-04-4313.
376 Targeting Tyrosine kinases in Renal Cell Carcinoma: "New Bullets against Old Guys".Int J Mol Sci. 2019 Apr 17;20(8):1901. doi: 10.3390/ijms20081901.
377 PDZK1 inhibits the development and progression of renal cell carcinoma by suppression of SHP-1 phosphorylation.Oncogene. 2017 Nov 2;36(44):6119-6131. doi: 10.1038/onc.2017.199. Epub 2017 Jul 10.
378 Genetic variants in RKIP are associated with clear cell renal cell carcinoma risk in a Chinese population.PLoS One. 2014 Oct 16;9(10):e109285. doi: 10.1371/journal.pone.0109285. eCollection 2014.
379 Suppression of Angiogenesis by Targeting Cyclin-Dependent Kinase 7 in Human Umbilical Vein Endothelial Cells and Renal Cell Carcinoma: An In Vitro and In Vivo Study.Cells. 2019 Nov 19;8(11):1469. doi: 10.3390/cells8111469.
380 PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2-Targeting Therapy for Renal Cell Carcinoma.Cancer Res. 2017 Nov 15;77(22):6321-6329. doi: 10.1158/0008-5472.CAN-17-1589. Epub 2017 Sep 26.
381 SETD2 loss sensitizes cells to PI3K and AKT inhibition.Oncotarget. 2019 Jan 18;10(6):647-659. doi: 10.18632/oncotarget.26567. eCollection 2019 Jan 18.
382 PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway.Angiogenesis. 2019 Nov;22(4):507-519. doi: 10.1007/s10456-019-09675-z. Epub 2019 Jun 28.
383 Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth.Oncotarget. 2014 Feb 28;5(4):1004-13. doi: 10.18632/oncotarget.1681.
384 PLK1 promotes proliferation and suppresses apoptosis of renal cell carcinoma cells by phosphorylating MCM3.Cancer Gene Ther. 2020 Jun;27(6):412-423. doi: 10.1038/s41417-019-0094-x. Epub 2019 Jun 12.
385 Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma.Int J Oncol. 2016 May;48(5):1837-46. doi: 10.3892/ijo.2016.3440. Epub 2016 Mar 15.
386 Nivolumab-induced hypophysitis causing secondary adrenal insufficiency after transient ACTH elevation.Endocr J. 2019 Oct 28;66(10):937-941. doi: 10.1507/endocrj.EJ19-0076. Epub 2019 Jun 19.
387 Glutamine-phosphoribosylpyrophosphate amidotransferase (amidophosphoribosyltransferase, EC 2.4.2.14) activity in normal, differentiating, and neoplastic kidney.Cancer Res. 1979 Oct;39(10):3909-14.
388 The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling. Cell. 2005 Sep 23;122(6):835-47. doi: 10.1016/j.cell.2005.07.003.
389 Protein kinase C eta is associated with progression of renal cell carcinoma (RCC).Anticancer Res. 2003 Sep-Oct;23(5A):4001-6.
390 Down-regulation of PKC in renal cell carcinoma and its clinicopathological implications.J Biomed Sci. 2012 Apr 5;19(1):39. doi: 10.1186/1423-0127-19-39.
391 Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes.Clin Cancer Res. 2006 Dec 1;12(23):6937-45. doi: 10.1158/1078-0432.CCR-06-1268.
392 Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation.Clin Cancer Res. 2003 May;9(5):1721-7.
393 PTBP1 knockdown in renal cell carcinoma inhibits cell migration, invasion and angiogenesis in vitro and metastasis in vivo via the hypoxia inducible factor-1 pathway.Int J Oncol. 2018 May;52(5):1613-1622. doi: 10.3892/ijo.2018.4296. Epub 2018 Mar 2.
394 Prostaglandin E2 regulates renal cell carcinoma invasion through the EP4 receptor-Rap GTPase signal transduction pathway.J Biol Chem. 2011 Sep 30;286(39):33954-62. doi: 10.1074/jbc.M110.187344. Epub 2011 Aug 10.
395 Overexpression of cyclooxygenase-1 correlates with poor prognosis in renal cell carcinoma.Asian Pac J Cancer Prev. 2013;14(6):3729-34. doi: 10.7314/apjcp.2013.14.6.3729.
396 Significance of cyclooxygenase-2, prostaglandin E2 and CD133 levels in sunitinib-resistant renal cell carcinoma.Oncol Lett. 2019 Aug;18(2):1442-1450. doi: 10.3892/ol.2019.10442. Epub 2019 Jun 6.
397 Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo.Carcinogenesis. 2006 Jan;27(1):73-83. doi: 10.1093/carcin/bgi203. Epub 2005 Aug 4.
398 Kinomic profiling identifies focal adhesion kinase 1 as a therapeutic target in advanced clear cell renal cell carcinoma.Oncotarget. 2017 Apr 25;8(17):29220-29232. doi: 10.18632/oncotarget.16352.
399 SGK2 promotes renal cancer progression via enhancing ERK 1/2 and AKT phosphorylation.Eur Rev Med Pharmacol Sci. 2019 Apr;23(7):2756-2767. doi: 10.26355/eurrev_201904_17549.
400 Protein tyrosine phosphatase enhances proliferation by increasing -catenin nuclear expression in VHL-inactive human renal cell carcinoma cells.World J Urol. 2013 Dec;31(6):1547-54. doi: 10.1007/s00345-013-1077-4. Epub 2013 Apr 16.
401 Neuropeptide Y receptors in renal cell carcinomas and nephroblastomas.Int J Cancer. 2005 Jul 10;115(5):734-41. doi: 10.1002/ijc.20948.
402 DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma.Theranostics. 2019 Aug 14;9(21):6175-6190. doi: 10.7150/thno.35572. eCollection 2019.
403 MiR-204 inhibits the proliferation and invasion of renal cell carcinoma by inhibiting RAB22A expression.Oncol Rep. 2016 May;35(5):3000-8. doi: 10.3892/or.2016.4624. Epub 2016 Feb 16.
404 Regulation of receptor for activated C kinase 1 protein by the von Hippel-Lindau tumor suppressor in IGF-I-induced renal carcinoma cell invasiveness.Oncogene. 2011 Feb 3;30(5):535-47. doi: 10.1038/onc.2010.427. Epub 2010 Sep 27.
405 RIP1-dependent reactive oxygen species production executes artesunate-induced cell death in renal carcinoma Caki cells.Mol Cell Biochem. 2017 Nov;435(1-2):15-24. doi: 10.1007/s11010-017-3052-7. Epub 2017 May 2.
406 Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.Clin Cancer Res. 2005 May 1;11(9):3558-66. doi: 10.1158/1078-0432.CCR-04-1155.
407 HIF-1alpha mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma.J Cell Sci. 2003 Jun 1;116(Pt 11):2247-60. doi: 10.1242/jcs.00427. Epub 2003 Apr 15.
408 Identification of gene markers associated with metastasis in clear cell renal cell carcinoma.Oncol Lett. 2017 Jun;13(6):4755-4761. doi: 10.3892/ol.2017.6084. Epub 2017 Apr 24.
409 Upregulation of RICTOR gene transcription by the proinflammatory cytokines through NF-B pathway contributes to the metastasis of renal cell carcinoma.Tumour Biol. 2016 Apr;37(4):4457-66. doi: 10.1007/s13277-015-4296-z. Epub 2015 Oct 25.
410 A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma.Oncotarget. 2017 Sep 5;8(62):104928-104945. doi: 10.18632/oncotarget.20650. eCollection 2017 Dec 1.
411 Acid, basic, and neutral peptidases present different profiles in chromophobe renal cell carcinoma and in oncocytoma.Am J Physiol Renal Physiol. 2008 Apr;294(4):F850-8. doi: 10.1152/ajprenal.00469.2007. Epub 2008 Jan 23.
412 Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.Oncogene. 2002 May 2;21(19):3020-8. doi: 10.1038/sj.onc.1205421.
413 MiR-199a targeting ROCK1 to affect kidney cell proliferation, invasion and apoptosis.Artif Cells Nanomed Biotechnol. 2018 Dec;46(8):1920-1925. doi: 10.1080/21691401.2017.1396224. Epub 2017 Nov 13.
414 Expression of Ror2 mediates invasive phenotypes in renal cell carcinoma.PLoS One. 2014 Dec 26;9(12):e116101. doi: 10.1371/journal.pone.0116101. eCollection 2014.
415 Ribosomal s6 protein kinase 4: a prognostic factor for renal cell carcinoma.Br J Cancer. 2013 Sep 3;109(5):1137-46. doi: 10.1038/bjc.2013.463. Epub 2013 Aug 13.
416 Remodeling and spacing factor 1 overexpression is associated with poor prognosis in renal cell carcinoma. Oncol Lett. 2018 Mar;15(3):3852-3857.
417 Prognostic significance of vitamin D receptor and retinoid X receptor expression in renal cell carcinoma.J Urol. 2007 Oct;178(4 Pt 1):1497-503. doi: 10.1016/j.juro.2007.05.119. Epub 2007 Aug 16.
418 Proteins S100A8 and S100A9 are potential biomarkers for renal cell carcinoma in the early stages: results from a proteomic study integrated with bioinformatics analysis.Mol Med Rep. 2015 Jun;11(6):4093-100. doi: 10.3892/mmr.2015.3321. Epub 2015 Feb 9.
419 Immunogenic properties of renal cell carcinoma and the pathogenesis of osteolytic bone metastases.Int J Oncol. 2009 May;34(5):1387-93.
420 Somatic Bi-allelic Loss of TSC Genes in Eosinophilic Solid and Cystic Renal Cell Carcinoma.Eur Urol. 2018 Oct;74(4):483-486. doi: 10.1016/j.eururo.2018.06.007. Epub 2018 Jun 23.
421 Expression of Genes Involved in Porphyrin Biosynthesis Pathway in the Human Renal Cell Carcinoma.J Fluoresc. 2015 Sep;25(5):1363-9. doi: 10.1007/s10895-015-1626-x. Epub 2015 Aug 6.
422 Upregulation of miR-489-3p and miR-630 inhibits oxaliplatin uptake in renal cell carcinoma by targeting OCT2.Acta Pharm Sin B. 2019 Sep;9(5):1008-1020. doi: 10.1016/j.apsb.2019.01.002. Epub 2019 Jan 8.
423 The prospect of precision therapy for renal cell carcinoma.Cancer Treat Rev. 2016 Sep;49:37-44. doi: 10.1016/j.ctrv.2016.07.003. Epub 2016 Jul 12.
424 Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma.Epigenetics. 2012 Mar;7(3):278-90. doi: 10.4161/epi.7.3.19103.
425 CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior.Mol Cancer. 2013 Dec 21;12:169. doi: 10.1186/1476-4598-12-169.
426 Knockdown of sodium-calcium exchanger 1 induces epithelial-to-mesenchymal transition in kidney epithelial cells. J Biol Chem. 2017 Jul 7;292(27):11388-11399.
427 Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.Theranostics. 2019 Oct 22;9(26):8377-8391. doi: 10.7150/thno.37628. eCollection 2019.
428 Suppression of SOCS3 enhances TRAIL-induced cell growth inhibition through the upregulation of DR4 expression in renal cell carcinoma cells.Oncotarget. 2018 Aug 3;9(60):31697-31708. doi: 10.18632/oncotarget.25851. eCollection 2018 Aug 3.
429 The Impact Of Succinate Dehydrogenase Gene (SDH) Mutations In Renal Cell Carcinoma (RCC): A Systematic Review.Onco Targets Ther. 2019 Sep 26;12:7929-7940. doi: 10.2147/OTT.S207460. eCollection 2019.
430 Matriptase and MET are prominently expressed at the site of bone metastasis in renal cell carcinoma: immunohistochemical analysis.Hum Cell. 2015 Jan;28(1):44-50. doi: 10.1007/s13577-014-0101-3. Epub 2014 Sep 4.
431 Impact of Sulfatase-2 on cancer progression and prognosis in patients with renal cell carcinoma.Cancer Sci. 2016 Nov;107(11):1632-1641. doi: 10.1111/cas.13074.
432 Molecular analysis of a familial case of renal cell cancer and a t(3;6)(q12;q15).Genes Chromosomes Cancer. 2001 May;31(1):23-32. doi: 10.1002/gcc.1114.
433 The F-prostaglandin receptor is a novel marker for tumor endothelial cells in renal cell carcinoma.Pathol Int. 2013 Jan;63(1):37-44. doi: 10.1111/pin.12031.
434 Dual Inhibition of Angiopoietin-TIE2 and MET Alters the Tumor Microenvironment and Prolongs Survival in a Metastatic Model of Renal Cell Carcinoma.Mol Cancer Ther. 2020 Jan;19(1):147-156. doi: 10.1158/1535-7163.MCT-18-1202. Epub 2019 Oct 3.
435 Emerging immunotherapeutic strategies targeting telomerases in genitourinary tumors.Crit Rev Oncol Hematol. 2018 Nov;131:1-6. doi: 10.1016/j.critrevonc.2018.07.008. Epub 2018 Aug 1.
436 Over-expression of telomere binding factors (TRF1 & TRF2) in renal cell carcinoma and their inhibition by using SiRNA induce apoptosis, reduce cell proliferation and migration invitro.PLoS One. 2015 Mar 2;10(3):e0115651. doi: 10.1371/journal.pone.0115651. eCollection 2015.
437 Identification of novel epigenetic markers for clear cell renal cell carcinoma.J Urol. 2008 Sep;180(3):1126-30. doi: 10.1016/j.juro.2008.04.137. Epub 2008 Jul 18.
438 TGF-alpha as a candidate tumor antigen for renal cell carcinomas.Cancer Immunol Immunother. 2009 Aug;58(8):1207-18. doi: 10.1007/s00262-008-0630-2. Epub 2008 Dec 4.
439 Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression.J Biol Chem. 2001 Nov 9;276(45):41889-97. doi: 10.1074/jbc.M105049200. Epub 2001 Sep 10.
440 Identification of receptor genes in renal cell carcinoma associated with angiogenesis by differential hybridization technique.Biochem Biophys Res Commun. 1999 Apr 21;257(3):855-9. doi: 10.1006/bbrc.1999.0465.
441 Differential expression of thymosin genes in human tumors and in the developing human kidney.Int J Cancer. 1991 Jul 9;48(5):672-7. doi: 10.1002/ijc.2910480507.
442 Enhancement of death receptor 4-mediated apoptosis and cytotoxicity in renal cell carcinoma cells by anisomycin.Anticancer Drugs. 2017 Feb;28(2):180-186. doi: 10.1097/CAD.0000000000000450.
443 Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinoma.FEBS J. 2015 Dec;282(24):4747-4765. doi: 10.1111/febs.13532. Epub 2015 Oct 18.
444 Detection of the TNFSF members BAFF, APRIL, TWEAK and their receptors in normal kidney and renal cell carcinomas.Anal Cell Pathol (Amst). 2011;34(1-2):49-60. doi: 10.3233/ACP-2011-0001.
445 Suppression of renal cell carcinoma growth in vivo by forced expression of vascular endothelial growth inhibitor.Int J Oncol. 2013 May;42(5):1664-73. doi: 10.3892/ijo.2013.1877. Epub 2013 Mar 29.
446 Preclinical development of T-cell receptor-engineered T-cell therapy targeting the 5T4 tumor antigen on renal cell carcinoma.Cancer Immunol Immunother. 2019 Dec;68(12):1979-1993. doi: 10.1007/s00262-019-02419-4. Epub 2019 Nov 4.
447 Expression of Translationally Controlled Tumor Protein in Human Kidney and in Renal Cell Carcinoma.Biomed Res Int. 2015;2015:730390. doi: 10.1155/2015/730390. Epub 2015 Sep 3.
448 Depletion of the triggering receptor expressed on myeloid cells 2 inhibits progression of renal cell carcinoma via regulating related protein expression and PTEN-PI3K/Akt pathway.Int J Oncol. 2016 Dec;49(6):2498-2506. doi: 10.3892/ijo.2016.3740. Epub 2016 Oct 19.
449 TRIM59 is a key regulator of growth and migration inrenal cell carcinoma.Cell Mol Biol (Noisy-le-grand). 2017 May 20;63(5):68-74. doi: 10.14715/cmb/2017.63.5.13.
450 Splicing variant of Cdc42 interacting protein-4 disrupts beta-catenin-mediated cell-cell adhesion: expression and function in renal cell carcinoma.Biochem Biophys Res Commun. 2006 Jan 27;339(4):1083-8. doi: 10.1016/j.bbrc.2005.11.117. Epub 2005 Dec 5.
451 Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma.FEBS J. 2007 Dec;274(24):6365-77. doi: 10.1111/j.1742-4658.2007.06159.x. Epub 2007 Nov 15.
452 CircRNA cRAPGEF5 inhibits the growth and metastasis of renal cell carcinoma via the miR-27a-3p/TXNIP pathway.Cancer Lett. 2020 Jan 28;469:68-77. doi: 10.1016/j.canlet.2019.10.017. Epub 2019 Oct 17.
453 UBE2T promotes proliferation and regulates PI3K/Akt signaling in renal cell carcinoma.Mol Med Rep. 2019 Aug;20(2):1212-1220. doi: 10.3892/mmr.2019.10322. Epub 2019 Jun 3.
454 Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma.J Transl Med. 2009 Oct 26;7:90. doi: 10.1186/1479-5876-7-90.
455 Vascular endothelial growth factor-B and vascular endothelial growth factor-C expression in renal cell carcinomas: regulation by the von Hippel-Lindau gene and hypoxia.Cancer Res. 2001 Apr 1;61(7):3206-11.
456 VEGFC acts as a double-edged sword in renal cell carcinoma aggressiveness.Theranostics. 2019 Jan 21;9(3):661-675. doi: 10.7150/thno.27794. eCollection 2019.
457 Serum soluble B7-H4 is a prognostic marker for patients with non-metastatic clear cell renal cell carcinoma.PLoS One. 2018 Jul 25;13(7):e0199719. doi: 10.1371/journal.pone.0199719. eCollection 2018.
458 Alterations of the WNT7A gene in clear cell renal cell carcinomas.PLoS One. 2012;7(10):e47012. doi: 10.1371/journal.pone.0047012. Epub 2012 Oct 8.
459 Potential biological process of X-linked inhibitor of apoptosis protein in renal cell carcinoma based upon differential protein expression analysis.Oncol Lett. 2018 Jan;15(1):821-832. doi: 10.3892/ol.2017.7383. Epub 2017 Nov 9.
460 Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types.FEBS J. 2010 Nov;277(21):4519-29. doi: 10.1111/j.1742-4658.2010.07861.x. Epub 2010 Sep 30.
461 Germline genetic variants in somatically significantly mutated genes in tumors are associated with renal cell carcinoma risk and outcome.Carcinogenesis. 2018 May 28;39(6):752-757. doi: 10.1093/carcin/bgy021.
462 Clusterin promotes growth and invasion of clear cell renal carcinoma cell by upregulation of S100A4 expression.Cancer Biomark. 2018;21(4):915-923. doi: 10.3233/CBM-171018.
463 Endostatin Effects on Tumor Cells and Vascular Network of Human Renal Cell Carcinoma Implanted on Chick Embryo Chorioallantoic Membrane.Anticancer Res. 2015 Dec;35(12):6521-8.
464 A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma.BMC Cancer. 2017 Jan 4;17(1):9. doi: 10.1186/s12885-016-3030-6.
465 Induction of the connexin 32 gene by epigallocatechin-3-gallate potentiates vinblastine-induced cytotoxicity in human renal carcinoma cells.Chemotherapy. 2013;59(3):192-9. doi: 10.1159/000354715. Epub 2013 Dec 3.
466 HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.Int J Cancer. 2008 Dec 1;123(11):2616-25. doi: 10.1002/ijc.23823.
467 Linking Binary Gene Relationships to Drivers of Renal Cell Carcinoma Reveals Convergent Function in Alternate Tumor Progression Paths.Sci Rep. 2019 Feb 27;9(1):2899. doi: 10.1038/s41598-019-39875-y.
468 Transglutaminase 2 Promotes Autophagy by LC3 Induction through p53 Depletion in Cancer Cell.Biomol Ther (Seoul). 2019 Jan 1;27(1):34-40. doi: 10.4062/biomolther.2018.140.
469 Involvement of ABC transporters in chemosensitivity of human renal cell carcinoma, and regulation of MRP2 expression by conjugated bilirubin.Anticancer Res. 2005 Jul-Aug;25(4):2729-35.
470 Downregulation of ABCD1 in human renal cell carcinoma.Int J Biol Markers. 2009 Jul-Sep;24(3):171-8. doi: 10.1177/172460080902400307.
471 Structure of the human receptor tyrosine phosphatase gamma gene (PTPRG) and relation to the familial RCC t(3;8) chromosome translocation.Genomics. 1996 Mar 1;32(2):225-35. doi: 10.1006/geno.1996.0109.
472 Coordinate expression of nuclear and mitochondrial genes involved in energy production in carcinoma and oncocytoma.Biochim Biophys Acta. 1996 Aug 23;1316(3):203-9. doi: 10.1016/0925-4439(96)00026-9.
473 Differential expression of facilitative glucose transporters in normal and tumour kidney tissues.BJU Int. 2007 May;99(5):1143-9. doi: 10.1111/j.1464-410X.2007.06765.x.
474 Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI.J Biol Chem. 2020 Mar 27;295(13):4065-4078. doi: 10.1074/jbc.RA119.009827. Epub 2019 Nov 5.
475 Association between ZIP10 gene expression and tumor aggressiveness in renal cell carcinoma.Gene. 2014 Nov 15;552(1):195-8. doi: 10.1016/j.gene.2014.09.010. Epub 2014 Sep 6.
476 Zinc transporter genes and urological cancers: integrated analysis suggests a role for ZIP11 in bladder cancer.Tumour Biol. 2015 Sep;36(10):7431-7. doi: 10.1007/s13277-015-3459-2. Epub 2015 Apr 23.
477 Localization of NBC-1 variants in human kidney and renal cell carcinoma.Biochem Biophys Res Commun. 2003 Oct 31;310(4):1213-8. doi: 10.1016/j.bbrc.2003.09.147.
478 Acetyl-CoA synthetase 2 enhances tumorigenesis and is indicative of a poor prognosis for patients with renal cell carcinoma.Urol Oncol. 2018 May;36(5):243.e9-243.e20. doi: 10.1016/j.urolonc.2018.01.013. Epub 2018 Mar 2.
479 The alterations in alcohol dehydrogenase and aldehyde dehydrogenase activities in the sera of patients with renal cell carcinoma.Adv Med Sci. 2018 Mar;63(1):1-4. doi: 10.1016/j.advms.2017.05.001. Epub 2017 Jul 28.
480 Aldehyde dehydrogenase 1 identifies cells with cancer stem cell-like properties in a human renal cell carcinoma cell line.PLoS One. 2013 Oct 8;8(10):e75463. doi: 10.1371/journal.pone.0075463. eCollection 2013.
481 Association between cytochrome P450 1A1 (CYP1A1) gene polymorphisms and the risk of renal cell carcinoma: a meta-analysis.Sci Rep. 2015 Jan 29;5:8108. doi: 10.1038/srep08108.
482 Expression of lactate dehydrogenase C correlates with poor prognosis in renal cell carcinoma.Tumour Biol. 2017 Mar;39(3):1010428317695968. doi: 10.1177/1010428317695968.
483 Potential biomarkers for the therapeutic efficacy of sorafenib, sunitinib and everolimus.Oncol Rep. 2017 Jan;37(1):227-234. doi: 10.3892/or.2016.5232. Epub 2016 Nov 8.
484 Human agmatinase is diminished in the clear cell type of renal cell carcinoma.Int J Cancer. 2004 Jan 20;108(3):342-7. doi: 10.1002/ijc.11459.
485 The Preoperative Predictive Factors for Pathological T3a Upstaging of Clinical T1 Renal Cell Carcinoma.Diagnostics (Basel). 2019 Jul 15;9(3):76. doi: 10.3390/diagnostics9030076.
486 Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux.Mol Cell Biol. 2007 Oct;27(20):7345-53. doi: 10.1128/MCB.02201-06. Epub 2007 Aug 6.
487 In vivo gene expression profile analysis of metallothionein in renal cell carcinoma.Cancer Lett. 2000 Nov 28;160(2):133-40. doi: 10.1016/s0304-3835(00)00534-6.
488 Association of GSTT1 non-null and NAT1 slow/rapid genotypes with von Hippel-Lindau tumour suppressor gene transversions in sporadic renal cell carcinoma.Pharmacogenetics. 2001 Aug;11(6):521-35. doi: 10.1097/00008571-200108000-00007.
489 Nicotinamide N-Methyltransferase and Its Precursor Substrate Methionine Directly and Indirectly Control Malignant Metabolism During Progression of Renal Cell Carcinoma.Anticancer Res. 2019 Oct;39(10):5427-5436. doi: 10.21873/anticanres.13736.
490 Expression parameters of the metabolic pathway genes pyruvate dehydrogenase kinase-1 (PDK-1) and DJ-1/PARK7 in renal cell carcinoma (RCC).World J Urol. 2013 Oct;31(5):1191-6. doi: 10.1007/s00345-012-0874-5. Epub 2012 Apr 29.
491 Imaging of renal cell carcinoma in patients with acquired cystic disease of the kidney: comparison (11)C-choline and FDG PET/CT with dynamic contrast-enhanced CT.Jpn J Radiol. 2019 Feb;37(2):165-177. doi: 10.1007/s11604-018-0789-1. Epub 2018 Oct 30.
492 Differential aminoacylase expression in neuroblastoma.Int J Cancer. 2011 Sep 15;129(6):1322-30. doi: 10.1002/ijc.25798. Epub 2011 Apr 1.
493 The Adiponectin-AdipoR1 Axis Mediates Tumor Progression and Tyrosine Kinase Inhibitor Resistance in Metastatic Renal Cell Carcinoma.Neoplasia. 2019 Sep;21(9):921-931. doi: 10.1016/j.neo.2019.07.004. Epub 2019 Aug 8.
494 Role of APLP2 in the prognosis and clinicopathology of renal cell carcinoma.Oncol Lett. 2019 Jan;17(1):508-513. doi: 10.3892/ol.2018.9577. Epub 2018 Oct 15.
495 Analysis of the characteristics of chemotherapy-resistant renal cell carcinomas based on global transcriptional analysis of their tissues and cell lines.PLoS One. 2019 Nov 27;14(11):e0225721. doi: 10.1371/journal.pone.0225721. eCollection 2019.
496 Pharmacologic Targeting of Hypoxia-Inducible Factors.Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:379-403. doi: 10.1146/annurev-pharmtox-010818-021637.
497 CA8 promotes RCC proliferation and migration though its expression level is lower in tumor compared to adjacent normal tissue.Biomed Pharmacother. 2020 Jan;121:109578. doi: 10.1016/j.biopha.2019.109578. Epub 2019 Nov 10.
498 Nephroblastoma overexpressed gene expression and its prognostic implications of clinical outcomes in renal cell carcinoma patients.Cancer Biomark. 2017 Sep 7;20(3):241-246. doi: 10.3233/CBM-170017.
499 The metastasis suppressor CD82/KAI1 regulates cell migration and invasion via inhibiting TGF- 1/Smad signaling in renal cell carcinoma.Oncotarget. 2017 May 23;8(31):51559-51568. doi: 10.18632/oncotarget.18086. eCollection 2017 Aug 1.
500 VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration.Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1931-6. doi: 10.1073/pnas.1011777108. Epub 2011 Jan 13.
501 Knockdown of CHCHD2 inhibits migration and angiogenesis of human renal cell carcinoma: A potential molecular marker for treatment of RCC.Oncol Lett. 2019 Jan;17(1):765-772. doi: 10.3892/ol.2018.9686. Epub 2018 Nov 12.
502 M2 Macrophage Marker Chitinase 3-Like 2 (CHI3L2) Associates With Progression of Conventional Renal Cell Carcinoma.Anticancer Res. 2019 Dec;39(12):6939-6943. doi: 10.21873/anticanres.13915.
503 CMTM5 inhibits renal cancer cell growth through inducing cell-cycle arrest and apoptosis.Oncol Lett. 2017 Aug;14(2):1536-1542. doi: 10.3892/ol.2017.6350. Epub 2017 Jun 8.
504 Cyclin D1 and p57 expression in relation to clinicopathological characteristics and overall survival in patients with renal cell carcinoma.J BUON. 2019 Jan-Feb;24(1):301-309.
505 miR-26 suppresses renal cell cancer via down-regulating coronin-3.Mol Cell Biochem. 2020 Jan;463(1-2):137-146. doi: 10.1007/s11010-019-03636-2. Epub 2019 Oct 8.
506 Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability.Oncogenesis. 2019 Jan 9;8(1):4. doi: 10.1038/s41389-018-0110-2.
507 Tumoural CXCL16 expression is a novel prognostic marker of longer survival times in renal cell cancer patients.Eur J Cancer. 2009 Feb;45(3):478-89. doi: 10.1016/j.ejca.2008.10.023. Epub 2008 Dec 11.
508 Human beta-defensin-1, a potential chromosome 8p tumor suppressor: control of transcription and induction of apoptosis in renal cell carcinoma.Cancer Res. 2006 Sep 1;66(17):8542-9. doi: 10.1158/0008-5472.CAN-06-0294.
509 Estrogen receptor-binding fragment-associated gene 9 expression and its clinical significance in human testicular cancer.Int J Urol. 2009 Mar;16(3):329-32. doi: 10.1111/j.1442-2042.2008.02233.x. Epub 2009 Jan 20.
510 Genetic Underpinnings of Renal Cell Carcinoma With Leiomyomatous Stroma.Am J Surg Pathol. 2019 Aug;43(8):1135-1144. doi: 10.1097/PAS.0000000000001255.
511 A novel protein is lower expressed in renal cell carcinoma.Int J Mol Sci. 2014 Apr 29;15(5):7398-408. doi: 10.3390/ijms15057398.
512 Methylation-associated silencing of TU3A in human cancers.Int J Oncol. 2008 Oct;33(4):893-9.
513 miR-29b and miR-198 overexpression in CD8+ T cells of renal cell carcinoma patients down-modulates JAK3 and MCL-1 leading to immune dysfunction.J Transl Med. 2016 Apr 11;14:84. doi: 10.1186/s12967-016-0841-9.
514 MicroRNA-125a suppresses cell migration, invasion, and regulates hyaluronic acid synthase 1 expression by targeting signal transducers and activators of transcription 3 in renal cell carcinoma cells.J Cell Biochem. 2019 Feb;120(2):1894-1902. doi: 10.1002/jcb.27503. Epub 2018 Sep 6.
515 Diagnostic role of kidney injury molecule-1 in renal cell carcinoma.Int Urol Nephrol. 2019 Nov;51(11):1893-1902. doi: 10.1007/s11255-019-02231-0. Epub 2019 Aug 5.
516 HepaCAM Regulates Warburg Effect of Renal Cell Carcinoma via HIF-1/NF-B Signaling Pathway.Urology. 2019 May;127:61-67. doi: 10.1016/j.urology.2018.11.033. Epub 2018 Dec 4.
517 Inhibitor of growth 4 inhibits cell proliferation, migration, and induces apoptosis of renal cell carcinoma cells.J Cell Biochem. 2019 Apr;120(4):6709-6717. doi: 10.1002/jcb.27967. Epub 2018 Nov 2.
518 Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.Clin Cancer Res. 2018 Dec 15;24(24):6433-6446. doi: 10.1158/1078-0432.CCR-18-1727. Epub 2018 Aug 14.
519 Germline and somatic DNA methylation and epigenetic regulation of KILLIN in renal cell carcinoma.Genes Chromosomes Cancer. 2011 Aug;50(8):654-61. doi: 10.1002/gcc.20887. Epub 2011 May 16.
520 Karyopherin Alpha 2 Is an Adverse Prognostic Factor in Clear-Cell and Papillary Renal-Cell Carcinoma.Clin Genitourin Cancer. 2019 Feb;17(1):e167-e175. doi: 10.1016/j.clgc.2018.10.008. Epub 2018 Oct 23.
521 MicroRNA-200b is downregulated and suppresses metastasis by targeting LAMA4 in renal cell carcinoma.EBioMedicine. 2019 Jun;44:439-451. doi: 10.1016/j.ebiom.2019.05.041. Epub 2019 May 23.
522 Characterization of the expression of LAT1 as a prognostic indicator and a therapeutic target in renal cell carcinoma.Sci Rep. 2019 Nov 20;9(1):16776. doi: 10.1038/s41598-019-53397-7.
523 High expression of MICA in human kidney cancer tissue and renal cell carcinoma lines.Asian Pac J Cancer Prev. 2014;15(4):1715-7. doi: 10.7314/apjcp.2014.15.4.1715.
524 HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma.Onco Targets Ther. 2018 Aug 1;11:4501-4510. doi: 10.2147/OTT.S167197. eCollection 2018.
525 Mitochondrial pyruvate carrier 1 functions as a tumor suppressor and predicts the prognosis of human renal cell carcinoma.Lab Invest. 2019 Feb;99(2):191-199. doi: 10.1038/s41374-018-0138-0. Epub 2018 Oct 5.
526 DNA methylation of metallothionein genes is associated with the clinical features of renal cell carcinoma.Oncol Rep. 2019 Jun;41(6):3535-3544. doi: 10.3892/or.2019.7109. Epub 2019 Apr 10.
527 NDNF inhibits the migration and invasion of human renal cancer cells through epithelial-mesenchymal transition.Oncol Lett. 2019 Mar;17(3):2969-2975. doi: 10.3892/ol.2019.9937. Epub 2019 Jan 15.
528 Suppression of GLTSCR2 expression in renal cell carcinomas.Pathol Res Pract. 2016 Feb;212(2):120-4. doi: 10.1016/j.prp.2015.12.005. Epub 2015 Dec 14.
529 Suppressed OGT expression inhibits cell proliferation and modulates EGFR expression in renal cell carcinoma.Cancer Manag Res. 2019 Mar 19;11:2215-2223. doi: 10.2147/CMAR.S190642. eCollection 2019.
530 Downregulation of PDCD4 by miR-21 suppresses tumor transformation and proliferation in a nude mouse renal cancer model.Oncol Lett. 2017 Sep;14(3):3371-3378. doi: 10.3892/ol.2017.6605. Epub 2017 Jul 18.
531 MiR-23a-3p acts as an oncogene and potential prognostic biomarker by targeting PNRC2 in RCC.Biomed Pharmacother. 2019 Feb;110:656-666. doi: 10.1016/j.biopha.2018.11.065. Epub 2018 Dec 12.
532 Reference genes for gene expression analysis by real-time reverse transcription polymerase chain reaction of renal cell carcinoma.Diagn Mol Pathol. 2011 Dec;20(4):212-7. doi: 10.1097/PDM.0b013e318212e0a9.
533 RBM10-TFE3 renal cell carcinoma characterised by paracentric inversion with consistent closely split signals in break-apart fluorescence in-situ hybridisation: study of 10 cases and a literature review.Histopathology. 2019 Aug;75(2):254-265. doi: 10.1111/his.13866. Epub 2019 Jun 25.
534 RIN1 promotes renal cell carcinoma malignancy by activating EGFR signaling through Rab25.Cancer Sci. 2017 Aug;108(8):1620-1627. doi: 10.1111/cas.13297. Epub 2017 Jul 3.
535 Inactivation of SAG or ROC1 E3 Ligase Inhibits Growth and Survival of Renal Cell Carcinoma Cells: Effect of BIM.Transl Oncol. 2019 Jun;12(6):810-818. doi: 10.1016/j.tranon.2019.03.002. Epub 2019 Apr 4.
536 von Hippel-Lindau mutants in renal cell carcinoma are regulated by increased expression of RSUME.Cell Death Dis. 2019 Mar 19;10(4):266. doi: 10.1038/s41419-019-1507-3.
537 LncRNA SCAMP1 regulates ZEB1/JUN and autophagy to promote pediatric renal cell carcinoma under oxidative stress via miR-429.Biomed Pharmacother. 2019 Dec;120:109460. doi: 10.1016/j.biopha.2019.109460. Epub 2019 Sep 21.
538 Vimentin Overexpressions Induced by Cell Hypoxia Promote Vasculogenic Mimicry by Renal Cell Carcinoma Cells.Biomed Res Int. 2019 Jul 21;2019:7259691. doi: 10.1155/2019/7259691. eCollection 2019.
539 SFRP1 CpG island methylation locus is associated with renal cell cancer susceptibility and disease recurrence.Epigenetics. 2012 May;7(5):447-57. doi: 10.4161/epi.19614. Epub 2012 May 1.
540 Secreted frizzled-related protein-5 is epigenetically downregulated and functions as a tumor suppressor in kidney cancer.Int J Cancer. 2011 Feb 1;128(3):541-50. doi: 10.1002/ijc.25357.
541 UCA1 promotes cell proliferation and invasion and inhibits apoptosis through regulation of the miR129-SOX4 pathway in renal cell carcinoma.Onco Targets Ther. 2018 May 1;11:2475-2487. doi: 10.2147/OTT.S160192. eCollection 2018.
542 LINC00961 restrains cancer progression via modulating epithelial-mesenchymal transition in renal cell carcinoma.J Cell Physiol. 2019 May;234(5):7257-7265. doi: 10.1002/jcp.27483. Epub 2018 Oct 26.
543 The Role of Serine Peptidase Inhibitor Kazal Type 13 (SPINK13) as a Clinicopathological and Prognostic Biomarker in Patients with Clear Cell Renal Cell Carcinoma.Med Sci Monit. 2019 Dec 11;25:9458-9470. doi: 10.12659/MSM.917754.
544 Dysregulated HAI-2 Plays an Important Role in Renal Cell Carcinoma Bone Metastasis through Ligand-Dependent MET Phosphorylation.Cancers (Basel). 2018 Jun 8;10(6):190. doi: 10.3390/cancers10060190.
545 Standardized report template for indeterminate renal masses at CT and MRI: a collaborative product of the SAR Disease-Focused Panel on Renal Cell Carcinoma.Abdom Radiol (NY). 2019 Apr;44(4):1423-1429. doi: 10.1007/s00261-018-1851-2.
546 Syntaxin 6: A novel predictive and prognostic biomarker in papillary renal cell carcinoma.Sci Rep. 2019 Feb 28;9(1):3146. doi: 10.1038/s41598-019-39305-z.
547 MicroRNA-21 functions as an oncogene and promotes cell proliferation and invasion via TIMP3 in renal cancer.Eur Rev Med Pharmacol Sci. 2017 Oct;21(20):4566-4576.
548 TNIP1 Inhibits Proliferation And Promotes Apoptosis In Clear Cell Renal Carcinoma Through Targeting C/Ebp.Onco Targets Ther. 2019 Nov 18;12:9861-9871. doi: 10.2147/OTT.S216138. eCollection 2019.
549 TRIB3 Promotes the Proliferation and Invasion of Renal Cell Carcinoma Cells via Activating MAPK Signaling Pathway.Int J Biol Sci. 2019 Jan 1;15(3):587-597. doi: 10.7150/ijbs.29737. eCollection 2019.
550 HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma.Oncotarget. 2017 May 19;8(41):69559-69576. doi: 10.18632/oncotarget.18012. eCollection 2017 Sep 19.
551 Autoantibody against arrestin-1 as a potential biomarker of renal cell carcinoma.Biochimie. 2019 Feb;157:26-37. doi: 10.1016/j.biochi.2018.10.019. Epub 2018 Oct 30.
552 Association between ACYP2 polymorphisms and the risk of renal cell cancer.Mol Genet Genomic Med. 2019 Nov;7(11):e966. doi: 10.1002/mgg3.966. Epub 2019 Sep 5.
553 High expression of fructose-bisphosphate aldolaseA induces progression of renal cell carcinoma.Oncol Rep. 2018 Jun;39(6):2996-3006. doi: 10.3892/or.2018.6378. Epub 2018 Apr 18.
554 Clinical Relevance of Gene Copy Number Variation in Metastatic Clear Cell Renal Cell Carcinoma.Clin Genitourin Cancer. 2018 Aug;16(4):e795-e805. doi: 10.1016/j.clgc.2018.02.013. Epub 2018 Feb 23.
555 ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation.Am J Cancer Res. 2018 Jan 1;8(1):132-143. eCollection 2018.
556 Hypoxia-regulated lncRNA CRPAT4 promotes cell migration via regulating AVL9 in clear cell renal cell carcinomas.Onco Targets Ther. 2018 Aug 3;11:4537-4545. doi: 10.2147/OTT.S169155. eCollection 2018.
557 CAV2 promotes the growth of renal cell carcinoma through the EGFR/PI3K/Akt pathway.Onco Targets Ther. 2018 Sep 25;11:6209-6216. doi: 10.2147/OTT.S172803. eCollection 2018.
558 Identification of a novel lncRNA induced by the nephrotoxin ochratoxin A and expressed in human renal tumor tissue.Cell Mol Life Sci. 2018 Jun;75(12):2241-2256. doi: 10.1007/s00018-017-2731-6. Epub 2017 Dec 27.
559 CD151 promotes cell metastasis via activating TGF-1/Smad signaling in renal cell carcinoma.Oncotarget. 2018 Jan 8;9(17):13313-13323. doi: 10.18632/oncotarget.24028. eCollection 2018 Mar 2.
560 Expression of cold-inducible RNA-binding protein (CIRP) in renal cell carcinoma and the effect of CIRP downregulation cell proliferation and chemosensitivity to gemcitabine.Oncol Lett. 2018 May;15(5):7611-7616. doi: 10.3892/ol.2018.8338. Epub 2018 Mar 23.
561 CNPY2 promoted the proliferation of renal cell carcinoma cells and increased the expression of TP53.Biochem Biophys Res Commun. 2017 Apr 1;485(2):267-271. doi: 10.1016/j.bbrc.2017.02.095. Epub 2017 Feb 21.
562 Novel insights into biomarkers associated with renal cell carcinoma.Oncol Lett. 2018 Jul;16(1):83-90. doi: 10.3892/ol.2018.8665. Epub 2018 May 8.
563 RNAa and Vector-Mediated Overexpression of DIRAS1 Suppresses Tumor Growth and Migration in Renal Cell Carcinoma.Mol Ther Nucleic Acids. 2018 Sep 7;12:845-853. doi: 10.1016/j.omtn.2018.07.019. Epub 2018 Aug 8.
564 Three vasoactive peptides, endothelin-1, adrenomedullin and urotensin-II, in human tumour cell lines of different origin: expression and effects on proliferation.Clin Sci (Lond). 2002 Aug;103 Suppl 48:35S-38S. doi: 10.1042/CS103S035S.
565 High eukaryotic translation elongation factor 1 alpha 1 expression promotes proliferation and predicts poor prognosis in clear cell renal cell carcinoma.Neoplasma. 2020 Jan;67(1):78-84. doi: 10.4149/neo_2019_190224N158. Epub 2019 Nov 26.
566 Clinical validation of serum endocan (ESM-1) as a potential biomarker in patients with renal cell carcinoma.Oncotarget. 2017 Dec 10;9(1):662-667. doi: 10.18632/oncotarget.23087. eCollection 2018 Jan 2.
567 The Expression Patterns of FAM83H and PANX2 Are Associated With Shorter Survival of Clear Cell Renal Cell Carcinoma Patients.Front Oncol. 2019 Jan 22;9:14. doi: 10.3389/fonc.2019.00014. eCollection 2019.
568 SIRT1 downregulated FGB expression to inhibit RCC tumorigenesis by destabilizing STAT3.Exp Cell Res. 2019 Sep 15;382(2):111466. doi: 10.1016/j.yexcr.2019.06.011. Epub 2019 Jun 12.
569 The Diagnostic Value of FNDC5/Irisin in Renal Cell Cancer.Int Braz J Urol. 2018 Jul-Aug;44(4):734-739. doi: 10.1590/S1677-5538.IBJU.2017.0404.
570 Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.PLoS One. 2018 Jun 13;13(6):e0197973. doi: 10.1371/journal.pone.0197973. eCollection 2018.
571 FOXK2 suppresses the malignant phenotype and induces apoptosis through inhibition of EGFR in clear-cell renal cell carcinoma.Int J Cancer. 2018 Jun 15;142(12):2543-2557. doi: 10.1002/ijc.31278. Epub 2018 Feb 14.
572 Knockdown of GA-binding protein subunit 1 inhibits cell proliferation via p21 induction in renal cell carcinoma.Int J Oncol. 2018 Aug;53(2):886-894. doi: 10.3892/ijo.2018.4411. Epub 2018 May 17.
573 Regulation of ferroptotic cancer cell death by GPX4. Cell. 2014 Jan 16;156(1-2):317-331.
574 miR-488 inhibits cell growth and metastasis in renal cell carcinoma by targeting HMGN5.Onco Targets Ther. 2018 Apr 18;11:2205-2216. doi: 10.2147/OTT.S156361. eCollection 2018.
575 Novel splicing in IGFN1 intron 15 and role of stable G-quadruplex in the regulation of splicing in renal cell carcinoma.PLoS One. 2018 Oct 18;13(10):e0205660. doi: 10.1371/journal.pone.0205660. eCollection 2018.
576 Kinesin Motor Protein KIFC1 Is a Target Protein of miR-338-3p and Is Associated With Poor Prognosis and Progression of Renal Cell Carcinoma.Oncol Res. 2018 Dec 27;27(1):125-137. doi: 10.3727/096504018X15213115046567. Epub 2018 Mar 21.
577 A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma.Nat Commun. 2019 Mar 11;10(1):1152. doi: 10.1038/s41467-019-09116-x.
578 Knockdown of LETM1 inhibits proliferation and metastasis of human renal cell carcinoma cells.Oncol Lett. 2018 Nov;16(5):6377-6382. doi: 10.3892/ol.2018.9449. Epub 2018 Sep 18.
579 The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma.Oncogene. 2019 Jan;38(1):60-72. doi: 10.1038/s41388-018-0413-y. Epub 2018 Aug 3.
580 MAGI1 mediates tumor metastasis through c-Myb/miR-520h/MAGI1 signaling pathway in renal cell carcinoma.Apoptosis. 2019 Dec;24(11-12):837-848. doi: 10.1007/s10495-019-01562-8.
581 -1,2-Mannosidase MAN1C1 Inhibits Proliferation and Invasion of Clear Cell Renal Cell Carcinoma.J Cancer. 2018 Nov 24;9(24):4618-4626. doi: 10.7150/jca.27673. eCollection 2018.
582 Ubiquitination of MAP1LC3B by pVHL is associated with autophagy and cell death in renal cell carcinoma.Cell Death Dis. 2019 Mar 22;10(4):279. doi: 10.1038/s41419-019-1520-6.
583 Expression of minichromosome maintenance genes in renal cell carcinoma.Cancer Manag Res. 2017 Nov 15;9:637-647. doi: 10.2147/CMAR.S146528. eCollection 2017.
584 MCM5 promotes tumour proliferation and correlates with the progression and prognosis of renal cell carcinoma.Int Urol Nephrol. 2019 Sep;51(9):1517-1526. doi: 10.1007/s11255-019-02169-3. Epub 2019 Jun 12.
585 MTA2 as a Potential Biomarker and Its Involvement in Metastatic Progression of Human Renal Cancer by miR-133b Targeting MMP-9.Cancers (Basel). 2019 Nov 23;11(12):1851. doi: 10.3390/cancers11121851.
586 MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance.Int J Cancer. 2017 May 15;140(10):2351-2363. doi: 10.1002/ijc.30651. Epub 2017 Feb 28.
587 Co-expression of Cancer Stem Cell Markers OCT4 and NANOG Predicts Poor Prognosis in Renal Cell Carcinomas.Sci Rep. 2018 Aug 6;8(1):11739. doi: 10.1038/s41598-018-30168-4.
588 Major Differences in Hypoxia Tolerance and P38 Regulation Among Different Renal Cells.Cell Physiol Biochem. 2018;46(4):1483-1492. doi: 10.1159/000489188. Epub 2018 Apr 19.
589 Knockdown of NSD2 Suppresses Renal Cell Carcinoma Metastasis by Inhibiting Epithelial-Mesenchymal Transition.Int J Med Sci. 2019 Sep 20;16(10):1404-1411. doi: 10.7150/ijms.36128. eCollection 2019.
590 A novel function of NUCB2 in promoting the development and invasion of renal cell carcinoma.Oncol Lett. 2018 Feb;15(2):2425-2430. doi: 10.3892/ol.2017.7563. Epub 2017 Dec 8.
591 Renal cell carcinoma suspected at time of organ donation 2008-2016: A report of the OPTN ad hoc Disease Transmission Advisory Committee Registry.Clin Transplant. 2019 Jul;33(7):e13597. doi: 10.1111/ctr.13597. Epub 2019 Jun 25.
592 NudCD1 affects renal cell carcinoma through regulating LIS1/Dynein signaling pathway.Am J Transl Res. 2018 Feb 15;10(2):519-524. eCollection 2018.
593 Modifiable risk factors to reduce renal cell carcinoma incidence: Insight from the PLCO trial.Urol Oncol. 2018 Jul;36(7):340.e1-340.e6. doi: 10.1016/j.urolonc.2018.04.011. Epub 2018 May 17.
594 The Clinical Value of PELP1 for Breast Cancer: A Comparison with Multiple Cancers and Analysis in Breast Cancer Subtypes.Cancer Res Treat. 2019 Apr;51(2):706-717. doi: 10.4143/crt.2018.316. Epub 2018 Aug 23.
595 Anticancer activity of Schiff base-Poloxamer P85 combination against kidney cancer.Int Urol Nephrol. 2018 Feb;50(2):247-255. doi: 10.1007/s11255-017-1782-9. Epub 2017 Dec 29.
596 PLIN3 is up-regulated and correlates with poor prognosis in clear cell renal cell carcinoma.Urol Oncol. 2018 Jul;36(7):343.e9-343.e19. doi: 10.1016/j.urolonc.2018.04.006.
597 Exploring the Natural Piericidins as Anti-Renal Cell Carcinoma Agents Targeting Peroxiredoxin 1.J Med Chem. 2019 Aug 8;62(15):7058-7069. doi: 10.1021/acs.jmedchem.9b00598. Epub 2019 Jul 25.
598 The clinical significance of PYCR1 expression in renal cell carcinoma.Medicine (Baltimore). 2019 Jul;98(28):e16384. doi: 10.1097/MD.0000000000016384.
599 miR-384 suppressed renal cell carcinoma cell proliferation and migration through targeting RAB23.J Cell Biochem. 2019 Feb;120(2):1420-1426. doi: 10.1002/jcb.27180. Epub 2018 Nov 2.
600 The expression and function of RASAL2 in renal cell carcinoma angiogenesis.Cell Death Dis. 2018 Aug 29;9(9):881. doi: 10.1038/s41419-018-0898-x.
601 RASSF6-mediated inhibition of Mcl-1 through JNK activation improves the anti-tumor effects of sorafenib in renal cell carcinoma.Cancer Lett. 2018 Sep 28;432:75-83. doi: 10.1016/j.canlet.2018.05.048. Epub 2018 Jun 1.
602 Prolonged survival of renal cancer patients is concomitant with a higher regucalcin gene expression in tumor tissues: Overexpression of regucalcin suppresses the growth of human renal cell carcinoma cells in vitro.Int J Oncol. 2019 Jan;54(1):188-198. doi: 10.3892/ijo.2018.4611. Epub 2018 Oct 30.
603 Combined Treatment with Valproic Acid and 5-Aza-2'-Deoxycytidine Synergistically Inhibits Human Clear Cell Renal Cell Carcinoma Growth and Migration.Med Sci Monit. 2018 Feb 19;24:1034-1043. doi: 10.12659/msm.906020.
604 Effect of Switching Systemic Treatment After Stereotactic Radiosurgery for Oligoprogressive, Metastatic Renal Cell Carcinoma.Clin Genitourin Cancer. 2018 Oct;16(5):413-419.e1. doi: 10.1016/j.clgc.2018.07.018. Epub 2018 Aug 17.
605 SCUBE1: a promising biomarker in renal cell cancer.Int Braz J Urol. 2017 Jul-Aug;43(4):638-643. doi: 10.1590/S1677-5538.IBJU.2016.0316.
606 Cyanidin Curtails Renal Cell Carcinoma Tumorigenesis.Cell Physiol Biochem. 2018;46(6):2517-2531. doi: 10.1159/000489658. Epub 2018 May 5.
607 MiR-376a functions as tumor suppressor by targeting SGK3 in renal cell carcinoma.Eur Rev Med Pharmacol Sci. 2019 May;23(9):3726-3732. doi: 10.26355/eurrev_201905_17798.
608 Germline Genetic Biomarkers of Sunitinib Efficacy in Advanced Renal Cell Carcinoma: Results From the RENAL EFFECT Trial.Clin Genitourin Cancer. 2017 Oct;15(5):526-533. doi: 10.1016/j.clgc.2017.02.006. Epub 2017 Feb 27.
609 Autocrine and paracrine STIP1 signaling promote osteolytic bone metastasis in renal cell carcinoma.Oncotarget. 2017 Mar 7;8(10):17012-17026. doi: 10.18632/oncotarget.15222.
610 Chemical shift magnetic resonance imaging for distinguishing minimal-fat renal angiomyolipoma from renal cell carcinoma: a meta-analysis.Eur Radiol. 2018 May;28(5):1854-1861. doi: 10.1007/s00330-017-5141-0. Epub 2017 Nov 24.
611 Down-regulation of C12orf59 is associated with a poor prognosis and VHL mutations in renal cell carcinoma.Oncotarget. 2016 Feb 9;7(6):6824-34. doi: 10.18632/oncotarget.6829.
612 Vitamin D receptor suppresses proliferation and metastasis in renal cell carcinoma cell lines via regulating the expression of the epithelial Ca2+ channel TRPV5.PLoS One. 2018 Apr 16;13(4):e0195844. doi: 10.1371/journal.pone.0195844. eCollection 2018.
613 Expression of resistance factors (P-glycoprotein, glutathione S-transferase-pi, and topoisomerase II) and their interrelationship to proto-oncogene products in renal cell carcinomas.Cancer. 1993 Jun 15;71(12):3981-7. doi: 10.1002/1097-0142(19930615)71:12<3981::aid-cncr2820711231>3.0.co;2-a.
614 DNA methyltransferase inhibitor-mediated apoptosis in the Wnt/-catenin signal pathway in a renal cell carcinoma cell line.Exp Biol Med (Maywood). 2013 Sep;238(9):1009-16. doi: 10.1177/1535370213498984. Epub 2013 Aug 23.
615 The network of DAB2IP-miR-138 in regulating drug resistance of renal cell carcinoma associated with stem-like phenotypes.Oncotarget. 2017 May 9;8(40):66975-66986. doi: 10.18632/oncotarget.17756. eCollection 2017 Sep 15.
616 Expression of two isozymes of acyl-coenzyme A: cholesterol acyltransferase-1 and -2 in clear cell type renal cell carcinoma.Int J Urol. 2008 Feb;15(2):166-70. doi: 10.1111/j.1442-2042.2007.01947.x.
617 Predicted versus observed 30-day perioperative outcomes using the ACS NSQIP surgical risk calculator in patients undergoing partial nephrectomy for renal cell carcinoma.Int Urol Nephrol. 2018 Jul;50(7):1249-1256. doi: 10.1007/s11255-018-1898-6. Epub 2018 Jun 4.
618 Dual-Tracer PET/CT Differentiates 2 Types of Primary Cancers and Metastases in a Patient With Crossed Fused Renal Ectopia.Clin Nucl Med. 2019 Feb;44(2):157-158. doi: 10.1097/RLU.0000000000002390.
619 Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor.J Natl Cancer Inst. 2012 Jun 20;104(12):906-22. doi: 10.1093/jnci/djs232. Epub 2012 May 25.
620 H1/pAIM2 nanoparticles exert anti-tumour effects that is associated with the inflammasome activation in renal carcinoma.J Cell Mol Med. 2018 Nov;22(11):5670-5681. doi: 10.1111/jcmm.13842. Epub 2018 Aug 30.
621 Pyruvate Kinase M2 Activates mTORC1 by Phosphorylating AKT1S1.Sci Rep. 2016 Feb 15;6:21524. doi: 10.1038/srep21524.
622 Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma.Cancer Res. 2005 Jun 1;65(11):4598-606. doi: 10.1158/0008-5472.CAN-04-3371.
623 Expression of the angiopoietins and their receptor Tie2 in human renal clear cell carcinomas; regulation by the von Hippel-Lindau gene and hypoxia.J Pathol. 2002 Dec;198(4):502-10. doi: 10.1002/path.1228.
624 Ankyrin repeat and single KH domain 1 (ANKHD1) drives renal cancer cell proliferation via binding to and altering a subset of miRNAs.J Biol Chem. 2018 Jun 22;293(25):9570-9579. doi: 10.1074/jbc.RA117.000975. Epub 2018 Apr 25.
625 ARPP protein is selectively expressed in renal oncocytoma, but rarely in renal cell carcinomas.Mod Pathol. 2007 Feb;20(2):199-207. doi: 10.1038/modpathol.3800730. Epub 2007 Jan 5.
626 Methylation of the APAF-1 and DAPK-1 promoter region correlates with progression of renal cell carcinoma in North Indian population.Tumour Biol. 2012 Apr;33(2):395-402. doi: 10.1007/s13277-011-0235-9. Epub 2011 Sep 16.
627 High APOBEC3B expression is a predictor of recurrence in patients with low-risk clear cell renal cell carcinoma.Urol Oncol. 2015 Aug;33(8):340.e1-8. doi: 10.1016/j.urolonc.2015.05.009. Epub 2015 Jun 4.
628 Gene expression profiling of chromophobe renal cell carcinomas and renal oncocytomas by Affymetrix GeneChip using pooled and individual tumours.Int J Biol Sci. 2009 Jul 29;5(6):517-27. doi: 10.7150/ijbs.5.517.
629 The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling.Cell Commun Signal. 2017 May 2;15(1):16. doi: 10.1186/s12964-017-0170-5.
630 ARHGAP24 inhibits cell cycle progression, induces apoptosis and suppresses invasion in renal cell carcinoma.Oncotarget. 2016 Aug 9;7(32):51829-51839. doi: 10.18632/oncotarget.10386.
631 Rho GDP dissociation inhibitor- in renal cell carcinoma.Oncol Lett. 2017 Dec;14(6):8190-8196. doi: 10.3892/ol.2017.7233. Epub 2017 Oct 20.
632 Development of a Novel Antibody-Drug Conjugate for the Potential Treatment of Ovarian, Lung, and Renal Cell Carcinoma Expressing TIM-1.Mol Cancer Ther. 2016 Dec;15(12):2946-2954. doi: 10.1158/1535-7163.MCT-16-0393. Epub 2016 Sep 26.
633 Xp11.2 translocation/TFE3 gene fusion renal cell carcinoma with a micropapillary pattern: cases report and literature review.Am J Transl Res. 2019 Jan 15;11(1):327-339. eCollection 2019.
634 ATF2 predicts poor prognosis and promotes malignant phenotypes in renal cell carcinoma.J Exp Clin Cancer Res. 2016 Jul 4;35(1):108. doi: 10.1186/s13046-016-0383-2.
635 Epigenetic silencing of Na,K-ATPase 1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma.Epigenetics. 2014 Apr;9(4):579-86. doi: 10.4161/epi.27795. Epub 2014 Jan 22.
636 Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma.Oncogene. 2011 Mar 24;30(12):1390-401. doi: 10.1038/onc.2010.525. Epub 2010 Dec 6.
637 Receptor tyrosine kinase-like orphan receptor 2 (Ror2) expression creates a poised state of Wnt signaling in renal cancer.J Biol Chem. 2013 Sep 6;288(36):26301-26310. doi: 10.1074/jbc.M113.466086. Epub 2013 Jul 26.
638 Superior antitumor in vitro responses of allogeneic matched sibling compared with autologous patient CD8+ T cells.Cancer Res. 2006 Dec 1;66(23):11447-54. doi: 10.1158/0008-5472.CAN-06-0998.
639 New criteria for improved diagnosis of Bardet-Biedl syndrome: results of a population survey.J Med Genet. 1999 Jun;36(6):437-46.
640 Functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates BHLHE41.Nat Commun. 2016 Jul 7;7:12098. doi: 10.1038/ncomms12098.
641 Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma.Oncogene. 2010 Apr 8;29(14):2104-17. doi: 10.1038/onc.2009.493. Epub 2010 Feb 15.
642 Expression and epigenetic regulatory mechanism of BNIP3 in clear cell renal cell carcinoma.Int J Oncol. 2019 Jan;54(1):348-360. doi: 10.3892/ijo.2018.4603. Epub 2018 Oct 24.
643 BSND is a Novel Immunohistochemical Marker for Oncocytic Salivary Gland Tumors.Pathol Oncol Res. 2018 Apr;24(2):439-444. doi: 10.1007/s12253-017-0248-9. Epub 2017 May 3.
644 BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer. Carcinogenesis. 2009 Apr;30(4):662-70. doi: 10.1093/carcin/bgp042. Epub 2009 Feb 12.
645 Expression and clinical significance of RCDG1 in renal cell carcinoma: a novel renal cancerassociated gene.Mol Med Rep. 2014 Sep;10(3):1583-9. doi: 10.3892/mmr.2014.2388. Epub 2014 Jul 16.
646 Honokiol inhibits c-Met-HO-1 tumor-promoting pathway and its cross-talk with calcineurin inhibitor-mediated renal cancer growth.Sci Rep. 2017 Jul 19;7(1):5900. doi: 10.1038/s41598-017-05455-1.
647 Down-regulation of CacyBP is associated with poor prognosis and the effects on COX-2 expression in breast cancer.Int J Oncol. 2010 Nov;37(5):1261-9. doi: 10.3892/ijo_00000777.
648 Aberrant methylation and loss of CADM2 tumor suppressor expression is associated with human renal cell carcinoma tumor progression.Biochem Biophys Res Commun. 2013 Jun 14;435(4):526-32. doi: 10.1016/j.bbrc.2013.04.074. Epub 2013 May 3.
649 Lead, calcium uptake, and related genetic variants in association with renal cell carcinoma risk in a cohort of male Finnish smokers.Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):191-201. doi: 10.1158/1055-9965.EPI-11-0670. Epub 2011 Nov 15.
650 Anti-neuroblastoma antibody chCE7 binds to an isoform of L1-CAM present in renal carcinoma cells.Int J Cancer. 1999 Oct 29;83(3):401-8. doi: 10.1002/(sici)1097-0215(19991029)83:3<401::aid-ijc17>3.0.co;2-a.
651 New Insights Into the Mechanism of COP9 Signalosome-Cullin-RING Ubiquitin-Ligase Pathway Deregulation in Urological Cancers.Int Rev Cell Mol Biol. 2016;323:181-229. doi: 10.1016/bs.ircmb.2015.12.007. Epub 2016 Feb 16.
652 Evaluating the expression of CARMA3 as a prognostic tumor marker in renal cell carcinoma.Tumour Biol. 2013 Dec;34(6):3431-5. doi: 10.1007/s13277-013-0917-6. Epub 2013 Jun 15.
653 Downregulation of lncRNA SDPR-AS is associated with poor prognosis in renal cell carcinoma.Onco Targets Ther. 2017 Jun 19;10:3039-3047. doi: 10.2147/OTT.S137641. eCollection 2017.
654 Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.J Cell Sci. 2011 Jul 1;124(Pt 13):2132-42. doi: 10.1242/jcs.087122. Epub 2011 Jun 7.
655 Molecular analysis of germline t(3;6) and t(3;12) associated with conventional renal cell carcinomas indicates their rate-limiting role and supports the three-hit model of carcinogenesis.Cancer Genet Cytogenet. 2010 Aug;201(1):15-23. doi: 10.1016/j.cancergencyto.2010.04.018.
656 The suppressing role of miR-622 in renal cell carcinoma progression by down-regulation of CCL18/MAPK signal pathway.Cell Biosci. 2018 Mar 2;8:17. doi: 10.1186/s13578-018-0212-8. eCollection 2018.
657 Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7.Mol Cancer. 2014 Sep 6;13:206. doi: 10.1186/1476-4598-13-206.
658 Change in expression of cyclin G2 in kidney cancer cell and its significance.Tumour Biol. 2014 Apr;35(4):3177-83. doi: 10.1007/s13277-013-1415-6. Epub 2013 Nov 23.
659 CD1d expression in renal cell carcinoma is associated with higher relapse rates, poorer cancer-specific and overall survival.J Clin Pathol. 2015 Mar;68(3):200-5. doi: 10.1136/jclinpath-2014-202735. Epub 2014 Dec 4.
660 t(6;11) renal cell carcinoma: a study of seven cases including two with aggressive behavior, and utility of CD68 (PG-M1) in the differential diagnosis with pure epithelioid PEComa/epithelioid angiomyolipoma.Mod Pathol. 2018 Mar;31(3):474-487. doi: 10.1038/modpathol.2017.144. Epub 2017 Oct 20.
661 Expression of cadherin-8 in renal cell carcinoma and fetal kidney.Int J Cancer. 2002 Oct 1;101(4):327-34. doi: 10.1002/ijc.10623.
662 Cadherin-9 is a novel cell surface marker for the heterogeneous pool of renal fibroblasts.PLoS One. 2007 Aug 1;2(7):e657. doi: 10.1371/journal.pone.0000657.
663 Loss of cadherin related family member 5 (CDHR5) expression in clear cell renal cell carcinoma is a prognostic marker of disease progression.Oncotarget. 2017 Aug 24;8(43):75076-75086. doi: 10.18632/oncotarget.20507. eCollection 2017 Sep 26.
664 Cyclin-dependent kinase-associated protein phosphatase is overexpressed in alcohol-related hepatocellular carcinoma and influences xenograft tumor growth.Oncol Rep. 2013 Mar;29(3):903-10. doi: 10.3892/or.2012.2208. Epub 2012 Dec 24.
665 Upregulation of the KIAA1199 gene is associated with cellular mortality.Cancer Lett. 2006 Jul 28;239(1):71-7. doi: 10.1016/j.canlet.2005.07.028. Epub 2005 Sep 12.
666 Upregulation of centromere protein H is associated with progression of renal cell carcinoma.J Mol Histol. 2015 Oct;46(4-5):377-85. doi: 10.1007/s10735-015-9635-2. Epub 2015 Aug 7.
667 CEP55 promotes epithelial-mesenchymal transition in renal cell carcinoma through PI3K/AKT/mTOR pathway.Clin Transl Oncol. 2019 Jul;21(7):939-949. doi: 10.1007/s12094-018-02012-8. Epub 2019 Jan 3.
668 Induced transcriptional expression of calcium-binding protein S100A1 and S100A10 genes in human renal cell carcinoma.Cancer Lett. 2002 Jan 10;175(1):71-7. doi: 10.1016/s0304-3835(01)00724-8.
669 Clinical significance and prognostic value of chromatin assembly factor-1 overexpression in human solid tumours.Histopathology. 2010 Nov;57(5):716-24. doi: 10.1111/j.1365-2559.2010.03681.x.
670 The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation.Oncotarget. 2016 Apr 19;7(16):21618-30. doi: 10.18632/oncotarget.7822.
671 Chmp1A acts as a tumor suppressor gene that inhibits proliferation of renal cell carcinoma.Cancer Lett. 2012 Jun 28;319(2):190-196. doi: 10.1016/j.canlet.2012.01.010. Epub 2012 Jan 17.
672 DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase.J Biol Chem. 2014 Oct 24;289(43):29975-93. doi: 10.1074/jbc.M114.567073. Epub 2014 Sep 5.
673 Impact of Perioperative Infection on Cancer Specific Survival after Nephrectomy for Renal Cell Carcinoma.J Urol. 2017 Nov;198(5):1027-1032. doi: 10.1016/j.juro.2017.05.070. Epub 2017 May 25.
674 CIP2A Promotes Proliferation, Invasion and Chemoresistance to Cisplatin in Renal Cell Carcinoma.J Cancer. 2018 Oct 17;9(21):4029-4038. doi: 10.7150/jca.25005. eCollection 2018.
675 Genetic clustering of clear cell renal cell carcinoma based on array-comparative genomic hybridization: its association with DNA methylation alteration and patient outcome.Clin Cancer Res. 2008 Sep 1;14(17):5531-9. doi: 10.1158/1078-0432.CCR-08-0443.
676 Prognostic implication of p27Kip1, Skp2 and Cks1 expression in renal cell carcinoma: a tissue microarray study.J Exp Clin Cancer Res. 2008 Oct 15;27(1):51. doi: 10.1186/1756-9966-27-51.
677 Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.Hum Pathol. 2009 Feb;40(2):206-10. doi: 10.1016/j.humpath.2008.07.002. Epub 2008 Sep 16.
678 Immunohistochemical diagnosis of renal neoplasms.Arch Pathol Lab Med. 2011 Jan;135(1):92-109. doi: 10.5858/2010-0478-RAR.1.
679 FOXC2 and CLIP4 : a potential biomarker for synchronous metastasis of ?-cm clear cell renal cell carcinomas.Oncotarget. 2016 Aug 9;7(32):51423-51434. doi: 10.18632/oncotarget.9842.
680 A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23).Oncogene. 2003 Aug 14;22(34):5374-8. doi: 10.1038/sj.onc.1206686.
681 Prognostic and clinicopathological role of high Ki-67 expression in patients with renal cell carcinoma: a systematic review and meta-analysis.Sci Rep. 2017 Mar 13;7:44281. doi: 10.1038/srep44281.
682 The expression of tumstatin is down-regulated in renal carcinoma.Mol Biol Rep. 2010 Jun;37(5):2273-7. doi: 10.1007/s11033-009-9718-9. Epub 2009 Aug 18.
683 COP1 is downregulated in renal cell carcinoma (RCC) and inhibits the migration of RCC ACHN cells invitro.Mol Med Rep. 2016 Aug;14(2):1371-8. doi: 10.3892/mmr.2016.5373. Epub 2016 Jun 7.
684 Cellular retinoic acid binding protein I: expression and functional influence in renal cell carcinoma. Tumour Biol. 2005 Nov-Dec;26(6):313-23. doi: 10.1159/000089262. Epub 2005 Oct 25.
685 Expression and functional influence of cellular retinoic acid-binding protein II in renal cell carcinoma.Urol Int. 2005;75(3):269-76. doi: 10.1159/000087807.
686 Paraganglioma, neuroblastoma, and a SDHB mutation: Resolution of a 30-year-old mystery.Am J Med Genet A. 2010 Jun;152A(6):1531-5. doi: 10.1002/ajmg.a.33384.
687 Knockdown of Collagen Triple Helix Repeat Containing-1 Inhibits the Proliferation and Epithelial-to-Mesenchymal Transition in Renal Cell Carcinoma Cells.Oncol Res. 2016 Oct 27;24(6):477-485. doi: 10.3727/096504016X14685034103716.
688 The expression of Cullin1 is increased in renal cell carcinoma and promotes cancer cell proliferation, migration, and invasion.Tumour Biol. 2016 Sep;37(9):12823-12831. doi: 10.1007/s13277-016-5151-6. Epub 2016 Jul 23.
689 Androgen receptor (AR) signaling promotes RCC progression via increased endothelial cell proliferation and recruitment by modulating AKTNF-BCXCL5 signaling.Sci Rep. 2016 Nov 16;6:37085. doi: 10.1038/srep37085.
690 Downregulation of Human DAB2IP Gene Expression in Renal Cell Carcinoma Results in Resistance to Ionizing Radiation.Clin Cancer Res. 2019 Jul 15;25(14):4542-4551. doi: 10.1158/1078-0432.CCR-18-3004. Epub 2019 Apr 18.
691 The long noncoding RNA KCNQ1DN suppresses the survival of renal cell carcinoma cells through downregulating c-Myc.J Cancer. 2019 Aug 19;10(19):4662-4670. doi: 10.7150/jca.29280. eCollection 2019.
692 Dysregulated D-dopachrome tautomerase, a hypoxia-inducible factor-dependent gene, cooperates with macrophage migration inhibitory factor in renal tumorigenesis.J Biol Chem. 2014 Feb 7;289(6):3713-23. doi: 10.1074/jbc.M113.500694. Epub 2013 Dec 19.
693 DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.Cancer Res. 2012 Nov 15;72(22):5867-77. doi: 10.1158/0008-5472.CAN-12-1645. Epub 2012 Sep 27.
694 Identification of novel targets for antiangiogenic therapy by comparing the gene expressions of tumor and normal endothelial cells.Cancer Sci. 2014 May;105(5):560-7. doi: 10.1111/cas.12394. Epub 2014 Apr 19.
695 Human alpha-defensins HNPs-1, -2, and -3 in renal cell carcinoma: influences on tumor cell proliferation.Am J Pathol. 2002 Apr;160(4):1311-24. doi: 10.1016/s0002-9440(10)62558-8.
696 Involvement of erbB4 and tumor marker genes in renal carcinoma regulatory network.Saudi J Biol Sci. 2017 Dec;24(8):1787-1791. doi: 10.1016/j.sjbs.2017.11.013. Epub 2017 Nov 10.
697 Increased DKC1 expression in glioma and its significance in tumor cell proliferation, migration and invasion.Invest New Drugs. 2019 Dec;37(6):1177-1186. doi: 10.1007/s10637-019-00748-w. Epub 2019 Mar 7.
698 Aberrant promoter methylation of DLEC1, a critical 3p22 tumor suppressor for renal cell carcinoma, is associated with more advanced tumor stage.J Urol. 2010 Aug;184(2):731-7. doi: 10.1016/j.juro.2010.03.108. Epub 2010 Jun 19.
699 Metastatic renal clear cell carcinoma in the parotid gland: a study of immunohistochemical profile and cell adhesion molecules (CAMs) expression in two cases.Pathol Oncol Res. 2007;13(2):161-5. doi: 10.1007/BF02893494. Epub 2007 Jul 3.
700 TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation Cancers.Am J Surg Pathol. 2016 Jun;40(6):723-37. doi: 10.1097/PAS.0000000000000631.
701 Overexpression of DLC-1 induces cell apoptosis and proliferation inhibition in the renal cell carcinoma.Cancer Lett. 2009 Sep 28;283(1):59-67. doi: 10.1016/j.canlet.2009.03.025. Epub 2009 Apr 19.
702 Upregulated expression of eIF3C is associated with malignant behavior in renal cell carcinoma.Int J Oncol. 2019 Dec;55(6):1385-1395. doi: 10.3892/ijo.2019.4903. Epub 2019 Oct 21.
703 EIF3D promotes sunitinib resistance of renal cell carcinoma by interacting with GRP78 and inhibiting its degradation.EBioMedicine. 2019 Nov;49:189-201. doi: 10.1016/j.ebiom.2019.10.030. Epub 2019 Oct 26.
704 Hypoxic 3D in vitro culture models reveal distinct resistance processes to TKIs in renal cancer cells.Cell Biosci. 2017 Dec 16;7:71. doi: 10.1186/s13578-017-0197-8. eCollection 2017.
705 The Ets transcription factor ELF5 functions as a tumor suppressor in the kidney.Twin Res Hum Genet. 2011 Aug;14(4):316-22. doi: 10.1375/twin.14.4.316.
706 Refined mapping of the human Ets-related gene Elk-1 to Xp11.2-p11.4, distal to the OATL1 region.Hum Genet. 1994 Oct;94(4):442-4. doi: 10.1007/BF00201610.
707 Genomic profiling identifies alterations in TGFbeta signaling through loss of TGFbeta receptor expression in human renal cell carcinogenesis and progression.Oncogene. 2003 Sep 11;22(39):8053-62. doi: 10.1038/sj.onc.1206835.
708 Senescence-associated protein p400 is a prognostic marker in renal cell carcinoma.Oncol Rep. 2013 Nov;30(5):2245-53. doi: 10.3892/or.2013.2698. Epub 2013 Aug 26.
709 Higher expression of XPF is a critical factor in intrinsic chemotherapy resistance of human renal cell carcinoma.Int J Cancer. 2016 Dec 15;139(12):2827-2837. doi: 10.1002/ijc.30396. Epub 2016 Sep 16.
710 ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathway.Cancer Gene Ther. 2019 Sep;26(9-10):323-333. doi: 10.1038/s41417-018-0064-8. Epub 2018 Nov 21.
711 Functional analysis of fatty acid binding protein 7 and its effect on fatty acid of renal cell carcinoma cell lines.BMC Cancer. 2017 Mar 14;17(1):192. doi: 10.1186/s12885-017-3184-x.
712 Ectopic expression of the TERE1 (UBIAD1) protein inhibits growth of renal clear cell carcinoma cells: altered metabolic phenotype associated with reactive oxygen species, nitric oxide and SXR target genes involved in cholesterol and lipid metabolism.Int J Oncol. 2013 Aug;43(2):638-52. doi: 10.3892/ijo.2013.1985. Epub 2013 Jun 12.
713 Fibulin-1 is down-regulated through promoter hypermethylation and suppresses renal cell carcinoma progression.J Urol. 2013 Jul;190(1):291-301. doi: 10.1016/j.juro.2013.01.098. Epub 2013 Feb 4.
714 FBXO22 Suppresses Metastasis in Human Renal Cell Carcinoma via Inhibiting MMP-9-Mediated Migration and Invasion and VEGF-Mediated Angiogenesis.Int J Biol Sci. 2019 Jan 24;15(3):647-656. doi: 10.7150/ijbs.31293. eCollection 2019.
715 Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma.Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):718-25. doi: 10.1158/1078-0432.CCR-05-0857.
716 Kindlin? promotes clear cell renal cell carcinoma progression through the Wnt signaling pathway.Oncol Rep. 2017 Sep;38(3):1551-1560. doi: 10.3892/or.2017.5789. Epub 2017 Jul 4.
717 Identification of fibroblast growth factor-5 as an overexpressed antigen in multiple human adenocarcinomas.Cancer Res. 2001 Jul 15;61(14):5511-6.
718 Smad4 suppresses the progression of renal cell carcinoma via the activation of forkhead box protein H1.Mol Med Rep. 2015 Apr;11(4):2717-22. doi: 10.3892/mmr.2014.3061. Epub 2014 Dec 8.
719 Cell-Type-Specific Gene Programs of the Normal Human Nephron Define Kidney Cancer Subtypes.Cell Rep. 2017 Aug 8;20(6):1476-1489. doi: 10.1016/j.celrep.2017.07.043.
720 CircRNA ZNF609 functions as a competitive endogenous RNA to regulate FOXP4 expression by sponging miR-138-5p in renal carcinoma.J Cell Physiol. 2019 Jul;234(7):10646-10654. doi: 10.1002/jcp.27744. Epub 2018 Nov 27.
721 Role of secreted frizzled-related protein 3 in human renal cell carcinoma.Cancer Res. 2010 Mar 1;70(5):1896-905. doi: 10.1158/0008-5472.CAN-09-3549. Epub 2010 Feb 16.
722 miR-124 represses FZD5 to attenuate P-glycoprotein-mediated chemo-resistance in renal cell carcinoma.Tumour Biol. 2015 Sep;36(9):7017-26. doi: 10.1007/s13277-015-3369-3. Epub 2015 Apr 12.
723 Frizzled 8 promotes the cell proliferation and metastasis of renal cell carcinoma.Oncotarget. 2017 Sep 8;8(45):78989-79002. doi: 10.18632/oncotarget.20742. eCollection 2017 Oct 3.
724 Cancer-associated expression of glycolipid sulfotransferase gene in human renal cell carcinoma cells.Cancer Res. 1998 Sep 1;58(17):3800-5.
725 Roles of GalNAc-disialyl Lactotetraosyl Antigens in Renal Cancer Cells.Sci Rep. 2018 May 4;8(1):7017. doi: 10.1038/s41598-018-25521-6.
726 Polypeptide N-acetylgalactosaminyl transferase 3 independently predicts high-grade tumours and poor prognosis in patients with renal cell carcinomas.Br J Cancer. 2013 Jul 23;109(2):472-81. doi: 10.1038/bjc.2013.331. Epub 2013 Jun 25.
727 GATA5 CpG island hypermethylation is an independent predictor for poor clinical outcome in renal cell carcinoma.Oncol Rep. 2014 Apr;31(4):1523-30. doi: 10.3892/or.2014.3030. Epub 2014 Feb 18.
728 Vitamin D binding protein and risk of renal cell carcinoma in the prostate, lung, colorectal and ovarian cancer screening trial.Int J Cancer. 2020 Aug 1;147(3):669-674. doi: 10.1002/ijc.32758. Epub 2019 Nov 19.
729 Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.Clin Cancer Res. 2008 Dec 1;14(23):7956-62. doi: 10.1158/1078-0432.CCR-08-1199.
730 Identifying CD82 (KAI1) as a marker for human chromophobe renal cell carcinoma.Histopathology. 2009 Dec;55(6):687-95. doi: 10.1111/j.1365-2559.2009.03449.x.
731 MiR-30b-5p functions as a tumor suppressor in cell proliferation, metastasis and epithelial-to-mesenchymal transition by targeting G-protein subunit -13 in renal cell carcinoma.Gene. 2017 Aug 30;626:275-281. doi: 10.1016/j.gene.2017.05.040. Epub 2017 May 20.
732 Identification of novel VHL target genes and relationship to hypoxic response pathways.Oncogene. 2005 Jun 30;24(28):4549-58. doi: 10.1038/sj.onc.1208649.
733 Golgi Phosphoprotein 3 Promotes Malignant Phenotypes via FAK/Raf/MEK and Wnt/-Catenin Signaling Pathways in Human Renal Cell Carcinoma.J Biomed Nanotechnol. 2019 Aug 1;15(8):1812-1823. doi: 10.1166/jbn.2019.2804.
734 Detection of transcript for brain-type fatty Acid-binding protein in tumor and urine of patients with renal cell carcinoma.Urology. 2007 Feb;69(2):236-40. doi: 10.1016/j.urology.2006.09.060.
735 Association of glutathione S-transferase M1, T1, and P1 polymorphisms with renal cell carcinoma: evidence from 11 studies.Tumour Biol. 2014 Apr;35(4):3867-73. doi: 10.1007/s13277-013-1513-5. Epub 2013 Dec 15.
736 Global histone acetylation levels: prognostic relevance in patients with renal cell carcinoma.Cancer Sci. 2010 Dec;101(12):2664-9. doi: 10.1111/j.1349-7006.2010.01717.x. Epub 2010 Sep 1.
737 Differential expression of TIM-3 between primary and metastatic sites in renal cell carcinoma.BMC Cancer. 2019 Jan 10;19(1):49. doi: 10.1186/s12885-019-5273-5.
738 Prognostic and diagnostic relevance of hypermethylated in cancer 1 (HIC1) CpG island methylation in renal cell carcinoma.Int J Oncol. 2012 May;40(5):1650-8. doi: 10.3892/ijo.2012.1367. Epub 2012 Feb 10.
739 Dominant-negative HIF-3 alpha 4 suppresses VHL-null renal cell carcinoma progression.Cell Cycle. 2007 Nov 15;6(22):2810-6. doi: 10.4161/cc.6.22.4947. Epub 2007 Aug 29.
740 Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene.Oncogene. 2004 Aug 5;23(35):5941-9. doi: 10.1038/sj.onc.1207789.
741 HLA-G and HLA-E specific mRNAs connote opposite prognostic significance in renal cell carcinoma.Diagn Pathol. 2012 May 29;7:58. doi: 10.1186/1746-1596-7-58.
742 Molecular characterization of kidney cancer: association of hyaluronic acid family with histological subtypes and metastasis.Cancer. 2012 May 1;118(9):2394-402. doi: 10.1002/cncr.26520. Epub 2011 Sep 1.
743 Cytoplasmic Accumulation of Heterogeneous Nuclear Ribonucleoprotein K Strongly Promotes Tumor Invasion in Renal Cell Carcinoma Cells.PLoS One. 2015 Dec 29;10(12):e0145769. doi: 10.1371/journal.pone.0145769. eCollection 2015.
744 Heterogeneous nuclear ribonucleoprotein U-like 1 and Poly (ADP-ribose) polymerase 1 are downregulated in renal cell carcinoma and connected with the prognosis.Cancer Biomark. 2013 Jan 1;13(6):411-5. doi: 10.3233/CBM-140390.
745 HOX gene expression in normal and neoplastic human kidney.Int J Cancer. 1992 Jul 30;51(6):892-7. doi: 10.1002/ijc.2910510610.
746 Overexpression of HOXC11 homeobox gene in clear cell renal cell carcinoma induces cellular proliferation and is associated with poor prognosis.Tumour Biol. 2015 Apr;36(4):2821-9. doi: 10.1007/s13277-014-2909-6. Epub 2014 Dec 5.
747 Targeting the testis-specific heat-shock protein 70-2 (HSP70-2) reduces cellular growth, migration, and invasion in renal cell carcinoma cells.Tumour Biol. 2014 Dec;35(12):12695-706. doi: 10.1007/s13277-014-2594-5. Epub 2014 Sep 12.
748 Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.Int J Oncol. 2014 May;44(5):1490-8. doi: 10.3892/ijo.2014.2314. Epub 2014 Feb 27.
749 Evaluation of renal cell carcinoma vaccines targeting carbonic anhydrase IX using heat shock protein 110.Cancer Immunol Immunother. 2007 Jul;56(7):1097-105. doi: 10.1007/s00262-006-0258-z. Epub 2006 Dec 5.
750 HtrA3 is regulated by 15-deoxy-Delta12,14-prostaglandin J2 independently of PPARgamma in clear cell renal cell carcinomas.Biochem Biophys Res Commun. 2010 Apr 9;394(3):453-8. doi: 10.1016/j.bbrc.2009.11.163. Epub 2009 Nov 29.
751 Nivolumab in the treatment of advanced renal cell carcinoma.Future Oncol. 2018 Jul;14(17):1679-1689. doi: 10.2217/fon-2017-0533. Epub 2018 Feb 20.
752 Sensitization of renal carcinoma to radiation using alpha interferon (IFNA) gene transfection.Radiat Res. 1997 Nov;148(5):443-8.
753 miR-372 suppresses tumour proliferation and invasion by targeting IGF2BP1 in renal cell carcinoma.Cell Prolif. 2015 Oct;48(5):593-9. doi: 10.1111/cpr.12207.
754 External validation of IMP3 expression as an independent prognostic marker for metastatic progression and death for patients with clear cell renal cell carcinoma.Cancer. 2008 Apr 1;112(7):1471-9. doi: 10.1002/cncr.23296.
755 Insulin like growth factor binding protein 4 promotes GBM progression and regulates key factors involved in EMT and invasion.J Neurooncol. 2014 Feb;116(3):455-64. doi: 10.1007/s11060-013-1324-y. Epub 2014 Jan 7.
756 Significant association of interleukin 10 receptor mRNA levels with renal cell carcinoma metastasis.Biomed Res. 2008 Feb;29(1):19-25. doi: 10.2220/biomedres.29.19.
757 Sensitization of human renal cell carcinoma cells to cis-diamminedichloroplatinum(II) by anti-interleukin 6 monoclonal antibody or anti-interleukin 6 receptor monoclonal antibody. Cancer Res. 1995 Feb 1;55(3):590-6.
758 Immunoreactivity of CD10 and inhibin alpha in differentiating hemangioblastoma of central nervous system from metastatic clear cell renal cell carcinoma.Mod Pathol. 2005 Jun;18(6):788-94. doi: 10.1038/modpathol.3800351.
759 SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML.PLoS One. 2018 Feb 7;13(2):e0191510. doi: 10.1371/journal.pone.0191510. eCollection 2018.
760 Hyper-interleukin-11 novel designer molecular adjuvant targeting gp130 for whole cell cancer vaccines.Expert Opin Biol Ther. 2011 Dec;11(12):1555-67. doi: 10.1517/14712598.2011.627852. Epub 2011 Oct 14.
761 Diverse CD8+ T-cell responses to renal cell carcinoma antigens in patients treated with an autologous granulocyte-macrophage colony-stimulating factor gene-transduced renal tumor cell vaccine.Cancer Res. 2005 Feb 1;65(3):1079-88.
762 Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer.Elife. 2018 Oct 25;7:e37925. doi: 10.7554/eLife.37925.
763 Genetic variation in platelet integrin alphabeta (GPIIb/IIIa) and the metastatic potential of renal cell carcinoma.BJU Int. 2006 Jul;98(1):201-4. doi: 10.1111/j.1464-410X.2006.06196.x.
764 Acquired resistance to temsirolimus is associated with integrin 7 driven chemotactic activity of renal cell carcinoma in vitro.Oncotarget. 2018 Apr 10;9(27):18747-18759. doi: 10.18632/oncotarget.24650. eCollection 2018 Apr 10.
765 Antitumor effect and biological pathways of a recombinant adeno-associated virus as a human renal cell carcinoma suppressor.Tumour Biol. 2014 Nov;35(11):10993-1003. doi: 10.1007/s13277-014-2393-z. Epub 2014 Aug 5.
766 Jam3 promotes migration and suppresses apoptosis of renal carcinoma cell lines.Int J Mol Med. 2018 Nov;42(5):2923-2929. doi: 10.3892/ijmm.2018.3854. Epub 2018 Sep 4.
767 Kank1 reexpression induced by 5-Aza-2'-deoxycytidine suppresses nasopharyngeal carcinoma cell proliferation and promotes apoptosis.Int J Clin Exp Pathol. 2015 Feb 1;8(2):1658-65. eCollection 2015.
768 Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma.Biochem Biophys Res Commun. 2007 May 18;356(4):864-71. doi: 10.1016/j.bbrc.2007.03.080. Epub 2007 Mar 26.
769 Correlation of low expression of hMOF with clinicopathological features of colorectal carcinoma, gastric cancer and renal cell carcinoma.Int J Oncol. 2014 Apr;44(4):1207-14. doi: 10.3892/ijo.2014.2266. Epub 2014 Jan 21.
770 Mapping of constitutional translocation breakpoints in renal cell cancer patients: identification of KCNIP4 as a candidate gene.Cancer Genet Cytogenet. 2007 Nov;179(1):11-8. doi: 10.1016/j.cancergencyto.2007.07.005.
771 A polymorphism in the splice donor site of ZNF419 results in the novel renal cell carcinoma-associated minor histocompatibility antigen ZAPHIR.PLoS One. 2011;6(6):e21699. doi: 10.1371/journal.pone.0021699. Epub 2011 Jun 28.
772 Expression and functional role of miR-29b in renal cell carcinoma.Int J Clin Exp Pathol. 2015 Nov 1;8(11):14161-70. eCollection 2015.
773 A novel HDAC inhibitor OBP-801 and a PI3K inhibitor LY294002 synergistically induce apoptosis via the suppression of survivin and XIAP in renal cell carcinoma.Int J Oncol. 2013 Oct;43(4):1080-6. doi: 10.3892/ijo.2013.2042. Epub 2013 Jul 30.
774 Krppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferation.PLoS One. 2012;7(1):e30429. doi: 10.1371/journal.pone.0030429. Epub 2012 Jan 19.
775 Prognostic implications of the immunohistochemical expression of human kallikreins 5, 6, 10 and 11 in renal cell carcinoma.Tumour Biol. 2006;27(1):1-7. doi: 10.1159/000090150. Epub 2005 Dec 8.
776 Re-evaluation of 33 'unclassified' eosinophilic renal cell carcinomas in young patients.Histopathology. 2018 Mar;72(4):588-600. doi: 10.1111/his.13395. Epub 2017 Dec 4.
777 KRT6 interacting with notch1 contributes to progression of renal cell carcinoma, and aliskiren inhibits renal carcinoma cell lines proliferation in vitro.Int J Clin Exp Pathol. 2015 Aug 1;8(8):9182-8. eCollection 2015.
778 Methylationassociated inactivation of LATS1 and its effect on demethylation or overexpression on YAP and cell biological function in human renal cell carcinoma.Int J Oncol. 2014 Dec;45(6):2511-21. doi: 10.3892/ijo.2014.2687. Epub 2014 Sep 30.
779 Four new human renal cell carcinoma cell lines expressing globo-series gangliosides.Tohoku J Exp Med. 1999 Oct;189(2):95-105. doi: 10.1620/tjem.189.95.
780 Profilin 1 overexpression in renal cell carcinoma.Int J Urol. 2011 Jan;18(1):63-71. doi: 10.1111/j.1442-2042.2010.02670.x. Epub 2010 Nov 22.
781 LRIG1 and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT--PCR and immunohistochemical analysis.Br J Cancer. 2003 Oct 6;89(7):1285-9. doi: 10.1038/sj.bjc.6601208.
782 Over expression of HIF1 is associated with inactivation of both LimD1 and VHL in renal cell carcinoma: Clinical importance.Pathol Res Pract. 2017 Dec;213(12):1477-1481. doi: 10.1016/j.prp.2017.10.009. Epub 2017 Oct 10.
783 Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction.Cancer. 2000 Jul 1;89(1):152-64.
784 Methylation pattern of the putative tumor-suppressor gene LRRC3B promoter in clear cell renal cell carcinomas.Mol Med Rep. 2012 Feb;5(2):509-12. doi: 10.3892/mmr.2011.681. Epub 2011 Nov 16.
785 The t(1;3) breakpoint-spanning genes LSAMP and NORE1 are involved in clear cell renal cell carcinomas.Cancer Cell. 2003 Nov;4(5):405-13. doi: 10.1016/s1535-6108(03)00269-1.
786 Identification of TGF--activated kinase 1 as a possible novel target for renal cell carcinoma intervention.Biochem Biophys Res Commun. 2014 Oct 10;453(1):106-11. doi: 10.1016/j.bbrc.2014.09.070. Epub 2014 Sep 26.
787 Generation of RAGE-1 and MAGE-9 peptide-specific cytotoxic T-lymphocyte lines for transfer in patients with renal cell carcinoma.Int J Cancer. 2005 Nov 1;117(2):256-64. doi: 10.1002/ijc.21200.
788 MAGED4-expression in renal cell carcinoma and identification of an HLA-A*25-restricted MHC class I ligand from solid tumor tissue.Cancer Biol Ther. 2005 Sep;4(9):943-8. doi: 10.4161/cbt.4.9.1907. Epub 2005 Sep 8.
789 Role of the RNA-binding protein HuR in human renal cell carcinoma.Carcinogenesis. 2010 Jun;31(6):1018-26. doi: 10.1093/carcin/bgq052. Epub 2010 Mar 10.
790 MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancer.PLoS One. 2012;7(9):e46001. doi: 10.1371/journal.pone.0046001. Epub 2012 Sep 27.
791 Defects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis.Aging (Albany NY). 2016 May;8(5):977-85. doi: 10.18632/aging.100957.
792 Linkage of microRNA and proteome-based profiling data sets: a perspective for the priorization of candidate biomarkers in renal cell carcinoma?.J Proteome Res. 2011 Jan 7;10(1):191-9. doi: 10.1021/pr1011137.
793 Development of novel reversal agents, imidazothiazole derivatives, targeting MDR1- and MRP-mediated multidrug resistance.Oncol Res. 1998;10(3):123-32.
794 Clinical and Molecular Features of Renal and Pheochromocytoma/Paraganglioma Tumor Association Syndrome (RAPTAS): Case Series and Literature Review.J Clin Endocrinol Metab. 2017 Nov 1;102(11):4013-4022. doi: 10.1210/jc.2017-00562.
795 Myoglobin expression in renal cell carcinoma is regulated by hypoxia.Exp Mol Pathol. 2013 Dec;95(3):307-12. doi: 10.1016/j.yexmp.2013.09.003. Epub 2013 Sep 25.
796 Genetic susceptibility to renal cell carcinoma: the role of DNA double-strand break repair pathway.Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2366-73. doi: 10.1158/1055-9965.EPI-08-0259.
797 Primary microcephaly gene MCPH1 shows a novel molecular biomarker of human renal carcinoma and is regulated by miR-27a.Int J Clin Exp Pathol. 2014 Jul 15;7(8):4895-903. eCollection 2014.
798 Knockdown of MSP58 inhibits the proliferation and metastasis in human renal cell carcinoma cells.Biomed Pharmacother. 2017 Jul;91:54-59. doi: 10.1016/j.biopha.2017.04.036. Epub 2017 May 23.
799 Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types.Oncotarget. 2016 Apr 26;7(17):23043-23055. doi: 10.18632/oncotarget.8469.
800 A Rare Partner of TFE3 in the Xp11 Translocation Renal Cell Carcinoma: Clinicopathological Analyses and Detection of MED15-TFE3 Fusion.Biomed Res Int. 2019 Nov 11;2019:5974089. doi: 10.1155/2019/5974089. eCollection 2019.
801 The M6A methyltransferase METTL3: acting as a tumor suppressor in renal cell carcinoma.Oncotarget. 2017 Oct 10;8(56):96103-96116. doi: 10.18632/oncotarget.21726. eCollection 2017 Nov 10.
802 Expression of the matrix Gla protein in urogenital malignancies.Int J Cancer. 1992 Oct 21;52(4):534-7. doi: 10.1002/ijc.2910520406.
803 Loss of PIG3 increases HIF-1 level by promoting protein synthesis via mTOR pathway in renal cell carcinoma cells.Oncotarget. 2016 May 10;7(19):27176-84. doi: 10.18632/oncotarget.8401.
804 Induction of cell cycle arrest by increasing GTPRhoA levels via Taxolinduced microtubule polymerization in renal cell carcinoma.Mol Med Rep. 2017 Jun;15(6):4273-4279. doi: 10.3892/mmr.2017.6543. Epub 2017 May 3.
805 MTHFD2 links RNA methylation to metabolic reprogramming in renal cell carcinoma.Oncogene. 2019 Aug;38(34):6211-6225. doi: 10.1038/s41388-019-0869-4. Epub 2019 Jul 9.
806 Mitochondrial E3 ubiquitin ligase 1 promotes autophagy flux to suppress the development of clear cell renal cell carcinomas.Cancer Sci. 2019 Nov;110(11):3533-3542. doi: 10.1111/cas.14192. Epub 2019 Sep 28.
807 MXRA5 is a TGF-1-regulated human protein with anti-inflammatory and anti-fibrotic properties.J Cell Mol Med. 2017 Jan;21(1):154-164. doi: 10.1111/jcmm.12953. Epub 2016 Sep 6.
808 NMMHC-IIA-dependent nuclear location of CXCR4 promotes migration and invasion in renal cell carcinoma.Oncol Rep. 2016 Nov;36(5):2681-2688. doi: 10.3892/or.2016.5082. Epub 2016 Sep 12.
809 Aberrant expression of napsin A in a subset of malignant lymphomas.Histol Histopathol. 2016 Feb;31(2):213-21. doi: 10.14670/HH-11-669. Epub 2015 Sep 24.
810 DNA repair system and renal cell carcinoma prognosis: under the influence of NBS1.Med Oncol. 2015 Nov;32(11):255. doi: 10.1007/s12032-015-0701-0. Epub 2015 Oct 22.
811 The genetic locus NRC-1 within chromosome 3p12 mediates tumor suppression in renal cell carcinoma independently of histological type, tumor microenvironment, and VHL mutation.Cancer Res. 1999 May 1;59(9):2182-9.
812 Detection of mitochondrial genome depletion by a novel cDNA in renal cell carcinoma.Lab Invest. 1996 Mar;74(3):592-9.
813 Neurofilament Heavy polypeptide CpG island methylation associates with prognosis of renal cell carcinoma and prediction of antivascular endothelial growth factor therapy response.Cancer Med. 2014 Apr;3(2):300-9. doi: 10.1002/cam4.181. Epub 2014 Jan 27.
814 Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.Cancer Sci. 2015 May;106(5):656-64. doi: 10.1111/cas.12649. Epub 2015 Mar 26.
815 Inverse relationship of epidermal growth factor receptor and HER2/neu gene expression in human renal cell carcinoma.Cancer Res. 1990 Aug 1;50(15):4504-9.
816 The plasma membrane sialidase NEU3 regulates the malignancy of renal carcinoma cells by controlling 1 integrin internalization and recycling.J Biol Chem. 2012 Dec 14;287(51):42835-45. doi: 10.1074/jbc.M112.407718. Epub 2012 Nov 8.
817 Analysis of the regulation of fatty acid binding protein 7 expression in human renal carcinoma cell lines.BMC Mol Biol. 2011 Jul 19;12:31. doi: 10.1186/1471-2199-12-31.
818 MDM2 interacts with NME2 (non-metastatic cells 2, protein) and suppresses the ability of NME2 to negatively regulate cell motility.Carcinogenesis. 2011 Aug;32(8):1133-42. doi: 10.1093/carcin/bgr070. Epub 2011 Apr 18.
819 Expression of apoptotic tumour necrosis factor receptor-associated factor, caspase recruitment domain and cell death-inducing DFF-45 effector genes in therapy-treated renal cell carcinoma.Nephrology (Carlton). 2009 Apr;14(2):205-12. doi: 10.1111/j.1440-1797.2008.01027.x.
820 Xp11.2 translocation renal neoplasm with features of TFE3 rearrangement associated renal cell carcinoma and Xp11 translocation renal mesenchymal tumor with melanocytic differentiation harboring NONO-TFE3 fusion gene.Pathol Res Pract. 2019 Sep;215(9):152521. doi: 10.1016/j.prp.2019.152521. Epub 2019 Jun 27.
821 Characterization of Niemann-Pick Type C2 protein expression in multiple cancers using a novel NPC2 monoclonal antibody.PLoS One. 2013 Oct 17;8(10):e77586. doi: 10.1371/journal.pone.0077586. eCollection 2013.
822 Double stranded-RNA-mediated activation of P21 gene induced apoptosis and cell cycle arrest in renal cell carcinoma.Int J Cancer. 2009 Jul 15;125(2):446-52. doi: 10.1002/ijc.24370.
823 NUB1, an interferon-inducible protein, mediates anti-proliferative actions and apoptosis in renal cell carcinoma cells through cell-cycle regulation.Br J Cancer. 2010 Mar 2;102(5):873-82. doi: 10.1038/sj.bjc.6605574. Epub 2010 Feb 16.
824 Downregulation of nucleolar and spindle-associated protein1 expression suppresses cell migration, proliferation and invasion in renal cell carcinoma.Oncol Rep. 2016 Sep;36(3):1506-16. doi: 10.3892/or.2016.4955. Epub 2016 Jul 20.
825 Odd-skipped related transcription factor 1 (OSR1) suppresses tongue squamous cell carcinoma migration and invasion through inhibiting NF-B pathway.Eur J Pharmacol. 2018 Nov 15;839:33-39. doi: 10.1016/j.ejphar.2018.09.020. Epub 2018 Sep 19.
826 P3H4 affects renal carcinoma through up-regulating miR-1/133a.Eur Rev Med Pharmacol Sci. 2018 Aug;22(16):5180-5186. doi: 10.26355/eurrev_201808_15714.
827 High-resolution analysis of DNA copy number alterations and gene expression in renal clear cell carcinoma.J Pathol. 2007 Dec;213(4):392-401. doi: 10.1002/path.2239.
828 Immunohistochemical profiles in primary lung cancers and epithelial pulmonary metastases.Hum Pathol. 2019 Feb;84:221-230. doi: 10.1016/j.humpath.2018.10.009. Epub 2018 Oct 31.
829 Aberrant Promoter Methylation of PCDH17 (Protocadherin 17) in Serum and its Clinical Significance in Renal Cell Carcinoma.Med Sci Monit. 2017 Jul 8;23:3318-3323. doi: 10.12659/msm.902077.
830 Association between protocadherin 8 promoter hypermethylation and the pathological status of prostate cancer.Oncol Lett. 2017 Aug;14(2):1657-1664. doi: 10.3892/ol.2017.6282. Epub 2017 May 31.
831 KIAA0101 is associated with human renal cell carcinoma proliferation and migration induced by erythropoietin.Oncotarget. 2016 Mar 22;7(12):13520-37. doi: 10.18632/oncotarget.5876.
832 Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility.Endocr Relat Cancer. 2010 Dec 21;18(1):73-83. doi: 10.1677/ERC-10-0113. Print 2011 Feb.
833 Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer.Hum Mol Genet. 2013 Feb 15;22(4):825-31. doi: 10.1093/hmg/dds489. Epub 2012 Nov 25.
834 Caspase-8 and its inhibitors in RCCs in vivo: the prominent role of ARC.Apoptosis. 2008 Jul;13(7):938-49. doi: 10.1007/s10495-008-0225-6.
835 Profilin-1 expression is associated with high grade and stage and decreased disease-free survival in renal cell carcinoma.Hum Pathol. 2015 May;46(5):673-80. doi: 10.1016/j.humpath.2014.11.007. Epub 2014 Nov 26.
836 MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma.Carcinogenesis. 2012 Feb;33(2):294-300. doi: 10.1093/carcin/bgr286. Epub 2011 Dec 9.
837 Inhibition of MMP-9 using a pyrrole-imidazole polyamide reduces cell invasion in renal cell carcinoma.Int J Oncol. 2013 Nov;43(5):1441-6. doi: 10.3892/ijo.2013.2073. Epub 2013 Aug 21.
838 Integrin 5 triggers the metastatic potential in renal cell carcinoma.Oncotarget. 2017 Nov 18;8(64):107530-107542. doi: 10.18632/oncotarget.22501. eCollection 2017 Dec 8.
839 Nuclear factor-B signaling pathway is involved in phospholipase C-regulated proliferation in human renal cell carcinoma cells.Mol Cell Biochem. 2014 Apr;389(1-2):265-75. doi: 10.1007/s11010-013-1948-4. Epub 2014 Feb 8.
840 Bioplasmonic paper-based assay for perilipin-2 non-invasively detects renal cancer.Kidney Int. 2019 Dec;96(6):1417-1421. doi: 10.1016/j.kint.2019.08.020. Epub 2019 Sep 3.
841 Targeting neddylation pathway with MLN4924 (Pevonedistat) induces NOXA-dependent apoptosis in renal cell carcinoma.Biochem Biophys Res Commun. 2017 Sep 2;490(4):1183-1188. doi: 10.1016/j.bbrc.2017.06.179. Epub 2017 Jun 29.
842 Expression level of CXCL7 in peripheral blood cells is a potential biomarker for the diagnosis of renal cell carcinoma.Cancer Sci. 2017 Dec;108(12):2495-2502. doi: 10.1111/cas.13414. Epub 2017 Oct 25.
843 Liprin-4 is a new hypoxia-inducible target gene required for maintenance of cell-cell contacts.Exp Cell Res. 2010 Oct 15;316(17):2883-92. doi: 10.1016/j.yexcr.2010.06.022. Epub 2010 Jul 1.
844 Aberrant Methylation of the 1p36 Tumor Suppressor Gene RIZ1 in Renal Cell Carcinoma.Asian Pac J Cancer Prev. 2015;16(9):4071-5. doi: 10.7314/apjcp.2015.16.9.4071.
845 PRKX, TTBK2 and RSK4 expression causes Sunitinib resistance in kidney carcinoma- and melanoma-cell lines.Int J Cancer. 2012 Jul 15;131(2):E45-55. doi: 10.1002/ijc.26486. Epub 2012 Feb 28.
846 Tumor signatures of PTHLH overexpression, high serum calcium, and poor prognosis were observed exclusively in clear cell but not non clear cell renal carcinomas.Cancer Med. 2014 Aug;3(4):845-54. doi: 10.1002/cam4.270. Epub 2014 May 26.
847 A homozygous deletion within the carbonic anhydrase-like domain of the Ptprg gene in murine L-cells.Cancer Res. 1993 Apr 1;53(7):1498-502.
848 Diagnostic value of cytokeratin 7 and parvalbumin in differentiating chromophobe renal cell carcinoma from renal oncocytoma.Anal Quant Cytol Histol. 2006 Aug;28(4):228-36.
849 Paxillin: application of immunohistochemistry to the diagnosis of chromophobe renal cell carcinoma and oncocytoma.Appl Immunohistochem Mol Morphol. 2001 Dec;9(4):315-8. doi: 10.1097/00129039-200112000-00005.
850 YueF overexpression inhibits cell proliferation partly through p21 upregulation in renal cell carcinoma.Int J Mol Sci. 2011;12(4):2477-87. doi: 10.3390/ijms12042477. Epub 2011 Apr 11.
851 Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.Oncol Rep. 2009 Feb;21(2):305-12.
852 The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function.Hum Mol Genet. 2014 May 1;23(9):2428-39. doi: 10.1093/hmg/ddt638. Epub 2013 Dec 13.
853 Tissue slice grafts of human renal cell carcinoma: an authentic preclinical model with high engraftment rate and metastatic potential.Urol Oncol. 2014 Jan;32(1):43.e23-30. doi: 10.1016/j.urolonc.2013.05.008. Epub 2013 Aug 2.
854 RALY RNA binding protein-like reduced expression is associated with poor prognosis in clear cell renal cell carcinoma.Asian Pac J Cancer Prev. 2012;13(7):3403-8. doi: 10.7314/apjcp.2012.13.7.3403.
855 High expression of Ran GTPase is associated with local invasion and metastasis of human clear cell renal cell carcinoma.Int J Cancer. 2008 May 15;122(10):2391-7. doi: 10.1002/ijc.23400.
856 miR-28-5p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B.Oncotarget. 2016 Nov 8;7(45):73888-73902. doi: 10.18632/oncotarget.12516.
857 Rap1GAP regulates renal cell carcinoma invasion.Cancer Lett. 2012 Jul 1;320(1):65-71. doi: 10.1016/j.canlet.2012.01.022. Epub 2012 Jan 20.
858 Rap2B promotes angiogenesis via PI3K/AKT/VEGF signaling pathway in human renal cell carcinoma.Tumour Biol. 2017 Jul;39(7):1010428317701653. doi: 10.1177/1010428317701653.
859 Preoperative serum cystatin-C as a potential biomarker for prognosis of renal cell carcinoma.PLoS One. 2017 Jun 6;12(6):e0178823. doi: 10.1371/journal.pone.0178823. eCollection 2017.
860 Expression and clinicopathological correlations of retinoid acid receptor responder protein 1 in renal cell carcinomas.Biomark Med. 2016 Jul;10(7):721-32. doi: 10.2217/bmm.16.12. Epub 2016 Jun 24.
861 Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis.Cancer Res. 2008 Oct 1;68(19):7887-96. doi: 10.1158/0008-5472.CAN-08-1734.
862 The expression of RNA-binding protein RBM38 decreased in renal cell carcinoma and represses renal cancer cell proliferation, migration, and invasion.Tumour Biol. 2017 May;39(5):1010428317701635. doi: 10.1177/1010428317701635.
863 Expression of Ring Box-1 protein and its relationship with Fuhrman grade and other clinical-pathological parameters in renal cell cancer.Urol Oncol. 2020 Jan;38(1):6.e17-6.e22. doi: 10.1016/j.urolonc.2019.09.019. Epub 2019 Oct 23.
864 Estrogen inhibits renal cell carcinoma cell progression through estrogen receptor- activation.PLoS One. 2013;8(2):e56667. doi: 10.1371/journal.pone.0056667. Epub 2013 Feb 27.
865 Prognostic biomarkers in renal cell carcinoma: is there a relationship with obesity?.Transl Androl Urol. 2019 May;8(Suppl 2):S138-S146. doi: 10.21037/tau.2018.11.10.
866 Expression of regulator of G protein signalling protein 5 (RGS5) in the tumour vasculature of human renal cell carcinoma.J Pathol. 2004 May;203(1):551-8. doi: 10.1002/path.1543.
867 Variability in the expression of polycomb proteins in different normal and tumoral tissues. A pilot study using tissue microarrays.Mod Pathol. 2006 May;19(5):684-94. doi: 10.1038/modpathol.3800577.
868 SETDB2 and RIOX2 are differentially expressed among renal cell tumor subtypes, associating with prognosis and metastization.Epigenetics. 2017;12(12):1057-1064. doi: 10.1080/15592294.2017.1385685. Epub 2018 Jan 22.
869 Parathyroid hormone-related protein. Evidence for secretion of a novel mid-region fragment by three different cell types.J Biol Chem. 1992 Sep 5;267(25):18236-43.
870 Differentiation between papillary and nonpapillary renal cell carcinomas by DNA analysis.J Natl Cancer Inst. 1989 Apr 5;81(7):527-30. doi: 10.1093/jnci/81.7.527.
871 Prognostic Value of RNASEH2A-, CDK1-, and CD151-Related Pathway Gene Profiling for Kidney Cancers.Int J Mol Sci. 2018 May 28;19(6):1586. doi: 10.3390/ijms19061586.
872 Really interesting new gene finger protein 121 is a tumor suppressor of renal cell carcinoma.Gene. 2018 Nov 15;676:322-328. doi: 10.1016/j.gene.2018.08.067. Epub 2018 Aug 25.
873 Network spatio-temporal analysis predicts disease stage-related genes and pathways in renal cell carcinoma.Genet Mol Res. 2016 May 6;15(2). doi: 10.4238/gmr.15028061.
874 Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5.Oncogene. 2005 May 12;24(21):3503-11. doi: 10.1038/sj.onc.1208509.
875 Programmed death-1 (PD-1) receptor/PD-1 ligand (PD-L1) expression in fumarate hydratase-deficient renal cell carcinoma.Ann Diagn Pathol. 2017 Aug;29:17-22. doi: 10.1016/j.anndiagpath.2017.04.007. Epub 2017 Apr 24.
876 Knockdown of ribosomal protein S15A inhibits human kidney cancer cell growth invitro and invivo.Mol Med Rep. 2019 Feb;19(2):1117-1127. doi: 10.3892/mmr.2018.9751. Epub 2018 Dec 12.
877 The ribosomal protein S6 in renal cell carcinoma: functional relevance and potential as biomarker.Oncotarget. 2016 Jan 5;7(1):418-32. doi: 10.18632/oncotarget.6225.
878 Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.Cell Death Differ. 2006 Apr;13(4):619-27. doi: 10.1038/sj.cdd.4401782.
879 Immunohistochemical characterization of renal tumors in patients with Birt-Hogg-Dub syndrome.Pathol Int. 2015 Mar;65(3):126-32. doi: 10.1111/pin.12254. Epub 2015 Jan 19.
880 S100A11 regulates renal carcinoma cell proliferation, invasion, and migration via the EGFR/Akt signaling pathway and E-cadherin.Tumour Biol. 2017 May;39(5):1010428317705337. doi: 10.1177/1010428317705337.
881 Restricted expression of calcium-binding protein S100A5 in human kidney.Biochem Biophys Res Commun. 2002 Mar 1;291(3):623-7. doi: 10.1006/bbrc.2002.6494.
882 Despite differential gene expression profiles pediatric MDS derived mesenchymal stromal cells display functionality in vitro.Stem Cell Res. 2015 Mar;14(2):198-210. doi: 10.1016/j.scr.2015.01.006. Epub 2015 Jan 28.
883 The long noncoding RNA HOTAIR activates the Hippo pathway by directly binding to SAV1 in renal cell carcinoma.Oncotarget. 2017 Apr 25;8(35):58654-58667. doi: 10.18632/oncotarget.17414. eCollection 2017 Aug 29.
884 Flow cytometric quantitation of the proliferation-associated nuclear antigen p105 and DNA content in patients with renal cell carcinoma.Cancer. 1996 Aug 15;78(4):819-26. doi: 10.1002/(SICI)1097-0142(19960815)78:4<819::AID-CNCR19>3.0.CO;2-Y.
885 Regulation of antitumor miR-144-5p targets oncogenes: Direct regulation of syndecan-3 and its clinical significance.Cancer Sci. 2018 Sep;109(9):2919-2936. doi: 10.1111/cas.13722. Epub 2018 Jul 28.
886 Selenoprotein M stimulates the proliferative and metastatic capacities of renal cell carcinoma through activating the PI3K/AKT/mTOR pathway.Cancer Med. 2019 Aug;8(10):4836-4844. doi: 10.1002/cam4.2403. Epub 2019 Jul 5.
887 Seminal plasma protein in renal cell carcinoma: expression of semenogelin I is a predictor for cancer progression and prognosis.Tumour Biol. 2014 Sep;35(9):9095-100. doi: 10.1007/s13277-014-2184-6. Epub 2014 Jun 11.
888 Regulation of carcinoma cell invasion by protein C inhibitor whose expression is decreased in renal cell carcinoma.Int J Cancer. 2004 Feb 10;108(4):516-23. doi: 10.1002/ijc.11594.
889 Increased expression of SET domain-containing proteins and decreased expression of Rad51in different classes of renal cell carcinoma.Biosci Rep. 2016 Jun 30;36(3):e00349. doi: 10.1042/BSR20160122. Print 2016 Jul.
890 MicroRNA expression profiling of Xp11 renal cell carcinoma.Hum Pathol. 2017 Sep;67:18-29. doi: 10.1016/j.humpath.2017.03.011. Epub 2017 Apr 12.
891 Cell-Free SHOX2 DNA Methylation in Blood as a Molecular Staging Parameter for Risk Stratification in Renal Cell Carcinoma Patients: A Prospective Observational Cohort Study.Clin Chem. 2019 Apr;65(4):559-568. doi: 10.1373/clinchem.2018.297549. Epub 2019 Jan 9.
892 Transcription factor Six2 induces a stem cell-like phenotype in renal cell carcinoma cells.FEBS Open Bio. 2019 Oct;9(10):1808-1816. doi: 10.1002/2211-5463.12721. Epub 2019 Sep 19.
893 Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma.Cancer Sci. 2017 Oct;108(10):2088-2101. doi: 10.1111/cas.13331. Epub 2017 Aug 19.
894 Targeted p21(WAF1/CIP1) activation by miR-1236 inhibits cell proliferation and correlates with favorable survival in renal cell carcinoma.Urol Oncol. 2016 Feb;34(2):59.e23-34. doi: 10.1016/j.urolonc.2015.08.014. Epub 2015 Sep 28.
895 Promoter CpG island methylation in ion transport mechanisms and associated dietary intakes jointly influence the risk of clear-cell renal cell cancer.Int J Epidemiol. 2017 Apr 1;46(2):622-631. doi: 10.1093/ije/dyw266.
896 Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells.Mol Cell Biol. 2015 Aug;35(15):2684-98. doi: 10.1128/MCB.00019-15. Epub 2015 May 26.
897 Calcitriol inhibits migration and invasion of renal cell carcinoma cells by suppressing Smad2/3-, STAT3- and -catenin-mediated epithelial-mesenchymal transition.Cancer Sci. 2020 Jan;111(1):59-71. doi: 10.1111/cas.14237.
898 SWI/SNF protein expression status in fumarate hydratase-deficient renal cell carcinoma: immunohistochemical analysis of 32 tumors from 28 patients.Hum Pathol. 2018 Jul;77:139-146. doi: 10.1016/j.humpath.2018.04.004. Epub 2018 Apr 22.
899 Imaging Review of New and Emerging Sinonasal Tumors and Tumor-Like Entities from the Fourth Edition of the World Health Organization Classification of Head and Neck Tumors.AJNR Am J Neuroradiol. 2019 Apr;40(4):584-590. doi: 10.3174/ajnr.A5978. Epub 2019 Feb 14.
900 Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome-Associated Renal Cell Carcinoma Showing High FDG Uptake.Clin Nucl Med. 2019 May;44(5):420-423. doi: 10.1097/RLU.0000000000002495.
901 Reduction of transforming growth factor-beta type II receptor is caused by the enhanced ubiquitin-dependent degradation in human renal cell carcinoma.Int J Cancer. 2010 Oct 1;127(7):1517-25. doi: 10.1002/ijc.25164.
902 LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-B/p50 and SLUG.Biomed Pharmacother. 2019 Oct;118:109382. doi: 10.1016/j.biopha.2019.109382. Epub 2019 Aug 28.
903 Classic SRY-box protein SOX7 functions as a tumor suppressor regulating WNT signaling and is methylated in renal cell carcinoma.FASEB J. 2019 Jan;33(1):254-263. doi: 10.1096/fj.201701453RR. Epub 2018 Jun 29.
904 Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma.Am J Pathol. 2013 Jun;182(6):2191-203. doi: 10.1016/j.ajpath.2013.02.024. Epub 2013 Apr 17.
905 MicroRNA-200a-3p suppresses tumor proliferation and induces apoptosis by targeting SPAG9 in renal cell carcinoma.Biochem Biophys Res Commun. 2016 Feb 12;470(3):620-626. doi: 10.1016/j.bbrc.2016.01.095. Epub 2016 Jan 23.
906 SPARCL1 suppresses cell migration and invasion in renal cell carcinoma.Mol Med Rep. 2017 Nov;16(5):7784-7790. doi: 10.3892/mmr.2017.7535. Epub 2017 Sep 20.
907 Tumor-associated trypsin inhibitor in normal and malignant renal tissue and in serum of renal-cell carcinoma patients.Int J Cancer. 1999 Nov 12;83(4):486-90. doi: 10.1002/(sici)1097-0215(19991112)83:4<486::aid-ijc9>3.0.co;2-o.
908 Speckle-type POZ protein as a diagnostic biomarker in renal cell carcinoma.J Cancer Res Ther. 2018 Jul-Sep;14(5):977-982. doi: 10.4103/jcrt.JCRT_942_15.
909 Sprouty2 is associated with prognosis and suppresses cell proliferation and invasion in renal cell carcinoma.Urology. 2013 Jul;82(1):253.e1-7. doi: 10.1016/j.urology.2013.02.051. Epub 2013 May 17.
910 SPTLC1 inhibits cell growth via modulating Akt/FOXO1 pathway in renal cell carcinoma cells.Biochem Biophys Res Commun. 2019 Nov 26;520(1):1-7. doi: 10.1016/j.bbrc.2019.09.073. Epub 2019 Sep 22.
911 Identification and characterization of human leukocyte antigen class I ligands in renal cell carcinoma cells.Proteomics. 2011 Jun;11(12):2528-41. doi: 10.1002/pmic.201000486. Epub 2011 May 18.
912 Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dub tumour suppressor gene (FLCN).Oncogene. 2014 Feb 20;33(8):956-65. doi: 10.1038/onc.2013.27. Epub 2013 Feb 18.
913 Human alpha2,3-sialyltransferase (ST3Gal II) is a stage-specific embryonic antigen-4 synthase.J Biol Chem. 2003 Jul 18;278(29):26474-9. doi: 10.1074/jbc.M213223200. Epub 2003 Apr 25.
914 MiR-193a-3p and miR-224 mediate renal cell carcinoma progression by targeting alpha-2,3-sialyltransferase IV and the phosphatidylinositol 3 kinase/Akt pathway.Mol Carcinog. 2018 Aug;57(8):1067-1077. doi: 10.1002/mc.22826. Epub 2018 May 2.
915 Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors.Mol Carcinog. 2001 Sep;32(1):44-53. doi: 10.1002/mc.1063.
916 Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells.Int J Mol Sci. 2018 Oct 22;19(10):3280. doi: 10.3390/ijms19103280.
917 AIF downregulation and its interaction with STK3 in renal cell carcinoma.PLoS One. 2014 Jul 3;9(7):e100824. doi: 10.1371/journal.pone.0100824. eCollection 2014.
918 SUSD2 is frequently downregulated and functions as a tumor suppressor in RCC and lung cancer.Tumour Biol. 2016 Jul;37(7):9919-30. doi: 10.1007/s13277-015-4734-y. Epub 2016 Jan 27.
919 Analysis of the structural integrity of the TAP2 gene in renal cell carcinoma.Int J Oncol. 2003 Oct;23(4):991-9.
920 Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors.Cancer Res. 2002 Aug 1;62(15):4273-81.
921 Expression level of TBX3 gene in renal carcinoma and its clinical significance.Oncol Lett. 2018 Apr;15(4):4235-4240. doi: 10.3892/ol.2018.7841. Epub 2018 Jan 22.
922 Role of VHL gene mutation in human cancer.J Clin Oncol. 2004 Dec 15;22(24):4991-5004. doi: 10.1200/JCO.2004.05.061.
923 Restored expression levels of TET1 decrease the proliferation and migration of renal carcinoma cells.Mol Med Rep. 2015 Oct;12(4):4837-42. doi: 10.3892/mmr.2015.4058. Epub 2015 Jul 8.
924 TOP2A, HELLS, ATAD2, and TET3 Are Novel Prognostic Markers in Renal Cell Carcinoma.Urology. 2017 Apr;102:265.e1-265.e7. doi: 10.1016/j.urology.2016.12.050. Epub 2017 Jan 6.
925 Differential expression of activator protein-2 isoforms in renal cell carcinoma.Urology. 2004 Jul;64(1):162-7. doi: 10.1016/j.urology.2004.02.022.
926 New miRNA profiles accurately distinguish renal cell carcinomas and upper tract urothelial carcinomas from the normal kidney.PLoS One. 2014 Mar 12;9(3):e91646. doi: 10.1371/journal.pone.0091646. eCollection 2014.
927 Clinicopathologic and Molecular Analysis of the TFEB Fusion Variant Reveals New Members of TFEB Translocation Renal Cell Carcinomas (RCCs): Expanding the Genomic Spectrum.Am J Surg Pathol. 2020 Apr;44(4):477-489. doi: 10.1097/PAS.0000000000001408.
928 VHL-TGFBI signaling is involved in the synergy between 5-aza-2'-deoxycytidine and paclitaxel against human renal cell carcinoma.J BUON. 2017 Jul-Aug;22(4):1038-1045.
929 mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.Eur J Cancer. 2001 Oct;37(15):1839-46. doi: 10.1016/s0959-8049(01)00215-5.
930 Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.J Orthop Res. 2012 Feb;30(2):325-33. doi: 10.1002/jor.21500. Epub 2011 Aug 1.
931 The effect of TMEFF2 methylation on the tumor stage and survival outcome of clear cell renal cell carcinoma.Cancer Biomark. 2017;19(2):207-212. doi: 10.3233/CBM-161656.
932 Characterization of the role of TMEM45A in cancer cell sensitivity to cisplatin.Cell Death Dis. 2019 Dec 4;10(12):919. doi: 10.1038/s41419-019-2088-x.
933 Amplification-independent overexpression of thymosin beta-10 mRNA in human renal cell carcinoma.Ren Fail. 1994;16(2):243-54. doi: 10.3109/08860229409044864.
934 The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma.Mol Cancer. 2013 Oct 10;12(1):120. doi: 10.1186/1476-4598-12-120.
935 CpG dinucleotide-specific hypermethylation of the TNS3 gene promoter in human renal cell carcinoma.Epigenetics. 2013 Jul;8(7):739-47. doi: 10.4161/epi.25075. Epub 2013 May 24.
936 Analysis of p73 expression pattern in acute myeloid leukemias: lack of DeltaN-p73 expression is a frequent feature of acute promyelocytic leukemia.Leukemia. 2004 Nov;18(11):1804-9. doi: 10.1038/sj.leu.2403483.
937 Tumor Protein D52 (TPD52) Inhibits Growth and Metastasis in Renal Cell Carcinoma Cells Through the PI3K/Akt Signaling Pathway.Oncol Res. 2017 May 24;25(5):773-779. doi: 10.3727/096504016X14774889687280. Epub 2016 Nov 8.
938 Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma.J Cancer. 2019 May 21;10(10):2220-2228. doi: 10.7150/jca.28261. eCollection 2019.
939 ALK-TPM3 rearrangement in adult renal cell carcinoma: a case report and literature review.Diagn Pathol. 2019 Oct 18;14(1):112. doi: 10.1186/s13000-019-0879-0.
940 Patient samples of renal cell carcinoma show reduced expression of TRAF1 compared with normal kidney and functional studies in vitro indicate TRAF1 promotes apoptosis: potential for targeted therapy.Pathology. 2012 Aug;44(5):453-9. doi: 10.1097/PAT.0b013e3283557748.
941 Identification and validation of novel prognostic markers in Renal Cell Carcinoma.Dan Med J. 2017 Oct;64(10):B5339.
942 Valproic acid inhibits epithelialmesenchymal transition in renal cell carcinoma by decreasing SMAD4 expression.Mol Med Rep. 2017 Nov;16(5):6190-6199. doi: 10.3892/mmr.2017.7394. Epub 2017 Aug 29.
943 HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.Oncogene. 2005 Sep 22;24(42):6418-31. doi: 10.1038/sj.onc.1208794.
944 Nutrient-induced FNIP degradation by SCF-TRCP regulates FLCN complex localization and promotes renal cancer progression.Oncotarget. 2017 Feb 7;8(6):9947-9960. doi: 10.18632/oncotarget.14221.
945 Systematic Expression Analysis of Mitochondrial Complex I Identifies NDUFS1 as a Biomarker in Clear-Cell Renal-Cell Carcinoma.Clin Genitourin Cancer. 2017 Aug;15(4):e551-e562. doi: 10.1016/j.clgc.2016.11.010. Epub 2016 Dec 1.
946 Quantitative Global Proteome and Lysine Succinylome Analyses Reveal the Effects of Energy Metabolism in Renal Cell Carcinoma.Proteomics. 2018 Oct;18(19):e1800001. doi: 10.1002/pmic.201800001. Epub 2018 Sep 5.
947 Thymoquinone inhibits metastatic phenotype and epithelialmesenchymal transition in renal cell carcinoma by regulating the LKB1/AMPK signaling pathway.Oncol Rep. 2018 Sep;40(3):1443-1450. doi: 10.3892/or.2018.6519. Epub 2018 Jun 25.